Search by Patent Identification

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Patent: (prefix with "US" like US6078908)

Patent	Data	Compounds	HGNC (for human-derived proteins)	Patent Title	Organization	Deposition	Downloads
US11028054	35	35	HGNC:2867	1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors	Merck Patent GmbH	11/29/21	2D 3D TSV
US11021493	720	180	HGNC:934 HGNC:2529 HGNC:933	1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use	Amgen Inc.	11/29/21	2D 3D TSV
US11026923	606	195	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	11/29/21	2D 3D TSV
US11028101	3	3	HGNC:10894	3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	11/29/21	2D 3D TSV
US11028093	867	209	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors	ARRAY BIOPHARMA INC.; CELGENE CORPORATION	11/29/21	2D 3D TSV
US11021475	37	37		Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses	Bristol-Myers Squibb Company	11/29/21	2D 3D TSV
US11021511	20	6		Cyclic dinucleotides as sting agonists	Janssen Biotech, Inc.	11/29/21	2D 3D TSV
US11028083	163	148	HGNC:23393 HGNC:18241	Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases	Board of Regents, The University of Texas System	11/29/21	2D 3D TSV
US11026937	134	134	HGNC:18368	Heteroaryl inhibitors of PAD4	Padlock Therapeutics, Inc.	11/29/21	2D 3D TSV
US11028067	15	8	HGNC:12437 HGNC:4623	Heteroarylsulfonyl-substituted pyridines and their use in the treatment of cancer	Oblique Therapeutics AB	11/29/21	2D 3D TSV
US11028058	12	12	HGNC:263	Heterocyclic compounds as adenosine antagonists	NUVATION BIO INC.	11/29/21	2D 3D TSV
US11021478	24	24	HGNC:1232	Indolizine derivatives and their application in medicine	KIND PHARMACEUTICAL	11/29/21	2D 3D TSV
US11028066	97	97	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	11/29/21	2D 3D TSV
US11021467	405	135	HGNC:8978 HGNC:8980 HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences, Inc.	11/29/21	2D 3D TSV
US11026936	57	34	HGNC:8810	Piperidinyl-propanone derivatives	Merck Patent GmbH	11/29/21	2D 3D TSV
US11028041	36	18	HGNC:5253	Second generation GRP94-selective inhibitors	University of Kansas	11/29/21	2D 3D TSV
US11026958	41	41	HGNC:1960	Substituted 6-membered aryl or heteroaryl allosteric modulators of nicotinic acetylcholine receptors	Merck Sharp & Dohme Corp.	11/29/21	2D 3D TSV
US11021481	837	837	HGNC:6863	Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists	Nimbus Saturn, Inc.	11/29/21	2D 3D TSV
US11028085	837	823	HGNC:6863	Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as hpk1 antagonists	Nimbus Saturn, Inc.	11/29/21	2D 3D TSV
US11028092	124	60	HGNC:8795	Substituted pyrazolo[3,4-d]pyrimidines as PDE9 inhibitors	Merck Sharp & Dohme Corp.	11/29/21	2D 3D TSV
US11028080	44	44		Substituted pyrimidines as LRKK2 inhibitors	DENALI THERAPEUTICS INC.	11/29/21	2D 3D TSV
US11028051	14	7		Tetrahydroquinoline-based bromodomain inhibitors	St. Jude Children''s Research Hospital	11/29/21	2D 3D TSV
US11028075	182	92	HGNC:10597	Therapeutic compounds and methods of use thereof	Genentech, Inc.	11/29/21	2D 3D TSV
US11021463	202	145	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	11/29/21	2D 3D TSV
US11021515	404	207		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	11/29/21	2D 3D TSV
US11028064	146	76	HGNC:6307	Tricyclic heterocyclic derivatives and uses thereof	AUCKLAND UNISERVICES LIMITED	11/29/21	2D 3D TSV
US11028104	83	42	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V.	11/29/21	2D 3D TSV
US11028090	505	504	HGNC:13575	[1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient	Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology	11/29/21	2D 3D TSV
US11020398	376	303	HGNC:1133	Amino-pyrrolopyrimidinone compounds and methods of use thereof	ArQule, Inc.	11/28/21	2D 3D TSV
US11020381	174	169	HGNC:10597	Biaryloxy derivatives as TTX-S blockers	RaQualia Pharma Inc.; XuanZhu Pharma Co., Ltd.	11/28/21	2D 3D TSV
US11021457	150	150		Class of isoindolone-imide ring-1,3-dione-2-ene compounds, composition and use thereof	WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD.	11/28/21	2D 3D TSV
US11020397	70	44	HGNC:12805 HGNC:17989	Compounds and their use for reducing uric acid levels	Acquist LLC	11/28/21	2D 3D TSV
US11020395	154	154	HGNC:339	Cycloalkyl substituted triazole compounds as agonists of the APJ receptor	AMGEN INC.	11/28/21	2D 3D TSV
US11020380	410	396	HGNC:2348	Therapeutic compounds	CELGENE QUANTICEL RESEARCH, INC.	11/28/21	2D 3D TSV
US11021454	44	27	HGNC:12805	Type of aryl benzofuran amidated derivative and medical use thereof	CHINA PHARMACEUTICAL UNIVERSITY	11/28/21	2D 3D TSV
US11014905	114	36	HGNC:3023 HGNC:5286	2,6-disubstituted pyridine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	11/22/21	2D 3D TSV
US11014923	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	11/22/21	2D 3D TSV
US11014911	1035	649	HGNC:1780 HGNC:1771 HGNC:4617 HGNC:1777 HGNC:1722 HGNC:1773	CDK2 inhibitors	Pfizer Inc.	11/22/21	2D 3D TSV
US11014912	68	68		Cyanopyrrolidine derivatives with activity as inhibitors of USP30	MISSION THERAPEUTICS LIMITED	11/22/21	2D 3D TSV
US11014920	36	36	HGNC:3530	Factor XIIa inhibitors	Merck Sharp & Dohme Corp.	11/22/21	2D 3D TSV
US11014930	78	78	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	11/22/21	2D 3D TSV
US11014909	81	72	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc.	11/22/21	2D 3D TSV
US11013718	9	9	HGNC:29079	LSD1 inhibitors and medical uses thereof	Constellation Pharmaceuticals, Inc.	11/22/21	2D 3D TSV
US11014929	126	126	HGNC:6863	Pyrazolopyrimidine compounds and uses thereof	Incyte Corporation	11/22/21	2D 3D TSV
US11014913	855	800		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics, Inc.	11/22/21	2D 3D TSV
US11014926	35	30	HGNC:7110 HGNC:7111	Pyrrolo-, pyrazolo-, imidazo-pyrimidine and pyridine compounds that inhibit MNK1 and MNK2	eFFECTOR Therapeutics, Inc.	11/22/21	2D 3D TSV
US11013745	80	80		Triazolopyrimidine, triazolopyridine compounds, and the composition thereof for treating PRC2-mediated diseases	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.	11/22/21	2D 3D TSV
US11014963	205	205		Trifluoromethylpropanamide derivatives as HTRA1 inhibitors	Hoffmann-La Roche Inc.	11/22/21	2D 3D TSV
US11008338	48	25	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	11/15/21	2D 3D TSV
US11008314	623	156	HGNC:1133 HGNC:6193 HGNC:6171 HGNC:12434	Compounds and methods for modulating interleukin-2-inducible t-cell kinase	Corvus Pharmaceuticals, Inc.	11/15/21	2D 3D TSV
US11008336	22	8	HGNC:10259 HGNC:10258	Compounds useful for inhibiting RORγt	Eli Lilly and Company	11/15/21	2D 3D TSV
US11007200	16	8	HGNC:8157	Cycloalkyl-diamines for the treatment of pain	MediSynergics, LLC	11/14/21	2D 3D TSV
US11008301	42	21	HGNC:3827 HGNC:3826	Piperidinone formyl peptide 2 receptor agonists	Bristol-Myers Squibb Company	11/14/21	2D 3D TSV
US11008312	373	372		Pyridazine derivatives as RORc modulators	Genentech, Inc.	11/14/21	2D 3D TSV
US11008308	435	425	HGNC:29232	Quinazolinones as PARP14 inhibitors	Ribon Therapeutics Inc.	11/14/21	2D 3D TSV
US11008304	85	85	HGNC:6857	Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	11/14/21	2D 3D TSV
US11000525	30	15	HGNC:7218 HGNC:12015	1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase	ASTRAZENECA AB	11/08/21	2D 3D TSV
US11001596	70	14	HGNC:5383 HGNC:5382	7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitors	Eli Lilly and Company	11/08/21	2D 3D TSV
US11001586	178	89	HGNC:7027 HGNC:12446	Alkyl pyrrolopyrimidine analogs and methods of making and using same	The University of North Carolina at Chapel Hill	11/08/21	2D 3D TSV
USRE48547	6	6	HGNC:6027	Aminopyrimidinecarboxamides as CXCR2 modulators	Syntrix Biosystems Inc.	11/08/21	2D 3D TSV
US11001575	923	900	HGNC:6871	Benzolactam compounds as protein kinase inhibitors	OTSUKA PHARMACEUTICAL CO., LTD.	11/08/21	2D 3D TSV
US11000528	26	11		Compound useful for the treatment of degenerative and inflammatory diseases	GALAPAGOS NV	11/08/21	2D 3D TSV
US10995099	93	65	HGNC:85 HGNC:84	Compounds and their uses as ACC inhibitors	Nanjing Ruijie Pharmatech Co., Ltd.	11/08/21	2D 3D TSV
US11000515	25	25		Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease	Shy Therapeutics LLC	11/08/21	2D 3D TSV
US11001555	22	22		Difluoroketamide derivatives as HTRA1 inhibitors	Hoffman-La Roche Inc.	11/08/21	2D 3D TSV
US11001583	16	16		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	11/08/21	2D 3D TSV
US11001600	13	13	HGNC:2771	Disubstituted compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	11/08/21	2D 3D TSV
US11001568	170	44	HGNC:29012 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	11/08/21	2D 3D TSV
US11001578	188	92	HGNC:6371 HGNC:6357	N-((HET)arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	KALVISTA PHARMACEUTICALS LIMITED	11/08/21	2D 3D TSV
US11001589	51	51	HGNC:3650	Pyrazole derivatives useful as 5-lipoxygenase activating protein (FLAP) inhibitors	ASTRAZENECA AB	11/08/21	2D 3D TSV
US11001595	32	14	HGNC:3763 HGNC:2861 HGNC:6307 HGNC:8804 HGNC:3236	Pyrimidine compounds and pyrimido indole compounds and methods of use	Duquesne University of The Holy Spirit	11/08/21	2D 3D TSV
US11001572	40	10	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine derivative, method for preparing same and use thereof in medicine	TBA	11/08/21	2D 3D TSV
US11001561	146	146	HGNC:9644	Pyrimidinone derivatives as SHP2 antagonists	Merck Patent GmbH	11/08/21	2D 3D TSV
US11001563	81	81	HGNC:550	SSAO inhibitor	TBA	11/08/21	2D 3D TSV
US10995070	15	15	HGNC:84	Acetyl-CoA carboxylase modulators	Monsanto Technology LLC	11/04/21	2D 3D TSV
US10994015	521	108	HGNC:3430 HGNC:3431 HGNC:3236	EGFR proteolysis targeting chimeric molecules and associated methods of use	ARVINAS OPERATIONS, INC.; YALE UNIVERSITY	11/04/21	2D 3D TSV
US10995072	124	57	HGNC:3538	Inhibitors of protease-activated receptor-2	Heptares Therapeutics Limited	11/04/21	2D 3D TSV
US10995088	309	162	HGNC:6833 HGNC:6834 HGNC:2671 HGNC:6664 HGNC:6666	Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer	THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL	11/04/21	2D 3D TSV
US10995073	253	218	HGNC:8605 HGNC:270	PARG inhibitory compounds	Cancer Research Technology Limited	11/04/21	2D 3D TSV
US10995084	192	116	HGNC:16709	Pyrrolidine derivative	KISSEI PHARMACEUTICAL CO., LTD.	11/04/21	2D 3D TSV
US10995090	21	19	HGNC:7056	Substituted dihydrobenzofuran glycosidase inhibitors	Asceneuron SA	11/04/21	2D 3D TSV
US10995089	92	92	HGNC:6871	Zaindole derivatives and their use as ERK kinase inhibitors	AGV DISCOVERY; INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE MONTPELLIER	11/04/21	2D 3D TSV
US10988455	108	53	HGNC:262 HGNC:263	1,2,4-triazine-4-amine derivatives	Heptares Therapeutics Limited	11/01/21	2D 3D TSV
US10988502	64	32	HGNC:6561 HGNC:6563	Alpha-D-galactoside inhibitors of galectins	GALECTO BIOTECH AB	11/01/21	2D 3D TSV
US10988458	71	70	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	11/01/21	2D 3D TSV
US10988459	91	77		Bicyclic lactams and methods of use thereof	Genentech, Inc.	11/01/21	2D 3D TSV
US10988445	310	136		Compounds	AstraZeneca AB	11/01/21	2D 3D TSV
US10988482	108	99	HGNC:17967	IRAK4 inhibitor and use thereof	BEIJING HANMI PHARMACEUTICAL CO., LTD.	11/01/21	2D 3D TSV
US10988507	2	2		Immunomodulators	bristol-myers squibb company	11/01/21	2D 3D TSV
US10987354	24	23		Inhibitors of influenza virus replication and uses thereof	SUNSHINE LAKE PHARMA CO., LTD.	11/01/21	2D 3D TSV
US10988451	457	440		MCL-1 inhibitors	Gilead Sciences, Inc.	11/01/21	2D 3D TSV
US10988481	66	20	HGNC:8153 HGNC:8154 HGNC:8156	Potent and selective mu opioid receptor modulators	Virginia Commonwealth University	11/01/21	2D 3D TSV
US10988462	37	37	HGNC:11036	Pyrazole compounds substituted with heteroaryl and pharmaceutical use thereof	Japan Tobacco Inc.	11/01/21	2D 3D TSV
US10988478	551	532	HGNC:17967	Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators	Genentech, Inc.	11/01/21	2D 3D TSV
US10988463	79	55		Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors	Pfizer Inc.	11/01/21	2D 3D TSV
US10988487	242	204	HGNC:6059	Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors	Merck Sharp & Dohme Corp.	11/01/21	2D 3D TSV
US10988476	635	140	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:1774 HGNC:1773	Substituted pyrimidines as cyclin-dependent kinase inhibitors	SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.	11/01/21	2D 3D TSV
US10981917	230	229	HGNC:9462	Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same	Daewoong Pharmaceutical Co., Ltd.	10/27/21	2D 3D TSV
US10981916	25	25		Substituted pyrazolopyrimidinone compounds as PDE2 inhibitors	DART NEUROSCIENCE, LLC	10/27/21	2D 3D TSV
US10981926	3	1	HGNC:7978 HGNC:644	Substituted thiohydantoin derivatives as androgen receptor antagonists	Janssen Pharmaceutica NV	10/27/21	2D 3D TSV
US10981914	16	11	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Companay	10/27/21	2D 3D TSV
US10981904	67	61		1,3,4-thiadiazole compounds and their use in treating cancer	Cancer Research Technology Limited	10/26/21	2D 3D TSV
US10980781	21	18	HGNC:12630	6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use	Purdue Research Foundation	10/26/21	2D 3D TSV
US10980815	468	113	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aminopyrimidinyl compounds	Pfizer Inc.	10/26/21	2D 3D TSV
US10981887	50	25	HGNC:3467	Benzothiophene estrogen receptor modulators	G1 Therapeutics, Inc.	10/26/21	2D 3D TSV
US10981910	237	236	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	10/26/21	2D 3D TSV
US10981882	19	19	HGNC:6059	Compound for inhibiting IDO, a manufacturing method and a use thereof	Shanghai JOYU Pharmatech Ltd.	10/26/21	2D 3D TSV
US10981881	16	8	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences, Inc.	10/26/21	2D 3D TSV
US10981905	154	49	HGNC:10593 HGNC:10585 HGNC:10596	Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	10/26/21	2D 3D TSV
US10981911	840	210		Imidazopyrrolopyridine as inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	10/26/21	2D 3D TSV
US10981896	43	22	HGNC:16870 HGNC:1925 HGNC:1470 HGNC:9377 HGNC:14311 HGNC:6871	Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	10/26/21	2D 3D TSV
US10981899	9	5	HGNC:21285	Inhibitors of soluble adenylyl cyclase	Cornell University; Tri-Institutional Therapeutics Discovery Institute	10/26/21	2D 3D TSV
US10981898	89	85		Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity	ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED	10/26/21	2D 3D TSV
US10980794	334	329		PRMT5 inhibitors and uses thereof	Epizyme, Inc.	10/26/21	2D 3D TSV
US10981906	110	51	HGNC:6190	Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same	ACLARIS THERAPEUTICS, INC.	10/26/21	2D 3D TSV
US10981893	35	30	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	10/26/21	2D 3D TSV
US10981879	189	164	HGNC:7218	Thioether triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	10/26/21	2D 3D TSV
US10980809	132	95	HGNC:6307 HGNC:9829 HGNC:1097	Urea-substituted aromatic ring-linked dioxane-quinazoline and -linked dioxane-quinoline compounds, preparation method therefor and use thereof	BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED	10/26/21	2D 3D TSV
US10975062	135	135		4-aminoquinazolinyl compounds as prolyl hydroxylase inhibitors	TBA	10/20/21	2D 3D TSV
US10975057	94	92		6-aminopyridin-3-yl pyrazoles as modulators of RORgT	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975068	453	441		6-aminopyridin-3-yl thiazoles as modulators of RORγT	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975066	25	25	HGNC:11138	Bis-heteroaryl derivatives as modulators of protein aggregation	UCB Biopharma SRL	10/20/21	2D 3D TSV
US10975080	72	71	HGNC:9644	Compounds and compositions for inhibiting the activity of SHP2	NOVARTIS AG	10/20/21	2D 3D TSV
US10975030	28	28	HGNC:5253	Grp94 selective inhibitors and uses thereof	University of Kansas; University of South Florida	10/20/21	2D 3D TSV
US10975075	471	134	HGNC:8978 HGNC:795 HGNC:8975 HGNC:3942 HGNC:8977 HGNC:8976	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	10/20/21	2D 3D TSV
US10975058	8	4	HGNC:4840 HGNC:1133	Imidazolyl kinase inhibitors and uses thereof	Dana-Farber Cancer Institute, Inc.	10/20/21	2D 3D TSV
US10975084	185	185	HGNC:18039	KDM5 inhibitors	Merck Sharp & Dohme Corp.	10/20/21	2D 3D TSV
US10975049	22	22		Nicotinyl alcohol ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	10/20/21	2D 3D TSV
US10973817	147	146	HGNC:1925	Pharmaceutical compounds	SENTINEL ONCOLOGY LIMITED	10/20/21	2D 3D TSV
US10975037	228	225		Phenyl substituted pyrazoles as modulators of RORγt	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975091	290	150	HGNC:6656	Pyridine derivative	Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD.	10/20/21	2D 3D TSV
US10975064	27	27		RIP1 inhibitory compounds and methods for making and using the same	Rigel Pharmaceuticals, Inc.	10/20/21	2D 3D TSV
US10975081	18	16	HGNC:18618	Substituted fused pyrazole compounds and their use as LRRK2 inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED	10/20/21	2D 3D TSV
US10975056	659	645	HGNC:2976	Substituted pyridines as inhibitors of DNMT1	GlaxoSmithKline Intellectual Property Development Limited; Cancer Research Technology Ltd.	10/20/21	2D 3D TSV
US10968216	332	297	HGNC:2867	4,5-annulated 1,2,4-triazolones	BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION	10/09/21	2D 3D TSV
US10968163	97	34	HGNC:3560 HGNC:3557	Alpha-truxillic acid derivatives and pharmaceutical compositions thereof	The Research Foundation for the State University of New York	10/09/21	2D 3D TSV
US10968188	153	114	HGNC:8803 HGNC:76 HGNC:6342	Benzothiazol compounds and methods using the same for treating neurodegenerative disorders	1st Biotherapeutics, Inc.	10/09/21	2D 3D TSV
US10968198	35	35	HGNC:7097	Biaryltriazole inhibitors of macrophage migration inhibitory factor	Yale University	10/09/21	2D 3D TSV
US10968199	30	29	HGNC:6857	Cycloalkyl-containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	10/09/21	2D 3D TSV
US10968242	106	35		Cyclopentane-based modulators of STING (stimulator of interferon genes)	Pfizer Inc.	10/09/21	2D 3D TSV
US10968213	375	107	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Company Limited	10/09/21	2D 3D TSV
US10968223	155	155	HGNC:550	Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors	Proximagen, LLC	10/09/21	2D 3D TSV
US10968227	45	45	HGNC:4596	Isoquinoline ether compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/09/21	2D 3D TSV
US10966985	52	13	HGNC:10261	Macrocyclic compounds as ROS1 kinase inhibitors	Array BioPharma Inc.	10/09/21	2D 3D TSV
US10968215	227	189	HGNC:3527	Pyrido five-element aromatic ring compound, preparation method therefor and use thereof	SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	10/09/21	2D 3D TSV
US10966980	1100	273	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrrolo[2,3-d]pyrimidine derivatives	Pfizer Inc.	10/09/21	2D 3D TSV
US10968221	13	13	HGNC:29079	Substituted [1,2,4]triazolo[1,5-a]pyrazines as LSD1 inhibitors	Incyte Corporation	10/09/21	2D 3D TSV
US10967060	22	22	HGNC:6059	Synergistic combination of immunologic inhibitors for the treatment of cancer	The University of Chicago	10/09/21	2D 3D TSV
US10968236	184	91	HGNC:6192 HGNC:12440	TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	10/09/21	2D 3D TSV
US10966987	23	23	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	10/09/21	2D 3D TSV
US10968172	90	90		USP30 inhibitors	Mitobridge, Inc.	10/09/21	2D 3D TSV
US10961236	249	63	HGNC:8975 HGNC:8977 HGNC:8976	(S)-2-(1-cyclopropylethyl)-5-(4-methyl-2-((6-(2-oxopyrrolidin-1-yl)pyridin-2-yl)amino) thiazol-5-yl)-7-(methylsulfonyl)isoindolin-1-one as a phosphatidylinositol 3-kinase inhibitor	AstraZeneca AB	10/04/21	2D 3D TSV
US10961241	73	66		Chemical compounds	AstraZeneca AB	10/04/21	2D 3D TSV
US10961242	81	80	HGNC:3357	Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same	LegoChem Biosciences, Inc.	10/04/21	2D 3D TSV
US10961198	66	66	HGNC:7967	Farnesoid X receptor agonists and uses thereof	METACRINE, INC.	10/04/21	2D 3D TSV
US10961237	146	145	HGNC:1133	Inhibiting agents for Bruton's tyrosine kinase	BIOGEN MA INC.	10/04/21	2D 3D TSV
US10961228	198	66		JAK1 selective inhibitors	ASTRAZENECA AB	10/04/21	2D 3D TSV
US10961249	21	21		Modulators of the sigma-2 receptor and their method of use	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	10/04/21	2D 3D TSV
US10961233	46	45		Oxazole derivatives for use in the treatment of cancer	LIFEARC	10/04/21	2D 3D TSV
US10961256	3	3	HGNC:10894	PRMT5 inhibitors	CTXT PTY LTD	10/04/21	2D 3D TSV
US10961247	365	180	HGNC:1133 HGNC:6193	Pyrazolopyrimidine derivatives as kinase inhibitor	Daewoong Pharmaceutical Co., Ltd.	10/04/21	2D 3D TSV
US10961252	34	34	HGNC:1037	Quinazoline and indole compounds to treat medical disorders	Achillion Pharmaceuticals, Inc.	10/04/21	2D 3D TSV
US10961200	522	512	HGNC:6535	Small molecule inhibitors of lactate dehydrogenase and methods of use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; VANDERBILT UNIVERSITY; THE UAB RESEARCH FOUNDATION; THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	10/04/21	2D 3D TSV
US10961232	603	569	HGNC:882	Substituted pyrazines as ATR kinase inhibitors	VERTEX PHARMACEUTICALS INCORPORATED	10/04/21	2D 3D TSV
US10960005	122	119	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	CELGENE QUANTICEL RESEARCH, INC.	10/04/21	2D 3D TSV
US10954228	149	145	HGNC:6535	1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; THE UAB RESEARCH FOUNDATION; VANDERBILT UNIVERSITY; NATIONAL INSTITUTES OF HEALTH, UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES	09/28/21	2D 3D TSV
US10954253	76	75	HGNC:12761	1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one derivative as Wee1 inhibitor	SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.	09/28/21	2D 3D TSV
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US10954216	119	90	HGNC:171	BMP-signal-inhibiting compound	RIKEN; THE UNIVERSITY OF TOKYO	09/28/21	2D 3D TSV
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US10954241	320	108	HGNC:6307 HGNC:9967	Heterocyclic compounds as ret kinase inhibitors	Cancer Research Technology Limited	09/28/21	2D 3D TSV
US10953012	420	239	HGNC:2459	Heterocyclic compounds for the inhibition of pask	BioEnergenix LLC	09/28/21	2D 3D TSV
US10954237	56	19	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	Theravance Biopharma R&D IP, LLC	09/28/21	2D 3D TSV
US10947254	1048	261	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Methods for treating ulcerative colitis using 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile	Theravance Biopharma R&D IP, LLC	09/28/21	2D 3D TSV
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US10954214	449	444	HGNC:6819	Pyrazole derivatives as MALT1 inhibitors	Janssen Pharmaceutica NV	09/28/21	2D 3D TSV
US10954225	28	15		Selective NR2B antagonists	Bristol-Myers Squibb Company	09/28/21	2D 3D TSV
US10954217	86	43	HGNC:8157	Sigma receptor binders	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	09/28/21	2D 3D TSV
US10954243	22	22		Substituted heterocyclic inhibitors of PTPN11	NAVIRE PHARMA, INC.	09/28/21	2D 3D TSV
US10954193	147	134	HGNC:6943 HGNC:992 HGNC:990	Substituted indole Mcl-1 inhibitors	Vanderbilt University	09/28/21	2D 3D TSV
US10953005	1229	556	HGNC:9967	Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors	Array Biopharma Inc.	09/28/21	2D 3D TSV
US10947203	176	88	HGNC:7968	1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor	ST. JUDE CHILDREN''S RSEARCH HOSPITAL	09/26/21	2D 3D TSV
US10947218	616	87		Aminopyridine derivatives and their use as selective ALK-2 inhibitors	NOVARTIS AG	09/26/21	2D 3D TSV
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US10947230	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Corporation; Incyte Holdings Corporation	09/26/21	2D 3D TSV
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US10947229	48	12	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Dimethyl amino azetidine amides as JAK inhibitors	Theravance Biopharma R&D IP, LLC	09/26/21	2D 3D TSV
US10947243	391	79	HGNC:11390 HGNC:4617 HGNC:3765	Heteroaryl SYK inhibitors	Boehringer Ingelheim International GmbH	09/26/21	2D 3D TSV
US10947215	458	449		Heteroaryl compounds and their use as therapeutic drugs	Dong-A Socio Holdings Co., Ltd.	09/26/21	2D 3D TSV
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US10947210	164	135		Inhibitors of Hepatitis C virus polymerase	COCRYSTAL PHARMA, INC.	09/26/21	2D 3D TSV
US10947252	558	547		Inhibitors of KEAP1-Nrf2 protein-protein interaction	Janssen Pharmaceutica NV	09/26/21	2D 3D TSV
US10946019	33	33	HGNC:10477	Nurr1:RXR activating compounds for simultaneous treatment of symptoms and pathology of Parkinson's disease	TBA	09/26/21	2D 3D TSV
US10947234	36	12	HGNC:10894	PRMT5 inhibitors	Merck Sharp & Dohme Corp.	09/26/21	2D 3D TSV
US10947241	26	26		Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same	Seoul National University Hospital	09/26/21	2D 3D TSV
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US10945978	12	6	HGNC:7966 HGNC:7965	Treatment and diagnosis of melanoma	The Rockefeller University	09/26/21	2D 3D TSV
US10947239	8	1	HGNC:8778	[1,2,4]triazolo[1,5-a]pyrimidin-7-yl compound	Janssen Pharmaceutica NV	09/26/21	2D 3D TSV
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US10940139	25	25		Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease	Shy Therapeutics LLC	09/20/21	2D 3D TSV
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US10941115	196	72	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6524 HGNC:6876	Kinase inhibitors	Oxular Acquisitions Limited	09/20/21	2D 3D TSV
US10941146	31	31		Methods for inhibiting fascin	NOVITA PHARMACEUTICALS, INC.; CORNELL UNIVERSITY	09/20/21	2D 3D TSV
US10941138	193	88	HGNC:1399	Quinoline and isoquinoline derivatives for treating pain and pain related conditions	ESTEVE PHARMACEUTICALS, S.A.	09/20/21	2D 3D TSV
US10934296	665	131	HGNC:6735 HGNC:4037 HGNC:1133 HGNC:11283 HGNC:6524	4-imidazopyridazin-1-yl-benzamides as Btk inhibitors	Merck Sharp & Dohme B.V.	09/12/21	2D 3D TSV
US10934297	286	143	HGNC:4617 HGNC:3091	5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof	Samumed, LLC	09/12/21	2D 3D TSV
US10934303	124	28	HGNC:3474 HGNC:3473 HGNC:3471 HGNC:3467	Aryl ethene derivative and pharmaceutical composition containing same as active ingredient	DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION; KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL; KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION	09/12/21	2D 3D TSV
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US10934285	61	61		Compounds and compositions for inhibiting the activity of SHP2	NOVARTIS AG	09/12/21	2D 3D TSV
US10934310	484	472	HGNC:1133	Inhibitors of Bruton's tyrosine kinase and method of their use	Janssen Pharmaceutica NV	09/12/21	2D 3D TSV
US10934288	241	236	HGNC:6863	Pyrazolopyridine compounds and uses thereof	Incyte Corporation	09/12/21	2D 3D TSV
US10934305	54	32	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	09/12/21	2D 3D TSV
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US10934304	88	87	HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	09/12/21	2D 3D TSV
US10934294	124	60		Substituted pyrazolo[3,4-d]pyrimidines as PDE9 inhibitors	Merck Sharp & Dohme Corp.	09/12/21	2D 3D TSV
US10927106	45	44	HGNC:3091	Benzothiazole derivatives as DYRK1 inhibitors	PHARMASUM THERAPEUTICS AS	09/06/21	2D 3D TSV
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US10927110	31	31		Cyano-subtituted heterocycles with activity as inhibitors of USP30	MISSION THERAPEUTICS LIMITED	09/06/21	2D 3D TSV
US10927076	96	48	HGNC:5258 HGNC:5253	HSP90B N-terminal isoform-selective inhibitors	University of Kansas	09/06/21	2D 3D TSV
US10927111	79	62	HGNC:9829	Inhibitors of RAF kinases	KINNATE BIOPHARMA INC.	09/06/21	2D 3D TSV
US10927079	74	69	HGNC:8031	Intermediate compound of novel tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	09/06/21	2D 3D TSV
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US10927128	113	112	HGNC:575	Oxadiazaspiro compounds for the treatment of drug abuse and addiction	ESTEVE PHARMACEUTICALS. S.A.	09/06/21	2D 3D TSV
US10927105	323	248	HGNC:17038	Pyrazole MAGL inhibitors	LUNDBECK LA JOLLA RESEARCH CENTER, INC.	09/06/21	2D 3D TSV
US10927086	86	48	HGNC:6059	Substituted sulfoximine compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors	Merck Sharp & Dohme Corp.	09/06/21	2D 3D TSV
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US10925840	52	26	HGNC:285 HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The USA, as represented by the Secretary, Department of Health and Human Services; SRI International	09/06/21	2D 3D TSV
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US10918640	19	18	HGNC:3553	Azetidine derivatives	Vernalis (R&D) Ltd.	09/02/21	2D 3D TSV
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US10919856	36	18		Cyclohexene compounds and use thereof	GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD.	09/02/21	2D 3D TSV
US10919862	9	6		Fused imidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	09/02/21	2D 3D TSV
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US10918642	68	68	HGNC:3255	N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors	Nerviano Medical Sciences S.R.L.	09/02/21	2D 3D TSV
US10919890	4	1	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	09/02/21	2D 3D TSV
US10919913	67	56	HGNC:6973	Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors	Boehringer Ingelheim International GmbH	09/02/21	2D 3D TSV
US10918645	91	51	HGNC:6192	Substituted tricyclic heterocyclic compounds and use thereof	LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.	09/02/21	2D 3D TSV
US10919869	50	49	HGNC:2867	Thiazole derivative and applications	EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY	09/02/21	2D 3D TSV
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US10919895	66	37	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	09/02/21	2D 3D TSV
US10919911	81	80	HGNC:6857	Tricyclic ASK1 inhibitors	TERNS, INC.	09/02/21	2D 3D TSV
US10913710	100	99	HGNC:8788	Benzene disulfonamide for the treatment of cancer	Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V	08/30/21	2D 3D TSV
US10913735	14	14	HGNC:11138	Bis-heteroaryl derivatives as modulators of protein aggregation	UCB Biopharma SRL	08/30/21	2D 3D TSV
US10912773	302	107	HGNC:8775 HGNC:8774 HGNC:8776	Combinations comprising substituted imidazo[1,5-a]pyrazinones as PDE1 inhibitors	H. Lundbeck A/S	08/30/21	2D 3D TSV
US10913740	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	Theravance Biopharma R&D IP, LLC	08/30/21	2D 3D TSV
US10913744	54	20		LRRK2 inhibitors and methods of making and using the same	DANA-FARBER CANCER INSTITUTE, INC.	08/30/21	2D 3D TSV
US10913745	49	47	HGNC:10548	Octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors	Hoffmann-La Roche Inc.	08/30/21	2D 3D TSV
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US10913711	189	59		Potent and selective inhibitors of monoamine transporters; method of making; and use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES	08/30/21	2D 3D TSV
US10912774	144	67	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	EISAI R&D MANAGEMENT CO., LTD.	08/30/21	2D 3D TSV
US10913746	124	111	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	The Trustees of Columbia University in the City of New York	08/30/21	2D 3D TSV
US10913733	54	50	HGNC:7056	Substituted piperidines thiazolyl acetamides as glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.	08/30/21	2D 3D TSV
US10913753	410	219		Thienopyridine carboxamides as ubiquitin-specific protease inhibitors	VALO EARLY DISCOVERY, INC.	08/30/21	2D 3D TSV
US10905688	302	111	HGNC:8775 HGNC:8774 HGNC:8776	Combinations comprising substituted imidazo[1,5-α]pyrazinones as PDE1 inhibitors	H. Lundbeck A/S	08/22/21	2D 3D TSV
US10906896	132	42	HGNC:77 HGNC:76 HGNC:6342	Compositions and methods for inhibiting kinases	Inhibikase Therapeutics, Inc.	08/22/21	2D 3D TSV
US10906900	62	14	HGNC:11138	Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)	08/22/21	2D 3D TSV
US10906905	88	52	HGNC:6307 HGNC:6876	Five-membered heteroaryl ring bridged ring derivative, preparation method therefor and medical use thereof	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/22/21	2D 3D TSV
US10906920	68	65		Heterocyclic compounds as immunomodulators	Incyte Corporation	08/22/21	2D 3D TSV
US10906878	7	7	HGNC:1133	Kinase inhibitors for the treatment of disease	DANA FARBER CANCER INSTITUTE, INC.	08/22/21	2D 3D TSV
US10906888	205	198		Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme	Pfizer Inc.	08/22/21	2D 3D TSV
US10905687	20	20		Substituted piperazines as ROR-gamma modulators	ESCALIER BIOSCIENCES B.V.	08/22/21	2D 3D TSV
US10906915	372	370	HGNC:8783	Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors	LEO Pharma A/S	08/22/21	2D 3D TSV
US10906890	112	103	HGNC:339	Triazole phenyl compounds as agonists of the APJ receptor	AMGEN INC.	08/22/21	2D 3D TSV
US10899772	34	34	HGNC:17967	IRAK4 modulators	Genentech, Inc.	08/16/21	2D 3D TSV
US10899774	71	71	HGNC:17967	IRAK4 modulators	Genentech, Inc.	08/16/21	2D 3D TSV
US10899741	9	4	HGNC:6307 HGNC:10020 HGNC:6876	3,4-bipyridyl pyrazole derivative, and preparation method therefor and medical application thereof	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/15/21	2D 3D TSV
US10899755	32	32	HGNC:6863	Benzothiazole compounds and uses thereof	Incyte Corporation	08/15/21	2D 3D TSV
US10899764	56	33	HGNC:11708 HGNC:6059	Imidazo isoindole derivative, preparation method therefor and medical use thereof	JIANGSU HENGRUI MEDICINE CO., LTD.; SHANGHAI HENGRUI PHRMACEUTICAL CO., LTD.	08/15/21	2D 3D TSV
US10899769	268	124		Imidazopiperazinone inhibitors of transcription activating proteins	Board of Regents, The University of Texas System	08/15/21	2D 3D TSV
US10899753	110	110	HGNC:1133	Inhibiting agents for Bruton's tyrosine kinase	BIOGEN MA INC.	08/15/21	2D 3D TSV
US10899735	432	427		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	08/15/21	2D 3D TSV
US10899756	28	23	HGNC:8784 HGNC:8785	Phosphodiesterase inhibitors and uses thereof	The Trustees of Columbia University in the City of New York	08/15/21	2D 3D TSV
US10899738	386	378	HGNC:7010	Piperidines as menin inhibitors	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	08/15/21	2D 3D TSV
US10898481	73	38	HGNC:262 HGNC:263 HGNC:264	Pyrazine compounds and uses thereof	TBA	08/15/21	2D 3D TSV
US10894048	73	49	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Antitumor drug for intermittent administration of FGFR inhibitor	Taiho Pharmaceutical Co., Ltd.	08/14/21	2D 3D TSV
US10894797	52	51	HGNC:9644	Fused tricyclic ring derivatives as SRC homology-2 phosphatase inhibitors	Nikang Therapeutics, Inc.	08/14/21	2D 3D TSV
US10894789	334	165	HGNC:4849 HGNC:4848	Halo-substituted piperidines as orexin receptor modulators	ASTRAZENECA AB; EOLAS THERAPEUTICS, INC.	08/14/21	2D 3D TSV
US10894784	652	648	HGNC:11584	Heteroarylbenzimidazole compounds	BAYER PHARMA AKTIENGESELLSCHAFT	08/14/21	2D 3D TSV
US10894052	36	35		Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	08/14/21	2D 3D TSV
US10894038	20	19	HGNC:17989	Indolizine derivatives, composition and methods of use	SHANGHAI FOCHON PHARMACEUTICAL CO. LTD.; FOCHON PHARMACEUTICALS, LTD.	08/14/21	2D 3D TSV
US10894788	199	161		Inhibitors of cyclin-dependent kinases	KINNATE BIOPHARMA INC.	08/14/21	2D 3D TSV
US10894782	132	120	HGNC:12666	Modulators of P97 AAA ATPase activity	University of Pittsburgh—Of the Commonwealth System of Higher Education	08/14/21	2D 3D TSV
US10894803	4	4	HGNC:5467	Multi-functionalized polysaccharide compounds and use thereof for targeting the cation-independent mannose 6-phosphate receptor	NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier	08/14/21	2D 3D TSV
US10894807	103	102	HGNC:3788	PSMA imaging agents	Siemens Medical Solutions USA, Inc.	08/14/21	2D 3D TSV
US10894794	3	3	HGNC:3009	Substituted [1,2,4]triazolo[4,3-a]pyrazines as antidiabetics	King Abdulaziz University	08/14/21	2D 3D TSV
US10894786	141	46	HGNC:1778 HGNC:1733	Substituted pyrazole derivatives as selective CDK12/13 inhibitors	Aurigene Discovery Technologies Limited	08/14/21	2D 3D TSV
US10889546	85	74	HGNC:1232 HGNC:14661	Alkynyl pyridine prolyl hydroxylase inhibitor, and preparation method and medical use thereof	Jiangsu Hengrui Medicine Co., Ltd.	08/09/21	2D 3D TSV
US10889610	25	22	HGNC:6561 HGNC:6563	Alpha-D-galactoside inhibitors of galectins	GALECTO BIOTECH AB	08/09/21	2D 3D TSV
US10889589	161	157	HGNC:8031	Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain	Array BioPharma Inc.	08/09/21	2D 3D TSV
US10888561	14	14	HGNC:9843	CGRP receptor antagonists	Heptares Therapeutics Limited	08/09/21	2D 3D TSV
US10889569	62	32	HGNC:897 HGNC:895 HGNC:896	Condensed ring group azacyclobutyl triazole derivative, preparation method therefor and use thereof in medicine	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/09/21	2D 3D TSV
US10889581	120	40	HGNC:934 HGNC:2529 HGNC:933	Cyclopropyl fused thiazine derivatives as beta-secretase inhibitors and methods of use	Amgen Inc.	08/09/21	2D 3D TSV
US10889552	29	29	HGNC:5253	Dihydroxybenzamide compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof	ONCOZEN CO.. LTD.	08/09/21	2D 3D TSV
US10889568	96	95	HGNC:12338	Inhibitors of TRPC6	Boehringer Ingelheim International GmbH	08/09/21	2D 3D TSV
US10888567	78	78	HGNC:6059	Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy	Auckland UniServices Limited	08/09/21	2D 3D TSV
US10889591	69	69	HGNC:8795	PDE9 inhibitor and use thereof	Nanjing TransThera Biosciences Co. Ltd.	08/09/21	2D 3D TSV
US10889571	217	215		Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias	Terns, Inc.	08/09/21	2D 3D TSV
US10889555	279	268		Sulfonamide compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	08/09/21	2D 3D TSV
US10889564	52	52	HGNC:2867	Tetrahydroindazoles and medical uses thereof	Genase Therapeutics B.V.	08/09/21	2D 3D TSV
US10889579	51	17	HGNC:934 HGNC:2529 HGNC:933	Thiazine derivatives as β-secretase inhibitors and methods of use	Amgen Inc.	08/09/21	2D 3D TSV
US10889592	39	21		Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors	VALO EARLY DISCOVERY, INC.	08/09/21	2D 3D TSV
US10889595	7	7	HGNC:933	[1,3]thiazin-2-amine compound, application, and pharmaceutical composition	TETRANOV PHARMACEUTICAL CO., LTD.	08/09/21	2D 3D TSV
US10888550	33	33	HGNC:6819	Pyrazole derivatives as MALT1 inhibitors	Janssen Pharmaceutica NV	08/08/21	2D 3D TSV
US10881668	12	6	HGNC:13575 HGNC:1105	Acetamide thienotriazolodiazepines and uses thereof	Dana-Farber Cancer Institute, Inc.	08/01/21	2D 3D TSV
US10882857	17	17	HGNC:3357	Bicyclic compounds as ATX inhibitors	Hoffmann-La Roche Inc.	08/01/21	2D 3D TSV
US10882838	177	61	HGNC:2160	Cannabinergic compounds and uses thereof	NORTHEASTERN UNIVERSITY	08/01/21	2D 3D TSV
US10882844	48	48		Compounds useful as immunomodulators	Bristol-Myers Squibb Company	08/01/21	2D 3D TSV
US10882835	27	27	HGNC:29079	KDM1A inhibitors for the treatment of disease	Imago Biosciences, Inc.	08/01/21	2D 3D TSV
US10882859	12	3	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Kinase inhibitors	TOPIVERT PHARMA LIMITED	08/01/21	2D 3D TSV
US10882829	88	22	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pharmaceutical compounds	Sareum Limited	08/01/21	2D 3D TSV
US10882833	17	16		Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	08/01/21	2D 3D TSV
US10882866	148	137		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	08/01/21	2D 3D TSV
US10881652	2116	812	HGNC:9967	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array Biopharma Inc.	08/01/21	2D 3D TSV
US10882855	56	19	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases	ONO PHARMACEUTICAL CO., LTD.	08/01/21	2D 3D TSV
US10882853	12	8	HGNC:6307 HGNC:7029	Tyrosine kinase inhibitor and application thereof	LaNova Medicines Limited	08/01/21	2D 3D TSV
US10870635	36	25	HGNC:934 HGNC:2529 HGNC:933	Compounds and their use as BACE1 inhibitors	ALLGENESIS BIOTHERAPEUTICS, INC.	07/26/21	2D 3D TSV
US10870651	52	40	HGNC:3697 HGNC:1780 HGNC:16870 HGNC:1771 HGNC:16627 HGNC:11283 HGNC:9410 HGNC:19007 HGNC:9967	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Dana-Farber Cancer Institute, Inc.	07/26/21	2D 3D TSV
US10870660	278	138	HGNC:3023 HGNC:3024	Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect	SHIONOGI & CO., LTD.	07/26/21	2D 3D TSV
US10870641	855	825		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics, Inc.	07/26/21	2D 3D TSV
US10870639	27	18	HGNC:3765	Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same	HANMI PHARM. CO.. LTD.	07/26/21	2D 3D TSV
US10870625	10	10	HGNC:2861	Zwitterionic propargyl-linked antifolates useful for treating bacterial infections	UNIVERSITY OF CONNECTICUT	07/26/21	2D 3D TSV
US10875847	13	9	HGNC:6190 HGNC:6192 HGNC:6193	Aminopyrazoles as selective janus kinase inhibitors	Intervet Inc.	07/25/21	2D 3D TSV
US10875829	6	2	HGNC:11050 HGNC:11048 HGNC:11049	Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission	INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB	07/25/21	2D 3D TSV
US10864192	4	4	HGNC:108	Compositions and methods for inhibiting brain trauma-induced neurodegeneration and related conditions	Aristea Translational Medicine Corporation	07/25/21	2D 3D TSV
US10869871	96	91	HGNC:5154	Compositions and methods of modulating short-chain dehydrogenase activity	CASE WESTERN RESERVE UNIVERSITY; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM	07/25/21	2D 3D TSV
US10874634	43	23	HGNC:20581 HGNC:2603	Compounds and methods for inhibiting CYP26 enzymes	Queen''s University at Kingston	07/25/21	2D 3D TSV
US10875867	202	90	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	07/25/21	2D 3D TSV
US10875851	183	174	HGNC:3530	Factor XIIa inhibitors	MERCK SHARP & DOHME CORP.	07/25/21	2D 3D TSV
US10875852	156	151	HGNC:1133	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	07/25/21	2D 3D TSV
US10874687	12	3		Highly active compounds against COVID-19	Atea Pharmaceuticals, Inc.	07/25/21	2D 3D TSV
US10870618	46	30	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors and uses thereof	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT	07/25/21	2D 3D TSV
US10874683	39	26		N4-hydroxycytidine and derivatives and anti-viral uses related thereto	Emory University	07/25/21	2D 3D TSV
US10874669	32	16	HGNC:3023 HGNC:3024	Neuroprotective agents for treatment of neurodegenerative diseases	WAYNE STATE UNIVERSITY	07/25/21	2D 3D TSV
US10869929	22	22		Phosphonate linkers and their use to facilitate cellular retention of compounds	MERCK SHARP & DOHME CORP.	07/25/21	2D 3D TSV
US10874675	34	34	HGNC:23357	Pteridine dione monocarboxylate transporter inhibitors	THE SCRIPPS RESEARCH INSTITUTE	07/25/21	2D 3D TSV
US10875863	26	25	HGNC:10020	RIPK2 inhibitors and method of treating cancer with same	UNIVERSITY HEALTH NETWORK	07/25/21	2D 3D TSV
US10875864	120	102	HGNC:6251	Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors	SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC.	07/25/21	2D 3D TSV
US10875832	3	3		Substituted pyrimidines for treating bacterial infections	FORGE THERAPEUTICS, INC.	07/25/21	2D 3D TSV
US10874640	138	136		Substituted pyrrolizine compounds and uses thereof	GILEAD SCIENCES, INC.	07/25/21	2D 3D TSV
US10875854	35	34		Triazolopyridines	Hoffmann-La Roche Inc.	07/25/21	2D 3D TSV
US10870623	23	23		Trifluoromethylpropanamide derivatives as HTRA1 inhibitors	Hoffmann-La Roche Inc.	07/25/21	2D 3D TSV
US10865384	119	47	HGNC:2453 HGNC:2452 HGNC:6876	2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis	Agency for Science, Technology and Research; National University of Singapore	07/18/21	2D 3D TSV
US10865208	231	229	HGNC:16935	ATG7 inhibitors and the uses thereof	MILLENNIUM PHARMACEUTICALS, INC.	07/18/21	2D 3D TSV
US10864248	3	3		Dab2 inhibitors for the prevention and treatment of cystic fibrosis	TRUSTEES OF DARTMOUTH COLLEGE	07/18/21	2D 3D TSV
US10865182	17	17		Difluoroketamide derivatives as HtrA1 inhibitors	Hoffmann-La Roche Inc.	07/18/21	2D 3D TSV
US10864201	57	57		Heteroaromatic compounds as Vanin inhibitors	Boehringer Ingelheim International GmbH	07/18/21	2D 3D TSV
US10865206	15	15	HGNC:1778	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Syros Pharmaceuticals, Inc.	07/18/21	2D 3D TSV
US10864202	75	75	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	07/18/21	2D 3D TSV
US10865186	25	12	HGNC:8154 HGNC:8156	Opioid agonists and uses thereof	Nektar Therapeutics	07/18/21	2D 3D TSV
US10865195	7	7	HGNC:10548	Pet imaging agents	Novartis AG	07/18/21	2D 3D TSV
US10851050	39	39		Biaryl urea derivative or salt thereof and preparation process and use for the same	FUDAN UNIVERSITY	07/13/21	2D 3D TSV
US10849881	117	116	HGNC:10548	Octahydro-cyclobuta[1,2-c;3,4-c′]dipyrrol-2-yl	Hoffmann-La Roche Inc.	07/13/21	2D 3D TSV
US10849901	159	140		Arf6 inhibitors and methods of synthesis and use thereof	Navigen, Inc.; The University of Utah Research Foundation	07/12/21	2D 3D TSV
US10851083	186	185		Benzoimidazoles as prolyl hydroxylase inhibitors	Janssen Pharmaceutica NV	07/12/21	2D 3D TSV
US10849883	380	377	HGNC:2771	Benzopyrazole compounds and analogues thereof	BioCryst Pharmaceuticals, Inc.	07/12/21	2D 3D TSV
US10851091	62	21	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Benzoxazepin oxazolidinone compounds and methods of use	Genentech, Inc.	07/12/21	2D 3D TSV
US10851116	188	43	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Bicyclic amines as novel JAK kinase inhibitors	LEO Pharma A/S	07/12/21	2D 3D TSV
US10851105	96	12	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	07/12/21	2D 3D TSV
US10849982	64	64	HGNC:2717	C3-carbon linked glutarimide degronimers for target protein degradation	C4 Therapeutics, Inc.	07/12/21	2D 3D TSV
US10851110	95	92		Heterocyclic inhibitors of PTPN11	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	07/12/21	2D 3D TSV
US10851102	162	52	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Imidazole and triazole containing bicyclic compounds as JAK inhibitors	Theravance Biopharma R&D IP, LLC	07/12/21	2D 3D TSV
US10851089	32	30	HGNC:7158	Matrix metalloproteinase (MMP) inhibitors and methods of use thereof	Foresee Pharmaceuticals Co., Ltd.	07/12/21	2D 3D TSV
US10851080	31	31	HGNC:8031	Methods of treatment using pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds	Array Biopharma Inc.	07/12/21	2D 3D TSV
US10851092	6	3	HGNC:9967	Pyridine compound	Daiichi Sankyo Company, Limited	07/12/21	2D 3D TSV
US10851082	434	227	HGNC:7110 HGNC:7111	Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2)	Northwestern University	07/12/21	2D 3D TSV
US10851108	7	7	HGNC:6255	Substituted bicyclic heterocyclic compounds	Bristol-Myers Squibb Company	07/12/21	2D 3D TSV
US10849898	122	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas	CELGENE QUANTICEL RESEARCH, INC.	07/12/21	2D 3D TSV
US10858342	226	112	HGNC:2592 HGNC:2591	Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases	Boehringer Ingelheim International GmbH	07/11/21	2D 3D TSV
US10857082	27	26		Diarylalkanes as potent inhibitors of binuclear enzymes	Unigen, Inc.	07/11/21	2D 3D TSV
US10858323	12	3	HGNC:4852 HGNC:14064 HGNC:4854 HGNC:4853	HDAC inhibitors for the treatment of diabetic peripheral neuropathy	REGENACY PHARMACEUTICALS, LLC	07/11/21	2D 3D TSV
US10858359	6	6	HGNC:9644	Heterocyclic ring derivatives useful as SHP2 inhibitors	JACOBIO PHARMACEUTICALS CO., LTD.	07/11/21	2D 3D TSV
US10858373	106	53	HGNC:17038	Heterocyclic spiro compounds as MAGL inhibitors	Pfizer Inc.	07/11/21	2D 3D TSV
US10858344	20	20	HGNC:3078	Hydantoin containing deoxyuridine triphosphatase inhibitors	CV6 Therapeutics (NI) Limited	07/11/21	2D 3D TSV
US10858364	15	3	HGNC:3432 HGNC:3430 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:11719 HGNC:12434 HGNC:3236	Imidazopyrazine inhibitors of Bruton's tyrosine kinase	Acerta Pharma B.V.	07/11/21	2D 3D TSV
US10858362	311	111	HGNC:8775 HGNC:8774 HGNC:8776	Imidazopyrazinones as PDE1 inhibitors	H. Lundbeck A/S	07/11/21	2D 3D TSV
US10858355	37	34	HGNC:8978	Inhibitors of phosphatidylinositol 3-kinase gamma	AstraZeneca AB	07/11/21	2D 3D TSV
US10858368	22	22	HGNC:5302	Modulators of the 5-hydroxytryptamine receptor 7 and their method of use	TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION; PRAEVENTIX, LLC	07/11/21	2D 3D TSV
US10858326	5	5	HGNC:17734	Oxazoline pseudodimers, pharmaceutical compositions and the use thereof	PURDUE PHARMA L.P.	07/11/21	2D 3D TSV
US10858356	80	80	HGNC:4324	Pyrazolopyridine derivative having GLP-1 receptor agonist effect	Chugai Seiyaku Kabushiki Kaisha	07/11/21	2D 3D TSV
US10858316	146	98	HGNC:6943	Small molecule inhibitors of the MCL-1 oncoprotein and uses thereof	UNIVERSITY OF MARYLAND, BALTIMORE	07/11/21	2D 3D TSV
US10858365	518	119	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Triazolo-pyrimidine compounds and uses thereof	TBA	07/11/21	2D 3D TSV
US10858366	71	41		Tricyclic compounds useful to treat orthomyxovirus infections	Novartis AG	07/11/21	2D 3D TSV
US10844038	134	16	HGNC:11283 HGNC:8980 HGNC:8979 HGNC:6877 HGNC:8978 HGNC:6735 HGNC:4037 HGNC:6871 HGNC:3942 HGNC:8977 HGNC:9967 HGNC:3765 HGNC:6171 HGNC:11393 HGNC:12841 HGNC:9617 HGNC:3432 HGNC:6844 HGNC:4840 HGNC:3697 HGNC:6845 HGNC:1079 HGNC:6846 HGNC:1057 HGNC:1133 HGNC:6847 HGNC:16627 HGNC:1097 HGNC:6342 HGNC:3955 HGNC:6840 HGNC:2444 HGNC:6842 HGNC:6524 HGNC:6843	1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions	SABILA BIOSCIENCES LLC	07/06/21	2D 3D TSV
US10844056	73	63	HGNC:5253	Fused amino pyridine as HSP90 inhibitors	Curis, Inc.	07/06/21	2D 3D TSV
US10844067	255	86	HGNC:6307 HGNC:9967	Heterocyclic compounds as RET kinase inhibitors	Cancer Research Technology Limited	07/06/21	2D 3D TSV
US10842803	100	100	HGNC:11491	Imidazopyridines Syk inhibitors	KRONOS BIO, INC.	07/06/21	2D 3D TSV
US10844057	52	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Process for preparing JAK inhibitors and intermediates thereof	Theravance Biopharma R&D IP, LLC	07/06/21	2D 3D TSV
US10844062	94	92	HGNC:6307	Pyridine derivative inhibiting RAF kinase and vascular endothelial growth factor receptor, method for preparing same, pharmaceutical composition containing same, and use thereof	Incheon University Industry Academic Cooperation Foundation; Samjin Pharmaceutical Co., Ltd.; Bamichem Co., Ltd.	07/06/21	2D 3D TSV
US10844069	438	146	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as TAM inhibitors	Incyte Corporation	07/06/21	2D 3D TSV
US10842799	110	107	HGNC:6871	Serine/threonine kinase inhibitors	GENENTECH, INC.	07/06/21	2D 3D TSV
US10844032	286	271	HGNC:990	Substituted benzofuran, benzothiophene and indole Mcl-1 inhibitors	Vanderbilt University	07/06/21	2D 3D TSV
US10844077	44	22	HGNC:4840 HGNC:1133	Thiazolyl-containing compounds for treating proliferative diseases	Dana-Farber Cancer Institute, Inc.	07/06/21	2D 3D TSV
US10844044	364	359	HGNC:12757	WDR5 inhibitors and modulators	Vanderbilt University	07/06/21	2D 3D TSV
US10836763	48	12	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	5 to 7 membered heterocyclic amides as JAK inhibitors	Theravance Biopharma R&D IP, LLC	06/30/21	2D 3D TSV
US10836764	164	55	HGNC:5295 HGNC:5294	5-HT2C receptor agonists and compositions and methods of use	Arena Pharmaceuticals, Inc.	06/30/21	2D 3D TSV
US10836773	6	6	HGNC:7056	6-fluoro-2-methylbenzo[d]thiazol-5-yl compounds	Eli Lilly and Company	06/30/21	2D 3D TSV
US10836758	75	73	HGNC:10597	Acyl sulfonamide NaV1.7 inhibitors	BRISTOL-MYERS SQUIBB COMPANY	06/30/21	2D 3D TSV
US10829489	98	57	HGNC:8810	Bicyclic heterocyclic derivatives	Merck Patent GmbH	06/30/21	2D 3D TSV
US10836743	110	58	HGNC:6833 HGNC:6834 HGNC:29079	Fluorinated cyclopropylamine compound, preparation method therefor, pharmaceutical composition thereof, and uses thereof	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	06/30/21	2D 3D TSV
US10836720	24	13	HGNC:6153	Inhibitors of integrin alpha 5 beta 1 and methods of use	The Regents of the University of California	06/30/21	2D 3D TSV
US10836768	205	47	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Ogeda SA	06/30/21	2D 3D TSV
US10836742	15	15		N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals	Neomed Institute	06/30/21	2D 3D TSV
US10836741	13	12		Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	Valo Early Discovery, Inc.	06/30/21	2D 3D TSV
US10836728	22	11	HGNC:711 HGNC:8156	Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same	Mebias Discovery, Inc.	06/30/21	2D 3D TSV
US10836769	56	55		Substituted pyrrolizine compounds and uses thereof	GILEAD SCIENCES, INC.	06/30/21	2D 3D TSV
US10835536	52	50	HGNC:3689	Therapeutic agent for FGFR inhibitor-resistant cancer	Taiho Pharmaceutical Co., Ltd.	06/30/21	2D 3D TSV
US10829488	46	22		N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	06/29/21	2D 3D TSV
US10828301	51	51	HGNC:11491	2,4-pyrimidinediamine compounds and their uses	Rigel Pharmceuticals, Inc.	06/28/21	2D 3D TSV
US10829480	296	153	HGNC:8155 HGNC:8156	3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives	GRUENENTHAL GMBH	06/28/21	2D 3D TSV
US10829478	698	150	HGNC:7160 HGNC:195 HGNC:7159 HGNC:220 HGNC:221	5-[3-[piperazin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating e.g. osteoarthritis	GALAPAGOS NV	06/28/21	2D 3D TSV
US10829492	73	50	HGNC:6192 HGNC:8031 HGNC:8032 HGNC:8033	Amino pyrazolopyrimidine compound used as neurotrophic factor tyrosine kinase receptor inhibitor	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	06/28/21	2D 3D TSV
US10829446	156	155		Aryl sulfonohydrazides	MONASH UNIVERSITY; The Walter and Eliza Hall Institute of Medical Research	06/28/21	2D 3D TSV
US10829481	189	189		Benzimidazole derivatives as modulators of ROR-gamma	Vitae Pharmaceuticals, LLC	06/28/21	2D 3D TSV
US10829487	150	149		Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors	Boehringer Ingelheim International GmbH	06/28/21	2D 3D TSV
US10829493	69	23	HGNC:6342	Compositions and methods for treating KIT- and PDGFRA-mediated diseases	Blueprint Medicines Corporation	06/28/21	2D 3D TSV
US10828299	7	7	HGNC:11491	Crystalline monomesylate salt of 6-(6-aminopyrazin-2-yl)-n-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine	KRONOS BIO, INC.	06/28/21	2D 3D TSV
US10829438	7	7		Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	06/28/21	2D 3D TSV
US10829500	5	5	HGNC:933	Pyridyl-triazabicycles	Hoffmann-La Roche Inc.	06/28/21	2D 3D TSV
US10829502	125	82	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Corporation; Incyte Holdings Corporation	06/28/21	2D 3D TSV
US10829491	22	22	HGNC:1133	Pyrimido[5,4-B]indolizine or pyrimido[5,4-B]pyrrolizine compound, preparation method and use thereof	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACAD	06/28/21	2D 3D TSV
US10828300	248	244	HGNC:1133	Substituted 2,4-diaminopyrimidines as kinase inhibitors	Celgene CAR LLC	06/28/21	2D 3D TSV
US10829448	121	111		Substituted benzoimidazoles as modulators of ROR-γ	Vitae Pharmaceuticals, LLC	06/28/21	2D 3D TSV
US10829490	71	9	HGNC:1780 HGNC:1771 HGNC:1777 HGNC:1774 HGNC:1773 HGNC:1775	Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents	GI Therapeutics, Inc.	06/28/21	2D 3D TSV
US10828290	327	108	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors	Incyte Corporation; Incyte Holdings Corporation	06/28/21	2D 3D TSV
US10829496	29	27	HGNC:17967	Thienopyridines and benzothiophenes useful as IRAK4 inhibitors	Bristol-Myers Squibb Company	06/28/21	2D 3D TSV
US10829483	103	103	HGNC:17989	Thiophene, manufacturing method thereof, and pharmaceutical application of same	CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD.; CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD.; CSTONE PHARMACEUTICALS	06/28/21	2D 3D TSV
US10822352	718	703	HGNC:2771	Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	06/21/21	2D 3D TSV
US10822319	2	2		Crystal of DPP-IV long-acting inhibitor and salt	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.	06/21/21	2D 3D TSV
US10822334	60	30	HGNC:3430 HGNC:3236	ErbB receptor inhibitors	TBA	06/21/21	2D 3D TSV
US10822348	937	789		Inhibitors of Bruton's tyrosine kinase and methods of their use	Janssen Pharmaceutica NV	06/21/21	2D 3D TSV
US10822345	64	63	HGNC:6221	KV1.3 inhibitors and their medical application	4SC AG	06/21/21	2D 3D TSV
US10822331	4	1	HGNC:882	Processes for preparing ATR inhibitors	VERTEX PHARMACEUTICALS INCORPORATED	06/21/21	2D 3D TSV
US10822341	148	37	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolo[1,5-a]pyrazin-4-yl derivatives	Pfizer Inc.	06/21/21	2D 3D TSV
US10822342	12	12	HGNC:6853	Pyrazolopyrimidine derivatives as NIK inhibitors	Janssen Pharmaceutica NV	06/21/21	2D 3D TSV
US10822338	75	74	HGNC:263	Substituted aminoquinazoline compounds as A2A antagonist	Merck Sharp & Dohme Corp.	06/21/21	2D 3D TSV
US10821115	969	797		Compounds that inhibit Mcl-1 protein	AMGEN INC.	06/20/21	2D 3D TSV
US10815234	116	115		Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	06/14/21	2D 3D TSV
US10815244	10	10	HGNC:3236	Isoidide derivatives and methods of making and using same	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	06/14/21	2D 3D TSV
US10815241	10	10	HGNC:7010	Optically active azabicyclo ring derivative	Sumitomo Dainippon Pharma Co., Ltd.	06/14/21	2D 3D TSV
US10813932	120	31	HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:20790 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors	Respivert Limited	06/13/21	2D 3D TSV
US10815215	268	215	HGNC:2867	2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH	BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION	06/13/21	2D 3D TSV
US10815229	1146	325	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	06/13/21	2D 3D TSV
US10815213	190	140	HGNC:1133 HGNC:3236	Bruton's tyrosine kinase inhibitors	Pfizer Inc.	06/13/21	2D 3D TSV
US10815208	4	4		Method for preparing 2-hydroxyl-4-(2, 3-disubstituted benzyloxy)-5-substituted benzaldehyde derivative	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	06/13/21	2D 3D TSV
US10815206	95	90		RIP1 inhibitory compounds and methods for making and using the same	Rigel Pharmaceuticals, Inc.	06/13/21	2D 3D TSV
US10813930	107	107	HGNC:3690	Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3	Incyte Corporation; Incyte Holdings Corporation	06/13/21	2D 3D TSV
US10813942	17	17	HGNC:742	Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR	Pfizer Inc.	06/13/21	2D 3D TSV
US10806718	605	192	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	06/11/21	2D 3D TSV
US10807988	790	396	HGNC:8155 HGNC:8156	3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	Grünenthal GmbH	06/11/21	2D 3D TSV
US10807989	571	289	HGNC:8155 HGNC:8156	3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRÜNENTHAL GMBH	06/11/21	2D 3D TSV
US10807982	105	104	HGNC:13575	Bromodomain inhibitors	Celgene Quanticel Research, Inc.	06/11/21	2D 3D TSV
US10806724	59	59	HGNC:4594	Chromane, isochromane and dihydroisobenzofuran derivatives as mGluR2-negative allosteric modulators, compositions, and their use	Merck Sharp & Dohme Corp.	06/11/21	2D 3D TSV
US10807985	169	124		Compositions useful for treating disorders related to kit	Blueprint Medicines Corporation	06/11/21	2D 3D TSV
US10807952	101	101	HGNC:2771	Compounds for treatment of immune inflammatory disorders	Achillion Pharmaceuticals, Inc.	06/11/21	2D 3D TSV
US10807993	63	51	HGNC:6251	Dihydrochromene derivatives	Sumitomo Dainippon Pharma Co., Ltd.	06/11/21	2D 3D TSV
US10807980	220	156		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	06/11/21	2D 3D TSV
US10807986	522	200	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	06/11/21	2D 3D TSV
US10807944	144	42	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853	HDAC inhibitor compounds and methods of treatment	University of Florida Research Foundation, Inc.; The Scripps Research Institute	06/11/21	2D 3D TSV
US10807994	99	97	HGNC:12761	Heterocyclic compounds and uses thereof	NUVATION BIO INC.	06/11/21	2D 3D TSV
US10807966	27	16	HGNC:10251 HGNC:10252	Heterocyclic compounds as kinase inhibitors	Translational Drug Development, LLC	06/11/21	2D 3D TSV
US10807956	210	101	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	06/11/21	2D 3D TSV
US10806785	205	191		Immunomodulator compounds and methods of use	Incyte Corporation	06/11/21	2D 3D TSV
US10807974	309	161	HGNC:6833 HGNC:6834 HGNC:80 HGNC:6666	Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer	The Institute of Cancer Research: Royal Cancer Hospital	06/11/21	2D 3D TSV
US10806794	28	28		Protease inhibitors having enhanced features	Nektar Therapeutics	06/11/21	2D 3D TSV
US10807971	68	17	HGNC:16672 HGNC:3009	Pyrrolidinone compounds	Eli Lilly and Company	06/11/21	2D 3D TSV
US10806720	76	51	HGNC:644	Selective androgen receptor degrader (SARD) ligands and methods of use thereof	University of Tennessee Research Foundation	06/11/21	2D 3D TSV
US10807991	122	42	HGNC:3167 HGNC:3165 HGNC:14299	Spiro-cyclic amine derivatives as S1P modulators	AbbVie B.V.; AbbVie, Inc.	06/11/21	2D 3D TSV
US10807959	266	260	HGNC:12757	WDR5-MLL1 inhibitors and modulators	Vanderbilt University	06/11/21	2D 3D TSV
US10800755	217	38	HGNC:3023 HGNC:5286 HGNC:6251	2,6-disubstituted pyridine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	06/01/21	2D 3D TSV
US10800739	37	20	HGNC:270 HGNC:272	4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors	NERVIANO MEDICAL SCIENCES S.R.L.	06/01/21	2D 3D TSV
US10799507	607	155	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5-azaspiro[2.5]octane-8-carboxylic acid derivatives as novel JAK kinase inhibitors	Leo Pharma A/S	06/01/21	2D 3D TSV
US10800725	60	20		Arylpropionyl-triketone antibacterial agents	TBA	06/01/21	2D 3D TSV
US10800778	120	40		Beta-lactamase inhibitor compounds	Entasis Therapeutics Limited	06/01/21	2D 3D TSV
US10800786	33	32	HGNC:10548	Bicyclic compounds as ATX inhibitors	Hoffman-La Roche Inc.	06/01/21	2D 3D TSV
US10800783	433	218	HGNC:1771	CDK2/4/6 inhibitors	Pfizer Inc.	06/01/21	2D 3D TSV
US10800761	113	105	HGNC:6863	Carboxamide compounds and uses thereof	Incyte Corporation	06/01/21	2D 3D TSV
US10799494	22	22		Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor	TBA	06/01/21	2D 3D TSV
US10799605	13	7	HGNC:8039	Conjugate comprising a neurotensin receptor ligand and use thereof	3B Pharmaceuticals GMBH	06/01/21	2D 3D TSV
US10800776	45	25	HGNC:4594 HGNC:6251	Fluorine-containing triazolopyridine, and manufacturing method, pharmaceutical composition, and application thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	06/01/21	2D 3D TSV
US10800779	138	138	HGNC:29079	Heterocyclic compounds as LSD1 inhibitors	Incyte Corporation	06/01/21	2D 3D TSV
US10800768	271	266		Heterocyclic compounds as immunomodulators	Incyte Corporation	06/01/21	2D 3D TSV
US10800769	265	122	HGNC:1925	Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	06/01/21	2D 3D TSV
US10800774	64	32	HGNC:1925	Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	06/01/21	2D 3D TSV
US10800804	26	12	HGNC:6561 HGNC:6563	Hybrid galactoside inhibitor of galectins	TBA	06/01/21	2D 3D TSV
US10800744	41	41	HGNC:3827	Imidazole derivatives as formyl peptide receptor modulators	ALLERGAN, INC.	06/01/21	2D 3D TSV
US10800765	63	62	HGNC:4502	Indole derivative used as CRTH2 inhibitor	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.	06/01/21	2D 3D TSV
US10800792	937	912	HGNC:1133	Inhibitors of Bruton's tyrosine kinase and method of their use	Janssen Pharmaceutica NV	06/01/21	2D 3D TSV
US10800757	96	94	HGNC:12338	Inhibitors of TRPC6	Boehringer Ingelheim International GmbH; Hydra Biosciences, LLC	06/01/21	2D 3D TSV
USRE48253	9	9	HGNC:12576	Methotrexate adjuvants to reduce toxicity and methods for using the same	Tosk, Inc.	06/01/21	2D 3D TSV
US10800784	246	123	HGNC:8809 HGNC:8810	Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof	JAPAN TOBACCO INC.	06/01/21	2D 3D TSV
US10800746	22	11	HGNC:897 HGNC:895	Oxoalkyl-substituted phenyltriazole derivatives and uses thereof	BAYER PHARMA AKTIENGESELLSCHAFT	06/01/21	2D 3D TSV
US10800775	14	7	HGNC:6190	Pyrazolyl pyrrolo[2,3-b]pyrmidine-5-carboxylate analogs and methods of making the same	ACLARIS THERAPEUTICS, INC.	06/01/21	2D 3D TSV
US10800764	23	6		Substituted pyridine derivatives useful as C-FMS kinase inhibitors	Janssen Pharmaceutica NV	06/01/21	2D 3D TSV
US10800785	97	85	HGNC:1133	Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors	Shanghai Fochon Pharmaceutical Co., Ltd.; Fochon Pharmaceuticals, Ltd.	06/01/21	2D 3D TSV
US10800753	7	7	HGNC:23	Tetrahydrothiophene-based GABA aminotransferase inactivators and analogs thereof for treating neurological disorders	Northwestern University	06/01/21	2D 3D TSV
US10800767	82	36	HGNC:11799 HGNC:11796	Thyroid hormone receptor beta agonist compounds	Terns, Inc.	06/01/21	2D 3D TSV
US10799518	188	179	HGNC:3827	Use of agonists of formyl peptide receptor 2 for treating dermatological diseases	ALLERGAN, INC.	06/01/21	2D 3D TSV
US10793561	2	2	HGNC:262	1,8-naphthyridinone compounds and uses thereof	NUVATION BIO INC.	05/14/21	2D 3D TSV
US10793528	150	75	HGNC:8156	3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRÜNENTHAL GMBH	05/14/21	2D 3D TSV
US10793556	178	34	HGNC:8155 HGNC:8156	8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRUENENTHAL GMBH	05/14/21	2D 3D TSV
US10793564	145	144	HGNC:6161	Amino acid compounds and methods of use	PLIANT THERAPEUTICS, INC.	05/14/21	2D 3D TSV
US10793552	3	3	HGNC:550	Amino pyrimidine ssao inhibitors	ELI LILLY AND COMPANY	05/14/21	2D 3D TSV
US10793582	85	84	HGNC:17929	Bicyclic heterocyclic compound	MITSUBISHI TANABE PHARMA CORPORATION	05/14/21	2D 3D TSV
US10793567	30	15	HGNC:4852 HGNC:4853	Bicyclic inhibitors of histone deacetylase	Rodin Therapeutics, Inc.	05/14/21	2D 3D TSV
US10793579	370	361	HGNC:17967	Bicyclic-fused heteroaryl or aryl compounds	Pfizer Inc.	05/14/21	2D 3D TSV
US10793566	134	123	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	05/14/21	2D 3D TSV
US10793576	128	126	HGNC:1133	Compound used as Bruton's tyrosine kinase inhibitor and preparation method and application thereof	CHENGDU BRILLIANT PHARMACEUTICAL CO., LTD.; CHENGDU HIGHBRED PHARMACEUTICAL CO., LTD.	05/14/21	2D 3D TSV
US10793563	532	502	HGNC:19687	GCN2 inhibitors and uses thereof	MERCK PATENT GMBH; VERTEX PHARMACEUTICALS INCORPORATED	05/14/21	2D 3D TSV
US10793514	38	19	HGNC:10943	Glutamine transport inhibitors and methods for treating cancer	Vanderbilt University	05/14/21	2D 3D TSV
US10793565	4	4		Heterocyclic compounds as immunomodulators	Incyte Corporation	05/14/21	2D 3D TSV
US10793535	51	45		Heterocyclic glutaminase inhibitors	Calithera Biosciences, Inc.	05/14/21	2D 3D TSV
US10793568	340	336	HGNC:7967	Hormone receptor modulators for treating metabolic conditions and disorders	ARDELYX, INC.	05/14/21	2D 3D TSV
US10793575	89	59	HGNC:1133	Oxoisoquinoline derivatives	CARNA BIOSCIENCES, INC.	05/14/21	2D 3D TSV
US10792283	7	7	HGNC:8977	Quinoline analogs as phosphatidylinositol 3-kinase inhibitors	HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD.	05/14/21	2D 3D TSV
US10793545	22	22	HGNC:17967	Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs	Bayer Pharma Aktiengesellschaft	05/14/21	2D 3D TSV
US10793591	16	15		Substituted nucleosides, nucleotides and analogs thereof	Janssen BioPharma, Inc.	05/14/21	2D 3D TSV
US10793580	310	310	HGNC:8783	Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors	LEO Pharma A/S	05/14/21	2D 3D TSV
US10793529	4	4	HGNC:9602	Substituted pyridazines and 1,2,4-triazines as prostacyclin receptor modulators	ARENA PHARMACEUTICALS, INC.	05/14/21	2D 3D TSV
US10793549	63	59		Sulfuryl-substituted benzoheterocyclic derivative, preparation method and medical use thereof	SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD.; YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.	05/14/21	2D 3D TSV
US10793574	218	217		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	05/14/21	2D 3D TSV
US10787452	579	555	HGNC:882	Compounds useful as inhibitors of ATR kinase	VERTEX PHARMACEUTICALS INCORPORATED	05/11/21	2D 3D TSV
US10787435	57	56	HGNC:6857	ASK1 inhibitor and preparation method and use thereof	Fuijan Cosunter Pharmaceutical Co. Ltd.	05/09/21	2D 3D TSV
US10787434	9	9	HGNC:10894	Benzopiperdine derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY, LTD	05/09/21	2D 3D TSV
US10787459	13	3	HGNC:10548	Bicyclic compounds as ATX inhibitors	Hoffmann-La Roche Inc.	05/09/21	2D 3D TSV
US10787419	92	90		Cannabinoid receptor mediating iminopyrazole compounds	The United States of America, as represented by the Secretary, Department of Health and Human Services	05/09/21	2D 3D TSV
US10787457	78	78	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	05/09/21	2D 3D TSV
US10787436	82	40	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:6881 HGNC:1722 HGNC:6112 HGNC:6850 HGNC:1779 HGNC:1774 HGNC:6886	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Dana-Farber Cancer Institute, Inc.	05/09/21	2D 3D TSV
US10787453	2	2	HGNC:9922	Octahydropyrrolopyrroles their preparation and use	The Trustees of Columbia University in the City of New York	05/09/21	2D 3D TSV
US10787472	23	23	HGNC:10582	Prodrugs of pyridone amides useful as modulators of sodium channels	Vertex Pharmaceuticals Incorporated	05/09/21	2D 3D TSV
US10787450	255	253	HGNC:10252	Spiro-fused cyclic ureas as inhibitors of rock	Bristol-Myers Squibb Company	05/09/21	2D 3D TSV
US10787438	40	18		Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors	Pfizer Inc.	05/09/21	2D 3D TSV
US10787425	105	105	HGNC:5154	Thiazolidinedione derivative and use thereof	INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY	05/09/21	2D 3D TSV
US10781209	196	93	HGNC:13575	1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	05/03/21	2D 3D TSV
US10781212	4	2		2,6-diamino pyridine compounds	Eli Lilly and Company	05/03/21	2D 3D TSV
US10781180	4	4		3-phenyl-pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals, Inc.	05/03/21	2D 3D TSV
US10781202	10	10	HGNC:8781	Azetidinyloxyphenylpyrrolidine compounds	Eli Lilly and Company	05/03/21	2D 3D TSV
US10781182	12	6	HGNC:7463	Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders	ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A.	05/03/21	2D 3D TSV
US10781185	149	108	HGNC:17270	Heterocyclic compounds for the inhibition of PASK	BioEnergenix LLC	05/03/21	2D 3D TSV
US10781181	216	108	HGNC:6371 HGNC:6357	N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	KALVISTA PHARMACEUTICALS LIMITED	05/03/21	2D 3D TSV
US10781211	677	260	HGNC:17038	Spirocycle compounds and methods of making and using same	LUNDBECK LA JOLLA RESEARCH CENTER, INC.	05/03/21	2D 3D TSV
US10781204	378	163	HGNC:6192 HGNC:12440	TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	05/03/21	2D 3D TSV
US10781200	140	137	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	05/03/21	2D 3D TSV
US10780095	30	25	HGNC:15836	Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	05/02/21	2D 3D TSV
US10780092	156	151	HGNC:4685	Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators	Merck Sharp & Dohme Corp.	05/02/21	2D 3D TSV
US10780090	537	352	HGNC:30660	Heteroaryl compounds useful as inhibitors of SUMO activating enzyme	Millennium Pharmaceuticals, Inc.	05/02/21	2D 3D TSV
US10780082	18	3	HGNC:427	Macrocycle and composition comprising thereof	Shenzhen TargetRx, Inc.	05/02/21	2D 3D TSV
US10780078	21	7	HGNC:8153 HGNC:8155 HGNC:8156	Mu opioid receptor modulators	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FRIEDRICH-ALEXANDER-UNIVERSITÄT; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY	05/02/21	2D 3D TSV
US10781171	288	287	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Epics Therapeutics	05/02/21	2D 3D TSV
US10766893	768	242	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	04/26/21	2D 3D TSV
US10766881	246	83		2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases	Array Biopharma Inc.	04/26/21	2D 3D TSV
US10766883	18	9	HGNC:6190 HGNC:6192	Aminopyrazoles as janus kinase inhibitors	Merck Sharp & Dohme Corp.	04/26/21	2D 3D TSV
US10766894	52	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aza-indazole compounds for use in tendon and/or ligament injuries	NOVARTIS AG	04/26/21	2D 3D TSV
US10766884	294	137	HGNC:1773	Cyclin dependent kinase inhibitors	Pfizer Inc.	04/26/21	2D 3D TSV
US10766897	213	155	HGNC:6251 HGNC:550	Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors	PROXIMAGEN, LLC	04/26/21	2D 3D TSV
US10766864	106	106	HGNC:8156	Morphinan derivatives for the treatment of neuropathic pain	Nektar Therapeutics	04/26/21	2D 3D TSV
US10766903	245	243	HGNC:12630	Piperidine derivatives as inhibitors of ubiquitin specific protease 7	ALMAC DISCOVERY LIMITED	04/26/21	2D 3D TSV
US10766858	25	19	HGNC:10597	Substituted benzamides and methods of use thereof	GENENTECH, INC.; XENON PHARMACEUTICALS INC.	04/26/21	2D 3D TSV
US10766878	63	33	HGNC:497	Sulfonylcycloalkyl carboxamide compounds	Genentech, Inc.	04/26/21	2D 3D TSV
US10765676	43	43	HGNC:8031	Trk-inhibiting compound	ONO PHARMACEUTICAL CO., LTD.	04/26/21	2D 3D TSV
US10766902	96	96	HGNC:12761	Wee-1 inhibiting pyrazolopyrimidinone compounds	ALMAC DISCOVERY LIMITED	04/26/21	2D 3D TSV
US10774065	22	22	HGNC:9644	1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2	NOVARTIS AG	04/25/21	2D 3D TSV
US10772893	488	432		2-(morpholin-4-yl)-1,7-naphthyridines	BAYER PHARMA AKTIENGESELLSCHAFT	04/25/21	2D 3D TSV
US10774070	79	39	HGNC:9967	2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors	BLUEPRINT MEDICINES CORPORATION	04/25/21	2D 3D TSV
US10774051	1232	1204	HGNC:8537	6-membered heterocyclic derivatives and pharmaceutical composition comprising the same	SHIONOGI & CO., LTD.	04/25/21	2D 3D TSV
US10774068	200	123	HGNC:11408 HGNC:11406	Composition and methods for inhibiting mammalian sterile 20-like kinase 1	THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN	04/25/21	2D 3D TSV
US10774069	4	3	HGNC:6666	Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making	PHARMAKEA, INC.	04/25/21	2D 3D TSV
US10774054	16	8	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774102	106	106	HGNC:6563	Galactoside inhibitor of galectins	Galecto Biotech AB	04/25/21	2D 3D TSV
US10774053	706	352		HIV protease inhibitors	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774052	194	191	HGNC:3691	Heteroaryl compounds and uses thereof	Celgene CAR LLC; Sanofi	04/25/21	2D 3D TSV
US10752635	54	54	HGNC:6863	Indazole compounds and uses thereof	Incyte Corporation	04/25/21	2D 3D TSV
US10774063	26	24	HGNC:10289	Materials and method for inhibiting replication protein A and uses thereof	Indiana University Research and Technology Corporation	04/25/21	2D 3D TSV
US10774085	105	105	HGNC:8031	Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds	ARRAY BIOPHARMA INC.	04/25/21	2D 3D TSV
US10774071	762	381		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774056	197	71	HGNC:4852 HGNC:6251 HGNC:4854 HGNC:4853	Substituted piperazines as selective HDAC1,2 inhibitors	REGENACY PHARMACEUTICALS, INC.	04/25/21	2D 3D TSV
US10774092	345	343	HGNC:12558	ULK1 inhibitors and methods using same	SALK INSTITUTE FOR BIOLOGICAL STUDIES; SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE; YALE UNIVERSITY	04/25/21	2D 3D TSV
US10759805	43	43	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp.	04/19/21	2D 3D TSV
US10759799	40	20	HGNC:4617 HGNC:3091	Indazole containing macrocycles and therapeutic uses thereof	Samumed, LLC	04/19/21	2D 3D TSV
US10759813	222	220	HGNC:7154	Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	04/19/21	2D 3D TSV
US10759812	26	15	HGNC:85 HGNC:84	Thienopyrimidine derivative and use thereof in medicine	Sunshine Lake Pharma Co., Ltd.	04/19/21	2D 3D TSV
US10759793	318	106		2-(pyrazolopyridin-3-yl)pyrimidine derivatives as JAK inhibitors	Almirall, S.A.	04/18/21	2D 3D TSV
US10759794	172	77	HGNC:6283 HGNC:6278	2-phenyl-3-(piperazinomethyl)imidazo[1,2-A]pyridine derivatives as blockers of task-1 and task-2 channels, for the treatment of sleep-related breathing disorders	BAYER PHARMA AKTIENGESELLSCHAFT	04/18/21	2D 3D TSV
US10759787	43	33		Benzofuran derivative, preparation method thereof and use thereof in medicine	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	04/18/21	2D 3D TSV
US10759796	139	138		CXCR4 inhibitors and uses thereof	X4 PHARMACEUTICALS, INC.	04/18/21	2D 3D TSV
US10759792	26	26		CaMKII inhibitors and uses thereof	The Johns Hopkins University	04/18/21	2D 3D TSV
US10759777	138	138	HGNC:8846	Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators	Synchronicity Pharma, Inc.	04/18/21	2D 3D TSV
US10758530	28	20	HGNC:10435 HGNC:10431 HGNC:10430 HGNC:10432	Carboxamide derivatives useful as rsk inhibitors	PHOENIX MOLECULAR DESIGNS	04/18/21	2D 3D TSV
US10759766	58	32	HGNC:6307	Certain chemical entities, compositions, and methods	NEUPHARMA, INC.	04/18/21	2D 3D TSV
US10759769	46	46	HGNC:12524	Glucosylceramide synthase inhibitors for the treatment of diseases	TBA	04/18/21	2D 3D TSV
US10759791	104	24	HGNC:7872	Mammalian and bacterial nitric oxide synthase inhibitors	Northwestern University	04/18/21	2D 3D TSV
US10759788	6	2	HGNC:6251 HGNC:6255	Pharmaceutical uses of pyridine carboxamide derivatives	JIANGSU HENGRUI MEDICINE CO., LTD.; SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.	04/18/21	2D 3D TSV
US10758542	530	232	HGNC:8031 HGNC:12440	Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharma Inc.	04/18/21	2D 3D TSV
US10758539	7	7	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	04/18/21	2D 3D TSV
US10745383	8	8		1,3,5-triazine derivative and method of using same	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.; Centaurus Biopharma Co., Ltd.	04/13/21	2D 3D TSV
US10744128	140	66	HGNC:4617 HGNC:3091	6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof	Samumed, LLC	04/13/21	2D 3D TSV
US10744125	24	6	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Adenosine A3 receptor modulators	Palobiofarma, S.L.	04/13/21	2D 3D TSV
US10745392	57	19	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	04/13/21	2D 3D TSV
US10745401	582	190	HGNC:3023 HGNC:5286	Condensed lactam derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	04/13/21	2D 3D TSV
US10745399	334	57	HGNC:8978 HGNC:795 HGNC:8975 HGNC:3942 HGNC:8977 HGNC:8976	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	04/13/21	2D 3D TSV
US10745388	16	16	HGNC:6863	Indazole compounds and uses thereof	Incyte Corporation	04/13/21	2D 3D TSV
US10745380	2	2	HGNC:10894	Pyridine derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	04/13/21	2D 3D TSV
US10745410	18	18		Substituted [5,6]cyclic-4(3H)-pyrimidinones as anticancer agents	ZENJI RESEARCH LABORATORIES	04/13/21	2D 3D TSV
US10745364	424	420		Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation; Merck Sharp & Dohme Corp.	04/13/21	2D 3D TSV
US10745420	101	96		Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	04/13/21	2D 3D TSV
US10744104	41	40	HGNC:7154	Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	04/12/21	2D 3D TSV
US10744117	5	5	HGNC:9236	PPARG modulators for the treatment of osteoporosis	The Scripps Research Institute; The University of Toledo	04/12/21	2D 3D TSV
US10752581	86	75	HGNC:429 HGNC:433	4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase	Eastern Virginia Medical School; The Regents of the University of California Santa; The United States of America Department of Health; Thomas Jefferson University	04/11/21	2D 3D TSV
US10752632	6	6	HGNC:7056	6-fluoro 2-methylbenzo[d]thiazol-5-yl compounds	Eli Lilly and Company	04/11/21	2D 3D TSV
US10752598	20	20		Aryldiazepine derivatives as RSV inhibitors	Enanta Pharmaceuticals, Inc.	04/11/21	2D 3D TSV
US10752616	136	46	HGNC:9864 HGNC:9866 HGNC:9865	Bicycloheteroaryl-heteroaryl-benzoic acid compounds as retinoic acid receptor beta (RARβ) agonists	King''s College London	04/11/21	2D 3D TSV
US10752604	35	20	HGNC:11037 HGNC:11036	C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same	Je II Pharmaceutical Co., Ltd.	04/11/21	2D 3D TSV
US10752613	21	15	HGNC:12805 HGNC:17989	Compounds and their use for reducing uric acid levels	Acquist LLC	04/11/21	2D 3D TSV
US10752588	28	27	HGNC:3023	Dopamine D2 receptor ligands	The Broad Institute, Inc.; Massachusetts Institute of Technology	04/11/21	2D 3D TSV
US10752623	196	62	HGNC:10593 HGNC:10585 HGNC:10596	Heteroaryl-substituted sulfonamide compounds and their use as sodium channel inhibitors	Xenon Pharmaceuticals Inc.	04/11/21	2D 3D TSV
US10752631	37	12	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Heterocyclic compounds as FGFR inhibitors	Guangzhou Innocare Pharma Tech Co., Ltd.	04/11/21	2D 3D TSV
US10752626	25	25		Iso-citrate dehydrogenase (IDH) inhibitor	SHANGHAI METON PHARMACEUTICAL CO., LTD	04/11/21	2D 3D TSV
US10752592	113	38	HGNC:8156	Morphan and morphinan analogues, and methods of use	ALKERMES PHARMA IRELAND LIMITED	04/11/21	2D 3D TSV
US10752596	153	152		Nitrogen-containing heteroaryl compound and pharmaceutical use thereof	JAPAN TOBACCO INC.	04/11/21	2D 3D TSV
US10751335	60	28	HGNC:8156	Signaling-biased mu opioid receptor agonists	THE SCRIPPS RESEARCH INSTITUTE	04/11/21	2D 3D TSV
US10752615	526	148	HGNC:1133 HGNC:6171 HGNC:11719 HGNC:12434	Spirocyclic containing compounds and pharmaceutical uses thereof	GB005, Inc.	04/11/21	2D 3D TSV
US10751339	55	14	HGNC:8979 HGNC:8978 HGNC:6251	Substituted aminopyrimidine compounds and methods of use	SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC	04/11/21	2D 3D TSV
US10738015	84	42	HGNC:8155 HGNC:8156	1,3-diaza-spiro-[3.4]-octane derivatives	GRÜNENTHAL GMBH	04/04/21	2D 3D TSV
US10738063	246	64		6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds	Pfizer Inc.	04/04/21	2D 3D TSV
US10738007	130	97	HGNC:10251 HGNC:10252	Amide compounds as kinase inhibitors, compositions and methods of treatment	Translation Drug Development, LLC	04/04/21	2D 3D TSV
USRE48150	34	33	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences, Inc.	04/04/21	2D 3D TSV
US10736881	141	96	HGNC:4852 HGNC:13315	Benzimidazole derivatives: preparation and pharmaceutical applications	MEI Pharma, Inc.	04/04/21	2D 3D TSV
US10738053	42	4	HGNC:1373 HGNC:10548	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	04/04/21	2D 3D TSV
US10738048	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10738074	43	29		Cyclic di-nucleotide compounds as STING agonists	Merck Sharp & Dohme Corp.	04/04/21	2D 3D TSV
US10738052	205	204	HGNC:7029	Imidazotriaines and imidazopyrimidines as kinase inhibitors	INCYTE HOLDINGS CORPORATION; INCYTE CORPORATION	04/04/21	2D 3D TSV
US10738026	17	11	HGNC:10597	Isoquinoline derivatives and use thereof	Purdue Pharma L.P.	04/04/21	2D 3D TSV
US10736890	75	37	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	04/04/21	2D 3D TSV
US10738056	517	508		Pyrazolopyrimidinone compounds and uses thereof	Aduro BioTech Inc.	04/04/21	2D 3D TSV
US10738009	160	158	HGNC:10582	Pyridone amides as modulators of sodium channels	VERTEX PHARMACEUTICALS INCORPORATED	04/04/21	2D 3D TSV
US10736974	64	35	HGNC:3788	Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy	THE JOHNS HOPKINS UNIVERSITY	04/04/21	2D 3D TSV
US10738057	246	118	HGNC:8978 HGNC:8977	Tertiary alcohols as PI3K-γ inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10736883	326	315	HGNC:339	Triazole furan compounds as agonists of the APJ receptor	AMGEN INC.	04/04/21	2D 3D TSV
US10723742	270	242	HGNC:29079	Biphenyl compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	03/30/21	2D 3D TSV
US10730902	10	5	HGNC:6561 HGNC:6563	1,1 ′-sulfanediyl-di-beta-D-galactopyranosides as inhibitors of galectins	GALECTO BIOTECH AB	03/28/21	2D 3D TSV
US10730889	403	380	HGNC:30092	Amido spirocyclic amide and sulfonamide derivatives	FORMA TM, LLC; Genentech, Inc.	03/28/21	2D 3D TSV
US10723734	237	230	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10722495	51	51	HGNC:6863	Cyanoindazole compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10722597	33	4	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Cyclodextrin-panobinostat adduct	MIDATECH LTD.	03/28/21	2D 3D TSV
US10722489	10	10	HGNC:8923	D-3-phosphoglycerate dehydrogenase allosteric inhibitor and use thereof	Peking University	03/28/21	2D 3D TSV
US10723705	206	204	HGNC:13315	Heterocyclic compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10723709	26	6	HGNC:2536 HGNC:2537 HGNC:2545	Protease inhibitors	MEDIVIR AB	03/28/21	2D 3D TSV
US10723723	220	173	HGNC:6255	Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10730882	34	34	HGNC:10436	2-aminoquinazoline derivatives as P70S6 kinase inhibitors	SENTINEL ONCOLOGY LIMITED	03/27/21	2D 3D TSV
US10730880	867	199	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as Janus kinase inhibitors	Array BioPharma Inc.; Celgene Corporation	03/27/21	2D 3D TSV
US10730877	3210	841	HGNC:15633 HGNC:15631 HGNC:15632	4-Azaindole compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730868	104	95	HGNC:3540	Bicyclic heteroaryl substituted compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730870	267	140	HGNC:12687	Compounds and methods for the enhanced degradation of targeted proteins	ARVINAS OPERATIONS, INC.; YALE UNIVERSITY	03/27/21	2D 3D TSV
US10730865	49	49		Compounds for modulating aquaporins	APOGLYX AB	03/27/21	2D 3D TSV
US10730860	3	2	HGNC:13575	Diaminopyrimidine benzenesulfone derivatives and uses thereof	Dana-Farber Cancer Institute, Inc.	03/27/21	2D 3D TSV
US10730881	28	28	HGNC:620	Fused pyrimidine derivatives	HOFFMANN-LA ROCHE, INC.	03/27/21	2D 3D TSV
US10730866	84	72	HGNC:10597	Indole derivatives and use thereof	Purdue Pharma L.P.	03/27/21	2D 3D TSV
US10730874	328	296	HGNC:6371	Inhibitors of plasma kallikrein and uses thereof	Shire Human Genetic Therapies, Inc.	03/27/21	2D 3D TSV
US10730875	135	31	HGNC:6190 HGNC:6192 HGNC:12440	Substituted imidazo[1,2-A]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof	JN Therapeutics	03/27/21	2D 3D TSV
US10729680	63	63		5-substituted 2-(morpholin-4-yl)-1,7-naphthyridines	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730832	130	130		Aliphatic prolinamide derivatives	ORION OPHTHALMOLOGY LLC	03/21/21	2D 3D TSV
US10729684	24	12	HGNC:10597	Alkynyl dihydroquinoline sulfonamide compounds	AMGEN INC.	03/21/21	2D 3D TSV
US10729695	29	29	HGNC:320	Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereof	The Research Foundation for the State University of New York; New York University	03/21/21	2D 3D TSV
US10730856	12	12	HGNC:9596	Benzimidazole derivatives as EP4 ligands	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730849	95	51		Benzo[b]thiophene compounds as STING agonists	Merck Sharp & Dohme Corp.	03/21/21	2D 3D TSV
US10730863	435	427	HGNC:7967	Bridged bicyclic compounds as farnesoid X receptor modulators	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10729710	17	6	HGNC:3023 HGNC:3020	Catecholamine prodrugs for use in the treatment of Parkinson's disease	H. Lundbeck A/S	03/21/21	2D 3D TSV
US10717746	178	86	HGNC:1780	Chemical compounds	ASTRAZENECA AB	03/21/21	2D 3D TSV
US10730853	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	03/21/21	2D 3D TSV
US10717737	116	115	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/21/21	2D 3D TSV
US10717733	462	116	HGNC:6834 HGNC:550 HGNC:6666	Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10717734	176	44	HGNC:6834 HGNC:550 HGNC:6666	Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10716791	42	17	HGNC:18367 HGNC:18368	Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof	University Health Network	03/21/21	2D 3D TSV
US10730826	181	68	HGNC:2531 HGNC:2538 HGNC:2527 HGNC:2536 HGNC:2547 HGNC:2537 HGNC:2545 HGNC:2535	Ketone inhibitors of lysine gingipain	CORTEXYME, INC.	03/21/21	2D 3D TSV
US10717708	62	31	HGNC:3827 HGNC:3826	Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10730850	106	106	HGNC:550	Pyridinylmethyl carbamimidoylcarbamate derivatives and their use as AOC3 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10717738	29	29	HGNC:3529	Pyrimidinone and its derivatives inhibiting factor XIa	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717742	148	137		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10730833	9	9	HGNC:348	Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them	Wisconsin Alumni Research Foundation	03/21/21	2D 3D TSV
US10730830	51	25	HGNC:3165 HGNC:14299	Tetrahydronaphthalene derivative	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717764	402	207		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	03/21/21	2D 3D TSV
US10729691	118	59	HGNC:11005	Treatment of infectious diseases with glucose uptake inhibitors	KADMON CORPORATION, LLC	03/21/21	2D 3D TSV
US10711036	87	87	HGNC:6819	MALT1 inhibitors and uses thereof	Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation	03/15/21	2D 3D TSV
US10711006	65	28	HGNC:4840 HGNC:3697 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:2444 HGNC:3765	Selective Bruton's tyrosine kinase inhibitor and use thereof	HANGZHOU HERTZ PHARMACEUTICAL CO., LTD.	03/15/21	2D 3D TSV
US10711007	49	49	HGNC:10894	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	03/15/21	2D 3D TSV
US10711020	881	783		Tricyclic sulfones as RORγ modulators	Bristol-Myers Squibb Company	03/15/21	2D 3D TSV
US10709688	40	16	HGNC:3559 HGNC:3557	Agent for treating synucleinopathy	Tohoku University; National University Corporation Okayama University	03/14/21	2D 3D TSV
US10710980	616	88		Aminopyridine derivatives and their use as selective ALK-2 inhibitors	Novartis AG	03/14/21	2D 3D TSV
US10709712	2614	1072	HGNC:9829	Biaryl amide compounds as kinase inhibitors	NOVARTIS AG	03/14/21	2D 3D TSV
US10709695	2	2		Compounds as rearranged during transfection (RET) inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED	03/14/21	2D 3D TSV
US10709718	28	28	HGNC:2843	Inhibitors of diacylglycerol O-acyltransferase 1 (DGAT-1) and uses thereof	Metabasis Therapeutics, Inc.	03/14/21	2D 3D TSV
US10710994	297	150	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10711004	455	275	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10710986	657	656		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	03/14/21	2D 3D TSV
US10710967	299	294	HGNC:9599	Pyrimidine derivative	ASKA PHARMACEUTICAL CO., LTD.	03/14/21	2D 3D TSV
US10710978	234	59	HGNC:11403 HGNC:11408 HGNC:18174 HGNC:11406	STK4 inhibitors for treatment of hematologic malignancies	DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE	03/14/21	2D 3D TSV
US10709719	42	10	HGNC:3167 HGNC:3165	Substituted bicyclic compounds	Bristol-Myers Squibb Company	03/14/21	2D 3D TSV
US10709709	212	203	HGNC:10894	Substituted carbonucleoside derivatives useful as anticancer agents	Pfizer Inc.	03/14/21	2D 3D TSV
US10676499	33	17	HGNC:3287	3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA	NOVARTIS AG	03/11/21	2D 3D TSV
US10676464	43	43		5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University Of The Commonwealth System of Higher Education	03/11/21	2D 3D TSV
US10676458	17	11	HGNC:4498	Antidiabetic bicyclic compounds	Merch Sharp & Dohne Corp. Rahway	03/11/21	2D 3D TSV
US10676467	113	58	HGNC:3169 HGNC:3167 HGNC:3165 HGNC:14299 HGNC:3170	Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof	Washington University	03/11/21	2D 3D TSV
US10676457	130	129	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/11/21	2D 3D TSV
US10676465	188	94	HGNC:4324	GLP-1 receptor agonists and uses thereof	Pfizer Inc.	03/11/21	2D 3D TSV
US10676479	360	118	HGNC:17101	Imidazolepyridine compounds and uses thereof	Novartis AG	03/11/21	2D 3D TSV
US10676470	36	34		Inhibitors of lysine gingipain	CORTEXYME, INC.	03/11/21	2D 3D TSV
US10676469	383	182	HGNC:8154 HGNC:8156	Kappa opioid receptor antagonists and products and methods related thereto	BLACKTHORN THERAPEUTICS, INC.; THE SCRIPPS RESEARCH INSTITUTE	03/11/21	2D 3D TSV
US10676485	106	53	HGNC:6943	Macrocyclic MCL-1 inhibitors and methods of use	AbbVie Inc.	03/11/21	2D 3D TSV
US10676460	56	3	HGNC:9077 HGNC:11283 HGNC:11584 HGNC:14552 HGNC:17967 HGNC:12434 HGNC:11724 HGNC:6735 HGNC:2451 HGNC:5465 HGNC:4617 HGNC:2459 HGNC:6112 HGNC:2457 HGNC:3767 HGNC:6190 HGNC:6192 HGNC:6193 HGNC:6171 HGNC:11390 HGNC:12440 HGNC:1079 HGNC:1771 HGNC:1133 HGNC:6860 HGNC:7972 HGNC:6524 HGNC:1775	Quinazolines as potassium ion channel inhibitors	Bristol-Myers Squibb Company	03/11/21	2D 3D TSV
US10676476	30	14	HGNC:3430 HGNC:5253	Small-molecule HSP90 inhibitors	Sloan-Kettering Institute for Cancer Research	03/11/21	2D 3D TSV
US10676446	190	190	HGNC:3357	Bicyclic quinazolinone derivatives	Hoffmann-La Roche Inc.	03/10/21	2D 3D TSV
US10676434	200	178	HGNC:1133	Carbazole derivatives	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675286	612	109	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals, Inc.	03/10/21	2D 3D TSV
US10676433	355	196	HGNC:5992 HGNC:8537	Indole derivatives and their use in neurodegenerative diseases	Merck Patent GmbH	03/10/21	2D 3D TSV
US10676438	16	10	HGNC:6251	KCNQ2-5 channel activator	Ono Pharmaceutical Co., Ltd.	03/10/21	2D 3D TSV
US10676431	270	127	HGNC:3827 HGNC:3826	Phenylpyrrolidinone formyl peptide 2 receptor agonists	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675268	284	169	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin receptor subtype 4 (SSTR4) agonists	Centrexion Therapeutics Corporation	03/10/21	2D 3D TSV
US10675284	37	37	HGNC:6190 HGNC:8977	Treatment of B-cell malignancies by a combination JAK and PI3K inhibitors	Incyte Corporation	03/10/21	2D 3D TSV
US10703751	36	7	HGNC:6192 HGNC:6193	Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof	Leo Pharma A/S	03/08/21	2D 3D TSV
US10703741	26	16	HGNC:18368	Covalent inhibitors of PAD4	Padlock Therapeutics, Inc.	03/08/21	2D 3D TSV
US10702504	21	21	HGNC:11812	Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use	DANA-FARBER CANCER INSTITUTE, INC.	03/08/21	2D 3D TSV
US10703733	457	445		MCL-1 inhibitors	Gilead Sciences, Inc.	03/08/21	2D 3D TSV
US10702498	27	15	HGNC:8154 HGNC:8156	MU opioid receptor modulators	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NÜRNBERG; THE BOARD OF TRUSTEES OFTHE LELAND STANFORD JUNIOR UNIVERSITY; THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	03/08/21	2D 3D TSV
US10703749	843	289	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	03/08/21	2D 3D TSV
US10708263	5	1		Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	03/08/21	2D 3D TSV
US10703740	14	14	HGNC:13575	Substituted benzimidazoles, their preparation and their use as pharmaceuticals	Neomed Institute	03/08/21	2D 3D TSV
US10703755	351	337	HGNC:15631	Substituted purine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	03/08/21	2D 3D TSV
US10696692	374	308	HGNC:30092	Amido-benzyl sulfone and sulfoxide derivates	TBA	03/02/21	2D 3D TSV
US10696672	157	152	HGNC:6161	Amino acid compounds and methods of use	Pliant Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696682	44	44	HGNC:1771	CDK inhibitors	G1 Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696661	70	69	HGNC:11305	Compounds	Exonate Limited	03/02/21	2D 3D TSV
US10696638	48	43	HGNC:10251 HGNC:10252	Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same	INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE	03/02/21	2D 3D TSV
US10695334	98	57	HGNC:6371 HGNC:11830	Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	03/02/21	2D 3D TSV
US10696678	154	64	HGNC:1722	Kinase inhibitor, and preparing method and pharmaceutical use thereof	GAN & LEE PHARMACEUTICALS	03/02/21	2D 3D TSV
US10696665	61	23	HGNC:5382	Mutant IDH1 inhibitors	Eli Lilly and Company	03/02/21	2D 3D TSV
US10695337	794	388		Piperidin-4-yl azetidine derivatives as JAK1 inhibitors	Incyte Holdings Corporation; Incyte Corporation	03/02/21	2D 3D TSV
US10695347	84	40	HGNC:427	Pyrimidine derivative and use thereof	HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC.	03/02/21	2D 3D TSV
US10696660	91	36	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation, LLC	03/02/21	2D 3D TSV
US10696689	23	23	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10696655	125	125	HGNC:2348	Therapeutic compounds and uses thereof	GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10689373	308	149	HGNC:4849 HGNC:4848	1,2-substituted cyclopentanes as orexin receptor antagonists	TAKEDA PHARMACEUTICAL COMPANY LIMITED	02/22/21	2D 3D TSV
US10689345	273	269		1-cyano-pyrrolidine compounds as USP30 inhibitors	Mission Therapeutics Limited	02/22/21	2D 3D TSV
US10689401	50	25	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689705	212	71	HGNC:3690 HGNC:3689 HGNC:3688	FGFR3 fusion gene and pharmaceutical drug targeting same	Chugai Seiyaku Kabushiki Kaisha	02/22/21	2D 3D TSV
US10689346	302	246	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10688100	52	13	HGNC:10261	Macrocylic compounds as ROS1 kinase inhibitors	Array BioPharma Inc.	02/22/21	2D 3D TSV
US10688093	708	647	HGNC:4037	Methods, compositions, and uses of novel Fyn kinase inhibitors	TBA	02/22/21	2D 3D TSV
US10689357	43	43	HGNC:736	N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof	NORTHEASTERN UNIVERSITY	02/22/21	2D 3D TSV
US10689398	91	89	HGNC:8157	OXA-Diazaspiro compounds having activity against pain	ESTEVE PHARMACEUTICALS, S.A.	02/22/21	2D 3D TSV
USRE48059	122	64		Piperazine-substituted benzothiophenes for treatment of mental disorders	Otsuka Pharmaceutical Co., Ltd.	02/22/21	2D 3D TSV
US10689327	30	15	HGNC:4595 HGNC:4594	Prodrug amino acid derivative	TAISHO PHARMACEUTICAL CO., LTD.	02/22/21	2D 3D TSV
US10689339	69	69	HGNC:2545	Pyrrolidine derivatives	Hoffmann-La Roche Inc.	02/22/21	2D 3D TSV
US10689362	508	124	HGNC:8804 HGNC:6342 HGNC:3765	Quinoxaline compounds as type III receptor tyrosine kinase inhibitors	Development Center for Biotechnology	02/22/21	2D 3D TSV
US10689399	23	23	HGNC:9213	Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections	Gilead Sciences, Inc.	02/22/21	2D 3D TSV
US10689369	149	127		Substituted indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689376	39	39	HGNC:3356	Substituted-3H-imidazo [4,5-c] pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics	Stingray Therapeutics, Inc.; The University of Utah	02/22/21	2D 3D TSV
US10689414	404	206		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10689367	327	233	HGNC:339	Triazole pyridyl compounds as agonists of the APJ receptor	AMGEN INC.	02/22/21	2D 3D TSV
US10689390	18	18	HGNC:13575	Tricyclic fused derivatives of 1-(cyclo)alkyl pyridin-2-one useful for the treatment of cancer	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10689395	14	14	HGNC:13575	Tricyclic fused pyridin-2-one derivatives and their use as BRD4 inhibitors	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10669240	500	242	HGNC:3091	5-substituted indazole-3-carboxamides and preparation and use thereof	Samumed, LLC	02/21/21	2D 3D TSV
US10669246	153	115	HGNC:8803 HGNC:76 HGNC:6342	Benzothiazol compounds and methods using the same for treating neurodegenerative disorders	1ST Biotherapeutics, Inc.	02/21/21	2D 3D TSV
US10669268	343	306	HGNC:10548	Bicyclic derivatives	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669289	209	104	HGNC:9542 HGNC:9545	Boronic acid derivatives	MERCK PATENT GMBH	02/21/21	2D 3D TSV
US10669245	37	37	HGNC:2528	Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides dipeptidyl peptidase 1 inhibitors	ASTRAZENECA AB	02/21/21	2D 3D TSV
US10669285	43	43	HGNC:10548	Condensed [1,4] diazepine compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669276	48	48		Fused pyrimidine derivatives	HOFFMANN-LA ROCHE INC.	02/21/21	2D 3D TSV
US10669271	94	30	HGNC:7794 HGNC:9644	Heterocyclic compounds as immunomodulators	Incyte Corporation	02/21/21	2D 3D TSV
US10669279	372	104	HGNC:8780 HGNC:8781 HGNC:8783	Imidazopyridazine compounds	Pfizer Inc.	02/21/21	2D 3D TSV
US10669243	10	10		Isoxazole carboxamides as irreversible SMYD inhibitors	EPIZYME, INC.	02/21/21	2D 3D TSV
US10669296	8	4		LXR agonists and uses thereof	Rgenix, Inc.	02/21/21	2D 3D TSV
US10669265	142	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	ALLERGAN, INC.	02/21/21	2D 3D TSV
US10669267	65	39	HGNC:8537	Substituted N-[2-(4-phenoxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide and N-[2-(4-benzyloxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide derivatives P2X7 receptor antagonists	Axxam S.P.A.	02/21/21	2D 3D TSV
US10669273	42	36	HGNC:6059	Use of aza-tryptanthrin derivatives as inhibitors of IDO1 and/or TDO	Peking University	02/21/21	2D 3D TSV
US10683294	67	67	HGNC:1338	5-5 fused rings as C5a inhibitors	ChemoCentryx, Inc.	02/16/21	2D 3D TSV
US10683295	59	29	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-A]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof	Ogeda SA	02/16/21	2D 3D TSV
US10683291	3	3	HGNC:3165	Heterocyclic compounds for the treatment of disease	OPPILAN PHARMA LTD.	02/16/21	2D 3D TSV
US10683290	84	80		Tricyclic compounds as anticancer agents	Bristol-Myers Squibb Company	02/16/21	2D 3D TSV
US10683309	84	42	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V.	02/16/21	2D 3D TSV
US10668071	105	100		(Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use	BAYER PHARMA AKTIENGESELLSCHAFT	02/15/21	2D 3D TSV
US10667515	17	17		(S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using	Iowa State University Research Foundation, Inc.	02/15/21	2D 3D TSV
US10683279	71	68	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10683289	23	23	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10682352	117	100	HGNC:5382	Compound having mutant IDH inhibitory activity, preparation method and use thereof	SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	02/15/21	2D 3D TSV
US10669227	24	9	HGNC:7175 HGNC:7176 HGNC:7166 HGNC:7159	Curcumin analogues as zinc chelators and their uses	THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK	02/15/21	2D 3D TSV
US10669234	193	147	HGNC:12513	Cyanopyrrolidines as dub inhibitors for the treatment of cancer	MISSION THERAPEUTICS LIMITED	02/15/21	2D 3D TSV
US10668167	176	62	HGNC:7978 HGNC:644 HGNC:3467 HGNC:8910	Glucocorticoid receptor agonist and immunoconjugates thereof	AbbVie Inc.	02/15/21	2D 3D TSV
US10683287	96	45	HGNC:934 HGNC:933	Heterocyclic derivatives and their use in the treatment of neurological disorders	Novartis AG	02/15/21	2D 3D TSV
US10669235	336	55	HGNC:8803 HGNC:3763 HGNC:6307 HGNC:8804 HGNC:3690 HGNC:3688	Indole derivatives and their use as protein kinase inhibitors	RESPIVERT LIMITED	02/15/21	2D 3D TSV
US10668051	56	56	HGNC:25896	Modulators of calcium release-activated calcium channel	RHIZEN PHARMACEUTICALS SA	02/15/21	2D 3D TSV
US10668033	4	4	HGNC:9602	Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto	ARENA PHARMACEUTICALS, INC.	02/15/21	2D 3D TSV
US10668067	135	135	HGNC:10597	Pyridine sulfonamides	AMGEN INC.	02/15/21	2D 3D TSV
US10668094	92	21		Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure	Yeda Research and Development Co. Ltd.	02/15/21	2D 3D TSV
US10669239	74	68	HGNC:8031	Tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	02/15/21	2D 3D TSV
US10660877	2542	841	HGNC:15633 HGNC:15631 HGNC:15632	Pyridyl substituted indole compounds	Bristol-Myers Squibb Company	02/08/21	2D 3D TSV
US10662159	204	60	HGNC:3553 HGNC:17038 HGNC:21398	ABHD6 and dual ABHD6/MGL inhibitors and their uses	MAKSCIENTIFIC, LLC	02/07/21	2D 3D TSV
US10660876	90	89	HGNC:2771	Amino compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	02/07/21	2D 3D TSV
US10662184	150	83	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	02/07/21	2D 3D TSV
US10660898	27	27	HGNC:8972	Benzimidazole derivatives as PI3 kinase inhibitors	GLAXOSMITHKLINE LLC	02/07/21	2D 3D TSV
US10662187	134	124	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	Zibo Biopolar Changsheng Pharmaceutical Co. Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	02/07/21	2D 3D TSV
US10662156	94	90	HGNC:6819	Guanidine derivative and medical use thereof	Toray Industries, Inc.	02/07/21	2D 3D TSV
US10662189	84	78	HGNC:8781	PDE4 inhibitor	SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.	02/07/21	2D 3D TSV
US10662186	650	137	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:1774 HGNC:1773	Substituted pyrimidines as cyclin-dependent kinase inhibitors	SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.	02/07/21	2D 3D TSV
US10654833	96	90	HGNC:6857	ASK1 isoindolin-1-one inhibitors and methods of use thereof	Hepatikos Therapeutics, LLC	02/01/21	2D 3D TSV
US10654857	68	7	HGNC:10555	Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffman-La Roche Inc.	02/01/21	2D 3D TSV
US10654835	207	69		Compounds and methods for inhibiting JAK	Dizal (Jiangsu) Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654856	20	17	HGNC:15631 HGNC:15632	Method for preparing pyrrolo[3,2-D]pyrimidine compound, and intermediates thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.	02/01/21	2D 3D TSV
US10654855	73	73	HGNC:391	Protein kinase B inhibitors	AstraZeneca AB	02/01/21	2D 3D TSV
US10654836	40	10	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine derivative, method for preparing same and use thereof in medicine	Zhejiang Hisun Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654866	44	21	HGNC:3467	Selective estrogen receptor degraders	Eli Lilly and Company	02/01/21	2D 3D TSV
US10654853	147	145		Spiro-condensed pyrrolidine derivatives as deubiquitylating enzymes (DUB) inhibitors	MISSION THERAPEUTICS LIMITED	02/01/21	2D 3D TSV
US10654860	35	31	HGNC:10252	Tricyclic rho kinase inhibitors	Bristol-Myers Squibb Company	02/01/21	2D 3D TSV
US10653688	302	143	HGNC:4617 HGNC:3091	6-(6-membered heteroaryl and aryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	01/31/21	2D 3D TSV
US10654831	85	14	HGNC:1780 HGNC:1771 HGNC:1774 HGNC:1773 HGNC:1775	Antiproliferative pyrimidine-based compounds	G1 Therapeutics, Inc.	01/31/21	2D 3D TSV
US10654814	240	127	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853	Bicyclic hydroxamic acids useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	01/31/21	2D 3D TSV
US10653701	103	52	HGNC:6307 HGNC:1133 HGNC:6193 HGNC:3689 HGNC:3236 HGNC:3688	Substituted quinazolines for inhibiting kinase activity	NEUPHARMA, INC.	01/31/21	2D 3D TSV
US10647665	39	33		Biaryl urea derivative or salt thereof and preparation process and use for the same	Fudan University	01/25/21	2D 3D TSV
US10647719	107	5	HGNC:10555 HGNC:1373	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	01/25/21	2D 3D TSV
US10647706	40	14	HGNC:6026 HGNC:6027	Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies	GALDERMA RESEARCH & DEVELOPMENT	01/25/21	2D 3D TSV
US10647694	45	40	HGNC:427	Diphenylaminopyrimidine and triazine compound, and pharmaceutical composition and use thereof	ARROMAX PHARMATECH CO., LTD.	01/25/21	2D 3D TSV
US10647700	14	14		EZH2 inhibitor and use thereof	TARAPEUTICS SCIENCE INC.	01/25/21	2D 3D TSV
US10646575	3	3	HGNC:2717	Heterocyclic degronimers for target protein degradation	C4 Therapeutics, Inc.	01/25/21	2D 3D TSV
US10646492	366	342	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Corporation; Incyte Holdings Corporation	01/25/21	2D 3D TSV
US10647720	614	333	HGNC:6192 HGNC:11491	Pyrimido-pyridazinone compounds and methods of use thereof	Asan BioSciences, LLC	01/25/21	2D 3D TSV
US10647727	66	47		Substituted pyrazolo/imidazolo bicyclic compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp.	01/25/21	2D 3D TSV
US10647686	82	50	HGNC:11396 HGNC:11395	Substituted pyrimidines for preventing or treating cancer and inflammatory diseases	KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY	01/25/21	2D 3D TSV
US10647713	620	601		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	01/25/21	2D 3D TSV
US10647708	46	46	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD	01/25/21	2D 3D TSV
US10639286	194	172		Alkoxy compounds for disease treatment	ACUCELA INC.	01/18/21	2D 3D TSV
US10640498	69	68		Compounds	MISSION THERAPEUTICS LIMITED	01/18/21	2D 3D TSV
US10640533	114	19	HGNC:2524 HGNC:24059 HGNC:9537	Epoxyketone compounds for enzyme inhibition	CENTRAX INTERNATIONAL, INC.	01/18/21	2D 3D TSV
US10640486	86	85	HGNC:1133	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	01/18/21	2D 3D TSV
US10640495	646	615	HGNC:8031	Heterocycle derivatives having TrkA inhibitory activity	Shionogi & Co., Ltd.	01/18/21	2D 3D TSV
US10640503	158	158	HGNC:29079	Imidazopyridines and imidazopyrazines as LSD1 inhibitors	Incyte Corporation	01/18/21	2D 3D TSV
US10639284	329	312	HGNC:17635	Immunomodulator compounds	ChemoCentryx, Inc.	01/18/21	2D 3D TSV
US10640491	20	20	HGNC:1133	Inhibitors of bruton's tyrosine kinase	HOFFMANN-LA ROCHE INC.	01/18/21	2D 3D TSV
US10640534	402	205		Therapeutically active compositions and their methods of use	Agios Pharmaceuticals, Inc.	01/18/21	2D 3D TSV
US10633384	113	113	HGNC:10555	Diazaspirocycloalkane and azaspirocycloalkane	Hoffmann-La Roche Inc.	01/12/21	2D 3D TSV
US10632126	676	168	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	01/10/21	2D 3D TSV
US10633379	264	130		Bromodomain inhibitors	AbbVie Inc.	01/10/21	2D 3D TSV
US10633389	1029	1023	HGNC:23393	CARM1 inhibitors and uses thereof	Epizyme, Inc.	01/10/21	2D 3D TSV
US10632122	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	01/10/21	2D 3D TSV
US10633345	302	248	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	01/10/21	2D 3D TSV
US10632171	152	130	HGNC:6932 HGNC:4479	Melanocortin receptor-specific peptides	Palatin Technologies, Inc.	01/10/21	2D 3D TSV
US10633348	39	16	HGNC:4840 HGNC:1133 HGNC:4195 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	01/10/21	2D 3D TSV
US10633375	111	107	HGNC:3529	Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof	Jinagsu Hengrui Medicine Co., Ltd; Shanghai Hengrui Pharmaceutical Co., Ltd.	01/10/21	2D 3D TSV
US10633388	19	14	HGNC:4421	Pyrazolopyrimidone derivatives and methods of use thereof	Shanghai Hengrui Pharmaceutical Co., ltd.; Jiangsu Hangrui Medicine Co., Ltd.	01/10/21	2D 3D TSV
US10633373	123	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	Allergan, Inc.	01/10/21	2D 3D TSV
US10604514	334	150	HGNC:4617 HGNC:3091	6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	12/21/20	2D 3D TSV
US10604534	38	19	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	12/21/20	2D 3D TSV
US10604535	251	240		Compounds, compositions and methods	Denali Therapeutics Inc.	12/21/20	2D 3D TSV
US10604531	11	11	HGNC:3527	Enhancer of zeste homolog 2 inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED	12/21/20	2D 3D TSV
US10604536	59	54	HGNC:8772	Substituted cyclopropanes as PDE-10 inhibitors	Sunovion Pharamaceuticals Inc.	12/21/20	2D 3D TSV
US10604508	11	11	HGNC:1133	2,3-dihydro-isoindole-1-one derivative as BTK kinase suppressant, and pharmaceutical composition including same	CrystalGenomics, Inc.	12/20/20	2D 3D TSV
US10603310	14	12	HGNC:933	2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618929	21	20	HGNC:15631	3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10618900	52	27	HGNC:4597 HGNC:4593	5-aromatic alkynyl substituted benzamide compound and preparation method, pharmaceutical composition, and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/20/20	2D 3D TSV
US10618914	79	43	HGNC:11364 HGNC:11362	6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-B][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity	University of Pittsburgh—Of the Commonwealth System of Higher Education	12/20/20	2D 3D TSV
US10603330	131	65	HGNC:663 HGNC:664	Arginase inhibitors as therapeutics	Mars, Incorporated	12/20/20	2D 3D TSV
US10618886	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	12/20/20	2D 3D TSV
US10604489	172	171	HGNC:8156	Compounds for the treatment of pain	Alkermes, Inc.	12/20/20	2D 3D TSV
US10603320	9	3	HGNC:10258	Compounds useful for inhibiting ROR-gamma-t	Eli Lilly and Company	12/20/20	2D 3D TSV
US10618884	16	1	HGNC:427	Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds	Suzhou Zelgen Biopharmaceuticals Co., Ltd.	12/20/20	2D 3D TSV
US10618912	55	18	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:427 HGNC:10261 HGNC:11397	Diaryl macrocycles as modulators of protein kinases	Turning Point Therapeutics, Inc.	12/20/20	2D 3D TSV
US10618903	287	262	HGNC:17967	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618916	68	68		Heterocyclic compounds as immunomodulators	Incyte Corporation	12/20/20	2D 3D TSV
US10604504	262	222	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618913	114	37	HGNC:8775 HGNC:8774 HGNC:8776	Macrocycles as PDE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618897	168	161	HGNC:2730	Spiroindolinones as DDR1 inhibitors	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10604502	112	111	HGNC:29079	Substituted 5-cyanoindole compounds and uses thereof	Novartis AG	12/20/20	2D 3D TSV
US10618902	256	249	HGNC:3691	Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases	Celgene CAR LLC; Sanofi	12/20/20	2D 3D TSV
US10618910	58	29		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	12/20/20	2D 3D TSV
US10597383	35	35		Bicyclic proline compounds	Genentech, Inc.	12/14/20	2D 3D TSV
US10597387	19	8	HGNC:4840 HGNC:1133 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	12/14/20	2D 3D TSV
US10597399	40	39	HGNC:270	Substituted triazolopiperazine PARP inhibitor, preparation method therefor and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/14/20	2D 3D TSV
US10597382	16	15	HGNC:6857	Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	12/14/20	2D 3D TSV
US10596172	747	259	HGNC:1079 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:3236	2,4-disubstituted pyrimidines useful as kinase inhibitors	Celgene CAR LLC	12/13/20	2D 3D TSV
US10597366	413	325	HGNC:12680 HGNC:3374	Aryl ethers and uses thereof	Peloton Therapeutics, Inc.	12/13/20	2D 3D TSV
US10596184	158	76	HGNC:8978 HGNC:8977	Aza-heteroaryl compounds as PI3K-gamma inhibitors	Incyte Corporation	12/13/20	2D 3D TSV
US10617673	8	8		Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes	Jenrin Discovery, LLC	12/13/20	2D 3D TSV
US10617706	43	42	HGNC:17768	Compounds for cancer chemotherapeutic sensitization	REGENTS OF THE UNIVERSITY OF MINNESOTA; THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES	12/13/20	2D 3D TSV
US10597367	724	191		Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	12/13/20	2D 3D TSV
US10610125	24	5	HGNC:5382 HGNC:6541 HGNC:6535	Methods and compositions for cell-proliferation-related disorders	Agios Pharmaceuticals, Inc.	12/13/20	2D 3D TSV
US10617692	4	4	HGNC:6192	Pyrrolopyrimidine comprising cyclopentyl substituent	CENTAURUS BIOPHARMA CO.; CHIA TAI TIANQING PHARMACEUTICAL GROUP CO.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	12/13/20	2D 3D TSV
US10597377	268	258	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	12/13/20	2D 3D TSV
US10617676	596	594	HGNC:4586	Substituted 1H-imidazo[4,5-b]pyridin-2(3H)-ones and their use as GluN2B receptor modulators	JANSSEN PHARMACEUTICA NV	12/13/20	2D 3D TSV
US10617680	423	397	HGNC:2348	Therapeutic compounds	CELGENE QUANTICEL RESEARCH, INC.	12/13/20	2D 3D TSV
US10617654	78	26	HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The USA, as represented by the Secretary, Department of Health and Human Services; SRI International	12/13/20	2D 3D TSV
US10590106	12	6	HGNC:6307	Certain chemical entities, compositions, and methods	NeuPharma, Inc.	12/08/20	2D 3D TSV
US10590105	56	56		1,3-dihydroxy-phenyl derivatives useful as immunomodulators	Bristol-Meyers Squibb Company	12/07/20	2D 3D TSV
US10611727	18	18		1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives	UNIVERSITAT DE BARCELONA; FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA; IPROTEOS S.L.	12/07/20	2D 3D TSV
US10611730	212	212	HGNC:13628	Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	12/07/20	2D 3D TSV
US10610539	14	14		Cardiac glycoside analogs and their use in methods for inhibition of viral infection	The John Hopkins University	12/07/20	2D 3D TSV
US10590130	121	63	HGNC:6251	Chemical compounds	AstraZeneca AB	12/07/20	2D 3D TSV
US10590114	215	161	HGNC:18618	Compounds, compositions, and methods	Denali Therapautics Inc.	12/07/20	2D 3D TSV
US10611770	26	26	HGNC:427	Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	12/07/20	2D 3D TSV
US10590075	29	29		Cyanopyrrolidine derivatives as inhibitors for DUBs	MISSION THERAPEUTICS LIMITED	12/07/20	2D 3D TSV
US10611751	15	15	HGNC:3020	Dopamine D1 receptor positive allosteric modulators	Eli Lilly and Company	12/07/20	2D 3D TSV
US10590109	85	24		Heterocyclic compounds used as FGFR inhibitors	Nanjing InnoCare Pharma Tech Co., Ltd.	12/07/20	2D 3D TSV
US10611763	116	114	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research, Inc.	12/07/20	2D 3D TSV
US10611777	156	69	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Imidazopyridazine compounds and their use	HUTCHISON MEDIPHARMA LIMITED	12/07/20	2D 3D TSV
US10611728	246	97	HGNC:6251 HGNC:8157	Isoindoline compositions and methods for treating neurodegenerative disease	COGNITION THERAPEUTICS, INC.	12/07/20	2D 3D TSV
US10590139	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc.	12/07/20	2D 3D TSV
US10611766	279	95	HGNC:1133 HGNC:3236	Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer	Loxo Oncology Inc.	12/07/20	2D 3D TSV
US10590132	289	159	HGNC:6251	Selective estrogen receptor down-regulators	AstraZeneca AB	12/07/20	2D 3D TSV
US10590077	7	7	HGNC:18083	TRPV4 antagonists	GlaxoSmithKline Intellectual Property Development Limited	12/07/20	2D 3D TSV
US10590140	785	438	HGNC:11048	Tetrahydropyrimidodiazepine and dihydropyridodiazepine compounds for treating pain and pain related conditions	ESTEVE PHARMACEUTICALS, S.A.	12/07/20	2D 3D TSV
US10570125	40	16	HGNC:2160 HGNC:2159	(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles	Centrexion Therapeutics Corporation	11/30/20	2D 3D TSV
US10570116	153	53	HGNC:270 HGNC:11941 HGNC:15677	1,4-dicarbonyl-piperidyl derivatives	Merck Patent GmbH	11/30/20	2D 3D TSV
US10568884	22	22		Compounds and compositions as protein kinase inhibitors	Array BioPharma Inc.	11/30/20	2D 3D TSV
US10570167	249	149	HGNC:8021	Ectonucleotidase inhibitors and methods of use thereof	Calithera Biosciences, Inc.	11/30/20	2D 3D TSV
US10570155	21	8	HGNC:9829 HGNC:1097	Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same	KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY	11/30/20	2D 3D TSV
US10570118	43	40	HGNC:1133	Isoquinolones as BTK inhibitors	Boehringer Ingelheim International GmbH	11/30/20	2D 3D TSV
US10570123	100	51	HGNC:10251 HGNC:10252	Pharmacokinetically improved compounds	SURFACE LOGIX, LLC	11/30/20	2D 3D TSV
US10570140	42	42	HGNC:29652	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	11/30/20	2D 3D TSV
US10570077	7	7	HGNC:3467	Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform	Marquette University; Concordia University Inc.	11/30/20	2D 3D TSV
US10570121	412	114	HGNC:3527	Substituted dihydroisoquinolinone compounds	Pfizer Inc.	11/30/20	2D 3D TSV
US10570156	42	42	HGNC:8772	Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors	SUNOVION PHARMACEUTICALS INC.	11/30/20	2D 3D TSV
US10570141	14	7	HGNC:1777 HGNC:1773	Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	11/30/20	2D 3D TSV
US10568876	141	138	HGNC:16940	Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharp & Dohme Corp.	11/30/20	2D 3D TSV
US10568888	26	13	HGNC:8781 HGNC:8783	Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	11/30/20	2D 3D TSV
US10584127	26	11	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	11/29/20	2D 3D TSV
US10584111	25	22	HGNC:4597	4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators	Heptares Therapeutics Limited	11/29/20	2D 3D TSV
US10577368	81	61	HGNC:268 HGNC:262 HGNC:263	A3 adenosine receptor agonists	The United States of America, as represented by the Secretary, Department of Health and Human Services; Saint Louis University	11/29/20	2D 3D TSV
US10584120	58	58	HGNC:9753	Benzimidazole compounds and use thereof for treating Alzheimer's Disease or Huntington's Disease	National Health Research Institutes; Academia Sinica	11/29/20	2D 3D TSV
US10577374	360	356	HGNC:1133	Bruton's tyrosine kinase inhibitors	Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.	11/29/20	2D 3D TSV
US10584104	18	18	HGNC:17989	Carboxylic acid URAT1 inhibitor containing diarylmethane structure, preparation method and use thereof	TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.	11/29/20	2D 3D TSV
US10584121	10	10		Heteroaryl substituted benzoic acids as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	11/29/20	2D 3D TSV
US10584116	51	51	HGNC:497	Heterocyclic sulfonamide derivative and medicine containing same	EA Pharma Co., Ltd.	11/29/20	2D 3D TSV
US10568874	8	8	HGNC:17635	Indane-amines as PD-L1 antagonists	ChemoCentryx, Inc.	11/29/20	2D 3D TSV
US10583140	12	12		Ingenol analogs, pharmaceutical compositions and methods of use thereof	GlaxoSmithKline Intellectual Property Development Limited	11/29/20	2D 3D TSV
US10584114	82	41	HGNC:9967	Inhibitors of RET	BLUEPRINT MEDICINES CORPORATION	11/29/20	2D 3D TSV
US10577383	78	37	HGNC:7218	Macrocyclic inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	11/29/20	2D 3D TSV
US10584098	12	12		Quinolone-3-diarylethers	Oregon Health & Science University	11/29/20	2D 3D TSV
US10584132	20	12	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	11/29/20	2D 3D TSV
US10584103	224	211	HGNC:8039	Small molecule agonists of neurotensin receptor 1	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	11/29/20	2D 3D TSV
US10584135	348	174	HGNC:3023 HGNC:3024	Substituted 3,6-diazabicyclo[3.2.0]heptanes	INDIVIOR UK LIMITED	11/29/20	2D 3D TSV
US10577373	1366	1143		TYK2 inhibitors and uses thereof	Nimbus Lakshimi, Inc.	11/29/20	2D 3D TSV
US10583137	116	56	HGNC:1165 HGNC:28923	Triazole DAGLα inhibitors	THE SCRIPPS RESEARCH INSTITUTE; LEIDEN UNIVERSITY	11/29/20	2D 3D TSV
US10584134	79	69	HGNC:17961	Use of physiological cooling active ingredients, and agents containing such active ingredients	SYMRISE AG; BASF SE	11/29/20	2D 3D TSV
US10561662	73	73	HGNC:19995	4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562893	49	22	HGNC:6171 HGNC:11719 HGNC:12434	Benzimidazoles derivatives as Tec kinases family inhibitors	GB005, INC.	11/22/20	2D 3D TSV
US10562890	16	15	HGNC:10471	Cancer therapeutics	UNIVERSITY OF VIRGINIA PATENT FOUNDATION	11/22/20	2D 3D TSV
US10562861	41	14	HGNC:6251 HGNC:15631 HGNC:15632	Carboxylic acid compounds	Sumitomo Dainippon Pharma Co., Ltd.	11/22/20	2D 3D TSV
US10562853	189	63	HGNC:3023 HGNC:5286 HGNC:277	Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-HT1A receptors	NEUROLIXIS; UNIVERSITE JAGELLONE	11/22/20	2D 3D TSV
US10562888	6	1	HGNC:3682 HGNC:3690 HGNC:3689 HGNC:3688	Crystalline FGFR4 inhibitor compound and uses thereof	Eisai R&D Management Co., LTD.	11/22/20	2D 3D TSV
US10562878	1149	222	HGNC:11050 HGNC:11049	Cycloalkylamines as monoamine reuptake inhibitors	SUNOVION PHARAMCEUTICALS INC.	11/22/20	2D 3D TSV
US10562844	14	14		HYPDH inhibitors and methods of use for the treatment of kidney stones	Wake Forest University Health Sciences; UAB Research Foundation	11/22/20	2D 3D TSV
US10562850	103	100	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562902	175	164	HGNC:17967	IRAK4 inhibitor and use thereof	Beijing Hanmi Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562900	131	57	HGNC:6307 HGNC:3690 HGNC:3689 HGNC:3688	Indazole compounds as FGFR kinase inhibitor, preparation and use thereof	Shanghai Haihe Pharmaceutical Co., Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	11/22/20	2D 3D TSV
US10562910	9	9	HGNC:7967	Nitrogen-containing tricyclic compounds and uses thereof in medicine	NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED	11/22/20	2D 3D TSV
US10561656	9	5	HGNC:8775 HGNC:8774	Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/22/20	2D 3D TSV
US10562882	43	41		Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562854	32	16	HGNC:1232 HGNC:12680	Prolyl hydroxylase inhibitors	AERPIO THERAPEUTICS, INC.	11/22/20	2D 3D TSV
US10561657	26	23	HGNC:6192	Pyrrolopyrimidine compound	Centaurus Biophrama Co., Ltd.; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562891	435	427		Quinazolinones as PARP14 inhibitors	Ribon Therapeutics Inc.	11/22/20	2D 3D TSV
US10561655	27	27	HGNC:9644	SHP2 inhibitors and uses thereof	SYNBLia Therapeutics, Inc.	11/22/20	2D 3D TSV
US10562916	209	206	HGNC:8772	Substituted quinoxalines as PDE-10 inhibitors	Sunovion Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562887	182	177	HGNC:10252	Triazolones and tetrazolones as inhibitors of ROCK	Bristol-Myers Squibb Company	11/22/20	2D 3D TSV
US10577367	528	508	HGNC:17967	IRAK4 inhibiting agents	BIOGEN MA INC.	11/21/20	2D 3D TSV
US10550117	11	11	HGNC:6853	2-azabicyclo[3.1.0]hexan-3-one derivatives and methods of use	Genentech, Inc.	11/20/20	2D 3D TSV
US10577353	28	27		5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO.5) LIMITED	11/20/20	2D 3D TSV
US10577360	308	153	HGNC:8156 HGNC:1399	Arylamide derivatives having multimodal activity against pain	ESTEVE PHARMACEUTICALS, S.A.	11/20/20	2D 3D TSV
US10577354	6	6		Bis-pyridazine compounds and their use in treating cancer	Cancer Research Technology Limited	11/20/20	2D 3D TSV
US10577352	67	37	HGNC:3236	Cot modulators and methods of use thereof	Gilead Sciences, Inc.	11/20/20	2D 3D TSV
US10577361	69	33	HGNC:3023 HGNC:3024	Dopamine D3 receptor antagonists having a morpholine moiety	INDIVIOR UK LIMITED	11/20/20	2D 3D TSV
US10550140	43	43	HGNC:2771	Ether compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals, Inc.	11/20/20	2D 3D TSV
US10576087	116	58		Fused tricyclic compounds as Raf kinase inhibitors	BEIGENE, LTD.	11/20/20	2D 3D TSV
US10550102	161	159		Indane and indoline derivatives and the use thereof as soluble guanylate cyclase activators	NOVARTIS AG	11/20/20	2D 3D TSV
US10550127	20	20	HGNC:4498	Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10550118	56	24	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	Theravance Biopharma R&D IP, LLC	11/20/20	2D 3D TSV
US10550114	65	21	HGNC:391	Kinase inhibitors and their use in cancer therapy	TECHNISCHE UNIVERSITÄT DORTMUND	11/20/20	2D 3D TSV
US10577330	196	28	HGNC:6160 HGNC:6161 HGNC:6163 HGNC:6141 HGNC:6156	Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists	Saint Louis University	11/20/20	2D 3D TSV
US10577336	169	87	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10544150	223	221	HGNC:11528	NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders	Ogeda SA	11/20/20	2D 3D TSV
US10550125	10	5	HGNC:2459 HGNC:2457	Prodrugs of imidazotriazine compounds as CK2 inhibitors	Bristol-Myers Squibb Company	11/20/20	2D 3D TSV
US10550105	855	803		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics Inc.	11/20/20	2D 3D TSV
US10577308	216	36	HGNC:10588 HGNC:10596	Sodium channel modulators	The Florey Institute; The University of Melbourne	11/20/20	2D 3D TSV
US10576064	115	107		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10577363	985	980		Substituted piperidine compounds	EPIZYME, INC.	11/20/20	2D 3D TSV
US10550096	5	3	HGNC:10894	Tetrahydroisoquinolines as PRMT5 inhibitors	CTXT PTY LTD	11/20/20	2D 3D TSV
US10556883	18	9	HGNC:195 HGNC:7155	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine and cosmetics	GALDERMA RESEARCH & DEVELOPMENT	11/13/20	2D 3D TSV
US10556902	124	122	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	11/13/20	2D 3D TSV
US10556885	634	302	HGNC:4617 HGNC:3091	Isoquinolin-3-YL carboxamides and preparation and use thereof	Samumed, LLC	11/13/20	2D 3D TSV
US10556892	65	37	HGNC:736	Piperazinyl methanone NAAA inhibitors	The Regents of the University of California; Fondazione Istituto Italiano di Technologia	11/13/20	2D 3D TSV
US10556908	120	119	HGNC:29079	Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors	Incyte Corporation	11/13/20	2D 3D TSV
US10556914	100	100	HGNC:4507	Substituted isoxazolopyridazinones and isothiazolopyridazinones and methods of use	ABBVIE INC.; ABBVIE DEUTSCHLAND GMBH & CO. KG	11/13/20	2D 3D TSV
US10555944	1229	556		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Eli Lilly and Company	11/13/20	2D 3D TSV
US10556900	75	71	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp.	11/13/20	2D 3D TSV
US10538491	153	153		4,5-substituted picolinamide and picolinonitrile metabotropic glutamate receptor 2 negative allosteric modulators	Vanderbilt University	11/09/20	2D 3D TSV
US10538523	3	3	HGNC:4076	4-(biphen-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I) as GABA receptor modulators for use in the treatment of epilepsy and pain	PFIZER LIMITED	11/09/20	2D 3D TSV
US10538528	107	46	HGNC:391 HGNC:10430	5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative	Taiho Pahrmaceutical Co., Ltd.	11/09/20	2D 3D TSV
US10538497	213	208	HGNC:6059	Compounds as indoleamine 2,3-dioxygenase inhibitors	Merck Sharp & Dohme Corp.	11/09/20	2D 3D TSV
US10538496	192	188	HGNC:19086	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.	11/09/20	2D 3D TSV
US10537571	140	66	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	EISAI R&D MANAGEMENT CO., LTD.	11/09/20	2D 3D TSV
US10538517	40	39	HGNC:3688	Quinolone derivatives as FGFR inhibitors	Principia Biopharma, Inc.	11/09/20	2D 3D TSV
US10538508	126	61	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics S.A.	11/09/20	2D 3D TSV
US10550091	176	87	HGNC:7968	1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor	St. Jude Children''s Research Hospital	11/07/20	2D 3D TSV
US10550100	455	114	HGNC:7160 HGNC:195 HGNC:7159 HGNC:221	5-[3-[piperzin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating E.G. osteoarthritis	GALAPAGOS NV	11/07/20	2D 3D TSV
US10548313	35	34		Acetyl-CoA carboxylase modulators	Monsanto Technology LLC	11/07/20	2D 3D TSV
US10550080	137	49	HGNC:10593 HGNC:10597	Acyl sulfonamide NaV1.7 inhibitors	Bristol-Myers Squibb Company	11/07/20	2D 3D TSV
US10550073	35	25	HGNC:2623 HGNC:6876	Benzamide derivative	CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.	11/07/20	2D 3D TSV
US10550089	124	62	HGNC:3538	Inhibitors of protease-activated receptor-2	Heptares Therapeutics Limited	11/07/20	2D 3D TSV
US10544132	133	130	HGNC:6973	Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity	ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED	11/07/20	2D 3D TSV
US10548897	8	8		KSR antagonists	Icahn School of Medicine at Mount Sinai	11/07/20	2D 3D TSV
US10544136	207	163	HGNC:3167 HGNC:3165	Modulators of sphingosine phosphate receptors	The Scripps Research Institute	11/07/20	2D 3D TSV
US10550099	297	182		Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors	Forma Therapeutics, Inc.	11/07/20	2D 3D TSV
US10548896	122	119	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/07/20	2D 3D TSV
US10544143	3210	878	HGNC:15633 HGNC:15631 HGNC:15632	4-azaindole compounds	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10544152	10	9	HGNC:5295	5-HT2CR agonist analogs	The Board of Regents of The University of Texas System; University of Houston System	11/02/20	2D 3D TSV
US10544146	4	1		Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors	FEDORA PHARMACEUTICALS INC.	11/02/20	2D 3D TSV
US10544151	11	11	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	11/02/20	2D 3D TSV
US10544141	90	76		Derivatives and methods of treating hepatitis B infections	NOVIRA THERAPEUTICS, INC.	11/02/20	2D 3D TSV
US10544133	168	150	HGNC:17967	Heteroaryl substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10533001	238	213	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11491	Inhibitors of protein kinases	PORTOLA PHARMACEUTICALS, INC.	11/02/20	2D 3D TSV
US10544128	732	235	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	11/02/20	2D 3D TSV
US10544130	1497	489		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10544147	185	117	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10533010	416	376	HGNC:6943 HGNC:992 HGNC:990	Substituted indole Mcl-1 inhibitors	Vanderbilt University	11/02/20	2D 3D TSV
US10544126	111	107		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases	TAKEDA PHARMACEUTICAL COMPANY LIMITED	11/02/20	2D 3D TSV
US10532048	12	12	HGNC:1113	Tetrahydroisoquinolin-1-one derivative or salt thereof	Seldar Pharma Inc.	11/02/20	2D 3D TSV
US10544095	38	38	HGNC:11708	3-indol substituted derivatives, pharmaceutical compositions and methods for use	Pfizer Inc.; iTeos Therapeutics	11/01/20	2D 3D TSV
US10544117	30	30	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University—Of The Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10543221	20	13		Beta-lactamase inhibitors, formulations, and uses thereof	University of South Florida; The Regents of the University of California	11/01/20	2D 3D TSV
US10544120	343	331	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	11/01/20	2D 3D TSV
US10544106	98	96	HGNC:1133	Certain chemical entities, compositions, and methods	NEUPHARMA, INC.	11/01/20	2D 3D TSV
US10544104	437	141	HGNC:4840 HGNC:11283 HGNC:76	Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO	11/01/20	2D 3D TSV
US10543207	74	73		Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders	ARDELYX, INC.	11/01/20	2D 3D TSV
US10544075	8	4	HGNC:11799 HGNC:11796	Derivatives of sobetirome	OREGON HEALTH & SCIENCE UNIVERSITY	11/01/20	2D 3D TSV
US10543198	75	75	HGNC:29079	Inhibitor of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10543199	18	5	HGNC:427	Macrocycle and composition comprising thereof	Shenzhen TargetRx, Inc.	11/01/20	2D 3D TSV
US10543194	6	6		Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/01/20	2D 3D TSV
US10544110	36	35	HGNC:644	Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer	University of Pittsburgh—Of the Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10544113	206	201	HGNC:5302	Thiazolidinone compounds and use thereof	National Health Research Institute; Regents of the University of Minnesota	11/01/20	2D 3D TSV
US10543183	12	6	HGNC:7966 HGNC:7965	Treatment and diagnosis of melanoma	The Rockefeller University	11/01/20	2D 3D TSV
US10543213	122	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10526325	98	57	HGNC:8810	Bicyclic heterocyclic derivatives	Merck Patent GmbH	10/25/20	2D 3D TSV
US10526329	367	214	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	10/25/20	2D 3D TSV
US10526336	212	98	HGNC:4849 HGNC:4848	Fused heteroaryl derivatives as orexin receptor antagonists	Merck, Sharp & Dohme Corp.	10/25/20	2D 3D TSV
US10526330	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	Theravance Biopharma R&D IP, LLC	10/25/20	2D 3D TSV
US10525036	90	58	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/25/20	2D 3D TSV
US10513534	17	11		2′-chloro nucleoside analogs for HCV infection	IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER	10/24/20	2D 3D TSV
US10513522	84	41	HGNC:6190 HGNC:6192	Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors	Incyte Corporation; Incyte Holdings Corporation	10/24/20	2D 3D TSV
US10512634	132	40	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	10/24/20	2D 3D TSV
US10513493	31	31	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	10/24/20	2D 3D TSV
US10513512	7	7	HGNC:3023	Flavanone derivatives, and preparation method and use thereof	Xuanwu Hospital of Capital Medical University	10/24/20	2D 3D TSV
US10513523	249	246	HGNC:4571	Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	10/24/20	2D 3D TSV
US10513499	22	22	HGNC:19288	Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase	TES Pharma S.r.l.	10/24/20	2D 3D TSV
US10513518	46	38	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp.	10/24/20	2D 3D TSV
US10512644	125	47	HGNC:8153 HGNC:8154 HGNC:8156	Oligomer-opioid agonist conjugates	Inheris Pharmaceuticals, Inc.	10/24/20	2D 3D TSV
US10513524	10	5	HGNC:8795 HGNC:8775	PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases	H. LUNDBECK A/S	10/24/20	2D 3D TSV
US10513514	34	32	HGNC:20001	Piperidine compounds as PCSK9 inhibitors	SHENZHEN SALUBRIS PHARM CO LTD.	10/24/20	2D 3D TSV
US10513507	13	11	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/24/20	2D 3D TSV
US10513520	6	6	HGNC:4912	Sulfamide and sulfamate inhibitors of hHint1	Regents of the University of Minnesota	10/24/20	2D 3D TSV
US10519167	3	3	HGNC:10894	3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	10/19/20	2D 3D TSV
US10519153	34	11	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Fused imidazo-piperidine JAK inhibitors	Theravance Biopharma R&D IP, LLC	10/19/20	2D 3D TSV
US10519177	802	696		Heterocyclic compounds and uses thereof	Plexxikon Inc.	10/19/20	2D 3D TSV
US10519118	167	165	HGNC:29079	KDM1A inhibitors for the treatment of disease	Imago Biosciences, Inc.	10/19/20	2D 3D TSV
US10517849	9	9	HGNC:29079	LSD1 inhibitors and medical uses thereof	Constellation Pharmaceuticals, Inc.	10/19/20	2D 3D TSV
US10517872	30	15	HGNC:17967	Pyridazinone macrocycles as IRAK inhibitors and uses thereof	Merck Patent GmbH	10/19/20	2D 3D TSV
US10519163	252	89	HGNC:7027 HGNC:12446	Pyrrolopyrimidine derivatives as TAM inhibitors	Incyte Corporation	10/19/20	2D 3D TSV
US10517878	110	106	HGNC:6871	Serine/threonine kinase inhibitors	GENENTECH, INC.	10/19/20	2D 3D TSV
US10517858	327	107	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as PIM kinase inhibitors	Incyte Holdings Corporation; Incyte Corporation	10/19/20	2D 3D TSV
US10512632	603	190	HGNC:8775 HGNC:8774 HGNC:8776	1 H-pyrazolo[4,3-B]pyridines as PDE1 inhibitors	H. Lundbeck A/S	10/18/20	2D 3D TSV
US10508119	51	49	HGNC:436	Pyrazole derivatives useful as 5-lipdxygenase activating protein (FLAP) inhibitors	ASTRAZENECA AB	10/18/20	2D 3D TSV
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US10508115	134	73	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	10/18/20	2D 3D TSV
US10508104	531	514	HGNC:339	6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501438	16	16	HGNC:13575	Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals	Neomed Institute	10/12/20	2D 3D TSV
US10508103	138	51	HGNC:11892	Benzimidazole-linked indole compound acting as novel divalent IAP antagonist	MEDSHINE DISCOVERY INC.	10/12/20	2D 3D TSV
US10508109	306	303	HGNC:17287	Bicyclic compound and use thereof for inhibiting SUV39H2	ONCOTHERAPY SCIENCE, INC.	10/12/20	2D 3D TSV
US10501436	207	36	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	Compounds and methods of use	Medivation Technologies LLC	10/12/20	2D 3D TSV
US10500194	30	30		Covalent small molecule DCN1 inhibitors and therapeutic methods using the same	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	10/12/20	2D 3D TSV
US10501473	12	12		Fused heterocyclic ring compounds and method of treating retinal disease using same	THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)	10/12/20	2D 3D TSV
US10501467	122	66	HGNC:270 HGNC:272 HGNC:15677 HGNC:273	Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors	BEIGENE, LTD.	10/12/20	2D 3D TSV
US10501440	42	26	HGNC:6371	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	10/12/20	2D 3D TSV
US10508105	148	117	HGNC:4596	Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/12/20	2D 3D TSV
US10508102	28	13	HGNC:11892	Inhibitors of cellular necrosis and related methods	President and Fellows of Harvard College; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences	10/12/20	2D 3D TSV
US10508099	951	303	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	10/12/20	2D 3D TSV
US10501452	149	37	HGNC:3023	Lactam compound derivative and application thereof	NHWA PHARMA. CORPORATION	10/12/20	2D 3D TSV
US10508107	58	20	HGNC:6251 HGNC:17734 HGNC:11049	Morpholine derivative	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501451	28	15		Selective NR2B antagonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501411	555	283		Substituted benzamides	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501458	72	37	HGNC:11708 HGNC:6059	Substituted bicyclic fused ring compounds as indoleamine-2,3-dioxygenase inhibitors	Iomet Pharma Ltd.; Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501449	69	68	HGNC:6255	Substituted nitrogen containing compounds	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501435	18	5	HGNC:4177	Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity	Northwestern University	10/12/20	2D 3D TSV
US10508108	131	121		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501466	33	33	HGNC:12757	WDR5 inhibitors and modulators	Vanderbilt University	10/12/20	2D 3D TSV
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US10508088	214	193	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10494380	32	31	HGNC:2623	Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity	Shionogi & Co., Ltd.	10/02/20	2D 3D TSV
US10508086	253	218	HGNC:8605 HGNC:270	PARG inhibitory compounds	Cancer Research Technology Limited	10/02/20	2D 3D TSV
US10507209	33	11	HGNC:3432 HGNC:3430 HGNC:3236	Quinazoline derivatives substituted by aniline, preparation method and use thereof	XUANZHU PHARMA CO, LTD.	10/02/20	2D 3D TSV
US10508098	13	13	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10493060	92	59	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/02/20	2D 3D TSV
US10508083	266	256	HGNC:4849	Substituted piperidine compound and use thereof	Takeda Pharmaceutical Company Limited	10/02/20	2D 3D TSV
US10494376	120	118	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD.	10/02/20	2D 3D TSV
US10479795	816	404	HGNC:8978 HGNC:8977	Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines and substituted imidazo[1,2-b]pyridazines as PI3K-gamma inhibitors	Incyte Corporation	09/26/20	2D 3D TSV
US10479803	38	29	HGNC:6190 HGNC:8977	Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors	Incyte Corporation	09/25/20	2D 3D TSV
US9975885	182	31		Broad-spectrum non-covalent coronavirus protease inhibitors	PURDUE RESEARCH FOUNDATION	09/25/20	2D 3D TSV
US10479788	156	155	HGNC:12401	Compounds that inhibit MPS1 kinase	Cancer Research Technology Limited	09/25/20	2D 3D TSV
US10479794	202	66	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	09/25/20	2D 3D TSV
US10478426	8	7		Enhancer of Zeste Homolog 2 inhibitors	GLAXOSMITHKLINE LLC	09/25/20	2D 3D TSV
US10479798	32	32	HGNC:3009	Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof	EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	09/25/20	2D 3D TSV
US10479784	603	576	HGNC:882	Substituted pyrazin-2-amines as inhibitors of ATR kinase	VERTEX PHARMACEUTICALS INCORPORATED	09/25/20	2D 3D TSV
US10478424	2922	955	HGNC:15633 HGNC:15631 HGNC:15632	[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds	Bristol-Myers Squibb Company	09/24/20	2D 3D TSV
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US10487111	12	12	HGNC:10906	IBAT inhibitors for the treatment of liver diseases	Albireo AB	09/20/20	2D 3D TSV
US10487086	77	77	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10485800	204	202	HGNC:6850	Mixed lineage kinase inhibitors for HIV/AIDS therapies	The University of Rochester; Board of Regents of the University of Nebraska	09/20/20	2D 3D TSV
US10487087	38	25	HGNC:4324	Positive allosteric modulators of the GLP-1 receptor	Vanderbilt University	09/20/20	2D 3D TSV
US10487092	126	124		Pyrazolopyridinamines as MKNK1 and MKNK2 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	09/20/20	2D 3D TSV
US10485803	106	42	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrimidine compounds as JAK kinase inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	09/20/20	2D 3D TSV
US10487083	60	15		Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	09/20/20	2D 3D TSV
US10478423	74	37	HGNC:6342 HGNC:3765	Substituted indazole derivatives active as kinase inhibitiors	NERVIANO MEDICAL SCIENCES S.R.L.	09/20/20	2D 3D TSV
US10487084	22	13	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10472354	838	389	HGNC:8534	1,3-thiazol-2-yl substituted benzamides	Bayer Aktiengesellschaft	09/14/20	2D 3D TSV
US10472358	196	86		1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	09/14/20	2D 3D TSV
US10472324	9	9		2-cyano-3-cyclopropyl-3-hydroxy-N-aryl-thioacrylamide derivatives	ALGIAX PHARMACEUTICALS GMBH	09/14/20	2D 3D TSV
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US10472367	5	5	HGNC:7029	Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors	INCYTE INCORPORATION; INCYTE HOLDINGS CORPORATION	09/14/20	2D 3D TSV
US10464947	570	277	HGNC:13575	Tricyclic heterocycles as BET protein inhibitors	Incyte Holdings Corporation; Incyte Corporation	09/09/20	2D 3D TSV
US10464911	88	76	HGNC:4852 HGNC:14064	1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same	Chong Kun Dang Pharmaceutical Corp.	09/08/20	2D 3D TSV
US10464927	98	49	HGNC:1777 HGNC:1773	2,4-disubstituted pyrimidines as CDK inhibitors	Shanghai Xunhe Pharmaceutical Technology Co. Ltd.	09/08/20	2D 3D TSV
US10464928	3	3	HGNC:550	Amino pyrimidine SSAO inhibitors	Eli Lilly and Company	09/08/20	2D 3D TSV
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US10464907	29	29		Compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof	INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY	09/08/20	2D 3D TSV
US10464902	10	10	HGNC:6307	Multi-tyrosine kinase inhibitors derivatives and methods of use	Ontogenesis, LLC	09/08/20	2D 3D TSV
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US10463663	68	66	HGNC:2671	Pyridazinone compounds and their use as DAAO inhibitors	Takeda Pharmaceutical Company Limited	09/08/20	2D 3D TSV
US10464919	346	184	HGNC:270 HGNC:19297 HGNC:11940	Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same	Je Il Pharmaceutical Co., Ltd.	09/08/20	2D 3D TSV
US10457637	170	120	HGNC:5981	Benzenesulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (RORγ(T))	GALDERMA RESEARCH & DEVELOPMENT	09/07/20	2D 3D TSV
US10457678	10	10	HGNC:195	Substituted pyrrolo[2,3-b]pyridines as inhibitors of cellular necroptosis	Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1	09/07/20	2D 3D TSV
US10457681	16	11	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor	Bristol_Myers Squibb Company	09/07/20	2D 3D TSV
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US10457685	76	38	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-D]pyrimidine derivatives with affinity for the type-2 cannabinoid receptor	Hoffmann-La Roche Inc.	09/07/20	2D 3D TSV
US10457684	30	15	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-d]pyrimidine derivatives	Hoffmann-La Roche Inc.	09/07/20	2D 3D TSV
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US10450313	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Holdings Corporation	08/31/20	2D 3D TSV
US10450298	7	6	HGNC:3357	PET Imaging agents	Novartis AG	08/31/20	2D 3D TSV
US10450297	341	328		Sulfonyl amide derivatives for the treatment of abnormal cell growth	Pfizer, Inc.	08/31/20	2D 3D TSV
US10450321	14	7	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-D]pyrimidine derivatives	Hoffmann-La Roche Inc.	08/31/20	2D 3D TSV
US10450296	510	168	HGNC:19310 HGNC:8987	Heterocyclic compounds useful as Pim kinase inhibitors	Incyte Corporation	08/30/20	2D 3D TSV
US10457672	128	128	HGNC:15983	γ-diketones as Wnt/β-catenin signaling pathway activators	Samumed, LLC	08/24/20	2D 3D TSV
US10323028	67	55		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	08/24/20	2D 3D TSV
US10442759	21	21		1-sulfonamido-4-aryloxy compounds, and preparation method and medicinal application thereof	CHINA PHARMACEUTICAL UNIVERSITY	08/24/20	2D 3D TSV
US10457647	40	40	HGNC:1133	Amino pyrimidine derivatives	Novartis AG	08/24/20	2D 3D TSV
US10323037	118	118	HGNC:1133	Aminopyridazinone compounds as protein kinase inhibitors	JIANGSU HENGRUI MEDICINE CO., LTD.	08/24/20	2D 3D TSV
US10435408	19	19	HGNC:5302	Azepine derivatives as 5-HT7 receptor modulators	Korea Institute of Science and Technology	08/24/20	2D 3D TSV
US10377755	15	15	HGNC:990	BCL-2 inhibitors	Newave Pharmaceutical Inc.	08/24/20	2D 3D TSV
US10442772	248	182		Benzimidazol-2-amines as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	08/24/20	2D 3D TSV
US10457669	927	912	HGNC:6871	Benzolactam compounds as protein kinase inhibitors	OTSUKA PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10307425	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	08/24/20	2D 3D TSV
US10376513	368	348	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	08/24/20	2D 3D TSV
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US10457677	471	137	HGNC:8979 HGNC:8978 HGNC:795 HGNC:3942	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	08/24/20	2D 3D TSV
US10323013	21	21	HGNC:3449	Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.	08/24/20	2D 3D TSV
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US10399948	138	60		Negative allosteric modulators of metabotropic glutamate receptor 3	Vanderbilt University	08/24/20	2D 3D TSV
US10456385	31	31	HGNC:1960	Pharmaceutical composition comprising pyridone derivatives	SK BIOPHARMACEUTICALS CO., LTD.	08/24/20	2D 3D TSV
US10399980	544	539	HGNC:12607	Purinones as ubiquitin-specific protease 1 inhibitors	FORMA Therapeutics, Inc.	08/24/20	2D 3D TSV
US10442808	127	124		Pyrazolo pyrimidine derivatives and their use as MALT1 inhbitors	Novartis AG	08/24/20	2D 3D TSV
US10329300	80	80	HGNC:3430	Pyrazolo[3,4-d]pyrimidine compound or salt thereof	TAIHO PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10442810	438	145	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as TAM inhibitors	Incyte Corporation	08/24/20	2D 3D TSV
US10301261	220	104		Substituted indoles as modulators of ROR-gamma	Vitae Pharmaceuticals, LLC	08/24/20	2D 3D TSV
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US10442819	556	509		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	08/24/20	2D 3D TSV
US10442803	546	273	HGNC:13575	Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	08/24/20	2D 3D TSV
US9951068	213	154	HGNC:6251 HGNC:550	Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors	PROXIMAGEN LIMITED	08/19/20	2D 3D TSV
US10428066	213	155	HGNC:6251 HGNC:550	Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors	PROXIMAGEN, LLC	08/19/20	2D 3D TSV
US10428044	491	480	HGNC:1148	3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones	Bayer Pharma Aktiengesellschaft	08/17/20	2D 3D TSV
US10428063	47	46		4H-pyrrolo[3,2-C]pyridin-4-one derivatives	Bayer Pharma Aktiengesellschaft	08/17/20	2D 3D TSV
US10435406	8	5	HGNC:8154 HGNC:8156	6,7-cyclicmorphinan derivatives and use thereof	Purdue Pharma L.P.	08/17/20	2D 3D TSV
US10428108	98	93		Difluoroketamide derivatives	Hoffmann-La Roche Inc.	08/17/20	2D 3D TSV
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US10428083	23	6	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor	BAYER PHARMA AKTIENGESELLSCHAFT	08/17/20	2D 3D TSV
US10426135	104	104		Methyl- and trifluromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof	Pfizer Inc.	08/17/20	2D 3D TSV
US10428024	85	52	HGNC:8810	Piperidinyl derivatives	MERCK PATENT GMBH	08/17/20	2D 3D TSV
US10428087	125	82	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Corporation	08/17/20	2D 3D TSV
US10428074	130	69	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrole heteroaryl ring derivative and method of use thereof	Jiangsu Hengrui Medicine Co., Ltd.	08/17/20	2D 3D TSV
US10428076	247	231		Soluble guanylate cyclase stimulators	Merck Sharp & Dohme Corp.	08/17/20	2D 3D TSV
US10428104	118	117	HGNC:10894	Substituted nucleoside derivatives useful as anticancer agents	Pfizer Inc.	08/17/20	2D 3D TSV
USRE47636	27	27	HGNC:2528	Substituted spirocycles	Boehringer Ingelheim International GmbH	08/17/20	2D 3D TSV
US10435415	152	43	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Company	08/17/20	2D 3D TSV
US10435407	170	169	HGNC:2730	Triaza-spirodecanones as DDR1 inhibitors	Hoffmann-La Roche Inc.	08/17/20	2D 3D TSV
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US10435400	122	57	HGNC:3236	2,4-disubstituted phenylene-1,5-diamine derivatives and applications thereof, and pharmaceutical compositions and pharmaceutically acceptable compositions prepared therefrom	SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO. LTD.	08/16/20	2D 3D TSV
US10435396	47	47	HGNC:17967	2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs	Bayer Pharma Aktiegesellschaft	08/16/20	2D 3D TSV
US10435392	28	13		Bipyrazole derivatives as JAK inhibitors	Incyte Corporation	08/16/20	2D 3D TSV
US10434101	94	47	HGNC:3236	Heterocyclic compounds and uses thereof	Celgene CAR LLC	08/16/20	2D 3D TSV
US10435355	26	13	HGNC:3553	Inhibitors of fatty acid amide hydrolase (FAAH) enzyme with improved oral bioavailability and their use as medicaments	The Regents of the University of California	08/16/20	2D 3D TSV
US10435361	318	118	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Topivert Pharma Limited	08/16/20	2D 3D TSV
US10434085	15	14	HGNC:6859	Non-aromatic difluoro analogues of resorcylic acid lactones	University of North Carolina at Greensboro	08/16/20	2D 3D TSV
US10435398	70	33	HGNC:4849 HGNC:4848	Oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp.	08/16/20	2D 3D TSV
US10435405	241	235	HGNC:6863	Pyrazolopyridine compounds and uses thereof	Incyte Corporation	08/16/20	2D 3D TSV
US10435369	304	268		Tricyclic sulfones as ROR gamma modulators	Bristol-Myers Squibb Company	08/16/20	2D 3D TSV
US10434112	188	179	HGNC:3827	Use of agonists of formyl peptide receptor 2 for treating dermatological diseases	ALLERGAN, INC.	08/16/20	2D 3D TSV
US10435379	9	9	HGNC:6018	[4-(1,3,3-trimethyl-2-OXO-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or salt thereof	SANTEN PHARMACEUTICAL CO., LTD.	08/16/20	2D 3D TSV
US10421756	152	74	HGNC:4852 HGNC:4853	Heterobicyclic N-aminophenyl-amides as inhibitors of histone deacetylase	Rodin Therapeutics, Inc.	08/12/20	2D 3D TSV
US10421760	61	20	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolo[2,3-d]pyrimidine compound or salt thereof	TAIHO PHARMACEUTICAL CO., LTD.	08/12/20	2D 3D TSV
US10420768	72	22	HGNC:4586 HGNC:6251 HGNC:2625	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	08/12/20	2D 3D TSV
US10421747	35	7	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Quinoxaline derivatives useful as FGFR kinase modulators	ASTEX THERAPEUTICS LTD	08/12/20	2D 3D TSV
US10421750	47	47	HGNC:8157	Substituted morpholine derivatives having activity against pain	ESTEVE PHARMACEUTICALS, S.A.	08/12/20	2D 3D TSV
US10421742	516	252	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives	BAYER PHARMA AKTIENGESELLSCHAFT	08/12/20	2D 3D TSV
US10421722	9	9	HGNC:10936	Sulfur-containing compounds targeting vesicular acetylcholine transporter	Washington University	08/12/20	2D 3D TSV
US10421743	3	3	HGNC:10894	Tetrahydroisoquinolines as PRMT5 inhibitors	CTXT PTY LTD	08/12/20	2D 3D TSV
US10421765	101	99		Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase	Board of Regents, The University of Texas System	08/12/20	2D 3D TSV
US10414734	32	27		5-hydroxyalkylbenzimidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10413562	298	295	HGNC:1133	Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity	Merck Patent GmbH	08/02/20	2D 3D TSV
US10414761	375	111	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Company Limited	08/02/20	2D 3D TSV
US10414797	100	23	HGNC:7173 HGNC:7174 HGNC:7176 HGNC:7155	Gelatinase inhibitors and use thereof	Iproteos S.L	08/02/20	2D 3D TSV
US10413545	98	97	HGNC:3594	Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer	Janssen Pharmaceutica NV	08/02/20	2D 3D TSV
US10413550	137	136		Isoxazole compounds as inhibitors of heat shock proteins	The Institute of Cancer Research	08/02/20	2D 3D TSV
US10414731	16	16	HGNC:3529	Substituted oxopyridine derivatives	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10414765	104	48	HGNC:6283 HGNC:6278	Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10399985	41	41	HGNC:8772	(Hetero)aryl imidazoles/pyrazoles for treatment of neurological disorders	Hoffmann-La Roche Inc.	07/27/20	2D 3D TSV
US10407409	426	417		6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD	Takeda Pharmaceutical Company Limited	07/27/20	2D 3D TSV
US10407446	78	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11393 HGNC:11390 HGNC:12401	Amino-triazolopyridine compounds and their use in treating cancer	AstraZeneca AB	07/27/20	2D 3D TSV
US10406136	18	9		Composition for suppressing neuraminidase activity comprising geranylated flavonoid derived from Paulownia tomentosa as active ingredient	INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY	07/27/20	2D 3D TSV
US10407441	14	7		Compositions and methods for treating neoplasia, inflammatory disease and other disorders	Dana-Farber Cancer Institute, Inc.	07/27/20	2D 3D TSV
US10399973	27	27	HGNC:550	Compounds I	BENEVOLENTAI CAMBRIDGE LIMITED	07/27/20	2D 3D TSV
US10407431	34	34	HGNC:15631	Compounds and compositions as toll-like receptor 7 agonists	Novartis AG	07/27/20	2D 3D TSV
US10407423	40	23	HGNC:2976 HGNC:14129	Compounds as inhibitors of DNA methyltransferases	FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA	07/27/20	2D 3D TSV
US10399967	143	139	HGNC:6001	Compounds for inflammation and immune-related uses	PRCL RESEARCH INC.	07/27/20	2D 3D TSV
US10399976	220	153		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	07/27/20	2D 3D TSV
US10398702	108	27		Dimeric compounds	Hoffmann-La Roche Inc.	07/27/20	2D 3D TSV
US10399961	15	15	HGNC:6371	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	07/27/20	2D 3D TSV
US10398706	9	7		Heteroaryldiazepine derivatives as RSV inhibitors	Enanta Pharmaceuticals, Inc.	07/27/20	2D 3D TSV
US10399979	92	23	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Janus kinase inhibitors and uses thereof	Purdue Research Foundation	07/27/20	2D 3D TSV
US10399991	64	64	HGNC:6221	Kv1.3 inhibitors and their medical applications	4SC AG	07/27/20	2D 3D TSV
US10399974	57	57	HGNC:12401	N2-phenyl-pyrido[3,4-D]pyrimidine-2, 8-diamine derivatives and their use as Mps1 inhibitors	Cancer Research Technology Limited	07/27/20	2D 3D TSV
US10399958	21	21	HGNC:9235	PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof	Mitobridge, Inc.	07/27/20	2D 3D TSV
US10399989	279	96	HGNC:1133 HGNC:3236	Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer	Loxo Oncology, Inc.	07/27/20	2D 3D TSV
US10407433	124	111	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	The Trustees of Columbia University In The City of New York	07/27/20	2D 3D TSV
US10399987	98	49	HGNC:11773	TGF beta receptor antagonists	Bristol-Myer Squibb Company	07/27/20	2D 3D TSV
US10399939	40	40	HGNC:3467	Tetrahydronaphthalene estrogen receptor modulators and uses thereof	Genentech, Inc.	07/27/20	2D 3D TSV
US10399945	74	68	HGNC:8031	Tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	07/27/20	2D 3D TSV
US10406157	4	2	HGNC:4515	Tetrahydropyridopyrazine modulators of GPR6	Takeda Pharmaceutical Company Limited	07/27/20	2D 3D TSV
US10398703	23	23	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	07/27/20	2D 3D TSV
US10407422	9	9	HGNC:7218	Triazolopyridine inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	07/27/20	2D 3D TSV
US10399972	70	66		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	07/27/20	2D 3D TSV
US10392391	570	547	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Incorporated	07/20/20	2D 3D TSV
US10392402	22	11	HGNC:10251 HGNC:10252	Heterocyclic compounds as kinase inhibitors	Translational Drug Development, LLC	07/20/20	2D 3D TSV
US10392376	131	119		Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System	07/20/20	2D 3D TSV
US10392346	187	72	HGNC:11491 HGNC:11283 HGNC:4616	Kinase inhibitors	Topivert Pharma Limited	07/20/20	2D 3D TSV
US10392405	25	25	HGNC:17635	Macrocyclic immunomodulators	ChemoCentryx, Inc.	07/20/20	2D 3D TSV
US10391089	334	330	HGNC:29652	PRMT5 inhibitors and uses therof	Epizyme, Inc.	07/20/20	2D 3D TSV
US10392392	120	103	HGNC:6251	Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors	Tolero Pharmaceuticals, Inc.	07/20/20	2D 3D TSV
US10385022	323	323	HGNC:19680	3-amino-pyridines as GPBAR1 agonists	HOFFMANN-LA ROCHE INC.	07/13/20	2D 3D TSV
US10383871	19	19	HGNC:3553	Azetidine derivatives	Vernalis (R&D) Ltd.	07/13/20	2D 3D TSV
US10383880	247	237	HGNC:8846	Carbazole-containing sulfonamides as cryptochrome modulators	Synchronicity	07/13/20	2D 3D TSV
US10385066	36	35	HGNC:2843	Compounds as diacylglycerol acyltransferase inhibitors	GlaxoSmithKline LLC	07/13/20	2D 3D TSV
US10383850	23	23		Indazole and indole derivatives as inhibitors of retinoic acid related orphan receptor gamma (ROR gamma) for the treatment of immune-related diseases	ORCA PHARMACEUTICALS LIMITED	07/13/20	2D 3D TSV
US10377772	63	63	HGNC:18618	Macrocyclic LRRK2 kinase inhibitors	Oncodesign S.A.	07/13/20	2D 3D TSV
US10377763	48	23	HGNC:4849 HGNC:4848	Morphinan derivative and medical usage thereof	UNIVERSITY OF TSUKUBA	07/13/20	2D 3D TSV
US10385031	171	56	HGNC:4852 HGNC:4854 HGNC:4853	Substituted piperazines as selective HDAC1,2 inhibitors	REGENACY PHARMACEUTICALS, LLC	07/13/20	2D 3D TSV
US10385036	35	35		Sulfonamide-substituted indole modulators of RORC2 and methods of use thereof	Pfizer Inc.	07/13/20	2D 3D TSV
US10377768	112	91		Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation	07/13/20	2D 3D TSV
US10383835	72	25	HGNC:3401	Treatment of inflammatory disorders in non-human mammals	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	07/13/20	2D 3D TSV
US10385052	28	7	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Tricyclic compound and JAK inhibitor	Nissan Chemical Corporation	07/13/20	2D 3D TSV
US10377770	457	419		Tricyclic compounds and compositions as kinase inhibitors	Novartis AG	07/13/20	2D 3D TSV
US10377742	493	490	HGNC:9377	AMPK-activating heterocyclic compounds and methods for using the same	Rigel Pharmaceuticals, Inc.	07/06/20	2D 3D TSV
US10370370	89	58	HGNC:5297 HGNC:1960	Aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors	Axovant Sciences GmbH	07/06/20	2D 3D TSV
US10370368	11	9	HGNC:6713	Aryl acylsulfonamides as BLT1 antagonists	Merck Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10370338	50	25	HGNC:15631 HGNC:15632	Benzazepine dicarboxamide compounds with tertiary amide function	Hoffmann-La Roche Inc.	07/06/20	2D 3D TSV
US10377729	5	5	HGNC:12405	Bis-furan derivatives as transthyretin (TTR) stabilizers and amyloid inhibitors for the treatment of familial amyloid polyneuropathy (FAP)	BSIM Therapeutics, S.A.	07/06/20	2D 3D TSV
US10370379	25	25	HGNC:8031	Compounds and compositions useful for treating disorders related to NTRK	BLUEPRINT MEDICINES CORPORATION	07/06/20	2D 3D TSV
US10370352	7	7	HGNC:6857	Cyclobutyl-imidazolidinone compounds	ELI LILLY AND COMPANY	07/06/20	2D 3D TSV
US10377717	104	104	HGNC:7967	Farnesoid X receptor agonists and uses thereof	METACRINE, INC.	07/06/20	2D 3D TSV
US10370388	85	82	HGNC:338	Heterocyclic compounds and methods of their use	NOVARTIS AG	07/06/20	2D 3D TSV
US10370375	84	28		Heterocyclyl-substituted cyclohexylsulfonamides as JAK inhibitors	Elanco Tiergesundheit AG	07/06/20	2D 3D TSV
US10377746	20	20		Indolin-2-one derivatives	Hoffmann-La Roche Inc.	07/06/20	2D 3D TSV
US10370339	48	47		N-Methylbenzimidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	07/06/20	2D 3D TSV
US10370337	5	5		Oxy-cyanoquinolinone PDE9 inhibitors	Merck, Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10370336	6	5		Phenyl-cyanoquinolinone PDE9 inhibitors	Merck Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10377744	62	55	HGNC:3402	Potent soluble epdxide hydrolase inhibitors	Eicosis, LLC	07/06/20	2D 3D TSV
US10369153	249	142	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolopyrimidine compounds and uses thereof	HUTCHISON MEDIPHARMA LIMITED	07/06/20	2D 3D TSV
US10370360	160	40	HGNC:6342 HGNC:2730 HGNC:2731	Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof	The Board of Regents of the University of Texas System	07/06/20	2D 3D TSV
US10377753	634	628	HGNC:4586	Substituted 4-azaindoles and their use as GluN2B receptor modulators	JANSSEN PHARMACEUTICA NV	07/06/20	2D 3D TSV
US10376531	17	17	HGNC:742	Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR	Pfizer Inc.	07/06/20	2D 3D TSV
US10370333	169	163	HGNC:438	Sulfonamide compounds and uses as TNAP inhibitors	SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	07/06/20	2D 3D TSV
US10370387	196	96		Tricyclic fused thiophene derivatives as JAK inhibitors	Incyte Holdings Corporation	07/06/20	2D 3D TSV
US10376502	20	20		Alkylated imino sugars exhibiting glucosidase inhibition and their method of use	TBA	06/29/20	2D 3D TSV
US10364255	43	41		Heteroaromatic compounds as Vanin inhibitors	Boehringer Ingleheim International GmbH	06/29/20	2D 3D TSV
US10364242	3	1	HGNC:3553 HGNC:736 HGNC:735	Modulation of N-acylethanolamine-hydrolysing acid amidase (NAAA) for disease treatment	Fondazione Istituto Italiano di Tecnologia	06/29/20	2D 3D TSV
US10364238	188	92	HGNC:6371 HGNC:6357	N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	Kalvista Pharmaceuticals Limited	06/29/20	2D 3D TSV
US10364234	5	2	HGNC:6251 HGNC:6255	Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof	Jiangsu Hengrui Medicine Co., Ltd.	06/29/20	2D 3D TSV
US10376504	6	6		Substituted quinolinones as PDE9 inhibitors	Merck Sharp & Dohme Corp	06/29/20	2D 3D TSV
US10376514	304	300	HGNC:8775	Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6H)-ones	Dart NeuroScience (Cayman) Ltd	06/29/20	2D 3D TSV
US10336729	95	95	HGNC:550	4-cyano-benzyl carbamimidoylcarbamate derivatives and their use as AOC3 inhibitors	Boehringer Ingelheim International GmbH	06/21/20	2D 3D TSV
US10336739	253	250	HGNC:339	4-hydroxy-3-(heteroaryl)pyridine-2-one APJ agonists	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10357546	20	10	HGNC:7175 HGNC:7176	Acceleration of diabetic wound healing	University of Notre Dame du Lac	06/21/20	2D 3D TSV
US10336733	50	46	HGNC:6713	Aryl acylsulfonamides as BLT1 antagonists	Merk Sharp & Dohme Corp.	06/21/20	2D 3D TSV
US10358446	67	16	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:6524	Bruton's tyrosine kinase inhibitors	ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO., LTD.	06/21/20	2D 3D TSV
US10336724	38	19	HGNC:2671	D-amino acid oxidase inhibitors and therapeutic uses thereof	SyneuRx International (Taiwan) Corp.	06/21/20	2D 3D TSV
US10336755	23	23	HGNC:1133	Fused pyrazole derivatives, preparation method thereof, and use thereof in treatment of cancers, inflammation and immune diseases	Beijing Innocare Pharma Tech Co., Ltd.	06/21/20	2D 3D TSV
US10336775	181	174	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	06/21/20	2D 3D TSV
US10358451	19	13	HGNC:11708 HGNC:6059	Heterocycles useful as IDO and TDO inhibitors	Hangzhou Innogate Pharma Co., Ltd.	06/21/20	2D 3D TSV
US10336727	237	79	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	06/21/20	2D 3D TSV
US10336734	12	3	HGNC:6192 HGNC:19297 HGNC:11283 HGNC:427	Inhibitors of ACK1/TNK2 tyrosine kinase	H. Lee Moffitt Cancer Center and Research Institute Inc	06/21/20	2D 3D TSV
US10358436	643	201	HGNC:11393 HGNC:11390 HGNC:3765	Kinase inhibitors and method of treating cancer	University Health Network	06/21/20	2D 3D TSV
US10357493	402	201	HGNC:4852 HGNC:14064	Metalloenzyme inhibitor compounds	Selenity Therapeutics (Bermuda), Ltd.	06/21/20	2D 3D TSV
US10336774	68	64	HGNC:9644	N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2	Novartis AG	06/21/20	2D 3D TSV
US10336754	22	8	HGNC:6371 HGNC:3529	Pyrimidinones as factor XIa inhibitors	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10336762	1932	935	HGNC:11892 HGNC:17967	Pyrrolo[1,2-b]pyridazine derivatives	Gilead Sciences Inc	06/21/20	2D 3D TSV
US10336759	26	26	HGNC:6190	Salts and processes of preparing a PI3K inhibitor	Incyte Corporation	06/21/20	2D 3D TSV
US10336731	14	14	HGNC:6059	Substituted 1H-indole-2-carboxamide compounds as indoleamine-2,3-dioxygenase inhibitors	Merck Sharp & Dohme Corp	06/21/20	2D 3D TSV
US10358416	288	286	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Epics Therapeutics	06/21/20	2D 3D TSV
US10336741	56	18	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases	Ono Pharmaceutical Co., Ltd	06/21/20	2D 3D TSV
US10336761	682	341	HGNC:11773	TGFβ receptor antagonist	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10336752	15	11	HGNC:12440	TYK2 inhibitors, uses, and methods for production thereof	Nimbus Lakshmi, Inc.	06/21/20	2D 3D TSV
US10336757	25	25	HGNC:1735	Treatment of neurodegenerative diseases through inhibition of HSP90	Sloan-Kettering Institute for Cancer Research	06/21/20	2D 3D TSV
US10358435	116	66		Triazolyl pyrimidinone compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	06/21/20	2D 3D TSV
US10358449	5	5	HGNC:3009	Xanthine derivative	Jiangsu Tasly Diyi Pharmaceutical Co, LTD.	06/21/20	2D 3D TSV
US10351548	11	11	HGNC:8816	2-oxo-1,2-dihydropyridine-3-carboxamide compounds and their use as inhibitors of PDK1	International Society for Drug Development S.R.L.	06/12/20	2D 3D TSV
US10351563	236	233	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Co.	06/12/20	2D 3D TSV
US10351575	161	158	HGNC:8031	Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain	Array BioPharma Inc	06/12/20	2D 3D TSV
US10351570	11	10	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	06/12/20	2D 3D TSV
US10351558	215	212	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	06/12/20	2D 3D TSV
US10351547	267	263	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	06/12/20	2D 3D TSV
US10343992	273	268		1-cyano-pyrrolidine compounds as USP30 inhibitors	Missions Therapeutics Limited	06/09/20	2D 3D TSV
USRE47493	273	267	HGNC:3309	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	06/09/20	2D 3D TSV
US10344000	39	35		Substituted bicyclic pyrazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	06/09/20	2D 3D TSV
US10344025	605	595		GLS1 inhibitors for treating disease	The University of Texas System	06/08/20	2D 3D TSV
US10344004	1	1		Inhibitor of the mutated isocitrate dehydrogenase IDH1 R132H	Bayer Pharma Aktiengesellschaft	06/08/20	2D 3D TSV
US10344034	19	13	HGNC:4421	Pyrazolopyrimidone or Pyrrolotriazone derivatives, method of preparing same, and pharmaceutical applications thereof	Shanghai Hengrui Pharmaceutical Co., Ltd	06/08/20	2D 3D TSV
US10342794	7	7	HGNC:11491	Substituted imidazo[1,2-a]pyrazines as Syk inhibitors	Gilead Sciences Inc	06/08/20	2D 3D TSV
US10016430	30	15	HGNC:7218 HGNC:12015	1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase	AstraZeneca AB	06/01/20	2D 3D TSV
USRE46942	106	38	HGNC:270 HGNC:11941 HGNC:272 HGNC:15677	4-piperidinyl compounds for use as tankyrase inhibitors	Novartis AG	06/01/20	2D 3D TSV
US10017516	326	67	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	BMP inhibitors and methods of use thereof	The Brigham and Women's Hospital, Inc.	06/01/20	2D 3D TSV
US10017501	84	42		Benzimidazole derivatives as bromodomain inhibitors	Gilead Sciences Inc	06/01/20	2D 3D TSV
US10017502	22	18		Benzoxazinone amides as mineralocorticoid receptor modulators	AstraZeneca AB	06/01/20	2D 3D TSV
US10016438	200	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	06/01/20	2D 3D TSV
US10016439	11	11	HGNC:4079	Fused imidazole compounds	Ono Pharmaceutical Co., Ltd	06/01/20	2D 3D TSV
US10017504	140	68	HGNC:4849 HGNC:4848	Piperidine isoxazole and isothiazole orexin receptor antagonists	Merck Sharp & Dohme Corp	06/01/20	2D 3D TSV
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US10336721	35	35	HGNC:7097	Biaryltriazole inhibitors of macrophage migration inhibitory factor	Yale University	05/31/20	2D 3D TSV
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US10329307	74	70		Heterocyclic compounds as inhibitors of platelet aggregation	Universite de Montreal	05/31/20	2D 3D TSV
US10329303	52	52	HGNC:23357	Heterocyclic inhibitors of monocarboxylate transporter	The Scripps Research Institute	05/31/20	2D 3D TSV
US10336717	549	510	HGNC:933	Inhibitors of beta-secretase	Vitae Pharmaceuticals, LLC	05/31/20	2D 3D TSV
US10335409	178	86		Inhibitors of hepatitis C virus	Gilead Pharmasset LLC	05/31/20	2D 3D TSV
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US10336684	60	53	HGNC:19061	Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators	Bristol=Myers Squibb Company	05/31/20	2D 3D TSV
US10329294	290	280	HGNC:17967	Pyrazolopyrimidine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	05/31/20	2D 3D TSV
US10329295	163	162	HGNC:17967	Pyrrolotriazine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	05/31/20	2D 3D TSV
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US10011599	101	99	HGNC:6840	Compounds and compositions as inhibitors of MEK	Novartis AG	05/26/20	2D 3D TSV
US10011568	40	21	HGNC:11526 HGNC:2637	Cyclohexyl pyridine derivative	Kissei Pharmaceutical Co., Ltd	05/26/20	2D 3D TSV
US10011595	242	120	HGNC:4849 HGNC:4848	Ethyldiamine orexin receptor antagonists	Merck Sharp & Dohme Corp	05/26/20	2D 3D TSV
US10011607	111	111	HGNC:4596	Ethynyl derivatives	Hoffman-La Roche Inc	05/26/20	2D 3D TSV
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US10011611	44	4	HGNC:4852 HGNC:14064 HGNC:19086 HGNC:14068 HGNC:13315 HGNC:4853 HGNC:18128	Histone deacetylase inhibitors and methods for use thereof	Reaction Biology Corp	05/26/20	2D 3D TSV
US10011604	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc	05/26/20	2D 3D TSV
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US10010539	216	108	HGNC:4848	Pyrazole, triazole and tetrazole orexin receptor antagonists	Merck Sharp & Dohme Corp	05/26/20	2D 3D TSV
US10005769	79	78	HGNC:3092	2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors	4SC AG	05/18/20	2D 3D TSV
US10005792	140	135	HGNC:10894	Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived PRMT5-inhibitors	CTXT PTY. LTD.	05/18/20	2D 3D TSV
US10005788	52	24	HGNC:7027 HGNC:12446	Bicyclic fused pyrimidine compounds as TAM inhibitors	Incyte Corporation	05/18/20	2D 3D TSV
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US10005735	104	40	HGNC:2240 HGNC:16889	Inhibitors of RPN11	California Institute of Technology	05/18/20	2D 3D TSV
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US10005762	159	80	HGNC:6656	Pyridine derivatives	Astellas Pharma Inc	05/18/20	2D 3D TSV
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US10005739	214	213	HGNC:2730	Quinazolinone and isoquinolinone derivative	Chugai Seiyaku Kabushiki Kaisha	05/18/20	2D 3D TSV
US10005782	218	200	HGNC:1133	Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators	BeiGene, Ltd	05/18/20	2D 3D TSV
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US9999624	8	8	HGNC:933	Combination Alzheimer therapy using anti-N3pGlu Abeta antibodies + a BACE inhibitor	Eli Lilly and Company	05/11/20	2D 3D TSV
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US10323032	332	111	HGNC:8537	P2X7 Modulators	Janssen Pharmaceutica NV	05/11/20	2D 3D TSV
US9999619	794	387		Piperidin-4-yl azetidine derivatives as JAK1 inhibitors	Incyte Holdings Corporation	05/11/20	2D 3D TSV
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US9993465	57	10		2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof	Georgetown University	05/05/20	2D 3D TSV
US9994552	278	138	HGNC:6342	Compositions useful for treating disorders related to kit	BLUEPRINT MEDICINES CORPORATION	05/05/20	2D 3D TSV
US9994546	130	129	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	05/05/20	2D 3D TSV
US9994525	16	16		H3 antagonists containing phenoxypiperidine core structure	Richter Gedeon Nyrt.	05/05/20	2D 3D TSV
US9994547	150	149	HGNC:11584	Heteroarylamide inhibitors of TBK1	Takeda Pharmaceutical Co., Ltd	05/05/20	2D 3D TSV
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US9994590	59	54	HGNC:8772	Substituted [1,2,4]triazolo[1,5-a]pyrazines as phosphodiesterase inhibitors	Sunovion Pharmaceuticals Inc	05/05/20	2D 3D TSV
US9994576	33	33	HGNC:1133	Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors	Principia Biopharma Inc	05/05/20	2D 3D TSV
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US9987274	135	47	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Ogeda SA	04/30/20	2D 3D TSV
US9987255	48	24	HGNC:4849 HGNC:4848	5,5-bicyclic oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	04/25/20	2D 3D TSV
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US9981963	29	29	HGNC:1974	3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors	Janssen Pharmaceutica NV	04/18/20	2D 3D TSV
US9981944	245	124	HGNC:11773	GDF-8 inhibitors	Rigel Pharmaceuticals, Inc	04/18/20	2D 3D TSV
US9981901	75	73	HGNC:3449	IRE-1α inhibitors	FOSUN ORINOVE PHARMATECH, INC.	04/18/20	2D 3D TSV
US9981975	438	146	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as tam inhibitors	Incyte Corporation	04/18/20	2D 3D TSV
US9981909	592	296	HGNC:5301 HGNC:11050 HGNC:5295 HGNC:5294	Serotonin receptor modulators	Janssen Pharmaceutica NV	04/18/20	2D 3D TSV
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US9981950	116	116	HGNC:6251	Triazoles as NR2B receptor inhibitors	JANSSEN PHARMACEUTICALS, INC.	04/18/20	2D 3D TSV
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US10307427	23	18	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences Inc	04/15/20	2D 3D TSV
US10308636	80	80	HGNC:2843	Aromatic heterocyclic compound	Mitsubishi Tanabe Pharma Corporation	04/15/20	2D 3D TSV
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US10308607	3	3	HGNC:4006	Fucosidase inhibitors	HORIZON ORPHAN LLC	04/15/20	2D 3D TSV
US10308628	10	10	HGNC:338	Heterocyclic compounds and methods for their use	Novartis AG	04/15/20	2D 3D TSV
US10308644	271	267		Heterocyclic compounds as immunomodulators	Incyte Corporation	04/15/20	2D 3D TSV
US10308615	344	163		Heterocyclic compounds as inhibitors of Vanin-1 enzyme	Pfizer Inc	04/15/20	2D 3D TSV
US10308663	3	3	HGNC:9636	Inhibitors of PTP4A3 for the treatment of cancer	University of Virginia Patent Foundation	04/15/20	2D 3D TSV
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US10308667	168	167	HGNC:32311	Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors	Boehringer Ingelheim International GmbH	04/15/20	2D 3D TSV
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US10308662	114	28	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Thienopyranones as kinase and epigenetic inhibitors	Signal Rx Pharmaceuticals Inc	04/15/20	2D 3D TSV
US10308652	64	60	HGNC:11892	Tricyclic heterocyclic compounds useful as inhibitors of TNF	Bristol-Myers Squibb Co.	04/15/20	2D 3D TSV
US9975876	63	31	HGNC:4849 HGNC:4848	2-pyridyloxy-3-ester-4-ether orexin receptor antagonists	Merck Sharp & Dohme Corp	04/10/20	2D 3D TSV
US9974785	36	36	HGNC:5301	Aromatic heterocyclic derivatives and pharmaceutical applications thereof	Sunshine Lake Pharma Co., Ltd	04/10/20	2D 3D TSV
US9975862	12	2	HGNC:3023 HGNC:5286	Arylpiperazine derivatives and methods of utilizing same	Reviva Pharmaceuticals Inc	04/10/20	2D 3D TSV
US9975858	10	10	HGNC:10597	Benzimidazole derivatives and use thereof	Purdue Pharma LP	04/10/20	2D 3D TSV
US9975854	3	3	HGNC:8154	Benzomorphan analogs and use thereof	Purdue Pharma LP	04/10/20	2D 3D TSV
US9975902	13	11	HGNC:9257	Compounds for the inhibition of cyclophilins and uses thereof	Merck Patent GmbH	04/10/20	2D 3D TSV
US9975861	11	4	HGNC:933 HGNC:4617	Dual inhibitor compounds for use in the treatment of neurodegenerative disorders and alzheimer''s disease	FONDAZIONE ISTITUTO ITAIANO DI TECNOLOGIA	04/10/20	2D 3D TSV
US9975874	86	44	HGNC:6371 HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	04/10/20	2D 3D TSV
US9975882	212	63	HGNC:1079 HGNC:1133 HGNC:11719 HGNC:12434	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	04/10/20	2D 3D TSV
US9975907	123	80	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Holdings Corporation	04/10/20	2D 3D TSV
US9969723	53	50	HGNC:4498	3-(4-(benzyloxy)phenyl)hex-4-ynoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient	HYUNDAI PHARM CO., LTD	04/06/20	2D 3D TSV
US9969687	122	122	HGNC:1610	Compounds useful as CCR9 modulators	Norgine B.V.	04/06/20	2D 3D TSV
US9969724	53	53	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	04/06/20	2D 3D TSV
US9969749	169	166	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	04/06/20	2D 3D TSV
US9969726	724	190		Metabotropic glutamate receptor negative allosteric modulators (NAMS) and uses thereof	Sanford-Burnham Medical Research Institute	04/06/20	2D 3D TSV
US9969738	28	6	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders	Ogeda SA	04/06/20	2D 3D TSV
US9969700	8	8	HGNC:8535	P2X4 receptor antagonist	Nippon Chemiphar Co., Ltd	04/06/20	2D 3D TSV
US9968610	15	10	HGNC:6251 HGNC:2625	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	04/06/20	2D 3D TSV
US9969686	9	9	HGNC:348	Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them	Wisconsin Alumni Research Foundation	04/06/20	2D 3D TSV
US9969743	260	130	HGNC:3023 HGNC:3024	Urea and amide derivatives of aminoalkylpiperazines and use thereof	Southern Research Institute	04/06/20	2D 3D TSV
US9963460	3	1	HGNC:8153 HGNC:8154 HGNC:8156	Morphinan derivative	University of Tsukuba	03/30/20	2D 3D TSV
US9963444	117	117	HGNC:736	N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof	Northeastern University	03/30/20	2D 3D TSV
US9963434	220	220		N-arylmethyl sulfonamide negative modulators of NR2A	Luc Therapeutics, Inc.	03/30/20	2D 3D TSV
