Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176988 (8-Chloro-1-(2,4-dichloro-phenyl)-1,3a,4,5,6,10b-he...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.000350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176980 (8-chloro-1-(2',4'-dichlorophenyl)-N-homopiperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.00100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176989 (8-chloro-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176979 (8-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.00520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176986 (8-bromo-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176990 (8-chloro-1-(2',4'-dichlorophenyl)-N-p-methoxylphen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176987 (8-methyl-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50172545 ((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8 | J Med Chem 48: 6386-92 (2005) Article DOI: 10.1021/jm050135l BindingDB Entry DOI: 10.7270/Q21V5FQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176976 (8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM239073 (US9416103, CP-55,940) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 0.370 | -53.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
The Board of Trustees of the University of Arkansas; The University of Kansas US Patent | Assay Description Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou... | US Patent US9416103 (2016) BindingDB Entry DOI: 10.7270/Q2HX1BKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50088439 (CHEMBL3526578) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.395 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysis | Drug Metab Dispos 40: 2174-84 (2012) Article DOI: 10.1124/dmd.112.047530 BindingDB Entry DOI: 10.7270/Q23R0VK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 420-5 (2001) BindingDB Entry DOI: 10.7270/Q2VH5MCT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50256379 (CHEMBL482356 | methyl 3-(4-chloronaphthalen-1-ylim...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd Curated by ChEMBL | Assay Description Binding affinity to mouse CB1 receptor | Bioorg Med Chem Lett 18: 6444-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.070 BindingDB Entry DOI: 10.7270/Q20V8CNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50060612 ((5Z,8Z,11Z,14Z)-2,16,16-Trimethyl-docosa-5,8,11,14...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix, Inc. Curated by ChEMBL | Assay Description Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) | J Med Chem 40: 3617-25 (1997) Article DOI: 10.1021/jm970212f BindingDB Entry DOI: 10.7270/Q2D50NNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50172545 ((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716A | J Med Chem 48: 6386-92 (2005) Article DOI: 10.1021/jm050135l BindingDB Entry DOI: 10.7270/Q21V5FQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50353747 (CHEMBL561013 | JWH-018) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas for Medical Sciences Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysis | Drug Metab Dispos 40: 2174-84 (2012) Article DOI: 10.1124/dmd.112.047530 BindingDB Entry DOI: 10.7270/Q23R0VK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysis | Eur J Med Chem 62: 256-69 (2013) Article DOI: 10.1016/j.ejmech.2012.12.056 BindingDB Entry DOI: 10.7270/Q2TQ62W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from CD1 mouse brain CB1 receptor | J Med Chem 49: 7502-12 (2006) Article DOI: 10.1021/jm060920d BindingDB Entry DOI: 10.7270/Q2057GRN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8 | J Med Chem 48: 6386-92 (2005) Article DOI: 10.1021/jm050135l BindingDB Entry DOI: 10.7270/Q21V5FQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM239078 (US9416103, TV-5-157) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Board of Trustees of the University of Arkansas; The University of Kansas US Patent | Assay Description A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai... | US Patent US9416103 (2016) BindingDB Entry DOI: 10.7270/Q2HX1BKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM239078 (US9416103, TV-5-157) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas Curated by ChEMBL | Assay Description Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq... | J Med Chem 56: 4537-50 (2013) Article DOI: 10.1021/jm400268b BindingDB Entry DOI: 10.7270/Q25M68M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in CD1 mouse brain membranes after 60 mins by liquid scintillation counting method | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176981 (8-chloro-1-(2',4'-dichlorophenyl)-N-p-chlorophenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463872 (US10787419, Serial # 72) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463870 (US10787419, Serial # 70) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50060615 ((5Z,8Z,11Z,14Z)-2,17-Dimethyl-docosa-5,8,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix, Inc. Curated by ChEMBL | Assay Description Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) | J Med Chem 40: 3617-25 (1997) Article DOI: 10.1021/jm970212f BindingDB Entry DOI: 10.7270/Q2D50NNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463781 (US10787419, Serial # 3E1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50193284 (CHEMBL3978981) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50072769 ((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain | J Med Chem 49: 5947-57 (2006) Article DOI: 10.1021/jm0603466 BindingDB Entry DOI: 10.7270/Q2DB82N5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176988 (8-Chloro-1-(2,4-dichloro-phenyl)-1,3a,4,5,6,10b-he...