| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelin-1 |
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| Ligand | BDBM172579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ET-1 Assay |
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| EC50 | <50000±n/a nM |
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| Citation |  PubChem, PC; Buckman, BO; Nicholas, JB; Ramphal, JY; Emayan, K; Seiwert, SD Anti-fibrotic pyridinones US Patent US9675593 Publication Date 6/13/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelin-1 |
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| Name: | Endothelin-1 |
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| Synonyms: | EDN1 | EDN1_HUMAN | PPET1 | Preproendothelin-1 |
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| Type: | Protein |
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| Mol. Mass.: | 24444.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05305 |
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| Residue: | 212 |
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| Sequence: | MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
|
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|
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| BDBM172579 |
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| n/a |
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| Name | BDBM172579 |
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| Synonyms: | US9675593, 634 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13F3N6O2 |
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| Mol. Mass. | 390.3193 |
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| SMILES | CCn1nnc2c(cn(-c3ccc(OC(F)(F)F)cc3)c(=O)c12)-c1cn[nH]c1 |
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| Structure | 
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