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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Ligand | BDBM254006 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assays (DELFIA) | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 2±n/a nM | ||
| Comments | extracted | ||
| Citation |  Reiser, U 6-alkynyl-pyridine derivatives US Patent US9481673 Publication Date 11/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Baculoviral IAP repeat-containing protein 2 [256-363] | |||
| Name: | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 12600.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human cIAP BIR3 domain (256-363 aa) | ||
| Residue: | 108 | ||
| Sequence: |
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| BDBM254006 | |||
| n/a | |||
| Name | BDBM254006 | ||
| Synonyms: | US9481673, (S)-16 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H29N7O2 | ||
| Mol. Mass. | 567.6398 | ||
| SMILES | CN[C@@H](C)C(=O)Nc1ccc(-c2c(nc3ccccn23)-c2cccnc2OC)c(n1)C#Cc1ccc2c(C)nccc2c1 |r,wU:2.2,(-6,-4.23,;-7.34,-3.46,;-7.34,-1.92,;-8.67,-1.15,;-6,-1.15,;-6,.39,;-4.67,-1.92,;-3.33,-1.15,;-3.33,.39,;-2,1.16,;-.67,.39,;.67,1.16,;.51,2.69,;1.91,3.32,;2.94,2.17,;4.48,2.17,;5.25,.84,;4.48,-.49,;2.94,-.49,;2.17,.84,;-.83,3.46,;-2.16,2.69,;-3.5,3.46,;-3.5,5,;-2.16,5.77,;-.83,5,;.51,5.77,;.51,7.31,;-.67,-1.15,;-2,-1.92,;.67,-1.92,;2,-2.69,;3.33,-3.46,;3.33,-5,;4.67,-5.77,;6,-5,;7.34,-5.77,;7.34,-7.31,;8.67,-5,;8.67,-3.46,;7.34,-2.69,;6,-3.46,;4.67,-2.69,)| | ||
| Structure | 
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