US9963446	26	26		Oxepan-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	Genentech Inc	03/30/20	2D 3D TSV
US9963456	40	40	HGNC:1373	Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	03/30/20	2D 3D TSV
US9962388	45	45	HGNC:15631	Pyrrolopyrimidine compounds used as TLR7 agonist	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	03/30/20	2D 3D TSV
US9963443	13	13		Radiolabeled compounds	Takeda Pharmaceutical Co., Ltd	03/30/20	2D 3D TSV
US9963439	46	18	HGNC:2637 HGNC:20581 HGNC:2603 HGNC:2622 HGNC:2623	Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase	University of Washington Through its Center for Commercialization	03/30/20	2D 3D TSV
US9963453	45	43	HGNC:8157	Substituted pyrazino[1,2-a]indoles as sigma receptor activity modulators	LABORATORIOS DEL DR. ESTEVE S.A.	03/30/20	2D 3D TSV
US9962398	60	15	HGNC:1373 HGNC:1383 HGNC:1371 HGNC:1368	Sulfonamide compounds for inhibition of metastatic tumor growth	Welichem Biotech Inc.	03/30/20	2D 3D TSV
US9962362	18	12	HGNC:3521 HGNC:9642	Use of small molecule inhibitors targeting EYA tyrosine phosphatase	Children''s Hospital Medical Center	03/30/20	2D 3D TSV
US10301320	27	25	HGNC:5154	Compositions and methods of modulating 15-PGDH activity	University of Kentucky Research Foundation	03/26/20	2D 3D TSV
US10301305	252	63		Heteroaromatic derivatives and their use as pharmaceuticals	Mutabilis	03/26/20	2D 3D TSV
US10301323	183	61	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors	BioMarin Pharmaceutical Inc	03/26/20	2D 3D TSV
US10301291	31	31	HGNC:6872	Imidazole derivative having JNK inhibitory activity and use thereof	SAMJIN PHARMACEUTICAL CO., LTD.	03/26/20	2D 3D TSV
US10301317	373	365	HGNC:6871	Inhibitors of ERK and methods of use	Kura Oncology Inc	03/26/20	2D 3D TSV
US10301288	61	15	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Topivert Pharma Limited	03/26/20	2D 3D TSV
US10301336	33	33	HGNC:2771	Phosphonate compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	03/26/20	2D 3D TSV
US10301286	79	33	HGNC:6932 HGNC:6929 HGNC:6931	Piperazine derivative	Astellas Pharma Inc	03/26/20	2D 3D TSV
US10301306	185	180	HGNC:10021	Substituted dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones as RIPK3 inhibitors	Bristol-Myers Squibb Co.	03/26/20	2D 3D TSV
US10301297	63	62	HGNC:1133	Substituted nicotinimide inhibitors of BTK and their preparation and use in the treatment of cancer, inflammation and autoimmune disease	Guangzhou Innocare Pharma Tech Co., Ltd.	03/26/20	2D 3D TSV
US10301284	141	139	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	03/26/20	2D 3D TSV
US10301278	58	54	HGNC:9644	1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2	Novartis AG	03/25/20	2D 3D TSV
US10300056	14	14	HGNC:9843	CGRP receptor antagonists	Heptares Therapeutics Limited	03/25/20	2D 3D TSV
US10301272	844	306		Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ]	Phenex Pharmaceuticals AG	03/25/20	2D 3D TSV
US10301280	257	153	HGNC:6342	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	03/25/20	2D 3D TSV
US10300051	61	61	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/25/20	2D 3D TSV
US10301269	41	41	HGNC:3827	Imidazole derivatives as formyl peptide receptor modulators	Allergan Inc	03/25/20	2D 3D TSV
US10300066	119	118	HGNC:1133	Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors	Zhejiang DTRM Biopharma Co. Ltd	03/25/20	2D 3D TSV
US10300067	53	53	HGNC:644	Tetrahydropyridopyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	03/25/20	2D 3D TSV
US10301253	203	87	HGNC:29079	Therapeutic compounds and uses thereof	Genentech Inc	03/25/20	2D 3D TSV
US10300048	73	53	HGNC:3553	Thiazolidinones as cellular anandamide uptake inhibitors and their use in the treatment of psychiatric or neurological disorders and inflammation, in particular neuroinflammation	UNIVERSITAT BERN	03/25/20	2D 3D TSV
US10300060	43	43	HGNC:8031	Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	03/25/20	2D 3D TSV
US10300058	50	18	HGNC:3236	Tyrosine kinase inhibitor and uses thereof	Xuanzhu Pharma Co., Ltd	03/25/20	2D 3D TSV
US10300074	114	40	HGNC:13702	Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy	Sanford Burnham Prebys Medical Discovery Institute	03/25/20	2D 3D TSV
US9957268	196	88		1H-pyrrolo[2,3,c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	03/23/20	2D 3D TSV
US9956214	208	103		5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum	University of Washington Through its Center for Commercialization	03/23/20	2D 3D TSV
US9957261	118	59		6-amino-5,6,7,8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives	Hoffman-La Roche Inc	03/23/20	2D 3D TSV
US9957235	248	139		Benzimidazol-2-amines as mIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	03/23/20	2D 3D TSV
US9957263	371	184	HGNC:13575	Bromodomain inhibitors	AbbVie Inc	03/23/20	2D 3D TSV
US9957276	44	44	HGNC:1771	CDK inhibitors	GI Therapeutics, Inc.	03/23/20	2D 3D TSV
US9956208	4	4	HGNC:1133	Compounds for the treatment of cancer and inflammatory diseases	TBA	03/23/20	2D 3D TSV
US9957264	938	423	HGNC:6190 HGNC:6192	Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors	Merck Sharp & Dohme Corp	03/23/20	2D 3D TSV
US9957265	226	75	HGNC:6190 HGNC:6192	N-(2-cyano heterocyclyl) pyrazolo pyridones as janus kinase inhibitors	Merck Sharp & Dohme Corp	03/23/20	2D 3D TSV
US9956192	42	21	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	03/23/20	2D 3D TSV
US9951056	63	61	HGNC:1133	Substituted nicotinamide inhibitors of BTK and their preparation and use in the treatment of cancer, inflammation and autoimmune disease	Beijing Innocare Pharma Tech Co., Ltd.	03/18/20	2D 3D TSV
US9951063	147	147	HGNC:4540	8-(piperazin-1-yl)-1,2,3,4-tetrahydro-isoquinoline derivatives	IDORSIA PHARMACEUTICALS Ltd	03/16/20	2D 3D TSV
US9951077	118	116	HGNC:1133	Aminopyridazinone compounds as protein kinase inhibitors	Jiangsu Hengrui Medicine Co., Ltd.	03/16/20	2D 3D TSV
US9951027	390	346		Benzimidazol-2-amines as MIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	03/16/20	2D 3D TSV
US9951071	443	219	HGNC:6371 HGNC:3529	Dihydropyridone P1 as factor XIa inhibitors	Bristol-Myers Squibb Co.	03/16/20	2D 3D TSV
US9951026	13	13	HGNC:3357	Heterocyclic vinyl autotaxin inhibitor compounds	PharmAkea Inc	03/16/20	2D 3D TSV
US9951086	310	305	HGNC:17967	Indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments	Bayer Pharma Aktiengesellschaft	03/16/20	2D 3D TSV
US9949975	25	25	HGNC:933	Inhibitors of beta-secretase	Vitae Pharmaceuticals Inc	03/16/20	2D 3D TSV
US9951048	488	236	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	03/16/20	2D 3D TSV
US9951014	113	35	HGNC:7872 HGNC:7873	Mammalian and bacterial nitric oxide synthase inhibitors	Northwestern University	03/16/20	2D 3D TSV
US9949951	29	28	HGNC:6059	Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors	iTeos Therapeutics	03/16/20	2D 3D TSV
US9951035	6	3	HGNC:7175 HGNC:7176	Selective matrix metalloproteinase inhibitors	University of Notre Dame du Lac	03/16/20	2D 3D TSV
US9951029	63	63	HGNC:3765	Styryl quinazoline derivatives as pharmaceutically active agents	Vichem Chemie Kutató	03/16/20	2D 3D TSV
US9951033	23	23		Tertiary amines for use in the treatment of cardiac disorders	UNIVERSITETET I OSLO	03/16/20	2D 3D TSV
US9944601	159	43	HGNC:6833 HGNC:6834 HGNC:29079	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	03/12/20	2D 3D TSV
US9944646	114	109	HGNC:8977	Bicyclic azaheterocyclobenzylamines as PI3K inhibitors	Incyte Holdings Corporation	03/12/20	2D 3D TSV
US9944606	9	5	HGNC:2160 HGNC:2159	Cannabinoid receptor modulators	Arena Pharmaceuticals Inc	03/12/20	2D 3D TSV
US9944643	8	8	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	03/12/20	2D 3D TSV
US9944647	138	138	HGNC:29079	Heterocyclic compounds as LSD1 inhibitors	Incyte Corporation	03/12/20	2D 3D TSV
US9944645	205	205	HGNC:7029	Imidazotriazines and imidazopyrimidines as kinase inhibitors	Incyte Corporation	03/12/20	2D 3D TSV
US9944618	940	167	HGNC:6251 HGNC:11050 HGNC:2637 HGNC:2625 HGNC:11048 HGNC:11049	Inhibiting neurotransmitter reuptake	Mayo Foundation	03/12/20	2D 3D TSV
US9943516	19	17	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	03/12/20	2D 3D TSV
USRE46792	103	103	HGNC:8783	Oxazole compound and pharmaceutical composition	Otsuka Pharmaceutical Co., Ltd	03/12/20	2D 3D TSV
US9944624	126	61	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics SA	03/12/20	2D 3D TSV
US10294221	63	57		1, 3, 4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	03/10/20	2D 3D TSV
US10294230	48	11	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	03/10/20	2D 3D TSV
US10294218	165	150	HGNC:1780	4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity	VIROSTATICS SRL	03/10/20	2D 3D TSV
US10294227	332	21	HGNC:11283 HGNC:12841 HGNC:9617 HGNC:8803 HGNC:4840 HGNC:6735 HGNC:3697 HGNC:4037 HGNC:1057 HGNC:76 HGNC:6342 HGNC:3955 HGNC:3942 HGNC:9967 HGNC:6524	Compounds	UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH	03/10/20	2D 3D TSV
US10292975	2	2		Compounds as rearranged during transfection (RET) inhibitors	GlaxoSmithKline	03/10/20	2D 3D TSV
US10294217	35	27	HGNC:1950	Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators	Suven Life Sciences Limited	03/10/20	2D 3D TSV
US10294229	444	398	HGNC:17967	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Co.	03/10/20	2D 3D TSV
US10294212	277	273	HGNC:27269 HGNC:6059	Inhibitors of the kynurenine pathway	CURADEV PHARMA, PVT. LTD.	03/10/20	2D 3D TSV
US10292981	53	47	HGNC:6001	Oxazoline and isoxazoline derivatives as CRAC modulators	LUPIN LIMITED	03/10/20	2D 3D TSV
US10294259	6	3	HGNC:11037 HGNC:11036	Phenyl c-glucoside derivative containing deoxyglucose structure, preparation method and use thereof	Tianjin Institute of Pharmaceutical Research	03/10/20	2D 3D TSV
US10294214	80	80	HGNC:6932	Positive allosteric modulators of human melanocortin-4 receptor	Vanderbilt University	03/10/20	2D 3D TSV
US10294223	197	129	HGNC:3689 HGNC:3688	Quinolone derivatives as fibroblast growth factor receptor inhibitors	Principia Biopharma Inc	03/10/20	2D 3D TSV
US10294226	60	15	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	03/10/20	2D 3D TSV
US10294246	271	135	HGNC:9542 HGNC:9545	Substituted boronic acids and boronate esters as immunoproteasome inhibitors	Merck Patent GmbH	03/10/20	2D 3D TSV
US10292985	72	36	HGNC:11773	TGF beta receptor antagonists	Bristol-Myers Squibb Co.	03/10/20	2D 3D TSV
US9938265	43	33		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	03/02/20	2D 3D TSV
US9938276	164	81	HGNC:4849 HGNC:4848	6,5-bicyclic octahydropyrrolopyridine orexin receptor antagonists	Merck Sharp & Dohme Corp	03/02/20	2D 3D TSV
US9938268	34	34	HGNC:11393	C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof	Merck Patent GmbH	03/02/20	2D 3D TSV
US9938222	129	116	HGNC:19061	Cyclopropanecarboxylic acid GPR120 modulators	Bristol-Myers Squibb Co.	03/02/20	2D 3D TSV
US9938267	694	668		Heterocyclic inhibitors of glutaminase	Calithera Biosciences Inc	03/02/20	2D 3D TSV
US9938272	109	34	HGNC:9475 HGNC:3528 HGNC:3535	Hydrazine compound as blood coagulation factor Xa inhibitor	North China Pharmaceutical Company., Ltd.	03/02/20	2D 3D TSV
US9938274	44	22	HGNC:6307 HGNC:7029	Naphthyridine compounds, medical combinations and use thereof	NANJING NATINEFY PHARMATECH CO., LTD.	03/02/20	2D 3D TSV
US9938257	57	25	HGNC:6190 HGNC:6192 HGNC:11393 HGNC:11390 HGNC:3765	Substituted heteroaryl compounds and methods of use	CALITOR SCIENCES, LLC	03/02/20	2D 3D TSV
US9938289	9	9		Therapeutic pyrazolyl thienopyridines	FBM THERAPEUTICS, LLC	03/02/20	2D 3D TSV
US9938290	52	13	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors	Karus Therapeutics Limited	03/02/20	2D 3D TSV
US10287286	262	260	HGNC:14660	Compounds	Takeda Pharmaceutical Co., Ltd	02/29/20	2D 3D TSV
US9931340	68	66	HGNC:2671	Pyridazinone compounds and their use as DAAO inhibitors	Takeda Pharmaceutical Co., Ltd	02/29/20	2D 3D TSV
US10285983	70	70		3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10285982	66	66		3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10287274	43	43	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	02/27/20	2D 3D TSV
US10287270	3	3	HGNC:550	Amino pyrimidine SSAO inhibitors	Eli Lilly and Company	02/27/20	2D 3D TSV
US10287301	719	698	HGNC:2771	Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders	Achillion Pharmaceuticals Inc	02/27/20	2D 3D TSV
US10287293	45	22		Bicyclic heterocyclic compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287292	184	129	HGNC:23692	CXCR7 antagonists	ChemoCentryx, Inc.	02/27/20	2D 3D TSV
US10287258	37	37	HGNC:2528	Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors	AstraZeneca AB	02/27/20	2D 3D TSV
US10287278	40	14	HGNC:6026 HGNC:6027	Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies	Galderma Research & Development	02/27/20	2D 3D TSV
US10285988	30	30	HGNC:15983	Compounds for treatment of fibrosis diseases	CUREGENIX, INC.	02/27/20	2D 3D TSV
US10287300	130	64	HGNC:28426	Heterocyclic derivatives as modulators of kinase activity	Merck Patent GmbH	02/27/20	2D 3D TSV
US10287268	8	4	HGNC:4840 HGNC:1133	Imidazolyl kinase inhibitors and uses thereof	Dana-Farber Cancer Institute Inc	02/27/20	2D 3D TSV
US10287279	42	39	HGNC:433	Inhibitors of human 12/15-lipoxygenase	THE CHILDREN'S HOSPITAL CORPORATION	02/27/20	2D 3D TSV
US10287267	951	304	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10287250	110	35	HGNC:8156	Morphan and morphinan analogues, and methods of use	ALKERMES PHARMA IRELAND LIMITED	02/27/20	2D 3D TSV
US10285989	371	197		Pyrimidinone amide compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287272	149	126		Substituted indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287305	266	261	HGNC:4849	Substituted piperidine compound and use thereof	Takeda Pharmaceutical Co., Ltd	02/27/20	2D 3D TSV
US10287253	52	51	HGNC:15631	Substituted pyrimidines containing acidic groups as TLR7 modulators	APROS THERAPEUTICS, INC.	02/27/20	2D 3D TSV
US10287295	605	303	HGNC:11773	TGF-β inhibitors	Rigel Pharmaceuticals, Inc	02/27/20	2D 3D TSV
US10280166	126	125		2-(1H-indazol-3-yl)-3H-imidazo[4,5-B]pyridine and therapeutic uses thereof	Samumed, LLC	02/24/20	2D 3D TSV
US9932329	28	14	HGNC:6171 HGNC:12434	Benzimidazole derivatives as RLK and ITK inhibitors	Principia Biopharma Inc	02/24/20	2D 3D TSV
US9932325	215	166		Compounds, compositions, and methods	Denali Therapeutics Inc.	02/24/20	2D 3D TSV
US9932332	2	2	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences Inc	02/24/20	2D 3D TSV
US10280171	183	98	HGNC:3255	Heterocyclic inhibitors of PTPN11	The University of Texas System	02/24/20	2D 3D TSV
US10280184	71	69	HGNC:1133	Heterocyclic kinase inhibitors	AbbVie Inc	02/24/20	2D 3D TSV
US9932350	108	101	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	02/24/20	2D 3D TSV
US10280167	39	39		Purine derivatives for the treatment of viral infections	Janssen Ireland	02/24/20	2D 3D TSV
US9932327	10	5	HGNC:1780 HGNC:1771	Rohitukine analogs as cyclin-dependent kinase inhibitors and a process for the preparation thereof	The Council of Scientific & Industrial Research	02/24/20	2D 3D TSV
US9931338	7	7	HGNC:11491	Syk inhibitors	Gilead Sciences Inc	02/24/20	2D 3D TSV
US9932341	125	112	HGNC:8977	Use of pyrazolopyrimidine derivatives for the treatment of PI3K-delta related disorders	Incyte Corporation	02/24/20	2D 3D TSV
US10278968	15	15		Combination therapy with glutaminase inhibitors	Calithera Biosciences Inc	02/21/20	2D 3D TSV
US10278929	41	36	HGNC:12405	Identification of stabilizers of multimeric proteins	The Board of Trustees of the Leland Stanford Junior University	02/21/20	2D 3D TSV
US10280160	31	26	HGNC:1884	Phthalazinone compounds and methods for the treatment of cystic fibrosis	Flatley Discovery Lab LLC	02/21/20	2D 3D TSV
US10280164	16	16	HGNC:6863	Pyrazolopyridone compounds and uses thereof	Incyte Corporation	02/21/20	2D 3D TSV
US10280144	213	213		Pyridazine derivatives as RORc modulators	Genentech Inc	02/21/20	2D 3D TSV
US10280165	40	40		Pyridopyrimidinones and methods of use thereof	Genentech Inc	02/21/20	2D 3D TSV
US10280150	297	183		Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors	FORMA TM2, INC.	02/21/20	2D 3D TSV
US10280174	3	2	HGNC:1133 HGNC:3236	Salt of fused pyrimidine compound and crystal thereof	Taiho Pharmaceutical Co., Ltd	02/21/20	2D 3D TSV
US10278975	186	172	HGNC:6871	Serine/threonine kinase inhibitors	Genentech Inc	02/21/20	2D 3D TSV
US10280149	220	219	HGNC:13610	Therapeutic compounds and uses thereof	Genentech Inc	02/21/20	2D 3D TSV
US10278962	24	11	HGNC:11177 HGNC:11178	Tricyclic analogues, preparation method and uses thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	02/21/20	2D 3D TSV
US10273234	26	26	HGNC:3357	Compounds that are S1P modulating agents and/or ATX modulating agents	BIOGEN MA INC.	02/20/20	2D 3D TSV
US10273222	604	163	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	CELGENE QUANTSCEL RESEARCH, INC.	02/20/20	2D 3D TSV
US10272074	477	475	HGNC:7978	Inhibitors of glucocorticoid receptor translocation	Sanford Burnham Prebys Medical Discovery Institute	02/20/20	2D 3D TSV
US10273211	24	5	HGNC:3763 HGNC:6307 HGNC:11390 HGNC:3767 HGNC:7029 HGNC:9967 HGNC:3765	Metabolites of N-{4-([6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide	Exelixis Inc	02/20/20	2D 3D TSV
US10272079	361	180	HGNC:11073	NHE3-binding compounds and methods for inhibiting phosphate transport	ARDELYX, INC.	02/20/20	2D 3D TSV
US10272095	87	83	HGNC:2874	NRF2 regulators	GlaxoSmithKline	02/20/20	2D 3D TSV
US10272077	14	14		Piperidinone carboxamide azaindane CGRP receptor antagonists	Merck Sharp & Dohme Corp	02/20/20	2D 3D TSV
US10272087	50	8	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pteridines as FGFR inhibitors	Astex Therapeutics Ltd	02/20/20	2D 3D TSV
US10273225	22	21	HGNC:4515	Pyrazines as modulators of GPR6	Takeda Pharmaceutical Co., Ltd	02/20/20	2D 3D TSV
US10273223	391	389	HGNC:3527	Substituted 6,5-fused bicyclic heteroaryl compounds	Epizyme Inc	02/20/20	2D 3D TSV
US10273244	348	173	HGNC:3023 HGNC:3024	Substituted hexahydropyrrolo[3,4-b]pyrroles and hexahydrocyclopenta[c]pyrroles as dopamine receptor modulators	Indivior UK Limited	02/20/20	2D 3D TSV
US10273230	16	15	HGNC:19061	Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof	Piramal Enterprises Limited	02/20/20	2D 3D TSV
US10273214	78	39	HGNC:4588 HGNC:4587 HGNC:4586	Subunit selective NMDA receptor potentiators for the treatment of neurological conditions	Emory University	02/20/20	2D 3D TSV
US10273259	881	804		Tricyclic sulfones as RORγ modulators	Bristol-Myers Squibb Co.	02/20/20	2D 3D TSV
US9890168	32	15	HGNC:3236	2,4-disubstituted 7H-pyrrolo[2,3-d]pyrimidine derivative, preparation method and medicinal use thereof	Shanghai Haiyan Pharmaceutical Technology Co., Ltd.	02/16/20	2D 3D TSV
US9890171	200	130	HGNC:2592	Aldosterone synthase inhibitors	Boehringer Ingelheim International GmbH	02/16/20	2D 3D TSV
US9890124	46	23	HGNC:15631 HGNC:15632	Benzazepine sulfonamide compounds	Hoffmann-La Roche Inc	02/16/20	2D 3D TSV
US9890162	156	52	HGNC:19310 HGNC:8987	Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors	Incyte Corporation	02/16/20	2D 3D TSV
US9890156	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	02/16/20	2D 3D TSV
US9890160	3	3	HGNC:550	Compounds I	Proximagen Limited	02/16/20	2D 3D TSV
US9890166	638	168	HGNC:13575 HGNC:1103 HGNC:2348 HGNC:1104	Imidazopyrrolidine derivatives and their use in the treatment of disease	Novartis AG	02/16/20	2D 3D TSV
US9890185	468	169	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Urea derivatives useful as kinase inhibitors	Respivert Limited	02/16/20	2D 3D TSV
US9926281	1937	451	HGNC:7160 HGNC:195 HGNC:7155 HGNC:7166 HGNC:7159 HGNC:221	5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis	Galapagos NV	02/10/20	2D 3D TSV
US9926301	28	13		Bipyrazole derivatives as JAK inhibitors	Incyte Corporation	02/10/20	2D 3D TSV
US9926306	34	33		Inhibition of MCL-1 and/or BFL-1/A1	Dana-Farber Cancer Institute Inc	02/10/20	2D 3D TSV
US9926330	55	53	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	02/10/20	2D 3D TSV
US9926299	34	34	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Centaurus BioPharma Co., Ltd	02/10/20	2D 3D TSV
US9926282	826	401	HGNC:10251 HGNC:10252	Phthalazinones and isoquinolinones as rock inhibitors	Bristol-Myers Squibb Co.	02/10/20	2D 3D TSV
US9926318	58	53	HGNC:3357	Tetracyclic autotaxin inhibitors	PharmAkea Inc	02/10/20	2D 3D TSV
USRE47351	11	11		2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists	Gilead Sciences Inc	02/07/20	2D 3D TSV
US10266528	23	22	HGNC:1133	2-oxo-imidazopyridines as reversible BTK inhibitors and uses thereof	Merck Patent GmbH	02/07/20	2D 3D TSV
US10266537	116	27	HGNC:6613 HGNC:3763 HGNC:11724 HGNC:6735 HGNC:4037 HGNC:3386 HGNC:5960 HGNC:6859 HGNC:9829 HGNC:3689 HGNC:6873 HGNC:7027 HGNC:3767 HGNC:2730 HGNC:7029 HGNC:3688 HGNC:2731 HGNC:6192 HGNC:8031 HGNC:12841 HGNC:9617 HGNC:8803 HGNC:4840 HGNC:3430 HGNC:6307 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:3395 HGNC:77 HGNC:1097 HGNC:76 HGNC:3393 HGNC:3955 HGNC:3236 HGNC:2444 HGNC:1974 HGNC:6524	3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereof	St. Chuan University	02/07/20	2D 3D TSV
US10265310	158	71	HGNC:3827 HGNC:3826	6-membered cyclic amines or lactames substituted with urea and phenyl	GRÜNENTHAL GMBH	02/07/20	2D 3D TSV
US10266550	64	26	HGNC:11986 HGNC:11989	Bacterial topoisomerase I inhibitors with antibacterial activity	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES	02/07/20	2D 3D TSV
US10259818	114	109	HGNC:8977	Bicyclic azaheterocyclobenzylamines as PI3K inhibitors	Incyte Corporation	02/07/20	2D 3D TSV
US10266560	65	64	HGNC:7967	Bile acid analogs as FXR/TGR5 agonists and methods of use thereof	Enanta Pharmaceuticals Inc	02/07/20	2D 3D TSV
US10259776	16	13	HGNC:4685	Branched 3-phenylpropionic acid derivatives and their use	Bayer Intellectual Property GmbH	02/07/20	2D 3D TSV
US10266513	190	134	HGNC:1133 HGNC:3236	Bruton's tyrosine kinase inhibitors	Pfizer Inc	02/07/20	2D 3D TSV
US10266491	200	168	HGNC:1133	Carbazole derivatives	Bristol-Myers Squibb Co.	02/07/20	2D 3D TSV
US10266496	160	118	HGNC:12805 HGNC:17989	Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof	Sunshine Lake Pharma Co., Ltd	02/07/20	2D 3D TSV
US10259816	26	26	HGNC:427	Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	02/07/20	2D 3D TSV
US10266542	19	18	HGNC:3527	EZH2 inhibitors	Mirati Therapeutics Inc	02/07/20	2D 3D TSV
US10266535	56	29	HGNC:1133 HGNC:3765	Inhibitor of FLT3 kinase and use thereof	HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES	02/07/20	2D 3D TSV
US10259786	8	4	HGNC:3023	Psychotropic agents and uses thereof	LB PHARMACEUTICALS INC.	02/07/20	2D 3D TSV
US10266526	956	932	HGNC:20982	Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer	Epizyme Inc	02/07/20	2D 3D TSV
US10266548	211	187	HGNC:1148	Substituted benzylindazoles for use as Bub1 kinase inhibitors in the treatment of hyperproliferative diseases	Bayer Intellectual Property GmbH	02/07/20	2D 3D TSV
US10259811	517	258	HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	02/07/20	2D 3D TSV
US10266515	202	144	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	02/07/20	2D 3D TSV
US10265307	324	106	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors	Incyte Corporation	02/07/20	2D 3D TSV
US10266493	71	70	HGNC:17989	Thioacetate compounds, compositions and methods of use	Ardea Biosciences, Inc.	02/07/20	2D 3D TSV
US10266549	345	343	HGNC:12558	ULK1 inhibitors and methods using same	Salk Institute	02/07/20	2D 3D TSV
US9918985	181	155		Compounds and their use as BACE inhibitors	AstraZeneca AB	02/04/20	2D 3D TSV
US9920047	375	109	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	02/04/20	2D 3D TSV
US9920032	510	168	HGNC:19310 HGNC:8987	Heterocyclic compounds useful as pim kinase inhibitors	Incyte Corporation	02/04/20	2D 3D TSV
US9920031	261	218	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Co.	02/04/20	2D 3D TSV
US9920038	62	30	HGNC:4849	Methyl oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	02/04/20	2D 3D TSV
US9920054	104	104		Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof	Pfizer Inc	02/04/20	2D 3D TSV
US9920053	130	35	HGNC:6251 HGNC:11050 HGNC:11048 HGNC:11049	N-(hetero)aryl-substituted heteroyclic derivatives useful for the treatment of diseases or conditions related to the central nervous system	CHRONOS THERAPEUTICS LIMITED	02/04/20	2D 3D TSV
US9920060	80	79	HGNC:3430	Pyrazolo[3,4-d]pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	02/04/20	2D 3D TSV
US9918974	2	2		Pyridone derivatives as rearranged during transfection (RET) kinase inhibitors	GlaxoSmithKline	02/04/20	2D 3D TSV
US9918969	16	14	HGNC:3529	Substituted oxopyridine derivatives and use thereof as factor XIa/plasma	Bayer Pharma Aktiengesellschaft	02/04/20	2D 3D TSV
US9918990	226	111	HGNC:13575 HGNC:1103	Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors	Incyte Corporation	02/04/20	2D 3D TSV
US9914735	391	78	HGNC:11491 HGNC:11390 HGNC:4617 HGNC:3765	Heteroaryl Syk inhibitors	Boehringer Ingelheim International GmbH	01/30/20	2D 3D TSV
US9914707	30	30	HGNC:6307	Naphthylamide compound, preparation method and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	01/30/20	2D 3D TSV
US9914731	293	156	HGNC:7029	Pyrazolo[1,5-a]pyridine derivatives and methods of their use	IGNYTA, INC.	01/30/20	2D 3D TSV
US9914736	114	113	HGNC:8031	TrKA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	01/30/20	2D 3D TSV
US9914740	420	404	HGNC:10252	Tricyclic pyrido-carboxamide derivatives as rock inhibitors	Bristol-Myers Squibb Co.	01/30/20	2D 3D TSV
US9914721	22	11	HGNC:4849 HGNC:4848	Use of benzimidazole-proline derivatives	IDORSIA PHARMACEUTICALS Ltd	01/30/20	2D 3D TSV
US9908875	45	45	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences Inc	01/27/20	2D 3D TSV
US9908845	68	65	HGNC:12680	Aryl ethers and uses thereof	PELOTON THERAPEUTICS, INC.	01/27/20	2D 3D TSV
US9908886	266	132	HGNC:7110 HGNC:7111	Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof	Agency for Science, Technology and Research	01/27/20	2D 3D TSV
US9908899	143	48	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors	BioMarin Pharmaceutical Inc	01/27/20	2D 3D TSV
US9908865	511	154	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	01/27/20	2D 3D TSV
US9907800	460	198	HGNC:11393 HGNC:11390 HGNC:11397 HGNC:3765	Kinase inhibitors and method of treating cancer	University Health Network	01/27/20	2D 3D TSV
US9908872	19	8	HGNC:1133 HGNC:4195 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute Inc	01/27/20	2D 3D TSV
US9908897	306	84	HGNC:6251 HGNC:11050 HGNC:11048 HGNC:11049	Spirocyclic derivatives	CHRONOS THERAPEUTICS LIMITED	01/27/20	2D 3D TSV
US9908895	196	88	HGNC:6190 HGNC:6192	Tricyclic fused thiophene derivatives as JAK inhibitors	Incyte Corporation	01/27/20	2D 3D TSV
US10246444	134	32	HGNC:3432 HGNC:3430 HGNC:3236	1,2-dithiolane and dithiol compounds useful in treating mutant EGFR-mediated diseases and conditions	SABILA BIOSCIENCES LLC	01/21/20	2D 3D TSV
US10246442	135	135		4-Aminoquinazolin compounds as prolyl hydroxylase inhibitors	Janssen Pharmaceutica NV	01/21/20	2D 3D TSV
US10253018	41	41	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals Inc	01/21/20	2D 3D TSV
US9896418	68	65	HGNC:12680	Aryl ethers and uses thereof	PELOTON THERAPEUTICS, INC.	01/21/20	2D 3D TSV
US9903855	20	5	HGNC:5960 HGNC:11584 HGNC:14552 HGNC:1974	Assays for screening for or identifying an agent or molecule that can block or inhibit AVB3 integrin from forming a complex with KRAS	The Regents of the University of California	01/21/20	2D 3D TSV
US9896444	175	101		Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1	Novartis AG	01/21/20	2D 3D TSV
US10246453	1146	330	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc	01/21/20	2D 3D TSV
US9902722	237	234	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Co.	01/21/20	2D 3D TSV
US10251892	856	186	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	01/21/20	2D 3D TSV
US10246462	92	88	HGNC:1605	Chemokine receptor modulators and uses thereof	FLX BIO, INC.	01/21/20	2D 3D TSV
US9896458	251	243		Compounds, compositions and methods	Denali Therapeutics Inc.	01/21/20	2D 3D TSV
US10253017	22	9	HGNC:7856 HGNC:263 HGNC:264	Derivatives of 2-aminopyridine as adenosine A2B receptor antagonists and ligands of the melatonin MT3 receptors	Palobiofarma, S.L.	01/21/20	2D 3D TSV
US10246466	54	18	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:427 HGNC:10261	Diaryl macrocycles as modulators of protein kinases	TP Therapeutics, Inc.	01/21/20	2D 3D TSV
US9895376	116	57		Fused tricyclic compounds as Raf kinase inhibitors	BeiGene, Ltd	01/21/20	2D 3D TSV
US9896436	329	106	HGNC:29012 HGNC:13606 HGNC:17071 HGNC:18039 HGNC:20672 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	01/21/20	2D 3D TSV
US10246456	686	509	HGNC:17967	IRAK4 inhibiting agents	BIOGEN MA INC.	01/21/20	2D 3D TSV
US10253004	54	53	HGNC:4498	Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	01/21/20	2D 3D TSV
US10246457	56	28	HGNC:1133	Indazole and azaindazole Btk inhibitors	Merck Sharp & Dohme Corp	01/21/20	2D 3D TSV
US10252984	51	51	HGNC:4545	Inhibiting G protein coupled receptor 6 kinase polypeptides	Mayo Foundation	01/21/20	2D 3D TSV
US9902719	31	31	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	01/21/20	2D 3D TSV
US9902741	68	46	HGNC:8031	Macrocyclic compounds as TRK kinase inhibitors	Array BioPharma Inc	01/21/20	2D 3D TSV
US10251893	230	227	HGNC:15983	N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as Wnt signaling modulators	Novartis AG	01/21/20	2D 3D TSV
US9896435	31	31	HGNC:8031	N-pyrrolidinyl,N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors	Array BioPharma Inc	01/21/20	2D 3D TSV
US9902709	13	13	HGNC:6307	Polysubstituted pyridine compound, preparation method, use and pharmaceutical composition	PEKING UNIVERSITY FOUNDER GROUP CO., LTD.	01/21/20	2D 3D TSV
US10253015	169	85		Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors	FORMA TM2, INC.	01/21/20	2D 3D TSV
US9902726	5	4	HGNC:8154 HGNC:8156	Pyridone-sulfone morphinan analogs as opioid receptor ligands	Purdue Pharma LP	01/21/20	2D 3D TSV
US9902714	35	7	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Quinoxaline derivatives useful as FGFR kinase modulators	Astex Therapeutics Ltd	01/21/20	2D 3D TSV
US10246467	67	57		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors	Boehringer Ingelheim International GmbH	01/21/20	2D 3D TSV
US9902710	169	168	HGNC:8772	Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)	Exonhit Therapeutics, SA	01/21/20	2D 3D TSV
US9896452	703	365	HGNC:4849 HGNC:4848	Substituted prolines/piperidines as orexin receptor antagonists	EOLAS THERAPEUTICS, INC.	01/21/20	2D 3D TSV
US10251889	530	232	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:12440	Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharm Inc.	01/21/20	2D 3D TSV
US10253019	1854	609	HGNC:6192 HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	01/21/20	2D 3D TSV
US9896447	46	46	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	01/21/20	2D 3D TSV
US10238658	120	32	HGNC:4840 HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as p38 MAP kinase inhibitors	Respivert Limited	12/30/19	2D 3D TSV
US10239843	681	620	HGNC:8605 HGNC:270	2,4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG	Cancer Research Technology Limited	12/30/19	2D 3D TSV
US10246425	16	16	HGNC:10593	3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds	Parion Sciences Inc	12/30/19	2D 3D TSV
US10246432	25	22	HGNC:4597	4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators	Heptares Therapeutics Limited	12/30/19	2D 3D TSV
US10239883	665	132	HGNC:6735 HGNC:4037 HGNC:1133 HGNC:11283 HGNC:6524	4-imidazopyridazin-1-yl-benzamides as BTK inhibitors	Merck Sharp & Dohme B.V.	12/30/19	2D 3D TSV
US10239868	43	43	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	12/30/19	2D 3D TSV
US10239840	22	22		Benzoazepine derivatives	ViiV HEALTHCARE UK LIMITED	12/30/19	2D 3D TSV
US10238638	48	48		Benzothiazole and benzothiophene compounds	Universite de Montreal	12/30/19	2D 3D TSV
US10245267	2564	1057	HGNC:9829	Biaryl amide compounds as kinase inhibitors	Novartis AG	12/30/19	2D 3D TSV
US10238743	98	49	HGNC:934 HGNC:933	C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	TBA	12/30/19	2D 3D TSV
US10239870	462	190	HGNC:3023	Dopamine D3 receptor antagonists	Indivior UK Limited	12/30/19	2D 3D TSV
US10239838	106	53	HGNC:4849 HGNC:4848	Heteroaryl orexin receptor antagonists	Merck Sharp & Dohme Corp	12/30/19	2D 3D TSV
US10246419	13	12	HGNC:7965	Liver X receptor (LXR) modulators	RALEXAR THERAPEUTICS, INC.	12/30/19	2D 3D TSV
US10238633	584	357	HGNC:2528 HGNC:2536	Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C	Boehringer Ingelheim International GmbH	12/30/19	2D 3D TSV
US10239835	142	141		N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[c]pyrrole negative allosteric modulators of NR2B	CADENT THERAPEUTICS, INC.	12/30/19	2D 3D TSV
US10239887	97	75	HGNC:1953	Positive allosteric modulators of the muscarinic acetylcholine receptor M4	Vanderbilt University	12/30/19	2D 3D TSV
US10239881	26	25	HGNC:10020	RIPK2 inhibitors and method of treating cancer with same	University Health Network	12/30/19	2D 3D TSV
US10239882	86	86		Substituted 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine compounds as PDE2 inhibitors	Dart NeuroScience (Cayman) Ltd	12/30/19	2D 3D TSV
US10239869	405	243	HGNC:10593 HGNC:10597	Sulfonamide compounds as voltage-gated sodium channel modulators	LUPIN LIMITED	12/30/19	2D 3D TSV
US10239861	60	58	HGNC:8638	Therapeutic compounds and uses thereof	Genetech, Inc	12/30/19	2D 3D TSV
US10239876	170	169	HGNC:3020	Triaza-spirodecanones as DDR1 inhibitors	Hoffman-La Roche Inc	12/30/19	2D 3D TSV
US10246426	240	240	HGNC:1395	Triazole compounds as T-type calcium channel blockers	IDORSIA PHARMACEUTICALS Ltd	12/30/19	2D 3D TSV
US10245275	158	76		Triterpenoids with HIV maturation inhibitory activity	VIIV HEALTHCARE UK (NO. 4) LIMITED	12/30/19	2D 3D TSV
US10246429	755	248	HGNC:934 HGNC:2529 HGNC:933	Vinyl fluoride cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use	Amgen Inc	12/30/19	2D 3D TSV
US10227299	295	287	HGNC:1148	3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones	Bayer Pharma Aktiengesellschaft	12/27/19	2D 3D TSV
US10233156	57	57	HGNC:85	9-membered fused ring derivative	Shionogi & Co., Ltd	12/27/19	2D 3D TSV
US10233178	24	8	HGNC:6833 HGNC:6834 HGNC:29079	Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use	Oryzon Genomics, S.A.	12/27/19	2D 3D TSV
US10226452	45	45	HGNC:735	Benzoxazolone derivatives as acid ceramidase inhibitors, and their use as medicaments	University of California	12/27/19	2D 3D TSV
US10233188	433	221	HGNC:1771	CDK2/4/6 inhibitors	Pfizer Inc	12/27/19	2D 3D TSV
US10227357	1107	650	HGNC:6342	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	12/27/19	2D 3D TSV
US10231967	323	159	HGNC:620	Compounds and their use as BACE inhibitors	AstraZeneca AB	12/27/19	2D 3D TSV
US10227360	50	49	HGNC:19061	Compounds for use as GPR120 agonists	Piramal Enterprises Limited	12/27/19	2D 3D TSV
US10227329	268	130	HGNC:9967	Compounds useful for treating disorders related to RET	BLUEPRINT MEDICINES CORPORATION	12/27/19	2D 3D TSV
US10227314	13	13	HGNC:2501	Cystathionine-gamma-lyase (CSE) inhibitors	SOVA PHARMACEUTICALS, INC.	12/27/19	2D 3D TSV
US10227373	6	6		Enantiomers of the 1′,6′-isomer of neplanocin A	Auburn University	12/27/19	2D 3D TSV
US10227334	8	8	HGNC:3467	Estrogen receptor modulators and uses thereof	Genentech Inc	12/27/19	2D 3D TSV
US10233187	49	47	HGNC:7967	Fused bicyclic compounds for the treatment of disease	AKARNA THERAPEUTICS, LTD.	12/27/19	2D 3D TSV
US10233189	78	76	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	12/27/19	2D 3D TSV
US10227310	6	6	HGNC:32311	Ghrelin 0-acyl transferase inhibitors	Eli Lilly and Company	12/27/19	2D 3D TSV
US10227312	46	46	HGNC:12524	Glucosylceramide synthase inhibitors for the treatment of diseases	BioMarin Pharmaceutical Inc	12/27/19	2D 3D TSV
US10227342	400	99	HGNC:3236	Heteroaryl compounds for kinase inhibition	ARIAD Pharmaceuticals Inc	12/27/19	2D 3D TSV
US10226449	595	337	HGNC:3594	Heterocyclic modulators of lipid synthesis and combinations thereof	3-V Biosciences, Inc.	12/27/19	2D 3D TSV
US10231957	21	21	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	12/27/19	2D 3D TSV
US10233190	160	157	HGNC:6059	IDO inhibitors	NewLink Genetics Corporation	12/27/19	2D 3D TSV
US10227341	146	145	HGNC:1133	Inhibiting agents for bruton's tyrosine kinase	BIOGEN MA INC.	12/27/19	2D 3D TSV
US10227327	27	11		Inhibitors of metallo-beta-lactamase (MBL) comprising a zinc chelating moiety	Universitetet | Oslo	12/27/19	2D 3D TSV
US10227343	112	109	HGNC:4596	Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	12/27/19	2D 3D TSV
US10233152	161	158	HGNC:29079	LSD1 inhibitors	Mirati Therapeutics Inc	12/27/19	2D 3D TSV
US10227331	1137	369		Metallo-β-lactamase inhibitors	Merck Sharp & Dohme Corp	12/27/19	2D 3D TSV
US10231963	109	39	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	12/27/19	2D 3D TSV
US10227346	104	104		Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use therof	Pfizer Inc	12/27/19	2D 3D TSV
US10227350	167	129	HGNC:8980	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	12/27/19	2D 3D TSV
US10227336	32	16	HGNC:4849 HGNC:4848	Pyrazole orexin receptor antagonists	Merck Sharp & Dohme Corp	12/27/19	2D 3D TSV
US10227295	48	24	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	12/27/19	2D 3D TSV
US10226464	150	75	HGNC:7794	Small molecule NF-κB inhibitors	ImmuneTarget, Inc.	12/27/19	2D 3D TSV
US10233173	647	642		Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators	Janssen Pharmaceutica NV	12/27/19	2D 3D TSV
US10227338	181	136	HGNC:10593 HGNC:10597	Substituted benzenesulfonamides as sodium channel blockers	Daewoong Pharmaceutical Co., Ltd.	12/27/19	2D 3D TSV
US10233160	150	75	HGNC:391 HGNC:10436	Substituted pyrido[3,4-d]pyrimidines and pyrido[4,3-d]pyrimidines as p70S6K inhibitors	Merck Patent GmbH	12/27/19	2D 3D TSV
US10233182	245	243	HGNC:3357	Substituted spirocyclic inhibitors of autotaxin	X-Rx, Inc.	12/27/19	2D 3D TSV
US10227332	8	4	HGNC:2160	T-type calcium channel modulator and uses thereof	UTI LIMITED PARTNERSHIP	12/27/19	2D 3D TSV
US10233177	25	25		TRPV1 vanilloid receptor antagonists with a bicyclic portion	TBA	12/27/19	2D 3D TSV
US10227340	27	26	HGNC:17967	Thiazolyl- or thiadiazolyl-substituted pyridyl compounds useful as kinase inhibitors	Bristol-Myers Squibb Co.	12/27/19	2D 3D TSV
US10227359	58	28	HGNC:13575	Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	12/27/19	2D 3D TSV
US9872852	297	292	HGNC:17635	Compounds useful as immunomodulators	Bristol-Myers Squibb Co.	12/19/19	2D 3D TSV
US9873693	331	307		Methods of treatment using pyridinonyl PDK1 inhibitors	Sunesis Pharmaceuticals Inc	12/19/19	2D 3D TSV
US9873683	43	43	HGNC:8535	P2X4 receptor antagonist	Nippon Chemiphar Co., Ltd	12/19/19	2D 3D TSV
US9873709	1144	774	HGNC:6190 HGNC:6192	Triazolopyridine compounds, compositions and methods of use thereof	Genentech Inc	12/19/19	2D 3D TSV
US9867826	100	47	HGNC:391	Heterocycles as modulators of kinase activity	Merck Patent GmbH	12/12/19	2D 3D TSV
US9868726	123	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	Allergan Inc	12/12/19	2D 3D TSV
US9868720	93	92	HGNC:6851	C-linked heterocycloaklyl substituted pyrimidines and their uses	Genentech Inc	12/10/19	2D 3D TSV
US9868738	102	51	HGNC:934 HGNC:933	Diazine-fused amidines as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	12/10/19	2D 3D TSV
US9868744	23	19	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	12/10/19	2D 3D TSV
US9868729	216	214	HGNC:11491	Inhibitors of protein kinases	Portola Pharmaceuticals Inc	12/10/19	2D 3D TSV
US9867833	197	185	HGNC:6871	Serine/threonine kinase inhibitors	Genentech Inc	12/10/19	2D 3D TSV
US9868748	113	110		Thiazolopyrrolidine inhibitors of ROR- γ	Vitae Pharmaceuticals Inc	12/10/19	2D 3D TSV
US9862688	47	7	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:76 HGNC:12440	Hydrophobically tagged janus kinase inhibitors and uses thereof	Dana-Farber Cancer Institute Inc	12/03/19	2D 3D TSV
US9862730	405	393	HGNC:3540	Imidazothiadiazole derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation	Bristol-Myers Squibb Co.	12/03/19	2D 3D TSV
US9861612	9	7		Indolyl-containing RORγt inhibitors	ORCA PHARMACEUTICALS LIMITED	12/03/19	2D 3D TSV
US9862726	40	20	HGNC:8154 HGNC:8156	Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans	Purdue Pharma LP	12/03/19	2D 3D TSV
US9862679	189	58		Potent and selective inhibitors of monoamine transporters; method of making; and use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH	12/03/19	2D 3D TSV
US9862711	91	13	HGNC:8978 HGNC:8984 HGNC:8975 HGNC:3942 HGNC:8974 HGNC:8977 HGNC:8976	Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors	Novartis AG	12/03/19	2D 3D TSV
US9862721	13	13	HGNC:3357	Tetrahydrocarboline derivative	Ono Pharmaceutical Co., Ltd	12/03/19	2D 3D TSV
US9862707	103	83	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	12/03/19	2D 3D TSV
US9856252	107	106	HGNC:10894	2-(hetero)aryl-benzimidazole and imidazopyridine derivatives as inhibitors of asparagime emethyl transferase	Cancer Therapeutics CRC Pty Ltd	11/21/19	2D 3D TSV
US9855269	345	340	HGNC:6866	Aminoquinazoline and pyridopyrimidine derivatives	Genentech Inc	11/21/19	2D 3D TSV
US9856239	42	38	HGNC:17989	Carboxylic acid compound, method for preparation thereof, and use thereof	InventisBio Shanghai Ltd.	11/21/19	2D 3D TSV
US9856263	41	39	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	11/21/19	2D 3D TSV
US9856220	125	124	HGNC:8772	Inhibitor compounds of phosphodiesterase type 10A	AbbVie Deutschland GmbH & Co. KG	11/21/19	2D 3D TSV
US9856257	68	68	HGNC:16672	Pyrazolonaphthyridinone derivatives as MetAP2 inhibitors (methionine aminopeptidase type-2)	Sanofi	11/21/19	2D 3D TSV
US9856274	42	42	HGNC:8772	Substituted pyrazolo[1,5-a]pyridines as PDE-10 inhibitors	Sunovion Pharmaceuticals Inc	11/21/19	2D 3D TSV
US9856250	58	57	HGNC:1395	Substituted tropane derivatives	Toa Eiyo Ltd	11/21/19	2D 3D TSV
US9855229	11	11		Treatment of respiratory disorders using ROR-gamma inhibitors	GLENMARK PHARMACEUTICALS S.A.	11/21/19	2D 3D TSV
US9849138	10	5		1,4-benzodiazepone-2,5-diones and related compounds with therapeutic properties	The Regents of the University of Michigan	11/14/19	2D 3D TSV
US9850203	128	122	HGNC:3357	Autotaxin inhibitor compounds	PharmAkea Inc	11/14/19	2D 3D TSV
US9850225	378	375	HGNC:17635	Compounds useful as immunomodulators	Bristol-Myers Squibb Co.	11/14/19	2D 3D TSV
US9845313	167	151	HGNC:10597	Cycloalkane derivatives	Daiichi Sankyo Company, Limited	11/14/19	2D 3D TSV
US9850245	24	21	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	11/14/19	2D 3D TSV
US9845310	772	485	HGNC:339	Intermediates for preparing triazole agonists of the APJ receptor	Amgen Inc	11/14/19	2D 3D TSV
US9845308	66	62		Isoindoline inhibitors of ROR-gamma	Vitae Pharmaceuticals Inc	11/14/19	2D 3D TSV
US9844553	19	10	HGNC:2592 HGNC:2591	Pyrazolopyridyl compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	11/14/19	2D 3D TSV
US9844535	28	27	HGNC:6080	SHP2 inhibitors and methods of treating autoimmune and/or glomerulonephritis-associated diseases using SHP2 inhibitors	Indiana University Research and Technology Corporation	11/14/19	2D 3D TSV
US9845333	164	47	HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	TBA	11/14/19	2D 3D TSV
US9850258	152	43	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Co.	11/14/19	2D 3D TSV
US9850277	402	207		Therapeutically active compositions and their methods of use	Agios Pharmaceuticals Inc	11/14/19	2D 3D TSV
US9850257	26	13		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	11/14/19	2D 3D TSV
US9840503	33	10	HGNC:7027 HGNC:12446	Heterocyclic compounds and uses thereof	Incyte Corporation	10/31/19	2D 3D TSV
US9840501	242	121		Morpholin-pyridine derivatives	Hoffmann-La Roche Inc	10/31/19	2D 3D TSV
US9840508	90	18	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-methyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders	OGED SA	10/31/19	2D 3D TSV
US9840498	95	32	HGNC:8978 HGNC:8975 HGNC:8977	Substituted quinazolin-4-one derivatives	Novartis AG	10/31/19	2D 3D TSV
US9834554	41	41	HGNC:1133	BTK inhibitors	Merck Sharp & Dohme Corp	10/28/19	2D 3D TSV
US9834513	249	125	HGNC:6371 HGNC:6357	Benzylamine derivatives	Kalvista Pharmceuticals Limited	10/28/19	2D 3D TSV
US9834543	16	12	HGNC:10597	Indazoles and use thereof	Purdue Pharma LP	10/28/19	2D 3D TSV
US9833448	14	14	HGNC:16709	Piperidinone carboxamide azaindane CGRP receptor antagonists	Merck Sharp & Dohme Corp	10/28/19	2D 3D TSV
US9834548	407	129	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyridazine compounds as JAK inhibitors	Portola Pharmaceuticals Inc	10/28/19	2D 3D TSV
US9834551	220	109	HGNC:6193 HGNC:6171	Substituted pyrrolo[2,3-b]pyrazines and substituted pyrazolo[3,4-b]pyridines as ITK and JAK kinase inhibitors	ARRIEN PHARMACEUTICALS LLC	10/28/19	2D 3D TSV
US9834564	209	209	HGNC:8772	Substituted quinolines as PDE-10 inhibitors	Sunovion Pharmaceuticals Inc	10/28/19	2D 3D TSV
US9833457	26	13	HGNC:8783	Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	10/28/19	2D 3D TSV
US9834565	58	29		Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	10/28/19	2D 3D TSV
US10221182	98	19	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoro-piperidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	10/27/19	2D 3D TSV
US10221172	65	64	HGNC:4596	Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/27/19	2D 3D TSV
US10221173	451	159	HGNC:6251 HGNC:3467	Chemical compounds	AstraZeneca AB	10/27/19	2D 3D TSV
US10221177	261	248	HGNC:497	Inhibiting the transient receptor potential A1 ion channel	Hydra Biosciences Inc	10/27/19	2D 3D TSV
US10221163	1497	492		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp	10/27/19	2D 3D TSV
US10221174	46	22	HGNC:6943 HGNC:990	N-(phenylsulfonyl)benzamides and related compounds as BCL-2 inhibitors	The Regents of the University of Michigan	10/27/19	2D 3D TSV
US10221197	528	147	HGNC:8978 HGNC:8980 HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	10/27/19	2D 3D TSV
US10221178	83	82	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme Corp	10/27/19	2D 3D TSV
US10221195	46	44	HGNC:438	Pyridine compounds	Daiichi Sankyo Company, Limited	10/27/19	2D 3D TSV
USRE47267	31	25	HGNC:6027	Pyridinecarboxamides as CXCR2 modulators	Syntrix Biosystems, Inc.	10/27/19	2D 3D TSV
US10221175	42	42	HGNC:1950	Substituted pyrrolo[3,4-e]indolizines, imidazo[1,2-a]pyrrolo[3,4-e]pyridines, pyrrolo[3,4-e][1,2,4]triazolo[1,5-a]pyridines and pyrrolo[3,4-e][1,2,4]triazolo[4,3-a]pyridines as positive allosteric modulators of muscarinic acetylcholine receptor M1	Vanderbilt University	10/27/19	2D 3D TSV
US9828368	146	64	HGNC:4849	Oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	10/24/19	2D 3D TSV
US9828396	92	92	HGNC:2771	Alkyne compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	10/22/19	2D 3D TSV
US9828348	10	10	HGNC:10597	Benzimidazole derivatives and use thereof	Purdue Pharma LP	10/22/19	2D 3D TSV
US9828339	224	224	HGNC:1952	Biphenyl derivatives and methods for preparing same	DONG-A ST CO., LTD	10/22/19	2D 3D TSV
US9828343	199	93	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	10/22/19	2D 3D TSV
US9828369	167	166	HGNC:16940	Isoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharpe & Dohme Corp.	10/22/19	2D 3D TSV
US9828378	257	69	HGNC:8978 HGNC:8972 HGNC:8975 HGNC:8977	Kinase inhibitors and methods of use	Intellikine LLC	10/22/19	2D 3D TSV
US9828374	94	47		Substituted pyrazino[2,2-a]isoquinoline derivatives	Hoffmann-La Roche Inc	10/22/19	2D 3D TSV
US9828381	88	88		Substituted pyrazolopyrimidines and method of use	AbbVie Deutschland GmbH & Co. KG	10/22/19	2D 3D TSV
US10214477	210	56	HGNC:6833 HGNC:6834 HGNC:29079	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	10/20/19	2D 3D TSV
US10214524	20	19		2-heteroaryl carboxamides	Bayer Intellectual Property GmbH	10/20/19	2D 3D TSV
US10214516	14	14		5-(N-fused tricyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	10/20/19	2D 3D TSV
US10214478	11	11		Amantadine nitrate compounds with neural protective effect, and preparation and medical use thereof	TBA	10/20/19	2D 3D TSV
US10214545	36	18		Amido-substituted imidazopyridazines useful in the treatment of hyper-proliferative and/or angiogenesis disorders	Bayer Pharma Aktiengesellschaft	10/20/19	2D 3D TSV
US10214509	35	18	HGNC:10593 HGNC:10597	Amino-substituted heterocyclic derivatives as sodium channel inhibitors	Almirall, S.A.	10/20/19	2D 3D TSV
US10214536	76	76	HGNC:11584	Amlexanox analogs	The Regents of the University of Michigan	10/20/19	2D 3D TSV
US9822124	255	85	HGNC:19310 HGNC:8987	Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors	Incyte Corporation	10/20/19	2D 3D TSV
US10214537	824	774	HGNC:8977	Bicyclic heteroaryl amine compounds	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10214528	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	10/20/19	2D 3D TSV
US10214546	213	174	HGNC:1133	Btk inhibitors	Merck Sharp & Dohme Corp	10/20/19	2D 3D TSV
US10214507	138	137	HGNC:8846	Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators	Reset Therapeutics, Inc.	10/20/19	2D 3D TSV
US10220048	100	97	HGNC:9665	Compositions and methods for treating ocular diseases	Aerpio Therapeutics Inc	10/20/19	2D 3D TSV
US10213407	9	9		Compounds and methods for inhibiting production of trimethylamine	The Procter & Gamble Company	10/20/19	2D 3D TSV
US10220040	9	9		Compounds, compositions and methods useful for cholesterol mobilization	Cerenis Therapeutics Holding SA	10/20/19	2D 3D TSV
US9822074	99	94	HGNC:7045	Dihydropyridinone MGAT2 inhibitors	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10214512	386	227	HGNC:3529 HGNC:6357	Factor XIA inhibitors	Merck Sharp & Dohme Corp	10/20/19	2D 3D TSV
US10214492	511	238	HGNC:10924 HGNC:10922	Heterocyclic inhibitors of MCT4	Vettore, LLC	10/20/19	2D 3D TSV
US10214535	32	16	HGNC:4849 HGNC:4848	Hydroxmethyl piperidine orexin receptor antagonists	Merck Sharp & Dohme Corp	10/20/19	2D 3D TSV
US10214544	155	154	HGNC:3540	Imidazopyridazine and imidazothiadiazole compounds	Universite de Montreal	10/20/19	2D 3D TSV
US9822068	26	13	HGNC:3553	Inhibitors of fatty acid amide hydrolase (FAAH) enzyme with improved oral bioavailability and their use as medicaments	University of California	10/20/19	2D 3D TSV
US10221129	293	288		Inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	10/20/19	2D 3D TSV
US9822103	94	92	HGNC:3527	Inhibitors of lysine methyl transferase	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10221161	192	94	HGNC:6371 HGNC:6357	Inhibitors of plasma kallikrein	Kalvista Pharmaceuticals Limited	10/20/19	2D 3D TSV
US10221160	12	4	HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Mycovia Pharmaceuticals, Inc.	10/20/19	2D 3D TSV
US9820989	119	88	HGNC:6307 HGNC:8804	Method of treating conditions with kinase inhibitors	Allergan Inc	10/20/19	2D 3D TSV
US10214533	23	7	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders	Ogeda SA	10/20/19	2D 3D TSV
US10213421	10	10	HGNC:1604	Pharmaceutical formulations comprising CCR3 antagonists	Alkahest, Inc.	10/20/19	2D 3D TSV
US10214519	354	327	HGNC:8980	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	10/20/19	2D 3D TSV
US9822120	64	32	HGNC:1133	Protein kinase inhibitors	Pharmascience Inc	10/20/19	2D 3D TSV
US10214518	8	6	HGNC:9602	Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	10/20/19	2D 3D TSV
US10221156	6	6		Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	10/20/19	2D 3D TSV
US10214511	56	3	HGNC:9077 HGNC:11283 HGNC:11584 HGNC:14552 HGNC:17967 HGNC:12434 HGNC:6735 HGNC:2451 HGNC:5465 HGNC:4617 HGNC:2459 HGNC:6112 HGNC:2457 HGNC:3765 HGNC:6190 HGNC:6192 HGNC:6193 HGNC:6171 HGNC:11390 HGNC:12440 HGNC:1079 HGNC:1133 HGNC:1771 HGNC:6860 HGNC:11719 HGNC:7972 HGNC:1774 HGNC:6524 HGNC:1775	Quinazolines as potassium ion channel inhibitors	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10213433	373	370	HGNC:990	Solid dispersions containing an apoptosis-inducing agent	AbbVie Inc	10/20/19	2D 3D TSV
US10214534	44	44		Substituted 2-phenyl (AZA)benzofuran compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10213416	11	11	HGNC:735	Substituted benzoxazolone derivatives as acid ceramidase inhibitors, and their use as medicaments	University of Chicago	10/20/19	2D 3D TSV
US10213427	107	107	HGNC:3690	Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3	Incyte Corporation	10/20/19	2D 3D TSV
US9822102	357	143	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders	Bayer Pharma Aktiengesellschaft	10/20/19	2D 3D TSV
US10221142	124	118		Substituted pyrazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	10/20/19	2D 3D TSV
US10214515	36	9	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Substituted pyrazoles as inhibitors of fibroblast growth factor receptor	Zhejiang Hisun Pharmaceutical Co., Ltd	10/20/19	2D 3D TSV
US10221146	424	411		Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation	10/20/19	2D 3D TSV
US10221162	788	507	HGNC:339	Triazole agonists of the APJ receptor	Amgen Inc	10/20/19	2D 3D TSV
US10214527	94	65	HGNC:7218	Triazolopyridine inhibitors of myeloperoxidase	Bristol-Myers Squibb Co.	10/20/19	2D 3D TSV
US10214530	118	57	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN	10/20/19	2D 3D TSV
US9815850	266	255		Compounds, compositions and methods	Denali Therapeutics Inc.	10/14/19	2D 3D TSV
US9815836	74	33	HGNC:17967	Macrocyclic compounds as IRAK1/4 inhibitors and uses thereof	Merck Patent GmbH	10/14/19	2D 3D TSV
US9815840	24	24	HGNC:7029	Protein kinase inhibitor containing pyrrolopyridazine derivative	The Asan Foundation	10/14/19	2D 3D TSV
US9815842	127	126	HGNC:6819	Pyrazolo pyrimidine derivatives and their use as MALT1 inhibitors	Novartis AG	10/14/19	2D 3D TSV
US9815861	12	12	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	10/14/19	2D 3D TSV
US9815846	228	227	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	10/14/19	2D 3D TSV
US9815832	184	92	HGNC:8781 HGNC:8783	Azabenzimidazole compounds	Pfizer Inc	10/13/19	2D 3D TSV
US9815790	48	23	HGNC:2160 HGNC:2159	Chemically modified quinoline and quinolone derivatives useful as CB-1 inverse agonists	Janssen Pharmaceutica NV	10/13/19	2D 3D TSV
US9815819	87	76	HGNC:2771	Complement pathway modulators and uses thereof	Novartis AG	10/13/19	2D 3D TSV
US9814715	14	7	HGNC:7966 HGNC:7965	Liver X receptor modulators	Vitae Pharamceuticals, Inc.	10/13/19	2D 3D TSV
US9815796	1267	689		Pyrimidone carboxamide compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	10/13/19	2D 3D TSV
US9815834	91	91	HGNC:3688	Quinolone derivatives as fibroblast growth factor receptor inhibitors	Principia Biopharma Inc	10/13/19	2D 3D TSV
US9815820	30	7	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation LLC	10/13/19	2D 3D TSV
US9814704	167	166	HGNC:6850	Substituted pyrrolo[2,3-b]pyridines as MLK inhibitors	The University of Rochester	10/13/19	2D 3D TSV
US9809582	68	24	HGNC:8781 HGNC:1952	Aminoester derivatives	Chiesi Farmaceutici S.p.A.	10/07/19	2D 3D TSV
US9809568	7	7	HGNC:18618	Compounds inhibiting leucine-rich repeat kinase enzyme activity	Merck Sharp & Dohme Corp	10/07/19	2D 3D TSV
US9809572	16	1	HGNC:427	Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds	Suzhou Zelgen Biopharmaceuticals Co., Ltd.	10/07/19	2D 3D TSV
US9808445	32	30	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	10/07/19	2D 3D TSV
US9809545	25	25	HGNC:3551	Factor XIa inhibitors	Merck Sharp & Dohme Corp	10/07/19	2D 3D TSV
US9809574	248	248	HGNC:990	Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	10/07/19	2D 3D TSV
US9809583	31	31		Oxazolidine-based compound and selective androgen receptor agonist comprising same	DONG-A ST CO., LTD	10/07/19	2D 3D TSV
US9809561	424	422		Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Merck Sharp & Dohme Corp	10/07/19	2D 3D TSV
US9802907	47	44	HGNC:12805	2-aryl selenazole compound and pharmaceutical composition thereof	JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD.	10/01/19	2D 3D TSV
US9802947	18	9	HGNC:2536 HGNC:2545	3-oxo-tetrahydro-furo[3,2-b]pyrrol-4(5H)-yl) derivatives II	GRÜNENTHAL GMBH	10/01/19	2D 3D TSV
US9802924	43	43	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	10/01/19	2D 3D TSV
US9802944	68	34	HGNC:10555	Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffmann-La Roche Inc	10/01/19	2D 3D TSV
US9801889	200	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	10/01/19	2D 3D TSV
US9802928	48	24	HGNC:934 HGNC:933	C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	10/01/19	2D 3D TSV
US9802960	484	476	HGNC:8974	Heteroaryls and uses thereof	Millennium Pharmaceuticals Inc	10/01/19	2D 3D TSV
US9802945	23	23	HGNC:4076	Imidazopyridazine derivatives as modulators of the GABAA receptor activity	Pfizer Inc	10/01/19	2D 3D TSV
US9802915	262	215	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Co.	10/01/19	2D 3D TSV
US9802920	20	20	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Hoffman-La Roche Inc	10/01/19	2D 3D TSV
US9802904	64	62		Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof	The United States of America, as represented by the Secretary, Department of Health and Human Services	10/01/19	2D 3D TSV
US9802939	77	77	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Co.	10/01/19	2D 3D TSV
US9802918	324	107	HGNC:19310 HGNC:8987	Pyridineamine compounds useful as Pim kinase inhibitors	Incyte Corporation	10/01/19	2D 3D TSV
US9801872	35	34	HGNC:1133	Pyridinyl and fused pyridinyl triazolone derivatives	Takeda Pharmaceutical Co., Ltd	10/01/19	2D 3D TSV
US9801888	129	129	HGNC:3942	Pyrimidine compounds as mTOR and PI3K inhibitors	Development Center for Biotechnology	10/01/19	2D 3D TSV
US9801878	34	32	HGNC:8772	Quinoline derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	10/01/19	2D 3D TSV
US9796719	321	219	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	Galapagos NV	09/24/19	2D 3D TSV
US9796741	168	167	HGNC:2771	Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	09/23/19	2D 3D TSV
US9796664	27	11	HGNC:4852 HGNC:4854 HGNC:4853	Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors	BioMarin Pharmaceutical Inc	09/23/19	2D 3D TSV
US9796729	36	33	HGNC:2843	Compounds as diacylglycerol acyltransferase inhibitors	GlaxoSmithKline	09/23/19	2D 3D TSV
US9796710	47	44		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals Inc	09/23/19	2D 3D TSV
US9796702	52	23	HGNC:2592 HGNC:2591	Dihydroquinoline pyrazolyl compounds	Hoffmann-La Roche Inc	09/23/19	2D 3D TSV
US9796700	349	344	HGNC:6877	ERK inhibitors and uses thereof	Celgene CAR LLC	09/23/19	2D 3D TSV
US9796680	41	31	HGNC:4177	Glucocerebrosidase modulators and uses thereof	Alectos Therapeutics Inc	09/23/19	2D 3D TSV
US9796720	31	31	HGNC:7978	Imidazole-derived modulators of the glucocorticoid receptor	Bristol-Myers Squibb Co.	09/23/19	2D 3D TSV
US9796706	505	173	HGNC:6881 HGNC:6872 HGNC:6886	Inhibitors of Jun N-terminal kinase	Imago Pharmaceuticals Inc	09/23/19	2D 3D TSV
US9796672	170	93	HGNC:8157	Isoindoline compositions and methods for treating neurodegenerative disease	COGNITION THERAPEUTICS, INC.	09/23/19	2D 3D TSV
US9796742	135	61	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Respivert Limited	09/23/19	2D 3D TSV
US9795611	60	59	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc	09/23/19	2D 3D TSV
US9796723	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc	09/23/19	2D 3D TSV
US9796707	36	36	HGNC:11305	Piperazine derivatives for treating disorders	The University of Nottingham	09/23/19	2D 3D TSV
US9795602	9	9	HGNC:9213	Polycyclic-carbamoylpyridone compounds and their pharmaceutical use	Gilead Sciences Inc	09/23/19	2D 3D TSV
US9795608	15	15	HGNC:1133	Protein kinase inhibitors	Pharmascience Inc	09/23/19	2D 3D TSV
US9796725	125	122	HGNC:30661	Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme	Millennium Pharmaceuticals Inc	09/23/19	2D 3D TSV
US9796732	42	42	HGNC:3942	Pyridopyrimidine or pyrimidopyrimidine compound, prepration method, pharmaceutical composition, and use thereof	SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.	09/23/19	2D 3D TSV
