Compile Data Set for Download or QSAR

Found 64 hits of affinity data for UniProtKB/TrEMBL: Q9P0G3   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-14 (Homo sapiens (Human))	BDBM50124906 (CHEMBL3623776) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSSC[C@]([H])(NC(=O)[C@@]([H])(NC(=O)CNC(=O)[C@H](CC(N)=O)NC2=O)[C@@H](C)O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1 |r| Show InChI InChI=1S/C60H97N19O19S2/c1-7-27(3)43-54(93)71-35-25-99-100-26-36(72-55(94)45(29(5)81)73-42(85)23-66-47(86)32(21-40(61)83)68-52(91)37-14-10-18-77(37)57(96)33(22-41(62)84)69-50(35)89)51(90)76-46(30(6)82)56(95)67-31(13-9-17-65-60(63)64)48(87)70-34(24-80)49(88)75-44(28(4)8-2)59(98)79-20-12-16-39(79)58(97)78-19-11-15-38(78)53(92)74-43/h27-39,43-46,80-82H,7-26H2,1-6H3,(H2,61,83)(H2,62,84)(H,66,86)(H,67,95)(H,68,91)(H,69,89)(H,70,87)(H,71,93)(H,72,94)(H,73,85)(H,74,92)(H,75,88)(H,76,90)(H4,63,64,65)/t27-,28-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,43-,44-,45-,46-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Queensland University of Technology Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry method				J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50125021 (CHEMBL3623779) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSSC[C@]([H])(NC(=O)[C@@]([H])(NC(=O)CNC(=O)[C@H](CC(N)=O)NC2=O)[C@@H](C)O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1 |r| Show InChI InChI=1S/C58H92N20O20S2/c1-5-25(2)42-52(93)71-33-23-99-100-24-34(72-53(94)43(26(3)80)73-41(85)21-65-45(86)29(18-38(59)82)67-50(91)35-11-7-15-76(35)55(96)30(19-39(60)83)69-48(33)89)49(90)75-44(27(4)81)54(95)66-28(10-6-14-64-58(62)63)46(87)70-32(22-79)47(88)68-31(20-40(61)84)56(97)78-17-9-13-37(78)57(98)77-16-8-12-36(77)51(92)74-42/h25-37,42-44,79-81H,5-24H2,1-4H3,(H2,59,82)(H2,60,83)(H2,61,84)(H,65,86)(H,66,95)(H,67,91)(H,68,88)(H,69,89)(H,70,87)(H,71,93)(H,72,94)(H,73,85)(H,74,92)(H,75,90)(H4,62,63,64)/t25-,26+,27+,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,42-,43-,44-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Queensland University of Technology Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry method				J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50125044 (CHEMBL3623790) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSSC[C@]([H])(NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CNC(=O)[C@H](CC(N)=O)NC2=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1 |r| Show InChI InChI=1S/C69H104N20O17S2/c1-7-34(4)53-64(102)78-40(18-12-22-74-69(72)73)57(95)81-44(31-90)59(97)86-55(36(6)9-3)68(106)89-25-15-21-49(89)67(105)88-24-14-20-48(88)63(101)85-54(35(5)8-2)65(103)83-45-32-107-108-33-46(61(99)84-53)82-58(96)41(26-37-29-75-39-17-11-10-16-38(37)39)77-52(93)30-76-56(94)42(27-50(70)91)79-62(100)47-19-13-23-87(47)66(104)43(28-51(71)92)80-60(45)98/h10-11,16-17,29,34-36,40-49,53-55,75,90H,7-9,12-15,18-28,30-33H2,1-6H3,(H2,70,91)(H2,71,92)(H,76,94)(H,77,93)(H,78,102)(H,79,100)(H,80,98)(H,81,95)(H,82,96)(H,83,103)(H,84,99)(H,85,101)(H,86,97)(H4,72,73,74)/t34-,35-,36-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,53-,54-,55-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Queensland University of Technology Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry method				J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50125028 (CHEMBL3623791) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSSC[C@]([H])(NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CNC(=O)[C@H](CC(N)=O)NC2=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1 |r| Show InChI InChI=1S/C69H105N21O17S2/c1-5-35(3)54-64(103)79-40(18-11-23-75-69(73)74)57(96)83-45(32-91)59(98)80-41(17-9-10-22-70)66(105)90-26-14-21-50(90)68(107)89-25-13-20-49(89)63(102)87-55(36(4)6-2)65(104)85-46-33-108-109-34-47(61(100)86-54)84-58(97)42(27-37-30-76-39-16-8-7-15-38(37)39)78-53(94)31-77-56(95)43(28-51(71)92)81-62(101)48-19-12-24-88(48)67(106)44(29-52(72)93)82-60(46)99/h7-8,15-16,30,35-36,40-50,54-55,76,91H,5-6,9-14,17-29,31-34,70H2,1-4H3,(H2,71,92)(H2,72,93)(H,77,95)(H,78,94)(H,79,103)(H,80,98)(H,81,101)(H,82,99)(H,83,96)(H,84,97)(H,85,104)(H,86,100)(H,87,102)(H4,73,74,75)/t35-,36-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,54-,55-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Queensland University of Technology Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry method				J Med Chem 58: 8257-68 (2015) Article DOI: 10.1021/acs.jmedchem.5b01148 BindingDB Entry DOI: 10.7270/Q2PR7XSJ
