| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta [7-25] |
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| Ligand | BDBM6878 |
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| Substrate/Competitor | GSK-3 Peptide Substrate |
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| Meas. Tech. | Kinase Inhibition Assay |
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| IC50 | 140±n/a nM |
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| Citation |  Lin, R; Connolly, PJ; Huang, S; Wetter, SK; Lu, Y; Murray, WV; Emanuel, SL; Gruninger, RH; Fuentes-Pesquera, AR; Rugg, CA; Middleton, SA; Jolliffe, LK 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities. J Med Chem48:4208-11 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Glycogen synthase kinase-3 beta [7-25] |
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| Name: | Glycogen synthase kinase-3 beta [7-25] |
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| Synonyms: | G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta |
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| Type: | Enzyme fragment |
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| Mol. Mass.: | 1972.14 |
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| Organism: | Oryctolagus cuniculus (rabbit) |
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| Description: | Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli..
Only partial sequence is available. |
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| Residue: | 19 |
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| Sequence: | |
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| BDBM6878 |
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| GSK-3 Peptide Substrate |
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| Name: | GSK-3 Peptide Substrate |
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| Synonyms: | n/a |
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| Type: | Peptide |
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| Mol. Mass.: | 3277.76 |
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| Organism: | n/a |
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| Description: | n/a |
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| Residue: | 27 |
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| Sequence: | (Biotin)KRREILSRRP(phospho)SYR-Amide
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