Compile Data Set for Download or QSAR

Found 565 hits for UniProtKB: O15055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140894 (CHEMBL3754467 | US10383880, Example 124) Show SMILES CN1CCCN(CC(O)Cn2c3ccccc3c3ccccc23)S1(=O)=O Show InChI InChI=1S/C19H23N3O3S/c1-20-11-6-12-21(26(20,24)25)13-15(23)14-22-18-9-4-2-7-16(18)17-8-3-5-10-19(17)22/h2-5,7-10,15,23H,6,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	726	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140895 (CHEMBL3753417 | US10383880, Example 4) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)c1ccccc1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C26H24N2O4S/c29-20(18-28-25-14-6-4-12-23(25)24-13-5-7-15-26(24)28)17-27(19-21-9-8-16-32-21)33(30,31)22-10-2-1-3-11-22/h1-16,20,29H,17-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140896 (CHEMBL3752727 | US10383880, Example 14) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)Cc1ccccc1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C27H26N2O4S/c30-22(18-29-26-14-6-4-12-24(26)25-13-5-7-15-27(25)29)17-28(19-23-11-8-16-33-23)34(31,32)20-21-9-2-1-3-10-21/h1-16,22,30H,17-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	415	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140904 (CHEMBL3752018 | US10383880, Example 113) Show SMILES CS(=O)(=O)NCC(O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C16H18N2O3S/c1-22(20,21)17-10-12(19)11-18-15-8-4-2-6-13(15)14-7-3-5-9-16(14)18/h2-9,12,17,19H,10-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140907 (CHEMBL1487843 | US10383880, Example 32) Show SMILES CN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C17H20N2O3S/c1-18(23(2,21)22)11-13(20)12-19-16-9-5-3-7-14(16)15-8-4-6-10-17(15)19/h3-10,13,20H,11-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	781	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140915 (CHEMBL3754372 | US10383880, Example 45) Show SMILES CCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C18H22N2O3S/c1-3-19(24(2,22)23)12-14(21)13-20-17-10-6-4-8-15(17)16-9-5-7-11-18(16)20/h4-11,14,21H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	505	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140918 (CHEMBL3752371) Show SMILES CCCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C19H24N2O3S/c1-3-12-20(25(2,23)24)13-15(22)14-21-18-10-6-4-8-16(18)17-9-5-7-11-19(17)21/h4-11,15,22H,3,12-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	408	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140919 (CHEMBL3753078 | US10383880, Example 46) Show SMILES CC(C)N(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C19H24N2O3S/c1-14(2)21(25(3,23)24)13-15(22)12-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,14-15,22H,12-13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	511	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140920 (CHEMBL3752323 | US10383880, Example 49) Show SMILES CC(C)CN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C20H26N2O3S/c1-15(2)12-21(26(3,24)25)13-16(23)14-22-19-10-6-4-8-17(19)18-9-5-7-11-20(18)22/h4-11,15-16,23H,12-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	178	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140921 (CHEMBL3753693 | US10383880, Example 56) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CC1 Show InChI InChI=1S/C19H22N2O3S/c1-25(23,24)21(14-10-11-14)13-15(22)12-20-18-8-4-2-6-16(18)17-7-3-5-9-19(17)20/h2-9,14-15,22H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	446	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140922 (CHEMBL3752819 | US10383880, Example 57) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCC1 Show InChI InChI=1S/C20H24N2O3S/c1-26(24,25)22(15-7-6-8-15)14-16(23)13-21-19-11-4-2-9-17(19)18-10-3-5-12-20(18)21/h2-5,9-12,15-16,23H,6-8,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	129	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140692 (CHEMBL3754517 | US10383880, Example 84) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C26H30N2O4S/c29-20(18-28-25-14-6-4-12-23(25)24-13-5-7-15-26(24)28)17-27(19-21-9-8-16-32-21)33(30,31)22-10-2-1-3-11-22/h4-9,12-16,20,22,29H,1-3,10-11,17-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140693 (CHEMBL3753394 | US10383880, Example 11) Show SMILES COCCS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C23H26N2O5S/c1-29-13-14-31(27,28)24(17-19-7-6-12-30-19)15-18(26)16-25-22-10-4-2-8-20(22)21-9-3-5-11-23(21)25/h2-12,18,26H,13-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140696 (CHEMBL3752613 | US10383880, Example 16) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C23H24N2O4S/c26-17(14-24(16-18-6-5-13-29-18)30(27,28)19-11-12-19)15-25-22-9-3-1-7-20(22)21-8-2-4-10-23(21)25/h1-10,13,17,19,26H,11-12,14-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	557	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140697 (CHEMBL3754783) Show SMILES CCCCS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C24H28N2O4S/c1-2-3-15-31(28,29)25(18-20-9-8-14-30-20)16-19(27)17-26-23-12-6-4-10-21(23)22-11-5-7-13-24(22)26/h4-14,19,27H,2-3,15-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	374	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140698 (CHEMBL3753223 | US10383880, Example 13) Show SMILES CC(C)CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C24H28N2O4S/c1-18(2)17-31(28,29)25(16-20-8-7-13-30-20)14-19(27)15-26-23-11-5-3-9-21(23)22-10-4-6-12-24(22)26/h3-13,18-19,27H,14-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	361	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140700 (CHEMBL3754797 | US10383880, Example 85) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCOC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C24H26N2O5S/c27-18(15-26-23-9-3-1-7-21(23)22-8-2-4-10-24(22)26)14-25(16-19-6-5-12-31-19)32(28,29)20-11-13-30-17-20/h1-10,12,18,20,27H,11,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140701 (CHEMBL3753497 | US10383880, Example 82) Show SMILES CC(C)S(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C23H26N2O4S/c1-17(2)30(27,28)24(16-19-8-7-13-29-19)14-18(26)15-25-22-11-5-3-9-20(22)21-10-4-6-12-23(21)25/h3-13,17-18,26H,14-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	438	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140702 (CHEMBL3753702 | US10383880, Example 3) Show SMILES CCCS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C23H26N2O4S/c1-2-14-30(27,28)24(17-19-8-7-13-29-19)15-18(26)16-25-22-11-5-3-9-20(22)21-10-4-6-12-23(21)25/h3-13,18,26H,2,14-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	516	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140703 (CHEMBL3754134 | US10383880, Example 2) Show SMILES CCS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C22H24N2O4S/c1-2-29(26,27)23(16-18-8-7-13-28-18)14-17(25)15-24-21-11-5-3-9-19(21)20-10-4-6-12-22(20)24/h3-13,17,25H,2,14-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	197	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM56256 (MLS000110334 | N-(3-carbazol-9-yl-2-hydroxy-propyl...) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C21H22N2O4S/c1-28(25,26)22(15-17-7-6-12-27-17)13-16(24)14-23-20-10-4-2-8-18(20)19-9-3-5-11-21(19)23/h2-12,16,24H,13-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	870	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140732 (CHEMBL3753313) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)c1ccccn1 Show InChI InChI=1S/C21H21N3O3S/c1-28(26,27)24(21-12-6-7-13-22-21)15-16(25)14-23-19-10-4-2-8-17(19)18-9-3-5-11-20(18)23/h2-13,16,25H,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140736 (CHEMBL3754710 | US10383880, Example 58) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCCC1 Show InChI InChI=1S/C21H26N2O3S/c1-27(25,26)23(16-8-2-3-9-16)15-17(24)14-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h4-7,10-13,16-17,24H,2-3,8-9,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	308	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140749 (CHEMBL3752740 | US10383880, Example 71) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCCCC1 Show InChI InChI=1S/C22H28N2O3S/c1-28(26,27)24(17-9-3-2-4-10-17)16-18(25)15-23-21-13-7-5-11-19(21)20-12-6-8-14-22(20)23/h5-8,11-14,17-18,25H,2-4,9-10,15-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	532	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140753 (CHEMBL3752876) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1COC1 Show InChI