Compile Data Set for Download or QSAR

Found 126 hits of affinity data for UniProtKB/TrEMBL: P0A0J7   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368252 (CHEMBL4171147) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCc3cc(OC)c(OC)cc3C2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C33H38N2O6/c1-6-14-40-25-9-7-22(8-10-25)27-19-29(26-18-32(38-4)33(39-5)20-28(26)34-27)41-15-13-35-12-11-23-16-30(36-2)31(37-3)17-24(23)21-35/h7-10,16-20H,6,11-15,21H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368195 (CHEMBL4175014) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCc3cc(OC)c(OC)cc3C2)c2c(OC)cc(OC)cc2n1 Show InChI InChI=1S/C33H38N2O6/c1-6-14-40-25-9-7-22(8-10-25)27-20-32(33-28(34-27)18-26(36-2)19-31(33)39-5)41-15-13-35-12-11-23-16-29(37-3)30(38-4)17-24(23)21-35/h7-10,16-20H,6,11-15,21H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368266 (CHEMBL4172225) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCCC2)c2cc(OC)cc(OC)c2n1 Show InChI InChI=1S/C28H36N2O4/c1-4-16-33-22-11-9-21(10-12-22)25-20-26(34-17-15-30-13-7-5-6-8-14-30)24-18-23(31-2)19-27(32-3)28(24)29-25/h9-12,18-20H,4-8,13-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50211232 (CHEMBL3929187) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCNCc3ccc(Oc4nnnn4-c4ccccc4)c(OC)c3)cc12 Show InChI InChI=1S/C37H38N6O5/c1-4-46-36(44)35-26(2)42(25-27-12-7-5-8-13-27)32-18-17-30(23-31(32)35)47-21-11-20-38-24-28-16-19-33(34(22-28)45-3)48-37-39-40-41-43(37)29-14-9-6-10-15-29/h5-10,12-19,22-23,38H,4,11,20-21,24-25H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method				J Med Chem 60: 517-523 (2017) Article DOI: 10.1021/acs.jmedchem.6b01281 BindingDB Entry DOI: 10.7270/Q2D79DKR
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50245850 (CHEMBL4071003) Show SMILES C[C@@H]1O[C@@H](OC2C(Oc3cc(O)cc(O)c3C2=O)c2ccc(O)cc2)[C@H](OC(=O)\C=C\c2ccc(O)cc2)[C@H](O)[C@H]1OC(=O)\C=C\c1ccc(O)cc1 |r| Show InChI InChI=1S/C39H34O14/c1-20-35(51-30(45)16-6-21-2-10-24(40)11-3-21)34(48)38(52-31(46)17-7-22-4-12-25(41)13-5-22)39(49-20)53-37-33(47)32-28(44)18-27(43)19-29(32)50-36(37)23-8-14-26(42)15-9-23/h2-20,34-44,48H,1H3/b16-6+,17-7+/t20-,34+,35-,36?,37?,38+,39-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Palermo Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as reduction in ethidium bromide efflux by fluorescence assay				J Med Chem 60: 8268-8297 (2017) Article DOI: 10.1021/acs.jmedchem.7b00215 BindingDB Entry DOI: 10.7270/Q2RF5XDC
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50211228 (CHEMBL3956740) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCCNCc3ccc(Oc4nnnn4-c4ccccc4)c(OC)c3)cc12 Show InChI InChI=1S/C38H40N6O5/c1-4-47-37(45)36-27(2)43(26-28-13-7-5-8-14-28)33-19-18-31(24-32(33)36)48-22-12-11-21-39-25-29-17-20-34(35(23-29)46-3)49-38-40-41-42-44(38)30-15-9-6-10-16-30/h5-10,13-20,23-24,39H,4,11-12,21-22,25-26H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method				J Med Chem 60: 517-523 (2017) Article DOI: 10.1021/acs.jmedchem.6b01281 BindingDB Entry DOI: 10.7270/Q2D79DKR
