Assay Method Information |
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| ChEMBL_858345 (CHEMBL2168560) |
Description: | Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of glutamate-stimulated IP accumulation incubated for 10 mins prior to glutamate challenge measured 30 mins post glutamate challenge by scintillation counter in presence of [3H]myo-inositol |
Affinity data for this assay | |
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