Compile Data Set for Download or QSAR

Found 25 hits for UniProtKB: P09660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524696 (CHEMBL4571835) Show SMILES CCN(C)C(=O)Oc1cc(cc2cccnc12)C(C)N(C)C Show InChI InChI=1S/C17H23N3O2/c1-6-20(5)17(21)22-15-11-14(12(2)19(3)4)10-13-8-7-9-18-16(13)15/h7-12H,6H2,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448370 (CHEMBL3120178) Show SMILES C[N+](C)(CCCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2cccc3cccc(C1=O)c23 |t:18| Show InChI InChI=1S/C33H46N4O4/c1-36(2,23-10-11-25-40-30-19-26-41-34-30)21-8-6-5-7-9-22-37(3,4)24-14-20-35-32(38)28-17-12-15-27-16-13-18-29(31(27)28)33(35)39/h12-13,15-18H,5-9,14,19-26H2,1-4H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524701 (CHEMBL4594074) Show SMILES CC(N1CCOCC1)c1cc(OC(=O)N2CCOCC2)c2ncccc2c1 Show InChI InChI=1S/C20H25N3O4/c1-15(22-5-9-25-10-6-22)17-13-16-3-2-4-21-19(16)18(14-17)27-20(24)23-7-11-26-12-8-23/h2-4,13-15H,5-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524708 (CHEMBL4459614) Show SMILES CC(N(C)C)c1cc(OC(=O)N2CCOCC2)c2ncccc2c1 Show InChI InChI=1S/C18H23N3O3/c1-13(20(2)3)15-11-14-5-4-6-19-17(14)16(12-15)24-18(22)21-7-9-23-10-8-21/h4-6,11-13H,7-10H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM11682 (2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...) Show SMILES CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C |r| Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448375 (CHEMBL3121479) Show SMILES C[N+](C)(CCCCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2cccc3cccc(C1=O)c23 |t:19| Show InChI InChI=1S/C34H48N4O4/c1-37(2,24-11-12-26-41-31-20-27-42-35-31)22-9-7-5-6-8-10-23-38(3,4)25-15-21-36-33(39)29-18-13-16-28-17-14-19-30(32(28)29)34(36)40/h13-14,16-19H,5-10,15,20-27H2,1-4H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448374 (CHEMBL3121478) Show SMILES C[N+](C)(CCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2cccc3cccc(C1=O)c23 |t:17| Show InChI InChI=1S/C32H44N4O4/c1-35(2,22-9-10-24-39-29-18-25-40-33-29)20-7-5-6-8-21-36(3,4)23-13-19-34-31(37)27-16-11-14-26-15-12-17-28(30(26)27)32(34)38/h11-12,14-17H,5-8,13,18-25H2,1-4H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524697 (CHEMBL4470950) Show SMILES CCN(CC)C(=O)Oc1cc(cc2cccnc12)C(C)N(C)C Show InChI InChI=1S/C18H25N3O2/c1-6-21(7-2)18(22)23-16-12-15(13(3)20(4)5)11-14-9-8-10-19-17(14)16/h8-13H,6-7H2,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524707 (CHEMBL4468053) Show SMILES CC(N(C)C)c1cc(OC(=O)N(C)C)c2ncccc2c1 Show InChI InChI=1S/C16H21N3O2/c1-11(18(2)3)13-9-12-7-6-8-17-15(12)14(10-13)21-16(20)19(4)5/h6-11H,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524705 (CHEMBL4452617) Show SMILES CCN(C)C(=O)Oc1cc(cc2cccnc12)C(C)N1CCCC1 Show InChI InChI=1S/C19H25N3O2/c1-4-21(3)19(23)24-17-13-16(14(2)22-10-5-6-11-22)12-15-8-7-9-20-18(15)17/h7-9,12-14H,4-6,10-11H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448369 (CHEMBL3121476) Show SMILES C[N+](C)(CCCCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2ccccc2C1=O |t:19| Show InChI InChI=1S/C30H46N4O4/c1-33(2,22-13-14-24-37-28-18-25-38-31-28)20-11-7-5-6-8-12-21-34(3,4)23-15-19-32-29(35)26-16-9-10-17-27(26)30(32)36/h9-10,16-17H,5-8,11-12,15,18-25H2,1-4H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524698 (CHEMBL4452986) Show SMILES CC(N(C)C)c1cc(OC(=O)N2CCCCC2)c2ncccc2c1 Show InChI