Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynureninase (Homo sapiens (Human)) | BDBM50069730 (2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Compound was tested for the binding affinity against bacterial kynureninase | Bioorg Med Chem Lett 8: 133-8 (1999) BindingDB Entry DOI: 10.7270/Q2639NXW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50288256 ((R)-2-Amino-3-(2-amino-benzenesulfonyl)-propionic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibition of human kynureninase | J Med Chem 52: 389-96 (2009) Article DOI: 10.1021/jm8010806 BindingDB Entry DOI: 10.7270/Q2DZ0860 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from human | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50288255 (2-ammonio-4-(2-ammoniophenyl)-4-oxo-(2S)-butanoate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article | 4.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50288257 ((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from bacterial cells | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50288254 (2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem | Article | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50265459 (3-Hydroxyhippuric acid | CHEMBL447627) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibition of human kynureninase | J Med Chem 52: 389-96 (2009) Article DOI: 10.1021/jm8010806 BindingDB Entry DOI: 10.7270/Q2DZ0860 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50288258 ((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 8.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence | Bioorg Med Chem Lett 6: 2643-2646 (1996) Article DOI: 10.1016/S0960-894X(96)00483-0 BindingDB Entry DOI: 10.7270/Q2HM5903 | |||||||||||
More data for this Ligand-Target Pair |