Compile Data Set for Download or QSAR

Found 531 hits of affinity data for UniProtKB/TrEMBL: Q9H7Z6   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM43339 (4-amino-1-naphthalenol;hydrochloride | 4-amino-1-n...) Show SMILES Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H9NO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as...				Eur J Med Chem 136: 480-486 (2017) Article DOI: 10.1016/j.ejmech.2017.05.015 BindingDB Entry DOI: 10.7270/Q20Z75S9
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580678 (US11492346, Example 18) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12)C(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580661 (US11492346, Example 1) Show SMILES CCc1ccc(OC)c(c1)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580684 (US11492346, Example 24) Show SMILES COc1cc(cc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580675 (US11492346, Example 15) Show SMILES CCc1cc(c(OC)cc1OC)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580677 (US11492346, Example 17) Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580750 (US11492346, Example 92) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(Br)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580710 (US11492346, Example 50) Show SMILES CCOc1cc(C)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580674 (US11492346, Example 14) Show SMILES COc1cc(OC)c(c(OC)c1)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580751 (US11492346, Example 93) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580680 (US11492346, Example 20) Show SMILES COc1cc2CCCCc2cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580669 (US11492346, Example 9 | US11492346, Example 90 | U...) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580687 (US11492346, Example 27) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(C)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580721 (US11492346, Example 61) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cccc4c(C)ccnc34)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580707 (US11492346, Example 47) Show SMILES COc1cc(C)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580665 (US11492346, Example 5) Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580669 (US11492346, Example 9 | US11492346, Example 90 | U...) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580669 (US11492346, Example 9 | US11492346, Example 90 | U...) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580669 (US11492346, Example 9 | US11492346, Example 90 | U...) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580681 (US11492346, Example 21) Show SMILES COc1ccc2CCCCc2c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580705 (US11492346, Example 45) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccccc3CO)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580679 (US11492346, Example 19) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580689 (US11492346, Example 29) Show SMILES COc1cc2CCCc2cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580672 (US11492346, Example 12) Show SMILES COCc1ccc(OC)c(c1)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580711 (US11492346, Example 51) Show SMILES CCOc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580731 (US11492346, Example 71) Show SMILES COc1cc(Cl)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580755 (US11492346, Example 97) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580676 (US11492346, Example 16) Show SMILES COc1ccc(OC(F)(F)F)cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580683 (US11492346, Example 23) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3nccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM43339 (4-amino-1-naphthalenol;hydrochloride | 4-amino-1-n...) Show SMILES Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H9NO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as...				Eur J Med Chem 136: 480-486 (2017) Article DOI: 10.1016/j.ejmech.2017.05.015 BindingDB Entry DOI: 10.7270/Q20Z75S9
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580668 (US11492346, Example 8) Show SMILES COc1cc(Br)cc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580730 (US11492346, Example 70) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cccc(C)c3F)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580688 (US11492346, Example 28) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580739 (US11492346, Example 79) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccc(C)c(F)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580752 (US11492346, Example 94) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(F)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580753 (US11492346, Example 95) Show SMILES CCc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3c(OC)cccc3OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580671 (US11492346, Example 11) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC3CC3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580733 (US11492346, Example 73) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3c(C)ccc4cccnc34)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580666 (US11492346, Example 13 | US11492346, Example 6) Show SMILES COc1cccc(F)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580667 (US11492346, Example 7) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cc(F)cn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580757 (US11492346, Example 100) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3ccc(C)n3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580685 (US11492346, Example 25) Show SMILES CCOc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3c(OC)cccc3OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580732 (US11492346, Example 72) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccc(C)c(C)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580725 (US11492346, Example 65) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccc(C)cc3F)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580744 (US11492346, Example 84) Show SMILES COc1ccc(cc1C)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580754 (US11492346, Example 96) Show SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(C3CC3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580738 (US11492346, Example 78) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cc(C)c(F)c(C)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580737 (US11492346, Example 77) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccc(cc3)C(F)F)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580736 (US11492346, Example 76) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cccc(C)c3C#N)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM580735 (US11492346, Example 75) Show SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cc(C)cc(F)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...				Citation and Details BindingDB Entry DOI: 10.7270/Q23J3HT5
					More data for this Ligand-Target Pair

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