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Assay Method Information

Assay Name:  ChEMBL_1627458
Description:  Positive allosteric modulation activity at human mGluR5A expressed in HEK293(ZF) cells co-expressing rat glutamate-aspartate transporter assessed as increase in L-glutamate-induced Ca2+ flux preincubated for 60 mins followed by L-glutamate addition measured for 100 sec by calcium-4 dye based FLIPR assay
Affinity data for this assay
 

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Last update November 1, 2007
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