Found 91 hits of affinity data for UniProtKB/TrEMBL: P15086 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50530229
(CHEMBL4460840)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C26H35N2O6P/c1-18(2)14-23(27-19(3)29)25(30)28-24(16-21-12-8-5-9-13-21)35(33,34)17-22(26(31)32)15-20-10-6-4-7-11-20/h4-13,18,22-24H,14-17H2,1-3H3,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/t22-,23+,24-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet... |
J Med Chem 62: 1917-1931 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01465 BindingDB Entry DOI: 10.7270/Q2K077R9 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50530229
(CHEMBL4460840)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C26H35N2O6P/c1-18(2)14-23(27-19(3)29)25(30)28-24(16-21-12-8-5-9-13-21)35(33,34)17-22(26(31)32)15-20-10-6-4-7-11-20/h4-13,18,22-24H,14-17H2,1-3H3,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/t22-,23+,24-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet... |
J Med Chem 62: 1917-1931 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01465 BindingDB Entry DOI: 10.7270/Q2K077R9 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305346
((S)-2-(2-aminoethoxy)-3-(1-phenyl-1H-imidazol-4-yl...)Show InChI InChI=1S/C14H17N3O3/c15-6-7-20-13(14(18)19)8-11-9-17(10-16-11)12-4-2-1-3-5-12/h1-5,9-10,13H,6-8,15H2,(H,18,19)/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305348
((S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-...)Show InChI InChI=1S/C16H27N3O3/c17-7-9-22-15(16(20)21)10-14-11-19(12-18-14)8-6-13-4-2-1-3-5-13/h11-13,15H,1-10,17H2,(H,20,21)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305347
((S)-2-(2-aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc(C[C@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C18H25N3O3/c1-18(2,3)13-4-6-15(7-5-13)21-11-14(20-12-21)10-16(17(22)23)24-9-8-19/h4-7,11-12,16H,8-10,19H2,1-3H3,(H,22,23)/t16-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50226610
((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 206 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305345
((S)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...)Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 238 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305352
((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-phenyl-1H-i...)Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C15H19N3O3/c1-11(8-16)21-14(15(19)20)7-12-9-18(10-17-12)13-5-3-2-4-6-13/h2-6,9-11,14H,7-8,16H2,1H3,(H,19,20)/t11-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305351
((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-(pyridin-2-...)Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C14H18N4O3/c1-10(7-15)21-12(14(19)20)6-11-8-18(9-17-11)13-4-2-3-5-16-13/h2-5,8-10,12H,6-7,15H2,1H3,(H,19,20)/t10-,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 265 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305349
((+/-)-2-(2-aminoethoxy)-3-(1-butyl-1H-imidazol-4-y...)Show InChI InChI=1S/C12H21N3O3/c1-2-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13/h8-9,11H,2-7,13H2,1H3,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270378
(CHEMBL516131 | trans-1,1,3,3-tetraisopropyl-2-(3-(...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccc(cc1)[N+]([O-])=O)[Si](C)(C)C |r| Show InChI InChI=1S/C23H42N3O3PSSi/c1-16(2)24(17(3)4)30(31,25(18(5)6)19(7)8)23(32(9,10)11)22(29-23)20-12-14-21(15-13-20)26(27)28/h12-19,22H,1-11H3/t22-,23+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296412
(CHEMBL560871 | DL-guanidinoethylmercaptosuccinic a...)Show SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#16]-[#6](-[#6]-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50226606
((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)Show InChI InChI=1S/C11H20N4O2/c1-2-5-15-7-9(14-8-15)6-10(11(16)17)13-4-3-12/h7-8,10,13H,2-6,12H2,1H3,(H,16,17)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296414
