Search and Browse
Download
Enter Data
|
Assay Method Information |
|
| | Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) |
| Description: | Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provider: Scripps Florida Network: Molecular Library Screening Center Network (MLSCN) Grant Proposal Number ML00111 Grant Proposal PI: Philip LoGrasso External Assay ID: JNK3_INH_TR-FRET_1536_IC50 Name: Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) Description: The c-Jun N-Terminal Kinases (JNK) are members of the mitogen activated protein (MAP) kinase family of enzymes. Among the many substrates phosphorylated by JNKs is the N-terminal activation domain of the transcription factor c-Jun. So far, three genes have been found to encode for JNK kinases, namely JNK1, JNK2 and JNK3. Whereas JNK1 and JNK2 exhibit a ubiquitous human expression pattern, JNK3 expression appears to be largely restricted to the brain [1]. JNKs are activated by a variety of stimuli including cytokines, ultra violet light, |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |
|
Home |
| |
Search |
| |
Deposit |
| |
SiteMap |
| |
About us |
| |
Email us |
| |
Info |
|
©2000 BindingDB. All rights reserved. |
|||||||||||||