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50513781 (CHEMBL4466351) Show SMILES NC(=O)C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N2 |r| Show InChI InChI=1S/C72H95N19O21S2/c73-55(95)31-45-59(100)78-33-57(97)79-44(28-38-14-18-40(93)19-15-38)62(103)88-50-35-113-114-36-51(66(107)85-47(29-37-8-2-1-3-9-37)69(110)89-25-5-11-52(89)68(109)83-45)87-61(102)43(22-23-58(98)99)81-67(108)53-12-6-26-90(53)71(112)54-13-7-27-91(54)70(111)48(30-39-16-20-41(94)21-17-39)84-64(105)49(34-92)86-60(101)42(10-4-24-77-72(75)76)80-63(104)46(32-56(74)96)82-65(50)106/h1-3,8-9,14-21,42-54,92-94H,4-7,10-13,22-36H2,(H2,73,95)(H2,74,96)(H,78,100)(H,79,97)(H,80,104)(H,81,108)(H,82,106)(H,83,109)(H,84,105)(H,85,107)(H,86,101)(H,87,102)(H,88,103)(H,98,99)(H4,75,76,77)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of recombinant human KLK14 expressed in Spodoptera frugiperda Sf9 cells using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins ...				J Med Chem 62: 3696-3706 (2019) Article DOI: 10.1021/acs.jmedchem.9b00211 BindingDB Entry DOI: 10.7270/Q2639T2R
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50513780 (CHEMBL4456106) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N2)[C@@H](C)O)[C@@H](C)CC |r| Show InChI InChI=1S/C67H105N19O17S2/c1-6-35(3)51-62(99)80-44-33-104-105-34-45(79-55(92)39(20-13-25-72-67(70)71)74-50(90)31-73-54(91)41(30-49(69)89)76-60(97)46-21-14-26-84(46)64(101)42(77-58(44)95)29-38-17-9-8-10-18-38)59(96)83-53(37(5)88)63(100)75-40(19-11-12-24-68)56(93)78-43(32-87)57(94)82-52(36(4)7-2)66(103)86-28-16-23-48(86)65(102)85-27-15-22-47(85)61(98)81-51/h8-10,17-18,35-37,39-48,51-53,87-88H,6-7,11-16,19-34,68H2,1-5H3,(H2,69,89)(H,73,91)(H,74,90)(H,75,100)(H,76,97)(H,77,95)(H,78,93)(H,79,92)(H,80,99)(H,81,98)(H,82,94)(H,83,96)(H4,70,71,72)/t35-,36-,37+,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,51-,52-,53-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of recombinant KLK14 (unknown origin) expressed in Spodoptera frugiperda Sf9 cells using pNA peptide as susbtrate measured every 10 secs f...				J Med Chem 62: 3696-3706 (2019) Article DOI: 10.1021/acs.jmedchem.9b00211 BindingDB Entry DOI: 10.7270/Q2639T2R
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50513783 (CHEMBL4456620) Show SMILES NC(=O)C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)CNC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N2 |r| Show InChI InChI=1S/C74H96N20O19S2/c75-58(97)33-49-61(101)80-35-59(98)82-47(29-40-11-3-1-4-12-40)64(104)91-53-37-114-115-38-54(68(108)88-50(30-41-13-5-2-6-14-41)71(111)92-26-8-16-55(92)70(110)86-49)90-63(103)46(23-24-60(99)100)84-69(109)56-17-9-27-93(56)73(113)57-18-10-28-94(57)72(112)51(31-42-19-21-44(96)22-20-42)87-66(106)52(36-95)89-62(102)45(15-7-25-79-74(76)77)83-65(105)48(85-67(53)107)32-43-34-78-39-81-43/h1-6,11-14,19-22,34,39,45-57,95-96H,7-10,15-18,23-33,35-38H2,(H2,75,97)(H,78,81)(H,80,101)(H,82,98)(H,83,105)(H,84,109)(H,85,107)(H,86,110)(H,87,106)(H,88,108)(H,89,102)(H,90,103)(H,91,104)(H,99,100)(H4,76,77,79)/t45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of recombinant human KLK14 expressed in Spodoptera frugiperda Sf9 cells using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins ...				J Med Chem 62: 3696-3706 (2019) Article DOI: 10.1021/acs.jmedchem.9b00211 BindingDB Entry DOI: 10.7270/Q2639T2R
