| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM156557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | enzyme assay |
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| IC50 | 0.730±n/a nM |
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| Citation |  Roberts, E; Guerrero, MA; Urbano, M; Rosen, H Kappa opioid ligands US Patent US10118915 Publication Date 11/6/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM156557 |
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| n/a |
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| Name | BDBM156557 |
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| Synonyms: | US10118915, Compound 337 | US9682966, 337 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H35N5O2 |
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| Mol. Mass. | 461.5991 |
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| SMILES | CO[C@H]1CN(CC[C@H]1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(no1)C1CC1 |r| |
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| Structure | 
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