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| | Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) |
| Description: | Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_ACT_LUMI_1536_3XEC50 MDCSRUN (HTR2A) Serotonin (5-hydroxytryptamine; 5-HT) is an abundant neurotransmitter synthesized from the essential amino acid L-tryptophan and plays a significant role in appetite, platelet aggregation, pain perception, sleep, hormone secretion, sexual behavior, and thermoregulation. Serotonin mediates much of its actions by binding to and activating G |
| Affinity data for this assay | |
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