| Reaction Details |
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 | Report a problem with these data |
| Target | Melanin-concentrating hormone receptor 1 [E4Q,A5T] |
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| Ligand | BDBM258693 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| pH | 7.4±n/a |
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| Ki | 0.75±n/a nM |
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| Comments | extracted |
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| Citation |  Washburn, WN; Murugaiah Subbaiah, MA; Ahmad, S Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists US Patent US9499482 Publication Date 11/22/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanin-concentrating hormone receptor 1 [E4Q,A5T] |
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| Name: | Melanin-concentrating hormone receptor 1 [E4Q,A5T] |
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| Synonyms: | GPR24 | MCHR1 | MCHR1_HUMAN | Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T) | SLC1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 46077.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99705 (E4Q, A5T) |
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| Residue: | 422 |
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| Sequence: | MSVQTMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARL
WEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTIC
LLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHF
GETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS
FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRI
LQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVY
LYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESK
GT
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| BDBM258693 |
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| n/a |
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| Name | BDBM258693 |
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| Synonyms: | US9499482, 92 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29ClN2O3 |
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| Mol. Mass. | 440.962 |
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| SMILES | Clc1cc(ccc1OCCN1CCCC1)N1CC[C@H](Oc2ccc(cc2)C2CC2)C1=O |r| |
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| Structure | 
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