BindingDB PrimarySearch

Found 4 hits for UniProtKB: Q00651
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-4/beta-7 (Mus musculus)	BDBM50390576 (CHEMBL2069363) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of alpha4beta7 assessed as inhibition of Mn(2+)-activated adhesion of mouse TK-1 T cells to mouse MAdCAM-1 incubated for 1 hr by cell adhe...				Bioorg Med Chem 20: 5139-49 (2012) Article DOI: 10.1016/j.bmc.2012.07.010 BindingDB Entry DOI: 10.7270/Q20866DH
University of Auckland Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-4/beta-7 (Mus musculus)	BDBM50390574 (CHEMBL2069362) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of alpha4beta7 assessed as inhibition of Mn(2+)-activated adhesion of mouse TK-1 T cells to mouse MAdCAM-1 incubated for 1 hr by cell adhe...				Bioorg Med Chem 20: 5139-49 (2012) Article DOI: 10.1016/j.bmc.2012.07.010 BindingDB Entry DOI: 10.7270/Q20866DH
University of Auckland Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-4/beta-7 (Mus musculus)	BDBM50390575 (CHEMBL2069369) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of alpha4beta7 assessed as inhibition of Mn(2+)-activated adhesion of mouse TK-1 T cells to mouse MAdCAM-1 incubated for 1 hr by cell adhe...				Bioorg Med Chem 20: 5139-49 (2012) Article DOI: 10.1016/j.bmc.2012.07.010 BindingDB Entry DOI: 10.7270/Q20866DH
University of Auckland Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-4/beta-7 (Mus musculus)	BDBM50380113 (CHEMBL2013109) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of integrin alpha4 beta7 receptor in mouse TK1 cells assessed as inhibition of Mn2+-activated cell adhesion to mouse MAdCAM-1-Fc after 1 h...				Bioorg Med Chem 20: 2638-44 (2012) Article DOI: 10.1016/j.bmc.2012.02.035 BindingDB Entry DOI: 10.7270/Q2TQ62H4
University of Auckland Curated by ChEMBL					More data for this Ligand-Target Pair