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TargetPurinergic receptor P2Y1
LigandBDBM50045624
Substrate/Competitorn/a
Meas. Tech.Scintillation Proximity Assay (SPA)
pH7.4±n/a
Temperature298.15±n/a K
Ki 13.0±n/a nM
Commentsextracted
Citation L'Heureux AHiebert SHu CLam PYLloyd JPi ZQiao JXThibeault CTora GOYang WWang YWang TCBowsher MSRejean R 7-hydroxy-indolinyl antagonists of P2Y1 receptor US Patent  US9540323 Publication Date 1/10/2017
More Info.:Get all data from this article,  Assay Method
 
Purinergic receptor P2Y1
Name:Purinergic receptor P2Y1
Synonyms:ATP receptor | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor
Type:Enzyme
Mol. Mass.:42090.25
Organism:Homo sapiens (Human)
Description:P47900
Residue:373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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  Blast E-value cutoff:
BDBM50045624
n/a
NameBDBM50045624
Synonyms:CHEMBL3314304 | US9540323, 209 | US9540323, example 209
TypeSmall organic molecule
Emp. Form.C29H23ClFN5O2S
Mol. Mass.560.042
SMILESCC1(C)CN(c2c1c(ccc2O)-c1ccc(F)cc1)c1ccccc1NC(=O)Nc1nc2ccc(Cl)nc2s1
Structure
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