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449611 (CHEMBL4177330) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OC(=O)c3ccccc3)ccc2n1 Show InChI InChI=1S/C32H34N2O4/c1-2-20-36-26-13-11-24(12-14-26)30-23-31(37-21-19-34-17-7-4-8-18-34)28-22-27(15-16-29(28)33-30)38-32(35)25-9-5-3-6-10-25/h3,5-6,9-16,22-23H,2,4,7-8,17-21H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368182 (CHEMBL4163342) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2c(OC)cc(OC)cc2n1 Show InChI InChI=1S/C26H34N2O4/c1-6-14-31-20-11-9-19(10-12-20)22-18-25(32-15-13-28(7-2)8-3)26-23(27-22)16-21(29-4)17-24(26)30-5/h9-12,16-18H,6-8,13-15H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449609 (CHEMBL4164053) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(O)ccc2n1 Show InChI InChI=1S/C25H30N2O3/c1-2-15-29-21-9-6-19(7-10-21)24-18-25(22-17-20(28)8-11-23(22)26-24)30-16-14-27-12-4-3-5-13-27/h6-11,17-18,28H,2-5,12-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449612 (CHEMBL4171010) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(OC(=O)c3ccccc3)ccc2n1 Show InChI InChI=1S/C31H34N2O4/c1-4-19-35-25-14-12-23(13-15-25)29-22-30(36-20-18-33(5-2)6-3)27-21-26(16-17-28(27)32-29)37-31(34)24-10-8-7-9-11-24/h7-17,21-22H,4-6,18-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368056 (CHEMBL4169284) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OC)cc(OC)c2n1 Show InChI InChI=1S/C27H34N2O4/c1-4-15-32-21-10-8-20(9-11-21)24-19-25(33-16-14-29-12-6-5-7-13-29)23-17-22(30-2)18-26(31-3)27(23)28-24/h8-11,17-19H,4-7,12-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368281 (CHEMBL4170066) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCc3cc(OC)c(OC)cc3C2)c2cc(OC)cc(OC)c2n1 Show InChI InChI=1S/C33H38N2O6/c1-6-14-40-25-9-7-22(8-10-25)28-20-29(27-18-26(36-2)19-32(39-5)33(27)34-28)41-15-13-35-12-11-23-16-30(37-3)31(38-4)17-24(23)21-35/h7-10,16-20H,6,11-15,21H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434974 (CHEMBL2385690) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCN(Cc3ccccc3)CC2)c2ccccc2n1 Show InChI InChI=1S/C31H35N3O2/c1-2-21-35-27-14-12-26(13-15-27)30-23-31(28-10-6-7-11-29(28)32-30)36-22-20-33-16-18-34(19-17-33)24-25-8-4-3-5-9-25/h3-15,23H,2,16-22,24H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50211230 (CHEMBL3948087) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCNCc3ccc(F)c(OC)c3)cc12 Show InChI InChI=1S/C30H33FN2O4/c1-4-36-30(34)29-21(2)33(20-22-9-6-5-7-10-22)27-14-12-24(18-25(27)29)37-16-8-15-32-19-23-11-13-26(31)28(17-23)35-3/h5-7,9-14,17-18,32H,4,8,15-16,19-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method				J Med Chem 60: 517-523 (2017) Article DOI: 10.1021/acs.jmedchem.6b01281 BindingDB Entry DOI: 10.7270/Q2D79DKR
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368050 (CHEMBL4164426) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C27H34N2O4/c1-4-15-32-21-10-8-20(9-11-21)23-18-25(33-16-14-29-12-6-5-7-13-29)22-17-26(30-2)27(31-3)19-24(22)28-23/h8-11,17-19H,4-7,12-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434973 (CHEMBL2385681) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCCN(C)C)c2ccccc2n1 Show InChI InChI=1S/C23H28N2O2/c1-4-15-26-19-12-10-18(11-13-19)22-17-23(27-16-7-14-25(2)3)20-8-5-6-9-21(20)24-22/h5-6,8-13,17H,4,7,14-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368053 (CHEMBL4161736) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2ccc(OC)cc2n1 Show InChI InChI=1S/C26H32N2O3/c1-3-16-30-21-9-7-20(8-10-21)24-19-26(31-17-15-28-13-5-4-6-14-28)23-12-11-22(29-2)18-25(23)27-24/h7-12,18-19H,3-6,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368289 (CHEMBL4162146) Show SMILES CCCOc1ccc(cc1)-c1cc(O)c2c(OC)cccc2n1 Show InChI InChI=1S/C19H19NO3/c1-3-11-23-14-9-7-13(8-10-14)16-12-17(21)19-15(20-16)5-4-6-18(19)22-2/h4-10,12H,3,11H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368055 (CHEMBL4175717) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C26H34N2O4/c1-6-14-31-20-11-9-19(10-12-20)22-17-24(32-15-13-28(7-2)8-3)21-16-25(29-4)26(30-5)18-23(21)27-22/h9-12,16-18H,6-8,13-15H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368119 (CHEMBL4162139) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OC)ccc2n1 Show InChI InChI=1S/C26H32N2O3/c1-3-16-30-21-9-7-20(8-10-21)25-19-26(31-17-15-28-13-5-4-6-14-28)23-18-22(29-2)11-12-24(23)27-25/h7-12,18-19H,3-6,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368171 (CHEMBL4176162) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCCN(C)C)c2ccc(OC)cc2n1 Show InChI InChI=1S/C24H30N2O3/c1-5-14-28-19-9-7-18(8-10-19)22-17-24(29-15-6-13-26(2)3)21-12-11-20(27-4)16-23(21)25-22/h7-12,16-17H,5-6,13-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153269 (CHEMBL3775575) Show SMILES CCOC(=O)c1c(C)n(Cc2cccc(c2)[N+]([O-])=O)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H33N3O5/c1-3-34-27(31)26-20(2)29(19-21-9-7-10-22(17-21)30(32)33)25-12-11-23(18-24(25)26)35-16-8-15-28-13-5-4-6-14-28/h7,9-12,17-18H,3-6,8,13-16,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449604 (CHEMBL4175374) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OCCCN3CCOCC3)ccc2n1 Show InChI InChI=1S/C32H43N3O4/c1-2-19-37-27-9-7-26(8-10-27)31-25-32(39-23-18-34-13-4-3-5-14-34)29-24-28(11-12-30(29)33-31)38-20-6-15-35-16-21-36-22-17-35/h7-12,24-25H,2-6,13-23H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368257 (CHEMBL4168943) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(OC)cc(OC)c2n1 Show InChI InChI=1S/C26H34N2O4/c1-6-14-31-20-11-9-19(10-12-20)23-18-24(32-15-13-28(7-2)8-3)22-16-21(29-4)17-25(30-5)26(22)27-23/h9-12,16-18H,6-8,13-15H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368126 (CHEMBL4172372) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2ccc(OC)cc2n1 Show InChI InChI=1S/C25H32N2O3/c1-5-15-29-20-10-8-19(9-11-20)23-18-25(30-16-14-27(6-2)7-3)22-13-12-21(28-4)17-24(22)26-23/h8-13,17-18H,5-7,14-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368158 (CHEMBL4174957) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCc3cc(OC)c(OC)cc3C2)c2ccc(OC)cc2n1 Show InChI InChI=1S/C32H36N2O5/c1-5-15-38-25-8-6-22(7-9-25)28-20-30(27-11-10-26(35-2)19-29(27)33-28)39-16-14-34-13-12-23-17-31(36-3)32(37-4)18-24(23)21-34/h6-11,17-20H,5,12-16,21H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368118 (CHEMBL4164737) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(OC)ccc2n1 Show InChI InChI=1S/C25H32N2O3/c1-5-15-29-20-10-8-19(9-11-20)24-18-25(30-16-14-27(6-2)7-3)22-17-21(28-4)12-13-23(22)26-24/h8-13,17-18H,5-7,14-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153316 (CHEMBL3775207) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2C)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C28H36N2O3/c1-4-32-28(31)27-22(3)30(20-23-12-7-6-11-21(23)2)26-14-13-24(19-25(26)27)33-18-10-17-29-15-8-5-9-16-29/h6-7,11-14,19H,4-5,8-10,15-18,20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153186 (CHEMBL3774520) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2F)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H33FN2O3/c1-3-32-27(31)26-20(2)30(19-21-10-5-6-11-24(21)28)25-13-12-22(18-23(25)26)33-17-9-16-29-14-7-4-8-15-29/h5-6,10-13,18H,3-4,7-9,14-17,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368143 (CHEMBL4167074) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCCC2)c2ccc(OC)cc2n1 Show InChI InChI=1S/C27H34N2O3/c1-3-17-31-22-10-8-21(9-11-22)25-20-27(24-13-12-23(30-2)19-26(24)28-25)32-18-16-29-14-6-4-5-7-15-29/h8-13,19-20H,3-7,14-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50211229 (CHEMBL3955315) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(O)CNCc3ccc(Oc4nnnn4-c4ccccc4)c(OC)c3)cc12 Show InChI InChI=1S/C37H38N6O6/c1-4-47-36(45)35-25(2)42(23-26-11-7-5-8-12-26)32-17-16-30(20-31(32)35)48-24-29(44)22-38-21-27-15-18-33(34(19-27)46-3)49-37-39-40-41-43(37)28-13-9-6-10-14-28/h5-20,29,38,44H,4,21-24H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method				J Med Chem 60: 517-523 (2017) Article DOI: 10.1021/acs.jmedchem.6b01281 BindingDB Entry DOI: 10.7270/Q2D79DKR
