Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCannabinoid receptor 2
LigandBDBM260139
Substrate/Competitorn/a
Meas. Tech.cAMP Assay
Temperature310.15±n/a K
EC50 0.3±n/a nM
Commentsextracted
Citation Frei BGobbi LGrether UKimbara ANettekoven MRoever SRogers-Evans MSchulz-Gasch T Pyridine derivatives US Patent  US9522886 Publication Date 12/20/2016
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM260139
n/a
NameBDBM260139
Synonyms:US9522886, 87
TypeSmall organic molecule
Emp. Form.C21H22FN3O4
Mol. Mass.399.4155
SMILESNC(=O)CC1(CCOC1)NC(=O)c1ccc(C2CC2)c(Oc2ccc(F)cc2)n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: