Compile Data Set for Download or QSAR

Found 205 hits for UniProtKB: Q13555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.387	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human CAMK2G using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.656	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CAMK2G using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) Show SMILES CN[C@@H]1CC2OC([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C27H24N4O3/c1-28-16-11-19-30-17-9-5-4-8-14(17)21-22-15(12-29-26(22)32)20-13-7-3-6-10-18(13)31(23(20)24(21)30)27(34-19)25(16)33-2/h3-10,16,19,25,27-28H,11-12H2,1-2H3,(H,29,32)/t16-,19?,25-,27?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Temple University—Of The Commonwealth System Of Higher Education US Patent					Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...				US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50520464 (CHEMBL4556306) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCCC(=O)C1CCCCCC1)c1ccccc1 Show InChI InChI=1S/C24H31NO4S/c1-29-22-15-17-23(18-16-22)30(27,28)25(21-12-7-4-8-13-21)19-9-14-24(26)20-10-5-2-3-6-11-20/h4,7-8,12-13,15-18,20H,2-3,5-6,9-11,14,19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00302 BindingDB Entry DOI: 10.7270/Q20Z779V
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Spain S.A. Curated by ChEMBL					Assay Description Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbING				Bioorg Med Chem Lett 13: 3835-9 (2003) BindingDB Entry DOI: 10.7270/Q2Z89BTC
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Calcium/calmodulin-dependent protein kinase type II				Bioorg Med Chem Lett 13: 3049-53 (2003) BindingDB Entry DOI: 10.7270/Q2DR2TVT
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM2672 (3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Spain S.A. Curated by ChEMBL					Assay Description Inhibition of Cyclin E-cyclin-dependent kinase 2				Bioorg Med Chem Lett 13: 3835-9 (2003) BindingDB Entry DOI: 10.7270/Q2Z89BTC
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50217536 (CHEMBL2369378) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1-[#7+](-[#8-])=O)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1-[#7+](-[#8-])=O)-[#6](-[#6])-[#6])-[#6](-[#8])=O Show InChI InChI=1S/C80H126N24O27/c1-41(2)36-55(99-64(110)44(7)91-68(114)50(23-15-17-33-90-80(125)131-40-48-21-11-13-27-59(48)104(128)129)94-67(113)49(81)22-14-16-32-89-79(124)130-39-47-20-10-12-26-58(47)103(126)127)74(120)96-52(25-19-35-88-78(85)86)70(116)95-51(24-18-34-87-77(83)84)71(117)97-53(28-30-60(82)105)72(118)98-54(29-31-61(106)107)69(115)92-46(9)66(112)102-63(43(5)6)75(121)100-56(38-62(108)109)73(119)93-45(8)65(111)101-57(76(122)123)37-42(3)4/h10-13,20-21,26-27,41-46,49-57,63H,14-19,22-25,28-40,81H2,1-9H3,(H2,82,105)(H,89,124)(H,90,125)(H,91,114)(H,92,115)(H,93,119)(H,94,113)(H,95,116)(H,96,120)(H,97,117)(H,98,118)(H,99,110)(H,100,121)(H,101,111)(H,102,112)(H,106,107)(H,108,109)(H,122,123)(H4,83,84,87)(H4,85,86,88)/t44-,45-,46-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Osaka National Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against CaMKII				Bioorg Med Chem Lett 9: 1093-6 (1999) BindingDB Entry DOI: 10.7270/Q2JW8H34