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153183 (CHEMBL3774548) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2OC)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C28H36N2O4/c1-4-33-28(31)27-21(2)30(20-22-11-6-7-12-26(22)32-3)25-14-13-23(19-24(25)27)34-18-10-17-29-15-8-5-9-16-29/h6-7,11-14,19H,4-5,8-10,15-18,20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449607 (CHEMBL4168471) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(OCCCN3CCOCC3)ccc2n1 Show InChI InChI=1S/C31H43N3O4/c1-4-18-36-26-10-8-25(9-11-26)30-24-31(38-22-17-33(5-2)6-3)28-23-27(12-13-29(28)32-30)37-19-7-14-34-15-20-35-21-16-34/h8-13,23-24H,4-7,14-22H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153314 (CHEMBL3774689) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(F)CN3CCCCC3)cc12 Show InChI InChI=1S/C27H33FN2O3/c1-3-32-27(31)26-20(2)30(17-21-10-6-4-7-11-21)25-13-12-23(16-24(25)26)33-19-22(28)18-29-14-8-5-9-15-29/h4,6-7,10-13,16,22H,3,5,8-9,14-15,17-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449605 (CHEMBL4167087) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2cc(OCCN(CC)CC)ccc2n1 Show InChI InChI=1S/C31H43N3O3/c1-4-20-35-26-12-10-25(11-13-26)30-24-31(37-22-19-34-16-8-7-9-17-34)28-23-27(14-15-29(28)32-30)36-21-18-33(5-2)6-3/h10-15,23-24H,4-9,16-22H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50368181 (CHEMBL4172781) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCNCC2)c2ccc(OC)cc2n1 Show InChI InChI=1S/C25H31N3O3/c1-3-15-30-20-6-4-19(5-7-20)23-18-25(31-16-14-28-12-10-26-11-13-28)22-9-8-21(29-2)17-24(22)27-23/h4-9,17-18,26H,3,10-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...				J Med Chem 61: 7827-7848 (2018) Article DOI: 10.1021/acs.jmedchem.8b00791 BindingDB Entry DOI: 10.7270/Q2D50QHG
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50449610 (CHEMBL4170494) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2cc(O)ccc2n1 Show InChI InChI=1S/C24H30N2O3/c1-4-14-28-20-10-7-18(8-11-20)23-17-24(29-15-13-26(5-2)6-3)21-16-19(27)9-12-22(21)25-23/h7-12,16-17,27H,4-6,13-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SA-1199B NorA assessed as reduction in EtBr efflux measured over 5 mins by fluorescence assay				Eur J Med Chem 155: 428-433 (2018) Article DOI: 10.1016/j.ejmech.2018.06.013 BindingDB Entry DOI: 10.7270/Q2XP77H5
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153284 (CHEMBL3775852) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(O)CN3CCCCC3)cc12 Show InChI InChI=1S/C27H34N2O4/c1-3-32-27(31)26-20(2)29(17-21-10-6-4-7-11-21)25-13-12-23(16-24(25)26)33-19-22(30)18-28-14-8-5-9-15-28/h4,6-7,10-13,16,22,30H,3,5,8-9,14-15,17-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153278 (CHEMBL3775105) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H34N2O3/c1-3-31-27(30)26-21(2)29(20-22-11-6-4-7-12-22)25-14-13-23(19-24(25)26)32-18-10-17-28-15-8-5-9-16-28/h4,6-7,11-14,19H,3,5,8-10,15-18,20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153278 (CHEMBL3775105) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H34N2O3/c1-3-31-27(30)26-21(2)29(20-22-11-6-4-7-12-22)25-14-13-23(19-24(25)26)32-18-10-17-28-15-8-5-9-16-28/h4,6-7,11-14,19H,3,5,8-10,15-18,20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method				J Med Chem 60: 517-523 (2017) Article DOI: 10.1021/acs.jmedchem.6b01281 BindingDB Entry DOI: 10.7270/Q2D79DKR