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113065 (US9695194, 2) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1Cl Show InChI InChI=1S/C17H14ClNO4/c1-3-22-15-8-11-13(9-14(15)21-2)19-16(23-17(11)20)10-6-4-5-7-12(10)18/h4-9H,3H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	100	-41.6	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113060 (US9695194, 1) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1SC Show InChI InChI=1S/C18H17NO4S/c1-4-22-15-9-12-13(10-14(15)21-2)19-17(23-18(12)20)11-7-5-6-8-16(11)24-3/h5-10H,4H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	100	-41.6	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50513785 (CHEMBL4575658) Show SMILES NC(=O)C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)CNC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N2 |r| Show InChI InChI=1S/C76H97N21O19S2/c77-60(100)32-51-63(104)83-35-61(101)85-49(28-40-10-2-1-3-11-40)66(107)94-55-37-117-118-38-56(70(111)91-53(30-42-33-82-46-13-5-4-12-45(42)46)74(115)95-25-7-15-57(95)72(113)89-51)93-65(106)48(22-23-62(102)103)87-71(112)58-16-8-26-96(58)75(116)59-17-9-27-97(59)73(114)52(29-41-18-20-44(99)21-19-41)90-68(109)54(36-98)92-64(105)47(14-6-24-81-76(78)79)86-67(108)50(88-69(55)110)31-43-34-80-39-84-43/h1-5,10-13,18-21,33-34,39,47-59,82,98-99H,6-9,14-17,22-32,35-38H2,(H2,77,100)(H,80,84)(H,83,104)(H,85,101)(H,86,108)(H,87,112)(H,88,110)(H,89,113)(H,90,109)(H,91,111)(H,92,105)(H,93,106)(H,94,107)(H,102,103)(H4,78,79,81)/t47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of recombinant human KLK14 expressed in Spodoptera frugiperda Sf9 cells using Boc-QAR-MCA as susbtrate measured every 60 secs for 10 mins ...				J Med Chem 62: 3696-3706 (2019) Article DOI: 10.1021/acs.jmedchem.9b00211 BindingDB Entry DOI: 10.7270/Q2639T2R
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113069 (US9695194, 5) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1OC Show InChI InChI=1S/C18H17NO5/c1-4-23-16-9-12-13(10-15(16)22-3)19-17(24-18(12)20)11-7-5-6-8-14(11)21-2/h5-10H,4H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	300	-38.7	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113067 (US9695194, 3) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccc(OC)cc1OC Show InChI InChI=1S/C19H19NO6/c1-5-25-17-9-13-14(10-16(17)24-4)20-18(26-19(13)21)12-7-6-11(22-2)8-15(12)23-3/h6-10H,5H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	500	-37.4	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113299 (US9695194, 15) Show SMILES COC1CC(OC)=CC=C1c1nc2cc3OCCOc3cc2c(=O)o1 |c:6,8| Show InChI InChI=1S/C18H17NO6/c1-21-10-3-4-11(14(7-10)22-2)17-19-13-9-16-15(23-5-6-24-16)8-12(13)18(20)25-17/h3-4,8-9,14H,5-7H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	-37.4	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113296 (US9695194, 13) Show SMILES COc1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1 Show InChI InChI=1S/C17H13NO5/c1-20-13-5-3-2-4-10(13)16-18-12-9-15-14(21-6-7-22-15)8-11(12)17(19)23-16/h2-5,8-9H,6-7H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	800	-36.2	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113068 (US9695194, 4) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C18H17NO6S/c1-4-24-15-9-12-13(10-14(15)23-2)19-17(25-18(12)20)11-7-5-6-8-16(11)26(3,21)22/h5-10H,4H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.00E+3	-35.6	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113301 (US9695194, 17) Show SMILES COc1ccc(c(OC)c1)-c1nc2cc(OC)c(OC)cc2c(=O)o1 Show InChI InChI=1S/C18H17NO6/c1-21-10-5-6-11(14(7-10)22-2)17-19-13-9-16(24-4)15(23-3)8-12(13)18(20)25-17/h5-9H,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.10E+3	-35.4	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113295 (US9695194, 12) Show SMILES COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1SC Show InChI InChI=1S/C17H15NO4S/c1-20-13-8-11-12(9-14(13)21-2)18-16(22-17(11)19)10-6-4-5-7-15(10)23-3/h4-9H,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.10E+3	-35.4	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113300 (US9695194, 16) Show SMILES Clc1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1 Show InChI InChI=1S/C16H10ClNO4/c17-11-4-2-1-3-9(11)15-18-12-8-14-13(20-5-6-21-14)7-10(12)16(19)22-15/h1-4,7-8H,5-6H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.30E+3	-34.9	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113119 (US9695194, 6) Show SMILES COc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1 Show InChI InChI=1S/C18H15NO5/c1-21-14-6-3-2-5-11(14)17-19-13-10-16-15(22-7-4-8-23-16)9-12(13)18(20)24-17/h2-3,5-6,9-10H,4,7-8H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.40E+3	-34.8	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113297 (US9695194, 14) Show SMILES CS(=O)(=O)c1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1 Show InChI InChI=1S/C17H13NO6S/c1-25(20,21)15-5-3-2-4-10(15)16-18-12-9-14-13(22-6-7-23-14)8-11(12)17(19)24-16/h2-5,8-9H,6-7H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.50E+3	-34.6	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113292 (US9695194, 9) Show SMILES CSc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1 Show InChI InChI=1S/C18H15NO4S/c1-24-16-6-3-2-5-11(16)17-19-13-10-15-14(21-7-4-8-22-15)9-12(13)18(20)23-17/h2-3,5-6,9-10H,4,7-8H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.50E+3	-34.6	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50256262 (CHEMBL4070056) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H]2CSCc3cc(CSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(O)=O)cc(CSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(N)=N)C(=O)N2)c3)C(C)C |r| Show InChI InChI=1S/C114H161N29O28S3/c1-10-62(4)94-107(166)136-85(101(160)124-63(5)108(167)141(9)53-91(151)140(8)52-90(150)139(7)51-89(149)126-75(22-16-39-122-113(117)118)95(154)128-77(111(170)171)23-17-40-123-114(119)120)59-173-56-70-43-69-44-71(45-70)57-174-60-86(103(162)137-93(61(2)3)106(165)131-79(47-67-27-33-73(147)34-28-67)98(157)132-82(49-68-29-35-74(148)36-30-68)109(168)142-41-18-24-87(142)104(163)130-80(50-92(152)153)99(158)138-94)135-96(155)76(21-14-15-38-121-112(115)116)127-97(156)78(46-66-25-31-72(146)32-26-66)129-105(164)88-37-42-143(88)110(169)81(48-65-19-12-11-13-20-65)133-100(159)83(54-144)134-102(161)84(58-172-55-69)125-64(6)145/h11-13,19-20,25-36,43-45,61-63,75-88,93-94,144,146-148H,10,14-18,21-24,37-42,46-60H2,1-9H3,(H,124,160)(H,125,145)(H,126,149)(H,127,156)(H,128,154)(H,129,164)(H,130,163)(H,131,165)(H,132,157)(H,133,159)(H,134,161)(H,135,155)(H,136,166)(H,137,162)(H,138,158)(H,152,153)(H,170,171)(H4,115,116,121)(H4,117,118,122)(H4,119,120,123)/t62-,63-,75+,76-,77+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88?,93-,94-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10His-tagged KLK14 (19 to 248 residues) expressed in mouse NS0 cells using fluorogenic Boc-VPR-AMC peptide...				J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50289001 (2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazi...) Show SMILES COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1I Show InChI InChI=1S/C16H12INO4/c1-20-13-7-10-12(8-14(13)21-2)18-15(22-16(10)19)9-5-3-4-6-11(9)17/h3-8H,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	2.10E+3	-33.7	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113283 (US9695194, 8) Show SMILES COc1ccc(c(OC)c1)-c1nc2cc3OCCCOc3cc2c(=O)o1 Show InChI InChI=1S/C19H17NO6/c1-22-11-4-5-12(15(8-11)23-2)18-20-14-10-17-16(24-6-3-7-25-17)9-13(14)19(21)26-18/h4-5,8-10H,3,6-7H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	2.30E+3	-33.5	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113248 (US9695194, 7) Show SMILES Clc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1 Show InChI InChI=1S/C17H12ClNO4/c18-12-5-2-1-4-10(12)16-19-13-9-15-14(21-6-3-7-22-15)8-11(13)17(20)23-16/h1-2,4-5,8-9H,3,6-7H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	2.70E+3	-33.1	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113293 (US9695194, 10) Show SMILES CS(=O)(=O)c1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1 Show InChI InChI=1S/C18H15NO6S/c1-26(21,22)16-6-3-2-5-11(16)17-19-13-10-15-14(23-7-4-8-24-15)9-12(13)18(20)25-17/h2-3,5-6,9-10H,4,7-8H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	5.20E+3	-31.4	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113294 (US9695194, 11) Show SMILES CC(C)c1ccc(-c2nc3cc4OCCCOc4cc3c(=O)o2)c(c1)C(C)C Show InChI InChI=1S/C23H25NO4/c1-13(2)15-6-7-16(17(10-15)14(3)4)22-24-19-12-21-20(26-8-5-9-27-21)11-18(19)23(25)28-22/h6-7,10-14H,5,8-9H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	>1.00E+4	>-29.7	n/a	n/a	n/a	n/a	n/a	8.0	37