US9796708	1363	1352	HGNC:1780	Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors	AbbVie Inc	09/23/19	2D 3D TSV
US9795606	35	35	HGNC:7027	Pyrrolopyrimidine compounds for the treatment of cancer	University of North Carolina at Chapel Hill	09/23/19	2D 3D TSV
US9796687	18	18	HGNC:8791	S-substituted quinazolines and their therapeutic applications for the treatment of diseases mediated by PDE7	Consejo Superior de Investigaciones Cientificas	09/23/19	2D 3D TSV
US9796716	127	124	HGNC:1133	Selective inhibitors of Tec and Src protein kinase families	Pharmascience Inc	09/23/19	2D 3D TSV
US9796724	517	232	HGNC:8031 HGNC:12440	Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharma Inc	09/23/19	2D 3D TSV
US9796704	1540	275	HGNC:3763 HGNC:3430 HGNC:6307 HGNC:3386 HGNC:3395 HGNC:3236	Substituted quinazolines as receptor-type kinase inhibitors	SYMPHONY EVOLUTION, INC.	09/23/19	2D 3D TSV
US10208016	23	23		1-sulfonyl piperidine derivatives as modulators of prokineticin receptors	Takeda Pharmaceutical Co., Ltd	09/21/19	2D 3D TSV
US10208024	246	83	HGNC:3690 HGNC:3689 HGNC:3688	2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases	Array BioPharma Inc	09/21/19	2D 3D TSV
US10208044	3	3	HGNC:85	ACC inhibitors and uses thereof	GILEAD APOLLO, LLC	09/21/19	2D 3D TSV
US10208011	50	25	HGNC:4485	Benzothiophene estrogen receptor modulators	G1 Therapeutics, Inc.	09/21/19	2D 3D TSV
US10208081	137	133	HGNC:7967	Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof	Enanta Pharmaceuticals Inc	09/21/19	2D 3D TSV
US10206907	633	322		Compounds useful for the treatment of degenerative and inflammatory diseases	Galapagos NV	09/21/19	2D 3D TSV
US10208056	240	97	HGNC:19682 HGNC:1779	Condensed tricyclic compounds as protein kinase inhibitors	FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)	09/21/19	2D 3D TSV
US10208000	19	19		Eis inhibitors	University of Kentucky Research Foundation	09/21/19	2D 3D TSV
US10208040	34	11	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Fused imidazo-piperidine JAK inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	09/21/19	2D 3D TSV
US10208019	434	246	HGNC:4324	GLP-1 receptor agonists and uses thereof	Pfizer Inc	09/21/19	2D 3D TSV
US10208023	23	7	HGNC:10597	Heterocyclic inhibitors of the sodium channel	TBA	09/21/19	2D 3D TSV
US10208039	147	146	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	09/21/19	2D 3D TSV
US10208066	156	68	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Imidazopyridazine compounds and their use	Hutchison MediPharma Limited	09/21/19	2D 3D TSV
US10208060	10	10	HGNC:1232	Inhibitors of HIF prolyl hydroxylase	Merck Sharp & Dohme Corp	09/21/19	2D 3D TSV
US10207999	226	119	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	09/21/19	2D 3D TSV
US10208064	36	36	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	WuXi AppTec (Shanghai) Co. Ltd	09/21/19	2D 3D TSV
US10207991	170	93	HGNC:8157	Isoindoline compositions and methods for treating neurodegenerative disease	COGNITION THERAPEUTICS, INC.	09/21/19	2D 3D TSV
US10208068	46	46	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Co.	09/21/19	2D 3D TSV
US10208043	31	31		Methods for inhibiting fascin	Cornell University	09/21/19	2D 3D TSV
US10208027	4	1	HGNC:882	Processes for preparing ATR inhibitors	Vertex Pharmaceuticals Inc	09/21/19	2D 3D TSV
US10208020	126	62	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics SA	09/21/19	2D 3D TSV
US10208021	21	21	HGNC:3529	Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors	Bristol-Myers Squibb Co.	09/21/19	2D 3D TSV
US10208047	36	35	HGNC:1133	Tertiary alcohol imidazopyrazine BTK inhibitors	Merck Sharp & Dohme Corp	09/21/19	2D 3D TSV
US10206931	611	311	HGNC:2348	Therapeutic compounds and uses thereof	Genentech Inc	09/21/19	2D 3D TSV
US10208071	189	187	HGNC:3827	Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases	Allergan Inc	09/21/19	2D 3D TSV
US9789094	21	21	HGNC:6059	1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase	Incyte Holdings Corporation	09/09/19	2D 3D TSV
US9790230	212	106		2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives	Hoffmann-La Roche Inc	09/09/19	2D 3D TSV
US9790229	360	356	HGNC:1133	Bruton's tyrosine kinase inhibitors	Sunesis Pharmaceuticals Inc	09/09/19	2D 3D TSV
US9790233	21	19	HGNC:5154	Compositions and methods of modulating 15-PGDH activity	Case Western Reserve University	09/09/19	2D 3D TSV
US9789116	96	91	HGNC:5154	Compositions and methods of modulating short-chain dehydrogenase activity	Case Western Reserve University	09/09/19	2D 3D TSV
US9789100	132	45		Compounds as rearranged during transfection (RET) inhibitors	GlaxoSmithKline	09/09/19	2D 3D TSV
US9789110	55	55	HGNC:16940	Diacylglycerol acyltransferase 2 inhibitors	Pfizer Inc	09/09/19	2D 3D TSV
US9790212	110	72		Enhancer of zeste homolog 2 inhibitors	GlaxoSmithKline	09/09/19	2D 3D TSV
US9790221	574	287	HGNC:17967	Heteroaryl compounds as IRAK inhibitors and uses thereof	Merck Patent GmbH	09/09/19	2D 3D TSV
US9790228	640	194	HGNC:8979 HGNC:8978 HGNC:8972 HGNC:8977	Heterocyclic kinase inhibitors	Intellikine LLC	09/09/19	2D 3D TSV
US9790203	25	25	HGNC:8772	Inhibitor compounds of phosphodiesterase type 10A	AbbVie Inc	09/09/19	2D 3D TSV
US9790174	318	118	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Respivert Limited	09/09/19	2D 3D TSV
US9790209	47	17	HGNC:11491 HGNC:11283 HGNC:4616	Kinase inhibitors	Respivert Limited	09/09/19	2D 3D TSV
US9790196	12	4	HGNC:6833 HGNC:6834 HGNC:29079	Lysine demethylase inhibitors for diseases and disorders associated with Flaviviridae	Oryzon Genomics, S.A.	09/09/19	2D 3D TSV
US9790235	133	130	HGNC:6887	MK2 inhibitors and uses thereof	Celgene CAR LLC	09/09/19	2D 3D TSV
US9791447	30	10	HGNC:17927 HGNC:30402 HGNC:23116	Methods of identifying SENP1 inhibitors	City of Hope	09/09/19	2D 3D TSV
US9790201	119	113		Piperidine and azepine derivatives as prokineticin receptor modulators	Takeda Pharmaceutical Co., Ltd	09/09/19	2D 3D TSV
US9790180	126	41	HGNC:4852 HGNC:4854 HGNC:4853	Piperidine derivatives as HDAC1/2 inhibitors	REGENACY PHARMACEUTICALS, LLC	09/09/19	2D 3D TSV
US9790217	174	85	HGNC:2592 HGNC:2591	Pyridinyloxy- and phenyloxy-pyrazolyl compounds	Hoffmann-La Roche Inc	09/09/19	2D 3D TSV
US9789082	100	20	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin receptor subtype 4 (SSTR4) agonists	Centrexion Therapeutics Corporation	09/09/19	2D 3D TSV
US9790198	102	98	HGNC:4498	Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes	Janssen Pharmaceutica NV	09/09/19	2D 3D TSV
US9790220	49	25	HGNC:4849 HGNC:4848	Substituted cyclopentanes, tetrahydrofuranes and pyrrolidines as orexin receptor antagonists	Takeda Pharmaceutical Co., Ltd	09/09/19	2D 3D TSV
US9790158	24	12	HGNC:14063 HGNC:13315	Substituted tropolone derivatives and methods of use	University of Connecticut	09/09/19	2D 3D TSV
US10202412	19	16		β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections	Atea Pharmaceuticals, Inc.	09/02/19	2D 3D TSV
US10202369	883	393	HGNC:2596 HGNC:2637 HGNC:2625 HGNC:8534 HGNC:2622 HGNC:2623	1,3-thiazol-2-yl substituted benzamides	Bayer Aktiengesellschaft	09/02/19	2D 3D TSV
US10202365	79	39	HGNC:9967	2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors	BLUEPRINT MEDICINES CORPORATION	09/02/19	2D 3D TSV
US10202411	20	15		3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV	IDENIX PHARMACEUTICALS LLC	09/02/19	2D 3D TSV
US10202377	207	115		3-(1H-benzo[D]imidazol-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof	Samumed, LLC	09/02/19	2D 3D TSV
US10202383	46	46	HGNC:3009	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions	Boehringer Ingelheim International GmbH	09/02/19	2D 3D TSV
US10202370	154	153	HGNC:6342	Benzimidazole derivatives as selective proteine kinase inhibitors	AB SCIENCE	09/02/19	2D 3D TSV
US10202368	88	88	HGNC:23692	CXCR7 receptor modulators	IDORSIA PHARMACEUTICALS Ltd	09/02/19	2D 3D TSV
US10202399	34	34	HGNC:2671	Dihydroxy aromatic heterocyclic compound	Takeda Pharmaceutical Co., Ltd	09/02/19	2D 3D TSV
US10202388	53	43	HGNC:11708 HGNC:6059	Fused-ring compounds, pharmaceutical composition and uses thereof	Shanghai De Novo Pharmatech Co., Ltd	09/02/19	2D 3D TSV
US10202390	29	28	HGNC:6266	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Co.	09/02/19	2D 3D TSV
US10202373	49	49	HGNC:8974	Heteroaryls and uses thereof	Millennium Pharmaceuticals Inc	09/02/19	2D 3D TSV
US10202367	71	62		Heterocyclic compounds and methods of use thereof	The United States of America, as represented by the Secretary, Department of Health and Human Services	09/02/19	2D 3D TSV
US10202381	147	145	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	09/02/19	2D 3D TSV
US10202418	29	20	HGNC:9958 HGNC:2529	Hydroxy-ethylene derivatives for the treatment of arthrosis	Merck Patent GmbH	09/02/19	2D 3D TSV
US10202362	4	2	HGNC:2528 HGNC:6710	Inhibitors of leukotriene A4 hydrolase	Celtaxsys, Inc.	09/02/19	2D 3D TSV
US10202350	187	81	HGNC:10924 HGNC:23357	MCT4 inhibitors for treating disease	Vettore, LLC	09/02/19	2D 3D TSV
US10202403	19	18		Macrocyclic benzofuran compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	09/02/19	2D 3D TSV
US10202375	36	26		N-pyridinyl acetamide derivatives as Wnt signalling pathway inhibitors	Redx Pharma PLC	09/02/19	2D 3D TSV
US10202371	151	19	HGNC:8978 HGNC:8975 HGNC:3942 HGNC:8977 HGNC:8976	Oxazolidin-2-one-pyrimidine derivatives and the use thereof as phosphatidylinositol-3-kinase inhibitors	Novartis AG	09/02/19	2D 3D TSV
US10202404	128	127		Polycyclic pyridone derivative having integrase inhibitory activity	Shionogi & Co., Ltd	09/02/19	2D 3D TSV
US10202389	125	120	HGNC:12469	Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme	Millennium Pharmaceuticals Inc	09/02/19	2D 3D TSV
US10202379	784	388	HGNC:11535	Substituted polycyclic carbamoyl pyridone derivative prodrug	Shionogi & Co., Ltd	09/02/19	2D 3D TSV
US10202360	382	361	HGNC:2348	Therapeutic compounds	Celgene Quanticel Research Inc	09/02/19	2D 3D TSV
US10202354	120	120	HGNC:13610	Therapeutic compounds and uses thereof	Genentech Inc	09/02/19	2D 3D TSV
US10202378	434	200		Therapeutic compounds and uses thereof	Genentech Inc	09/02/19	2D 3D TSV
US9783488	107	107	HGNC:14063	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	08/20/19	2D 3D TSV
US9783501	80	80	HGNC:10582	Substituted quinolines as modulators of sodium channels	Vertex Pharmaceuticals Inc	08/20/19	2D 3D TSV
US9783543	38	19	HGNC:7110	Aminoimidazopyridazines	Bayer Pharma Aktiengesellschaft	08/19/19	2D 3D TSV
US9783530	84	40	HGNC:3529 HGNC:6357	Factor Xla inhibitors	Merck Sharp & Dohme Corp	08/19/19	2D 3D TSV
US9783573	132	66	HGNC:592	IAP antagonists	Bristol-Myers Squibb Co.	08/19/19	2D 3D TSV
US9783527	470	356	HGNC:10582 HGNC:10597	Indazole ureas and method of use	AbbVie Inc	08/19/19	2D 3D TSV
US9783556	68	22	HGNC:11491 HGNC:11283 HGNC:4616	Kinase inhibitors	Respivert Limited	08/19/19	2D 3D TSV
US9783524	48	10	HGNC:427 HGNC:3236	Protein tyrosine kinase modulators and methods of use	Betta Pharmaceuticals Co., Ltd	08/19/19	2D 3D TSV
US9783551	11	9	HGNC:9642	Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease	Glaceum Inc.	08/19/19	2D 3D TSV
US9783511	263	255		Carbamate benzoxazine propionic acids and acid derivatives for modulation of RORgamma activity and the treatment of disease	Lycera Corporation	08/18/19	2D 3D TSV
US9783500	109	18	HGNC:7872 HGNC:7873	2-aminoquinoline-based compounds for potent and selective neuronal nitric oxide synthase inhibition	Northwestern University	08/17/19	2D 3D TSV
US9783499	24	24	HGNC:7029	Quinoline derivatives and their applications	Shenyang Pharmaceutical University	08/17/19	2D 3D TSV
US9782415	530	232	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031	Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharma Inc	08/17/19	2D 3D TSV
US9777004	61	33		Amino-substituted imidazopyridazines	Bayer Intellectual Property GmbH	08/13/19	2D 3D TSV
US9777020	185	185	HGNC:8031	Furo-3-carboxamide derivatives and methods of use	AbbVie Inc	08/13/19	2D 3D TSV
US9777008	310	306	HGNC:29652	PRMT5 inhibitors and uses thereof	Epizyme Inc	08/13/19	2D 3D TSV
US9777010	124	111	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	Columbia University	08/13/19	2D 3D TSV
US9777017	196	90	HGNC:6190 HGNC:6192	Tricyclic fused thiophene derivatives as JAK inhibitors	Incyte Holdings Corporation	08/13/19	2D 3D TSV
US9776995	524	366	HGNC:10593 HGNC:10597	Bicyclic sulfonamide compounds as sodium channel inhibitors	Amgen Inc	08/12/19	2D 3D TSV
US9776990	146	73	HGNC:13575	Isoindolone derivatives	AbbVie Inc	08/12/19	2D 3D TSV
US9777000	173	158	HGNC:8772	Pyrazole derivative	Mochida Pharmaceutical Co., Ltd	08/12/19	2D 3D TSV
US9776991	211	206	HGNC:3402	Thienomethylpiperazine derivatives as inhibitors of soluble epoxide hydrolase	Sanofi	08/12/19	2D 3D TSV
US9777003	544	269		Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	08/12/19	2D 3D TSV
US9775839	42	41	HGNC:11491	2-pyrazine carboxamides as spleen tyrosine kinase inhibitors	Merck Sharp & Dohme Corp	08/11/19	2D 3D TSV
US9775844	440	109	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals Inc	08/11/19	2D 3D TSV
US9776974	122	119	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	08/11/19	2D 3D TSV
US9776988	32	8	HGNC:6307 HGNC:3690 HGNC:3689 HGNC:3688	Pyrazolylbenzo[d]imidazole derivatives	Celon Pharma S.A.	08/11/19	2D 3D TSV
US9771369	502	253	HGNC:6342	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	08/06/19	2D 3D TSV
US9771375	159	156		Indazole compounds useful as ketohexokinase inhibitors	Janssen Pharmaceutica NV	08/06/19	2D 3D TSV
US9771353	39	14	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6874	Kinase inhibitors based upon N-alkyl pyrazoles	Topivert Pharma Limited	08/06/19	2D 3D TSV
US9771379	28	28	HGNC:933	N-(2-(2-amino-6-substituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]OXAZIN-8a(8H)-yl)-thiazol-4-yl) amides	Pfizer Inc	08/06/19	2D 3D TSV
US9771376	56	51	HGNC:10593 HGNC:10597	N-substituted benzamides and methods of use thereof	Genentech Inc	08/06/19	2D 3D TSV
US9771359	37	33	HGNC:12716	Substituted oxazole- and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II	Medifron DBT Inc.	08/06/19	2D 3D TSV
US9771366	28	20	HGNC:10435 HGNC:10431 HGNC:10430 HGNC:10432	Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors	PHOENIX MOLECULAR DESIGN	08/06/19	2D 3D TSV
US9771320	334	293		Carbocyclic sulfone RORγ modulators	Bristol-Myers Squibb Co.	08/05/19	2D 3D TSV
US9771329	122	119	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	08/05/19	2D 3D TSV
US9771316	35	17	HGNC:11063	Phenoxyalkylamine compound	Osaka University	08/02/19	2D 3D TSV
US9763922	595	308	HGNC:13575 HGNC:2348	Therapeutic compounds and uses thereof	Genentech Inc	07/30/19	2D 3D TSV
US9765057	34	14	HGNC:4849 HGNC:4848	3-ester-4 substituted orexin receptor antagonists	Merck Sharp & Dohme Corp	07/29/19	2D 3D TSV
US9765037	344	136	HGNC:4840 HGNC:11283 HGNC:76	Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases	University of Washington Through its Center for Commercialization	07/29/19	2D 3D TSV
US9765038	62	23	HGNC:3236	Heteroaryl compounds and uses thereof	Celgene CAR LLC	07/29/19	2D 3D TSV
US9765054	75	74	HGNC:14063	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	07/29/19	2D 3D TSV
US9765056	173	173	HGNC:990	Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	07/29/19	2D 3D TSV
US9765068	193	193	HGNC:10894	PRMT5 inhibitors and uses thereof	Epizyme Inc	07/29/19	2D 3D TSV
US9765060	118	113	HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	07/29/19	2D 3D TSV
US9765029	40	37	HGNC:10597	Pyridine compounds as sodium channel blockers	Purdue Pharma LP	07/29/19	2D 3D TSV
US9765058	20	19	HGNC:1148	Substituted benzylpyrazoles	Bayer Pharma Aktiengesellschaft	07/29/19	2D 3D TSV
US9765070	81	39	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives	Bayer Pharma Aktiengesellschaft	07/29/19	2D 3D TSV
US9765040	15	15		Therapeutic agent for pain	Astellas Pharma Inc	07/29/19	2D 3D TSV
US9765092	444	442	HGNC:12008	Tricyclic piperidine compounds	Actelion Pharmaceuticals Ltd	07/29/19	2D 3D TSV
US9763957	206	201	HGNC:10548	Autotaxin inhibitors	Novartis AG	07/26/19	2D 3D TSV
US9763952	568	262	HGNC:8975 HGNC:8977	Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives	Novartis AG	07/26/19	2D 3D TSV
US9765018	65	65	HGNC:6059	IDO inhibitors	Bristol-Myers Squibb Co.	07/26/19	2D 3D TSV
US9763943	43	43	HGNC:8031	Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	07/26/19	2D 3D TSV
US9758480	44	44	HGNC:3529	1-(cycloalkyl-carbonyl)proline derivative	Sumitomo Dainippon Pharma Co., Ltd	07/22/19	2D 3D TSV
US9758508	11	11	HGNC:1133	2,3-dihydro-isoindole-1-on derivative as BTK kinase suppressant, and pharmaceutical composition including same	CrystalGenomics, Inc.	07/22/19	2D 3D TSV
US9758505	35	35	HGNC:11708	3-(indol-3-yl)-pyridine derivatives, pharmaceutical compositions and methods for use	iTeos Therapeutics	07/22/19	2D 3D TSV
US9758524	664	132	HGNC:6735 HGNC:4037 HGNC:1133 HGNC:11283 HGNC:6524	4-imidazopyridazin-1-yl-benzamides as Btk inhibitors	Merck Sharp & Dohme B.V.	07/22/19	2D 3D TSV
US10202344	88	67	HGNC:10597	Aryl substituted indoles and the use thereof	Purdue Pharma LP	07/22/19	2D 3D TSV
US10201527	144	95	HGNC:4852 HGNC:4774 HGNC:13315	Benzimidazole derivatives: preparation and pharmaceutical applications	Mei Pharma Inc	07/22/19	2D 3D TSV
US9758537	116	116	HGNC:2771	Compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	07/22/19	2D 3D TSV
US9757383	30	15	HGNC:286 HGNC:1952	Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities	Almirall, S.A.	07/22/19	2D 3D TSV
US10202340	49	17	HGNC:12524	Glucosylceramide synthase inhibitors and therapeutic methods using the same	The Regents of the University of Michigan	07/22/19	2D 3D TSV
US9758495	7	7		Heteroaryl acid morpholinone compounds as MDM2 inhibitors for the treatment of cancer	Amgen Inc	07/22/19	2D 3D TSV
US9757369	28	27	HGNC:4617	Heterocyclic GSK-3 allosteric modulators	Consejo Superior de Investigaciones Cientificas (CSIC)	07/22/19	2D 3D TSV
US9758517	21	21	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	07/22/19	2D 3D TSV
US10202330	54	18	HGNC:6833 HGNC:6834 HGNC:29079	Lysine specific demethylase-1 inhibitors and their use	Oryzon Genomics, S.A.	07/22/19	2D 3D TSV
US9757364	370	71	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Naphthyridine derivative compounds	Astex Therapeutics Ltd	07/22/19	2D 3D TSV
US9758483	160	159	HGNC:10582	Pyridone amides as modulators of sodium channels	Vertex Pharmaceuticals Inc	07/22/19	2D 3D TSV
US9758538	157	153	HGNC:8979	Pyrimidine derivatives	Pfizer Inc	07/22/19	2D 3D TSV
US10201546	769	362		Quinolinyl modulators of RORγt	Janssen Pharmaceutica NV	07/22/19	2D 3D TSV
US10201545	102	102		Styrenyl derivative compounds for treating ophthalmic diseases and disorders	ACUCELA INC.	07/22/19	2D 3D TSV
US10202339	353	350		Therapeutic compounds and compositions	Agios Pharmaceuticals Inc	07/22/19	2D 3D TSV
US9758523	20	20	HGNC:29079	Triazolopyridines and triazolopyrazines as LSD1 inhibitors	Incyte Corporation	07/22/19	2D 3D TSV
US9751886	33	10	HGNC:934 HGNC:933	4-amino-6-phenyl-6,7-dihydro[1,2,3]triazolo[1,5-A]pyrazine derivatives as inhibitors of beta-secretase (BACE)	Janssen Pharmaceutica NV	07/11/19	2D 3D TSV
US9751873	161	138		Aryl sultam derivatives as RORc modulators	Genentech Inc	07/11/19	2D 3D TSV
US9751885	801	224	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	07/11/19	2D 3D TSV
US9751856	6	6		Ethynyl derivatives	Hoffmann-La Roche Inc	07/11/19	2D 3D TSV
US9751854	484	477	HGNC:8974	Heteroaryls and uses thereof	Millennium Pharmaceuticals Inc	07/11/19	2D 3D TSV
US9751888	236	58	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals Inc	07/11/19	2D 3D TSV
US9751881	118	115	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	07/11/19	2D 3D TSV
US9751837	187	70	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Respivert Limited	07/11/19	2D 3D TSV
US9750744	68	47	HGNC:8031	Macrocyclic compounds as Trk kinase inhibitors	Array BioPharma Inc	07/11/19	2D 3D TSV
US9750748	14	14	HGNC:2671	Pyridazinones as DAAO enzyme inhibitors	Takeda Pharmaceutical Co., Ltd	07/11/19	2D 3D TSV
US9751832	42	21	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	07/11/19	2D 3D TSV
US9751843	148	148	HGNC:2097	Substituted uracils and use thereof	Bayer Pharma Aktiengesellschaft	07/11/19	2D 3D TSV
US9751850	11	11	HGNC:497	TRPA1 antagonists	AbbVie Inc	07/11/19	2D 3D TSV
US9744173	132	114	HGNC:933 HGNC:2625	2-amino 6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides	Pfizer Inc	07/05/19	2D 3D TSV
US9745284	120	59	HGNC:4849 HGNC:4848	2-pyridyloxy-4-ether orexin receptor antagonists	Merck Sharp & Dohme Corp	07/05/19	2D 3D TSV
US9745265	128	126		4-heteroaryl substituted benzoic acid compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	07/05/19	2D 3D TSV
US9745289	262	62	HGNC:2592 HGNC:2591	Aldosterone synthase inhibitors	Boehringer Ingelheim International GmbH	07/05/19	2D 3D TSV
US9745304	64	32		Amidoimidazopyridazines as MKNK-1 kinase inhibitors	Bayer Pharma Aktiengesellschaft	07/05/19	2D 3D TSV
US9744252	20	20	HGNC:6138	Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi	PIRAMAL IMAGING SA	07/05/19	2D 3D TSV
US9745307	46	45	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp	07/05/19	2D 3D TSV
US9745328	898	885	HGNC:3650	Flap modulators	Janssen Pharmaceutica NV	07/05/19	2D 3D TSV
US9745321	142	140	HGNC:8977	Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof	Shanghai Yingli Pharmaceutical Co., Ltd	07/05/19	2D 3D TSV
US9745317	28	23	HGNC:3020	Heterocyclic compounds and their use as dopamine D1 ligands	Pfizer Inc	07/05/19	2D 3D TSV
US9745310	199	198	HGNC:4597	Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same	SK Biopharmaceuticals Co. Ltd	07/05/19	2D 3D TSV
US9745324	83	44	HGNC:934 HGNC:933	Iminothiadiazepane dioxide compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	07/05/19	2D 3D TSV
US9745282	100	47	HGNC:2592 HGNC:2591	Indoline compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	07/05/19	2D 3D TSV
US9744148	96	90	HGNC:6368	Kallikrein 7 inhibitors	SIXERA Pharma AB	07/05/19	2D 3D TSV
US9745291	277	274	HGNC:29652	PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof	Epizyme Inc	07/05/19	2D 3D TSV
US9744172	287	286	HGNC:7027	Pyrazolopyrimidine compounds for the treatment of cancer	University of North Carolina at Chapel Hill	07/05/19	2D 3D TSV
US9745287	36	22	HGNC:10597	Pyrimidines and use thereof	Purdue Pharma LP	07/05/19	2D 3D TSV
US9745311	266	89	HGNC:3690 HGNC:3689 HGNC:3688	Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors	Incyte Corporation	07/05/19	2D 3D TSV
US9745283	328	169	HGNC:7029	Uracil derivatives as AXL and c-MET kinase inhibitors	IGNYTA, INC.	07/05/19	2D 3D TSV
US9738626	7	7	HGNC:9595	Antagonists of prostaglandin EP3 receptor	Pfizer Inc	07/01/19	2D 3D TSV
US9737516	44	18		Bicyclic heterocycles as bet protein inhibitors	Incyte Corporation	07/01/19	2D 3D TSV
US9738641	20	10	HGNC:6371 HGNC:6357	Bicyclic inhibitors	Kalvista Pharmaceuticals Limited	07/01/19	2D 3D TSV
US9737544	120	24	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Compounds	Astex Therapeutics Limited	07/01/19	2D 3D TSV
US9738658	36	36	HGNC:2843	Compounds as diacylglycerol acyltransferase inhibitors	GlaxoSmithKline	07/01/19	2D 3D TSV
US9738637	297	93	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quantical Research, Inc.	07/01/19	2D 3D TSV
US9738630	17	16	HGNC:3527	Inhibitors of lysine methyl transferase	Bristol-Myers Squibb Co.	07/01/19	2D 3D TSV
US9737522	17	17		NMDA receptor modulators and uses related thereto	Emory University	07/01/19	2D 3D TSV
US9738632	20	18	HGNC:7978	Phenyl and benzodioxinyl substituted indazoles derivatives	AstraZeneca AB	07/01/19	2D 3D TSV
US9738668	30	9		Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease	University of Kansas	07/01/19	2D 3D TSV
US9737542	111	111	HGNC:19679	Pyrrolotriazine kinase inhibitors	Bristol-Myers Squibb Co.	07/01/19	2D 3D TSV
US9738676	7	7	HGNC:8780	Selected macrolides with PDE4-inhibiting activity	Basilea Pharmaceutica AG	07/01/19	2D 3D TSV
US9737525	20	17	HGNC:10886	Small molecule activators of NRF2 pathway	The General Hospital Corporation	07/01/19	2D 3D TSV
US9738628	36	21		Substituted 1H-indazol-1-OL analogs as inhibitors of beta catenin/Tcf protein-protein interactions	University of Utah Research Foundation	07/01/19	2D 3D TSV
US9738640	16	8	HGNC:6833 HGNC:6834	Substituted benzamide derivatives as in vitro MAO-B inhibitors	NTZ Lab Ltd	07/01/19	2D 3D TSV
US9738649	771	379	HGNC:12716	Tetrahydro-pyrimidoazepines as modulators of TRPV1	Janssen Pharmaceutica NV	07/01/19	2D 3D TSV
US9738655	635	318	HGNC:6371 HGNC:3529	Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitors	Bristol-Myers Squibb Co.	07/01/19	2D 3D TSV
US9730929	33	33	HGNC:7110	Substituted aminoimidazopyridazines	Bayer Intellectual Property GmbH	06/26/19	2D 3D TSV
US9732104	43	43	HGNC:2771	Ether compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	06/24/19	2D 3D TSV
US9732037	63	21	HGNC:7872 HGNC:7873	2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors	Northwestern University	06/23/19	2D 3D TSV
US9732060	560	555	HGNC:8534	Aminotriazine derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	06/23/19	2D 3D TSV
US9732094	901	326	HGNC:6251 HGNC:9413	Arylquinazolines	Merck Patent GmbH	06/23/19	2D 3D TSV
US9732075	1982	990	HGNC:4849 HGNC:4848	Benzimidazole-proline derivatives	IDORSIA PHARMACEUTICALS Ltd	06/23/19	2D 3D TSV
US9732088	116	39	HGNC:934 HGNC:2529 HGNC:933	C2-carbocyclic iminothiazine dioxides as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	06/23/19	2D 3D TSV
US9732103	16	16	HGNC:2771	Carbamate, ester, and ketone compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	06/23/19	2D 3D TSV
US9732061	76	38	HGNC:2160 HGNC:2159	Cinnoline derivatives useful as CB-1 receptor inverse agonists	Janssen Pharmaceutica NV	06/23/19	2D 3D TSV
US9732087	30	30	HGNC:17383	Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine H4 receptor	Janssen Pharmaceutica NV	06/23/19	2D 3D TSV
US9732093	691	353	HGNC:3650	FLAP modulators	Janssen Pharmaceutica NV	06/23/19	2D 3D TSV
US9732066	239	237	HGNC:9599	Heterocyclic derivative and pharmaceutical drug	Nippon Shinyaku Co. Ltd	06/23/19	2D 3D TSV
US9730939	366	326	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	06/23/19	2D 3D TSV
US9732063	194	72	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6874	Kinase inhibitors	Respivert Limited	06/23/19	2D 3D TSV
US9732044	8	8	HGNC:644	N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use	Galderma Research & Development	06/23/19	2D 3D TSV
US9732072	30	29	HGNC:10894	PRMT5 inhibitors and uses thereof	Epizyme Inc	06/23/19	2D 3D TSV
US9732097	26	26	HGNC:6190	Process for the synthesis of a phosphoinositide 3-kinase inhibitor	Incyte Corporation	06/23/19	2D 3D TSV
US9730940	387	370	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme	06/23/19	2D 3D TSV
US9732085	36	33	HGNC:3529	Pyridinone and pyrimidinone derivatives as factor Xia	Ono Pharmaceutical Co., Ltd	06/23/19	2D 3D TSV
US9730931	144	67	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	Eisai R&D Management Co., Ltd	06/23/19	2D 3D TSV
US9730934	33	11	HGNC:3432 HGNC:3430 HGNC:3236	Quinazoline derivatives substituted by aniline, preparation method and use thereof	Xuanzhu Pharma Co., Ltd	06/23/19	2D 3D TSV
US9730937	1155	377	HGNC:9829 HGNC:1097	RAF kinase modulator compounds and methods of use thereof	Ambit Biosciences Corporation	06/23/19	2D 3D TSV
US9732092	23	23	HGNC:10966	Substituted 2,3,4,5,7,9,13,13a-octahydropyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]OXAZEPINES and methods for treating viral infections	Gilead Sciences Inc	06/23/19	2D 3D TSV
US10196387	88	87	HGNC:13575	Carbazole compounds useful as bromodomain inhibitors	Bristol-Myers Squibb Co.	06/16/19	2D 3D TSV
US10196396	240	174	HGNC:268 HGNC:262 HGNC:263	Compounds antagonizing A3 adenosine receptor, method for preparing them, and medical-use thereof	HANDOK INC.	06/16/19	2D 3D TSV
US10196436	116	57	HGNC:3691 HGNC:3688	Inhibitors of the fibroblast growth factor receptor	BLUEPRINT MEDICINES CORPORATION	06/16/19	2D 3D TSV
US10196393	56	6	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	THERAVANCE BIOPHARMA R&D IP, LLC	06/16/19	2D 3D TSV
US10196404	3	1	HGNC:6943	MCL-1 inhibitors and methods of use thereof	AstraZeneca AB	06/16/19	2D 3D TSV
US10196390	466	233	HGNC:6192 HGNC:12440	TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	06/16/19	2D 3D TSV
US10196391	120	119		Tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis B virus infection	Hoffmann-La Roche Inc	06/16/19	2D 3D TSV
US10196374	50	24	HGNC:7978 HGNC:11892	1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as SGRM modulators	AstraZeneca AB	06/14/19	2D 3D TSV
US10196354	127	127		4-heteroaryl substituted benzoic acid compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	06/14/19	2D 3D TSV
US10196381	41	41	HGNC:270	Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition containing the same, preparation method and use thereof	SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD	06/14/19	2D 3D TSV
US10196353	10	10	HGNC:8910	Chemical compounds	GlaxoSmithKline	06/14/19	2D 3D TSV
US10196378	44	9	HGNC:11283 HGNC:76	Inhibitors of BCR-ABL mutants and use thereof	The Regents of the University of Michigan	06/14/19	2D 3D TSV
US10196365	22	11	HGNC:3430 HGNC:3236	Quinazoline derivative, preparation method therefor, and pharmaceutical composition and application thereof	ARROMAX PHARMATECH CO., LTD.	06/14/19	2D 3D TSV
US10196369	103	102	HGNC:3128	Spirocyclic EBI2 modulators	Sanford Burnham Prebys Medical Discovery Institute	06/14/19	2D 3D TSV
US10196373	93	86	HGNC:11364	Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein	THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO	06/14/19	2D 3D TSV
US10196383	8	4	HGNC:4849 HGNC:4848	Substituted quinazoline compounds and preparation and uses thereof	Sunshine Lake Pharma Co., Ltd	06/14/19	2D 3D TSV
US10196385	3	3	HGNC:20088	Tetrahydropyranyl benzamide derivatives	Eli Lilly and Company	06/14/19	2D 3D TSV
US10196382	6	6		bis-Pyridazine compounds and their use in treating cancer	AstraZeneca AB	06/14/19	2D 3D TSV
US9724347	120	32	HGNC:4840 HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:6874	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl) ureas as P38 MAP knase inhibitors	Respivert Ltd	06/12/19	2D 3D TSV
US9725459	175	89	HGNC:2536 HGNC:2545	3-oxo-tetrahydro-furo[3,2-B]pyrrol-4(5H)-yl) derivatives I	GRUNENTHAL GMBH	06/12/19	2D 3D TSV
US9725446	32	15	HGNC:8816 HGNC:11584 HGNC:14552	7-azaindole derivatives	Merck Patent GmbH	06/12/19	2D 3D TSV
US9725465	406	201	HGNC:6342 HGNC:3765	Biaryl acetamide compounds and methods of use thereof	Ambit Biosciences Corporation	06/12/19	2D 3D TSV
US10189849	50	45	HGNC:1771 HGNC:1773	CDK inhibitors	G1 Therapeutics, Inc.	06/12/19	2D 3D TSV
US10195181	48	38	HGNC:16807	Carboxamide derivatives	Novartis AG	06/12/19	2D 3D TSV
US9725433	164	146	HGNC:3763 HGNC:6307	Compounds as tyrosine kinase modulators	Allergan Inc	06/12/19	2D 3D TSV
US10189853	42	15	HGNC:8803 HGNC:6307 HGNC:3236	Conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as anti-tumor agents	Duquesne University of the Holy Spirit	06/12/19	2D 3D TSV
US9725445	668	296	HGNC:6190 HGNC:6192	Cycloalkyl nitrile pyrazolo pyridones as Janus kinase inhibitors	Merck Sharp & Dohme Corp	06/12/19	2D 3D TSV
US9725426	44	44	HGNC:2501	Cystathionine-γ-lyase (CSE) inhibitors	SOVA PHARMACEUTICALS, INC.	06/12/19	2D 3D TSV
US9725436	51	17		Cytochrome P450 inhibitors and their method of use	CORTENDO AB (PUBL)	06/12/19	2D 3D TSV
US10189859	236	91	HGNC:10597	Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine	Nektar Therapeutics	06/12/19	2D 3D TSV
US10195178	99	98	HGNC:4498	GPR40 agonists in anti-diabetic drug combinations	Janssen Pharmaceutica NV	06/12/19	2D 3D TSV
US10195201	75	32		Heteroaryl-pyrimidinone compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	06/12/19	2D 3D TSV
US9725442	422	338	HGNC:4502	Heterocyclic derivative having PGD2 receptor antagonist activity	Shionogi & Co., Ltd	06/12/19	2D 3D TSV
US9724435	232	99	HGNC:3023 HGNC:11050 HGNC:8156 HGNC:11049	Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders	The University of Mississippi	06/12/19	2D 3D TSV
US9725441	199	93	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	06/12/19	2D 3D TSV
US9725434	62	31	HGNC:4849 HGNC:4848	Hydroxy-substituted orexin receptor antagonists	Merck Sharp & Dohme Corp	06/12/19	2D 3D TSV
US10188639	3	3	HGNC:9236	Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone	DeuteRx, LLC	06/12/19	2D 3D TSV
US10195186	101	49	HGNC:11186	N-substituted-5-substituted phthalamic acids as sortilin inhibitors	H. Lundbeck A/S	06/12/19	2D 3D TSV
US10189791	5	5	HGNC:7873	Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole	Dartmouth College	06/12/19	2D 3D TSV
US9724352	7	7	HGNC:8979	Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	06/12/19	2D 3D TSV
US9725439	29	20	HGNC:3236	Quinazoline derivative and preparation method therefor	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	06/12/19	2D 3D TSV
US9725443	31	31		RORγ modulators	Bristol-Myers Squibb Co.	06/12/19	2D 3D TSV
US9725435	16	16	HGNC:3529	Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors	Bristol-Myers Squibb Co.	06/12/19	2D 3D TSV
US10196346	26	26	HGNC:4910	Substituted acethydrazide derivative, preparation method and use thereof	Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China	06/12/19	2D 3D TSV
US10189854	347	343	HGNC:8781	Substituted pyrimidine compounds	Gruenenthal GmbH	06/12/19	2D 3D TSV
US9725449	371	292		Tricyclic compounds as anticancer agents	Bristol-Myers Squibb Co.	06/12/19	2D 3D TSV
US9725430	18	12	HGNC:3521 HGNC:9642	Use of small molecule inhibitors targeting EYA tyrosine phosphatase	CHILDREN HOSPITAL MEDICAL CENTER	06/12/19	2D 3D TSV
US10189796	9	9	HGNC:6018	[4-(1,3,3-trimethyl-2-oxo-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or salt thereof	Santen Pharmaceutical Co., Ltd	06/12/19	2D 3D TSV
US9663479	6	6	HGNC:1403	γ-aminobutyric acid (GABA) analogues for the treatment of pain and other disorders	Novassay S.A.	06/04/19	2D 3D TSV
US9663475	31	28	HGNC:2529	2 amino-3,4-dihydrcquinazoline derivatives and the use thereof as cathepsin D inhibitors	Merck Patent GmbH	06/04/19	2D 3D TSV
US9663502	580	573		2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation	06/04/19	2D 3D TSV
US9663522	43	40		3-aminocycloalkyl compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	06/04/19	2D 3D TSV
US9663503	18	18	HGNC:1925	5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile and therapeutic uses thereof	Cancer Research Technology Limited	06/04/19	2D 3D TSV
US9663530	136	67		5-oxa-2-azabicyclo[2.2.2]OCTAN-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives	Hoffmann-La Roche Inc	06/04/19	2D 3D TSV
US9663496	493	492	HGNC:9377	AMPK-activating heterocyclic compounds and methods for using the same	Rigel Pharmaceuticals, Inc	06/04/19	2D 3D TSV
US9663526	468	113	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aminopyrimidinyl compounds	Pfizer Inc	06/04/19	2D 3D TSV
US9663498	53	53	HGNC:5301	Aromatic heterocyclic compounds and their application in pharmaceuticals	Sunshine Lake Pharma Co., Ltd	06/04/19	2D 3D TSV
US9663470	177	176	HGNC:5208	Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline	Vitae Pharmaceuticals Inc	06/04/19	2D 3D TSV
US9663523	56	56	HGNC:13575	BET protein-inhibiting 5-aryltriazoleazepines	Bayer Pharma Aktiengesellschaft	06/04/19	2D 3D TSV
US9663508	431	308	HGNC:10593 HGNC:10597	Biaryl acyl-sulfonamide compounds as sodium channel inhibitors	Amgen Inc	06/04/19	2D 3D TSV
US9663519	33	33	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Inc	06/04/19	2D 3D TSV
US9663515	16	16		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals Inc	06/04/19	2D 3D TSV
US9663527	4	4	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	06/04/19	2D 3D TSV
US9663476	18	17	HGNC:11056	Glycine transporter-1 inhibitors	Amgen Inc	06/04/19	2D 3D TSV
US9663494	9	9	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Hoffmann-La Roche Inc	06/04/19	2D 3D TSV
US9663543	33	33	HGNC:2771	Phosphonate compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	06/04/19	2D 3D TSV
US9663525	125	119	HGNC:12477	Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme	Millennium Pharmaceuticals Inc	06/04/19	2D 3D TSV
US9663513	257	224	HGNC:8772	Pyrimidine PDE10 inhibitors	Merck Sharp & Dohme Corp	06/04/19	2D 3D TSV
US9663506	315	292	HGNC:4594	Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use	Merck Sharp & Dohme Corp	06/04/19	2D 3D TSV
US9663511	44	21	HGNC:3169 HGNC:14299	Sphingosine 1-phosphate receptor antagonists	Arroyo BioSciences, LLC	06/04/19	2D 3D TSV
US9663528	23	22	HGNC:10966	Substituted 1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1',2'-d]pyrazines and methods for treating viral infections	Gilead Sciences Inc	06/04/19	2D 3D TSV
US9663510	28	28	HGNC:12401	Substituted triazolopyridines and their use as TTK inhibitors	Bayer Pharma Aktiengesellschaft	06/04/19	2D 3D TSV
US9663529	96	96	HGNC:10252	Tricyclic pyrido-carboxamide derivatives as rock inhibitors	Bristol-Myers Squibb Co.	06/04/19	2D 3D TSV
US9663463	21	21	HGNC:8156	3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purpose	Sanwa Kagaku Kenkyusho Co., Ltd	06/03/19	2D 3D TSV
US9663465	50	26	HGNC:5299 HGNC:108	Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor agonists, their methods of preparation and the pharmaceutical compositions containing the same	UNIVERSITE DE CAEN	06/03/19	2D 3D TSV
US9662330	243	240	HGNC:10436	Aminopyrimidine derivatives for use as modulators of kinase activity	Merck Patent GmbH	06/03/19	2D 3D TSV
US9662339	296	295	HGNC:6710	Benzodioxane inhibitors of leukotriene production for combination therapy	Boehringer Ingelheim International GmbH	06/03/19	2D 3D TSV
US9662310	68	66	HGNC:2300	Cyclopropanecarboxylic acid derivative	Daiichi Sankyo Company, Limited	06/03/19	2D 3D TSV
US9662327	402	393		Phenyl and pyridinyl substituted piperidines and piperazines as inhibitors of IDH1 mutants and their use in treating cancer	Agios Pharmaceuticals Inc	06/03/19	2D 3D TSV
US9663469	319	307		RORγ modulators	Bristol-Myers Squibb Co.	06/03/19	2D 3D TSV
US9663460	209	209	HGNC:1603	Sulfur derivatives as chemokine receptor modulators	Allergan Inc	06/03/19	2D 3D TSV
US10189845	867	207	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors	Array BioPharma Inc	05/29/19	2D 3D TSV
US9636336	248	55	HGNC:1952	Aminoester derivatives	Chiesi Farmaceutici S.p.A.	05/29/19	2D 3D TSV
US9637499	10	10	HGNC:8780	Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors	Leo Pharma A/S	05/29/19	2D 3D TSV
US9637486	28	28	HGNC:1133	Btk inhibitors	Merck Sharp & Dohme Corp	05/29/19	2D 3D TSV
US9637484	20	20	HGNC:17989	Cycloalkyl acid derivative, preparation method thereof, and pharmaceutical application thereof	Shanghai Hengrui Pharmaceutical Co., Ltd	05/29/19	2D 3D TSV
US9636335	44	43	HGNC:5299	Heteroaryl compounds as 5-HT4 receptor ligands	Suven Life Sciences Limited	05/29/19	2D 3D TSV
US9637488	37	33	HGNC:8978	Heterocyclic compounds as inhibitors of class I PI3KS	TBA	05/29/19	2D 3D TSV
US9637455	21	21		Heterocyclic sulfone RORγ modulators	Bristol-Myers Squibb Co.	05/29/19	2D 3D TSV
US9636339	64	32	HGNC:2592 HGNC:2591	Phenyl-dihydropyridine derivatives as aldosterone synthase inhibitors	Hoffman-La Roche Inc	05/29/19	2D 3D TSV
US9636338	48	23	HGNC:2592 HGNC:2591	Phenyl-dihydropyridine derivatives as inhibitors of aldosterone synthase	Hoffmann-La Roche Inc	05/29/19	2D 3D TSV
US9637487	34	34	HGNC:1133	Purinone compounds as kinase inhibitors	Pharmacyclics LLC	05/29/19	2D 3D TSV
US10189841	544	538	HGNC:12607	Purinones as ubiquitin-specific protease 1 inhibitors	Forma Therapeutics Inc	05/29/19	2D 3D TSV
US9636337	315	292	HGNC:4594	Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use	Merck Sharp & Dohme Corp	05/29/19	2D 3D TSV
US9637472	391	389	HGNC:3527	Substituted 6,5-fused bicyclic heteroaryl compounds	Epizyme Inc	05/29/19	2D 3D TSV
US9637496	1033	378	HGNC:4849 HGNC:4848	Substituted 7-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	05/29/19	2D 3D TSV
US9637493	47	45		Substituted pyrrolopyrimidines as HDM2 inhibitors	Merck Sharp & Dohme Corp	05/29/19	2D 3D TSV
US10189840	40	40	HGNC:11892	Substituted tricyclic heterocyclic compounds	Bristol-Myers Squibb Co.	05/29/19	2D 3D TSV
US9636330	15	15	HGNC:3357	Tetrahydrocarboline derivative	Ono Pharmaceutical Co., Ltd	05/29/19	2D 3D TSV
US10189838	117	114		Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection	Hoffman-La Roche Inc	05/26/19	2D 3D TSV
US10189835	22	21		Derivatives and methods of treating hepatitis B infections	NOVIRA THERAPEUTICS, INC.	05/26/19	2D 3D TSV
US10189831	182	181		Non-nucleoside reverse transcriptase inhibitors	Merck Sharp & Dohme Corp	05/26/19	2D 3D TSV
US10189836	398	189	HGNC:6190 HGNC:6192	Therapeutic compounds, compositions and methods of use thereof	Genentech Inc	05/26/19	2D 3D TSV
US10188615	195	171	HGNC:10294 HGNC:9864 HGNC:9866 HGNC:9865 HGNC:10477	Alkoxy compounds for disease treatment	ACUCELA INC.	05/25/19	2D 3D TSV
US10188653	55	55	HGNC:16940	Diacylglycerol acyltransferase 2 inhibitors	Pfizer Inc	05/25/19	2D 3D TSV
US10189819	87	86	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	05/25/19	2D 3D TSV
US10189794	194	192	HGNC:3691	Heteroaryl compounds and uses thereof	Celgene CAR LLC	05/25/19	2D 3D TSV
US10188756	189	27	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853	Imaging histone deacetylases with a radiotracer using positron emission tomography	The General Hospital Corporation	05/25/19	2D 3D TSV
US10189829	145	139	HGNC:1133	Inhibiting agents for Bruton's tyrosine kinase	BIOGEN MA INC.	05/25/19	2D 3D TSV
US10189805	8	8	HGNC:10943	Metabolism probes for therapy and diagnosis	Vanderbilt University	05/25/19	2D 3D TSV
US10188758	8	5	HGNC:11050 HGNC:11048	Organic compounds	Intra-Cellular Therapies Inc	05/25/19	2D 3D TSV
US10188627	67	32	HGNC:9235	PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof	Mitobridge, Inc.	05/25/19	2D 3D TSV
US10188667	22	11	HGNC:4591	Pharmaceutical compositions and methods of use of 4-pregenen-11β-17-21-triol-3,20-dione derivatives	Allergan Inc	05/25/19	2D 3D TSV
US10188642	104	103	HGNC:12401	Pharmacologically active compounds	Cancer Research Technology Limited	05/25/19	2D 3D TSV
US10189809	198	191	HGNC:4685	SGC stimulators	Ironwood Pharmaceuticals, Inc.	05/25/19	2D 3D TSV
US10189788	90	73	HGNC:9600	Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents	Bayer Pharma Aktiengesellschaft	05/25/19	2D 3D TSV
US10189816	194	162		Substituted pyridines as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	05/25/19	2D 3D TSV
US10189807	7	7	HGNC:23	Tetrahydrothiophene-based GABA aminotransferase inactivators	Northwestern University	05/25/19	2D 3D TSV
US9630945	80	80	HGNC:10555	Autotaxin inhibitors	Novartis AG	05/20/19	2D 3D TSV
US9630929	138	57	HGNC:10593 HGNC:10597	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc	05/20/19	2D 3D TSV
US9629836	101	100		Compounds and compositions as inhibitors of MEK	Novartis AG	05/20/19	2D 3D TSV
US9630956	151	149	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Inc	05/20/19	2D 3D TSV
US9630965	73	63	HGNC:5253 HGNC:1735	Fused amino pyridine as HSP90 inhibitors	Curis Inc	05/20/19	2D 3D TSV
US9630914	86	19	HGNC:3553 HGNC:9605	Multitarget FAAH and COX inhibitors and therapeutical uses thereof	Fondazione Istituto Italiano di Tecnologia	05/20/19	2D 3D TSV
US9630949	143	77	HGNC:6932 HGNC:6929	Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics	Galderma Research & Development	05/20/19	2D 3D TSV
US9630931	29	29	HGNC:1925	Pharmaceutically active pyrazine derivatives	Sentinel Oncology Limited	05/20/19	2D 3D TSV
US10183937	838	407	HGNC:15459 HGNC:8534	1,3-thiazol-2-yl substituted benzamides	Bayer Aktiengesellschaft	05/16/19	2D 3D TSV
US10179123	89	74		2-aryl- and 2-arylalkyl-benzimidazoles as mIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	05/16/19	2D 3D TSV
US10174024	77	60	HGNC:13575	5H-pyrido[3,2-B]indole compounds as anticancer agents	Bristol-Myers Squibb Co.	05/16/19	2D 3D TSV
US10174035	234	135	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	6-morpholinyl-2-pyrazolyl-9H-purine derivatives and their use as PI3K inhibitors	Daiichi Sankyo Company, Limited	05/16/19	2D 3D TSV
US10183940	124	78	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amides as somatostatin receptor subtype 4 (SSTR4) agonists	Boehringer Ingelheim International GmbH	05/16/19	2D 3D TSV
US10183025	206	200	HGNC:3357	Autotaxin inhibitors	Novartis AG	05/16/19	2D 3D TSV
US10174049	36	36	HGNC:2843	Compounds as diacylglycerol acyltransferase inhibitors	GlaxoSmithKline	05/16/19	2D 3D TSV
US10179761	52	28	HGNC:8157	Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases	UNIVERSITE DE LILLE 2 DROIT ET SANTE	05/16/19	2D 3D TSV
US10174030	116	116	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	05/16/19	2D 3D TSV
US10174037	579	205		Dihydropyrazolopyrimidinone compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	05/16/19	2D 3D TSV
US10183939	56	21		Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers	Redx Pharma PLC	05/16/19	2D 3D TSV
US10174044	63	62	HGNC:19679	Fused pyridines as kinase inhibitors	Bristol-Myers Squibb Co.	05/16/19	2D 3D TSV
US10183938	448	300	HGNC:5297 HGNC:1960	Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors	Axovant Sciences GmbH	05/16/19	2D 3D TSV
US10174023	22	22	HGNC:270	Heterocyclic-imidazole compounds, pharmaceutical compositions thereof, preparation method therefor and use thereof	SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD	05/16/19	2D 3D TSV
US10174026	297	93	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	05/16/19	2D 3D TSV
US10179769	211	103	HGNC:9886 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	05/16/19	2D 3D TSV
US10183928	8	4	HGNC:9967	Inhibitors of RET	BLUEPRINT MEDICINES CORPORATION	05/16/19	2D 3D TSV
US10179773	10	10		Isoxazole carboxamides as irreversible SMYD inhibitors	Epizyme Inc	05/16/19	2D 3D TSV
US10183942	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	THERAVANCE BIOPHARMA R&D IP, LLC	05/16/19	2D 3D TSV
US10179804	132	132	HGNC:6932	Melanocortin receptor-specific peptides	Palatin Technologies Inc	05/16/19	2D 3D TSV
US10183954	14	14	HGNC:15631	Oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc	05/16/19	2D 3D TSV
US10183913	128	64	HGNC:11050 HGNC:5295	Pyrazole compound	Sumitomo Dainippon Pharma Co., Ltd	05/16/19	2D 3D TSV
US10183947	51	49	HGNC:435	Pyrazole derivatives useful as 5-lipoxygenase activating protein (FLAP) inhibitors	AstraZeneca AB	05/16/19	2D 3D TSV
US10174020	10	10	HGNC:3529	Pyridone or pyrimidone derivative, preparation method therefor and application thereof	SICHUAN HAISCO PHARMACEUTICAL CO., LTD.	05/16/19	2D 3D TSV
US10183944	614	335	HGNC:6192 HGNC:11491	Pyrimido-pyridazinone compounds and methods of use thereof	Asana BioSciences, LLC	05/16/19	2D 3D TSV
US10174040	143	110	HGNC:1373	Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	05/16/19	2D 3D TSV
US10183931	91	36	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation LLC	05/16/19	2D 3D TSV
US10179791	122	42	HGNC:3167 HGNC:3165 HGNC:14299	Spiro-cyclic amine derivatives as S1P modulators	AbbVie B.V.	05/16/19	2D 3D TSV
US10183953	990	258	HGNC:4849 HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	05/16/19	2D 3D TSV
US10183932	357	143	HGNC:3529	Substituted oxopyridine derivatives and use thereof cardiovascular disorders	Bayer Pharma Aktiengesellschaft	05/16/19	2D 3D TSV
US10174028	1162	716	HGNC:9967	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	05/16/19	2D 3D TSV
US10174027	1162	716	HGNC:9967	Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	05/16/19	2D 3D TSV
US10183009	122	121		Therapeutic compounds and uses thereof	Genentech Inc	05/16/19	2D 3D TSV
US10183946	92	45	HGNC:2160 HGNC:2159	Triazolo[4,5-D]pyrimidines	Hoffmann-La Roche Inc	05/16/19	2D 3D TSV
US10183917	18	17	HGNC:7967	Tricyclic compounds and uses thereof in medicine	Sunshine Lake Pharma Co., Ltd	05/16/19	2D 3D TSV
US10183021	388	384	HGNC:4685	sGC stimulators	Ironwood Pharmaceuticals, Inc.	05/16/19	2D 3D TSV
US10174016	873	411	HGNC:2596 HGNC:2637 HGNC:15459 HGNC:2625 HGNC:8534 HGNC:2622 HGNC:2623	1,3-thiazol-2-yl substituted benzamides	BEYER AKTIENGESELLSCHAFT	05/15/19	2D 3D TSV
US9624197	30	15	HGNC:4849 HGNC:4848	2-pyridylamino-4-nitrile-piperidinyl orexin receptor antagonists	Merck Sharp & Dohme Corp	05/15/19	2D 3D TSV
US9624210	3	3	HGNC:11491	Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors	Merck Sharp & Dohme Corp	05/15/19	2D 3D TSV
US10173985	34	18	HGNC:10593 HGNC:10597	Aminoindazole derivatives as sodium channel inhibitors	Almirall, S.A.	05/15/19	2D 3D TSV
US9624159	8	8	HGNC:9596	Aniline derivatives, their preparation and their therapeutic application	Sanofi	05/15/19	2D 3D TSV
US10174013	42	27	HGNC:6251 HGNC:3765	Benzimidazole derivatives as kinase inhibitors	Selvita S.A.	05/15/19	2D 3D TSV
US10174000	62	32	HGNC:17967	Bicyclic-fused heteroaryl or aryl compounds as IRAK4 modulators	Pfizer Inc	05/15/19	2D 3D TSV
US9624235	20	15	HGNC:587	Compounds and methods for inhibition of AP endonuclease-1/redox factor-1 (HAPE1) activity	University of Pittsburgh	05/15/19	2D 3D TSV
US9624213	207	207		Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	05/15/19	2D 3D TSV
US9624217	159	156		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals Inc	05/15/19	2D 3D TSV
US9624175	82	61		Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors	Forma Therapeutics Inc	05/15/19	2D 3D TSV
US9624194	25	22	HGNC:10597	Heteroaryl compounds as sodium channel blockers	Purdue Pharma LP	05/15/19	2D 3D TSV
US9624234	25	24	HGNC:338	Heterocyclic compounds and methods for their use	Novartis AG	05/15/19	2D 3D TSV
US9624243	85	83	HGNC:338	Heterocyclic compounds and methods of their use	Novartis AG	05/15/19	2D 3D TSV
US10174011	307	98	HGNC:3023 HGNC:5286	Heterocyclic compounds, process for preparation of the same and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	05/15/19	2D 3D TSV
US10173996	511	154	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	05/15/19	2D 3D TSV
US10174003	329	106	HGNC:29012 HGNC:13606 HGNC:17071 HGNC:18039 HGNC:20672 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	05/15/19	2D 3D TSV
US9624188	12	12	HGNC:6059	IDO inhibitors	Bristol-Myers Squibb Co.	05/15/19	2D 3D TSV
US9624228	377	370	HGNC:6871	Inhibitors of ERK and methods of use	Kura Oncology Inc	05/15/19	2D 3D TSV
US9624201	20	20	HGNC:1133	Inhibitors of bruton's tyrosine kinase	F. Hoffmann-La Roche Inc	05/15/19	2D 3D TSV
US9623028	67	28	HGNC:2068 HGNC:2069 HGNC:1470 HGNC:12401	Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof	Signal Pharmaceuticals, LLC	05/15/19	2D 3D TSV
US10173988	15	5	HGNC:7889 HGNC:7891 HGNC:2578	N2-(3,4-dimethylphenyl)-6-((4-(p-tolyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamine	GLUCOX BIOTECH AB	05/15/19	2D 3D TSV
US9623021	24	12	HGNC:3467 HGNC:3468	Nuclear receptor binding agents	GTX Inc	05/15/19	2D 3D TSV
US9624247	107	27	HGNC:13575 HGNC:1103 HGNC:2348 HGNC:1104	Pyrazolo-pyrrolidin-4-one derivatives as bet inhibitors and their use in the treatment of disease	Novartis AG	05/15/19	2D 3D TSV
US9624246	30	15	HGNC:17967	Pyridazinone macrocycles as IRAK inhibitors and uses thereof	Merck Patent GmbH	05/15/19	2D 3D TSV
US10173995	7	6	HGNC:8979	Pyridine compounds used as PI3 kinase inhibitors	Teligene Ltd	05/15/19	2D 3D TSV
US9624218	112	32	HGNC:270 HGNC:11941 HGNC:15677	Pyrido[2,3-d]pyrimidin-4-one compounds as tankyrase inhibitors	Eli Lilly and Company	05/15/19	2D 3D TSV
US10174007	40	18		Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors	Pfizer Inc	05/15/19	2D 3D TSV
US9624205	12	6	HGNC:3527	Substituted 6,5-fused bicyclic heteroaryl compounds	Epizyme Inc	05/15/19	2D 3D TSV
US9624199	21	21	HGNC:277	Substituted bipiperidinyl derivatives	Bayer Pharma Aktiengesellschaft	05/15/19	2D 3D TSV
US10174015	92	46	HGNC:3553 HGNC:736	Substituted heterocyclic derivative, preparation method and use thereof	Xiamen University	05/15/19	2D 3D TSV
US9624198	15	14	HGNC:277	Substituted piperidinyltetrahydroquinolines	Bayer Pharma Aktiengesellschaft	05/15/19	2D 3D TSV
US10172868	103	52	HGNC:6307 HGNC:1133 HGNC:6193 HGNC:3689 HGNC:3236 HGNC:3688	Substituted quinazolines for inhibiting kinase activity	NEUPHARMA, INC.	05/15/19	2D 3D TSV
US10173991	590	589	HGNC:6623	Sulfone amide linked benzothiazole inhibitors of endothelial lipase	Bristol-Myers Squibb Co.	05/15/19	2D 3D TSV
US9624241	574	277		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	05/15/19	2D 3D TSV
US10173990	17	17	HGNC:17989	URAT1 inhibitor	Nippon Chemiphar Co., Ltd	05/15/19	2D 3D TSV
US9617246	74	36	HGNC:4849 HGNC:4848	Thioether-piperidinyl orexin receptor antagonists	Merck Sharp & Dohme Corp	05/10/19	2D 3D TSV
US9617225	165	150	HGNC:1780	4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity	VIROSTATICS SRL	05/08/19	2D 3D TSV
US9617262	62	62		Antibacterial cyclopental[C]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones	Janssen Ireland	05/08/19	2D 3D TSV
US9617267	761	86	HGNC:2596 HGNC:9829 HGNC:1097 HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	05/08/19	2D 3D TSV
US9617226	45	44	HGNC:895	Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases	AbbVie Deutschland GmbH & Co. KG	05/08/19	2D 3D TSV
US9617273	122	68	HGNC:270 HGNC:272 HGNC:15677	Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors	BeiGene, Ltd	05/08/19	2D 3D TSV
US9617259	45	45	HGNC:14063	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	05/08/19	2D 3D TSV
US9617242	237	77	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	05/08/19	2D 3D TSV
US9617281	8	8		Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments	LABORATORIES DEL DR. ESTEVE S.A.	05/08/19	2D 3D TSV
US9617260	34	34	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Hoffmann-La Roche Inc	05/08/19	2D 3D TSV
US9617282	218	216	HGNC:17967	Macrocyclic compounds as IRAK4 inhibitors for the treatment of inflammatory diseases	BIOGEN MA INC.	05/08/19	2D 3D TSV
US9617269	97	96	HGNC:8795	N-substituted pyrazolo [3,4-D] pyrimidine ketone compound, and preparation process and use thereof	Sun Yat-sen University	05/08/19	2D 3D TSV
US9617239	89	88	HGNC:4696	Phenoxy thiophene sulfonamides and their use as inhibitors of glucuronidase	North Carolina Central University	05/08/19	2D 3D TSV
US9617250	26	13	HGNC:3167 HGNC:3165	Pyridin-4-yl derivatives	Actelion Pharmaceuticals Ltd	05/08/19	2D 3D TSV
US9617258	611	315	HGNC:6193	Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides	Pfizer Inc	05/08/19	2D 3D TSV
US9617261	11	11	HGNC:6840	Substituted pyridinone compounds as MEK inhibitors	CMG PHARMACEUTICAL CO., LTD.	05/08/19	2D 3D TSV
US9617271	72	72	HGNC:8772	Triazolo compounds	Hoffmann-La Roche Inc	05/08/19	2D 3D TSV
US9617272	20	10	HGNC:11708 HGNC:6059	Tricyclic compounds as inhibitors of immunosuppression mediated by tryptophan metabolization	NewLink Genetics Corporation	05/08/19	2D 3D TSV
US9616063	30	15	HGNC:7218 HGNC:12015	1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase	AstraZeneca AB	05/07/19	2D 3D TSV
US9617222	48	48	HGNC:6307	Alkynyl indazole derivative and use thereof	Senju Pharmaceutical Co., Ltd	05/07/19	2D 3D TSV
US9616064	137	77	HGNC:10251 HGNC:10252	Rho kinase inhibitors and methods of use	H. Lee Moffitt Cancer Center and Research Institute Inc	05/07/19	2D 3D TSV
US9616059	12	4	HGNC:5465 HGNC:11393 HGNC:427	Substituted indazole derivatives active as kinase inhibitors	Nerviano Medical Sciences srl	05/07/19	2D 3D TSV
US10172856	122	122	HGNC:17383	2,4-diaminopyrimidine derivatives as histamine H4 modulators	Janssen Pharmaceutica NV	04/30/19	2D 3D TSV
US10172859	919	330	HGNC:6251 HGNC:9413	Arylquinazolines	Merck Patent GmbH	04/30/19	2D 3D TSV
US9611269	84	42	HGNC:6190 HGNC:6192	Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors	Incyte Corporation	04/30/19	2D 3D TSV
US10172858	368	95	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:3942 HGNC:8977	Combination pharmaceutical compositions and uses thereof	Intellikine LLC	04/30/19	2D 3D TSV
US9611270	21	14	HGNC:2593 HGNC:2600	Inhibitors of CYP17A1	University of Kansas	04/30/19	2D 3D TSV
US10172837	11	11	HGNC:1368	Insulin sensitisers and methods of treatment	Naia Metabolic, Inc.	04/30/19	2D 3D TSV
US9611275	61	59	HGNC:7056	Permeable glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	04/30/19	2D 3D TSV
US10172843	81	79	HGNC:2545	Piperidine derivatives	Hoffmann-La Roche Inc	04/30/19	2D 3D TSV
US9611277	990	259	HGNC:4849 HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	04/30/19	2D 3D TSV
US10172845	2116	814		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	04/30/19	2D 3D TSV
US10172851	1229	556		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	04/30/19	2D 3D TSV
US10172814	213	157	HGNC:9605	Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and medical uses thereof	Bayer Pharma Aktiengesellschaft	04/30/19	2D 3D TSV
US10172864	1070	389		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals Inc	04/30/19	2D 3D TSV
US9611229	39	39		1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders	LABORATORIOS DEL DR. ESTEVE S.A.	04/29/19	2D 3D TSV
US9611249	35	34	HGNC:4617	1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors	AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.	04/29/19	2D 3D TSV
US9611224	350	177	HGNC:590 HGNC:591	Antiproliferative benzo [B] azepin-2-ones	Hoffmann-La Roche Inc	04/29/19	2D 3D TSV
US9610264	16	15	HGNC:6162	Compounds for the treatment and prevention of retroviral infections	KFLP BIOTECH, LLC	04/29/19	2D 3D TSV
US9610299	42	12	HGNC:6833 HGNC:6834 HGNC:404	Compounds for the treatment of addiction	Gilead Sciences Inc	04/29/19	2D 3D TSV
US9611221	199	93	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	04/29/19	2D 3D TSV
US9610322	10	10	HGNC:5381	Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof	President and Fellows of Harvard College	04/29/19	2D 3D TSV
US9611232	8	8	HGNC:6293	Oxazolidinone and imidazolidinone compounds	Hoffmann-La Roche Inc	04/29/19	2D 3D TSV
US9611261	846	397	HGNC:2529 HGNC:933	Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use	Amgen Inc	04/29/19	2D 3D TSV
US9611222	152	151	HGNC:10597	Pyridine compounds and the uses thereof	Purdue Pharma LP	04/29/19	2D 3D TSV
US9611262	489	129	HGNC:4849 HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	04/29/19	2D 3D TSV
US9611251	546	192	HGNC:4849 HGNC:4848	Substituted piperidine compounds and their use as orexin receptor modulators	Janssen Pharmaceutica NV	04/29/19	2D 3D TSV
US9611259	3	3		Substituted pyridine derivatives useful as C-FMS kinase inhibitors	Janssen Pharmaceutica NV	04/29/19	2D 3D TSV
US9611267	699	232	HGNC:3690 HGNC:3689 HGNC:3688	Substituted tricyclic compounds as FGFR inhibitors	Incyte Holdings Corporation	04/29/19	2D 3D TSV
US9611252	146	145	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	04/29/19	2D 3D TSV
US9611265	241	79	HGNC:8031 HGNC:8032 HGNC:8033	Tropomyosin-related kinase (TRK) inhibitors	Genzyme Corporation	04/29/19	2D 3D TSV
US10167299	125	111	HGNC:1606 HGNC:6251	1-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	04/24/19	2D 3D TSV
US10167282	14	5	HGNC:6251	1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer	Cancer Research Technology Limited	04/24/19	2D 3D TSV
US9605007	135	118	HGNC:6251 HGNC:933 HGNC:2625	2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides	Pfizer Inc	04/24/19	2D 3D TSV
US10167261	20	9		2-oxo-3,4-dihydroquinolin-6-yl sulphonamide CPDS and their use as plant growth regulators	University of California	04/24/19	2D 3D TSV
US9605006	15	15	HGNC:933	5-aryl-1-imino-1-oxo-[1,2,4]thiadiazines	Hoffmann-La Roche Inc	04/24/19	2D 3D TSV
US9605005	199	198	HGNC:5960	Alkynyl alcohols and methods of use	Genentech Inc	04/24/19	2D 3D TSV
US10167292	172	37		Benzodiazepines as bromodomain inhibitors	Catalyst Therapeutics Pty Ltd.	04/24/19	2D 3D TSV
US9605008	21	21	HGNC:8784	Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof	Bayer Pharma Aktiengesellschaft	04/24/19	2D 3D TSV
US10167279	409	305	HGNC:9829	Compounds and compositions as RAF kinase inhibitors	Novartis AG	04/24/19	2D 3D TSV