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50217537 (CHEMBL385035) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1-[#7+](-[#8-])=O)-[#6](-[#6])-[#6])-[#6](-[#8])=O Show InChI InChI=1S/C69H116N22O22/c1-35(2)31-47(86-55(97)38(7)79-57(99)41(18-11-13-27-70)81-60(102)44(19-12-14-28-71)89-69(110)113-34-40-17-9-10-22-50(40)91(111)112)64(106)83-43(21-16-30-78-68(75)76)58(100)82-42(20-15-29-77-67(73)74)59(101)84-45(23-25-51(72)92)61(103)85-46(24-26-52(93)94)62(104)90-54(37(5)6)65(107)87-48(33-53(95)96)63(105)80-39(8)56(98)88-49(66(108)109)32-36(3)4/h9-10,17,22,35-39,41-49,54H,11-16,18-21,23-34,70-71H2,1-8H3,(H2,72,92)(H,79,99)(H,80,105)(H,81,102)(H,82,100)(H,83,106)(H,84,101)(H,85,103)(H,86,97)(H,87,107)(H,88,98)(H,89,110)(H,90,104)(H,93,94)(H,95,96)(H,108,109)(H4,73,74,77)(H4,75,76,78)/t38-,39-,41-,42-,43-,44-,45-,46-,47-,48-,49-,54-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Osaka National Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against CaMKII				Bioorg Med Chem Lett 9: 1093-6 (1999) BindingDB Entry DOI: 10.7270/Q2JW8H34
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458844 (US10759792, Compound I-12 | US11325908, Compound I...) Show SMILES COc1ccc2c(c1)[nH]c1nccc(-c3cccc(NCCN)c3)c21 Show InChI InChI=1S/C20H20N4O/c1-25-15-5-6-17-18(12-15)24-20-19(17)16(7-9-23-20)13-3-2-4-14(11-13)22-10-8-21/h2-7,9,11-12,22H,8,10,21H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458846 (US10759792, Compound I-13 | US11325908, Compound I...) Show SMILES Cc1ccc2[nH]c3nccc(-c4cccc(NCCN)c4)c3c2c1 Show InChI InChI=1S/C20H20N4/c1-13-5-6-18-17(11-13)19-16(7-9-23-20(19)24-18)14-3-2-4-15(12-14)22-10-8-21/h2-7,9,11-12,22H,8,10,21H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458847 (US10759792, Compound I-14 | US11325908, Compound I...) Show SMILES NCCNc1cccc(c1)-c1ccnc2[nH]c3ccc(Cl)cc3c12 Show InChI InChI=1S/C19H17ClN4/c20-13-4-5-17-16(11-13)18-15(6-8-23-19(18)24-17)12-2-1-3-14(10-12)22-9-7-21/h1-6,8,10-11,22H,7,9,21H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458823 (US10759792, Compound 9j | US11325908, Compound 9j) Show SMILES C1CN(CCN1)c1cccc(n1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C20H19N5/c1-2-5-17-14(4-1)19-15(8-9-22-20(19)24-17)16-6-3-7-18(23-16)25-12-10-21-11-13-25/h1-9,21H,10-13H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458833 (US10759792, Compound I-7 | US11325908, Compound I-...) Show SMILES NCCNc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C19H18N4/c20-9-11-21-14-5-3-4-13(12-14)15-8-10-22-19-18(15)16-6-1-2-7-17(16)23-19/h1-8,10,12,21H,9,11,20H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458835 (US10759792, Compound I-8 | US11325908, Compound I-...) Show SMILES NCCCNc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C20H20N4/c21-10-4-11-22-15-6-3-5-14(13-15)16-9-12-23-20-19(16)17-7-1-2-8-18(17)24-20/h1-3,5-9,12-13,22H,4,10-11,21H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458837 (US10759792, Compound I-9 | US11325908, Compound I-...) Show SMILES NCCOc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C19H17N3O/c20-9-11-23-14-5-3-4-13(12-14)15-8-10-21-19-18(15)16-6-1-2-7-17(16)22-19/h1-8,10,12H,9,11,20H2,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458840 (US10759792, Compound I-10 | US11325908, Compound I...) Show SMILES NCCCOc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C20H19N3O/c21-10-4-12-24-15-6-3-5-14(13-15)16-9-11-22-20-19(16)17-7-1-2-8-18(17)23-20/h1-3,5-9,11,13H,4,10,12,21H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458842 (US10759792, Compound I-11 | US11325908, Compound I...) Show SMILES Cc1ccc2c(c1)[nH]c1nccc(-c3cccc(NCCN)c3)c21 Show InChI InChI=1S/C20H20N4/c1-13-5-6-17-18(11-13)24-20-19(17)16(7-9-23-20)14-3-2-4-15(12-14)22-10-8-21/h2-7,9,11-12,22H,8,10,21H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM4552 (4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Center for Molecular Medicine of the Austrian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CAMK2G				Leukemia 23: 477-85 (2009) Article DOI: 10.1038/leu.2008.334 BindingDB Entry DOI: 10.7270/Q22Z15R6