SIXERA PHARMA AB US Patent					Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...				US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50507483 (CHEMBL4530379) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]4CSSC[C@H](NC(=O)[C@H](Cc5ccc(O)cc5)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N4)NC(=O)[C@@H](NC3=O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N2 |r| Show InChI InChI=1S/C136H220N46O44S6/c1-10-66(7)105-130(223)170-77(43-64(3)4)118(211)164-72(23-12-15-35-137)113(206)162-73(24-13-16-36-138)116(209)174-87-59-228-229-60-88-125(218)161-71(26-18-38-147-134(141)142)108(201)150-50-97(190)158-79(45-94(140)187)109(202)151-51-96(189)157-78(44-69-31-33-70(186)34-32-69)119(212)173-86-58-227-231-62-90(176-121(214)82(48-103(198)199)169-123(216)85(57-185)171-120(213)81(47-102(196)197)168-115(208)76(28-20-40-149-136(145)146)163-114(207)75(165-124(87)217)27-19-39-148-135(143)144)132(225)181-41-21-29-92(181)127(220)155-49-95(188)156-68(9)107(200)172-89(126(219)180-106(67(8)11-2)131(224)175-88)61-230-232-63-91(133(226)182-42-22-30-93(182)128(221)166-74(117(210)179-105)25-14-17-37-139)177-129(222)104(65(5)6)178-100(193)54-152-110(203)80(46-101(194)195)167-122(215)84(56-184)160-99(192)52-153-111(204)83(55-183)159-98(191)53-154-112(86)205/h31-34,64-68,71-93,104-106,183-186H,10-30,35-63,137-139H2,1-9H3,(H2,140,187)(H,150,201)(H,151,202)(H,152,203)(H,153,204)(H,154,205)(H,155,220)(H,156,188)(H,157,189)(H,158,190)(H,159,191)(H,160,192)(H,161,218)(H,162,206)(H,163,207)(H,164,211)(H,165,217)(H,166,221)(H,167,215)(H,168,208)(H,169,216)(H,170,223)(H,171,213)(H,172,200)(H,173,212)(H,174,209)(H,175,224)(H,176,214)(H,177,222)(H,178,193)(H,179,210)(H,180,219)(H,194,195)(H,196,197)(H,198,199)(H4,141,142,147)(H4,143,144,148)(H4,145,146,149)/t66-,67-,68-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,104-,105-,106-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in sf9 cells using Ac-YANR-pNA as substrate preincubated for 30 mins followed by substrate addition an...				ACS Med Chem Lett 9: 1258-1262 (2018) Article DOI: 10.1021/acsmedchemlett.8b00422 BindingDB Entry DOI: 10.7270/Q2Q81HCD
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50507481 (CHEMBL4564063) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]4CSSC[C@H](NC(=O)[C@H](Cc5ccc(O)cc5)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N4)NC(=O)[C@@H](NC3=O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 |r| Show InChI InChI=1S/C142H224N50O46S6/c1-8-68(5)110-136(236)182-81(44-67(3)4)124(224)176-75(24-13-15-37-143)118(218)173-76(25-14-16-38-144)121(221)186-92-62-240-242-64-94-133(233)172-74(26-17-39-155-139(147)148)113(213)161-54-104(203)169-84(47-99(146)198)114(214)162-55-103(202)168-83(46-72-31-33-73(196)34-32-72)125(225)185-91-61-239-244-66-96(189-128(228)87(50-109(210)211)181-130(230)90(60-195)183-127(227)86(49-108(208)209)180-120(220)78(28-19-41-157-141(151)152)174-119(219)77(177-131(92)231)27-18-40-156-140(149)150)138(238)192-43-21-30-97(192)135(235)165-53-101(200)166-70(7)112(212)184-95(134(234)191-111(69(6)9-2)137(237)188-94)65-243-241-63-93(132(232)178-80(35-36-98(145)197)122(222)175-79(123(223)190-110)29-20-42-158-142(153)154)187-126(226)82(45-71-22-11-10-12-23-71)167-102(201)52-159-100(199)51-160-115(215)85(48-107(206)207)179-129(229)89(59-194)171-106(205)56-163-116(216)88(58-193)170-105(204)57-164-117(91)217/h10-12,22-23,31-34,67-70,74-97,110-111,193-196H,8-9,13-21,24-30,35-66,143-144H2,1-7H3,(H2,145,197)(H2,146,198)(H,159,199)(H,160,215)(H,161,213)(H,162,214)(H,163,216)(H,164,217)(H,165,235)(H,166,200)(H,167,201)(H,168,202)(H,169,203)(H,170,204)(H,171,205)(H,172,233)(H,173,218)(H,174,219)(H,175,222)(H,176,224)(H,177,231)(H,178,232)(H,179,229)(H,180,220)(H,181,230)(H,182,236)(H,183,227)(H,184,212)(H,185,225)(H,186,221)(H,187,226)(H,188,237)(H,189,228)(H,190,223)(H,191,234)(H,206,207)(H,208,209)(H,210,211)(H4,147,148,155)(H4,149,150,156)(H4,151,152,157)(H4,153,154,158)/t68-,69-,70-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,110-,111-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in sf9 cells using Ac-YANR-pNA as substrate preincubated for 30 mins followed by substrate addition an...				ACS Med Chem Lett 9: 1258-1262 (2018) Article DOI: 10.1021/acsmedchemlett.8b00422 BindingDB Entry DOI: 10.7270/Q2Q81HCD
