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TargetGlycogen Synthase Kinase-3, beta
LigandBDBM6866
Substrate/CompetitorGSK-3 Peptide Substrate
Meas. Tech.Kinase Inhibition Assay
IC50 41±n/a nM
Citation Lin R; Connolly PJ; Huang S; Wetter SK; Lu Y; Murray WV; Emanuel SL; Gruninger RH; Fuentes-Pesquera AR; Rugg CA; Middleton SA; Jolliffe LK 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities. J Med Chem 48:4208-11 (2005) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Glycogen Synthase Kinase-3, beta
Name:Glycogen Synthase Kinase-3, beta
Synonyms:GSK-3, beta
Type:Enzyme fragment
Mol. Mass.:1767.89
Organism:Oryctolagus cuniculus (rabbit)
Description:Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli.. Only partial sequence is available.
Residue:17
Sequence:
xtsfaesxkp vqqpsafgs
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM6866
GSK-3 Peptide Substrate
Name:GSK-3 Peptide Substrate
Synonyms:n/a
Type:Peptide
Mol. Mass.:3277.76
Organism:n/a
Description:n/a
Residue:27
Sequence:
(Biotin)KRREILSRRP(phospho)SYR-Amide