Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl endopeptidase (Mus musculus) | BDBM50038879 ((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Inhibition of mouse brain POP | J Med Chem 53: 3423-38 (2010) Article DOI: 10.1021/jm901104g BindingDB Entry DOI: 10.7270/Q261119N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279827 (2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-2,3-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.40 | n/a | n/a | n/a | n/a | 0.000300 | 1.40E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50316840 ((R)-benzyl 2-((S)-2-formylpyrrolidine-1-carbonyl)i...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Inhibition of mouse brain POP | J Med Chem 53: 3423-38 (2010) Article DOI: 10.1021/jm901104g BindingDB Entry DOI: 10.7270/Q261119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279825 ((1R,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 3 | n/a | n/a | n/a | n/a | 0.00200 | 7.00E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279826 ((1S,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 3 | n/a | n/a | n/a | n/a | 0.000700 | 2.30E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279825 ((1R,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for binding inhibition against Prolyl Endopeptidase (PEP). | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279826 ((1S,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Inhibition of mouse brain POP | J Med Chem 53: 3423-38 (2010) Article DOI: 10.1021/jm901104g BindingDB Entry DOI: 10.7270/Q261119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50316836 ((9H-fluoren-9-yl)methyl(S)-1-((S)-2-cyanopyrrolidi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Inhibition of mouse brain POP | J Med Chem 53: 3423-38 (2010) Article DOI: 10.1021/jm901104g BindingDB Entry DOI: 10.7270/Q261119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50155838 ((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50005870 (CHEMBL3236271) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Competitive inhibition of mouse brain prolyl oligopeptidase | Eur J Med Chem 79: 436-45 (2014) Article DOI: 10.1016/j.ejmech.2014.04.014 BindingDB Entry DOI: 10.7270/Q2G162BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529486 (CHEMBL4549821) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50051539 ((S)-4-phenyl-1-(2-(pyrrolidine-1-carbonyl)pyrrolid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Inhibition of mouse brain POP | J Med Chem 53: 3423-38 (2010) Article DOI: 10.1021/jm901104g BindingDB Entry DOI: 10.7270/Q261119N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529474 (CHEMBL4528594) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529487 (CHEMBL4465322) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529483 (CHEMBL4556841) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 298 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529494 (CHEMBL4540171) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529475 (CHEMBL4588059) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529484 (CHEMBL4586782) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529491 (CHEMBL4520738) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529485 (CHEMBL4475037) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529489 (CHEMBL4551013) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529495 (CHEMBL4441906) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50529490 (CHEMBL4436952) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s... | ACS Med Chem Lett 10: 1635-1640 (2019) Article DOI: 10.1021/acsmedchemlett.9b00394 BindingDB Entry DOI: 10.7270/Q2542S18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279826 ((1S,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000700 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (koff) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279825 ((1R,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.00200 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (koff) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279827 (2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-2,3-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000300 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (koff) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279826 ((1S,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 2.30E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase (Mus musculus) | BDBM50279827 (2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-2,3-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 1.40E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | Bioorg Med Chem Lett 1: 585-590 (1991) Article DOI: 10.1016/S0960-894X(01)81156-2 BindingDB Entry DOI: 10.7270/Q2SQ909F | |||||||||||
More data for this Ligand-Target Pair |