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| | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
| Description: | Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assay Provider: Bert O'Malley, Baylor College of Medicine Network: Molecular Library Probe Production Centers Network (MLPCN) Grant Proposal Number: 5U19DK062434-09 Grant Proposal PI: Bert O'Malley, Baylor College of Medicine External Assay ID: SRC1_INH_LUMI_1536_3XIC50 DCSRUN for SRC3 Name: Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1). Description: Chemotherapeutic agents that target estrogen receptor alpha (ERa and growth factor signaling systems have been extensively pursued and developed for a long time (1-4). However, one of the most pressing limitations of currently established chemotherapeutic agents for breast cancer is the fact that breast cancers |
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