US10167276	207	69		Compounds and methods for inhibiting JAK	Dizal (Jiangsu) Pharmaceutical Co., Ltd.	04/24/19	2D 3D TSV
US9604998	109	95	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	04/24/19	2D 3D TSV
US9605022	39	20	HGNC:592	Macrocyclic compounds for inhibition of inhibitors of apoptosis	Ensemble Therapeutics Corp	04/24/19	2D 3D TSV
US9605024	9	9	HGNC:3540	PAR4 agonist peptides	Bristol-Myers Squibb Co.	04/24/19	2D 3D TSV
US10167256	8	4	HGNC:3023	Psychotrophic agents and uses thereof	LB PHARMACEUTICALS INC.	04/24/19	2D 3D TSV
US10167313	102	25	HGNC:1506 HGNC:1508 HGNC:1504 HGNC:1499 HGNC:1511	Selective caspase inhibitors and uses thereof	Genesis Technologies Limited	04/24/19	2D 3D TSV
US10167285	48	16	HGNC:3430 HGNC:5253	Small-molecule HSP90 inhibitors	Memorial Sloan-Kettering Cancer Center	04/24/19	2D 3D TSV
US10166249	952	228	HGNC:3167 HGNC:10817	Substituted bicyclic compounds	Bristol-Myers Squibb Co.	04/24/19	2D 3D TSV
US10167280	108	47	HGNC:3529	Substituted oxopyridine derivatives	Bayer Pharma Aktiengesellschaft	04/24/19	2D 3D TSV
US10167264	10	5	HGNC:3236	Substituted pyrimidines useful as EGFR-T790M kinase inhibitors	Jiangsu Medolution Ltd	04/24/19	2D 3D TSV
US10167270	175	127	HGNC:4177	Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity	Northwestern University	04/24/19	2D 3D TSV
US10167281	213	119	HGNC:8537	Substituted thiazole or oxazole P2X7 receptor antagonists	Axxam S.P.A.	04/24/19	2D 3D TSV
US10166216	151	151		Substituted triazoles useful as Axl inhibitors	Rigel Pharmaceuticals, Inc	04/24/19	2D 3D TSV
US10167273	111	107		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases	Takeda Pharmaceutical Co., Ltd	04/24/19	2D 3D TSV
US10167296	99	67	HGNC:7110 HGNC:7111	Sulfoximine substituted quinazolines for pharmaceutical compositions	EVOTEC INTERNATIONAL GMBH	04/24/19	2D 3D TSV
US10166239	241	78	HGNC:8031 HGNC:8032 HGNC:8033	Tropomyosin-related kinase (Trk) inhibitors	Genzyme Corporation	04/24/19	2D 3D TSV
US10167293	76	76	HGNC:386	[8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones	Bayer Pharma Aktiengesellschaft	04/24/19	2D 3D TSV
US9603834	27	26	HGNC:1603	1,2- bis-sulfonamide derivatives as chemokine receptor modulators	Allergan Inc	04/23/19	2D 3D TSV
US9604984	934	465	HGNC:6190 HGNC:6192	5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof	Genentech Inc	04/23/19	2D 3D TSV
US9604960	81	27	HGNC:11050 HGNC:11048 HGNC:11049	Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof	Albany Molecular Research, Inc.	04/23/19	2D 3D TSV
US9604944	6	2	HGNC:5286	Arylpiperazine derivatives and methods of utilizing same	Reviva Pharmaceuticals Inc	04/23/19	2D 3D TSV
US9603833	88	42	HGNC:6833 HGNC:6834 HGNC:550	Benzene or thiophene derivative and use thereof as VAP-1 inhibitor	R-Tech Ueno, Ltd.	04/23/19	2D 3D TSV
US9604977	516	251	HGNC:3560 HGNC:3559	Bicyclic thiophenylamide compounds	Hoffman-La Roche Inc	04/23/19	2D 3D TSV
US9604926	226	99	HGNC:3023 HGNC:4584 HGNC:11050 HGNC:8156 HGNC:11048 HGNC:11049	Highly selective sigma receptor radioligands	The University of Mississippi	04/23/19	2D 3D TSV
US9604961	509	153	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	04/23/19	2D 3D TSV
US9603889	86	43	HGNC:592	IAP antagonists	Bristol-Myers Squibb Co.	04/23/19	2D 3D TSV
US9604989	159	80	HGNC:391 HGNC:392	Imidazopyridazines as Akt kinase inhibitors	Bayer Intellectual Property GmbH	04/23/19	2D 3D TSV
US9603854	119	113	HGNC:990	Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	04/23/19	2D 3D TSV
US9604931	24	12	HGNC:3473 HGNC:3471	Nuclear receptor binding agents	GTX Inc	04/23/19	2D 3D TSV
US9604982	678	116	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	04/23/19	2D 3D TSV
US9603836	28	27	HGNC:6059	Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors	iTeos Therapeutics	04/23/19	2D 3D TSV
US9603819	13	13	HGNC:7154	Substituted aminobutyric derivatives as neprilysin inhibitors	Novartis AG	04/23/19	2D 3D TSV
US9604945	7	7	HGNC:11049	Sydnonimines-specific dopamine reuptake inhibitors and their use in treating dopamine related disorders	Caliper Life Sciences, Inc.	04/23/19	2D 3D TSV
US10166226	9	9		CGRP receptor antagonists	Heptares Therapeutics Limited	04/11/19	2D 3D TSV
US10166229	10	10	HGNC:1504	Compounds and methods for the treatment of cancer	University of Illinois	04/11/19	2D 3D TSV
US10155763	7	7		2-pyridyl substituted imidazoles as ALK5 and/or ALK4 inhibitors	TIUMBIO CO., LTD.	04/10/19	2D 3D TSV
US10155750	76	38	HGNC:4849 HGNC:4848	Amidoethyl azole orexin receptor antagonists	Merck Sharp & Dohme Corp	04/10/19	2D 3D TSV
US10155760	237	233	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Co.	04/10/19	2D 3D TSV
US10155765	66	66	HGNC:17967	Carboxamide inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	04/10/19	2D 3D TSV
US10155769	91	91	HGNC:1406	Fused azaheterocyclic compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	04/10/19	2D 3D TSV
US10155768	520	197	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	04/10/19	2D 3D TSV
US10155752	16	12	HGNC:10597	Indazoles and use thereof	Purdue Pharma LP	04/10/19	2D 3D TSV
US10155733	27	27	HGNC:1952	N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same	Conopco, Inc.	04/10/19	2D 3D TSV
US10155731	131	127	HGNC:9958	Nitrogen-containing saturated heterocyclic compound	Mitsubishi Tanabe Pharma Corporation	04/10/19	2D 3D TSV
US10155751	81	27		Pyrazolyl-substituted heteroaryls and their use as medicaments	Boehringer Ingelheim International GmbH	04/10/19	2D 3D TSV
US10155732	5	5	HGNC:10452	Ribonucleotide reductase inhibitors and methods of use	City of Hope	04/10/19	2D 3D TSV
US10155972	10	6	HGNC:11708	Screening method	Iomet Pharma Ltd.	04/10/19	2D 3D TSV
US10166214	284	169	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin receptor subtype 4 (SSTR4) agonists	Centrexion Therapeutics Corporation	04/10/19	2D 3D TSV
US10155775	8	8	HGNC:3009	Substituted amino six-membered saturated heteroalicycles as long-acting DPP-IV inhibitors	Centaurus BioPharma Co., Ltd	04/10/19	2D 3D TSV
US10155764	114	111		Therapeutic compounds and uses thereof	Genentech Inc	04/10/19	2D 3D TSV
US10150759	3	3	HGNC:3527	1,4-pyridone bicycic heteroaryl compounds	Epizyme Inc	04/09/19	2D 3D TSV
US10150755	127	89	HGNC:6857 HGNC:7590 HGNC:11892	ASK1 inhibitor compounds and uses thereof	SEAL ROCK THERAPEUTICS, INC.	04/09/19	2D 3D TSV
US9657003	40	20		Androgen receptor modulating compounds	ORION CORPORATION	04/09/19	2D 3D TSV
US10155722	20	20	HGNC:5383	Antitumor compound targeting IDH2 mutation and method of use thereof	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	04/09/19	2D 3D TSV
US10155002	334	185	HGNC:3527	Aryl- or heteroaryl-substituted benzene compounds	Epizyme Inc	04/09/19	2D 3D TSV
US9657001	65	65	HGNC:6719	Compounds and uses	AstraZeneca AB	04/09/19	2D 3D TSV
US10150760	390	224	HGNC:339	Compounds for use in preparing heterocyclic triazole agonists of the APJ receptor	Amgen Inc	04/09/19	2D 3D TSV
US9656996	17	17	HGNC:11892	Fused heterocyclic compound, preparation method therefor, pharmaceutical composition, and uses thereof	Shanghai Yingli Pharmaceutical Co., Ltd	04/09/19	2D 3D TSV
US9657009	168	150	HGNC:17967	Heteroaryl substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Co.	04/09/19	2D 3D TSV
US10150763	76	38	HGNC:4852 HGNC:14064	Histone deacetylase inhibitors and their use in therapy	Karus Therapeutics Limited	04/09/19	2D 3D TSV
US9656988	1351	352	HGNC:1133 HGNC:6193 HGNC:3236 HGNC:6524	Inhibitors of Bruton's tyrosine kinase	Pharmacyclics LLC	04/09/19	2D 3D TSV
US9656991	121	70	HGNC:9753	Inhibitors of glutaminyl cyclase	Probiodrug AG	04/09/19	2D 3D TSV
US10150765	843	286	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	04/09/19	2D 3D TSV
US10150766	102	62	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	04/09/19	2D 3D TSV
US10150758	30	29	HGNC:10894	PRMT5 inhibitors and uses thereof	Epizyme Inc	04/09/19	2D 3D TSV
US10155727	217	103	HGNC:4586 HGNC:6251	Pyrazoles	JANSSEN PHARMACEUTICALS, INC.	04/09/19	2D 3D TSV
US9657007	36	18	HGNC:8979 HGNC:8978 HGNC:8977 HGNC:8976	Substituted aminopyrimidine compounds and methods of use	CALITOR SCIENCES, LLC	04/09/19	2D 3D TSV
US10150764	139	70	HGNC:3527	Substituted benzene compounds	Epizyme Inc	04/09/19	2D 3D TSV
US9657015	73	49	HGNC:3309	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	04/09/19	2D 3D TSV
US10150787	10	10	HGNC:9650	TC-PTP inhibitors as APC activators for immunotherapy	TBA	04/09/19	2D 3D TSV
US9657033	112	92		Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORγ activity and the treatment of disease	Lycera Corporation	04/09/19	2D 3D TSV
US10150767	46	45		Therapeutic compounds and uses thereof	Genentech Inc	04/09/19	2D 3D TSV
US10150762	178	86		Trifluoromethyl alcohols as modulators of RORγt	Janssen Pharmaceutica NV	04/09/19	2D 3D TSV
US9656975	20	10	HGNC:4579	Bicyclo[3.2.1]octyl amide derivatives and uses of same	H. Lundbeck A/S	04/08/19	2D 3D TSV
US9655879	188	94	HGNC:9490 HGNC:9475	Heteroarylcarboxylic acid ester derivative	EA Pharma Co., Ltd.	04/08/19	2D 3D TSV
US9656961	158	54	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	04/08/19	2D 3D TSV
US9656968	122	102	HGNC:10597	Pyrimidines as sodium channel blockers	TBA	04/08/19	2D 3D TSV
US9656955	808	790	HGNC:7044	Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Inc	04/08/19	2D 3D TSV
US9656962	87	47	HGNC:8153 HGNC:8154 HGNC:8155 HGNC:8156	Ring-contracted morphinans and the use thereof	Purdue Pharma LP	04/08/19	2D 3D TSV
US9656959	90	77	HGNC:10597	Substituted pyridines as sodium channel blockers	Purdue Pharma LP	04/08/19	2D 3D TSV
US9649308	246	175	HGNC:8537	Benzamide-containing compounds and their use in the treatment of pain	H. Lundbeck A/S	04/03/19	2D 3D TSV
US9650377	368	161	HGNC:4597 HGNC:4593	Diazepinone derivatives	Novartis AG	04/03/19	2D 3D TSV
US9650366	16	13	HGNC:6307 HGNC:8804 HGNC:9437	Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors	Allergan Inc	04/03/19	2D 3D TSV
US9650362	20	10	HGNC:9753	Inhibitors	Probiodrug AG	04/03/19	2D 3D TSV
US9650336	11	11		Mono-fluoro beta-secretase inhibitors	AstraZeneca AB	04/03/19	2D 3D TSV
US9650358	339	335	HGNC:1780	Pyridine CDK9 kinase inhibitors	AbbVie Inc	04/03/19	2D 3D TSV
US9650371	37	37	HGNC:933	Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity	Shionogi & Co., Ltd	04/03/19	2D 3D TSV
US9649309	1394	400	HGNC:7027 HGNC:12446 HGNC:3765	Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity	University of North Carolina at Chapel Hill	04/03/19	2D 3D TSV
US10150740	15	15		6,7-dihydropyrido[2,1-A]phthalazin-2-ones for the treatment and prophylaxis of hepatitis B virus infection	Hoffmann-La Roche Inc	03/31/19	2D 3D TSV
US10150728	704	701	HGNC:85	Alkylene derivatives	Shionogi & Co., Ltd	03/31/19	2D 3D TSV
US10144746	350	344	HGNC:6371	Bridged bicyclic kallikrein inhibitors	Global Blood Therapeutics, Inc.	03/31/19	2D 3D TSV
US10150743	28	13	HGNC:15631 HGNC:15632	Carboxylic acid compounds	Sumitomo Dainippon Pharma Co., Ltd	03/31/19	2D 3D TSV
US10149839	156	72	HGNC:3467	Chemical compounds	AstraZeneca AB	03/31/19	2D 3D TSV
US10149841	6	6	HGNC:1232	Compound of 3-hydroxyl pyridine, preparation method thereof and pharmaceutical use thereof	SHENYANG SUNSHINE PHARMACEUTICAL CO. LTD.	03/31/19	2D 3D TSV
US10150747	65	31		Compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	03/31/19	2D 3D TSV
US10149835	7	7	HGNC:7967	Isoxazole derivatives as FXR agonists and methods of use thereof	Elmore Patent Law Group, P.C.	03/31/19	2D 3D TSV
US10149840	3	3	HGNC:9221	OCT3 activity inhibitor containing imidazopyridine derivative as active component, and OCT3 detection agent	SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.	03/31/19	2D 3D TSV
US10150751	82	41	HGNC:4849 HGNC:4848	Pyrrolidine orexin receptor antagonists	Merck Sharp & Dohme Corp	03/31/19	2D 3D TSV
US10143681	183	71	HGNC:6371 HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	03/30/19	2D 3D TSV
US10138245	14	14	HGNC:8772	Fused triazole derivatives as phosphodiesterase 10A inhibitors	Celon Pharma S.A.	03/30/19	2D 3D TSV
US10143668	5	5	HGNC:4879	Hydroxy-substituted amino and ammonium derivatives and their medical use	GRI BIO, INC.	03/30/19	2D 3D TSV
US10138253	38	28		Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	03/30/19	2D 3D TSV
US10143746	28	28		Immunomodulators	Bristol-Myers Squibb Co.	03/30/19	2D 3D TSV
US10144729	8	8	HGNC:7967	Isoxazole analogs as FXR agonists and methods of use thereof	Enanta Pharmaceuticals Inc	03/30/19	2D 3D TSV
US10143704	1	1		Methods for treating cancer	Epizyme Inc	03/30/19	2D 3D TSV
USRE47141	78	78		Methods of treating fibrosis, cancer and vascular injuries	EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION	03/30/19	2D 3D TSV
US10144731	519	257	HGNC:7782	Nrf2 regulators	GlaxoSmithKline	03/30/19	2D 3D TSV
US10144715	925	407	HGNC:7966 HGNC:7965	Piperazine derivatives as liver X receptor modulators	Vitae Pharmaceuticals Inc	03/30/19	2D 3D TSV
US10144738	148	35	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolo[1,5-A]PYRAZIN-4-YL derivatives	Pfizer Inc	03/30/19	2D 3D TSV
US10138242	229	112	HGNC:8856	Pyrazolopyridine derivatives and their use in therapy	TBA	03/30/19	2D 3D TSV
US10143695	130	26	HGNC:3430	Pyrrolobenzodiazepines and conjugates thereof	Mersana Therapeutics, Inc.	03/30/19	2D 3D TSV
US10144742	520	520	HGNC:30092	Quinoxaline compounds and uses thereof	Millennium Pharmaceuticals Inc	03/30/19	2D 3D TSV
US10144734	2116	812	HGNC:9967	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	03/30/19	2D 3D TSV
US10138249	20	20	HGNC:29079	Triazolopyridines and triazolopyrazines as LSD1 inhibitors	Incyte Corporation	03/30/19	2D 3D TSV
US10137110	81	46		1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors	Bayer Pharma Aktiengesellschaft	03/29/19	2D 3D TSV
US9597318	7	7	HGNC:9035	2-oxothiazole compounds and method of using same for chronic inflammatory disorders	Avexxin AS	03/29/19	2D 3D TSV
US9598446	65	65	HGNC:2771	Amino compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	03/29/19	2D 3D TSV
US10138212	111	111	HGNC:263	Aminoquinazoline compounds as A2A antagonist	Merck Sharp & Dohme Corp	03/29/19	2D 3D TSV
US9598407	41	41		Antibacterial piperidinyl substituted 3,4-dihydro-1H-[1,8]naphthyridinones	Janssen Ireland	03/29/19	2D 3D TSV
US10137202	11	6	HGNC:3590	Antibody-drug conjugates and immunotoxins	Oncomatryx Biopharma, S.L.	03/29/19	2D 3D TSV
US10138230	125	123	HGNC:3357	Autotaxin inhibitors	Cancer Research Technology Limited	03/29/19	2D 3D TSV
US9597333	160	79	HGNC:15631 HGNC:15632	Benzazepine dicarboxamide compounds	Hoffmann-La Roche Inc	03/29/19	2D 3D TSV
US10138226	44	35		Benzimidazol-2-amines as MIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	03/29/19	2D 3D TSV
US9597326	26	26	HGNC:15631	Benzonapthyridine compositions and uses thereof	GlaxoSmithKline	03/29/19	2D 3D TSV
US10131670	108	36	HGNC:1884	Bicyclic heteroaryl derivatives as CFTR potentiators	CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC.	03/29/19	2D 3D TSV
US10131663	194	70	HGNC:6251 HGNC:3467	Chemical compounds	AstraZeneca AB	03/29/19	2D 3D TSV
US9598415	265	261		Compounds as modulators of RORγ	Boehringer Ingelheim International GmbH	03/29/19	2D 3D TSV
US9598431	15	4	HGNC:10259 HGNC:10258	Compounds useful for inhibiting ROR-gamma-t	Eli Lilly and Company	03/29/19	2D 3D TSV
US10138240	2	2		Crystal of 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative	Daiichi Sankyo Company, Limited	03/29/19	2D 3D TSV
US9597330	60	48	HGNC:10597	Drugs for treating respiratory diseases	Daiichi Sankyo Company, Limited	03/29/19	2D 3D TSV
US10138236	66	33	HGNC:6371 HGNC:3529	Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives	Bayer Pharma Aktiengesellschaft	03/29/19	2D 3D TSV
US10138229	156	149	HGNC:1133	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	03/29/19	2D 3D TSV
US9598421	372	103	HGNC:8780 HGNC:8781 HGNC:8783	Imidazopyridazine compounds	Pfizer Inc	03/29/19	2D 3D TSV
US9597310	65	65	HGNC:4498	Indanyloxydihydrobenzofuranylacetic acids	Boehringer Ingelheim International GmbH	03/29/19	2D 3D TSV
US9598440	159	158	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	03/29/19	2D 3D TSV
US10131664	178	174	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	03/29/19	2D 3D TSV
US10138228	4	4	HGNC:7967	Isoxazole derivatives as FXR agonists and methods of use therof	Enanta Pharmaceuticals Inc	03/29/19	2D 3D TSV
US10137122	244	116	HGNC:2452 HGNC:4617 HGNC:4616	Kinase inhibitors and methods of use thereof	The Broad Institute, Inc.	03/29/19	2D 3D TSV
US9598426	8	4	HGNC:8775 HGNC:8774	Organic compounds	Intra-Cellular Therapies Inc	03/29/19	2D 3D TSV
US9598447	72	14	HGNC:8153 HGNC:8154 HGNC:8155 HGNC:8156	Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof	Purdue Pharma LP	03/29/19	2D 3D TSV
US10131673	42	41		Piperidine substituted tricyclic pyrazolo[1,5-a]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)	Janssen Ireland	03/29/19	2D 3D TSV
US9598370	55	24	HGNC:1232 HGNC:12680 HGNC:14661	Prolyl hydroxylase inhibitors and methods of use	Akebia Therapeutics, Inc.	03/29/19	2D 3D TSV
US9598381	18	17	HGNC:20982	SMYD2 inhibitors	AbbVie Inc	03/29/19	2D 3D TSV
US9598410	68	64	HGNC:6278	Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-C]pyridines, their use as medicament, and pharmaceutical preparations comprising them	Sanofi	03/29/19	2D 3D TSV
US9598423	827	421	HGNC:2453 HGNC:2452	Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors	Bristol-Myers Squibb Co.	03/29/19	2D 3D TSV
US10138222	122	120	HGNC:10020	Substituted benzamides as RIPK2 inhibitors	Boehringer Ingelheim International GmbH	03/29/19	2D 3D TSV
US10138241	97	97	HGNC:10020	Substituted benzamides as RIPK2 inhibitors	Boehringer Ingelheim International GmbH	03/29/19	2D 3D TSV
US9598411	172	73	HGNC:8153 HGNC:8154 HGNC:8155 HGNC:8156	Substituted benzimidazole-type piperidine compounds and uses thereof	Purdue Pharma LP	03/29/19	2D 3D TSV
US9598416	159	83	HGNC:3690 HGNC:3688	Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer	Bayer Intellectual Property GmbH	03/29/19	2D 3D TSV
US9598436	18	18	HGNC:2593	Substituted bicyclic heteroaryl compounds	Bristol-Myers Squibb Co.	03/29/19	2D 3D TSV
US9598401	63	46	HGNC:5286	Substituted heteroaryl compounds and methods of use thereof	Sunshine Lake Pharma Co., Ltd	03/29/19	2D 3D TSV
US9597317	74	37	HGNC:6342 HGNC:3765	Substituted indazole derivatives active as kinase inhibitiors	Nerviano Medical Sciences srl	03/29/19	2D 3D TSV
US10137124	1229	557	HGNC:9967	Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	03/29/19	2D 3D TSV
US10131667	699	231	HGNC:3690 HGNC:3689 HGNC:3688	Substituted tricyclic compounds as FGFR inhibitors	Incyte Corporation	03/29/19	2D 3D TSV
US9598396	39	19	HGNC:270 HGNC:15677	Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors	Janssen Pharmaceutica NV	03/29/19	2D 3D TSV
US9598405	52	44	HGNC:11491	Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors	Merck Sharp & Dohme Corp	03/29/19	2D 3D TSV
US10137210	9	9	HGNC:620	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition	The University of Pittsburgh—Of the Commonwealth System of Higher Education	03/29/19	2D 3D TSV
US10131675	153	152	HGNC:6851	Tricyclic DLK inhibitors and uses thereof	Genentech Inc	03/29/19	2D 3D TSV
US9598387	260	129	HGNC:3023 HGNC:3024	Urea and amide derivatives of aminoalkylpiperazines and use thereof	Southern Research Institute	03/29/19	2D 3D TSV
US10131692	88	43	HGNC:897 HGNC:896	Vasopressin-2 receptor agonists	Ferring B.V.	03/29/19	2D 3D TSV
US10130619	70	70	HGNC:7889	Amido thiadiazole derivatives as NADPH oxidase inhibitors	GENKYOTEX SUISSE SA	03/28/19	2D 3D TSV
US10131658	37	34	HGNC:6141	Anti-alphavbeta1 integrin compounds and methods	The Regents of the University of California	03/28/19	2D 3D TSV
US10131645	33	33		Benzofurans substituted with primary benzamide as HCV inhibitors	Bristol-Myers Squibb Co.	03/28/19	2D 3D TSV
US10130617	18	9	HGNC:3467	Chemical compounds	AstraZeneca AB	03/28/19	2D 3D TSV
US10130633	700	254	HGNC:15983	Compounds	Bayer Pharma Aktiengesellschaft	03/28/19	2D 3D TSV
US10130622	11	4	HGNC:1884	Compounds for treatment of cystic fibrosis	AbbVie S.á.r.l.	03/28/19	2D 3D TSV
US10130642	65	64	HGNC:7154	Neprilysin inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	03/28/19	2D 3D TSV
US10131648	98	97	HGNC:4498	Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes	Janssen Pharmaceutica NV	03/28/19	2D 3D TSV
US10131651	13	9	HGNC:4498	[7,6]-fused bicyclic antidiabetic compounds	Merck Sharp & Dohme Corp	03/28/19	2D 3D TSV
US9593097	435	405		Axl inhibitors	Pfizer Inc	03/15/19	2D 3D TSV
US9593099	22	22	HGNC:1097	Compounds and compositions as protein kinase inhibitors	Array BioPharma Inc	03/15/19	2D 3D TSV
US9593100	23	23	HGNC:1097	Compounds and compositions as protein kinase inhibitors	Array BioPharma Inc	03/15/19	2D 3D TSV
US9593127	20	20	HGNC:4597	Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptors	RECORDATI IRELAND LTD.	03/15/19	2D 3D TSV
US9593123	194	97	HGNC:2160 HGNC:2159	Triazolo[4,5-D]pyrimidine derivatives	Hoffmann-La Roche Inc	03/15/19	2D 3D TSV
US9592235	219	214	HGNC:6866	Aminoquinazoline and pyridopyrimidine derivatives	Genentech Inc	03/14/19	2D 3D TSV
US9593105	223	144	HGNC:8537	Cyclic amines	H. Lundbeck A/S	03/14/19	2D 3D TSV
US9593110	201	168	HGNC:7154	Neprilysin inhibitors	Theravence Biopharma R&D IP, LLC	03/14/19	2D 3D TSV
US9592230	125	125	HGNC:8772	Substituted imidazoles as PDE10A inhibitors	H. Lundbeck A/S	03/14/19	2D 3D TSV
US10125145	31	29	HGNC:5297	5-HT3 receptor antagonists	Takeda Pharmaceutical Co., Ltd	03/12/19	2D 3D TSV
US10125150	26	26	HGNC:6190	Crystalline forms of a PI3K inhibitor	Incyte Corporation	03/12/19	2D 3D TSV
US9593113	85	83	HGNC:7978	Imide and acylurea derivatives as modulators of the glucocorticoid receptor	Bristol-Myers Squibb Co.	03/12/19	2D 3D TSV
US9593121	14	14	HGNC:25581	Indole substituted pyrrolopyrimidinyl inhibitors of Uba6	Millennium Pharmaceuticals Inc	03/12/19	2D 3D TSV
US9593129	497	406		Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer	Amgen Inc	03/12/19	2D 3D TSV
US10125148	28	27		Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	03/12/19	2D 3D TSV
US10125097	18	18	HGNC:9358	1- [1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives	Universitat de Barcelona	03/11/19	2D 3D TSV
US10125111	99	97		Benzofuran compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	03/11/19	2D 3D TSV
US10125137	10	10		Benzofurans substituted with bicyclic secondary benzamide as HCV inhibitors	Bristol-Myers Squibb Co.	03/11/19	2D 3D TSV
US10124009	14	7	HGNC:13575	Bromodomain inhibitors	Tensha Therapeutics, Inc.	03/11/19	2D 3D TSV
US10125135	51	47	HGNC:3467	Chemical compounds	AstraZeneca AB	03/11/19	2D 3D TSV
US10123995	32	20	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	03/11/19	2D 3D TSV
US10125118	458	450	HGNC:7027	Heteroaryl compounds and their use as therapeutic drugs	Dong-A Socio Holdings Co., Ltd.	03/11/19	2D 3D TSV
US10117875	20	20	HGNC:15633	Immune system modulators	JANUS BIOTHERAPEUTICS, INC.	03/11/19	2D 3D TSV
US10125101	123	45	HGNC:4498 HGNC:2622 HGNC:2623	Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	03/11/19	2D 3D TSV
US10112968	7	7		Inhibitors of protein methyltransferase DOT1L and methods of use thereof	Epizyme Inc	03/11/19	2D 3D TSV
US10112955	73	53	HGNC:7110 HGNC:7111	Isoindoline, azaisoindoline, dihydroindenone and dihydroazaindenone inhibitors of Mnk1 and Mnk2	eFFECTOR Therapeutics Inc	03/11/19	2D 3D TSV
US10118894	7	7		Isoindolinone derivatives useful as antiviral agents	ViiV HEALTHCARE UK LIMITED	03/11/19	2D 3D TSV
US10118915	563	548	HGNC:8154	Kappa opioid ligands	The Scripps Research Institute	03/11/19	2D 3D TSV
US10125100	197	73	HGNC:11491 HGNC:11283 HGNC:6251 HGNC:4616 HGNC:6876	Kinase inhibitors	Topivert Pharma Limited	03/11/19	2D 3D TSV
US10125125	58	58	HGNC:10499	N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors	Active Biotech AB	03/11/19	2D 3D TSV
US10123984	50	47	HGNC:7154	Neprilysin inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	03/11/19	2D 3D TSV
US10118929	6	3	HGNC:6161 HGNC:6163	Nonanoic and decanoic acid derivatives and uses thereof	SciFluor Life Sciences, Inc.	03/11/19	2D 3D TSV
US10118918	49	48	HGNC:10894	PRMT5 inhibitors and uses thereof	Epizyme Inc	03/11/19	2D 3D TSV
US10118930	465	459	HGNC:9051	Piperidinylpyrazolopyrimidinones and their use	Bayer Pharma Aktiengesellschaft	03/11/19	2D 3D TSV
US10117858	15	13	HGNC:1884	Pyridine and pyrazine derivative for the treatment of CF	Novartis AG	03/11/19	2D 3D TSV
US10125144	60	30	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation LLC	03/11/19	2D 3D TSV
US10118902	223	210	HGNC:8039	Small molecule agonists of neurotensin receptor 1	Sanford Burnham Prebys Medical Discovery Institute	03/11/19	2D 3D TSV
US10117864	67	62	HGNC:9600	Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof	Bayer Pharma Aktiengesellschaft	03/11/19	2D 3D TSV
US10125133	13	13	HGNC:29079	Substituted [1,2,4]triazolo[1,5-a]pyridines and substituted [1,2,4]triazolo[1,5-a]pyrazines as LSD1 inhibitors	Incyte Corporation	03/11/19	2D 3D TSV
US10117944	14	14	HGNC:3430	Targeted therapeutics	Madrigal Pharmaceuticals Inc	03/11/19	2D 3D TSV
US10124003	52	49	HGNC:3689	Therapeutic agent for FGFR inhibitor-resistant cancer	Taiho Pharmaceutical Co., Ltd	03/11/19	2D 3D TSV
US10112941	441	334	HGNC:13575	Tricyclic compounds as anticancer agents	Bristol-Myers Squibb Co.	03/11/19	2D 3D TSV
US10111866	2	2		Compounds as rearranged during transfection (RET) inhibitors	GlaxoSmithKline	03/10/19	2D 3D TSV
US10112934	40	20	HGNC:2160 HGNC:2159	(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles	Centrexion Therapeutics Corporation	03/04/19	2D 3D TSV
US10112931	783	397		3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH	Novartis AG	03/04/19	2D 3D TSV
US10112932	62	20	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Benzoxazepin oxazolidinone compounds and methods of use	Genentech Inc	03/04/19	2D 3D TSV
US10112944	41	37	HGNC:11892	Heterocyclic compounds useful as inhibitors of TNF	Bristol-Myers Squibb Co.	03/04/19	2D 3D TSV
US10112940	116	115	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	03/04/19	2D 3D TSV
US10112935	516	247	HGNC:10251 HGNC:10252	Indazolyl thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease	Lycera Corporation	03/04/19	2D 3D TSV
US10112928	32	32		Inhibitors of SYK	Hoffmann-La Roche Inc	03/04/19	2D 3D TSV
US10112929	379	248	HGNC:10252	Lactams as inhibitors of rock	Bristol-Myers Squibb Co.	03/04/19	2D 3D TSV
US10112937	1877	363	HGNC:8537	P2X7 modulators and methods of use	Janssen Pharmaceutica NV	03/04/19	2D 3D TSV
US10112950	116	116	HGNC:29079	Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors	Incyte Corporation	03/04/19	2D 3D TSV
US10112942	1229	555	HGNC:9967	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	03/04/19	2D 3D TSV
US10112939	112	103	HGNC:10252	Tied-back benzamide derivatives as potent rock inhibitors	Bristol-Myers Squibb Co.	03/04/19	2D 3D TSV
US9586925	22	11	HGNC:108 HGNC:983	1-(dimethylamino)ethyl-substituted 6H-benzo[C]chromen-6-ones against senile dementia	NOBEL ILAÇ	03/02/19	2D 3D TSV
US9586950	104	25	HGNC:4849 HGNC:4848	2-pyridyloxy-3-ester-4-nitrile orexin receptor antagonists	Merck Sharp & Dohme Corp	03/02/19	2D 3D TSV
US10112926	1455	226	HGNC:8979 HGNC:8978 HGNC:8984 HGNC:3942 HGNC:8974 HGNC:8977 HGNC:8976	Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors	Novartis AG	03/02/19	2D 3D TSV
US9586945	38	35	HGNC:7044	Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	03/02/19	2D 3D TSV
US9586942	17	17	HGNC:7044	Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	03/02/19	2D 3D TSV
US10112895	14	14		Antivirals against molluscum contagiosum virus	University of Pennsylvania	03/02/19	2D 3D TSV
US9586949	157	78	HGNC:8978 HGNC:8977	Aza-heteroaryl compounds as PI3K-gamma inhibitors	Incyte Corporation	03/02/19	2D 3D TSV
US9586962	903	449	HGNC:4849 HGNC:4848	Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators	Janssen Pharmaceutica NV	03/02/19	2D 3D TSV
US9585879	28	28	HGNC:4617	Heterocyclic GSK-3 allosteric modulators	Consejo Superior de Investigaciones Cientificas (CSIC)	03/02/19	2D 3D TSV
US9586970	27	27	HGNC:8772	Imidazole derivatives	Hoffmann-La Roche Inc	03/02/19	2D 3D TSV
US10112922	40	19	HGNC:1133 HGNC:6171	Inhibitor of bruton's tyrosine kinase	Centaurus BioPharma Co., Ltd	03/02/19	2D 3D TSV
US9586948	51	51	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	03/02/19	2D 3D TSV
US10112899	326	315		Isoindoline derivatives for use in the treatment of a viral infection	ViiV HEALTHCARE UK LIMITED	03/02/19	2D 3D TSV
US9586965	16	4	HGNC:6190 HGNC:6192 HGNC:1133 HGNC:6193	Pyrrolo[2,3-d]pyrimidine compounds as inhibitors of protein kinases	ACEA BIOSCIENCES INC.	03/02/19	2D 3D TSV
US9586900	121	121	HGNC:4479	Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists	Bristol-Myers Squibb Co.	03/02/19	2D 3D TSV
US10111875	18	6	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolopyrimidine compounds and uses thereof	HUTCHINSON MEDIPHARMA LIMITED	03/02/19	2D 3D TSV
US10112911	75	75		Substituted cyanoguanidines as oral anti-virals	AbbVie Inc	03/02/19	2D 3D TSV
US10112907	52	13		Substituted indazoles for treating tendon and/or ligament injuries	Novartis AG	03/02/19	2D 3D TSV
US9585881	56	19	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases	Ono Pharmaceutical Co., Ltd	03/02/19	2D 3D TSV
US9586959	169	110	HGNC:5297 HGNC:17383 HGNC:5184	Substituted tricyclic heterocycles as histamine 4 receptor inhibitors	C&C RESEARCH LABORATORIES	03/02/19	2D 3D TSV
US10106550	6	6	HGNC:270	Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor	SUZHOU KANGRUN PHARMACEUTICALS INC.	02/24/19	2D 3D TSV
US10106522	12	12	HGNC:5182	Benzimidazole derivatives as antihistamine agents	Faes Farma SA	02/24/19	2D 3D TSV
US10106552	43	43	HGNC:24615	Compounds inhibiting eukaryotic elongation factor 2 kinase activity	Longevica Pharmaceuticals, Inc.	02/24/19	2D 3D TSV
US10106521	18	9	HGNC:108 HGNC:983	Eckol derivatives, methods of synthesis and uses thereof	Phloronol, Inc.	02/24/19	2D 3D TSV
US10106571	23	22		HCV polymerase inhibitors	Medivir AB	02/24/19	2D 3D TSV
US10106535	45	45	HGNC:14063	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	02/24/19	2D 3D TSV
US10106534	274	216	HGNC:29012 HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	02/24/19	2D 3D TSV
US10106527	488	237	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	02/24/19	2D 3D TSV
US10106501	428	416		Nuclear receptor modulators	AbbVie Inc	02/24/19	2D 3D TSV
US10106557	26	6	HGNC:9475 HGNC:3528 HGNC:3535	Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof	NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD.	02/24/19	2D 3D TSV
US10106504	83	68		Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	02/24/19	2D 3D TSV
US10106508	94	47	HGNC:3236	Quinazoline heterocyclic compound as EGFR kinase inhibitor and preparation and application thereof	BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED	02/24/19	2D 3D TSV
US10106553	70	70	HGNC:4498	Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes	Janssen Pharmaceutica NV	02/24/19	2D 3D TSV
US10106510	60	59		Substituted isoxazoles for treating cancer	Epizyme Inc	02/24/19	2D 3D TSV
US10106559	152	43	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Co.	02/24/19	2D 3D TSV
US10100045	36	36	HGNC:1406	3-aryl-2H-pyrazolo[4,3-b]pyridine compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	02/21/19	2D 3D TSV
US10100030	25	13	HGNC:11526 HGNC:2637	Carboxymethyl piperidine derivative	Kissei Pharmaceutical Co., Ltd	02/21/19	2D 3D TSV
US10100051	14	14	HGNC:1232	Compound of 5-hydroxyl-1,7-naphthyridine substituted by aryloxy or heteroaryloxy, preparation method thereof and pharmaceutical use thereof	SHENYANG SUNSHINE PHARMACEUTICAL CO. LTD.	02/21/19	2D 3D TSV
US10100058	717	364	HGNC:1462	Fused heterocyclic compounds as CaM kinase inhibitors	Gilead Sciences Inc	02/21/19	2D 3D TSV
US10100048	7	7	HGNC:4617	Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors	AbbVie Deutschland GmbH & Co. KG	02/21/19	2D 3D TSV
US10100057	199	198	HGNC:4597	Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same	SK Biopharmaceuticals Co. Ltd	02/21/19	2D 3D TSV
US10100046	31	30	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	02/21/19	2D 3D TSV
US10100049	112	27	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	THERAVANCE BIOPHARMA R&D IP, LLC	02/21/19	2D 3D TSV
US10100019	177	72	HGNC:6091 HGNC:427	N2-(2-methoxyphenyl)pyrimidine derivative, method for preparing same, and pharmaceutical composition for cancer prevention or treatment containing same as active ingredient	Korea Research Institute of Chemical Technology	02/21/19	2D 3D TSV
US10105349	6	6		Organic compounds	Intra-Cellular Therapies Inc	02/21/19	2D 3D TSV
US10105367	304	300	HGNC:8775	Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones	Dart NeuroScience (Cayman) Ltd	02/21/19	2D 3D TSV
US9580437	709	243	HGNC:17101	Triazolopyrimidine compounds and uses thereof	Novartis AG	02/21/19	2D 3D TSV
US10100042	12	10	HGNC:4498	[5,6]—fused bicyclic antidiabetic compounds	Merck Sharp & Dohme Corp	02/21/19	2D 3D TSV
US9580418	156	52	HGNC:19310 HGNC:8987	Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors	Incyte Corporation	02/19/19	2D 3D TSV
US9580423	200	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	02/19/19	2D 3D TSV
US9580396	112	56	HGNC:934 HGNC:933	C6-spiro iminothiadiazine dioxides as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	02/19/19	2D 3D TSV
US9580449	298	295	HGNC:1133	Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity	Merck Patent GmbH	02/19/19	2D 3D TSV
US9580415	36	21	HGNC:6251 HGNC:550	Compounds	Proximagen Limited	02/19/19	2D 3D TSV
US9580412	102	21	HGNC:4540 HGNC:1605 HGNC:1607 HGNC:6026 HGNC:6027	Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases	Galderma Research & Development	02/19/19	2D 3D TSV
US9580432	134	84	HGNC:1133 HGNC:3236	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	02/19/19	2D 3D TSV
US9579320	492	473	HGNC:11491	Inhibitors of syk and JAK protein kinases	Portola Pharmaceuticals Inc	02/19/19	2D 3D TSV
US9579407	4	4	HGNC:8772	Radiolabeled compounds and their use as radiotracers for quantitative imaging of phosphodiesterase (PDE10A) in mammals	Takeda Pharmaceutical Co., Ltd	02/19/19	2D 3D TSV
US9580411	11	10	HGNC:497	Substituted sulfonamide compounds	Hoffmann-La Roche Inc	02/19/19	2D 3D TSV
US9580442	52	13	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors	Karus Therapeutics Limited	02/19/19	2D 3D TSV
US10098883	105	101		(Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use	Bayer Pharma Aktiengesellschaft	02/18/19	2D 3D TSV
US10100018	136	83	HGNC:3166	Amide derivatives as lysophosphatidic acid receptor antagonists	Takeda Pharmaceutical Co., Ltd	02/18/19	2D 3D TSV
US10098902	131	66	HGNC:663 HGNC:664	Arginase inhibitors as therapeutics	Mars, Incorporated	02/18/19	2D 3D TSV
US10100016	53	53	HGNC:17989	Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof	Shanghai Yingli Pharmaceutical Co., Ltd	02/18/19	2D 3D TSV
US10099993	358	176	HGNC:4595 HGNC:4594	Metabotropic glutamate receptor positive allosteric modulators (PAMS) and uses thereof	Sanford-Burnham Medical Research Institute	02/18/19	2D 3D TSV
US10098900	5	5	HGNC:1133	Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases	Zhejiang DTRM Biopharma Co. Ltd	02/18/19	2D 3D TSV
US10098888	22	3	HGNC:2625 HGNC:3527 HGNC:2622 HGNC:2623 HGNC:2621	Substituted benzene compounds	Epizyme Inc	02/18/19	2D 3D TSV
US10093671	40	37		2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection	Hoffmann-La Roche Inc	01/23/19	2D 3D TSV
US9573958	74	73	HGNC:6171	Benzimidazole derivatives as ITK inhibitors	Principia Biopharma Inc	01/23/19	2D 3D TSV
US9572792	5	5	HGNC:3165	Coumarin compounds as receptor modulators with therapeutic utility	Allergan Inc	01/23/19	2D 3D TSV
US9572802	96	92	HGNC:1952	Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity	Theravance Respiratory Company LLC	01/23/19	2D 3D TSV
US10093683	74	58	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	01/23/19	2D 3D TSV
US10093697	12	11	HGNC:10906	IBAT inhibitors for the treatment of liver diseases	TBA	01/23/19	2D 3D TSV
US9573957	151	151	HGNC:6710	Inhibitors of leukotriene production	Boehringer Ingelheim International GmbH	01/23/19	2D 3D TSV
US9573930	122	119	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	01/23/19	2D 3D TSV
US9573961	95	88	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	01/23/19	2D 3D TSV
US9573943	86	29	HGNC:19310 HGNC:8987	Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	Genentech Inc	01/23/19	2D 3D TSV
US10092575	221	217	HGNC:8775	Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compounds	Dart NeuroScience (Cayman) Ltd	01/23/19	2D 3D TSV
US10093673	15	13		Tetracyclic pyridone compounds as antivirals	Novartis AG	01/23/19	2D 3D TSV
US9572811	103	89	HGNC:1133	Treatment of dry eye	Principia Biopharma Inc	01/23/19	2D 3D TSV
US10093646	286	292	HGNC:6943 HGNC:936 HGNC:992 HGNC:9644	1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2	Novartis AG	01/22/19	2D 3D TSV
US10093664	74	72	HGNC:6851	Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease	The University of Texas System	01/22/19	2D 3D TSV
US10093631	12	6	HGNC:12805 HGNC:17989	Bifunctional compounds and use for reducing uric acid levels	Acquist LLC	01/22/19	2D 3D TSV
US10093658	29	14	HGNC:12805 HGNC:17989	Bifunctional compounds and use for reducing uric acid levels	Acquist LLC	01/22/19	2D 3D TSV
US10093651	5	5	HGNC:32311	Ghrelin O-acyl transferase inhibitors	Eli Lilly and Company	01/22/19	2D 3D TSV
US10093655	81	77	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	01/22/19	2D 3D TSV
US10093635	56	56	HGNC:17038	MAGL inhibitors	ABIDE THERAPEUTICS, INC.	01/22/19	2D 3D TSV
US10093663	110	89	HGNC:1037	Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof	Novartis AG	01/22/19	2D 3D TSV
US10093660	261	220	HGNC:7110 HGNC:7111	Sulfoximine substituted quinazolines for pharmaceutical compositions	EVOTEC INTERNATONAL GMBH	01/22/19	2D 3D TSV
US10093650	24	23	HGNC:7045	Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors	Bristol-Myers Squibb Co.	01/22/19	2D 3D TSV
US10092570	368	340	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	01/18/19	2D 3D TSV
US10092529	7	7		Necrosis inhibitors	National Institute of Biological Sciences, Beijing	01/18/19	2D 3D TSV
US10092563	408	133	HGNC:8978 HGNC:8980 HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	01/18/19	2D 3D TSV
US10092556	28	14	HGNC:11393 HGNC:11390	Piperidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	01/18/19	2D 3D TSV
US10087191	87	87	HGNC:4485	Piperidine derivative and preparation method and pharmaceutical use thereof	Jiangsu Hengrui Medicine Co., Ltd.	01/18/19	2D 3D TSV
US10092551	173	167	HGNC:895	Spiro-thiazolones	Hoffmann-La Roche Inc	01/18/19	2D 3D TSV
US10087144	18	18		Agents for use in the treatment of cardiovascular and inflammatory diseases structurally based on 4(1 H)-quinolone	UCL Business PLC	01/17/19	2D 3D TSV
US10085988	5	5		Aglaroxin C and derivatives as HCV entry inhibitors	SRI International	01/17/19	2D 3D TSV
US10085983	38	19	HGNC:3236	Azabicyclo derivatives, process for preparation thereof and medical use thereof	Shanghai Haiyan Pharmaceutical Technology Co., Ltd.	01/17/19	2D 3D TSV
US10087188	204	192	HGNC:1133	Benzamide imidazopyrazine Btk inhibitors	Merck Sharp & Dohme Corp	01/17/19	2D 3D TSV
US10087167	32	32		Benzofurans substituted with secondary benzamide as HCV inhibitors	Bristol-Myers Squibb Co.	01/17/19	2D 3D TSV
US10087181	30	30	HGNC:15983	Compound as WNT signaling inhibitor, composition, and use thereof	CUREGENIX, INC.	01/17/19	2D 3D TSV
US10087185	125	122	HGNC:13628	Fused bicylic pyridine compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	01/17/19	2D 3D TSV
US10087187	510	91	HGNC:8978 HGNC:8971 HGNC:8972 HGNC:3942 HGNC:8977	Imidazopyridazine derivatives as PI3KB inhibitors	Janssen Pharmaceutica NV	01/17/19	2D 3D TSV
US10085984	272	135	HGNC:2592 HGNC:2591	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals (Bermuda), Ltd.	01/17/19	2D 3D TSV
US10087143	160	158	HGNC:10582	Pyridone amides as modulators of sodium channels	Vertex Pharmaceuticals Inc	01/17/19	2D 3D TSV
US10085986	20	20	HGNC:2671	Pyrimidinone compounds and their use	Takeda Pharmaceutical Co., Ltd	01/17/19	2D 3D TSV
US9567341	72	22	HGNC:4586 HGNC:6251 HGNC:2625	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	01/17/19	2D 3D TSV
US10087148	49	49	HGNC:11049	Quinazolines as biogenic amine transport modulators	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTE OF HEALTH	01/17/19	2D 3D TSV
US9567334	150	147	HGNC:3688	Quinolone derivatives as fibroblast growth factor receptor inhibitors	Principia Biopharma Inc	01/17/19	2D 3D TSV
US9567324	34	25	HGNC:6307 HGNC:8804	Substituted nicotinamide derivatives as kinase inhibitors	Allergan Inc	01/17/19	2D 3D TSV
US10087178	163	160		Substituted spiropyrido[1,2-a]pyrazine derivative and medicinal use thereof as HIV integrase inhibitor	Japan Tobacco Inc	01/17/19	2D 3D TSV
US10086000	131	124		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp	01/17/19	2D 3D TSV
US10085990	88	64	HGNC:8781 HGNC:8783 HGNC:16841	Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	01/17/19	2D 3D TSV
US9518026	206	103		5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum	University of Washington Through its Center for Commercialization	01/14/19	2D 3D TSV
US9518000	100	98	HGNC:19061	Bicyclo [2.2.1] acid GPR120 modulators	Bristol-Myers Squibb Co.	01/14/19	2D 3D TSV
US9517228	8	8	HGNC:2159	Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes	Jenrin Discovery Inc	01/14/19	2D 3D TSV
US9566312	321	105	HGNC:9253 HGNC:9255 HGNC:9259	Cyclic peptides and use as medicines	Novartis AG	01/14/19	2D 3D TSV
US9567327	3	3		Imidazo[1,2-a]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	01/14/19	2D 3D TSV
US9518055	38	19	HGNC:2592 HGNC:2591	Imidazopyridyl compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme	01/14/19	2D 3D TSV
US9518064	131	113	HGNC:3540 HGNC:3537	Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation	Bristol-Myers Squibb Co.	01/14/19	2D 3D TSV
US9566277	5	5	HGNC:270	Methods of using phthalazinone ketone derivatives	Jiangsu Hansoh Pharmaceutical Co., Ltd.	01/14/19	2D 3D TSV
US9567339	358	354		Primary carboxamides as BTK inhibitors	AbbVie Inc	01/14/19	2D 3D TSV
US9567338	61	60		Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligands	LABORATORIOS DEL DR. ESTEVE S.A.	01/14/19	2D 3D TSV
US9518052	676	168	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolopyridines and pyrazolopyrimidines	Pfizer Inc	01/14/19	2D 3D TSV
US9567320	29	17	HGNC:6112 HGNC:17967	Pyridazinone-amides derivatives	Merck Patent GmbH	01/14/19	2D 3D TSV
US9567304	358	356	HGNC:2730	Quinazolinedione derivative	Chugai Seiyaku Kabushiki Kaisha	01/14/19	2D 3D TSV
US9518060	98	94	HGNC:9612	Substituted pyrrolo[3,4-c]pyrazoles as PKC kinase inhibitors	Pfizer Inc	01/14/19	2D 3D TSV
US9567333	14	7	HGNC:2592 HGNC:2591	Triazolopyridyl compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	01/14/19	2D 3D TSV
US10081635	20	5	HGNC:6190 HGNC:6193 HGNC:12440	Substituted N-(pyrrolidine-3-yl)-7H-pyrrolo[2,3-D]pyrimidine-4-amine as janus kinase inhibitor	YANG JI CHEMICAL CO., LTD.	01/13/19	2D 3D TSV
US10081632	21	19	HGNC:10432	Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-α]pyrazine-2-carboxamides as RSK inhibitors	PHOENIX MOLECULAR DESIGNS	01/13/19	2D 3D TSV
US10081629	107	49	HGNC:9599	Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof	Jiangsu Hengrui Medicine Co., Ltd.	01/12/19	2D 3D TSV
US10081623	35	35	HGNC:3529	Diamide macrocycles that are FXIa inhibitors	Bristol-Myers Squibb Co.	01/12/19	2D 3D TSV
US10081617	134	94	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	01/12/19	2D 3D TSV
US10081606	46	23	HGNC:3236	Heteroaryl compounds and uses thereof	Celgene CAR LLC	01/12/19	2D 3D TSV
US10081602	42	12	HGNC:8154 HGNC:8156	Opioid agonists and uses thereof	Nektar Therapeutics	01/12/19	2D 3D TSV
US10081622	12	4	HGNC:5465 HGNC:11393 HGNC:427	Substituted indazole derivatives active as kinase inhibitors	Nerviano Medical Sciences srl	01/12/19	2D 3D TSV
US10080750	243	243		Aminopyrimidine derivatives for use as modulators of kinase activity	Merck Patent GmbH	01/11/19	2D 3D TSV
US10077277	38	26	HGNC:6190 HGNC:8977	Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors	Incyte Corporation	01/11/19	2D 3D TSV
US10023583	56	28	HGNC:6656	Bicyclic pyridine compound	Astellas Pharma Inc	01/11/19	2D 3D TSV
US10023592	505	494	HGNC:13575	Bromodomain inhibitors	Celgene Quanticel Research Inc	01/11/19	2D 3D TSV
US10077289	76	38	HGNC:9253 HGNC:9316	Cyclosporins modified on the MeBmt sidechain by heterocyclic rings	Allergan Inc	01/11/19	2D 3D TSV
US10081601	41	31	HGNC:4177	Glucocerebrosidase modulators and uses thereof	Alectos Therapeutics Inc	01/11/19	2D 3D TSV
US10077272	23	23	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	01/11/19	2D 3D TSV
US10023576	117	115	HGNC:8977	Heteroaryl substituted pyrrolotriazine amine compounds as PI3K inhibitors	Bristol-Myers Squibb Co.	01/11/19	2D 3D TSV
US10077269	372	104		Imidazopyridazine compounds	Pfizer Inc	01/11/19	2D 3D TSV
US10077273	54	33	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	01/11/19	2D 3D TSV
US10077265	28	13	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives	Bayer Pharma Aktiengesellschaft	01/11/19	2D 3D TSV
US10077266	142	140	HGNC:4515	Substituted pyrido[3,4-b]pyrazines as GPR6 modulators	Takeda Pharmaceutical Co., Ltd	01/11/19	2D 3D TSV
US10080744	176	85		Thiazoles as modulators of RORγt	Janssen Pharmaceutica NV	01/11/19	2D 3D TSV
US10077247	54	54	HGNC:9596	Tricyclic spiro compound	Ono Pharmaceutical Co., Ltd	01/11/19	2D 3D TSV
US10023575	202	66	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	01/10/19	2D 3D TSV
US10023564	139	39	HGNC:4544 HGNC:10251 HGNC:289 HGNC:10013	G protein-coupled receptor kinase 2 inhibitors and methods for use of the same	The Regents of the University of Michigan	01/10/19	2D 3D TSV
US10023562	168	150	HGNC:17967	Heteroaryl substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Co.	01/10/19	2D 3D TSV
US10023570	1162	715		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array BioPharma Inc	01/10/19	2D 3D TSV
US10023539	107	59	HGNC:20982	Aryl-cyanoguanidine compounds	Bayer Pharma Aktiengesellschaft	01/06/19	2D 3D TSV
US10023561	74	74	HGNC:16672	Fumagillol heterocyclic compounds and methods of making and using same	Zafgen, Inc.	01/06/19	2D 3D TSV
US10023543	122	119	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	01/06/19	2D 3D TSV
US10023559	262	131		Substituted azetidine derivatives	Hoffman-La Roche Inc	01/06/19	2D 3D TSV
US10023557	451	312	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	01/06/19	2D 3D TSV
US9884865	4	4	HGNC:10597	Azaspiro[4.5] decane derivatives and use thereof	Purdue Pharma LP	01/05/19	2D 3D TSV
US9884874	18	18	HGNC:13575	Bromodomain-inhibiting compounds and pharmaceutical composition comprising same for preventing or treating a cancer	KAINOS MEDICINE, INC.	01/05/19	2D 3D TSV
US9884843	140	112	HGNC:12680	Cyclic sulfone and sulfoximine analogs and uses thereof	PELOTON THERAPEUTICS, INC.	01/05/19	2D 3D TSV
US9884878	845	837	HGNC:436	FLAP modulators	Janssen Pharmaceutica NV	01/05/19	2D 3D TSV
US9884860	365	353	HGNC:6278	Fused pyrroledicarboxamides and their use as pharmaceuticals	Sanofi	01/05/19	2D 3D TSV
US9884850	16	4	HGNC:4852 HGNC:14064 HGNC:4853	Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors	Acetylon Pharmaceuticals Inc	01/05/19	2D 3D TSV
US9884828	117	117	HGNC:18618	Substituted cinnolines as inhibitors of LRRK2 kinase activity	Imago Pharmaceuticals Inc	01/05/19	2D 3D TSV
US9884868	605	303	HGNC:11773	TGF-beta inhibitors	Rigel Pharmaceuticals, Inc	01/05/19	2D 3D TSV
US10022387	157	76	HGNC:8978 HGNC:8977	Aza-heteroaryl compounds as PI3K-gamma inhibitors	Incyte Corporation	12/31/18	2D 3D TSV
US10023528	16	14	HGNC:4685	Branched 3-phenylpropionic acid derivatives and their use	Bayer Pharma Aktiengesellschaft	12/31/18	2D 3D TSV
US10023534	22	18	HGNC:1133	Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK	Bristol-Myers Squibb Co.	12/31/18	2D 3D TSV
US10023519	68	66	HGNC:23693	Cyclobutane containing carboxylic acid GPR120 modulators	Bristol-Myers Squibb Co.	12/31/18	2D 3D TSV
US10030026	52	17	HGNC:4586 HGNC:6251	Difluoroethylpyridine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	12/31/18	2D 3D TSV
US10030016	798	774		Heterocyclic compounds useful as PDK1 inhibitors	Sunesis Pharmaceuticals Inc	12/31/18	2D 3D TSV
US10022352	15	14	HGNC:1884	Modulators of ATP-binding cassette transporters	Vertex Pharmaceuticals Inc	12/31/18	2D 3D TSV
US10030047	55	55		Peptide macrocycles against acinetobacter baumannii	Hoffmann-La Roche Inc	12/31/18	2D 3D TSV
US10022376	676	168	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolopyridines and pyrazolopyrimidines	Pfizer Inc	12/31/18	2D 3D TSV
US10022354	246	243	HGNC:9886	Pyrrolidine amide compounds as histone demethylase inhibitors	Genentech Inc	12/31/18	2D 3D TSV
US10022461	105	105	HGNC:6893	Pyrrolo[2,3-C]pyridines as imaging agents for neurofibrilary tangles	Merck Sharp & Dohme Corp	12/31/18	2D 3D TSV
US10030027	248	233	HGNC:4685	Soluble guanylate cyclase stimulators	Merck Sharp & Dohme Corp	12/31/18	2D 3D TSV
US10030020	677	265	HGNC:17038	Spirocycle compounds and methods of making and using same	ABIDE THERAPEUTICS, INC.	12/31/18	2D 3D TSV
US10030025	205	47	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Substituted [1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Ogeda SA	12/31/18	2D 3D TSV
US10030004	207	36	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	Compounds and methods of use	Medivation Technologies LLC	12/30/18	2D 3D TSV
US10029993	68	68	HGNC:2592	Disubstituted 1, 2, 4-triazine compound	Mitsubishi Tanabe Pharma Corporation	12/30/18	2D 3D TSV
US10030012	100	85	HGNC:1953 HGNC:1951	Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists	Heptares Therapeutics Limited	12/30/18	2D 3D TSV
US10028961	1070	390		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals Inc	12/30/18	2D 3D TSV
US10034864	21	21	HGNC:6059	1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase	Incyte Holdings Corporation	12/25/18	2D 3D TSV
US10034861	606	190	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	12/25/18	2D 3D TSV
US10035761	33	11	HGNC:11050 HGNC:11048 HGNC:11049	Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives	Revivia Pharmaceuticals, Inc.	12/25/18	2D 3D TSV
US10035797	73	61	HGNC:5253	Fused amino pyridine as HSP90 inhibitors	Curis Inc	12/25/18	2D 3D TSV
US10035814	18	18	HGNC:11726	Guanine analogs as telomerase substrates and telomere length affectors	Geron Corporation	12/25/18	2D 3D TSV
US10035794	139	47	HGNC:934 HGNC:933	Heterocyclic derivatives and their use in the treatment of neurological disorders	Novartis AG	12/25/18	2D 3D TSV
US10035777	109	108	HGNC:19679	Heterocyclic kinase inhibitors	Bristol-Myers Squibb Co.	12/25/18	2D 3D TSV
US10035760	349	273		Inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	12/25/18	2D 3D TSV
US10035778	119	17	HGNC:6160 HGNC:6161 HGNC:6163 HGNC:6153 HGNC:6156	Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists	Saint Louis University	12/25/18	2D 3D TSV
US10028960	106	42	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrimidine compounds as JAK kinase inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	12/25/18	2D 3D TSV
US10035780	9	9		Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof	TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.	12/25/18	2D 3D TSV
US10035792	71	71	HGNC:5253	Resorcinol derivative as HSP90 inhibitor	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	12/25/18	2D 3D TSV
US10035804	122	61	HGNC:2592 HGNC:2591	Spirodiamine derivatives as aldosterone synthase inhibitors	Hoffman-La Roche Inc	12/25/18	2D 3D TSV
US10028934	74	37	HGNC:6342 HGNC:3765	Substituted indazole derivatives active as kinase inhibitiors	Nerviano Medical Sciences srl	12/25/18	2D 3D TSV
US10034939	22	22	HGNC:6059	Synergistic combination of immunologic inhibitors for the treatment of cancer	The University of Chicago	12/25/18	2D 3D TSV
US10040788	63	57		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	12/22/18	2D 3D TSV
US10040789	28	17		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	12/22/18	2D 3D TSV
US10040815	21	20	HGNC:15631	3-substituted 5-amino-6H-thiazolo[4,5-d]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc	12/22/18	2D 3D TSV
US10040790	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Holdings Corporation	12/22/18	2D 3D TSV
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US10040798	117	115	HGNC:17967	Pyrrolopyridazine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	12/22/18	2D 3D TSV
US10040805	19	17	HGNC:1133	Substituted imidazo[1,5-a]pyrazines as Btk inhibitors	Merck Sharp & Dohme Corp	12/22/18	2D 3D TSV
US10040802	109	109	HGNC:17967	Thienopyrazine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	12/22/18	2D 3D TSV
US10071086	115	105	HGNC:16913 HGNC:583	1H-pyrazolo[3,4-b]pyridines and therapeutic uses thereof	Samumed, LLC	12/21/18	2D 3D TSV
US10072005	105	103	HGNC:1950	4-azaindole derivatives	Eisai R&D Management Co., Ltd	12/21/18	2D 3D TSV
US10072026	1144	279	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile	THERAVANCE BIOPHARMA R&D IP, LLC	12/21/18	2D 3D TSV
US10071992	17	13	HGNC:16940	Diacylglycerol acyl transferase 2 inhibitors	Pfizer Inc	12/21/18	2D 3D TSV
US10072025	140	62	HGNC:6190 HGNC:6192	Ethyl N-boc piperidinyl pyrazolo pyridones as Janus kinase inhibitors	Merck Sharp & Dohme Corp	12/21/18	2D 3D TSV
US10071984	129	55	HGNC:13606 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	12/21/18	2D 3D TSV
US10040779	237	79	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	12/21/18	2D 3D TSV
US10071998	58	29	HGNC:934 HGNC:933	Iminothiadiazine dioxides bearing an amine-linked substituent as BACE inhibitors, compositions, and their use	TBA	12/21/18	2D 3D TSV
US10072034	37	27	HGNC:11491 HGNC:11283 HGNC:11892 HGNC:6025 HGNC:5439	Kinase inhibitors	Respivert Limited	12/21/18	2D 3D TSV
US10071974	169	85	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists	Boehringer Ingelheim International GmbH	12/21/18	2D 3D TSV
US10071957	138	98	HGNC:10593 HGNC:10597	N-substituted benzamides and methods of use thereof	Genentech Inc	12/21/18	2D 3D TSV
US10071994	3	3		N-sulfonyl homoserine lactone derivatives, preparation method and use thereof	Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China	12/21/18	2D 3D TSV
US10071110	33	17	HGNC:3688	Phosphonate compounds	The Regents of the University of California	12/21/18	2D 3D TSV
US10071965	42	15		Pyridone FabI inhibitors and uses thereof	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK	12/21/18	2D 3D TSV
US10072008	7	7	HGNC:8157	Spiro-isoquinoline-3,4′-piperidine compounds having activity against pain	ESTEVE PHARMACEUTICALS S.A.	12/21/18	2D 3D TSV
US10071988	647	640	HGNC:10477	Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators	Janssen Pharmaceutica NV	12/21/18	2D 3D TSV
US10072016	247	111	HGNC:12405 HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	Columbia University	12/21/18	2D 3D TSV
US10071995	38	14	HGNC:6371	Substituted oxopyridine derivatives	Bayer Pharma Aktiengesellschaft	12/21/18	2D 3D TSV
US10071991	18	7		Substituted pyridine derivatives useful as c-fms kinase inhibitors	Janssen Pharmaceutica NV	12/21/18	2D 3D TSV
US10072001	527	262	HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	12/21/18	2D 3D TSV
US10040781	1854	611	HGNC:6192 HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	12/21/18	2D 3D TSV
US10072003	130	109	HGNC:4594	Tetrahydronaphthyridine derivatives as mGluR2-negative allosteric modulators, compositions, and their use	TBA	12/21/18	2D 3D TSV
US9878996	42	14	HGNC:7872 HGNC:7873	2-imidazolyl-pyrimidine scaffolds as potent and selective inhibitors of neuronal nitric oxide synthase	Northwestern University	12/12/18	2D 3D TSV
US9884814	277	277	HGNC:2529	Acylguanidines for treating osteoarthritis	Merck Patent GmbH	12/12/18	2D 3D TSV
US10065972	193	189	HGNC:17929	Bicyclic or tricyclic heterocyclic compound	Mitsubishi Tanabe Pharma Corporation	12/12/18	2D 3D TSV
US9884048	326	314	HGNC:6871	ERK inhibitors	Merck Sharp & Dohme Corp	12/12/18	2D 3D TSV
US9556117	95	95	HGNC:8537	Indole carboxamide derivatives as P2X7 receptor antagonists	Actelion Pharmaceuticals Ltd	12/12/18	2D 3D TSV
US9556190	94	45	HGNC:4849 HGNC:4848	Piperidinyloxy lactone orexin receptor antagonists	Merck Sharp & Dohme Corp	12/12/18	2D 3D TSV
US9879013	12	4	HGNC:4037 HGNC:6735 HGNC:6524	Purinone derivative	Ono Pharmaceutical Co., Ltd	12/12/18	2D 3D TSV
US9879032	46	45	HGNC:438	Pyridine compounds	Daiichi Sankyo Company, Limited	12/12/18	2D 3D TSV
US9550796	455	128	HGNC:2348 HGNC:1104	Pyrrolopyrrolone derivatives and their use as BET inhibitors	Novartis AG	12/12/18	2D 3D TSV
US9951047	4	1	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Salt of monocyclic pyridine derivative and crystal thereof	Eisai R&D Management Co., Ltd	12/12/18	2D 3D TSV
US9556188	218	214	HGNC:1133	Substituted imidazo[1,2-b]pyrazoles as bruton'S tyrosine kinase modulators	BeiGene, Ltd	12/12/18	2D 3D TSV
US9556179	949	469	HGNC:2453 HGNC:2452	Substituted imidazoles as casein kinase 1 D/E inhibitors	Bristol-Myers Squibb Co.	12/12/18	2D 3D TSV
US9556187	1933	467	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same	Nissan Chemical Industries, Ltd	12/12/18	2D 3D TSV
US9879026	27	27	HGNC:2528	Substituted spirocycles	Boehringer Ingelheim International GmbH	12/12/18	2D 3D TSV
US9878991	226	137	HGNC:12716	TRPV1 antagonists including dihydroxy substituent and uses thereof	Purdue Pharma LP	12/12/18	2D 3D TSV
US9877957	81	78	HGNC:16940	Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharp & Dohme Corp	12/12/18	2D 3D TSV
US10059669	24	21	HGNC:933	2-amino-3,5-difluoro-3,6-dimethyl-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors for treating alzheimer's disease	H. Lundbeck A/S	12/11/18	2D 3D TSV
US10058540	19	18	HGNC:933	2-amino-5,5-difluoro-6-(fluoromethyl)-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	12/11/18	2D 3D TSV
US10059713	296	296	HGNC:4501	3-substituted 2-amino-indole derivatives	Takeda Pharmaceutical Co., Ltd	12/11/18	2D 3D TSV
US10059705	452	174	HGNC:6190 HGNC:6192	Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors	Merck Sharp & Dohme Corp	12/11/18	2D 3D TSV
US10065941	574	554	HGNC:8534	Aminotriazine derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	12/11/18	2D 3D TSV
US10059667	216	144	HGNC:4498	Antidiabetic compounds	Merck Sharp & Dohme Corp	12/11/18	2D 3D TSV
US10058534	230	137	HGNC:3467	Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders	Novartis AG	12/11/18	2D 3D TSV
US10065961	90	31	HGNC:11526 HGNC:11527 HGNC:11528 HGNC:3446	Chiral N-acyl-5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof	Ogeda SA	12/11/18	2D 3D TSV
US10059709	84	28	HGNC:6190 HGNC:6192 HGNC:12440	Compounds	Elanco Tiergesundheit AG	12/11/18	2D 3D TSV
US10064873	147	74		Compounds and compositions for treating HIV with derivatives of Betulin	GlaxoSmithKline	12/11/18	2D 3D TSV
US10064853	26	13	HGNC:8548	Compounds for use in methods for treating diseases or conditions mediated by protein disulfide isomerase	Beth Israel Deaconess Medical Center, Inc.	12/11/18	2D 3D TSV
US10065967	43	43	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp	12/11/18	2D 3D TSV
US10059695	67	37	HGNC:3236	Cot modulators and methods of use thereof	Gilead Sciences Inc	12/11/18	2D 3D TSV
US10065963	620	239	HGNC:6190 HGNC:8978 HGNC:8977	Heterocyclic compounds as PI3K-γ inhibitors	Incyte Corporation	12/11/18	2D 3D TSV
US10065948	96	88	HGNC:14065	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	12/11/18	2D 3D TSV
US10059687	128	44	HGNC:29012 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	12/11/18	2D 3D TSV
US10058549	3	3		Imidazo[1,2-α]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	12/11/18	2D 3D TSV
US10065953	19	17		Imidazo[1,2-A]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO. 5) LIMITED	12/11/18	2D 3D TSV
