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TargetGlycogen synthase kinase-3 beta [7-25]
LigandBDBM7876
Substrate/CompetitorGSK-3 Peptide Substrate
Meas. Tech.Kinase Inhibition Assay
Temperature310.15±n/a K
IC50 500±n/a nM
Commentsextracted
Citation Conde, S; Perez, DI; Martinez, A; Perez, C; Moreno, FJ Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3 beta) from a library of compound searching. J Med Chem46:4631-3 (2003) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Glycogen synthase kinase-3 beta [7-25]
Name:Glycogen synthase kinase-3 beta [7-25]
Synonyms:G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta
Type:Enzyme fragment
Mol. Mass.:1972.14
Organism:Oryctolagus cuniculus (rabbit)
Description:Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli.. Only partial sequence is available.
Residue:19
Sequence:
TTSFAESCKPVQQPSAFGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM7876
GSK-3 Peptide Substrate
Name:GSK-3 Peptide Substrate
Synonyms:GS-1 Peptide | Phospho-GS2 Substrate Peptide
Type:Peptide
Mol. Mass.:3045.17
Organism:n/a
Description:n/a
Residue:27
Sequence:
YRRAAVPPSPSLSRHSSPHQS(PO4)EDEEE