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM2581 (3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...) Show SMILES O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8,22-23H,9H2,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Spain S.A. Curated by ChEMBL					Assay Description Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbING				Bioorg Med Chem Lett 13: 3835-9 (2003) BindingDB Entry DOI: 10.7270/Q2Z89BTC
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458831 (US10759792, Compound I-6 | US11325908, Compound I-...) Show SMILES Nc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C17H13N3/c18-12-5-3-4-11(10-12)13-8-9-19-17-16(13)14-6-1-2-7-15(14)20-17/h1-10H,18H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458822 (US10759792, Compound I-4 | US11325908, Compound I-...) Show SMILES NC(=N)Nc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C18H15N5/c19-18(20)22-12-5-3-4-11(10-12)13-8-9-21-17-16(13)14-6-1-2-7-15(14)23-17/h1-10H,(H,21,23)(H4,19,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458796 (US10759792, Compound I-1 | US11325908, Compound I-...) Show SMILES C1CN(CCN1)c1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C21H20N4/c1-2-7-19-18(6-1)20-17(8-9-23-21(20)24-19)15-4-3-5-16(14-15)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES CCN1CCOCCn2cc(C3=C(C(=O)NC3=O)c3cn(CCOCC1)c1ccccc31)c1ccccc21 |t:11| Show InChI InChI=1S/C30H32N4O4/c1-2-32-11-15-37-17-13-33-19-23(21-7-3-5-9-25(21)33)27-28(30(36)31-29(27)35)24-20-34(14-18-38-16-12-32)26-10-6-4-8-22(24)26/h3-10,19-20H,2,11-18H2,1H3,(H,31,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of PKC-beta II mediated IL-8 release from HEK293 cells by ELISA				Bioorg Med Chem Lett 13: 3049-53 (2003) BindingDB Entry DOI: 10.7270/Q2DR2TVT
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50520464 (CHEMBL4556306) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCCC(=O)C1CCCCCC1)c1ccccc1 Show InChI InChI=1S/C24H31NO4S/c1-29-22-15-17-23(18-16-22)30(27,28)25(21-12-7-4-8-13-21)19-9-14-24(26)20-10-5-2-3-6-11-20/h4,7-8,12-13,15-18,20H,2-3,5-6,9-11,14,19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01467 BindingDB Entry DOI: 10.7270/Q24Q801K
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50217535 (CHEMBL425458 | desLys-AIP) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#6](-[#6])-[#6])-[#6](-[#8])=O Show InChI InChI=1S/C60H98N18O19/c1-29(2)25-40(75-48(85)34(9)70-60(96)97-28-35-15-11-10-12-16-35)55(92)72-37(18-14-24-67-59(64)65)51(88)71-36(17-13-23-66-58(62)63)52(89)73-38(19-21-43(61)79)53(90)74-39(20-22-44(80)81)50(87)68-33(8)49(86)78-46(31(5)6)56(93)76-41(27-45(82)83)54(91)69-32(7)47(84)77-42(57(94)95)26-30(3)4/h10-12,15-16,29-34,36-42,46H,13-14,17-28H2,1-9H3,(H2,61,79)(H,68,87)(H,69,91)(H,70,96)(H,71,88)(H,72,92)(H,73,89)(H,74,90)(H,75,85)(H,76,93)(H,77,84)(H,78,86)(H,80,81)(H,82,83)(H,94,95)(H4,62,63,66)(H4,64,65,67)/t32-,33-,34-,36-,37-,38-,39-,40-,41-,42-,46-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka National Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against CaMKII				Bioorg Med Chem Lett 9: 1093-6 (1999) BindingDB Entry DOI: 10.7270/Q2JW8H34