(CHEMBL552336 | N-(3-chlorophenyl)-4-((5-(3-methoxy...)Show SMILES COc1cccc(CSc2nnc(Cc3csc(Nc4cccc(Cl)c4)n3)o2)c1 Show InChI InChI=1S/C20H17ClN4O2S2/c1-26-17-7-2-4-13(8-17)11-29-20-25-24-18(27-20)10-16-12-28-19(23-16)22-15-6-3-5-14(21)9-15/h2-9,12H,10-11H2,1H3,(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305350
((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...)Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270380
(CHEMBL515968 | trans-1,1,3,3-tetraisopropyl-2-((2S...)Show SMILES COc1ccc(cc1)[C@@H]1O[C@@]1([Si](C)(C)C)P(=S)(N(C(C)C)C(C)C)N(C(C)C)C(C)C |r| Show InChI InChI=1S/C24H45N2O2PSSi/c1-17(2)25(18(3)4)29(30,26(19(5)6)20(7)8)24(31(10,11)12)23(28-24)21-13-15-22(27-9)16-14-21/h13-20,23H,1-12H3/t23-,24+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270379
(CHEMBL515809 | trans-1,1,3,3-tetraisopropyl-2-((2S...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccc(cc1)C(F)(F)F)[Si](C)(C)C |r| Show InChI InChI=1S/C24H42F3N2OPSSi/c1-16(2)28(17(3)4)31(32,29(18(5)6)19(7)8)24(33(9,10)11)22(30-24)20-12-14-21(15-13-20)23(25,26)27/h12-19,22H,1-11H3/t22-,24+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296413
(CHEMBL551268 | N-benzyl-N-(4-phenylthiazol-2-yl)cy...)Show InChI InChI=1S/C20H18N2OS/c23-19(17-11-12-17)22(13-15-7-3-1-4-8-15)20-21-18(14-24-20)16-9-5-2-6-10-16/h1-10,14,17H,11-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296416
(CHEMBL563744 | methyl 2-(4-benzyl-5-(2-hydroxyphen...)Show InChI InChI=1S/C18H17N3O3S/c1-24-16(23)12-25-18-20-19-17(14-9-5-6-10-15(14)22)21(18)11-13-7-3-2-4-8-13/h2-10,22H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50575780
(CHEMBL4878039)Show SMILES Cn1cncc1-c1cc(F)ccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human pancreatic CPB incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometry |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02072 BindingDB Entry DOI: 10.7270/Q2SB49JM |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270386
(CHEMBL477076 | trans-(2RS,3RS)-3-(2-Thienyl)-2-tri...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1cccs1)[Si](C)(C)C |r| Show InChI InChI=1S/C21H41N2OPS2Si/c1-15(2)22(16(3)4)25(26,23(17(5)6)18(7)8)21(28(9,10)11)20(24-21)19-13-12-14-27-19/h12-18,20H,1-11H3/t20-,21+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296417
(CHEMBL561592 | isopropyl 2-(4-benzyl-5-(2-methoxyp...)Show InChI InChI=1S/C21H23N3O3S/c1-15(2)27-19(25)14-28-21-23-22-20(17-11-7-8-12-18(17)26-3)24(21)13-16-9-5-4-6-10-16/h4-12,15H,13-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296411
(1-(4-chlorophenyl)-2-(5-(2-hydroxyphenyl)-1,3,4-ox...)Show InChI InChI=1S/C16H11ClN2O3S/c17-11-7-5-10(6-8-11)14(21)9-23-16-19-18-15(22-16)12-3-1-2-4-13(12)20/h1-8,20H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM39191
(2-[4-Furan-2-ylmethyl-5-(4-hydroxy-phenyl)-4H-[1,2...)Show SMILES Oc1ccc(cc1)-c1nnc(SCC(=O)c2cccs2)n1Cc1ccco1 Show InChI InChI=1S/C19H15N3O3S2/c23-14-7-5-13(6-8-14)18-20-21-19(22(18)11-15-3-1-9-25-15)27-12-16(24)17-4-2-10-26-17/h1-10,23H,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270381
(CHEMBL478555 | trans-1,1,3,3-tetraisopropyl-2-((2S...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccc(C)cc1)[Si](C)(C)C |r| Show InChI InChI=1S/C24H45N2OPSSi/c1-17(2)25(18(3)4)28(29,26(19(5)6)20(7)8)24(30(10,11)12)23(27-24)22-15-13-21(9)14-16-22/h13-20,23H,1-12H3/t23-,24+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270387
(CHEMBL518749 | trans-(2RS,3RS)-3-(3-Thienyl)-2-tri...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccsc1)[Si](C)(C)C |r| Show InChI InChI=1S/C21H41N2OPS2Si/c1-15(2)22(16(3)4)25(26,23(17(5)6)18(7)8)21(28(9,10)11)20(24-21)19-12-13-27-14-19/h12-18,20H,1-11H3/t20-,21+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270385