InChI=1S/C19H22N2O4S/c1-26(23,24)21(14-12-25-13-14)11-15(22)10-20-18-8-4-2-6-16(18)17-7-3-5-9-19(17)20/h2-9,14-15,22H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140756 (CHEMBL3753763) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCOCC1 Show InChI InChI=1S/C21H26N2O4S/c1-28(25,26)23(16-10-12-27-13-11-16)15-17(24)14-22-20-8-4-2-6-18(20)19-7-3-5-9-21(19)22/h2-9,16-17,24H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	819	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140758 (CHEMBL3752125 | US10383880, Example 133) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CC(F)(F)C1 Show InChI InChI=1S/C20H22F2N2O3S/c1-28(26,27)24(14-10-20(21,22)11-14)13-15(25)12-23-18-8-4-2-6-16(18)17-7-3-5-9-19(17)23/h2-9,14-15,25H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140759 (CHEMBL3752021 | US10383880, Example 128) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCC(F)(F)CC1 Show InChI InChI=1S/C22H26F2N2O3S/c1-30(28,29)26(16-10-12-22(23,24)13-11-16)15-17(27)14-25-20-8-4-2-6-18(20)19-7-3-5-9-21(19)25/h2-9,16-17,27H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140764 (CHEMBL3754396) Show SMILES COCCN(CC(O)Cn1c2ccccc2c2ccccc12)S(C)(=O)=O Show InChI InChI=1S/C19H24N2O4S/c1-25-12-11-20(26(2,23)24)13-15(22)14-21-18-9-5-3-7-16(18)17-8-4-6-10-19(17)21/h3-10,15,22H,11-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140765 (CHEMBL1446115 | US10383880, Example 23) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)c1ccccc1 Show InChI InChI=1S/C22H22N2O3S/c1-28(26,27)24(17-9-3-2-4-10-17)16-18(25)15-23-21-13-7-5-11-19(21)20-12-6-8-14-22(20)23/h2-14,18,25H,15-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	272	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140769 (CHEMBL3754502) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)c1ccccc1F Show InChI InChI=1S/C22H21FN2O3S/c1-29(27,28)25(22-13-7-4-10-19(22)23)15-16(26)14-24-20-11-5-2-8-17(20)18-9-3-6-12-21(18)24/h2-13,16,26H,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140884 (CHEMBL3752425) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)c1cccc(F)c1 Show InChI InChI=1S/C22H21FN2O3S/c1-29(27,28)25(17-8-6-7-16(23)13-17)15-18(26)14-24-21-11-4-2-9-19(21)20-10-3-5-12-22(20)24/h2-13,18,26H,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140885 (CHEMBL3752453 | US10383880, Example 24) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN2O3S/c1-29(27,28)25(17-12-10-16(23)11-13-17)15-18(26)14-24-21-8-4-2-6-19(21)20-7-3-5-9-22(20)24/h2-13,18,26H,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	939	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140886 (CHEMBL3753460 | US10383880, Example 44) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccccc1 Show InChI InChI=1S/C23H24N2O3S/c1-29(27,28)24(15-18-9-3-2-4-10-18)16-19(26)17-25-22-13-7-5-11-20(22)21-12-6-8-14-23(21)25/h2-14,19,26H,15-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	818	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140887 (CHEMBL3753709) Show SMILES OC(CN1CCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C17H18N2O3S/c20-13(11-18-9-10-23(18,21)22)12-19-16-7-3-1-5-14(16)15-6-2-4-8-17(15)19/h1-8,13,20H,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140888 (CHEMBL3753839 | US10383880, Example 20) Show SMILES OC(CN1CCCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C18H20N2O3S/c21-14(12-19-10-5-11-24(19,22)23)13-20-17-8-3-1-6-15(17)16-7-2-4-9-18(16)20/h1-4,6-9,14,21H,5,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	144	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140889 (CHEMBL3752502 | US10383880, Example 33) Show SMILES OC(CN1CCCCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C19H22N2O3S/c22-15(13-20-11-5-6-12-25(20,23)24)14-21-18-9-3-1-7-16(18)17-8-2-4-10-19(17)21/h1-4,7-10,15,22H,5-6,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	173	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140890 (CHEMBL3754594) Show SMILES OC(CN1CCOCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C18H20N2O4S/c21-14(11-19-9-10-24-13-25(19,22)23)12-20-17-7-3-1-5-15(17)16-6-2-4-8-18(16)20/h1-8,14,21H,9-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140891 (CHEMBL3753487) Show SMILES