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50195527 (CHEMBL387001 | N-cycloheptyl-1-(p-fluorobenzyl)-7-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain | J Med Chem 49: 5947-57 (2006) Article DOI: 10.1021/jm0603466 BindingDB Entry DOI: 10.7270/Q2DB82N5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176985 (8-chloro-1-(2',4'-dichlorophenyl)-N-phenyl-1,4,5,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176980 (8-chloro-1-(2',4'-dichlorophenyl)-N-homopiperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscienze PharmaNess S.c.a r.l. Curated by ChEMBL | Assay Description Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometry | Eur J Med Chem 121: 194-208 (2016) Article DOI: 10.1016/j.ejmech.2016.05.011 BindingDB Entry DOI: 10.7270/Q2PR7XXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50060608 ((5Z,8Z,11Z,14Z)-2,16-Dimethyl-docosa-5,8,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix, Inc. Curated by ChEMBL | Assay Description Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) | J Med Chem 40: 3617-25 (1997) Article DOI: 10.1021/jm970212f BindingDB Entry DOI: 10.7270/Q2D50NNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from mouse brain CB1R expressed in CHOK1 cell membranes | J Med Chem 60: 1126-1141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01504 BindingDB Entry DOI: 10.7270/Q2WW7KXF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463825 (US10787419, Serial # 34) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50060617 ((5Z,8Z,11Z,14Z)-2-Methyl-icosa-5,8,11,14-tetraenoi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix, Inc. Curated by ChEMBL | Assay Description Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) | J Med Chem 40: 3617-25 (1997) Article DOI: 10.1021/jm970212f BindingDB Entry DOI: 10.7270/Q2D50NNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50230401 (CHEMBL4088079) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from mouse brain CB1R expressed in CHOK1 cell membranes | J Med Chem 60: 1126-1141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01504 BindingDB Entry DOI: 10.7270/Q2WW7KXF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50176991 (8-chloro-1-(2',4'-dichlorophenyl)-N-p-methylphenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain | J Med Chem 48: 7351-62 (2005) Article DOI: 10.1021/jm050317f BindingDB Entry DOI: 10.7270/Q2CF9PNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50213889 (3-[(Z)-5,6,7,8-tetrahydro-naphthalen-1-ylimino]-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co. Ltd Curated by ChEMBL | Assay Description Binding affinity to mouse CB1 receptor | Bioorg Med Chem Lett 17: 3925-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.099 BindingDB Entry DOI: 10.7270/Q2RX9BR5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463832 (US10787419, Serial # 41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50058508 (CHEMBL3331460) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Sassari Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from CD1 mouse brain (minus cerebellum) CB1 receptor by liquid scintillation counting | Eur J Med Chem 85: 747-57 (2014) Article DOI: 10.1016/j.ejmech.2014.08.042 BindingDB Entry DOI: 10.7270/Q2X068Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463793 (US10787419, Serial # 10E1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM463765 (US10787419, Compound 41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat... | US Patent US10787419 (2020) BindingDB Entry DOI: 10.7270/Q2HH6P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50213886 (3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5....) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co. Ltd Curated by ChEMBL | Assay Description Binding affinity to mouse CB1 receptor | Bioorg Med Chem Lett 17: 3925-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.099 BindingDB Entry DOI: 10.7270/Q2RX9BR5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50213886 (3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5....) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd Curated by ChEMBL | Assay Description Binding affinity to mouse CB1 receptor | Bioorg Med Chem Lett 18: 6444-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.070 BindingDB Entry DOI: 10.7270/Q20V8CNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50060605 ((5Z,8Z,11Z,14Z)-16,16-Dimethyl-docosa-5,8,11,14-te...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix, Inc. Curated by ChEMBL | Assay Description Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF) | J Med Chem 40: 3617-25 (1997) Article DOI: 10.1021/jm970212f BindingDB Entry DOI: 10.7270/Q2D50NNF | |||||||||||
More data for this Ligand-Target Pair |
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