Assay Method Information |
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| Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 |
Description: | Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inhibitor. Saccharomyces strain expressing B-galactosidase driven by glucocorticoid response element is exposed to compounds. Loss of signal indicates interference with hsp90 function. Expected Outcome: Reduction of signal indicates hsp90 inhibition by compound. |
Affinity data for this assay | |
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