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153187 (CHEMBL3775401) Show SMILES CCOC(=O)c1c(C)n(Cc2cccc(F)c2)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H33FN2O3/c1-3-32-27(31)26-20(2)30(19-21-9-7-10-22(28)17-21)25-12-11-23(18-24(25)26)33-16-8-15-29-13-5-4-6-14-29/h7,9-12,17-18H,3-6,8,13-16,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153317 (CHEMBL3774886) Show SMILES CCOC(=O)c1c(C)n(Cc2cccc(C)c2)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C28H36N2O3/c1-4-32-28(31)27-22(3)30(20-23-11-8-10-21(2)18-23)26-13-12-24(19-25(26)27)33-17-9-16-29-14-6-5-7-15-29/h8,10-13,18-19H,4-7,9,14-17,20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153271 (CHEMBL3774968) Show SMILES CCOC(=O)Cc1c(C)n(Cc2ccccc2)c2ccc(OCCCN3CCCCCC3)cc12 Show InChI InChI=1S/C29H38N2O3/c1-3-33-29(32)21-26-23(2)31(22-24-12-7-6-8-13-24)28-15-14-25(20-27(26)28)34-19-11-18-30-16-9-4-5-10-17-30/h6-8,12-15,20H,3-5,9-11,16-19,21-22H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153268 (CHEMBL3775173) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2[N+]([O-])=O)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H33N3O5/c1-3-34-27(31)26-20(2)29(19-21-10-5-6-11-24(21)30(32)33)25-13-12-22(18-23(25)26)35-17-9-16-28-14-7-4-8-15-28/h5-6,10-13,18H,3-4,7-9,14-17,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434972 (CHEMBL2385684) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCCC2)c2ccccc2n1 Show InChI InChI=1S/C26H32N2O2/c1-2-18-29-22-13-11-21(12-14-22)25-20-26(23-9-5-6-10-24(23)27-25)30-19-17-28-15-7-3-4-8-16-28/h5-6,9-14,20H,2-4,7-8,15-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153270 (CHEMBL3775819) Show SMILES CCOC(=O)c1c(C)n(Cc2ccc(cc2)[N+]([O-])=O)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C27H33N3O5/c1-3-34-27(31)26-20(2)29(19-21-8-10-22(11-9-21)30(32)33)25-13-12-23(18-24(25)26)35-17-7-16-28-14-5-4-6-15-28/h8-13,18H,3-7,14-17,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153272 (CHEMBL3775722) Show SMILES Cc1cc2cc(OCCCN3CCCCC3)ccc2n1Cc1ccccc1 Show InChI InChI=1S/C24H30N2O/c1-20-17-22-18-23(27-16-8-15-25-13-6-3-7-14-25)11-12-24(22)26(20)19-21-9-4-2-5-10-21/h2,4-5,9-12,17-18H,3,6-8,13-16,19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153182 (CHEMBL3775053) Show SMILES CCOC(=O)c1c(C)n(Cc2ccc(C)cc2)c2ccc(OCCCN3CCCCC3)cc12 Show InChI InChI=1S/C28H36N2O3/c1-4-32-28(31)27-22(3)30(20-23-11-9-21(2)10-12-23)26-14-13-24(19-25(26)27)33-18-8-17-29-15-6-5-7-16-29/h9-14,19H,4-8,15-18,20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153283 (CHEMBL3774445) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCCN)cc12 Show InChI InChI=1S/C23H28N2O3/c1-3-27-23(26)22-17(2)25(16-18-9-5-4-6-10-18)21-12-11-19(15-20(21)22)28-14-8-7-13-24/h4-6,9-12,15H,3,7-8,13-14,16,24H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50153285 (CHEMBL3774995) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(O)CN3CCCCCC3)cc12 Show InChI InChI=1S/C28H36N2O4/c1-3-33-28(32)27-21(2)30(18-22-11-7-6-8-12-22)26-14-13-24(17-25(26)27)34-20-23(31)19-29-15-9-4-5-10-16-29/h6-8,11-14,17,23,31H,3-5,9-10,15-16,18-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) Article DOI: 10.1021/acs.jmedchem.5b01219 BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair

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