Assay Method Information |
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| Dose response assay for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay II |
Description: | Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC_KCNQ2_Inh_HFCP_IWS_CRC) Center Affiliation: Johns Hopkins University, School of Medicine Screening Center PI: Min Li, Ph.D. Assay Provider: Min Li, Ph.D. Network: Molecular Libraries Probe Production Centers Network (MLPCN) Grant Proposal Number: 1 R03 DA027716-01 Grant Proposal PI: Min Li, Ph.D., Johns Hopkins University School of Medicine Assay Implementation: Haibo Yu Ph.D., Kaiping Xu, Shunyou Long M.S, David Meyers Ph.D., Meng Wu Ph.D., Owen McManus Ph.D. Name: Dose response assay for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay II Description: Voltage-gated potassium (K) channels are critical for neuronal function in excitable tissues such as brain and heart. They are also found in non-excitable tissues important for other functions such as hormone secretion, oxygen-sensing and immune responses. There are more than 100 genes in the human genome encoding different but |
Affinity data for this assay | |
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