InChI=1S/C19H25N3O2/c1-14(21(2)3)16-12-15-8-7-9-20-18(15)17(13-16)24-19(23)22-10-5-4-6-11-22/h7-9,12-14H,4-6,10-11H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448371 (CHEMBL3121480) Show SMILES C[N+](C)(CCCCCC[N+]1(C)CCC(CC1)N1C(=O)c2cccc3cccc(C1=O)c23)CC#CCOC1=NOCC1 |t:40,(26.01,-22.81,;26.76,-24.15,;27.54,-22.83,;25.23,-24.16,;24.45,-22.84,;22.91,-22.84,;22.13,-21.52,;20.59,-21.53,;19.81,-20.19,;18.27,-20.2,;19.03,-18.86,;17.49,-18.87,;15.95,-18.88,;15.19,-20.22,;15.97,-21.55,;17.51,-21.54,;13.65,-20.23,;12.88,-18.89,;13.64,-17.57,;11.35,-18.91,;10.58,-17.58,;9.05,-17.57,;8.28,-18.91,;9.04,-20.25,;8.28,-21.58,;9.06,-22.91,;10.59,-22.9,;11.35,-21.57,;12.9,-21.56,;13.67,-22.88,;10.58,-20.24,;27.53,-25.5,;29.07,-25.51,;30.61,-25.5,;32.15,-25.5,;32.92,-26.83,;34.46,-26.82,;35.38,-28.05,;36.84,-27.57,;36.83,-26.03,;35.37,-25.56,)| Show InChI InChI=1S/C33H44N4O4/c1-36(2,20-8-9-24-40-30-18-25-41-34-30)19-6-4-5-7-21-37(3)22-16-27(17-23-37)35-32(38)28-14-10-12-26-13-11-15-29(31(26)28)33(35)39/h10-15,27H,4-7,16-25H2,1-3H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524706 (CHEMBL4566337) Show SMILES CC(N(C)C)c1cc(OC(=O)N2CCCC2)c2ncccc2c1 Show InChI InChI=1S/C18H23N3O2/c1-13(20(2)3)15-11-14-7-6-8-19-17(14)16(12-15)23-18(22)21-9-4-5-10-21/h6-8,11-13H,4-5,9-10H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524703 (CHEMBL4443818) Show SMILES CCN(C)C(=O)Oc1cc(cc2cccnc12)C(C)N1CCCCC1 Show InChI InChI=1S/C20H27N3O2/c1-4-22(3)20(24)25-18-14-17(13-16-9-8-10-21-19(16)18)15(2)23-11-6-5-7-12-23/h8-10,13-15H,4-7,11-12H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448372 (CHEMBL3121475) Show SMILES C[N+](C)(CCCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2ccccc2C1=O |t:18| Show InChI InChI=1S/C29H44N4O4/c1-32(2,21-12-13-23-36-27-17-24-37-30-27)19-10-6-5-7-11-20-33(3,4)22-14-18-31-28(34)25-15-8-9-16-26(25)29(31)35/h8-9,15-16H,5-7,10-11,14,17-24H2,1-4H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524709 (CHEMBL4471688) Show SMILES CCN(C)C(C)c1cc(OC(=O)N(C)CC)c2ncccc2c1 Show InChI InChI=1S/C18H25N3O2/c1-6-20(4)13(3)15-11-14-9-8-10-19-17(14)16(12-15)23-18(22)21(5)7-2/h8-13H,6-7H2,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524702 (CHEMBL4517494) Show SMILES CCN(C)C(=O)Oc1cc(cc2cccnc12)C(C)N(CC)CC Show InChI InChI=1S/C19H27N3O2/c1-6-21(5)19(23)24-17-13-16(14(4)22(7-2)8-3)12-15-10-9-11-20-18(15)17/h9-14H,6-8H2,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50448376 (Naphmethonium) Show SMILES CC(C)(CN1C(=O)c2cccc3cccc(C1=O)c23)C[N+](C)(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C38H50N4O4/c1-38(2,26-40-36(45)31-20-13-16-28-17-14-21-32(33(28)31)37(40)46)27-42(5,6)24-12-8-7-11-23-41(3,4)25-15-22-39-34(43)29-18-9-10-19-30(29)35(39)44/h9-10,13-14,16-21H,7-8,11-12,15,22-27H2,1-6H3/q+2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay				Eur J Med Chem 75: 222-32 (2014) Article DOI: 10.1016/j.ejmech.2014.01.032 BindingDB Entry DOI: 10.7270/Q2K075RG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524700 (CHEMBL4535921) Show SMILES CC(N1CCOCC1)c1cc(OC(=O)N2CCCC2)c2ncccc2c1 Show InChI InChI=1S/C20H25N3O3/c1-15(22-9-11-25-12-10-22)17-13-16-5-4-6-21-19(16)18(14-17)26-20(24)23-7-2-3-8-23/h4-6,13-15H,2-3,7-12H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524704 (CHEMBL4446271) Show SMILES CCN(C)C(=O)Oc1cc(cc2cccnc12)C(C)N1CCN(C)CC1 Show InChI InChI=1S/C20H28N4O2/c1-5-23(4)20(25)26-18-14-17(13-16-7-6-8-21-19(16)18)15(2)24-11-9-22(3)10-12-24/h6-8,13-15H,5,9-12H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit epsilon (Rattus norvegicus)	BDBM50524699 (CHEMBL4557064) Show SMILES CC(N1CCOCC1)c1cc(OC(=O)N(C)C)c2ncccc2c1 Show InChI InChI=1S/C18H23N3O3/c1-13(21-7-9-23-10-8-21)15-11-14-5-4-6-19-17(14)16(12-15)24-18(22)20(2)3/h4-6,11-13H,7-10H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of rat brain cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by spectrophotometry				Eur J Med Chem 177: 247-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.051 BindingDB Entry DOI: 10.7270/Q24M980S