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50217534 (CHEMBL413614) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1-[#7+](-[#8-])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1-[#7+](-[#8-])=O)-[#6](-[#6])-[#6])-[#6](-[#8])=O Show InChI InChI=1S/C77H121N23O26/c1-40(2)35-53(94-62(106)43(7)87-64(108)47(22-14-16-32-86-76(119)125-38-45-19-9-11-25-56(45)99(121)122)89-67(111)50(21-13-15-31-78)97-77(120)126-39-46-20-10-12-26-57(46)100(123)124)71(115)91-49(24-18-34-85-75(82)83)65(109)90-48(23-17-33-84-74(80)81)66(110)92-51(27-29-58(79)101)68(112)93-52(28-30-59(102)103)69(113)98-61(42(5)6)72(116)95-54(37-60(104)105)70(114)88-44(8)63(107)96-55(73(117)118)36-41(3)4/h9-12,19-20,25-26,40-44,47-55,61H,13-18,21-24,27-39,78H2,1-8H3,(H2,79,101)(H,86,119)(H,87,108)(H,88,114)(H,89,111)(H,90,109)(H,91,115)(H,92,110)(H,93,112)(H,94,106)(H,95,116)(H,96,107)(H,97,120)(H,98,113)(H,102,103)(H,104,105)(H,117,118)(H4,80,81,84)(H4,82,83,85)/t43-,44-,47-,48-,49-,50-,51-,52-,53-,54-,55-,61-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka National Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against CaMKII				Bioorg Med Chem Lett 9: 1093-6 (1999) BindingDB Entry DOI: 10.7270/Q2JW8H34
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128287 (3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...) Show SMILES CN1CCC(CC1)n1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccccc23)c2ccccc12 |t:11| Show InChI InChI=1S/C27H26N4O2/c1-29-13-11-17(12-14-29)31-16-21(19-8-4-6-10-23(19)31)25-24(26(32)28-27(25)33)20-15-30(2)22-9-5-3-7-18(20)22/h3-10,15-17H,11-14H2,1-2H3,(H,28,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128288 (3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCNCC3)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-19(17-6-2-4-8-21(17)29)23-24(26(32)28-25(23)31)20-15-30(16-10-12-27-13-11-16)22-9-5-3-7-18(20)22/h2-9,14-16,27H,10-13H2,1H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50563780 (CHEMBL4795714) Show SMILES Cl.CCCCCn1cc(nc1N)-c1ccccc1OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type human CAMK2gamma using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...				Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00023 BindingDB Entry DOI: 10.7270/Q2CR5Z3F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128282 (3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)n1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12 |t:11| Show InChI InChI=1S/C26H24N4O2/c1-29-12-10-16(11-13-29)30-15-20(18-7-3-5-9-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-4-2-6-17(19)21/h2-9,14-16,27H,10-13H2,1H3,(H,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458836 (US10759792, Compound 9n | US11325908, Compound 9n) Show SMILES C(C#Cc1ccnc2[nH]c3ccccc3c12)N1CCNCC1 Show InChI InChI=1S/C18H18N4/c1-2-6-16-15(5-1)17-14(7-8-20-18(17)21-16)4-3-11-22-12-9-19-10-13-22/h1-2,5-8,19H,9-13H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458843 (US10759792, Compound 8q | US11325908, Compound 8q) Show SMILES c1cc(c[nH]1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C15H11N3/c1-2-4-13-12(3-1)14-11(10-5-7-16-9-10)6-8-17-15(14)18-13/h1-9,16H,(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458829 (US10759792, Compound I-5 | US11325908, Compound I-...) Show SMILES