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50507482 (CHEMBL4531700) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]4CSSC[C@H](NC(=O)[C@H](Cc5ccc(O)cc5)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N4)NC(=O)[C@@H](NC3=O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 |r| Show InChI InChI=1S/C138H208N44O50S6/c1-8-63(5)109-135(230)172-76(39-62(3)4)123(218)166-71(26-31-93(140)187)118(213)165-75(30-35-97(144)191)121(216)176-87-57-234-236-59-89-132(227)162-69(19-13-14-36-139)112(207)151-49-103(197)159-79(42-98(145)192)113(208)152-50-102(196)158-78(41-67-22-24-68(186)25-23-67)124(219)175-86-56-233-238-61-91(179-127(222)82(45-108(204)205)171-129(224)85(55-185)173-126(221)81(44-107(202)203)170-120(215)74(29-34-96(143)190)164-119(214)73(168-130(87)225)28-33-95(142)189)137(232)182-38-16-21-92(182)134(229)155-48-100(194)156-65(7)111(206)174-90(133(228)181-110(64(6)9-2)136(231)178-89)60-237-235-58-88(131(226)167-72(27-32-94(141)188)117(212)163-70(122(217)180-109)20-15-37-148-138(146)147)177-125(220)77(40-66-17-11-10-12-18-66)157-101(195)47-149-99(193)46-150-114(209)80(43-106(200)201)169-128(223)84(54-184)161-105(199)51-153-115(210)83(53-183)160-104(198)52-154-116(86)211/h10-12,17-18,22-25,62-65,69-92,109-110,183-186H,8-9,13-16,19-21,26-61,139H2,1-7H3,(H2,140,187)(H2,141,188)(H2,142,189)(H2,143,190)(H2,144,191)(H2,145,192)(H,149,193)(H,150,209)(H,151,207)(H,152,208)(H,153,210)(H,154,211)(H,155,229)(H,156,194)(H,157,195)(H,158,196)(H,159,197)(H,160,198)(H,161,199)(H,162,227)(H,163,212)(H,164,214)(H,165,213)(H,166,218)(H,167,226)(H,168,225)(H,169,223)(H,170,215)(H,171,224)(H,172,230)(H,173,221)(H,174,206)(H,175,219)(H,176,216)(H,177,220)(H,178,231)(H,179,222)(H,180,217)(H,181,228)(H,200,201)(H,202,203)(H,204,205)(H4,146,147,148)/t63-,64-,65-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,109-,110-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in sf9 cells using Ac-YANR-pNA as substrate preincubated for 30 mins followed by substrate addition an...				ACS Med Chem Lett 9: 1258-1262 (2018) Article DOI: 10.1021/acsmedchemlett.8b00422 BindingDB Entry DOI: 10.7270/Q2Q81HCD
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50256260 (CHEMBL4094403) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC[C@H](C)NC(=O)[C@H]2CSCc3cc(CSC[C@H](NC1=O)C(O)=O)cc(CSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(N)=N)C(=O)N2)c3 |r| Show InChI InChI=1S/C76H105N19O19S3/c1-40(2)22-53-67(105)94-60(75(113)114)38-117-35-47-24-45-23-46(25-47)34-116-37-59(71(109)84-41(3)30-82-52(28-48-31-80-39-83-48)66(104)87-51(17-18-62(77)99)65(103)89-55(29-63(100)101)69(107)88-53)93-64(102)50(12-8-9-20-81-76(78)79)86-68(106)54(26-44-13-15-49(98)16-14-44)90-73(111)61-19-21-95(61)74(112)56(27-43-10-6-5-7-11-43)91-70(108)57(32-96)92-72(110)58(36-115-33-45)85-42(4)97/h5-7,10-11,13-16,23-25,31,39-41,50-61,82,96,98H,8-9,12,17-22,26-30,32-38H2,1-4H3,(H2,77,99)(H,80,83)(H,84,109)(H,85,97)(H,86,106)(H,87,104)(H,88,107)(H,89,103)(H,90,111)(H,91,108)(H,92,110)(H,93,102)(H,94,105)(H,100,101)(H,113,114)(H4,78,79,81)/t41-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59+,60-,61?