| Reaction Details |
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 | Report a problem with these data |
| Target | Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Ligand | BDBM259516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | 0.478±n/a nM |
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| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, X Quinazolinone compounds and derivatives thereof US Patent US9505749 Publication Date 11/29/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Name: | Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Synonyms: | PARP5B | TANK2 | TNKL | TNKS2 | TNKS2_HUMAN | Tankyrase-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 24581.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 946-1162 |
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| Residue: | 217 |
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| Sequence: | LNTSGSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKL
WERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENS
SKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSV
TGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPEG
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| BDBM259516 |
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| n/a |
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| Name | BDBM259516 |
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| Synonyms: | US9505749, 27 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24ClN5O3 |
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| Mol. Mass. | 465.932 |
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| SMILES | Clc1ccc2n(C3CCN(CC3)C(=O)CCCc3nc4ccccc4c(=O)[nH]3)c(=O)[nH]c2c1 |
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| Structure | 
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