NC(=N)NCc1cccc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C19H17N5/c20-19(21)23-11-12-4-3-5-13(10-12)14-8-9-22-18-17(14)15-6-1-2-7-16(15)24-18/h1-10H,11H2,(H,22,24)(H4,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458799 (US10759792, Compound 9a | US11325908, Compound 9a) Show SMILES C1CN(CCN1)c1cncc(c1)-c1ccnc2[nH]c3ccccc3c12 Show InChI InChI=1S/C20H19N5/c1-2-4-18-17(3-1)19-16(5-6-23-20(19)24-18)14-11-15(13-22-12-14)25-9-7-21-8-10-25/h1-6,11-13,21H,7-10H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128281 (18-dimethylaminomethyl-(18S)-17-oxa-4,14,21-triaza...) Show SMILES CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21 |t:10| Show InChI InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128280 (3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...) Show SMILES CCN1CCC(CC1)n1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccccc23)c2ccccc12 |t:12| Show InChI InChI=1S/C28H28N4O2/c1-3-31-14-12-18(13-15-31)32-17-22(20-9-5-7-11-24(20)32)26-25(27(33)29-28(26)34)21-16-30(2)23-10-6-4-8-19(21)23/h4-11,16-18H,3,12-15H2,1-2H3,(H,29,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128286 (3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...) Show SMILES CC(C)N1CCC(CC1)n1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccccc23)c2ccccc12 |t:13| Show InChI InChI=1S/C29H30N4O2/c1-18(2)32-14-12-19(13-15-32)33-17-23(21-9-5-7-11-25(21)33)27-26(28(34)30-29(27)35)22-16-31(3)24-10-6-4-8-20(22)24/h4-11,16-19H,12-15H2,1-3H3,(H,30,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 2				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50252338 (CHEMBL4090364) Show SMILES CCN(CC)CCCC(C)Nc1nc(\C=C\c2c(Cl)cc(Cl)cc2Cl)nc2ccc(N)cc12 Show InChI InChI=1S/C25H30Cl3N5/c1-4-33(5-2)12-6-7-16(3)30-25-20-15-18(29)8-10-23(20)31-24(32-25)11-9-19-21(27)13-17(26)14-22(19)28/h8-11,13-16H,4-7,12,29H2,1-3H3,(H,30,31,32)/b11-9+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, United States. Curated by ChEMBL					Assay Description Inhibition of CaMK2gamma (unknown origin)				Bioorg Med Chem 25: 2995-3005 (2017) Article DOI: 10.1016/j.bmc.2017.03.048 BindingDB Entry DOI: 10.7270/Q2VD71W7
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50128285 (3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCN(Cc4ccccn4)CC3)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinase				Bioorg Med Chem Lett 13: 1857-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V87
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50133064 (17,20,23-trioxa-4,12,14,26,28-pentaazahexacyclo[24...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCOCCn3cc2c2cccnc32)c2ncccc12 |c:5| Show InChI InChI=1S/C26H25N5O5/c32-25-21-19-15-30(23-17(19)3-1-5-27-23)7-9-34-11-13-36-14-12-35-10-8-31-16-20(22(21)26(33)29-25)18-4-2-6-28-24(18)31/h1-6,15-16H,7-14H2,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Calcium/calmodulin-dependent protein kinase II				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50401152 (CHEMBL2205766) Show SMILES CC(C)(C)NS(=O)(=O)c1cncc(c1)-c1ccn2nc(N)nc2c1 Show InChI InChI=1S/C15H18N6O2S/c1-15(2,3)20-24(22,23)12-6-11(8-17-9-12)10-4-5-21-13(7-10)18-14(16)19-21/h4-9,20H,1-3H3,(H2,16,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cellzome Ltd Curated by ChEMBL					Assay Description Inhibition of CAMK2G				Bioorg Med Chem Lett 22: 4613-8 (2012) Article DOI: 10.1016/j.bmcl.2012.05.090 BindingDB Entry DOI: 10.7270/Q2HQ412B
