| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V1b receptor |
|---|
| Ligand | BDBM260220 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 277.15±n/a K |
|---|
| IC50 | 2.6±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Yoshinaga, M; Kuwada, T; Miyakoshi, N; Ishizaka, T; Wakasugi, D; Shirokawa, S; Hattori, N; Shimazaki, Y Azole derivative US Patent US9522914 Publication Date 12/20/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V1b receptor |
|---|
| Name: | Vasopressin V1b receptor |
|---|
| Synonyms: | AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 46985.01 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47901 |
|---|
| Residue: | 424 |
|---|
| Sequence: | MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
TIIF
|
|
|
|---|
| BDBM260220 |
|---|
| n/a |
|---|
| Name | BDBM260220 |
|---|
| Synonyms: | US9522914, A-22 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H35FN4O3 |
|---|
| Mol. Mass. | 506.6116 |
|---|
| SMILES | COc1cc(ccc1F)-c1nc(cn1CC(=O)NC(C)C)-c1ccc(CCN2C3CCC2COC3)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
