| Reaction Details |
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 | Report a problem with these data |
| Target | Small conductance calcium-activated potassium channel protein 1 |
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| Ligand | BDBM168436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Voltage-Clamp Assay |
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| pH | 7.35±n/a |
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| Temperature | 298.15±n/a K |
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| EC50 | >1.00e+5±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC; Wulff, H; Coleman, N; Jenkins, DP Methods for treating seizure disorders and pain US Patent US9675591 Publication Date 6/13/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Small conductance calcium-activated potassium channel protein 1 |
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| Name: | Small conductance calcium-activated potassium channel protein 1 |
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| Synonyms: | KCNN1 | KCNN1_HUMAN | SK | Small conductance calcium-activated potassium channel protein 1 | Small conductance calcium-activated potassium channel protein 1 (KCa2.1) |
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| Type: | Protein |
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| Mol. Mass.: | 60005.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92952 |
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| Residue: | 543 |
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| Sequence: | MNSHSYNGSVGRPLGSGPGALGRDPPDPEAGHPPQPPHSPGLQVVVAKSEPARPSPGSPR
GQPQDQDDDEDDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVV
MVTETELSWGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIA
MTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYL
LGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWT
VRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTAL
VVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARV
RKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEA
RLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPS
DCG
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|
|
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| BDBM168436 |
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| n/a |
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| Name | BDBM168436 |
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| Synonyms: | US9675591, SKA-19 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H5F3N2S2 |
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| Mol. Mass. | 250.264 |
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| SMILES | Nc1nc2ccc(SC(F)(F)F)cc2s1 |
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| Structure | 
|
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