(CHEMBL477075 | trans-(2RS,3RS)-3-(4-Pyridyl)-2-tri...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccncc1)[Si](C)(C)C |r| Show InChI InChI=1S/C22H42N3OPSSi/c1-16(2)24(17(3)4)27(28,25(18(5)6)19(7)8)22(29(9,10)11)21(26-22)20-12-14-23-15-13-20/h12-19,21H,1-11H3/t21-,22+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50121929
((phenylmethyl)butanedioic acid | 2-benzylbutanedio...)Show InChI InChI=1S/C11H12O4/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305353
((+/-)-2-(2-(methylamino)ethoxy)-3-(1-propyl-1H-imi...)Show InChI InChI=1S/C12H21N3O3/c1-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13-2/h8-9,11,13H,3-7H2,1-2H3,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50305354
((R)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...)Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human pancreatic carboxypeptidase B |
Bioorg Med Chem Lett 20: 92-6 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296420
(CHEMBL558714 | ethyl 2-(4-ethyl-5-((4-ethylphenoxy...)Show InChI InChI=1S/C20H29N3O3S/c1-6-15-9-11-16(12-10-15)26-13-17-21-22-20(23(17)7-2)27-18(14(4)5)19(24)25-8-3/h9-12,14,18H,6-8,13H2,1-5H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296421
(2-(4-benzyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-y...)Show InChI InChI=1S/C15H14N4OS2/c16-13(20)10-22-15-18-17-14(12-7-4-8-21-12)19(15)9-11-5-2-1-3-6-11/h1-8H,9-10H2,(H2,16,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296422
(2-(5-((4-chlorophenoxy)methyl)-1,3,4-oxadiazol-2-y...)Show InChI InChI=1S/C18H15ClN2O3S/c1-12-2-4-13(5-3-12)16(22)11-25-18-21-20-17(24-18)10-23-15-8-6-14(19)7-9-15/h2-9H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296424
(1-(2-fluorophenyl)-2-(5-o-tolyl-1,3,4-oxadiazol-2-...)Show InChI InChI=1S/C17H13FN2O2S/c1-11-6-2-3-7-12(11)16-19-20-17(22-16)23-10-15(21)13-8-4-5-9-14(13)18/h2-9H,10H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296418
(2-(6,9-dimethyl-5H-[1,2,4]triazino[5,6-b]indol-3-y...)Show SMILES Cc1ccc(C)c2c3nnc(SCC(=O)c4ccc(F)cc4)nc3[nH]c12 Show InChI InChI=1S/C19H15FN4OS/c1-10-3-4-11(2)16-15(10)17-18(21-16)22-19(24-23-17)26-9-14(25)12-5-7-13(20)8-6-12/h3-8H,9H2,1-2H3,(H,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270383
(CHEMBL477074 | trans-(2RS,3RS)-3-(2-Pyridyl)-2-tri...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccccn1)[Si](C)(C)C |r| Show InChI InChI=1S/C22H42N3OPSSi/c1-16(2)24(17(3)4)27(28,25(18(5)6)19(7)8)22(29(9,10)11)21(26-22)20-14-12-13-15-23-20/h12-19,21H,1-11H3/t21-,22+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296423
(CHEMBL551672 | N-(2-chlorobenzyl)-N-(furan-2-ylmet...)Show SMILES Cc1cc(ccc1-n1cnnn1)S(=O)(=O)N(Cc1ccco1)Cc1ccccc1Cl Show InChI InChI=1S/C20H18ClN5O3S/c1-15-11-18(8-9-20(15)26-14-22-23-24-26)30(27,28)25(13-17-6-4-10-29-17)12-16-5-2-3-7-19(16)21/h2-11,14H,12-13H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270392
(CHEMBL477269 | trans-(2RS,3RS)-3-(3-Furyl)-2-trime...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccoc1)[Si](C)(C)C |r| Show InChI InChI=1S/C21H41N2O2PSSi/c1-15(2)22(16(3)4)26(27,23(17(5)6)18(7)8)21(28(9,10)11)20(25-21)19-12-13-24-14-19/h12-18,20H,1-11H3/t20-,21+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270384
(CHEMBL515948 | trans-(2RS,3RS)-3-(3-Pyridyl)-2-tri...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1cccnc1)[Si](C)(C)C |r| Show InChI InChI=1S/C22H42N3OPSSi/c1-16(2)24(17(3)4)27(28,25(18(5)6)19(7)8)22(29(9,10)11)21(26-22)20-13-12-14-23-15-20/h12-19,21H,1-11H3/t21-,22+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296427
(2-(4-benzoylpiperidine-1-carbonyl)benzoic acid | C...)Show InChI InChI=1S/C20H19NO4/c22-18(14-6-2-1-3-7-14)15-10-12-21(13-11-15)19(23)16-8-4-5-9-17(16)20(24)25/h1-9,15H,10-13H2,(H,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296429