/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50256261 (CHEMBL4059991) Show SMILES CC(C)C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CSCc3cc(CSC[C@@H](NC1=O)C(=O)N[C@@H](C)C(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(O)=O)cc(CSC[C@H](NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)N2)c3 |r| Show InChI InChI=1S/C117H160N32O28S3/c1-59(2)37-78-100(161)141-86(105(166)129-60(3)111(172)146(9)52-95(156)145(8)51-94(155)144(7)50-93(154)132-76(27-16-32-124-116(120)121)98(159)133-77(115(176)177)28-17-33-125-117(122)123)57-179-54-65-38-64-39-66(40-65)55-180-58-87(114(175)149-36-20-31-90(149)109(170)137-79(41-67-47-126-73-24-13-10-21-70(67)73)101(162)135-83(46-96(157)158)99(160)130-61(4)112(173)147-34-18-29-88(147)107(168)136-78)142-103(164)80(42-68-48-127-74-25-14-11-22-71(68)74)138-108(169)89-30-19-35-148(89)113(174)84(45-92(119)153)140-102(163)81(43-69-49-128-75-26-15-12-23-72(69)75)139-110(171)97(62(5)150)143-104(165)82(44-91(118)152)134-106(167)85(56-178-53-64)131-63(6)151/h10-15,21-26,38-40,47-49,59-62,76-90,97,126-128,150H,16-20,27-37,41-46,50-58H2,1-9H3,(H2,118,152)(H2,119,153)(H,129,166)(H,130,160)(H,131,151)(H,132,154)(H,133,159)(H,134,167)(H,135,162)(H,136,168)(H,137,170)(H,138,169)(H,139,171)(H,140,163)(H,141,161)(H,142,164)(H,143,165)(H,157,158)(H,176,177)(H4,120,121,124)(H4,122,123,125)/t60-,61-,62+,76+,77+,78-,79-,80-,81-,82-,83-,84-,85-,86+,87-,88-,89-,90-,97-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50459539 (CHEMBL4206734) Show SMILES Cc1nn(c(C)c1NC(=O)COC(=O)Cc1c(C)[nH]c2cc(ccc12)C(N)=N)-c1ccccc1 Show InChI InChI=1S/C25H26N6O3/c1-14-20(19-10-9-17(25(26)27)11-21(19)28-14)12-23(33)34-13-22(32)29-24-15(2)30-31(16(24)3)18-7-5-4-6-8-18/h4-11,28H,12-13H2,1-3H3,(H3,26,27)(H,29,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
German Cancer Research Center (DKFZ) Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured ...				J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525914 (CHEMBL4558285) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccnc1)[C@H]1Cc2ccc(cc2B(O)O1)C(F)(F)F |r| Show InChI InChI=1S/C22H19BF3N3O3.ClH/c24-22(25,26)16-5-3-14-8-19(32-23(30)18(14)10-16)15-4-6-17(21(27)28)20(9-15)31-12-13-2-1-7-29-11-13;/h1-7,9-11,19,30H,8,12H2,(H3,27,28);1H/t19-;/m1./s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM113069 (US9695194, 5) Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1OC Show InChI InChI=1S/C18H17NO5/c1-4-23-16-9-12-13(10-15(16)22-3)19-17(24-18(12)20)11-7-5-6-8-14(11)21-2/h5-10H,4H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of recombinant human KLK14 using S-2302 substrate				Bioorg Med Chem Lett 29: 821-825 (2019) Article DOI: 10.1016/j.bmcl.2019.01.020 BindingDB Entry DOI: 10.7270/Q2S46WGF
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525895 (CHEMBL4447752) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccnc1)C1Cc2ccc(cc2B(O)O1)C(F)(F)F Show InChI InChI=1S/C22H19BF3N3O3.ClH/c24-22(25,26)16-5-3-14-8-19(32-23(30)18(14)10-16)15-4-6-17(21(27)28)20(9-15)31-12-13-2-1-7-29-11-13;/h1-7,9-11,19,30H,8,12H2,(H3,27,28);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525904 (CHEMBL4461533) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccnc1)C1Cc2cc(Cl)c(F)cc2B(O)O1 Show InChI InChI=1S/C21H18BClFN3O3.ClH/c23-17-6-14-8-19(30-22(28)16(14)9-18(17)24)13-3-4-15(21(25)26)20(7-13)29-11-12-2-1-5-27-10-12;/h1-7,9-10,19,28H,8,11H2,(H3,25,26);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525905 (CHEMBL4517343) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccc(Cl)c1)C1Cc2ccccc2B(O)O1 Show InChI InChI=1S/C22H20BClN2O3.ClH/c24-17-6-3-4-14(10-17)13-28-21-12-16(8-9-18(21)22(25)26)20-11-15-5-1-2-7-19(15)23(27)29-20;/h1-10,12,20,27H,11,13H2,(H3,25,26);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525912 (CHEMBL4543039) Show SMILES Cl.NC(=N)c1ccc(CC2OB(O)c3cc(F)ccc23)cc1OCc1cccnc1 Show InChI InChI=1S/C21H19BFN3O3.ClH/c23-15-4-6-16-18(10-15)22(27)29-20(16)9-13-3-5-17(21(24)25)19(8-13)28-12-14-2-1-7-26-11-14;/h1-8,10-11,20,27H,9,12H2,(H3,24,25);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525900 (CHEMBL4460168) Show SMILES Cl.Cc1cccc2CC(OB(O)c12)c1ccc(C(N)=N)c(OCc2cccnc2)c1 Show InChI InChI=1S/C22H22BN3O3.ClH/c1-14-4-2-6-17-11-19(29-23(27)21(14)17)16-7-8-18(22(24)25)20(10-16)28-13-15-5-3-9-26-12-15;/h2-10,12,19,27H,11,13H2,1H3,(H3,24,25);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525899 (CHEMBL4465265) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccnc1)[C@@H]1Cc2ccc(cc2B(O)O1)C(F)(F)F |r| Show InChI InChI=1S/C22H19BF3N3O3.ClH/c24-22(25,26)16-5-3-14-8-19(32-23(30)18(14)10-16)15-4-6-17(21(27)28)20(9-15)31-12-13-2-1-7-29-11-13;/h1-7,9-11,19,30H,8,12H2,(H3,27,28);1H/t19-;/m0./s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525917 (CHEMBL4579813) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1cccnc1)C1Cc2ccccc2B(O)O1 Show InChI InChI=1S/C21H20BN3O3.ClH/c23-21(24)17-8-7-16(11-20(17)27-13-14-4-3-9-25-12-14)19-10-15-5-1-2-6-18(15)22(26)28-19;/h1-9,11-12,19,26H,10,13H2,(H3,23,24);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM51911 ((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...) Show SMILES COc1ccc(cc1)C(CCNCc1ccc(OC(C)C)cc1)c1ccccc1OC Show InChI InChI=1S/C27H33NO3/c1-20(2)31-24-13-9-21(10-14-24)19-28-18-17-25(22-11-15-23(29-3)16-12-22)26-7-5-6-8-27(26)30-4/h5-16,20,25,28H,17-19H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL					Assay Description Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assay				Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM32709 ((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...) Show SMILES Cc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1 Show InChI InChI=1S/C15H13N5O/c1-10-4-6-11(7-5-10)14(21)20-15(16)18-13(19-20)12-3-2-8-17-9-12/h2-9H,1H3,(H2,16,18,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL					Assay Description Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assay				Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525911 (CHEMBL4535907) Show SMILES Cl.NC(=N)c1ccc(cc1OCc1ccccc1Cl)C1Cc2ccccc2B(O)O1 Show InChI InChI=1S/C22H20BClN2O3.ClH/c24-19-8-4-2-6-16(19)13-28-21-12-15(9-10-17(21)22(25)26)20-11-14-5-1-3-7-18(14)23(27)29-20;/h1-10,12,20,27H,11,13H2,(H3,25,26);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525903 (CHEMBL4436048) Show SMILES Cl.NC(=N)c1ccc(CC2OB(O)c3ccccc23)cc1OCc1cccnc1 Show InChI InChI=1S/C21H20BN3O3.ClH/c23-21(24)17-8-7-14(10-19(17)27-13-15-4-3-9-25-12-15)11-20-16-5-1-2-6-18(16)22(26)28-20;/h1-10,12,20,26H,11,13H2,(H3,23,24);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM33453 ((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...) Show SMILES COc1ccc(cc1)C(=O)n1cnnc1N Show InChI InChI=1S/C10H10N4O2/c1-16-8-4-2-7(3-5-8)9(15)14-6-12-13-10(14)11/h2-6H,1H3,(H2,11,13)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL					Assay Description Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assay				Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50522493 (CHEMBL4530083) Show SMILES NC(=N)c1ccc(NCc2nc(c[nH]2)-c2ccccc2)cc1OCc1cccnc1 Show InChI InChI=1S/C23H22N6O/c24-23(25)19-9-8-18(11-21(19)30-15-16-5-4-10-26-12-16)27-14-22-28-13-20(29-22)17-6-2-1-3-7-17/h1-13,27H,14-15H2,(H3,24,25)(H,28,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal 10His-tagged human KLK14 (Gln19 to Met248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate ...				Bioorg Med Chem Lett 29: 1454-1458 (2019) Article DOI: 10.1016/j.bmcl.2019.04.022 BindingDB Entry DOI: 10.7270/Q24F1V4V
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50459538 (CHEMBL4218203) Show SMILES Cc1nn(c(C)c1NC(=O)COC(=O)Cc1c(C)[nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H24N4O3/c1-15-20(19-11-7-8-12-21(19)25-15)13-23(30)31-14-22(29)26-24-16(2)27-28(17(24)3)18-9-5-4-6-10-18/h4-12,25H,13-14H2,1-3H3,(H,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
German Cancer Research Center (DKFZ) Curated by ChEMBL					Assay Description Inhibition of KLK14 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured ...				J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B
					More data for this Ligand-Target Pair
Kallikrein-14 (Homo sapiens (Human))	BDBM50525918 (CHEMBL4473069) Show SMILES Cl.NC(=N)c1ccc(CC2OB(O)c3cc(ccc23)C(F)(F)F)cc1OCc1cccnc1 Show InChI InChI=1S/C22H19BF3N3O3.ClH/c24-22(25,26)15-4-6-16-18(10-15)23(30)32-20(16)9-13-3-5-17(21(27)28)19(8-13)31-12-14-2-1-7-29-11-14;/h1-8,10-11,20,30H,9,12H2,(H3,27,28);1H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal 10-His-tagged KLK14 (Q19 to M248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate inc...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 BindingDB Entry DOI: 10.7270/Q2571GG1
					More data for this Ligand-Target Pair

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