Assay Method Information |
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| Radioligand Displacement Assay (SR141716) |
Description: | Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values were determined. Selectivity of these compounds at CB1 versus CB2 was also determined by obtaining Ki values at either receptor using displacement of SR141716 ([3H]1 in membranes of CHO-K1 cells over-expressing either receptor. Data reported are average values from 3-6 measurements. |
Affinity data for this assay | |
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