BindingDB logo
myBDB logout

Assay Method Information

Assay Name:  Luminescence-based dose response biochemical high throughput screening assay for inhibitors of the Heat Shock Protein 90 (HSP90)
Description:  Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TSRI) Assay Provider: Robert Matts, Oklahoma State University Network: Molecular Libraries Probe Production Centers Network (MLPCN) Grant Proposal Number: 1 X01 MH083240-01 Grant Proposal PI: Robert Matts, Oklahoma State University External Assay ID: HSP90_INH_LUMI_1536_3XIC50 Name: Luminescence-based dose response biochemical high throughput screening assay for inhibitors of the Heat Shock Protein 90 (HSP90) Description: Hsp90 is a ubiquitously conserved molecular chaperone (1, 2) that assists the folding of client substrates involved in a variety of human disorders characterized by dysregulated cell proliferation (ie, cancer and viral infections), accumulation of protein aggregates (ie, neurodegenerative diseases) and stress-induced apoptotic cell death (ie, multiple sclerosis) (3). Its diverse biology stems in part from interactions
Affinity data for this assay
 

If you find an error in this entry please send us an E-mail
   
    

Home

|

Search

|

Deposit

|

SiteMap

|

About us

|

Email us

|

Info

 
Last update November 1, 2007
©2000 BindingDB. All rights reserved.