Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Huntingtin (Homo sapiens (Human)) | BDBM50578375 (CHEMBL4875017) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50578380 (CHEMBL4878942) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50578376 (CHEMBL4863336) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50578377 (CHEMBL4847156) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50578378 (CHEMBL4867927) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50578379 (CHEMBL4859053) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of endogenous Huntingtin protein (unknown origin) incubated for overnight in presence of MW1/MAB2166 monoclonal antibody by ELISA-based MS... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00607 BindingDB Entry DOI: 10.7270/Q2TH8RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595435 (CHEMBL5179682) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595435 (CHEMBL5179682) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00875 BindingDB Entry DOI: 10.7270/Q2K35ZPC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM37533 ((2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylene...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Molecular Screening Center Curated by PubChem BioAssay | Assay Description The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2SQ8XSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM37535 (CHLORTETRACYCLINE HYDROCHLORIDE | MLS000069428 | S...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Molecular Screening Center Curated by PubChem BioAssay | Assay Description The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2SQ8XSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595433 (CHEMBL5195936) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595433 (CHEMBL5195936) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00875 BindingDB Entry DOI: 10.7270/Q2K35ZPC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595434 (CHEMBL5175104) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00875 BindingDB Entry DOI: 10.7270/Q2K35ZPC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM32023 ((2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylene...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Molecular Screening Center Curated by PubChem BioAssay | Assay Description The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2SQ8XSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50595434 (CHEMBL5175104) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM37536 ((2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methyl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Molecular Screening Center Curated by PubChem BioAssay | Assay Description The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2SQ8XSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM37534 ((2E,4R,12aR)-2-[amino(hydroxy)methylene]-4,7-bis(d...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Molecular Screening Center Curated by PubChem BioAssay | Assay Description The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2SQ8XSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96500 (MLS001157845 | N'-[(1E)-1-(1-cyclohexyl-2,4,6-trik...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96499 (MLS001158344 | N'-[(1Z)-1-(1-cyclohexyl-2,4,6-trik...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 452 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96534 (MLS003118514 | N-(5-chloranylthiophen-2-yl)sulfony...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 462 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96471 (3-[(2E)-2-(1-cyano-2-oxo-2-phenylethylidene)hydraz...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 561 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM64759 (3-(furan-2-carbonyl)-4-hydroxy-1-(6-methyl-1,3-ben...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 624 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM58741 (2-[3-hydroxy-2-keto-4-(5-methyl-2-furoyl)-5-(4-nit...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 636 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50257650 (4-(2-(6-chloroquinazolin-4-ylamino)ethyl)phenol | ...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Inhibition of Huntingtin protein aggregation by cell based assay | Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50256 ((5E)-1-butyl-5-[(E)-3-(2-furanyl)prop-2-enylidene]...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 721 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM48867 ((5Z)-2,6-diketo-4-methyl-5-[[5-(4-methyl-2-nitro-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 784 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96419 (6-chloranyl-N-[2-(2-chlorophenyl)ethyl]-5-methyl-7...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 796 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM53725 (MLS000035506 | N-[(5Z)-5-(4,5-dimethoxy-2-nitro-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 848 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM90877 (3-[(3-fluorobenzoyl)amino]-5-phenyl-2-thenoic acid...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 859 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM53935 (4-methyl-N-[(5Z)-4-oxidanylidene-5-(phenylmethylid...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 879 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM61891 (1-(6-Chloro-benzothiazol-2-yl)-4-(furan-2-carbonyl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 987 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96413 (6-(2-furanyl)-3-methyl-1-phenyl-4-pyrazolo[3,4-b]p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96462 (2-[(6E)-1-benzyl-2,4,5-triketo-6-p-anisylidene-7H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM70228 (3-[5-[(Z)-(5-azanylidene-7-oxidanylidene-3-propan-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM54149 (5-(3-thienyl)-3-({[4-(trifluoromethyl)phenyl]sulfo...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50257498 (4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Inhibition of Huntingtin protein aggregation by cell based assay | Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM46036 (2-[[3-(3-keto-1,2-benzothiazol-2-yl)phenyl]sulfony...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM46215 (2-[4-[[5-(4-chlorophenyl)-6-isopropoxycarbonyl-3-k...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50257649 (4-(2-(6-bromoquinazolin-4-ylamino)ethyl)phenol | C...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Inhibition of Huntingtin protein aggregation by cell based assay | Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96446 (MLS000391903 | SMR000260936 | cid_2318621) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM60895 (4-[3-[(5Z)-5-(2-furfurylidene)-4-keto-2-thioxo-thi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM75042 ((6Z)-5-imino-6-(1H-indol-3-ylmethylene)-3-(methyls...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM66209 (3-(1-benzofuran-2-carbonyl)-2-(3-chlorophenyl)-4-h...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50430741 (CHEMBL2333942) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of HD exon 1 fusion protein with 51 glutamine residues (unknown origin) aggregation expressed in Escherichia coli SURE after 16 hrs by Wes... | J Med Chem 56: 3121-47 (2013) Article DOI: 10.1021/jm3015926 BindingDB Entry DOI: 10.7270/Q23T9JKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96523 (Cefotaxime sodium salt | MLS002222330 | SMR0013072...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96424 (5-(butylcarbamoyl)-3-(naphthalen-1-ylsulfanylmethy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96519 (4-chloranyl-2-[2-[4-[(4-fluorophenyl)sulfonyl-meth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM50258237 (6-bromo-4-(4-methylpiperazin-1-yl)quinazoline | CH...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Inhibition of Huntingtin protein aggregation by cell based assay | Bioorg Med Chem Lett 19: 1715-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96417 (5-(4-methyl-1-naphthalenyl)-N-(4-methylphenyl)sulf...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Huntingtin (Homo sapiens (Human)) | BDBM96537 (1-[1-(4-chlorophenyl)cyclobutanecarbonyl]-2-methyl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair |
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