US10065945	9	9	HGNC:7045	Isoquinoline derivatives as MGAT2 inhibitors	Merck Sharp & Dohme Corp	12/11/18	2D 3D TSV
US10059668	41	35	HGNC:29079	LSD1 inhibitors	Mirati Therapeutics Inc	12/11/18	2D 3D TSV
US10064861	81	41	HGNC:6112 HGNC:17967	Macrocyclic pyridazinone derivatives	Merck Patent GmbH	12/11/18	2D 3D TSV
US10058550	788	582	HGNC:339	Methods of treating heart failure	Amgen Inc	12/11/18	2D 3D TSV
US10059688	43	9	HGNC:427 HGNC:3236	Protein tyrosine kinase modulators and methods of use	Betta Pharmaceuticals Co., Ltd	12/11/18	2D 3D TSV
US10059720	288	148	HGNC:6656	Pyridine derivative	Astellas Pharma Inc	12/11/18	2D 3D TSV
US10065928	42	42	HGNC:4910	Quinolinone compound and use thereof	Sunshine Lake Pharma Co., Ltd	12/11/18	2D 3D TSV
US10065973	23	20	HGNC:15631	Substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc	12/11/18	2D 3D TSV
US10065950	358	353		Substituted thiazoles as HIV integrase inhibitors	Japan Tobacco Inc	12/11/18	2D 3D TSV
US10065970	215	210	HGNC:8975	Tricyclic PI3K inhibitor compounds and methods of use	Genentech Inc	12/11/18	2D 3D TSV
US10071079	2922	952	HGNC:15633 HGNC:15631 HGNC:15632	[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds	Bristol-Myers Squibb Co.	12/11/18	2D 3D TSV
US9718813	168	97	HGNC:23437 HGNC:3594	Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer	Janssen Pharmaceutica NV	12/10/18	2D 3D TSV
US9718825	648	629	HGNC:10810	N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals	Sanofi	12/10/18	2D 3D TSV
US9549932	488	431	HGNC:882	2-(morpholin-4-yl)-1,7-naphthyridines	Bayer Pharma Aktiengesellschaft	11/29/18	2D 3D TSV
US9718828	489	483	HGNC:1133	BTK Inhibitors	Merck Sharp & Dohme Corp	11/29/18	2D 3D TSV
US9550771	93	91		Keto-imidazopyridine derivatives as RORc modulators	Genentech Inc	11/29/18	2D 3D TSV
US9718822	68	48	HGNC:8031	Macrocyclic compounds as Trk kinase inhibitors	Array BioPharma Inc	11/29/18	2D 3D TSV
US9718854	20	20	HGNC:25155	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	11/29/18	2D 3D TSV
US9718820	90	86		Substituted aza-bicyclic imidazole derivatives useful TRPM8 receptor modulators	Janssen Pharmaceutica NV	11/29/18	2D 3D TSV
US9550775	130	95	HGNC:10597	Substituted triazolopyridines and methods of use thereof	Genentech Inc	11/29/18	2D 3D TSV
US9718814	375	111	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	11/28/18	2D 3D TSV
US9718819	182	181		Non-nucleoside reverse transcriptase inhibitors	Merck Sharp & Dohme Corp	11/28/18	2D 3D TSV
US9718812	213	123	HGNC:8537	Substituted thiazole or oxazole P2X7 receptor antagonists	Axxam S.P.A.	11/28/18	2D 3D TSV
US9718809	87	82	HGNC:8875	Bisarylsulfonamides useful in the treatment of inflammation and cancer	Kancera AB	11/27/18	2D 3D TSV
US9718800	115	111	HGNC:8976	Chromenone derivatives	AstraZeneca AB	11/27/18	2D 3D TSV
US9718808	144	140	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	11/27/18	2D 3D TSV
US9718793	138	136	HGNC:5253	Isoxazole compounds as inhibitors of heat shock proteins	The Institute of Cancer Research	11/27/18	2D 3D TSV
US9718792	101	99		Isoxazoline hydroxamic acid derivatives as LpxC inhibitors	Novartis AG	11/27/18	2D 3D TSV
US9718790	2250	2236	HGNC:8534	Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same	Shionogi & Co., Ltd	11/27/18	2D 3D TSV
US9718803	375	373	HGNC:8772	Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors	Amgen Inc	11/27/18	2D 3D TSV
US9718771	48	48	HGNC:3165	Aniline derivative, pharmaceutical composition containing same, and use thereof	Kissei Pharmaceutical Co., Ltd	11/16/18	2D 3D TSV
US9718787	9	9	HGNC:270	Poly (ADP-ribose) polymerase inhibitor	CHENGDU DIAO PHARMACEUTICAL GROUP CO., LTD.	11/16/18	2D 3D TSV
US9718780	6	6	HGNC:10597	Substituted pyridines as sodium channel blockers	TBA	11/16/18	2D 3D TSV
US9714242	13	7	HGNC:5297	Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists	Bayer Intellectual Property GmbH	11/15/18	2D 3D TSV
US9714234	70	33	HGNC:6192 HGNC:1133	Carbazole carboxamide compounds	Bristol-Myers Squibb Co.	11/15/18	2D 3D TSV
US9713651	56	55		Compositions, methods, and systems for the synthesis and use of imaging agents	Lantheus Medical Imaging, Inc.	11/15/18	2D 3D TSV
US9714236	207	69		Compounds and methods for inhibiting JAK	AstraZeneca AB	11/15/18	2D 3D TSV
US9713612	30	30	HGNC:15983	Compounds for treatment of cancer	CUREGENIX, INC.	11/15/18	2D 3D TSV
US9714252	7	7	HGNC:10597	Cyclic sulfonamides as sodium channel blockers	Purdue Pharma LP	11/15/18	2D 3D TSV
US9714241	375	110	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	11/15/18	2D 3D TSV
US9714266	46	46	HGNC:386	Estra-1,3,5(10),16-tetraene-3-carboxamides for inhibition of 17.beta.-hydroxysteroid dehydrogenase (AKR1C3)	Bayer Pharma Aktiengesellschaft	11/15/18	2D 3D TSV
US9714224	8	7	HGNC:338	Heterocyclic compounds and methods of their use	Novartis AG	11/15/18	2D 3D TSV
US9714230	511	153	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	Celgene Quantical Research, Inc.	11/15/18	2D 3D TSV
US9713606	584	356	HGNC:2528 HGNC:2536	Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	11/15/18	2D 3D TSV
US9714247	452	147	HGNC:6735 HGNC:1133 HGNC:11283	Multiple kinase pathway inhibitors	Tolero Pharmaceuticals Inc	11/15/18	2D 3D TSV
US9717745	5	5	HGNC:1133	Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases	Zhejiang DTRM Biopharma Co. Ltd	11/15/18	2D 3D TSV
US9718760	257	133	HGNC:8583 HGNC:775	Plasminogen activator inhibitor-1 inhibitors and methods of use thereof	University of Michigan	11/15/18	2D 3D TSV
US9714249	134	33	HGNC:13575 HGNC:1103 HGNC:2348 HGNC:1104	Pyrazolo-pyrrolidin-4-one derivatives and their use in the treatment of disease	Novartis AG	11/15/18	2D 3D TSV
US9714235	40	20	HGNC:3430 HGNC:3236	Quinazoline derivatives, compositions thereof, and use as pharmaceuticals	Shanghai Fochon Pharmaceutical Co., Ltd.	11/15/18	2D 3D TSV
US9717714	14	14	HGNC:1869	Spirocyclic CETP inhibitors	Merck Sharp & Dohme Corp	11/15/18	2D 3D TSV
US9714221	654	217	HGNC:3467	Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof	Sanofi	11/15/18	2D 3D TSV
US9714232	72	38	HGNC:5286	Substituted piperazine compounds and methods of use thereof	Sunshine Lake Pharma Co., Ltd	11/15/18	2D 3D TSV
US9714244	46	33	HGNC:6251 HGNC:12761	Substituted pyrido[4,3-d]pyrimidines as Wee-1 inhibitors	ALMAC DISCOVERY LIMITED	11/15/18	2D 3D TSV
US9556130	73	73	HGNC:19995	4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139	Takeda Pharmaceutical Co., Ltd	11/08/18	2D 3D TSV
US9550741	612	77	HGNC:3023 HGNC:12679 HGNC:5286	Benzoisothiazole compounds and methods of treating schizophrenia	Shanghai Institute of Pharmaceutical Industry	11/08/18	2D 3D TSV
US9556150	59	59	HGNC:1133	Inhibitors of bruton's tyrosine kinase	F. Hoffmann-La Roche Inc	11/08/18	2D 3D TSV
US9708370	88	51		Azapeptides as CD36 binding compounds	VALORISATION-RECHERCHE, LIMITED PARTNERSHIP	11/07/18	2D 3D TSV
US9546162	91	24	HGNC:9594 HGNC:9596	Compounds and methods for skin repair	Allergan Inc	11/07/18	2D 3D TSV
US9533987	230	114	HGNC:6371 HGNC:6357	Heterocyclic derivates	Kalvista Pharmaceuticals Limited	11/07/18	2D 3D TSV
US9546164	648	527	HGNC:10593 HGNC:10597	Substituted benzamides and methods of use thereof	Genentech Inc	11/07/18	2D 3D TSV
US9708337	36	36	HGNC:19679	Aryl amide-based kinase inhibitors	Bristol-Myers Squibb Co.	11/05/18	2D 3D TSV
US9708336	2511	825		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp	11/05/18	2D 3D TSV
US9708359	143	131		Pyrrolopyrimidine nucleosides and analogs thereof	Chimerix, Inc.	11/05/18	2D 3D TSV
US9708340	96	48	HGNC:3560 HGNC:3559	Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors	Hoffmann-La Roche Inc	11/05/18	2D 3D TSV
US9708333	86	34	HGNC:6190 HGNC:7027 HGNC:12446 HGNC:8977	Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors	Incyte Corporation	11/01/18	2D 3D TSV
US9708309	24	8	HGNC:6833 HGNC:6834 HGNC:29079	Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use	Oryzon Genomics, S.A.	10/31/18	2D 3D TSV
US9708311	143	143	HGNC:9596	Benzimidazole derivatives as EP4 antagonists	Bayer Pharma Aktiengesellschaft	10/31/18	2D 3D TSV
US9708318	856	187	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	10/31/18	2D 3D TSV
US9708302	46	23	HGNC:1950	Flouro-naphthyl derivatives	Hoffmann-La Roche Inc	10/31/18	2D 3D TSV
US9708313	142	139	HGNC:4515	Substituted pyrido[3,4-b]pyrazines as GPR6 modulators	Takeda Pharmaceutical Co., Ltd	10/31/18	2D 3D TSV
US9708325	62	45	HGNC:15631	Sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc	10/31/18	2D 3D TSV
US9708279	100	50	HGNC:427	2-acylaminothiazoles for the treatment of cancer	UNIVERSITÁ	10/30/18	2D 3D TSV
US10053471	17	17	HGNC:9385	Azabenzimidazole derivatives	Boehringer Ingelheim International GmbH	10/30/18	2D 3D TSV
US9708266	40	21	HGNC:11526 HGNC:2637	Cyclohexyl pyridine derivative	Kissei Pharmaceutical Co., Ltd	10/30/18	2D 3D TSV
US9708253	135	123		Cyclohexyl sulfone RORγ modulators	Bristol-Myers Squibb Co.	10/30/18	2D 3D TSV
US9701672	77	73	HGNC:7045	Dihydropyridinone MGAT2 inhibitors for use in the treatment of metabolic disorders	Bristol-Myers Squibb Co.	10/30/18	2D 3D TSV
US9708275	12	11	HGNC:338	Heterocyclic compounds and methods for their use	Novartis AG	10/30/18	2D 3D TSV
US9707233	368	352	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	10/30/18	2D 3D TSV
US9708272	22	22	HGNC:19288	Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase	TES Pharma S.r.l.	10/30/18	2D 3D TSV
US9700563	3	3	HGNC:8154	Kappa opioid receptor compounds	MediSynergies, LLC	10/30/18	2D 3D TSV
US10053462	195	56	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	10/30/18	2D 3D TSV
US9701669	34	19	HGNC:3332 HGNC:6251	Preparation and use of 7a-amide substituted- 6,6-difluoro bicyclic himbacine derivatives as PAR-1 receptor antagonists	Merck Sharp & Dohme Corp	10/30/18	2D 3D TSV
US9708269	7	7	HGNC:1232	Process for making isoquinoline compounds	FibroGen Inc	10/30/18	2D 3D TSV
US9701670	374	91	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Pyrazolyl-ureas as kinase inhibitors	Respivert Limited	10/30/18	2D 3D TSV
US10053465	286	93	HGNC:6190 HGNC:7027 HGNC:12446 HGNC:8977	Pyrrolopyrimidine derivatives as TAM inhibitors	Incyte Corporation	10/30/18	2D 3D TSV
US9708268	42	12	HGNC:14901 HGNC:5981 HGNC:16404	ROR modulators and their uses	INNOV17 LLC	10/30/18	2D 3D TSV
US9707205	16	15	HGNC:3167 HGNC:3165	S1P receptors modulators and their use thereof	Akaal Pharma PTY Ltd	10/30/18	2D 3D TSV
US9701693	4	4	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	10/30/18	2D 3D TSV
US9701685	18	13	HGNC:6973	Spiropyrrolidines as MDM2 inhibitors	Hudson Biopharma Inc.	10/30/18	2D 3D TSV
US9708295	51	41	HGNC:427	Substituted 2-aminopyridine protein kinase inhibitor	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	10/30/18	2D 3D TSV
US10053463	422	125	HGNC:8537	Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators	Janssen Pharmaceutica NV	10/30/18	2D 3D TSV
US9708270	91	89	HGNC:19061	Substituted spiropiperidinyl compounds useful as GPR120 agonists	Merck Sharp & Dohme Corp	10/30/18	2D 3D TSV
US9701663	37	11	HGNC:14900 HGNC:5981 HGNC:16404	Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof	INNOV17 LLC	10/30/18	2D 3D TSV
US9708274	328	298	HGNC:7110 HGNC:7111	Sulfoximine substituted quinazolines for pharmaceutical compositions	EVOTEC INTERNATIONAL GMBH	10/30/18	2D 3D TSV
US10053461	41	40		Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection	Hoffmann-La Roche Inc	10/30/18	2D 3D TSV
US9701638	16	16		Therapeutic hydroxyquinolones	Rutgers, The State University of New Jersey	10/30/18	2D 3D TSV
US9701691	25	25	HGNC:11491	Thienopyrimidine compounds	Hoffman-La Roche Inc	10/30/18	2D 3D TSV
US9550763	437	434	HGNC:8534	Heterocyclic ring and carbocyclic derivative	Shionogi & Co., Ltd	10/19/18	2D 3D TSV
US9546173	190	151	HGNC:6871 HGNC:10430 HGNC:10432	Substituted pyrrolo[3,4-d]pyrimidines as kinase inhibitors	Novartis AG	10/19/18	2D 3D TSV
US10053433	20	10	HGNC:644	Androgen receptor antagonists	The Regents of the University of California	10/18/18	2D 3D TSV
US10053454	88	88	HGNC:13575	Carbazole compounds useful as bromodomain inhibitors	Bristol-Myers Squibb Co.	10/18/18	2D 3D TSV
US10053456	375	111	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	10/18/18	2D 3D TSV
US10053455	22	22	HGNC:11491	Diazaspiroalkaneone-substituted oxazole derivatives as spleen tyrosine kinase inhibitors	AB SCIENCE	10/18/18	2D 3D TSV
US10053434	24	22		Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	10/18/18	2D 3D TSV
US10053458	216	107	HGNC:427	Pyrimidine-2,4-diamine derivative and anticancer pharmaceutical composition comprising same as effective ingredient	Korea Research Institute of Chemical Technology	10/18/18	2D 3D TSV
US10053431	514	247		Tetrahydro-benzodiazepinones	Hoffmann-La Roche Inc	10/18/18	2D 3D TSV
US9556139	260	245	HGNC:4502	6-substituted phenoxychroman carboxylic acid derivatives	Array BioPharma Inc	10/17/18	2D 3D TSV
US9556135	339	168	HGNC:2529 HGNC:933	Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use	Amgen Inc	10/17/18	2D 3D TSV
US10047118	7	7		C17-aryl substituted betulinic acid analogs	ViiV HEALTHCARE UK (NO. 5) LIMITED	10/17/18	2D 3D TSV
US10047086	158	158	HGNC:29079	Imidazopyridines and imidazopyrazines as LSD1 inhibitors	Incyte Corporation	10/17/18	2D 3D TSV
US9556143	18	5	HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals Inc	10/17/18	2D 3D TSV
US9556168	60	60		N-alkylated indole and indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	10/17/18	2D 3D TSV
US9556148	86	29	HGNC:6190 HGNC:6192 HGNC:6193	N-cyanomethylamides as inhibitors of janus kinase	Cadila Healthcare Limited	10/17/18	2D 3D TSV
US10052306	333	328	HGNC:4586	Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B	CADENT THERAPEUTICS, INC.	10/17/18	2D 3D TSV
US9555024	35	26	HGNC:6833 HGNC:6834 HGNC:29079	Substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors	University of Utah Research Foundation	10/17/18	2D 3D TSV
US9555022	102	101	HGNC:12401	Substituted triazolopyridines	Bayer Intellectual Property GmbH	10/17/18	2D 3D TSV
US10047080	42	21	HGNC:4540	(R)-2-methyl-piperazine derivatives as CXCR3 receptor modulators	IDORSIA PHARMACEUTICALS Ltd	10/10/18	2D 3D TSV
US10045974	14	12	HGNC:933	2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	10/10/18	2D 3D TSV
US9556175	46	46	HGNC:3009	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and thier use as pharmaceutical compositions	Boehringer Ingelheim International GmbH	10/10/18	2D 3D TSV
US10047073	12	11	HGNC:14063	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	10/10/18	2D 3D TSV
US10047084	43	37	HGNC:8979 HGNC:3942	Imidazolone derivatives, pharmaceutical compositions and uses thereof	BEIJING FORELANDPHARMA CO. LTD.	10/10/18	2D 3D TSV
US10047093	120	102	HGNC:6251	Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors	Tolero Pharmaceuticals Inc	10/10/18	2D 3D TSV
US9556191	8	30	HGNC:3430 HGNC:8975 HGNC:3236	Aminoquinazoline derivatives and their salts and methods of use thereof	Sunshine Lake Pharma Co., Ltd	10/05/18	2D 3D TSV
US9556160	76	37	HGNC:550	Guanidine compound	Astellas Pharma Inc	10/03/18	2D 3D TSV
US9562012	23	23		PPAR-sparing compounds for the treatment of metabolic diseases	Metabolic Solutions Development Company, LLC	10/03/18	2D 3D TSV
US9561238	6	3	HGNC:3467 HGNC:3468	Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy	Donesta Bioscience B.V.	10/03/18	2D 3D TSV
US10047098	188	90	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminopyrimidinone compounds as bace inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	10/02/18	2D 3D TSV
US10047103	384	313	HGNC:3540 HGNC:3535	Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation	Bristol-Myers Squibb Co.	10/02/18	2D 3D TSV
US10047097	105	105	HGNC:8031	Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds	Array BioPharma Inc	10/02/18	2D 3D TSV
US10047092	276	91	HGNC:8537	Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators	Janssen Pharmaceutica NV	10/02/18	2D 3D TSV
US10047096	454	216	HGNC:6307 HGNC:8804	Substituted pyridobenzodiazepinone-derivatives and use thereof	Bayer Pharma Aktiengesellschaft	10/02/18	2D 3D TSV
US9556181	21	11		Substituted pyrazolopyrimidinylamino-indazoles	Bayer Pharma Aktiengesellschaft	09/30/18	2D 3D TSV
US9540377	1285	1155		2,6,7,8 substituted purines as HDM2 inhibitors	Merck Sharp & Dohme Corp	09/26/18	2D 3D TSV
US9556157	6	4	HGNC:3527	Enhancer of zeste homolog 2 inhibitors	GlaxoSmithKline	09/26/18	2D 3D TSV
US9556170	3	3	HGNC:29079	Substituted-1H-benzo[d]imidazole series compounds as lysine-specific demethylase 1 (LSD1) inhibitors	University of Utah Research Foundation	09/26/18	2D 3D TSV
US9546152	448	115	HGNC:4849 HGNC:4848	2-pyridyloxy-3-substituted-4-nitrile orexin receptor antagonists	Merck Sharp & Dohme Corp	09/18/18	2D 3D TSV
US9546153	514	427	HGNC:17967	Bicyclic heterocycle substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Co.	09/18/18	2D 3D TSV
US9533992	75	71	HGNC:8795	PDE9 inhibitors with imidazo triazinone backbone	TBA	09/18/18	2D 3D TSV
US9550778	52	52		Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5	Vanderbilt University	09/18/18	2D 3D TSV
US9556111	23	23		Tertiary amines for use in the treatment of cardiac disorders	UNIVERSITETET I OSLO	09/18/18	2D 3D TSV
US9556145	22	10	HGNC:4849 HGNC:4848	2-pyridyloxy-4-ester orexin receptor antagonists	Merck Sharp & Dohme Corp	09/07/18	2D 3D TSV
US9540359	15	15	HGNC:933	Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity	Shionogi & Co., Ltd	09/07/18	2D 3D TSV
US9556147	7	7	HGNC:1133	Inhibitors of bruton's tyrosine kinase	HOFFMANN-LA INC.	09/07/18	2D 3D TSV
US9550781	26	26		Kinase modulating compounds, compositions containing the same and use thereof	Centaurus BioPharma Co., Ltd	09/07/18	2D 3D TSV
US9556132	41	39	HGNC:6293	Tetrazole derivatives and their use as potassium channel modulators	Saniona A/S	09/07/18	2D 3D TSV
US9540396	38	38	HGNC:6840	6-arylamino pyridone carboxamide as MEK inhibitors	Centaurus BioPharma Co., Ltd	08/28/18	2D 3D TSV
US9550755	5	5	HGNC:2771	Complement pathway modulators and uses thereof	Novartis AG	08/28/18	2D 3D TSV
US9546168	29	28	HGNC:6871	ERK inhibitors	Merck Sharp & Dohme Corp	08/28/18	2D 3D TSV
US9550774	2	2	HGNC:3357	Dihydropyrido pyrimidine compounds as autotaxin inhibitors	Eli Lilly and Company	08/25/18	2D 3D TSV
US9527857	211	76	HGNC:1771 HGNC:1773	HSPC-sparing treatments for RB-positive abnormal cellular proliferation	GI Therapeutics, Inc.	08/25/18	2D 3D TSV
US9540379	222	110	HGNC:8772	(1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases	Boehringer Ingelheim International GmbH	08/24/18	2D 3D TSV
US9539260	567	272	HGNC:8975 HGNC:8977	Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives	Novartis AG	08/24/18	2D 3D TSV
US9540357	74	19	HGNC:9594 HGNC:9596	15-aryl prostaglandins as EP4 agonists, and methods of use thereof	Allergan Inc	08/16/18	2D 3D TSV
US9540323	274	267	HGNC:8539	7-hydroxy-indolinyl antagonists of P2Y1 receptor	Bristol-Myers Squibb Co.	08/16/18	2D 3D TSV
US9540388	197	56	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	08/16/18	2D 3D TSV
US9527851	130	79	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrole six-membered heteroaryl ring derivative, preparation method thereof, and medicinal uses thereof	Jiangsu Hengrui Medicine Co., Ltd.	08/16/18	2D 3D TSV
US9540352	14	14	HGNC:3020	Substituted 1,7-naphthyridines as dopamine D1 ligands	Pfizer Inc	08/16/18	2D 3D TSV
US9670229	31	29	HGNC:5297	5-HT3 receptor antagonists	Takeda Pharmaceutical Co., Ltd	08/07/18	2D 3D TSV
US9522914	174	174	HGNC:896	Azole derivative	Taisho Pharmaceutical Co., Ltd	08/07/18	2D 3D TSV
US9540364	19	19	HGNC:9376	Benzimidazole tetrahydrofuran derivatives	Merck Sharp & Dohme Corp	08/07/18	2D 3D TSV
US9676777	3	3		Compounds useful for producing an optically active diazabicyclooctane compound	Meiji Seika Pharma Co., Ltd	08/07/18	2D 3D TSV
US9533999	64	64	HGNC:6293	Fused thiazin-3-ones as KCA3.1 inhibitors	Boehringer Ingelheim International GmbH	08/07/18	2D 3D TSV
US9670231	368	84	HGNC:9829 HGNC:3236	Fused tricyclic amide compounds as multiple kinase inhibitors	BeiGene, Ltd	08/07/18	2D 3D TSV
US9670230	12	12	HGNC:8772	Heteroaryl compounds and methods of use thereof	Sunovion Pharmaceuticals Inc	08/07/18	2D 3D TSV
US9676783	105	105		Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds	Array BioPharma Inc	08/07/18	2D 3D TSV
US9670255	3	2		Modified biotin, mutant streptavidin, and use thereof	SAVID THERAPEUTICS INC.	08/07/18	2D 3D TSV
US9676786	4	4	HGNC:4326	Pharmacologically active compounds	The University of Liverpool	08/07/18	2D 3D TSV
US9676792	4	2	HGNC:6880	Pyrimido-diazepinone compounds and methods of treating disorders	Dana-Farber Cancer Institute Inc	08/07/18	2D 3D TSV
US9540384	58	58	HGNC:8772	Pyrrolidino heterocycles	Hoffmann-La Roche Inc	08/07/18	2D 3D TSV
US9533995	14	14		Substituted N-heteroaryl spirolactam bipyrrolidines, preparation and therapeutic use thereof	Sanofi	08/07/18	2D 3D TSV
US9676782	342	166		Substituted pyrazolo[1,5-a]pyrazines as negative allosteric modulators of metabotropic glutamate receptor 3	Vanderbilt University	08/07/18	2D 3D TSV
US9540373	27	27	HGNC:2528	Substituted spirocycles	Boehringer Ingelheim International GmbH	08/07/18	2D 3D TSV
US9676818	32	32	HGNC:11848	Toll-like receptor 2-agonistic lipopeptides, and method of making the same	University of Kansas	08/07/18	2D 3D TSV
US9670211	45	45		Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection	Hoffmann-La Roche Inc	07/07/18	2D 3D TSV
US9670216	58	33	HGNC:2160 HGNC:2159	Cannabinoid-2 agonists	Allergan Inc	07/07/18	2D 3D TSV
US9670204	211	208	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	Galapagos NV	07/07/18	2D 3D TSV
US9670210	116	116	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	07/07/18	2D 3D TSV
US9670220	66	21	HGNC:3167 HGNC:3165 HGNC:14299	Fused heterocyclic derivatives as S1P modulators	AbbVie B.V.	07/07/18	2D 3D TSV
US9670203	142	101		Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitors	BeiGene, Ltd	07/07/18	2D 3D TSV
US9670212	191	188	HGNC:8977	Inhibitors of PI3K-delta and methods of their use and manufacture	Exelixis Inc	07/07/18	2D 3D TSV
US9670209	69	24	HGNC:1950 HGNC:1952 HGNC:1951	Muscarinic agonists	ACADIA Pharmaceuticals Inc	07/07/18	2D 3D TSV
US9670213	175	34	HGNC:1057 HGNC:3236 HGNC:3765	Pteridine ketone derivative and applications thereof as EGFR, BLK, and FLT3 inhibitor	East China University of Science and Technology	07/07/18	2D 3D TSV
US9670208	48	48		Serine/threonine kinase inhibitors	Array BioPharma Inc	07/07/18	2D 3D TSV
US9670214	404	200		Small molecule myristate inhibitors of Bcr-abl and methods of use	Dana-Farber Cancer Institute Inc	07/07/18	2D 3D TSV
US9670136	210	57	HGNC:6833 HGNC:6834 HGNC:29079	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	05/19/18	2D 3D TSV
US9670142	171	170	HGNC:3594	1,3-diaminocyclopentane carboxamide derivatives	Merck Patent GmbH	05/19/18	2D 3D TSV
US9669034	227	84	HGNC:1780 HGNC:1771	4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group	Bayer Intellectual Property GmbH	05/19/18	2D 3D TSV
US9670161	20	5	HGNC:1780 HGNC:1771	5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group	Bayer Pharma Aktiengesellschaft	05/19/18	2D 3D TSV
US9670157	271	121	HGNC:3530 HGNC:6371 HGNC:9475 HGNC:3535 HGNC:6357 HGNC:9071	Benzylamine derivatives	Kalvista Pharmaceuticals Limited	05/19/18	2D 3D TSV
US9669035	66	32		Combinations comprising PDE 2 inhibitors such as 1-aryl-4-methyl-[1,2,4]triazolo-[4,3-A]]quinoxaline compounds and PDE 10 inhibitors for use in the treatment of neurological of metabolic disorders	Janssen Pharmaceutica NV	05/19/18	2D 3D TSV
US9669095	13	13		Cyclosporin analogues for preventing or treating hepatitis C infection	Enanta Pharmaceuticals Inc	05/19/18	2D 3D TSV
US9670195	3	3	HGNC:7056	Glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	05/19/18	2D 3D TSV
US9669029	114	110		Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	05/19/18	2D 3D TSV
US9669031	313	182	HGNC:7110 HGNC:7111	MNK inhibitors and methods related thereto	eFFECTOR Therapeutics Inc	05/19/18	2D 3D TSV
US9670201	104	104		Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof	Pfizer Inc	05/19/18	2D 3D TSV
US9670191	116	115	HGNC:17364	Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors	Nerviano Medical Sciences srl	05/19/18	2D 3D TSV
US9669028	175	65	HGNC:18618 HGNC:3091	Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors	ARRIEN PHARMACEUTICALS LLC	05/19/18	2D 3D TSV
US9670181	87	83	HGNC:8772 HGNC:8783	Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)	Allergan Inc	05/19/18	2D 3D TSV
US9670194	71	39	HGNC:8979 HGNC:8978 HGNC:8977	Substituted aminopyrimidine compounds and methods of use	CALITOR SCIENCES, LLC	05/19/18	2D 3D TSV
US9670166	297	273	HGNC:3309 HGNC:2622 HGNC:2623 HGNC:2621	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	05/19/18	2D 3D TSV
US9670202	22	21	HGNC:12401	Substituted triazolopyridines	Bayer Pharma Aktiengesellschaft	05/19/18	2D 3D TSV
US9670196	13	12	HGNC:11491	Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors	Merck Sharp & Dohme Corp	05/19/18	2D 3D TSV
US9670193	138	46	HGNC:4852 HGNC:14064	Trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease	Novartis AG	05/19/18	2D 3D TSV
US9676728	19	17	HGNC:1037	2-benzyl-benzimidazole complement factor B inhibitors and uses thereof	Novartis AG	04/16/18	2D 3D TSV
US9675697	203	33		BET bromodomain inhibitors and therapeutic methods using the same	The Regents of the University of Michigan	04/16/18	2D 3D TSV
US9676721	112	111	HGNC:30092	Compounds and compositions for the inhibition of NAMPT	FORMA TM, LLC	04/16/18	2D 3D TSV
US9676701	287	95	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropylamine derivatives useful as LSD1 inhibitors	Oryzon Genomics, S.A.	04/16/18	2D 3D TSV
US9676732	74	74	HGNC:4596	Ethynyl derivatives	Hoffmann-La Roche Inc	04/16/18	2D 3D TSV
US9676712	15	6	HGNC:9594 HGNC:9596	Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions	Cayman Chemical Company Inc	04/16/18	2D 3D TSV
US9676720	29	29	HGNC:9594	Substituted biaryl compound	Ube Industries, Ltd	04/16/18	2D 3D TSV
US9675616	13	7	HGNC:8979	Arylaminoalcohol-substituted 2,3-dihydroimidazo[1,2-C]quinolines	Bayer Intellectual Property GmbH	04/12/18	2D 3D TSV
US9688710	328	160	HGNC:11037 HGNC:11036	Inhibitors of sodium glucose cotransporter 1	Lexicon Pharmaceuticals, Inc.	04/12/18	2D 3D TSV
US9675614	334	329		PRMT5 inhibitors and uses thereof	Epizyme Inc	04/12/18	2D 3D TSV
US9688696	116	115	HGNC:2843	Piperidine/piperazine derivatives	Janssen Pharmaceutica NV	04/12/18	2D 3D TSV
US9688816	46	21	HGNC:3467 HGNC:3468	Polyetherimide compositions and methods for the manufacture and use thereof	SABIC GLOBAL TECHNOLOGIES B.V.	04/12/18	2D 3D TSV
US9675612	45	45		Substituted thiazolopyrimidines	Bayer Pharma Aktiengesellschaft	04/12/18	2D 3D TSV
US9688680	950	313	HGNC:6342	Compositions useful for treating disorders related to kit	BLUEPRINT MEDICINES CORPORATION	03/27/18	2D 3D TSV
US9688695	384	312	HGNC:3540	Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation	Bristol-Myers Squibb Co.	03/27/18	2D 3D TSV
US9688678	37	36	HGNC:896	Oxindole compounds carrying a nitrogen-bound spiro substituent and use thereof for treating vasopressin-related diseases	AbbVie Deutschland GmbH & Co. KG	03/27/18	2D 3D TSV
US9688683	31	30	HGNC:8781	Substituted condensed pyrimidine compounds	GRÜNENTHAL GMBH	03/27/18	2D 3D TSV
US9688684	278	162		Substituted tetrazolo[1,5-a]pyrazines as ROR-gamma inhibitors	Merck Patent GmbH	03/27/18	2D 3D TSV
US9688676	65	64	HGNC:1133	Tyrosine kinase inhibitors	Principia Biopharma Inc	03/27/18	2D 3D TSV
US9688672	450	375		3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH	Novartis AG	03/19/18	2D 3D TSV
US9688668	150	72	HGNC:18859 HGNC:11240	Long chain base sphingosine kinase inhibitors	University of Virginia Patent Foundation	03/19/18	2D 3D TSV
US9688664	8	2	HGNC:3553 HGNC:2625	Modulators of fatty acid amide hydrolase	Janssen Pharmaceutica NV	03/19/18	2D 3D TSV
US9688669	125	113		Oxazolidinones as modulators of mGluR5	Bristol-Myers Squibb Co.	03/19/18	2D 3D TSV
US9688661	139	50	HGNC:6192	Substituted pyrroles active as kinases inhibitors	Nerviano Medical Sciences srl	03/19/18	2D 3D TSV
US9675593	518	518	HGNC:3176	Anti-fibrotic pyridinones	INTERMUNE, Inc.	03/16/18	2D 3D TSV
US9675594	46	23		Arylpyrrolopyridine derived compounds as LRRK2 inhibitors	H. Lundbeck A/S	03/16/18	2D 3D TSV
US9675539	2	2	HGNC:9600	Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives	Duke University	03/16/18	2D 3D TSV
US9675571	28	28	HGNC:6059	Inhibitors of indoleamine 2,3-dioxygenase (IDO)	Bristol-Myers Squibb Co.	03/16/18	2D 3D TSV
US9688645	25	25	HGNC:2300	Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa	Sanofi	03/16/18	2D 3D TSV
US9675591	9	1	HGNC:6290 HGNC:10588 HGNC:10590 HGNC:6231 HGNC:10591 HGNC:10593 HGNC:10585	Methods for treating seizure disorders and pain	The Regents of the University of California	03/16/18	2D 3D TSV
US9675605	83	83	HGNC:6834	Substituted naphthyridine and quinoline compounds as MAO inhibitors	Dart NeuroScience (Cayman) Ltd	03/16/18	2D 3D TSV
US9688642	96	47	HGNC:4498	Substituted pyrazines as GPR40 agonists	Janssen Pharmaceutica NV	03/12/18	2D 3D TSV
US9688643	325	325	HGNC:8534	Triazine derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	03/12/18	2D 3D TSV
US9688638	35	8	HGNC:8154 HGNC:8156	Opioid agonists and uses thereof	Nektar Therapeutics	03/11/18	2D 3D TSV
US9682995	359	122	HGNC:1771 HGNC:12401	Amino-substituted isothiazoles	Bayer Pharma Aktiengesellschaft	03/10/18	2D 3D TSV
US9682993	22	11	HGNC:6973	Anticancer compounds	St. Jude Children's Research Hospital	03/10/18	2D 3D TSV
US9682983	326	66	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	BMP inhibitors and methods of use thereof	The Brigham and Women's Hospital, Inc.	03/10/18	2D 3D TSV
US9688615	706	99	HGNC:1395 HGNC:1394 HGNC:1390 HGNC:10593 HGNC:1389	Benzimidazole inhibitors of the sodium channel	DEGIACOMO, INTERIM TRUSTEE, MARK G.	03/10/18	2D 3D TSV
US9688624	12	6	HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621	DP2 antagonist and uses thereof	Brickell Biotech, Inc.	03/10/18	2D 3D TSV
US9687494	21	11	HGNC:934 HGNC:933	Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	Ambit Biosciences	03/10/18	2D 3D TSV
US9688629	262	223	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Co.	03/10/18	2D 3D TSV
US9687479	520	391	HGNC:6371 HGNC:3535 HGNC:6357	Multisubstituted aromatic compounds as serine protease inhibitors	VERSEON CORPORATION	03/10/18	2D 3D TSV
US9687478	34	34	HGNC:1952	Quinuclidine derivatives and medicinal compositions containing the same	Almirall, S.A.	03/10/18	2D 3D TSV
US9687483	5	2		Treatment of cerebral cavernous malformations and cerebral aneurysms with Rho kinase inhibitors	BIOAXONE BIOSCIENCES, INC.	03/10/18	2D 3D TSV
US9682991	198	91	HGNC:19310 HGNC:8987	Tricyclic compounds for use as kinase inhibitors	FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III	03/10/18	2D 3D TSV
US9682971	220	216	HGNC:436	1,2,5-Substituted benzimidazoles as flap modulators	Janssen Pharmaceutica NV	02/14/18	2D 3D TSV
US9682980	85	83	HGNC:4594	Positive allosteric modulators of mGluR2	Bristol-Myers Squibb Co.	02/14/18	2D 3D TSV
US9682976	324	296	HGNC:6001	Protein kinase C inhibitors and uses thereof	Rigel Pharmaceuticals, Inc	02/14/18	2D 3D TSV
US9682959	6	6	HGNC:4597	Ethynyl derivatives	Hoffmann-La Roche Inc	02/13/18	2D 3D TSV
US9682965	75	75	HGNC:16672	Fumagillol heterocyclic compounds and methods of making and using same	Zafgen, Inc.	02/13/18	2D 3D TSV
US9682966	563	547	HGNC:8154	Kappa opioid ligands	The Scripps Research Institute	02/13/18	2D 3D TSV
US9682967	50	49	HGNC:11186	N-substituted-5-substituted phthalamic acids as sortilin inhibitors	H. Lundbeck A/S	02/13/18	2D 3D TSV
US9682960	137	127		Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety	ENDORECHERCHE, INC.	02/13/18	2D 3D TSV
US9682969	31	26		Phthalazinone compounds and methods for the treatment of cystic fibrosis	Flatley Discovery Lab LLC	02/13/18	2D 3D TSV
US9682968	110	98	HGNC:1037	Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof	Novartis AG	02/13/18	2D 3D TSV
US9682963	28	16	HGNC:10252	Pyridine derivatives as soft rock inhibitors	Redx Pharma PLC	02/13/18	2D 3D TSV
US9682961	26	26	HGNC:15983	Quinazoline derivative	Carna Biosciences, Inc	02/13/18	2D 3D TSV
US9682953	166	95	HGNC:3553	Amide compounds, compositions and applications thereof	Advinus Therapeutics Ltd	02/07/18	2D 3D TSV
US9687476	60	30	HGNC:897 HGNC:895	Bisaryl-bonded aryltriazolones and use thereof	Bayer Intellectual Property GmbH	02/07/18	2D 3D TSV
US9682141	2516	586	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:3942 HGNC:8977	Combination of kinase inhibitors and uses thereof	Intellikine LLC	02/07/18	2D 3D TSV
US9682957	192	95	HGNC:286 HGNC:1952	Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity	Theravance Respiratory Company LLC	02/07/18	2D 3D TSV
US9682940	502	236	HGNC:2160 HGNC:2159	Indazole derivatives useful as CB-1 inverse agonists	Janssen Pharmaceutica NV	02/07/18	2D 3D TSV
US9682955	280	140	HGNC:2160 HGNC:2159	Quinazoline derivatives useful as CB-1 inverse agonists	Janssen Pharmaceutica NV	02/07/18	2D 3D TSV
US9682910	35	35		Series of skin-whitening (lightening) compounds	Unigen, Inc.	02/07/18	2D 3D TSV
US9695195	162	151	HGNC:5297	5-HT3 receptor antagonists	Takeda Pharmaceutical Co., Ltd	02/06/18	2D 3D TSV
US9695205	53	53	HGNC:2771	Amide compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	02/06/18	2D 3D TSV
US9695197	11	6	HGNC:7056	Glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	02/06/18	2D 3D TSV
US9695200	175	92	HGNC:6171 HGNC:9065	Heterocyclic ITK inhibitors for treating inflammation and cancer	Confluence Life Sciences Inc	02/06/18	2D 3D TSV
US9695151	90	41	HGNC:2592 HGNC:2591	3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds	Hoffmann-La Roche Inc	01/26/18	2D 3D TSV
US9695152	84	38	HGNC:2592 HGNC:2591	3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds	Hoffmann-La Roche Inc	01/26/18	2D 3D TSV
US9695194	126	18	HGNC:9475 HGNC:6362 HGNC:3535 HGNC:2523 HGNC:6368 HGNC:2532	Benzoxazinone derivatives for treatment of skin diseases	SIXERA Pharma AB	01/26/18	2D 3D TSV
US9695172	15	5	HGNC:11393 HGNC:18618 HGNC:11390 HGNC:11391 HGNC:13575 HGNC:1105	Diazepane derivatives and uses thereof	Dana-Farber Cancer Institute Inc	01/26/18	2D 3D TSV
US9695175	51	51		Highly selective c-Met inhibitors as anticancer agents	CB THERAPEUTICS INC.	01/26/18	2D 3D TSV
US9695181	15	6	HGNC:4852 HGNC:6307 HGNC:8804	Hydroximic acid derivatives and medical applications therof	DOUBLE RIDER MEDICINE CO., LTD.	01/26/18	2D 3D TSV
US9695174	21	8	HGNC:74 HGNC:40 HGNC:2638 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2621	Inhibitor of breast cancer resistance protein (BCRP)	Millennium Pharmaceuticals Inc	01/26/18	2D 3D TSV
US9695165	82	55	HGNC:3255 HGNC:3691	Inhibitors of the fibroblast growth factor receptor	BLUEPRINT MEDICINES CORPORATION	01/26/18	2D 3D TSV
US9695179	17	17	HGNC:30193	Methods and compositions for inhibition of bromodomain-containing proteins	ConverGene LLC	01/26/18	2D 3D TSV
US9695170	217	199	HGNC:1232	Naphthyridine derivatives as inhibitors of Hypoxia inducible factor (HIF) hydroxylase	FibroGen Inc	01/26/18	2D 3D TSV
US9695160	36	36	HGNC:11305	Piperazine derivatives for treating disorders	The University of Nottingham	01/26/18	2D 3D TSV
US9695183	702	266	HGNC:4849 HGNC:4848	Substituted 7-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	01/26/18	2D 3D TSV
US9695180	119	119		Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors	Incyte Corporation	01/26/18	2D 3D TSV
US9695168	158	158		Substituted imidazo[1,5-α]pyridines and imidazo[1,5-α]pyrazines as LSD1 inhibitors	Incyte Corporation	01/26/18	2D 3D TSV
US9695176	4	4	HGNC:16709	Substituted imidazo[1,5-a]pyrazines as CGRP receptor antagonists	Bristol-Myers Squibb Co.	01/26/18	2D 3D TSV
US9695167	13	13		Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors	Incyte Corporation	01/26/18	2D 3D TSV
US9695185	5	5	HGNC:10597	Synthetic methods for spiro-oxindole compounds	Xenon Pharmaceuticals Inc	01/26/18	2D 3D TSV
US9695163	76	38	HGNC:4849 HGNC:4848	Thiazole orexin receptor antagonists	Merck Sharp & Dohme Corp	01/26/18	2D 3D TSV
US9695149	235	217	HGNC:436	1,2,6-substituted benzimidazoles as flap modulators	Janssen Pharmaceutica NV	01/19/18	2D 3D TSV
US9695118	394	382	HGNC:2730	Benzamide derivative	Chugai Seiyaku Kabushiki Kaisha	01/19/18	2D 3D TSV
US9694016	2555	1061		Biaryl amide compounds as kinase inhibitors	Novartis AG	01/19/18	2D 3D TSV
US9695128	13	13	HGNC:4596	Ethynyl derivatives	Hoffmann-La Roche Inc	01/19/18	2D 3D TSV
US9695132	194	190	HGNC:3691	Heteroaryl compounds and uses thereof	Celgene CAR LLC	01/19/18	2D 3D TSV
US9694018	12	12	HGNC:7967	IBAT inhibitors for the treatment of liver disease	Albireo AB	01/19/18	2D 3D TSV
US9694015	59	10	HGNC:5992 HGNC:10627 HGNC:21163 HGNC:11892 HGNC:6018 HGNC:2434 HGNC:10630	Methods for the treatment of locally advanced breast cancer	Celgene Corporation	01/19/18	2D 3D TSV
US9694024	17	7		Methods of treating retroviral infections and related dosage regimes	Chimerix, Inc.	01/19/18	2D 3D TSV
US9694012	76	38	HGNC:2160 HGNC:2159	Pyrazol derivatives	Hoffmann-La Roche Inc	01/19/18	2D 3D TSV
US9694011	6	2	HGNC:1133	Substituted pyrazolopyrimidines as kinases inhibitors	Jiangsu Medolution Ltd	01/19/18	2D 3D TSV
US9695131	56	50		Substituted uracils as chymase inhibitors	Bayer Pharma Aktiengesellschaft	01/19/18	2D 3D TSV
US9693997	356	293		Antiviral compounds	Hoffmann-La Roche Inc	01/14/18	2D 3D TSV
US9693992	251	249	HGNC:3449	IRE-1α inhibitors	MannKind Corporation	01/14/18	2D 3D TSV
US9694002	648	574	HGNC:10583 HGNC:10593 HGNC:10597	Substituted benzamides and methods of use thereof	Genentech Inc	01/14/18	2D 3D TSV
US9527838	54	54	HGNC:4195	2-pyridinecarboxamide derivatives, compositions containing such compounds, and methods of treatment	Merck Sharp & Dohme Corp	12/04/17	2D 3D TSV
US9527839	25	25	HGNC:9385	Benzimidazole tetrahydropyran derivatives	Merck Sharp & Dohme Corp	12/04/17	2D 3D TSV
US9533969	6	6	HGNC:10289	Materials and method for inhibiting replication protein A and uses thereof	Indiana University Research and Technology Corporation	12/04/17	2D 3D TSV
US9532990	119	119	HGNC:1133	Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors	Zhejiang DTRM Biopharma Co. Ltd	12/04/17	2D 3D TSV
US9504692	48	45	HGNC:6819	Selective inhibition of MALT1 protease by phenothiazine derivatives	HELMHOLTZ ZENTRUM MUNCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH)	12/04/17	2D 3D TSV
US9533989	123	116	HGNC:11491	Substituted pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors	Ziarco Pharma Ltd.	12/04/17	2D 3D TSV
US9533985	193	104	HGNC:6162 HGNC:12663	Sulfonamide derivative and medicinal use thereof	EA Pharma Co., Ltd.	12/04/17	2D 3D TSV
US9522881	71	48	HGNC:6080 HGNC:9671 HGNC:1718 HGNC:9651 HGNC:3069 HGNC:3065 HGNC:21480 HGNC:28110 HGNC:9642 HGNC:9675 HGNC:9652 HGNC:9655 HGNC:9657 HGNC:9659 HGNC:25016 HGNC:9658 HGNC:122 HGNC:9669 HGNC:9647	Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)	Indiana University Research and Technology Corporation	11/27/17	2D 3D TSV
US9512115	58	29	HGNC:9753	Inhibitors	Probiodrug AG	11/27/17	2D 3D TSV
US9505766	158	77	HGNC:1133 HGNC:9077 HGNC:11283	Kinase inhibitors	The Regents of the University of California	11/27/17	2D 3D TSV
US9522910	16	8	HGNC:76	Protein kinase inhibitors (variants), use thereof in treating oncological diseases and a pharmaceutical composition based thereon	OBSHCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYOU “FUSION PHARMA”	11/27/17	2D 3D TSV
US9505762	338	169	HGNC:2160 HGNC:2159	Purine derivatives as CB2 receptor agonists	Hoffmann-La Roche Inc	11/27/17	2D 3D TSV
US9512141	84	42	HGNC:2160 HGNC:2159	Pyrazine derivatives as CB2 receptor agonists	Hoffmann-La Roche Inc	11/27/17	2D 3D TSV
US9512132	76	37	HGNC:2160 HGNC:2159	Pyrazole compounds as CB2 agonists	Hoffmann-La Roche Inc	11/27/17	2D 3D TSV
US9522886	195	90	HGNC:2160 HGNC:2159	Pyridine derivatives	Hoffmann-La Roche Inc	11/27/17	2D 3D TSV
US9505749	527	145	HGNC:270 HGNC:272	Quinazolinone compounds and derivatives thereof	Amgen Inc	11/27/17	2D 3D TSV
US9505780	114	28	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Thienopyranones as kinase and epigenetic inhibitors	Signal Rx Pharmaceuticals Inc	11/27/17	2D 3D TSV
US9512121	47	47	HGNC:7029	[1,2,4] triazol [4,3-A] pyridine derivative, preparation method therefor or medical application thereof	Jiangsu Hansoh Pharmaceutical Co., Ltd.	11/27/17	2D 3D TSV
US9499492	130	42	HGNC:1373 HGNC:1780 HGNC:4638 HGNC:1368	4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amines containing a sulfoximine group	Bayer Pharma Aktiengesellschaft	11/20/17	2D 3D TSV
US9499502	733	363	HGNC:934 HGNC:933	5-substituted iminothiazines and their mono- and dioxides as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	11/20/17	2D 3D TSV
US9512084	40	40	HGNC:1133	Amino pyrimidine derivatives	Novartis AG	11/20/17	2D 3D TSV
US9499547	110	64	HGNC:4638	Amino-substituted imidazopyridazines	Bayer Intellectual Property GmbH	11/20/17	2D 3D TSV
US9493490	60	10	HGNC:391 HGNC:9380 HGNC:9393 HGNC:289 HGNC:4638 HGNC:10430	Boron-containing small molecules	Anacor Pharmaceuticals Inc	11/20/17	2D 3D TSV
US9493486	113	112	HGNC:3357	Diazaspirocycloalkane and azaspirocycloalkane	Hoffmann-La Roches Inc.	11/20/17	2D 3D TSV
US9505745	110	76		Enhancer of zeste homolog 2 inhibitors	GlaxoSmithKline	11/20/17	2D 3D TSV
US9526727	30	29	HGNC:6251	Inhibitors of beta-secretase	Vitae Pharmaceutical, Inc.	11/20/17	2D 3D TSV
US9499482	247	247		Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists	Bristol-Myers Squibb Co.	11/20/17	2D 3D TSV
US9512114	52	22	HGNC:8979 HGNC:8978	Substituted aminopyrimidine compounds and methods of use	CALITOR SCIENCES, LLC	11/20/17	2D 3D TSV
US9512126	25	25	HGNC:12401	Substituted imidazopyridazines	Bayer Intellectual Property GmbH	11/20/17	2D 3D TSV
US9512169	23	19	HGNC:4638	3-substituted estra-1,3,5(10),16-tetraene derivatives, methods for the production thereof, pharmaceutical preparations containing same, and use thereof for the production of medicaments	Bayer Pharma Aktiengesellschaft	11/13/17	2D 3D TSV
US9512068	14	14		Augmenting moieties for anti-inflammatory compounds	Rutgers, The State University of New Jersey	11/13/17	2D 3D TSV
US9493448	168	150	HGNC:10597	Cycloalkane derivatives	Daiichi Sankyo Company, Limited	11/13/17	2D 3D TSV
US9511061	6	1	HGNC:5302 HGNC:5297 HGNC:5295 HGNC:5294	Incontinence treatment methods	IXALTIS	11/13/17	2D 3D TSV
US9505753	69	68	HGNC:2671	Inhibitors of D-amino acid oxidase	The Johns Hopkins University	11/13/17	2D 3D TSV
US9512082	7	7	HGNC:9753	Inhibitors of glutaminyl cyclase	Probiodrug AG	11/13/17	2D 3D TSV
US9493446	1134	565	HGNC:4849 HGNC:4848	Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives	Actelion Pharmaceuticals Ltd	11/13/17	2D 3D TSV
US9512065	5	1	HGNC:9475 HGNC:3528 HGNC:3535 HGNC:9071	Polymorphs of N-[(R)-1-[(S)-1-(4-aminomethyl-benzylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(4-ethoxy-phenyl)-ethyl]-benzamide hydrochloride	Kalvista Pharmaceuticals Limited	11/13/17	2D 3D TSV
US9493485	178	65	HGNC:2529 HGNC:933	Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof	Imago Pharmaceuticals Inc	11/13/17	2D 3D TSV
US9505786	59	59	HGNC:8784	Substituted annulated triazines and use thereof	Bayer Pharma Aktiengesellschaft	11/13/17	2D 3D TSV
US9522888	952	242	HGNC:3167 HGNC:3165	Substituted bicyclic compounds	Bristol-Myers Squibb Co.	11/13/17	2D 3D TSV
US9512130	4	4	HGNC:2637	Substituted imidazopyridazines	Bayer Pharma Aktiengesellschaft	11/13/17	2D 3D TSV
US9493441	222	108	HGNC:6190 HGNC:6192	Acyclic cyanoethylpyrazoles as janus kinase inhibitors	Merck Sharp & Dohme Corp	11/06/17	2D 3D TSV
US9489013	194	97	HGNC:934 HGNC:933	C6-azaspiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	11/06/17	2D 3D TSV
US9493440	239	223		Compounds inhibiting leucine-rich repeat kinase enzyme activity	Merck Sharp & Dohme Corp	11/06/17	2D 3D TSV
US9493432	214	104	HGNC:4849 HGNC:4848	Cyclopentylbenzamide derivatives and their use for the treatment of psychotic and cognitive disorders	Takeda Pharmaceutical Co., Ltd	11/06/17	2D 3D TSV
US9487511	375	113	HGNC:6833 HGNC:6834 HGNC:4638	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	11/06/17	2D 3D TSV
US9522883	1	1	HGNC:7056	Glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	11/06/17	2D 3D TSV
US9505736	16	16		Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation Inc	11/06/17	2D 3D TSV
US9493435	182	174	HGNC:4638	IRE-1α inhibitors	MannKing Corporation	11/06/17	2D 3D TSV
US9492453	77	76	HGNC:391	Protein kinase B inhibitors	AstraZeneca AB	11/06/17	2D 3D TSV
US9505773	18	18	HGNC:3711	Rapamycin analogues and their pharmaceutical use	Isomerase Therapeutics Ltd.	11/06/17	2D 3D TSV
US9504684	11	11	HGNC:11491	Syk inhibitors	Gilead Sciences Inc	11/06/17	2D 3D TSV
US9487512	159	44	HGNC:6833 HGNC:6834 HGNC:4638	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	10/30/17	2D 3D TSV
US9487490	63	63		3-cyclohexenyl and cyclohexyl substituted indole and indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	10/30/17	2D 3D TSV
US9481672	253	246		Bicyclically substituted uracils and the use thereof	Bayer Pharma Aktiengesellschaft	10/30/17	2D 3D TSV
US9487483	128	128	HGNC:2771	Complement pathway modulators and uses thereof	Novartis AG	10/30/17	2D 3D TSV
US9505754	4	1		Compound useful for the treatment of degenerative and inflammatory diseases	Galapagos NV	10/30/17	2D 3D TSV
US9487462	114	29	HGNC:7176 HGNC:7155 HGNC:7166 HGNC:7159	Inhibitors of matrix metalloproteinases	PharmaHungary 2000 Kft.	10/30/17	2D 3D TSV
US9481648	347	120	HGNC:11491 HGNC:11283 HGNC:6251 HGNC:2637 HGNC:4616 HGNC:2623 HGNC:6876	Kinase inhibitors	Respivert Limited	10/30/17	2D 3D TSV
US9505743	3	2	HGNC:7159	Matrix metalloproteinase inhibitors and methods for the treatment of pain and other diseases	TBA	10/30/17	2D 3D TSV
US9487501	114	57		Pyrazole carboxamide compounds and uses thereof	Hoffmann-La Roche Inc	10/30/17	2D 3D TSV
US9475815	228	130	HGNC:4638	Substituted benzothienyl-pyrrolotriazines and uses thereof	BAYER INTELLETUAL PROPERTY GMBH	10/30/17	2D 3D TSV
US9487488	60	60	HGNC:17961	Sulfonamide compound	Mitsubishi Tanabe Pharma Corporation	10/30/17	2D 3D TSV
US9481688	24	1	HGNC:5295 HGNC:5294 HGNC:5182 HGNC:5302 HGNC:281 HGNC:5301 HGNC:3023 HGNC:282 HGNC:3024 HGNC:5289 HGNC:5300 HGNC:283 HGNC:5287 HGNC:4075 HGNC:3020 HGNC:277 HGNC:278	(Thieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl compounds as dual activity H1 inverse agonists/5-HT2A antagonists	Eli Lilly and Company	10/23/17	2D 3D TSV
US9499493	51	50	HGNC:11491	2,4-pyrimidinediamine compounds and their uses	Rigel Pharmaceuticals, Inc	10/23/17	2D 3D TSV
US9499570	14	14	HGNC:8781	Boron containing small molecules	Anacor Pharmaceuticals Inc	10/23/17	2D 3D TSV
US9499561	46	23	HGNC:8975 HGNC:8977	Fused pyrimidine compound, and preparation method, intermediate, composition, and uses thereof	Shanghai Yingli Pharmaceutical Co., Ltd	10/23/17	2D 3D TSV
US9499486	7	1	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6524 HGNC:6876	Kinase inhibitor	Respivert Limited	10/23/17	2D 3D TSV
US9499523	63	21	HGNC:8978 HGNC:8977 HGNC:8976	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	10/23/17	2D 3D TSV
US9475817	402	200	HGNC:2453 HGNC:2452	Pyrazole substituted imidazopyrazines as casein kinase 1 d/e inhibitors	Bristol-Myers Squibb Co.	10/23/17	2D 3D TSV
US9475819	702	282	HGNC:4849 HGNC:4848	Substituted 7-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	10/23/17	2D 3D TSV
US9481682	221	220	HGNC:1133	Substituted benzamides and substituted pyridinecarboxamides as Btk inhibitors	Merck Sharp & Dohme Corp	10/23/17	2D 3D TSV
US9499534	42	42	HGNC:11491	Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors	Merck Sharp & Dohme Corp	10/23/17	2D 3D TSV
US9475813	268	67	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Tricyclic pyrrolopyridine compound, and JAK inhibitor	Nissan Chemical Industries, Ltd	10/23/17	2D 3D TSV
US9469597	210	59	HGNC:6833 HGNC:6834 HGNC:4638	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	10/16/17	2D 3D TSV
US9505765	36	36	HGNC:18157	4-alkoxy/aralkoxy-5-substituted-pyrrolopyrimidine compounds as TAK1 inhibitors in disease treatment	Confluence Life Sciences Inc	10/16/17	2D 3D TSV
US9499542	46	23	HGNC:18618	Arylpyrrolopyridine derived compounds as LRRK2 inhibitors	H. Lundbeck A/S	10/16/17	2D 3D TSV
US9475775	160	78	HGNC:15631 HGNC:15632	Benzazepine dicarboxamide compounds	Hoffmann-La Roche Inc	10/16/17	2D 3D TSV
US9493483	6	5		Benzo [C] isoxazoloazepine bromodomain inhibitors and uses thereof	Constellation Pharmaceuticals, Inc.	10/16/17	2D 3D TSV
US9487554	62	31	HGNC:2593 HGNC:4638	Estra-1,3,5(10),16-tetraene-3-carboxamide derivatives, processes for their preparation, pharmaceutical preparations comprising them and their use for preparing medicaments	Bayer Intellectual Property GmbH	10/16/17	2D 3D TSV
US9469631	130	130	HGNC:19060	N-cyclopropyl-N-piperidinyl-amides, pharmaceutical compositions containing them, and uses thereof	Boehringer Ingelheim International GmbH	10/16/17	2D 3D TSV
US9464084	843	293	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	10/16/17	2D 3D TSV
US9505734	2	1	HGNC:11037 HGNC:11036	Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof	Tianjin Institute of Pharmaceutical Research	10/16/17	2D 3D TSV
US9468661	123	116	HGNC:2771	Pyrrolidine derivatives and their use as complement pathway modulators	Novartis AG	10/16/17	2D 3D TSV
US9493412	34	34	HGNC:6623	Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors	Bristol-Myers Squibb Co.	10/16/17	2D 3D TSV
US9493472	34	31	HGNC:3535	Substituted benzoxazoles	Bayer Pharma Aktiengesellschaft	10/16/17	2D 3D TSV
US9481677	37	37	HGNC:10597	Biaryl ether sulfonamides and their use as therapeutic agents	Xenon Pharmaceuticals Inc	10/10/17	2D 3D TSV
US9493457	3	3	HGNC:550	4,5,6,7-tetrahyroimidazo[4,5-c]pyridine compounds	Proximagen Limited	10/09/17	2D 3D TSV
US9481673	141	22	HGNC:2637 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2621	6-alkynyl-pyridine derivatives	Boehringer Ingelheim International GmbH	10/09/17	2D 3D TSV
US9493431	44	44	HGNC:4638	Apoptosis-inducing agent for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	10/09/17	2D 3D TSV
US9493430	41	41	HGNC:1869	Biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds as CETP inhibitors	Chong Kun Dang Pharmaceutical Corp.	10/09/17	2D 3D TSV
US9493474	60	34	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	10/09/17	2D 3D TSV
US9458201	162	125	HGNC:6932 HGNC:6929	Melanocortin receptor-specific heptapeptides	Palatin Technologies Inc	10/09/17	2D 3D TSV
US9458171	572	568		Pyrrolidinyl sulfone RORγ modulators	Bristol-Myers Squibb Co.	10/09/17	2D 3D TSV
US9505739	11	11	HGNC:933	Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease	Merck Sharp & Dohme Corp	10/09/17	2D 3D TSV
US9464092	229	76	HGNC:1771 HGNC:1773	Transient protection of normal cells during chemotherapy	G1 Therapeutics, Inc.	10/09/17	2D 3D TSV
US9459250	254	250	HGNC:15661	Use of T1R3 venus flytrap region polypeptide to screen for taste modulators	Senomyx Inc	10/09/17	2D 3D TSV
US9464076	131	94		Benzothiophene derivative	Daiichi Sankyo Company, Limited	10/02/17	2D 3D TSV
US9487494	9	9	HGNC:2625	Cyclic hydrocarbon compounds for the treatment of diseases	Leo Pharma A/S	10/02/17	2D 3D TSV
US9481685	8	8		Imaging neuroinflammation	GE Healthcare Limited	10/02/17	2D 3D TSV
US9493447	14	3	HGNC:8791 HGNC:8793 HGNC:8784 HGNC:8773 HGNC:8772 HGNC:8778	Optically active PDE10 inhibitor	Omeros Corporation	10/02/17	2D 3D TSV
US9480684	35	11	HGNC:8154 HGNC:8155	Orvinol and thevinol derivatives useful in the treatment of anxiety or a compulsive disorder	The University of Bath	10/02/17	2D 3D TSV
US9458110	632	285	HGNC:10251 HGNC:10252	Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors	Bristol-Myers Squibb Co.	10/02/17	2D 3D TSV
US9458172	180	168	HGNC:30092	Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives	TBA	10/02/17	2D 3D TSV
US9493429	9	9	HGNC:10597	Substituted benzoxazoles and methods of use thereof	Genentech Inc	10/02/17	2D 3D TSV
US9458113	187	184	HGNC:3309	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	10/02/17	2D 3D TSV
US9458176	245	244	HGNC:4594	Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative	Eisai R&D Management Co., Ltd	10/02/17	2D 3D TSV
US9469608	44	43	HGNC:3535	Thrombin inhibitors	Merck Sharp & Dohme Corp	10/02/17	2D 3D TSV
US9452986	683	619	HGNC:10582 HGNC:10597	6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use	AbbVie Inc	09/25/17	2D 3D TSV
US9453031	272	87	HGNC:8979 HGNC:6251 HGNC:2637 HGNC:9413 HGNC:2625 HGNC:2623 HGNC:2621	Chemical entities	Fundación Centro Nacional de Investigaciones Oncológicas Carlos III	09/25/17	2D 3D TSV
US9475814	83	31	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof	Euroscreen SA	09/25/17	2D 3D TSV
US9475806	21	21	HGNC:1037	Complement factor B inhibitors and uses there of	Novartis AG	09/25/17	2D 3D TSV
US9452990	131	130	HGNC:2771	Complement pathway modulators and uses thereof	Novartis AG	09/25/17	2D 3D TSV
US9464060	136	83	HGNC:13307 HGNC:3166	Compounds	Takeda Pharmaceutical Co., Ltd	09/25/17	2D 3D TSV
US9468642	46	46	HGNC:12401	Imidazopyrazines	Bayer Intellectual Property GmbH	09/25/17	2D 3D TSV
US9447148	197	54	HGNC:6932 HGNC:6929	Melanocortin-1 receptor-specific cyclic peptides	Palatin Technologies Inc	09/25/17	2D 3D TSV
US9469653	23	23	HGNC:6834	Pharmaceutical compositions for preventing or treating degenerative brain disease and method of screening the same	Korea Institute of Science and Technology	09/25/17	2D 3D TSV
US9452998	274	116	HGNC:9393 HGNC:4617 HGNC:9410 HGNC:8987	Protein kinase C inhibitors and methods of their use	Novartis AG	09/25/17	2D 3D TSV
US9481668	1	1		Quinoline inhibitor of the macrophage stimulating 1 receptor MSTR1	Merck Patent GmbH	09/25/17	2D 3D TSV
US9475779	63	55	HGNC:6251 HGNC:3309	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	09/25/17	2D 3D TSV
US9475809	16	16	HGNC:3529	Substituted oxopyridine derivatives and use thereof as factor xia/plasma	Bayer Pharma Aktiengesellschaft	09/25/17	2D 3D TSV
US9469613	4	1	HGNC:171 HGNC:1076	(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide	Gilead Sciences Inc	09/18/17	2D 3D TSV
US9464044	101	98	HGNC:5208	Compound having ability to inhibit 11Beta-HSD1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient	Ahn-Gook Pharmaceutical Co. Ltd	09/18/17	2D 3D TSV
US9447087	91	88	HGNC:4118	Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders	University of Utah Research Foundation	09/18/17	2D 3D TSV
US9469644	7	7	HGNC:1133	Inhibitors of Bruton's tyrosine kinase	Hoffmann-La Roche Inc	09/18/17	2D 3D TSV
US9469639	14	7	HGNC:6307 HGNC:8804	Naphthylurea derivatives and medical applications thereof	Radiant Pharma & Tech. Co., Ltd.	09/18/17	2D 3D TSV
US9469627	3	3	HGNC:17890	Phenyloxadiazole derivatives as PGDS inhibitors	Sanofi	09/18/17	2D 3D TSV
US9434697	144	66	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	Eisai R&D Management Co., Ltd	09/18/17	2D 3D TSV
US9464103	12	12		Spirocyclic sulfones as gamma secretase inhibitors	Merck Sharp & Dohme Corp	09/18/17	2D 3D TSV
US9434727	247	112	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	Columbia University	09/18/17	2D 3D TSV
US9447038	205	203	HGNC:10637	Substituted B-amino acid derivatives as CXCR3 receptor antagonists	Sanofi	09/18/17	2D 3D TSV
US9452980	625	321		Substituted benzamides	Hoffmann-La Roche Inc	09/18/17	2D 3D TSV
US9447106	218	217	HGNC:1133	Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators	BeiGene, Ltd	09/18/17	2D 3D TSV
US9475795	111	107		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases	Takeda Pharmaceutical Co., Ltd	09/18/17	2D 3D TSV
US9457039	24	19		2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	09/11/17	2D 3D TSV
US9434725	762	199	HGNC:19310 HGNC:8987	5-azaindazole compounds and methods of use	F. Hoffmann-La Roche Inc	09/11/17	2D 3D TSV
US9458145	111	42		Benzimidazole derivatives as bromodomain inhibitors	Gilead Sciences Inc	09/11/17	2D 3D TSV
US9453034	72	36	HGNC:934 HGNC:933	C2-azaspiro iminothiazine dioxides as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	09/11/17	2D 3D TSV
US9458136	1	1	HGNC:2160	Crystalline forms and processes for the preparation of cannabinoid receptor modulators	Arena Pharmaceuticals Inc	09/11/17	2D 3D TSV
US9458135	60	30	HGNC:2592 HGNC:2591	Dihydroquinoline-2-one derivatives	Hoffmann-La Roche Inc	09/11/17	2D 3D TSV
US9464062	6	6	HGNC:5294	Disubstituted oxazolidin-2-ones 5-hydroxytryptamine receptor 2B activity modulators	Temple University	09/11/17	2D 3D TSV
US9458140	29	29		Furanone compounds as kinase inhibitors	Eternity Bioscience Inc.	09/11/17	2D 3D TSV
US9453038	42	34	HGNC:4195	Glucokinase activator compounds, compositions containing such compounds, and methods of treatment	Merck Sharp & Dohme Corp	09/11/17	2D 3D TSV
US9453048	38	17		IAP antagonists	Bristol-Myers Squibb Co.	09/11/17	2D 3D TSV
US9458105	10	10	HGNC:1133	Inhibitors of Bruton's tyrosine kinase	Hoffmann-La Roche Inc	09/11/17	2D 3D TSV
US9464073	16	4	HGNC:4852 HGNC:14064 HGNC:4854 HGNC:4853	Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors	Acetylon Pharmaceuticals Inc	09/11/17	2D 3D TSV
US9464081	23	23	HGNC:2771	Pyrrolidine derivatives and their use as complement pathway modulators	Novartis AG	09/11/17	2D 3D TSV
US9434711	709	701	HGNC:17961	Sulfonamides as TRPM8 modulators	Janssen Pharmaceutica NV	09/11/17	2D 3D TSV
US9463192	43	43	HGNC:8031	Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	09/11/17	2D 3D TSV
US9434719	783	471	HGNC:5382	3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH	Novartis AG	09/05/17	2D 3D TSV
US9453017	12	3	HGNC:9068 HGNC:9067	Antiviral therapies with phospholipase D inhibitors	Vanderbilt University	09/05/17	2D 3D TSV
US9447029	38	28	HGNC:2625 HGNC:1389	Fluorinated arylalkylaminocarboxamide derivatives	Newron Pharmaceuticals S.P.A.	09/05/17	2D 3D TSV
US9447090	34	34		Imidazopyridine compounds	Astellas Pharma Inc	09/05/17	2D 3D TSV
US9447085	33	17	HGNC:934 HGNC:933	Iminothiadiazine dioxides containing a thioamide, amidine, or amide oxime group as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	09/05/17	2D 3D TSV
US9446026	20	1	HGNC:6091 HGNC:12680 HGNC:11390 HGNC:8803 HGNC:3763 HGNC:11724 HGNC:4037 HGNC:6307 HGNC:8804 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3767 HGNC:3236 HGNC:9967 HGNC:3688 HGNC:3765	Ocular formulations for drug-delivery to the posterior segment of the eye	PanOptica, Inc.	09/05/17	2D 3D TSV
US9434733	75	71	HGNC:8795	PDE9 inhibitors with imidazo triazinone backbone	H. Lundbeck A/S	09/05/17	2D 3D TSV
US9447092	48	5	HGNC:11393 HGNC:6251 HGNC:11390 HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621 HGNC:2610 HGNC:3765	Pharmaceutically active compounds	Cancer Research Technology Limited	09/05/17	2D 3D TSV
US9447091	40	40	HGNC:3688	Protein kinase inhibitors	ORION CORPORATION	09/05/17	2D 3D TSV
US9447095	30	30	HGNC:8772	Pyrimidine derivatives as phosphodiesterase 10 inhibitors (PDE-10)	Palobiofarma, S.L.	09/05/17	2D 3D TSV
US9453018	22	8	HGNC:6371 HGNC:3529	Pyrimidinones as factor XIa inhibitors	Bristol-Myers Squibb Co.	09/05/17	2D 3D TSV
US9453021	17	17		Pyrimidodiazepinone compound	Kyowa Hakko Kirin Co., Ltd	09/05/17	2D 3D TSV
US9434724	377	84	HGNC:6251 HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621	Quinuclidines for modulating alpha 7 activity	ALPHARMAGEN, LLC	09/05/17	2D 3D TSV
US9453023	39	39		Substituted phenyl cycloalkyl pyrrolidine (piperidine) spirolactams and amides, preparation and therapeutic use thereof	Sanofi	09/05/17	2D 3D TSV
US9452985	8	8	HGNC:6893	Tau imaging probe	GE Healthcare Limited	09/05/17	2D 3D TSV
US9428508	324	161	HGNC:9611 HGNC:9612	2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as FAK/Pyk2 inhibitors	Centaurus BioPharma Co., Ltd	08/28/17	2D 3D TSV
US9446130	25	25	HGNC:1133	BTK inhibitors	Merck Sharp & Dohme Corp	08/28/17	2D 3D TSV
US9433609	144	20		Benzimidazole-imidazole derivatives	Janssen Ireland	08/28/17	2D 3D TSV
US9428514	208	104		Bromodomain inhibitors	AbbVie Inc	08/28/17	2D 3D TSV
