| Reaction Details |
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 | Report a problem with these data |
| Target | Purinergic receptor P2Y1 |
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| Ligand | BDBM50045624 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay (SPA) |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 13.0±n/a nM |
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| Comments | extracted |
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| Citation |  L'Heureux A; Hiebert S; Hu C; Lam PY; Lloyd J; Pi Z; Qiao JX; Thibeault C; Tora GO; Yang W; Wang Y; Wang TC; Bowsher MS; Rejean R 7-hydroxy-indolinyl antagonists of P2Y1 receptor US Patent US9540323 Publication Date 1/10/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Purinergic receptor P2Y1 |
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| Name: | Purinergic receptor P2Y1 |
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| Synonyms: | ATP receptor | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50045624 |
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| n/a |
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| Name | BDBM50045624 |
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| Synonyms: | CHEMBL3314304 | US9540323, 209 | US9540323, example 209 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H23ClFN5O2S |
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| Mol. Mass. | 560.042 |
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| SMILES | CC1(C)CN(c2c1c(ccc2O)-c1ccc(F)cc1)c1ccccc1NC(=O)Nc1nc2ccc(Cl)nc2s1 |
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| Structure | 
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