BindingDB Home

7,420 protein targets, 786,195 compounds, and 1,771,797 measurements.

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

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News and Messages

  • We have added a new Webservice, getLigandsByUniprots, which accepts list of UniProt IDs and returns all ligands for the proteins in the list that bind better than a user-specified threshold. A switch allows selection of results for all ligands, only ligands identified as commercially available, or only ligands identified as FDA-approved drugs. Another switch allows the default XML format to be replaced by JSON. (May 2016)
  • BindingDB is collaborating with the NDEx project to support annotation of biomolecular networks with small molecule binding data. This page provides further details, and you can view BindingDB as NDEx networks here. The NDEx Project provides an open-source framework where scientists and organizations can share, store, manipulate and publish biological network knowledge. (May 2016)
  • The Target Names page has a new column, Commercially Available Compounds, which provides links only to BindingDB data for commercially available compounds. To buy a compound, follow the "Purchase" link under "Ligand Links" in pages like this. (May 2016)

BindingDB Data Curation

BindingDB curates US Patents with protein-small molecule binding data. As of December 2019, BindingDB's patent dataset comprises:

  1. Patents: 3,414
  2. Binding measurements: 474,711
  3. Compounds: 259,058
  4. Target proteins: 1,697
  5. Assays: 4,970

BindingDB curates a set of journals not covered by other public databases. As of December 2019, the status of this curation effort is as follows:

BindingDB is supported by NIH's National Institute of General Medical Sciences (GM070064), and is located at the Skaggs School of Pharmacy and Pharmaceutical Sciences of the University of California San Diego