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/epsilon (Rattus norvegicus-RAT)	BDBM50206243 (CHEMBL3918431) Show SMILES C1N=C(Nc2cc3ccccc3cn2)O[C@]11CN2CCC1CC2 |r,wU:15.16,t:1,TLB:14:15:18.19:22.21,THB:0:15:18.19:22.21,(17.63,-8.02,;19,-7.33,;18.76,-5.81,;19.85,-4.72,;21.34,-5.11,;22.41,-4.02,;23.9,-4.41,;24.98,-3.32,;26.47,-3.71,;26.88,-5.2,;25.79,-6.3,;24.3,-5.9,;23.22,-7,;21.73,-6.6,;17.24,-5.56,;16.54,-6.93,;15.8,-8.21,;14.52,-7.62,;14.52,-5.71,;15.36,-4.63,;15.36,-6.25,;13.79,-6.93,;13,-8.11,)| Show InChI InChI=1S/C18H20N4O/c1-2-4-14-10-19-16(9-13(14)3-1)21-17-20-11-18(23-17)12-22-7-5-15(18)6-8-22/h1-4,9-10,15H,5-8,11-12H2,(H,19,20,21)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat alpha1beta1delta1epsilon nAChR expressed in HEK293 cells assessed as increase in Ca2+ flux by Fluo-4 AM dye based FLIPR assay				ACS Med Chem Lett 8: 366-371 (2017) Article DOI: 10.1021/acsmedchemlett.7b00032 BindingDB Entry DOI: 10.7270/Q2S46V8B
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/epsilon (Rattus norvegicus-RAT)	BDBM50235306 (CHEMBL4084621) Show SMILES C1N=C(Nc2cc(ncn2)-n2ccnc2)O[C@]11CN2CCC1CC2 |r,wD:16.18,t:1,TLB:0:16:19.20:23.22,THB:15:16:19.20:23.22,(31.2,-13.57,;31.65,-12.09,;30.38,-11.22,;30.34,-9.66,;31.67,-8.85,;31.64,-7.31,;32.95,-6.51,;34.32,-7.25,;34.35,-8.8,;33.03,-9.6,;32.91,-4.97,;31.64,-4.11,;32.08,-2.63,;33.62,-2.59,;34.13,-4.04,;29.15,-12.15,;29.66,-13.6,;30.52,-14.71,;28.75,-15.67,;28.49,-16.79,;27.69,-15.62,;28.18,-14.23,;26.95,-13.14,;27.24,-14.35,)| Show InChI InChI=1S/C16H19N7O/c1-4-22-5-2-12(1)16(9-22)8-18-15(24-16)21-13-7-14(20-10-19-13)23-6-3-17-11-23/h3,6-7,10-12H,1-2,4-5,8-9H2,(H,18,19,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat alpha1beta1delta1epsilon nAChR expressed in HEK293 cells assessed as increase in Ca2+ flux by Fluo-4 AM dye based FLIPR assay				ACS Med Chem Lett 8: 366-371 (2017) Article DOI: 10.1021/acsmedchemlett.7b00032 BindingDB Entry DOI: 10.7270/Q2S46V8B
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/epsilon (Rattus norvegicus-RAT)	BDBM50206243 (CHEMBL3918431) Show SMILES C1N=C(Nc2cc3ccccc3cn2)O[C@]11CN2CCC1CC2 |r,wU:15.16,t:1,TLB:14:15:18.19:22.21,THB:0:15:18.19:22.21,(17.63,-8.02,;19,-7.33,;18.76,-5.81,;19.85,-4.72,;21.34,-5.11,;22.41,-4.02,;23.9,-4.41,;24.98,-3.32,;26.47,-3.71,;26.88,-5.2,;25.79,-6.3,;24.3,-5.9,;23.22,-7,;21.73,-6.6,;17.24,-5.56,;16.54,-6.93,;15.8,-8.21,;14.52,-7.62,;14.52,-5.71,;15.36,-4.63,;15.36,-6.25,;13.79,-6.93,;13,-8.11,)| Show InChI InChI=1S/C18H20N4O/c1-2-4-14-10-19-16(9-13(14)3-1)21-17-20-11-18(23-17)12-22-7-5-15(18)6-8-22/h1-4,9-10,15H,5-8,11-12H2,(H,19,20,21)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat alpha1beta1deltaepsilon nAChR expressed in HEK293 cells for 2 mins by FLIPR assay				J Med Chem 59: 11171-11181 (2016) Article DOI: 10.1021/acs.jmedchem.6b01506 BindingDB Entry DOI: 10.7270/Q2NS0X2H
					More data for this Ligand-Target Pair