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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Ligand | BDBM254005 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assays (DELFIA) | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 2±n/a nM | ||
| Comments | extracted | ||
| Citation |  Reiser, U 6-alkynyl-pyridine derivatives US Patent US9481673 Publication Date 11/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Baculoviral IAP repeat-containing protein 2 [256-363] | |||
| Name: | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 12600.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human cIAP BIR3 domain (256-363 aa) | ||
| Residue: | 108 | ||
| Sequence: |
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| BDBM254005 | |||
| n/a | |||
| Name | BDBM254005 | ||
| Synonyms: | US9481673, (S)-15 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H28ClN7O2 | ||
| Mol. Mass. | 602.085 | ||
| SMILES | CN[C@@H](C)C(=O)Nc1ccc(-c2c(nc3cc(Cl)ccn23)-c2cccnc2OC)c(n1)C#Cc1ccc2c(C)nccc2c1 |r,wU:2.2,(-6,-4.16,;-7.34,-3.39,;-7.34,-1.85,;-8.67,-1.08,;-6,-1.08,;-6,.46,;-4.67,-1.85,;-3.33,-1.08,;-3.33,.46,;-2,1.23,;-.67,.46,;.67,1.23,;.67,2.77,;2.13,3.25,;3.04,2,;4.57,1.84,;5.19,.44,;6.68,.04,;4.29,-.81,;2.76,-.65,;2.13,.76,;-.42,3.86,;-1.91,3.46,;-3,4.55,;-2.6,6.04,;-1.11,6.44,;-.02,5.35,;1.46,5.75,;1.86,7.24,;-.67,-1.08,;-2,-1.85,;.67,-1.85,;2,-2.62,;3.33,-3.39,;3.33,-4.93,;4.67,-5.7,;6,-4.93,;7.34,-5.7,;7.34,-7.24,;8.67,-4.93,;8.67,-3.39,;7.34,-2.62,;6,-3.39,;4.67,-2.62,)| | ||
| Structure | 
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