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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Ligand | BDBM254002 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assays (DELFIA) | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 2±n/a nM | ||
| Comments | extracted | ||
| Citation |  Reiser, U 6-alkynyl-pyridine derivatives US Patent US9481673 Publication Date 11/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Baculoviral IAP repeat-containing protein 2 [256-363] | |||
| Name: | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 12600.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human cIAP BIR3 domain (256-363 aa) | ||
| Residue: | 108 | ||
| Sequence: |
| ||
| BDBM254002 | |||
| n/a | |||
| Name | BDBM254002 | ||
| Synonyms: | US9481673, (S)-12 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H30N8O2 | ||
| Mol. Mass. | 582.6544 | ||
| SMILES | CN[C@@H](C)C(=O)Nc1ccc(-c2c(nc3cc(C)ccn23)-c2cnc(C)nc2)c(n1)C#Cc1ccc2n(C)c(=O)ccc2c1 |r,wU:2.2,(-6.67,-4.1,;-8,-3.33,;-8,-1.79,;-9.34,-1.02,;-6.67,-1.02,;-6.67,.52,;-5.33,-1.79,;-4,-1.02,;-4,.52,;-2.67,1.29,;-1.33,.52,;,1.29,;,2.83,;1.46,3.3,;2.37,2.06,;3.9,1.9,;4.53,.49,;6.02,.09,;3.62,-.76,;2.09,-.6,;1.46,.81,;-1.09,3.92,;-.69,5.4,;-1.78,6.49,;-3.27,6.09,;-4.36,7.18,;-3.67,4.61,;-2.58,3.52,;-1.33,-1.02,;-2.67,-1.79,;,-1.79,;1.33,-2.56,;2.67,-3.33,;2.67,-4.87,;4,-5.64,;5.33,-4.87,;6.67,-5.64,;6.67,-7.18,;8,-4.87,;9.34,-5.64,;8,-3.33,;6.67,-2.56,;5.33,-3.33,;4,-2.56,)| | ||
| Structure | 
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