Assay Method Information |
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| Competitive Binding Assay (KINOMEscan) |
Description: | For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEscan technology (Ambit Biosciences) (Karaman, et al. (2008) Nature biotechnology 26:127-132). 11-point Kd curves were determined for hits identified during the initial screen. |
Affinity data for this assay | |
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