Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101546 (US8530494, 211 | US8530652, 125 | US8530652, 73) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.60 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101542 (US8530494, 207 | US8530652, 121 | US8530652, 69) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.90 | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50097131 (CHEMBL3580667) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human PAK4 | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101479 (US8524710, 56 | US8530652, 50 | US8530652, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.80 | n/a | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50389112 (CHEMBL2064556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PAK4 | J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101537 (US8530494, 204 | US8530652, 115 | US8530652, 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50600091 (CHEMBL5191406) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmc.2022.116700 BindingDB Entry DOI: 10.7270/Q2FN1B89 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50448771 (CHEMBL3128042) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to N-terminal GST-tagged recombinant human PAK4 kinase domain expressed in Escherichia coli using KKRNRRLSVA as substrate preincubat... | J Med Chem 57: 1033-45 (2014) Article DOI: 10.1021/jm401768t BindingDB Entry DOI: 10.7270/Q2F47QNW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM4838 (US8524710, 83 | US8530494, 13 | US8530652, 52) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.5 | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM4838 (US8524710, 83 | US8530494, 13 | US8530652, 52) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.5 | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101547 (US8530494, 212 | US8530652, 126 | US8530652, 74) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.60 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50097144 (CHEMBL3580963) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101548 (US8530494, 108 | US8530652, 127 | US8530652, 75) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.20 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101544 (US8530494, 105 | US8530652, 123 | US8530652, 71) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251114 (CHEMBL4076860) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50389111 (CHEMBL2064555) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PAK4 | J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101541 (US8530494, 104 | US8530652, 120 | US8530652, 68) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.70 | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251178 (CHEMBL4081464) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101504 (US8524699, 91 | US8524710, 82 | US8530652, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 7.20 | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101549 (US8530494, 109 | US8530652, 128 | US8530652, 76) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.30 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101543 (US8530494, 206 | US8530652, 122 | US8530652, 70) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.80 | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251098 (CHEMBL4097816) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101476 (US8524710, 53 | US8530652, 3 | US8530652, 47) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 11 | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251142 (CHEMBL4089338) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50097127 (CHEMBL3580949) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50389116 (CHEMBL2064561) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PAK4 | J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50389117 (CHEMBL2064562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PAK4 | J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101530 (US8530494, 29 | US8530494, 7 | US8530652, 57) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 14 | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101475 (US8524710, 52 | US8530652, 2 | US8530652, 46) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 14 | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101536 (CHEMBL3128043 | US8530494, 203 | US8530652, 114 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to N-terminal GST-tagged recombinant human PAK4 kinase domain expressed in Escherichia coli using KKRNRRLSVA as substrate preincubat... | J Med Chem 57: 1033-45 (2014) Article DOI: 10.1021/jm401768t BindingDB Entry DOI: 10.7270/Q2F47QNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101535 (US8530494, 104 | US8530652, 113 | US8530652, 62) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 15 | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101618 (US8530652, 114) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Chempartner Inc. Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged human recombinant PAK4 (300 to 591 amino acids) using peptide-7 substrate by pyruvate kinase and lactate dehydro... | J Med Chem 58: 5121-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00572 BindingDB Entry DOI: 10.7270/Q2DV1MN9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251140 (CHEMBL4059493) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251179 (CHEMBL4076708) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101515 (US8524699, 26 | US8530652, 42 | US8530670, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 16 | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101545 (US8530494, 107 | US8530652, 124 | US8530652, 72) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 16 | n/a | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251106 (CHEMBL4064068) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251137 (CHEMBL4101547) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251111 (CHEMBL4090101) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101524 (US8530652, 51 | US8530652, 96) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 18 | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101513 (US8524699, 18 | US8530652, 40 | US8530652, 85) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 18 | n/a | n/a | n/a | 98 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101536 (CHEMBL3128043 | US8530494, 203 | US8530652, 114 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | 20 | n/a | n/a | n/a | <3.90 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101504 (US8524699, 91 | US8524710, 82 | US8530652, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 20 | n/a | n/a | n/a | 103 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101507 (US8524710, 86 | US8530652, 34 | US8530652, 79) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 21 | n/a | n/a | n/a | 778 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101534 (US8530494, 202 | US8530652, 112 | US8530652, 61) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 22 | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101514 (US8524699, 22 | US8530652, 41 | US8530652, 86) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 24 | n/a | n/a | n/a | 147 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM101518 (US8524699, 46 | US8530652, 45 | US8530652, 90) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 25 | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent | Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a... | US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251197 (CHEMBL4063425) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50251113 (CHEMBL4077032) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP... | J Med Chem 61: 265-285 (2018) Article DOI: 10.1021/acs.jmedchem.7b01342 BindingDB Entry DOI: 10.7270/Q2BK1FSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human)) | BDBM50389113 (CHEMBL2064558) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PAK4 | J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W | |||||||||||
More data for this Ligand-Target Pair |
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