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Assay Method Information

Assay Name:  ChEMBL_858345 (CHEMBL2168560)
Description:  Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of glutamate-stimulated IP accumulation incubated for 10 mins prior to glutamate challenge measured 30 mins post glutamate challenge by scintillation counter in presence of [3H]myo-inositol
Affinity data for this assay
 

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Last update November 1, 2007
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