OC(CN1CCNS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C17H19N3O3S/c21-13(11-19-10-9-18-24(19,22)23)12-20-16-7-3-1-5-14(16)15-6-2-4-8-17(15)20/h1-8,13,18,21H,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140892 (CHEMBL3752737) Show SMILES CN1CCN(CC(O)Cn2c3ccccc3c3ccccc23)S1(=O)=O Show InChI InChI=1S/C18H21N3O3S/c1-19-10-11-20(25(19,23)24)12-14(22)13-21-17-8-4-2-6-15(17)16-7-3-5-9-18(16)21/h2-9,14,22H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140893 (CHEMBL3753932 | US10383880, Example 123) Show SMILES OC(CN1CCCNS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C18H21N3O3S/c22-14(12-20-11-5-10-19-25(20,23)24)13-21-17-8-3-1-6-15(17)16-7-2-4-9-18(16)21/h1-4,6-9,14,19,22H,5,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	384	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) Article DOI: 10.1016/j.bmcl.2015.12.102 BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356633 (1-(3-(9H-carbazol-9-yl)-2-hydroxypropyl)piperidin-...) Show SMILES OC(CN1CCCCC1=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C20H22N2O2/c23-15(13-21-12-6-5-11-20(21)24)14-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-4,7-10,15,23H,5-6,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	171	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356634 (1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- fluo...) Show SMILES OC(CN1CCCC(F)C1=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C20H21FN2O2/c21-17-8-5-11-22(20(17)25)12-14(24)13-23-18-9-3-1-6-15(18)16-7-2-4-10-19(16)23/h1-4,6-7,9-10,14,17,24H,5,8,11-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356635 (1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- meth...) Show SMILES CN1CCCN(CC(O)Cn2c3ccccc3c3ccccc23)C1=O Show InChI InChI=1S/C20H23N3O2/c1-21-11-6-12-22(20(21)25)13-15(24)14-23-18-9-4-2-7-16(18)17-8-3-5-10-19(17)23/h2-5,7-10,15,24H,6,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	736	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356636 (US10214507, Compound 71 | US10759777, Compound 71) Show SMILES OC(CN1CCCNC1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C19H19F2N3O2/c20-12-2-4-17-15(8-12)16-9-13(21)3-5-18(16)24(17)11-14(25)10-23-7-1-6-22-19(23)26/h2-5,8-9,14,25H,1,6-7,10-11H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	188	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356638 (1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl) tetrahy...) Show SMILES OC(CN1CCCNC1=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C19H21N3O2/c23-14(12-21-11-5-10-20-19(21)24)13-22-17-8-3-1-6-15(17)16-7-2-4-9-18(16)22/h1-4,6-9,14,23H,5,10-13H2,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	299	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356639 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...) Show SMILES OC(CN1CCNC1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C18H17F2N3O2/c19-11-1-3-16-14(7-11)15-8-12(20)2-4-17(15)23(16)10-13(24)9-22-6-5-21-18(22)25/h1-4,7-8,13,24H,5-6,9-10H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	389	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356640 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...) Show SMILES OC(CN1CCCCC1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C20H20F2N2O2/c21-13-4-6-18-16(9-13)17-10-14(22)5-7-19(17)24(18)12-15(25)11-23-8-2-1-3-20(23)26/h4-7,9-10,15,25H,1-3,8,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	192	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356641 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...) Show SMILES CCN1CCN(CC(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O Show InChI InChI=1S/C20H21F2N3O2/c1-2-23-7-8-24(20(23)27)11-15(26)12-25-18-5-3-13(21)9-16(18)17-10-14(22)4-6-19(17)25/h3-6,9-10,15,26H,2,7-8,11-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356642 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC(O)(CN1CCCCC1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C21H22F2N2O2/c1-21(27,12-24-9-3-2-4-20(24)26)13-25-18-7-5-14(22)10-16(18)17-11-15(23)6-8-19(17)25/h5-8,10-11,27H,2-4,9,12-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	536	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair

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