| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-dependent protein kinase catalytic subunit alpha |
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| Ligand | BDBM258596 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competition Binding Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 6.09±n/a nM |
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| Comments | extracted |
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| Citation |  Akama, T; Jarnagin, K; Zhang, Y; Zhou, Y; Plattner, JJ; Sullivan, DC Boron-containing small molecules US Patent US9493490 Publication Date 11/15/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-dependent protein kinase catalytic subunit alpha |
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| Name: | cAMP-dependent protein kinase catalytic subunit alpha |
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| Synonyms: | KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit |
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| Type: | Enzyme Catalytic Subunit |
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| Mol. Mass.: | 40598.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 351 |
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| Sequence: | MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
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|
|
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| BDBM258596 |
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| n/a |
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| Name | BDBM258596 |
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| Synonyms: | US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)-7-methylbenzo[c][1,2]oxaborol-1(3H)-ol | US9493490, E | US9493490, Example 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17BFNO3 |
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| Mol. Mass. | 301.12 |
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| SMILES | CC(N)c1ccc(Oc2ccc3COB(O)c3c2C)c(F)c1 |
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| Structure | 
|
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