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM139539 (US8889696, 39) Show SMILES Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(Sc2ccc(F)cc2)c1=O Show InChI InChI=1S/C22H16FN5OS/c1-28-20-14(11-19(21(28)29)30-17-5-2-15(23)3-6-17)12-25-22(27-20)26-16-4-7-18-13(10-16)8-9-24-18/h2-12,24H,1H3,(H,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Temple University—Of The Commonwealth System Of Higher Education US Patent					Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...				US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50499634 (CHEMBL3741589) Show SMILES OC(=O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C1 Show InChI InChI=1S/C18H17Cl2NO3/c19-16-6-3-13(7-17(16)20)11-24-15-4-1-12(2-5-15)8-21-9-14(10-21)18(22)23/h1-7,14H,8-11H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of CaMK2gamma (unknown origin)				J Med Chem 58: 9154-70 (2015) Article DOI: 10.1021/acs.jmedchem.5b00928 BindingDB Entry DOI: 10.7270/Q2PZ5CV4
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50519662 (CHEMBL4438748) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1 Show InChI InChI=1S/C26H23N3O5/c1-29(2)20-8-6-17(7-9-20)26(32)28-19-5-3-4-18(14-19)27-25(31)16-34-21-10-11-22-23(30)12-13-33-24(22)15-21/h3-15H,16H2,1-2H3,(H,27,31)(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human CaMK2gamma (1 to 330 residues) using calmodulin as substrate incubated for 40 mins in presence of [gamma-33ATP] by ra...				J Med Chem 62: 10691-10710 (2019) Article DOI: 10.1021/acs.jmedchem.9b01143 BindingDB Entry DOI: 10.7270/Q2MC93FG
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM50135286 (CHEMBL3745885) Show SMILES Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F Show InChI InChI=1S/C22H15F2N5O3S/c1-29-20-13(9-19(21(29)30)33(31,32)18-5-2-14(23)10-16(18)24)11-26-22(28-20)27-15-3-4-17-12(8-15)6-7-25-17/h2-11,25H,1H3,(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human CAMK2gamma using [KKLNRTLSFAEPG] as substrate				Bioorg Med Chem 24: 521-44 (2016) Article DOI: 10.1016/j.bmc.2015.11.045 BindingDB Entry DOI: 10.7270/Q24Q7WT8
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50133059 (17,20,23-trioxa-4,12,14,26-tetraazahexacyclo[24.6....) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCOCCn3cc2c2cccnc32)c2ccccc12 |c:5| Show InChI InChI=1S/C27H26N4O5/c32-26-23-20-16-30(22-6-2-1-4-18(20)22)8-10-34-12-14-36-15-13-35-11-9-31-17-21(24(23)27(33)29-26)19-5-3-7-28-25(19)31/h1-7,16-17H,8-15H2,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Calcium/calmodulin-dependent protein kinase II				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50133057 (17,20,23-trioxa-4,14,26-triazahexacyclo[24.6.1.17,...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCOCCn3cc2c2ccccc32)c2ccccc12 |c:5| Show InChI InChI=1S/C28H27N3O5/c32-27-25-21-17-30(23-7-3-1-5-19(21)23)9-11-34-13-15-36-16-14-35-12-10-31-18-22(26(25)28(33)29-27)20-6-2-4-8-24(20)31/h1-8,17-18H,9-16H2,(H,29,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Calcium/calmodulin-dependent protein kinase II				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50133058 (17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCOCCOCCn3cc2c2cccnc32)c2ncccc12 |c:5| Show InChI InChI=1S/C28H29N5O6/c34-27-23-21-17-32(25-19(21)3-1-5-29-25)7-9-36-11-13-38-15-16-39-14-12-37-10-8-33-18-22(24(23)28(35)31-27)20-4-2-6-30-26(20)33/h1-6,17-18H,7-16H2,(H,31,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Calcium/calmodulin-dependent protein kinase II				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair

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