(2-(4-(2-methoxybenzyl)-5-(pyridin-4-yl)-4H-1,2,4-t...)Show SMILES COc1ccccc1Cn1c(SCC(=O)N2CCC(C)CC2)nnc1-c1ccncc1 Show InChI InChI=1S/C23H27N5O2S/c1-17-9-13-27(14-10-17)21(29)16-31-23-26-25-22(18-7-11-24-12-8-18)28(23)15-19-5-3-4-6-20(19)30-2/h3-8,11-12,17H,9-10,13-16H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296426
(CHEMBL563098 | N1-benzyl-N4-((tetrahydrofuran-2-yl...)Show SMILES O=S(=O)(NCc1ccccc1)c1ccc(cc1)S(=O)(=O)N(CC1CCCO1)Cc1cccs1 Show InChI InChI=1S/C23H26N2O5S3/c26-32(27,24-16-19-6-2-1-3-7-19)22-10-12-23(13-11-22)33(28,29)25(17-20-8-4-14-30-20)18-21-9-5-15-31-21/h1-3,5-7,9-13,15,20,24H,4,8,14,16-18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50270391
(CHEMBL514710 | trans-(2RS,3RS)-3-(2-Furyl)-2-trime...)Show SMILES CC(C)N(C(C)C)P(=S)(N(C(C)C)C(C)C)[C@@]1(O[C@H]1c1ccco1)[Si](C)(C)C |r| Show InChI InChI=1S/C21H41N2O2PSSi/c1-15(2)22(16(3)4)26(27,23(17(5)6)18(7)8)21(28(9,10)11)20(25-21)19-13-12-14-24-19/h12-18,20H,1-11H3/t20-,21+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human carboxypeptidase B |
Bioorg Med Chem 16: 4823-8 (2008)
Article DOI: 10.1016/j.bmc.2008.03.047 BindingDB Entry DOI: 10.7270/Q2CV4HJJ |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296430
(CHEMBL563306 | N-(3-methoxybenzyl)-3-methyl-N-(pyr...)Show SMILES COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1 Show InChI InChI=1S/C22H22N6O3S/c1-17-11-21(8-9-22(17)28-16-24-25-26-28)32(29,30)27(15-19-6-4-10-23-13-19)14-18-5-3-7-20(12-18)31-2/h3-13,16H,14-15H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296428
(2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-t...)Show SMILES CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H23N3O3S/c1-4-13-24(19(25)14-16-7-5-6-8-18(16)27-3)21-23-22-20(28-21)15-9-11-17(26-2)12-10-15/h5-12H,4,13-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296431
(3-methyl-N-(2-methylphenethyl)-4-(1H-tetrazol-1-yl...)Show InChI InChI=1S/C17H19N5O2S/c1-13-5-3-4-6-15(13)9-10-19-25(23,24)16-7-8-17(14(2)11-16)22-12-18-20-21-22/h3-8,11-12,19H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296434
(3-(5-(2-(2-fluorophenyl)-2-oxoethylthio)-1H-tetraz...)Show InChI InChI=1S/C16H11FN4O3S/c17-13-7-2-1-6-12(13)14(22)9-25-16-18-19-20-21(16)11-5-3-4-10(8-11)15(23)24/h1-8H,9H2,(H,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296415
(4-(5-(2-chlorobenzylthio)-1,3,4-oxadiazol-2-yl)-N-...)Show SMILES Clc1ccccc1CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)NCc1cccs1 Show InChI InChI=1S/C20H16ClN3O3S3/c21-18-6-2-1-4-15(18)13-29-20-24-23-19(27-20)14-7-9-17(10-8-14)30(25,26)22-12-16-5-3-11-28-16/h1-11,22H,12-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50279382
(3-((1R,2S)-2-(benzyloxycarbonylamino)cyclobutaneca...)Show SMILES OC(=O)CCNC(=O)[C@@H]1CC[C@@H]1NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C16H20N2O5/c19-14(20)8-9-17-15(21)12-6-7-13(12)18-16(22)23-10-11-4-2-1-3-5-11/h1-5,12-13H,6-10H2,(H,17,21)(H,18,22)(H,19,20)/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Autònoma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Saccharomyces cerevisiae by microtiter plate method |
Bioorg Med Chem 17: 3824-8 (2009)
Article DOI: 10.1016/j.bmc.2009.04.035 BindingDB Entry DOI: 10.7270/Q2S182DB |
More data for this Ligand-Target Pair | |
Carboxypeptidase B
(Homo sapiens (Human)) | BDBM50296433
(CHEMBL564664 | benzyl 2-(5-(2-fluorophenyl)-1,3,4-...)Show InChI InChI=1S/C17H13FN2O3S/c18-14-9-5-4-8-13(14)16-19-20-17(23-16)24-11-15(21)22-10-12-6-2-1-3-7-12/h1-9H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 6.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Aut£noma de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system |
Eur J Med Chem 44: 3266-71 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.034 BindingDB Entry DOI: 10.7270/Q26110C4 |
More data for this Ligand-Target Pair | |