| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform C of Bromodomain-containing protein 4 (Short) |
|---|
| Ligand | BDBM50365262 |
|---|
| Substrate/Competitor | n/a |
|---|
| Kd | 3800±n/a nM |
|---|
| Citation |  Landau, SB; Kagey, M Bromodomain inhibitors US Patent US10124009 Publication Date 11/13/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isoform C of Bromodomain-containing protein 4 (Short) |
|---|
| Name: | Isoform C of Bromodomain-containing protein 4 (Short) |
|---|
| Synonyms: | BET bromodomain 4 (BRD4) | BRD4 | BRD4_HUMAN | Bromodomain-containing protein 4 (Short) | HUNK1 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 80477.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O60885-2 |
|---|
| Residue: | 722 |
|---|
| Sequence: | MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETG
PA
|
|
|
|---|
| BDBM50365262 |
|---|
| n/a |
|---|
| Name | BDBM50365262 |
|---|
| Synonyms: | (+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10124009, Compound (S)-JQ1 | US10202360, Example JQ-1 | US10308662, Compound JQ-1 | US10407441, Compound (S)-JQ1 | US10617680, Example JQ-1 | US10881668, Compound JQ1 | US10925881, Name (S)-JQ1 | US11020380, Example JQ-1 | US11078188, Example (+)-JQ1 | US11279703, TABLE 6.180 | US11427593, Compound JQ1 | US11466034, Example (+)-JQ1 | US9320741, (S)-JQ1 | US9695172, JQ1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25ClN4O2S |
|---|
| Mol. Mass. | 456.988 |
|---|
| SMILES | Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| |
|---|
| Structure | 
|
|---|
Search and Browse