US9446044	107	65	HGNC:3092 HGNC:3091	DYRK1 inhibitors and uses thereof	DIAXONHIT	08/28/17	2D 3D TSV
US9447132	2	2		Highly active nucleoside derivative for the treatment of HCV	Achillion Pharmaceuticals Inc	08/28/17	2D 3D TSV
US9428503	315	79	HGNC:882 HGNC:795 HGNC:8975 HGNC:3942	Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer	AstraZeneca AB	08/28/17	2D 3D TSV
US9428511	152	73	HGNC:6190 HGNC:6193	Imidazopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases	Bristol-Myers Squibb Co.	08/28/17	2D 3D TSV
US9434692	4	4		Pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	08/28/17	2D 3D TSV
US9433622	330	165	HGNC:11584 HGNC:14552	Pyrimidine compounds useful in the treatment of diseases mediated by IKKE and/or TBK1 mechanisms	Case Western Reserve University	08/28/17	2D 3D TSV
US9447057	29	29		Schiff bases of thiazoles: a new class of ureases inhibitors	TBA	08/28/17	2D 3D TSV
US9434690	357	143	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders	Bayer Pharma Aktiengesellschaft	08/28/17	2D 3D TSV
US9434693	45	45	HGNC:1403	Substituted pyrazoles as N-type calcium channel blockers	Janssen Pharmaceutica NV	08/28/17	2D 3D TSV
US9447114	29	23	HGNC:12337	Thieno- and furo[2,3-d]pyrimidine-2,4[1H,3H]-dione derivatives	Hydra Biosciences Inc	08/28/17	2D 3D TSV
US9428513	29	29		Triazolopyrazine	Boehringer Ingelheim International GmbH	08/28/17	2D 3D TSV
US9428505	22	17		Hydantoin derivative	Chugai Seiyaku Kabushiki Kaisha	08/24/17	2D 3D TSV
US9428469	30	29		Antiviral compounds	F. Hoffmann-La Roche Inc	08/22/17	2D 3D TSV
US9447055	2	2	HGNC:9600	α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof	Merck Serono	08/21/17	2D 3D TSV
US9428456	501	498	HGNC:23692	1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives	Actelion Pharmaceuticals Ltd	08/21/17	2D 3D TSV
US9428504	172	169	HGNC:8539	7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor	Bristol-Myers Squibb Co.	08/21/17	2D 3D TSV
US9428500	117	57	HGNC:427	Alpha-carbolines for the treatment of cancer	UNIVERSITA DEGLI STUDI DI MILANO—BICOCCA	08/21/17	2D 3D TSV
US9427428	138	20		Benzimidazole-imidazole derivatives	Janssen Ireland	08/21/17	2D 3D TSV
US9428501	53	19	HGNC:9377 HGNC:8975	Bicyclic nitrogen-containing aromatic heterocyclic amide compound	Astellas Pharma Inc	08/21/17	2D 3D TSV
US9446064	9	9		Combination therapy for treating cancer	Epizyme Inc	08/21/17	2D 3D TSV
US9428502	338	335	HGNC:3594	Heterocyclic modulators of lipid synthesis	3-V Biosciences, Inc.	08/21/17	2D 3D TSV
US9427440	69	27		Macrocyclic indole derivatives useful as hepatitis C virus inhibitors	Janssen Ireland	08/21/17	2D 3D TSV
US9428460	40	32		N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products	Bayer Pharma Aktiengesellschaft	08/21/17	2D 3D TSV
US9428478	66	41	HGNC:12805 HGNC:2578	Piperazine derivatives, compositions, and uses related thereto	Emory University	08/21/17	2D 3D TSV
US9428476	17	9	HGNC:934 HGNC:933	S-imino-S-oxo-iminothiadiazine compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	08/21/17	2D 3D TSV
US9428492	54	24	HGNC:2623	Secondary alcohol substituted triazoles as PDE10 inhibitors	Merck Sharp & Dohme Corp	08/21/17	2D 3D TSV
US9428491	12	10		Substituted azoles, antiviral active component, pharmaceutical composition, method for preparation and use thereof	TBA	08/21/17	2D 3D TSV
US9422293	771	377	HGNC:12716	Tetrahydro-pyrimidoazepines as modulators of TRPV1	Janssen Pharmaceutica NV	08/21/17	2D 3D TSV
US9422331	108	54		2-oxo-2,3,4,5-tetrahydro-1 H-benzo[B]diazepines and their use in the treatment of cancer	Hoffmann-La Roche Inc	08/14/17	2D 3D TSV
US9422332	92	47		Azaheterocycles as BIR2 and/or BIR3 inhibitors	Hoffmann-La Roche Inc	08/14/17	2D 3D TSV
US9428447	29	21	HGNC:14064 HGNC:4854	Bis-(aryl/heteroaryl)-methylene compounds, pharmaceutical compositions containing same and their use for treating cancer	The Royal Institution for the Advancement of Learning/McGill University	08/14/17	2D 3D TSV
US9415055	223	223	HGNC:8537	Cyclic amines	H. Lundbeck A/S	08/14/17	2D 3D TSV
US9422318	37	35	HGNC:3402	Epoxyeicosatrienoic acid analogs and methods of making and using the same	The Medical College of Wisconsin, Inc.	08/14/17	2D 3D TSV
US9427442	58	29	HGNC:5724	Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds	Bristol-Myers Squibb Co.	08/14/17	2D 3D TSV
US9422240	52	51	HGNC:1232	Partially saturated nitrogen-containing heterocyclic compound	Taisho Pharmaceutical Co., Ltd	08/14/17	2D 3D TSV
US9422255	40	20	HGNC:934 HGNC:933	S-imino-S-oxo-iminothiazine compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	08/14/17	2D 3D TSV
US9422299	205	46	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Substituted [1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Euroscreen SA	08/14/17	2D 3D TSV
US9416132	120	103	HGNC:6251	Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors	Tolero Pharmaceuticals Inc	08/14/17	2D 3D TSV
US9422235	171	95	HGNC:2160 HGNC:2159	Sulfonamide derivatives with therapeutic indications	Pharmos Corporation	08/14/17	2D 3D TSV
US9422290	38	36		Triazolopyridazine	Boehringer Ingelheim International GmbH	08/14/17	2D 3D TSV
US9422297	65	27	HGNC:6307 HGNC:8804 HGNC:12441 HGNC:3236	Tricyclic compounds having cytostatic and/or cytotoxic activity and methods of use thereof	Duquesne University of the Holy Ghost	08/14/17	2D 3D TSV
US9416129	244	120	HGNC:934 HGNC:2529 HGNC:933	Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use	Merck Sharp & Dohme Corp	08/14/17	2D 3D TSV
US9422277	170	83	HGNC:934 HGNC:933	Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use	Merck Sharp & Dohme Corp	08/14/17	2D 3D TSV
US9394331	44	30		2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections	Gilead Pharmasset LLC	08/07/17	2D 3D TSV
US9409892	368	183	HGNC:1232 HGNC:14660	4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors	FibroGen Inc	08/07/17	2D 3D TSV
US9416154	45	44		5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	08/07/17	2D 3D TSV
US9428465	17	15	HGNC:735	Acid ceramidase inhibitors and their use as medicaments	Fondazione Istituto Italiano Di Technologia	08/07/17	2D 3D TSV
US9409895	69	69	HGNC:3357	Autotaxin inhibitors	Novartis AG	08/07/17	2D 3D TSV
US9409908	443	216	HGNC:3551 HGNC:6371	Dihydropyridone p1 as factor XIa inhibitors	Bristol-Myers Squibb Co.	08/07/17	2D 3D TSV
US9409888	53	27		Dimeric compounds	Hoffmann-La Roche Inc	08/07/17	2D 3D TSV
US9422333	28	4		HCV protease inhibitors and uses thereof	Celgene Avilomics Research, Inc.	08/07/17	2D 3D TSV
US9409917	118	86	HGNC:8537	Heterocyclic amide derivatives as P2X7 receptor antagonists	Actelion Pharmaceuticals Ltd	08/07/17	2D 3D TSV
US9421177	72	36	HGNC:11240	Imidamide sphingosine kinase inhibitors	University of Virginia Patent Foundation	08/07/17	2D 3D TSV
US9409907	205	204	HGNC:12401	Inhibitor compounds	Cancer Research Technology Limited	08/07/17	2D 3D TSV
US9416123	85	16	HGNC:9617 HGNC:6307 HGNC:19297 HGNC:11283 HGNC:1097 HGNC:10020 HGNC:3236	Kinase modulators for the treatment of cancer	Synovo GmbH	08/07/17	2D 3D TSV
US9428466	9	5	HGNC:12805 HGNC:17989	Methods for reducing uric acid levels using barbiturate derivatives	TBA	08/07/17	2D 3D TSV
US9416139	72	34		Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof	Sunshine Lake Pharma Co., Ltd	08/07/17	2D 3D TSV
US9409915	90	90		Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators	Janssen Pharmaceutica NV	08/07/17	2D 3D TSV
US9422307	17	17	HGNC:9611	2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors	Korea Institute of Science and Technology	08/01/17	2D 3D TSV
US9422324	8	4	HGNC:3467 HGNC:3468	6-substituted demethyl-estradiol derivatives as selective ER-β agonists	Endece LLC	08/01/17	2D 3D TSV
US9422312	21	21	HGNC:9385	Azabenzimidazole derivatives	Boehringer Ingelheim International GmbH	08/01/17	2D 3D TSV
US9422273	40	5	HGNC:9591 HGNC:9594 HGNC:9593 HGNC:9596 HGNC:9595 HGNC:11608 HGNC:9600 HGNC:9602	Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response	Allergan Inc	08/01/17	2D 3D TSV
US9422243	55	19	HGNC:270 HGNC:272	3-phenyl-isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors	Nerviano Medical Sciences srl	07/31/17	2D 3D TSV
US9403813	270	135	HGNC:4849 HGNC:4848	Azetidine amide derivatives as orexin receptor antagonists	Actelion Pharmaceuticals Ltd	07/31/17	2D 3D TSV
US9403843	72	54	HGNC:1476	Cysteine protease inhibitors and uses thereof	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	07/31/17	2D 3D TSV
US9422263	19	10	HGNC:7029	Fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof	Bayer Pharma Aktiengesellschaft	07/31/17	2D 3D TSV
US9422261	11	11		Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof	PIERRE FABRE DERMO-COSMETIQUE	07/31/17	2D 3D TSV
US9422231	5	5		Method for inhibiting Trypanosoma cruzi	Howard University	07/31/17	2D 3D TSV
US9403808	195	105	HGNC:2160 HGNC:2159	Pyrazine derivatives	Hoffmann-La Roche Inc	07/31/17	2D 3D TSV
US9409882	96	48	HGNC:2537 HGNC:2545	Pyridine derivatives	Hoffmann-La Roche Inc	07/31/17	2D 3D TSV
US9409866	620	222	HGNC:2160 HGNC:2159	Pyridine-2-amides useful as CB2 agonists	Hoffmann-La Roche Inc	07/31/17	2D 3D TSV
US9409924	26	19	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	07/31/17	2D 3D TSV
US9403767	182	71	HGNC:8154 HGNC:8155 HGNC:8156	Substituted 4-aminocyclohexane derivatives	Gruenenthal GmbH	07/31/17	2D 3D TSV
US9403801	81	40	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11393 HGNC:12440 HGNC:3765	Substituted heteroaryl compounds and methods of use	CALITOR SCIENCES, LLC	07/31/17	2D 3D TSV
US9394309	198	170		Substituted phenylimidazopyrazoles and their use	Bayer Pharma Aktiengesellschaft	07/31/17	2D 3D TSV
US9416127	72	32		Triazole carboxamides and uses thereof	Hoffmann-La Roche Inc	07/31/17	2D 3D TSV
US9394311	136	134	HGNC:8772	Triazolo compounds as PDE10 inhibitors	Hoffmann-La Roche Inc	07/31/17	2D 3D TSV
US9403810	48	48		Carboxamide derivatives	Novartis AG	07/25/17	2D 3D TSV
US9409931	8	4	HGNC:9399	3-O-acyl-ingenol analogues	LEO LABORATORIES LIMITED	07/24/17	2D 3D TSV
US9408863	13	13		5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	07/24/17	2D 3D TSV
US9409845	22	22	HGNC:3236	Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof	PHARMAXYN LABORATORIES LTD.	07/24/17	2D 3D TSV
US9394297	934	430	HGNC:8987	Amides as pim inhibitors	Amgen Inc	07/24/17	2D 3D TSV
US9403846	28	25	HGNC:933	Carbocyclic- and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	07/24/17	2D 3D TSV
US9403833	17	16		Carboxamide derivatives	Novartis AG	07/24/17	2D 3D TSV
US9409900	4	4		Compound for increasing kinase active and application thereof	FUJIAN HAIXI PHARMACEUTICALS, INC.	07/24/17	2D 3D TSV
US9416126	394	366		Compounds inhibiting leucine-rich repeat kinase enzyme activity	Merck Sharp & Dohme Corp	07/24/17	2D 3D TSV
US9403803	15	10	HGNC:6307 HGNC:8804	Indole-3-carboxamides as kinase inhibitors	Allergan Inc	07/24/17	2D 3D TSV
US9403768	24	12		Indolines	Hoffmann-La Roche Inc	07/24/17	2D 3D TSV
US9409868	44	22		Inhibitors of rho associated protein kinases (ROCK) and methods of use	H. Lee Moffin Cancer Center and Research Institute, Inc.	07/24/17	2D 3D TSV
US9409858	37	19	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	07/24/17	2D 3D TSV
US9408850	74	37		Substituted indazole derivatives active as kinase inhibitors	Nerviano Medical Sciences srl	07/24/17	2D 3D TSV
US9403827	32	25		Substituted purinone compounds	Novartis AG	07/24/17	2D 3D TSV
US9403831	42	41	HGNC:7029	Triazolopyrazine derivative and use thereof	Korea Research Institute of Chemical Technology	07/24/17	2D 3D TSV
US9416103	25	11	HGNC:2160	Use of the aminoalkylindole JWH-073-M4 and related compounds as neutral CB1 receptor antagonists for the treatment of alcoholism, drug abuse, obesity, and obesity-related diseases	University of Arkansas	07/24/17	2D 3D TSV
US9394275	191	93	HGNC:286 HGNC:1952	Diamide compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity	Theravance Respiratory Company LLC	07/18/17	2D 3D TSV
US9394273	118	16	HGNC:9594 HGNC:9596 HGNC:9595 HGNC:11608	Therapeutic prostaglandin receptor agonists	Allergan Inc	07/18/17	2D 3D TSV
US9403797	2	2	HGNC:1925	5-(pyridin-2-yl-amino)-pyrazine-2-carbonitrile compounds and their therapeutic use	Cancer Research Technology Limited	07/17/17	2D 3D TSV
US9394291	20	10		Benzoxazinone amides as mineralocorticoid receptor modulators	AstraZeneca AB	07/17/17	2D 3D TSV
US9403774	6	6	HGNC:3529	Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors	Bristol-Myers Squibb Co.	07/17/17	2D 3D TSV
US9394285	186	177	HGNC:9385	Indole and indazole compounds that activate AMPK	Pfizer Inc	07/17/17	2D 3D TSV
US9394289	44	44		Inhibitors of c-fms kinase	Janssen Pharmaceutica NV	07/17/17	2D 3D TSV
US9403804	10	10		Inhibitors of c-fms kinase	Janssen Pharmaceutica NV	07/17/17	2D 3D TSV
US9388165	22	9	HGNC:8803 HGNC:3430 HGNC:6307 HGNC:8804 HGNC:5465 HGNC:11283 HGNC:1097 HGNC:76 HGNC:3689 HGNC:3236 HGNC:3688 HGNC:3765	Isoquinoline-5-carboxamide derivative having inhibitory activity for protein kinase	Hanmi Pharm. Co., Ltd	07/17/17	2D 3D TSV
US9402837	20	20	HGNC:4177	Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase	Amicus Therapeutics, Inc	07/17/17	2D 3D TSV
US9409887	14	5		Mutant-selective EGFR inhibitors and uses thereof	Celgene Avilomics Research, Inc.	07/17/17	2D 3D TSV
US9388210	17	13		Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same	Washington University	07/17/17	2D 3D TSV
US9394282	406	196	HGNC:6190 HGNC:6192	Pyrazole carboxamides as Janus kinase inhibitors	Merck Sharp & Dohme Corp	07/17/17	2D 3D TSV
US9394290	90	46	HGNC:2592 HGNC:2591	Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases	UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN	07/17/17	2D 3D TSV
US9394303	31	23		Small molecule inhibitors of MCL-1 and uses thereof	The Regents of the University of Michigan	07/17/17	2D 3D TSV
US9393232	171	122		Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones	BeiGene, Ltd	07/17/17	2D 3D TSV
US9394263	237	131		Substituted hetero-azepinones	F. Hoffmann-La Roche Inc	07/17/17	2D 3D TSV
US9394250	56	19	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor xia inhibitors for the treatment thromboembolic diseases	Ono Pharmaceutical Co., Ltd	07/17/17	2D 3D TSV
US9402842	12	12	HGNC:18884	Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors	Purdue Research Foundation	07/17/17	2D 3D TSV
US9394293	17	6	HGNC:12716	TRPV1 antagonists including dihydroxy substituent and uses thereof	Purdue Pharma LP	07/17/17	2D 3D TSV
US9394254	6	4		Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase	The University of Denver and Regis University	07/10/17	2D 3D TSV
US9403822	5	5	HGNC:990	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	07/10/17	2D 3D TSV
US9365589	82	37	HGNC:934 HGNC:933	C5, C6 oxacyclic-fused thiazine dioxide compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	07/10/17	2D 3D TSV
US9402878	2	2	HGNC:6251	Depsipeptide and uses thereof	NovoBiotic Pharmaceuticals, LLC	07/10/17	2D 3D TSV
US9388139	97	28	HGNC:9605 HGNC:8784 HGNC:8795 HGNC:8772 HGNC:8774 HGNC:8779 HGNC:9604 HGNC:8778	Derivatives of celeboxib, use thereof and preparation thereof	German University	07/10/17	2D 3D TSV
US9388149	69	25	HGNC:6026 HGNC:6027	Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases	Galderma Research & Development	07/10/17	2D 3D TSV
US9394307	6	5	HGNC:2637 HGNC:2623	Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation	ChemoCentryx, Inc.	07/10/17	2D 3D TSV
US9388197	76	75	HGNC:8537	Heterocyclic amide derivatives as P2X7 receptor antagonists	Actelion Pharmaceuticals Ltd	07/10/17	2D 3D TSV
US9388198	17	16	HGNC:8537	Heterocyclic amide derivatives as P2X7 receptor antagonists	Actelion Pharmaceuticals Ltd	07/10/17	2D 3D TSV
US9394304	18	18	HGNC:497	Imidazopyridine derivatives	Hoffmann-La Roche Inc	07/10/17	2D 3D TSV
US9365582	24	12		Macrocyclic inhibitors of hepatitis C virus	Janssen Ireland	07/10/17	2D 3D TSV
US9388176	119	87	HGNC:6307 HGNC:8804	Method of treating conditiions with kinase inhibitors	Allergan Inc	07/10/17	2D 3D TSV
US9365572	65	6	HGNC:9393 HGNC:17967 HGNC:10252 HGNC:16835 HGNC:3091 HGNC:10810 HGNC:391 HGNC:8816 HGNC:5465 HGNC:1460 HGNC:6871 HGNC:8975 HGNC:3688 HGNC:6876 HGNC:3765 HGNC:9380 HGNC:6192 HGNC:6193 HGNC:11393 HGNC:6307 HGNC:8804 HGNC:1771 HGNC:6342 HGNC:3236 HGNC:1925 HGNC:11283 HGNC:9376 HGNC:10432 HGNC:11724 HGNC:10434 HGNC:9407 HGNC:6735 HGNC:10436 HGNC:5960 HGNC:2452 HGNC:3385 HGNC:12858 HGNC:11406 HGNC:3942 HGNC:6896 HGNC:7029 HGNC:7745 HGNC:8591 HGNC:11491 HGNC:427 HGNC:76 HGNC:3657 HGNC:6886 HGNC:2444 HGNC:6524 HGNC:6887	PI3K and/or mTOR inhibitor	Xuanzhu Pharma Co., Ltd	07/10/17	2D 3D TSV
US9403799	14	2	HGNC:7029	Pyrimidinyl-pyridazinone derivatives for treating a disease which is influenced by inhibition of met kinase	Merck Patent GmbH	07/10/17	2D 3D TSV
US9388199	44	44	HGNC:2771	Pyrrolidine derivatives and their use as complement pathway modulators	Novartis AG	07/10/17	2D 3D TSV
US9388189	81	81	HGNC:8977	Pyrrolotriazinone derivatives as PI3K inhibitors	Almirall, S.A.	07/10/17	2D 3D TSV
US9388171	28	14	HGNC:10430	Serine/threonine kinase inhibitors	Genetech, Inc	07/10/17	2D 3D TSV
US9394276	16	16	HGNC:3529	Substituted 1,2,3,4-tetrahydro-2,6-naphthyridines as factor XIa inhibitors	Bristol-Myers Squibb Co.	07/10/17	2D 3D TSV
US9388181	15	7	HGNC:6307 HGNC:8804	Substituted 1,2,3,4-tetrahydropyrido[3,4-E] pyrrolo[1,2-A]pyrimidines as kinase	Allergan Inc	07/10/17	2D 3D TSV
US9388140	120	117	HGNC:12401	Substituted benzimidazoles	Bayer Intellectual Property GmbH	07/10/17	2D 3D TSV
US9388162	146	60	HGNC:8154 HGNC:8156	Substituted morphinans and the use thereof	Purdue Pharma LP	07/10/17	2D 3D TSV
US9388136	35	19	HGNC:6876	Tert-butyl N-[2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]-3,5-difluorophenyl}ethyl]-L-alaninate or a salt, hydrate or solvate thereof	Chroma Therapeutics Ltd	07/10/17	2D 3D TSV
USRE46024	22	22		Thyroid hormone analogs	Hoffmann-La Roche Inc	07/10/17	2D 3D TSV
US9365562	126	126		1,3 substituted azetidine PDE10 inhibitors	Merck Sharp & Dohme Corp	07/03/17	2D 3D TSV
US9364459	43	15	HGNC:6307 HGNC:4617 HGNC:3765	3-(indolyl)- or 3-(azaindolyl)- 4-arylmaleimide derivatives for use in the treatment of colon and gastric adenocarcinoma	Johannes Gutenberg-Universität Mainz	07/03/17	2D 3D TSV
US9365508	26	13	HGNC:10886 HGNC:14929	Aroyl thiourea derivatives	University Court of the University of St Andrews	07/03/17	2D 3D TSV
US9365534	43	19	HGNC:2160 HGNC:2159	Arylated camphenes, processes for their preparation and uses thereof	YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.	07/03/17	2D 3D TSV
US9365529	68	20	HGNC:195 HGNC:7173 HGNC:216 HGNC:7176 HGNC:7155 HGNC:188	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics	GALDERMA RESEARCH & DEVLOPMENT	07/03/17	2D 3D TSV
US9359371	77	34	HGNC:8773	Bicyclic substituted pyrimidine compounds	Xuanzhu Pharma Co., Ltd	07/03/17	2D 3D TSV
US9365511	26	26	HGNC:5184	Biphenyl-ethyl-pyrrolidine derivatives as histamine H3 receptor modulators for the treatment of cognitive disorders	Arena Pharmaceuticals Inc	07/03/17	2D 3D TSV
US9359372	60	29	HGNC:3023 HGNC:5286 HGNC:3020	Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	07/03/17	2D 3D TSV
US9359361	20	20	HGNC:15633	Immune system modulators	JANUS BIOTHERAPEUTICS, INC.	07/03/17	2D 3D TSV
US9365575	25	25	HGNC:6307	Kinase inhibitors	Allergan Inc	07/03/17	2D 3D TSV
US9365853	7	7		Matriptase inhibitors and uses thereof against orthomyxoviridae infections	TBA	07/03/17	2D 3D TSV
US9365502	18	18		Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors	Washington University	07/03/17	2D 3D TSV
US9365539	11	11	HGNC:9344	Prolylcarboxypeptidase inhibitors	Merck Sharp & Dohme Corp	07/03/17	2D 3D TSV
US9365576	279	238		Pyrrolopyrrolidinone compounds	Novartis AG	07/03/17	2D 3D TSV
US9388137	9	8	HGNC:10597	Quaternized amines as sodium channel blockers	Purdue Pharma LP	07/03/17	2D 3D TSV
US9394283	2	1	HGNC:3527	Salt form of a human histone methyltransferase EZH2 inhibitor	Epizyme Inc	07/03/17	2D 3D TSV
US9364482	134	67		Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	07/03/17	2D 3D TSV
US9394281	12	5	HGNC:6190 HGNC:6192 HGNC:11390 HGNC:3765	Substituted heteroaryl compounds and methods of use	CALITOR SCIENCES, LLC	07/03/17	2D 3D TSV
US9365546	8	2	HGNC:6887	Substituted pyridinone-pyridinyl compounds	Confluence Life Sciences Inc	07/03/17	2D 3D TSV
US9359399	71	36	HGNC:8154	Synthetic peptide amides	Cara Therapeutics, Inc.	07/03/17	2D 3D TSV
US9365563	228	137	HGNC:12716	TRPV1 antagonists including dihydroxy substituent and uses thereof	Purdue Pharma LP	07/03/17	2D 3D TSV
US9359338	366	240	HGNC:1097	Cyclopropanecarboxamido-substitute aromatic compounds as anti-tumor agents	CROWN BIOSCIENCE INC. (Taiwan)	06/27/17	2D 3D TSV
US9388160	4	2		Quinazoline derivatives as kinases inhibitors and methods of use thereof	Teligene Ltd	06/27/17	2D 3D TSV
US9388170	7	3		Substituted aminoquinazolines useful as kinases inhibitors	TBA	06/27/17	2D 3D TSV
US9353084	49	49	HGNC:933	2-amino 3,5,5-trifluoro-3,4,5,6-tetrahydropyridines as BACE1 inhibitors for treatment of Alzheimer's disease	H. Lundbeck A/S	06/26/17	2D 3D TSV
US9359337	12	12	HGNC:497	Acetamide derivatives	Hoffmann-La Roche Inc	06/26/17	2D 3D TSV
US9359341	11	2	HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2634 HGNC:2621	Aldehyde derivative of substitute oxazolidinones	WANBURY LTD.	06/26/17	2D 3D TSV
US9353089	180	82	HGNC:2529 HGNC:933 HGNC:2637 HGNC:2625 HGNC:2621	Compositions and methods for the treatment of malaria	Saint Louis University	06/26/17	2D 3D TSV
US9353101	64	64	HGNC:1869	Cyclic amine substituted heterocyclic CETP inhibitors	Merck Sharp & Dohme Corp	06/26/17	2D 3D TSV
US9359348	11	11		Cyclopropyl imidazopyridine PDE10 inhibitors	Merck Sharp & Dohme Corp	06/26/17	2D 3D TSV
US9365558	99	94	HGNC:7045	Dihydropyridinone MGAT2 inhibitors	Bristol-Myers Squibb Co.	06/26/17	2D 3D TSV
US9359339	19	19	HGNC:4192	Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use	Merck Sharp & Dohme Corp	06/26/17	2D 3D TSV
US9353093	63	26	HGNC:6307 HGNC:8800	Indole-1-carboxamides as kinase inhibitors	Allergan Inc	06/26/17	2D 3D TSV
US9353116	62	27	HGNC:18618	Methods and compositions for kinase inhibition	The Regents of the University of California	06/26/17	2D 3D TSV
US9353102	88	42	HGNC:3560 HGNC:3559	Non-annulated thiophenylamides	Hoffmann-La Roche Inc	06/26/17	2D 3D TSV
US9353104	130	130		Substituted pyridizinone derivatives as PDE10 inhibitors	Merck Sharp & Dohme Corp	06/26/17	2D 3D TSV
US9359345	12	12	HGNC:1133	Thiazole derivatives as inhibitors of Bruton's tyrosine kinase	Hoffmann-La Roche Inc	06/26/17	2D 3D TSV
US9393245	88	64	HGNC:11892	Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	06/26/17	2D 3D TSV
US9353061	28	7	HGNC:4852 HGNC:5006 HGNC:14064 HGNC:4853	3,5,N-trihydroxy-alkanamide and derivatives: method for making same and use thereof	National Taiwan University	06/19/17	2D 3D TSV
US9346829	31	29	HGNC:5297	5-HT3 receptor antagonists	Takeda Pharmaceutical Co., Ltd	06/19/17	2D 3D TSV
US9353081	132	46	HGNC:2592 HGNC:2591	Bicyclic dihydroquinoline-2-one derivatives	Hoffmann-La Roche Inc	06/19/17	2D 3D TSV
US9353075	66	55	HGNC:736	Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA)	University of California	06/19/17	2D 3D TSV
US9359301	14	6		Ethynyl derivatives	Hoffmann-La Roche Inc	06/19/17	2D 3D TSV
US9346814	250	49	HGNC:18648 HGNC:3009 HGNC:9358 HGNC:14892	FAP inhibitors	Universiteit Antwerp	06/19/17	2D 3D TSV
US9346821	66	33	HGNC:9490 HGNC:9475	Heterocyclic carboxylic acid ester derivative	Ajinomoto Co. Inc	06/19/17	2D 3D TSV
US9353090	331	323		Heterocyclic carboxylic acids as activators of soluble guanylate cyclase	Boehringer Ingelheim International GmbH	06/19/17	2D 3D TSV
US9351965	152	123		Indazole derivatives useful as ERK inhibitors	Merck Sharp & Dohme Corp	06/19/17	2D 3D TSV
US9359293	24	4	HGNC:14935 HGNC:14934 HGNC:10886 HGNC:14933 HGNC:14929 HGNC:14931	Methods of treatment using modulators of SIRT2	Cornell University	06/19/17	2D 3D TSV
US9346786	123	122	HGNC:11528	Pyrrolidine compounds	Hoffmann-La Roche Inc	06/19/17	2D 3D TSV
US9353066	228	225	HGNC:11491	Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors	Merck Sharp & Dohme Corp	06/19/17	2D 3D TSV
US9359330	25	23	HGNC:10597	Substituted piperidines as sodium channel blockers	Purdue Pharma LP	06/19/17	2D 3D TSV
US9346815	934	465	HGNC:6190 HGNC:6192	5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof	Genentech Inc	06/12/17	2D 3D TSV
US9345742	42	42	HGNC:2529	Aminostatin derivatives for the treatment of arthrosis	Merck Patent GmbH	06/12/17	2D 3D TSV
US9346770	29	10	HGNC:9232 HGNC:9235 HGNC:9236	Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses	Zhejiang Hisun Pharmaceutical Co., Ltd	06/12/17	2D 3D TSV
US9353067	3	3		Heterocyclic compounds and uses thereof in the treatment of sexual disorders	ATIR Holding S.A.	06/12/17	2D 3D TSV
US9353115	11	11	HGNC:15633	Immune system modulators	JANUS BIOTHERAPEUTICS, INC.	06/12/17	2D 3D TSV
US9353083	4	2	HGNC:6932 HGNC:6929	Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics	Galderma Research & Development	06/12/17	2D 3D TSV
US9358227	12	7	HGNC:3236	Pharmaceutical uses of 6-amino quinazoline or 3-cyano quinoline derivatives	Jiangsu Hengrui Medicine Co., Ltd.	06/12/17	2D 3D TSV
US9346839	11	9	HGNC:4800	Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease	University of Kansas	06/12/17	2D 3D TSV
US9351973	15	9	HGNC:2592 HGNC:2591	Pyrazolopyridyl compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	06/12/17	2D 3D TSV
US9346794	85	64	HGNC:3309	Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	06/12/17	2D 3D TSV
US9346795	186	93	HGNC:992 HGNC:990	Substituted sulfonamides useful as antiapoptotic Bcl inhibitors	Bristol-Myers Squibb Co.	06/12/17	2D 3D TSV
US9353113	13	13	HGNC:3357	Tetrahydrocarboline derivative	Ono Pharmaceutical Co., Ltd	06/12/17	2D 3D TSV
US9346827	11	10	HGNC:933	5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use	Amgen Inc	06/05/17	2D 3D TSV
US9346782	60	16		Alkyl linked quinolinyl modulators of RORγt	Janssen Pharmaceutica NV	06/05/17	2D 3D TSV
US9346818	42	39		Benzodioxole derivative and preparation method and use thereof	Zhejiang Hisun Pharmaceutical Co., Ltd	06/05/17	2D 3D TSV
US9345700	53	53	HGNC:6943	Compositions and methods useful for treating diseases	Eutropics Pharmaceuticals, Inc.	06/05/17	2D 3D TSV
US9346798	678	258	HGNC:10593 HGNC:10597	Dihydrobenzoxazine and tetrahydroquinoxaline sodium channel inhibitors	Amgen Inc	06/05/17	2D 3D TSV
US9346803	44	11	HGNC:387 HGNC:384 HGNC:385 HGNC:386	Indomethacin analogs for the treatment of castrate-resistant prostate cancer	Vanderbilt University	06/05/17	2D 3D TSV
US9340574	25	3	HGNC:16077 HGNC:9671 HGNC:9670 HGNC:9673 HGNC:9650 HGNC:3069 HGNC:9642 HGNC:9675 HGNC:9652 HGNC:9644 HGNC:9655 HGNC:9665 HGNC:9646 HGNC:9656 HGNC:9645 HGNC:9659 HGNC:9658 HGNC:9669	Inhibitors of protein tyrosine phosphatases	Indiana University Research and Technology Corporation	06/05/17	2D 3D TSV
US9340549	193	178		Oxazolidinone compounds and derivatives thereof	Amgen Inc	06/05/17	2D 3D TSV
US9346787	28	14	HGNC:11393 HGNC:11390	Piperidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	06/05/17	2D 3D TSV
US9339501	54	50	HGNC:2593	17a-hydroxylase/C17,20-lyase inhibitors	Novartis AG	05/31/17	2D 3D TSV
US9346797	14	12	HGNC:933	2-amino 6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	05/31/17	2D 3D TSV
US9340500	154	129	HGNC:18083	Aromatic heterocyclic derivative having TRPV4-inhibiting activity	Shionogi & Co., Ltd	05/31/17	2D 3D TSV
US9340537	173	102		Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1	NOVATIS AG	05/31/17	2D 3D TSV
US9334269	337	327	HGNC:10597	Carboxamides as inhibitors of voltage-gated sodium channels	Amgen Inc	05/31/17	2D 3D TSV
US9346793	15	15	HGNC:3827	Hydroxylated aminotriazole derivatives as ALX receptor agonists	Actelion Pharmaceuticals Ltd	05/31/17	2D 3D TSV
US9340517	531	489	HGNC:6932 HGNC:6933 HGNC:6929 HGNC:6931	Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor	Mimetica PTY LTD	05/31/17	2D 3D TSV
US9334286	108	107	HGNC:12401	Pharmacologically active compounds	Cancer Research Technology Limited	05/31/17	2D 3D TSV
US9340530	84	76	HGNC:3537	Preparation and use of bicyclic himbacine derivatives as PAR-1 receptor antagonists	Merck Sharp & Dohme Corp	05/31/17	2D 3D TSV
US9340507	111	109	HGNC:3309	Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	05/31/17	2D 3D TSV
US9353062	2	2	HGNC:1133	Substituted quinolines as bruton's tyrosine kinases inhibitors	HangzhouDeRenYuCheng Biotechnology Ltd	05/31/17	2D 3D TSV
US9334290	152	60	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Co.	05/31/17	2D 3D TSV
US9340510	245	245	HGNC:85	Tetrahydroisoquinoline derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	05/31/17	2D 3D TSV
US9346822	4	2	HGNC:4421	Thienopyrimidine compounds and use thereof	Takeda Pharmaceutical Co., Ltd	05/31/17	2D 3D TSV
US9340506	38	34	HGNC:4195	Acetamide derivatives as glucokinase activators, their process and medicinal applications	Advinus Therapeutics Ltd	05/22/17	2D 3D TSV
US9340573	28	14		Azaindolines	Hoffmann-La Roche Inc	05/22/17	2D 3D TSV
US9340555	180	69	HGNC:3763 HGNC:6307	Compounds as tyrosine kinase modulators	Allergan Inc	05/22/17	2D 3D TSV
US9345793	20	20	HGNC:6156	Compounds for binding to the platelet specific glycoprotein IIB/IIIA and their use for imaging of thrombi	PIRAMAL IMAGING SA	05/22/17	2D 3D TSV
US9334279	129	65		Hepatitis C virus inhibitors	Bristol-Myers Squibb Co.	05/22/17	2D 3D TSV
US9345740	24	12		IAP antagonists	Bristol-Myers Squibb Co.	05/22/17	2D 3D TSV
US9340521	130	65	HGNC:11037 HGNC:11036	Method for dual inhibition of SGLT1 and SGLT2 using diphenylmethane derivatives	Green Cross Corporation	05/22/17	2D 3D TSV
US9340542	20	7	HGNC:8154 HGNC:8156	Propellane-based compounds and the use thereof	Purdue Pharma LP	05/22/17	2D 3D TSV
US9340504	6	6	HGNC:10597	Pyridine and piperidine derivatives as novel sodium channel blockers	Purdue Pharma LP	05/22/17	2D 3D TSV
US9346810	249	144		Pyrrolopyrimidine compounds and uses thereof	Hutchison MediPharma Limited	05/22/17	2D 3D TSV
US9334288	34	9	HGNC:4696	Selective β-glucuronidase inhibitors as a treatment for side effects of camptothecin antineoplastic agents	University of North Carolina at Chapel Hill	05/22/17	2D 3D TSV
US9345789	13	5	HGNC:9472 HGNC:2527 HGNC:1504 HGNC:2537	Specific inhibitors and active site probes for legumain	The Board of Trustees of the Leland Stanford Junior University	05/22/17	2D 3D TSV
US9328099	1336	661	HGNC:6190 HGNC:6192	Cyanomethylpyrazole carboxamides as janus kinase inhibitors	Merck Sharp & Dohme Corp	05/18/17	2D 3D TSV
US9333195	34	34	HGNC:1952	Quinuclidine derivatives and medicinal compositions containing the same	Almirall, S.A.	05/18/17	2D 3D TSV
US9334268	25	13	HGNC:15631 HGNC:15632	4-amino-imidazoquinoline compounds	Hoffman-La Roche Inc	05/15/17	2D 3D TSV
US9340534	4	1	HGNC:9594 HGNC:9596	Compounds and methods for treating ocular diseases	Allergan Inc	05/15/17	2D 3D TSV
US9328106	297	284		Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	Genentech Inc	05/15/17	2D 3D TSV
US9339486	15	4	HGNC:2160 HGNC:2159	Heterocyclic modulators of cannabinoid receptors	The Cleveland Clinic Foundation	05/15/17	2D 3D TSV
US9333217	10	2	HGNC:3527	Inhibitors of human EZH2, and methods of use thereof	Epizyme Inc	05/15/17	2D 3D TSV
US9333205	6	3	HGNC:3255 HGNC:12401	Isoxazolo-quinazolines as modulators of protein kinase activity	Nerviano Medical Sciences srl	05/15/17	2D 3D TSV
US9333199	13	7	HGNC:17383 HGNC:5182	Methods of treatment of histamine H-4 receptor-related pruritus associated with nerve disorders	BRIDGE PHARMA, INC.	05/15/17	2D 3D TSV
US9340511	7	7	HGNC:1232	Process for making isoquinoline compounds	FibroGen Inc	05/15/17	2D 3D TSV
US9334271	32	32	HGNC:3942	Purine derivatives and their use in the treatment of disease	Novarits AG	05/15/17	2D 3D TSV
US9321790	119	119	HGNC:8979	Pyrimidinone derivatives as antimalarial agents	Sanofi	05/15/17	2D 3D TSV
US9334278	38	38		Pyrrolo[2,3-B]pyrazines as SYK inhibitors	Hoffmann-La Roche Inc	05/15/17	2D 3D TSV
US9328096	800	794		Tropomyosin-related kinase inhibitors	Pfizer Inc	05/15/17	2D 3D TSV
US9328120	34	28		6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders	Boehringer Ingelheim International GmbH	05/08/17	2D 3D TSV
US9321791	46	46	HGNC:3009	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions	Boehringer Ingelheim International GmbH	05/08/17	2D 3D TSV
US9326978	16	5	HGNC:268 HGNC:262 HGNC:263	A3 adenosine receptor allosteric modulators	The United States of America, Represented by the Secretary, Dept. of Health and Human Services	05/08/17	2D 3D TSV
US9321760	243	242	HGNC:10436	Aminopyrimidine derivatives for use as modulators of kinase activity	Merck Patent GmbH	05/08/17	2D 3D TSV
US9333197	9	9	HGNC:2595 HGNC:2637 HGNC:2615 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2621	Apoptosis signal-regulating kinase inhibitor	Gilead Sciences Inc	05/08/17	2D 3D TSV
US9321756	823	293	HGNC:19310 HGNC:8987	Azole compounds as PIM inhibitors	Amgen Inc	05/08/17	2D 3D TSV
US9328124	3	3		BACE inhibitors	Eli Lilly and Company	05/08/17	2D 3D TSV
US9321773	21	7	HGNC:8979 HGNC:8978 HGNC:8977	Compounds	Respivert Ltd	05/08/17	2D 3D TSV
US9328070	8	5		Ethynyl derivatives	Hoffmann-La Roche Inc	05/08/17	2D 3D TSV
US9328118	159	123	HGNC:2545	Nitrogen-containing bicyclic aromatic heterocyclic compound	Astellas Pharma Inc	05/08/17	2D 3D TSV
US9328123	5	4		Rotenone derivatives and a use thereof	Korea Atomic Energy Research Institute	05/08/17	2D 3D TSV
US9328111	39	18	HGNC:270 HGNC:272 HGNC:15677	Substituted cycloocta[5,6]pyrido[4,3,2-de]phthalazines as PARP inhibitors	BeiGene, Ltd	05/08/17	2D 3D TSV
US9328112	193	193	HGNC:1780	Tetracyclic CDK9 kinase inhibitors	AbbVie Inc	05/03/17	2D 3D TSV
US9315520	135	115	HGNC:6251 HGNC:2625	2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides	Pfizer Inc	05/01/17	2D 3D TSV
US9321748	59	30		Aminopyridine derived compounds as LRRK2 inhibitors	H. Lundbeck A/S	05/01/17	2D 3D TSV
US9321728	33	33	HGNC:2843	Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredient	Korea Research Institute of Chemical Technology	05/01/17	2D 3D TSV
US9320741	14	7	HGNC:13575	Compositions and methods for treating neoplasia, inflammatory disease and other disorders	Dana-Farber Cancer Institute Inc	05/01/17	2D 3D TSV
US9321743	25	25		Compositions and methods of inhibiting N-acylethanolamine-hydrolyzing acid amidase	University of California	05/01/17	2D 3D TSV
US9321766	10	5	HGNC:6307 HGNC:8804	Kinase inhibitors	Allergan Inc	05/01/17	2D 3D TSV
US9321738	28	14	HGNC:3166 HGNC:14298	N-alkyltriazole compounds as LPAR antagonists	Hoffman-La Roche Inc	05/01/17	2D 3D TSV
US9321752	10	10	HGNC:6893	Pyrazole derivative	GREEN TECH CO., LTD.	05/01/17	2D 3D TSV
US9321750	5	5		ROR modulators and their uses	INNOV17 LLC	05/01/17	2D 3D TSV
US9320722	81	55	HGNC:402 HGNC:404 HGNC:405	Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methods	Indiana University Research and Technology Corporation	05/01/17	2D 3D TSV
US9320734	110	44		Small molecule inhibitors of the pleckstrin homology domain and methods for using same	The University of Texas System	05/01/17	2D 3D TSV
US20160326143	65	64	HGNC:6719	Compounds and uses	AstraZeneca AB	04/27/17	2D 3D TSV
US9320732	21	20	HGNC:6059	1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase	Incyte Corporation	04/24/17	2D 3D TSV
US9315514	32	9	HGNC:8154 HGNC:8156	1,3-dioxanomorphides and 1,3-dioxanocodides	Rhodes Technologies	04/24/17	2D 3D TSV
US9321747	21	7	HGNC:1869	Acid addition salt of substituted pyridine compound	Daiichi Sankyo Company, Limited	04/24/17	2D 3D TSV
US9315498	174	173		Arlethynyl derivatives	Hoffman-La Roche Inc	04/24/17	2D 3D TSV
US9315500	26	26		Bicyclic heteroaryl cycloalkyldiamine derivatives	Novartis AG	04/24/17	2D 3D TSV
US9315489	98	80		Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1	Novartis AG	04/24/17	2D 3D TSV
US9315499	41	41		Cytomegalovirus inhibitor compounds	Boehringer Ingelheim International GmbH	04/24/17	2D 3D TSV
US9315519	6	6	HGNC:3529	Guanidine substituted tetrahydroisoquinoline compounds as factor XIa inhibitors	Bristol-Myers Squibb Co.	04/24/17	2D 3D TSV
US9315518	40	25	HGNC:4594	Imidazopyridin-2-one derivatives	Merck Sharp & Dohme Corp	04/24/17	2D 3D TSV
US9321721	8	7	HGNC:6307	Kinase inhibitors	Allergan Inc	04/24/17	2D 3D TSV
US9315493	18	18		Phenylpyridine derivative and drug containing same	KOWA COMPANY, LTD.	04/24/17	2D 3D TSV
US9315491	129	129	HGNC:3942	Pyrimidine compounds as mTOR and PI3K inhibitors	Development Center for Biotechnology	04/24/17	2D 3D TSV
US9320737	32	32		Substituted imidazopyridazines	Bayer Intellectual Property GmbH	04/24/17	2D 3D TSV
US9315508	3	3	HGNC:3009	Treating diabetes with dipeptidyl peptidase-IV inhibitors	Merck Sharp & Dohme Corp	04/24/17	2D 3D TSV
US9303017	131	12		2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof	Georgetown University	04/10/17	2D 3D TSV
US9303045	162	153	HGNC:5297	5-HT3 receptor antagonists	Takeda Pharmaceutical Co., Ltd	04/10/17	2D 3D TSV
US9303025	407	404	HGNC:990	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	04/10/17	2D 3D TSV
US9314468	140	122	HGNC:2561 HGNC:6251	Chemokine receptor modulators	Altiris Therapeutics, Inc.	04/10/17	2D 3D TSV
US9314464	22	22	HGNC:1097	Compounds and compositions as protein kinase inhibitors	Novartis AG	04/10/17	2D 3D TSV
US9315463	30	15	HGNC:286 HGNC:1952	Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities	Almirall, S.A.	04/10/17	2D 3D TSV
US9303015	151	44		Heteroaryl linked quinolinyl modulators of RORγt	Janssen Pharmaceutica NV	04/10/17	2D 3D TSV
US9315492	29	19	HGNC:3165	Heterocyclic group contained amino-methanol derivative, and salt, synthetic method and use thereof	Beijing Foreland Biopharma Co., Ltd.	04/10/17	2D 3D TSV
US9315438	10	5	HGNC:11037 HGNC:11036	Optically pure benzyl-4-chlorophenyl-C-glucoside derivative	Xuanzhu Pharma Co., Ltd	04/10/17	2D 3D TSV
US9303023	145	145	HGNC:4849	Pyrazole and imidazole derivatives useful as orexin antagonists	Actelion Pharmaceuticals Ltd	04/10/17	2D 3D TSV
US9303012	304	152	HGNC:2160 HGNC:2159	Pyridine-2-amides useful as CB2 agonists	Hoffman-La Roche Inc	04/10/17	2D 3D TSV
US9303035	36	34		Substituted pyrazino[1′,2′:1,2]pyrrolo[3,4-d]pyrimidines, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,4]oxazines and pyrimido[4′,5′:3,4]pyrrolo[1,2-d][1,4]oxazepines for inhibiting the CFTR channel	Novartis AG	04/10/17	2D 3D TSV
US9284322	30	16		Nicotinic receptor compounds	Research Triangle Institute	04/04/17	2D 3D TSV
US9296759	188	93	HGNC:2529 HGNC:933	Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use	Amgen Inc	04/03/17	2D 3D TSV
US9290488	165	39	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Azetidine-substituted quinoxalines as opioid receptor like-1 modulators	Purdue Pharma LP	04/03/17	2D 3D TSV
US9271961	119	27	HGNC:9605 HGNC:381 HGNC:382 HGNC:387 HGNC:384 HGNC:385 HGNC:9604 HGNC:386	Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof	University of Pennsylvania	04/03/17	2D 3D TSV
US9296741	698	348		Bromodomain inhibitors	AbbVie Inc	04/03/17	2D 3D TSV
US9296708	17	17	HGNC:2843	Chimeric small molecules for the recruitment of antibodies to cancer cells	Yale University	04/03/17	2D 3D TSV
US9302996	148	145	HGNC:2843	Continuous arycyclic compound	Mitsubishi Tanabe Pharma Corporation	04/03/17	2D 3D TSV
US9278100	149	25	HGNC:6193 HGNC:6171 HGNC:11491 HGNC:11283 HGNC:12841 HGNC:9617 HGNC:3432 HGNC:4840 HGNC:6735 HGNC:3697 HGNC:4037 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:76 HGNC:11719 HGNC:3236 HGNC:2444 HGNC:6524 HGNC:3655	Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors	Pharmacyclics LLC	04/03/17	2D 3D TSV
US9290476	160	94		Methylene linked quinolinyl modulators of RORγt	Janssen Pharmaceutica NV	04/03/17	2D 3D TSV
US9271963	95	27	HGNC:2594 HGNC:2592 HGNC:2593 HGNC:2591	Selective inhibitors of human corticosteroid synthases	Universitat des Saarlandes	04/03/17	2D 3D TSV
US9278925	146	10		Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one	Bayer Intellectual Property GmbH	04/03/17	2D 3D TSV
US9302986	97	26	HGNC:6834 HGNC:80 HGNC:550	Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof	Boehringer Ingelheim International GmbH	04/03/17	2D 3D TSV
US9303033	2239	1176	HGNC:2460 HGNC:2457	Pyrazolopyrimidines and related heterocycles as CK2 inhibitors	SENHWA BIOSCIENCES, INC.	03/30/17	2D 3D TSV
US9302985	17	17		Benzyl sulfonamide derivatives as RORc modulators	Genentech Inc	03/21/17	2D 3D TSV
US9212182	776	650	HGNC:10593 HGNC:10597	Bicyclic sulfonamide compounds as sodium channel inhibitors	Amgen Inc	03/21/17	2D 3D TSV
US9296681	36	12	HGNC:11050 HGNC:11048 HGNC:11049	Cycloalkylmethylamines	Reviva Pharmaceuticals Inc	03/21/17	2D 3D TSV
US9289400	6	2	HGNC:11050 HGNC:11048 HGNC:11049	D3 dopamine receptor agonists to treat dyskinesia in parkinson's disease	Drexel University	03/21/17	2D 3D TSV
US9284333	390	363	HGNC:6251 HGNC:6278	Fused pyrroledicarboxamides and their use as pharmaceuticals	Sanofi	03/21/17	2D 3D TSV
US9249087	156	50	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:1014 HGNC:4853 HGNC:18128	HDAC inhibitors and therapeutic methods using the same	University of Illinois	03/21/17	2D 3D TSV
US9290501	16	10		Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase	Albert Einstein College of Medicine, Inc	03/21/17	2D 3D TSV
US9296757	92	89	HGNC:4626	Substituted benzothienopyrimidines	Bayer Pharma Aktiengesellschaft	03/21/17	2D 3D TSV
US9260435	16	8	HGNC:391 HGNC:392	Substituted imidazopyrazines as Akt kinase inhibitors	Bayer Pharma Aktiengesellschaft	03/21/17	2D 3D TSV
US9303018	23	23	HGNC:6710	Inhibitors of leukotriene production	Boehringer Ingelheim International GmbH	03/13/17	2D 3D TSV
US9302989	1657	1518	HGNC:30092 HGNC:10252	NAMPT and rock inhibitors	AbbVie Inc	03/13/17	2D 3D TSV
US9303019	12	6	HGNC:283 HGNC:18006	Amino-pyrroline derivatives, and use thereof in the prevention and/or treatment of metabolic syndrome	Universite de Strasbourg	03/06/17	2D 3D TSV
US9296745	236	213	HGNC:16940	Diacylglycerol acyltransferase 2 inhibitors	Pfizer Inc	03/06/17	2D 3D TSV
US9296734	722	242	HGNC:2529 HGNC:933	Perfluorinated 5,6-dihydro-4H-1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use	Amgen Inc	03/06/17	2D 3D TSV
US9296736	497	405		Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer	Amgen Inc	03/06/17	2D 3D TSV
US9296748	113	112		Pyridinones	Boehringer Ingelheim International GmbH	03/06/17	2D 3D TSV
US9302981	6	2	HGNC:11050 HGNC:11048 HGNC:11049	Synthesis, methods of using, and compositions of cycloalkylmethylamines	Reviva Pharmaceuticals Inc	03/06/17	2D 3D TSV
US9303005	4	4	HGNC:2457	Use of dibenzofuranone derivatives to inhibit kinases	TBA	03/06/17	2D 3D TSV
US9296747	30	17	HGNC:6307 HGNC:8804	Piperidylpyrimidine derivatives as modulators of protein kinase inhibitors and of vascular endothelial growth factor receptor 2	Allergan Inc	02/28/17	2D 3D TSV
US9296703	2	2	HGNC:1133	Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors	University of Utah Research Foundation	02/28/17	2D 3D TSV
US9296728	26	26		Therapeutic compounds	Regents of the University of Minnesota	02/28/17	2D 3D TSV
US9284330	29	29	HGNC:108	1,4-dihydro-naphthyridine derivative and pharmaceutical composition and use thereof	Jiangsu Simovay Pharmaceutical Co., Ltd.	02/27/17	2D 3D TSV
US9296693	133	66	HGNC:3402	Acyl piperidine inhibitors of soluble epoxide hydrolase	The Regents of the University of California	02/27/17	2D 3D TSV
US9284319	34	18	HGNC:4626	Heterocyclyl aminoimidazopyridazines	Bayer Intellectual Property GmbH	02/27/17	2D 3D TSV
US9283222	773	725	HGNC:270	Inhibitors of poly(ADP-ribose)polymerase	AbbVie Inc	02/27/17	2D 3D TSV
US9295672	37	3	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:2637 HGNC:2615 HGNC:268 HGNC:2625 HGNC:12440 HGNC:2622 HGNC:2623 HGNC:2621	Optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof	Ambit Biosciences Corporation	02/27/17	2D 3D TSV
US9278978	83	42		6-Alkynyl Pyridine	Boehringer Ingelheim International GmbH	02/21/17	2D 3D TSV
US9278976	8	8	HGNC:3009	Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes	Merck Sharp & Dohme Corp	02/21/17	2D 3D TSV
US9278981	551	297	HGNC:76	Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1	Novartis AG	02/21/17	2D 3D TSV
US9284302	4	4		Cyclobutyl benzimidazoles as PDE 10 inhibitors	Merck Sharp & Dohme Corp	02/21/17	2D 3D TSV
US9278968	106	106		Imidazopyridine compounds	Astellas Pharma Inc	02/21/17	2D 3D TSV
US9284284	64	32	HGNC:934 HGNC:933	Oxazine derivatives and their use in the treatment of disease	Novartis AG	02/21/17	2D 3D TSV
US9296775	3	1	HGNC:11037 HGNC:11036	Pyrazole compounds	Eli Lilly and Company	02/21/17	2D 3D TSV
US9284298	8	6	HGNC:6192 HGNC:8987	Pyrazolyl-pyrimidine derivatives as kinase inhibitors	Nerviano Medical Sciences srl	02/21/17	2D 3D TSV
US9283225	2	2		Pyrido-pyrimidine derivatives	Merck Patent GmbH	02/21/17	2D 3D TSV
US9284299	58	25		Substituted 1H-indazol-1-ol analogs as inhibitors of beta catenin/Tcf protein-protein interactions	University of Utah Research Foundation	02/21/17	2D 3D TSV
US9284317	29	29	HGNC:12401	Substituted imidazo[1,2-a]pyrazines as MPS-1 inhibitors	Bayer Intellectual Property GmbH	02/21/17	2D 3D TSV
US9284315	32	16	HGNC:8975 HGNC:3942	Three-ring PI3K and/or mTOR inhibitor	ZUANZHU PHARMA CO., LTD.	02/21/17	2D 3D TSV
US9290517	25	25		Azabenzimidazole hexahydrofuro[3,2-b]furan derivatives	Merck Sharp & Dohme Corp	02/14/17	2D 3D TSV
US9278963	124	31	HGNC:4852 HGNC:14064 HGNC:4854 HGNC:4853	Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors	Acetylon Pharmaceuticals Inc	02/14/17	2D 3D TSV
US9278960	315	290	HGNC:4594	Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use	Merck Sharp & Dohme Corp	02/14/17	2D 3D TSV
US9278093	8	4	HGNC:2592 HGNC:2591	Aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	02/13/17	2D 3D TSV
US9278953	14	14	HGNC:9595	Antagonists of prostaglandin EP3 receptor	Pfizer Inc	02/13/17	2D 3D TSV
US9278930	32	16	HGNC:12680	Methods for increasing the stabilization of hypoxia inducible factor-α	Aerpio Therapeutics Inc	02/13/17	2D 3D TSV
US9278944	131	128	HGNC:9958	Nitrogen-containing saturated heterocyclic compound	Mitsubishi Tanabe Pharma Corporation	02/13/17	2D 3D TSV
US8772490	5	4		Optically active diazabicyclooctane derivatives and process for preparing the same	Meiji Seika Pharma Co., Ltd	02/13/17	2D 3D TSV
US9278954	172	149		Pyrrolidine derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	02/13/17	2D 3D TSV
US9278914	5	1	HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621	SARMs and method of use thereof	University of Tennessee Research Foundation	02/13/17	2D 3D TSV
US9278918	32	16	HGNC:3560 HGNC:3559	Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors	Hoffmann-La Roche Inc	02/13/17	2D 3D TSV
US9290482	8	8		Amino-substituted imidazopyridazines	Bayer Pharma Aktiengesellschaft	02/06/17	2D 3D TSV
US9290490	33	33	HGNC:11491	Aminopyrimidines as Syk inhibitors	Merck Sharp & Dohme Corp	02/06/17	2D 3D TSV
US9290507	137	137	HGNC:1097	B-RAF kinase inhibitors	Boehringer Ingelheim International GmbH	02/06/17	2D 3D TSV
US9290481	13	13		Monocyclic heteroaryl cycloalkyldiamine derivatives	Novartis AG	02/06/17	2D 3D TSV
US9290485	183	182	HGNC:6371	N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides	Novartis AG	02/06/17	2D 3D TSV
US9290487	74	74	HGNC:4706	Pharmaceutical composition for treating diabetes	Ajinomoto Co. Inc	02/06/17	2D 3D TSV
US9290459	353	270	HGNC:3309 HGNC:2622 HGNC:2623 HGNC:2621	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	02/06/17	2D 3D TSV
US9290457	215	211	HGNC:3309	Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	02/06/17	2D 3D TSV
US9290505	22	11	HGNC:1692 HGNC:11491	Substituted imidazo[1,2-a]pyrazines as Syk inhibitors	Gilead Sciences Inc	02/06/17	2D 3D TSV
US9247759	464	422	HGNC:14915 HGNC:14920	Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof	Senomyx Inc	02/02/17	2D 3D TSV
US9290467	51	49	HGNC:2537	Cyclic amides	Hoffmann-La Roche Inc	01/30/17	2D 3D TSV
US9273046	116	58	HGNC:9829 HGNC:1097	Fused tricyclic compounds as Raf kinase inhibitors	BeiGene, Ltd	01/30/17	2D 3D TSV
US9290477	7	7		Inhibitors of β-secretase	Vitae Pharmaceuticals Inc	01/30/17	2D 3D TSV
US9290456	68	66	HGNC:2671	Pyridazinone compounds and their use as DAAO inhibitors	Takeda Pharmaceutical Co., Ltd	01/30/17	2D 3D TSV
US9290451	758	382	HGNC:2160 HGNC:2159	Pyridine derivatives as agonists of the CB2 receptor	Hoffmann-La Roche Inc	01/30/17	2D 3D TSV
US9290463	5	5	HGNC:5295	Radiolabeled compounds and uses thereof	Columbia University	01/30/17	2D 3D TSV
US9290454	27	26	HGNC:4502	Substituted isoquinolines as CRTH2 receptor modulators	Merck Sharp & Dohme Corp	01/30/17	2D 3D TSV
US9273053	82	79	HGNC:933	Sulfur-containing heterocyclic derivative having Beta secretase inhibitory activity	Shionogi & Co., Ltd	01/30/17	2D 3D TSV
US9273043	82	34	HGNC:12716	TRPV1 antagonists including dihydroxy substituent and uses thereof	Purdue Pharma LP	01/30/17	2D 3D TSV
US9249124	141	83	HGNC:11393	Aurora kinase inhibitors and methods of making and using thereof	H. Lee Moffitt Cancer Center and Research Institute Inc	01/27/17	2D 3D TSV
US9273042	9	9	HGNC:933	5-amino[1,4]thiazines as BACE 1 inhibitors	Hoffmann-La Roche Inc	01/25/17	2D 3D TSV
US9273014	82	39	HGNC:7881 HGNC:7883 HGNC:5724	Bis(fluoroalkyl)-1,4-benzodiazepinone compounds and prodrugs thereof	Bristol-Myers Squibb Co.	01/24/17	2D 3D TSV
US9266877	359	187	HGNC:992	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	01/23/17	2D 3D TSV
US9271969	134	67	HGNC:2843	Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme	KAINOS MEDICINE, INC.	01/23/17	2D 3D TSV
US9273021	6	3	HGNC:3606	Dibenzofuran derivatives as inhibitors of fructose 1,6-bisphosphatase and methods of use thereof	Boston College	01/23/17	2D 3D TSV
US9273052	5	5	HGNC:270	Phthalazinone ketone derivative, preparation method thereof, and pharmaceutical use thereof	Jiangsu Hansoh Pharmaceutical Co., Ltd.	01/23/17	2D 3D TSV
US9273029	119	58	HGNC:11584 HGNC:14552	Pyridine-and pyrazine derivatives	Merck Patent GmbH	01/23/17	2D 3D TSV
US9266890	24	19	HGNC:9077 HGNC:6880 HGNC:12401	Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders	Dana-Farber Cancer Institute Inc	01/23/17	2D 3D TSV
US9271981	7	2		Pyrrolo[2,3-D]pyrimidine compounds	Zoetis Services LLC	01/23/17	2D 3D TSV
US9266883	144	143		Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors	Novartis AG	01/23/17	2D 3D TSV
US9266891	61	61	HGNC:29607	Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors	Boehringer Ingelheim International GmbH	01/23/17	2D 3D TSV
US9273011	14	14	HGNC:3357	Substituted pyridazines for the treatment of pain	Inhibitaxin Limited	01/23/17	2D 3D TSV
US9273033	142	135	HGNC:8772	Substituted pyridone derivatives as PDE10 inhibitors	Merck Sharp & Dohme Corp	01/23/17	2D 3D TSV
US9243038	35	29	HGNC:5381	Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof	President and Fellows of Harvard College	01/18/17	2D 3D TSV
US9233167	124	36	HGNC:8153 HGNC:8154 HGNC:8156	Oligomer-opioid agonist conjugates	Nektar Therapeutics	01/18/17	2D 3D TSV
US9233947	11	11		Sulfamides as TRPM8 modulators	Janssen Pharmaceutica NV	01/18/17	2D 3D TSV
US9266876	244	243	HGNC:4383	4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives	Actelion Pharmaceuticals Ltd	01/17/17	2D 3D TSV
US9266870	96	45	HGNC:4849 HGNC:4848	Heteroaromatic methyl cyclic amine derivative	Taisho Pharmaceutical Co., Ltd	01/17/17	2D 3D TSV
US9266878	656	163	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Phosphatidylinositol 3-kinase inhibitors	Gilead Calistoga LLC	01/17/17	2D 3D TSV
US9266880	8	8	HGNC:2593	Substituted azaindazole compounds	Bristol-Myers Squibb Co.	01/17/17	2D 3D TSV
US9266869	118	42	HGNC:6307 HGNC:8804	Substituted dialkyl(oxido)-lambda4-sulfanylidene nicotinamide derivatives as kinase inhibitors	Allergan Inc	01/17/17	2D 3D TSV
US9266895	33	33	HGNC:1133	Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors	Principia Biopharma Inc	01/17/17	2D 3D TSV
US9266881	22	22	HGNC:8772	Triazolopyridinone PDE10 inhibitors	Merck Sharp & Dohme Corp	01/17/17	2D 3D TSV
US9266835	362	171	HGNC:2160 HGNC:2159	Quinoline derivatives useful as CB-1 inverse agonists	Janssen Pharmaceutica NV	01/16/17	2D 3D TSV
US9265773	422	195		Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	01/16/17	2D 3D TSV
US9233921	34	34		Potent poxvirus inhibitor	University of Pennsylvania	01/14/17	2D 3D TSV
US9266848	37	12	HGNC:195 HGNC:7173 HGNC:216 HGNC:7176 HGNC:7155 HGNC:188	4-alkoxy-N-(2-hydroxycarbamoyl-2-piperidinyl-ethyl)-benzamide compounds as selective TACE-inhibitors for the treatment of inflammatory diseases	Galderma Research & Development	01/09/17	2D 3D TSV
US9260455	15	8	HGNC:934	Alkyl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	01/09/17	2D 3D TSV
US9265734	416	206	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors	BioMarin Pharmaceutical Inc	01/09/17	2D 3D TSV
US9266832	90	89	HGNC:11138	Compounds for the treatment of neurodegenerative diseases	Katholieke Universiteit Levun	01/09/17	2D 3D TSV
US9260439	575	509	HGNC:8979 HGNC:8975	Dihydropyrrolopyrimidine derivatives	Pfizer Inc	01/09/17	2D 3D TSV
US9260440	123	68	HGNC:270 HGNC:272 HGNC:15677	Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors	BeiGene, Ltd	01/09/17	2D 3D TSV
US9266828	5	5	HGNC:8568	Inhibitors of Furin and other pro-protein convertases	Sanford-Burnham Medical Research Institute	01/09/17	2D 3D TSV
US9266853	8	2	HGNC:2637 HGNC:2623	Orally available viridiofungin derivative possessing anti-HCV activity	Chugai Seiyaku Kabushiki Kaisha	01/09/17	2D 3D TSV
US9260450	18	9		Therapeutic pyrazolyl thienopyridines	THESAN PHARMACEUTICALS, INC.	01/09/17	2D 3D TSV
US9266839	2	2	HGNC:2625	Trifluoromethyl pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof	Lycera Corporation	01/09/17	2D 3D TSV
US9233965	111	110	HGNC:2453 HGNC:2452	3,4-dihydropyrrolo[1,2-A]pyrazine-2,8(1H)-dicarboxamide derivatives, preparation thereof and therapeutic use thereof for diseases involving casein kinase 1 epsilon and/or casein kinase 1 delta	Sanofi	01/07/17	2D 3D TSV
US9249163	241	117	HGNC:8772	PDE10a inhibitors for the treatment of type II diabetes	Janssen Pharmaceutica NV	12/31/16	2D 3D TSV
US9492405	97	35	HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The United States of America, as represented by the Secretary, Department of Health and Human Services	12/31/16	2D 3D TSV
US9260415	17	17	HGNC:1133	Heteroaryl pyridone and aza-pyridone compounds with electrophilic functionality	Genentech Inc	12/28/16	2D 3D TSV
US9260413	5	5	HGNC:2228	Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders	Merck Sharp & Dohme Corp	12/28/16	2D 3D TSV
US9259422	35	11	HGNC:8154 HGNC:8155	Orvinol and thevinol derivatives useful in the treatment of depression	The University of Bath	12/28/16	2D 3D TSV
US9260410	8	3	HGNC:11283 HGNC:6874 HGNC:6876	P38 MAP kinase inhibitors	Respivert Ltd	12/28/16	2D 3D TSV
US9260425	412	405		Pyrazolo[3,4-c]pyridine compounds and methods of use	Genetech, Inc	12/28/16	2D 3D TSV
US9259470	42	42	HGNC:6871	Serine/threonine kinase inhibitors	Array BioPharma Inc	12/28/16	2D 3D TSV
US9260446	5	5	HGNC:10597	Synthetic methods for spiro-oxindole compounds	Xenon Pharmaceuticals Inc	12/28/16	2D 3D TSV
US9260448	11	11	HGNC:4593	Thienopyrimidinone derivatives as mGluR1 antagonists	Korea Institute of Science and Technology	12/28/16	2D 3D TSV
US9253997	33	33		Alkylamine derivative	Ajinomoto Co. Inc	12/20/16	2D 3D TSV
US9255091	15	5	HGNC:108 HGNC:983	Benzothiazole-based pyridinium compounds	The University of Montana	12/20/16	2D 3D TSV
US9255107	8	8		Heteroaryl alkyne compound and use thereof	NANJING SANHOME PHARMACEUTICAL CO., LTD.	12/20/16	2D 3D TSV
US9255090	449	432	HGNC:4502	Heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators	Actelion Pharmaceuticals Ltd	12/20/16	2D 3D TSV
US9255110	229	176	HGNC:11491 HGNC:6112 HGNC:17967	Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators	Roche Palo Alto LLC	12/20/16	2D 3D TSV
US9255096	26	8	HGNC:6307 HGNC:8804	Substituted 1,2,3,4-tetrahydrobenzo[C][2,7] naphthyridines and derivatives thereof as kinase inhibitors	Allergan Inc	12/20/16	2D 3D TSV
US9255106	46	25	HGNC:270 HGNC:11941 HGNC:272 HGNC:15677	Substituted [1,2,4]triazolo[4,3-a]pyrazines as PARP-1 inhibitors	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/20/16	2D 3D TSV
US9255103	59	52	HGNC:4597	Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators	Vanderbilt University	12/20/16	2D 3D TSV
US9255098	6	4	HGNC:3009	Xanthine derivative	Chengdu Easton Pharmaceutical Co., Ltd.	12/20/16	2D 3D TSV
US9260417	14	1	HGNC:8803 HGNC:6307 HGNC:8590 HGNC:8804 HGNC:1782 HGNC:1097 HGNC:76 HGNC:6342 HGNC:3689 HGNC:9967 HGNC:6876 HGNC:3765	Therapeutic methods and compositions involving allosteric kinase inhibition	AMITECH THERAPEUTIC SOLUTIONS, INC.	12/15/16	2D 3D TSV
US9249085	61	52	HGNC:9594 HGNC:9596	Aniline derivatives, their preparation and their therapeutic application	FOVEA PHARMACEUTICALS	12/12/16	2D 3D TSV
US9249151	126	60		Bis-amido pyridines	Boehringer Ingelheim International GmbH	12/12/16	2D 3D TSV
US9248140	66	32		Chemical compounds	AstraZeneca AB	12/12/16	2D 3D TSV
US9249139	9	9	HGNC:8779	Indolizinone based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof	Council of Scientific & Industrial Research	12/12/16	2D 3D TSV
US9249125	371	93	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Pyrazole derivatives as p38 MAP inhibitors	Respivert Limited	12/12/16	2D 3D TSV
US9249123	8	7	HGNC:1133	Pyridinones/pyrazinones, method of making, and method of use thereof	Genentech Inc	12/12/16	2D 3D TSV
US9249096	30	30	HGNC:6623	Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors	Bristol-Myers Squibb Co.	12/12/16	2D 3D TSV
US9243020	20	12	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	12/12/16	2D 3D TSV
US9255087	12	4	HGNC:5465 HGNC:11393 HGNC:427	Substituted indazole derivatives active as kinase inhibitors	Nerviano Medical Sciences srl	12/12/16	2D 3D TSV
US9249114	74	47	HGNC:11584 HGNC:14552	Thiazole derivatives	Merck Patent GmbH	12/12/16	2D 3D TSV
US9227979	64	30	HGNC:268 HGNC:262 HGNC:263	Fluorescent antagonists of the A3 adenosine receptor	The United States of America, as represented by the Secretary, Department of Health and Human Services	12/08/16	2D 3D TSV
US9260454	41	40	HGNC:11778	Isothiazolopyridine-2-carboxamides and their use as pharmaceuticals	Sanofi	12/08/16	2D 3D TSV
US9242977	42	24		Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	12/06/16	2D 3D TSV
US9242988	7	7		2′-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	12/05/16	2D 3D TSV
US9242996	573	459	HGNC:6871	Aminoheteroaryl benzamides as kinase inhibitors	Novartis AG	12/05/16	2D 3D TSV
US9242973	532	211	HGNC:6251 HGNC:933	Chromane compounds	CoMentis Inc	12/05/16	2D 3D TSV
US9242998	118	59		Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C	Merck Sharp & Dohme Corp	12/05/16	2D 3D TSV
US9243002	192	84		Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C	Merck Sharp & Dohme Corp	12/05/16	2D 3D TSV
US9221809	356	349	HGNC:17967	Aminopyrimidinones as interleukin receptor-associated kinase inhibitors	Merck Sharp & Dohme Corp	11/29/16	2D 3D TSV
US9242943	66	36	HGNC:934 HGNC:2529 HGNC:933 HGNC:2637 HGNC:2625 HGNC:2623	1,4 oxazines as BACE1 and/or BACE2 inhibitors	Siena Biotech SpA	11/28/16	2D 3D TSV
US9242969	416	202	HGNC:1097	Biaryl amide compounds as kinase inhibitors	Novartis AG	11/28/16	2D 3D TSV
US9238625	33	11	HGNC:11050 HGNC:11048 HGNC:11049	Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives	Reviva Pharmaceuticals Inc	11/28/16	2D 3D TSV
US9242981	44	24		Fused pyrazole derivatives as novel ERK inhibitors	Merck Sharp & Dohme Corp	11/28/16	2D 3D TSV
US9242975	27	26	HGNC:17967	Heterocyclic-substituted pyridyl compounds useful as kinase inhibitors	Bristol-Myers Squibb Co.	11/28/16	2D 3D TSV
US9242995	3	3	HGNC:4849	Isoxazolopyridine orexin receptor antagonists	Merck Sharp & Dohme Corp	11/28/16	2D 3D TSV
US9242970	930	464	HGNC:4849 HGNC:4848	Lactam derivatives useful as orexin receptor antagonists	Actelion Pharmaceuticals Ltd	11/28/16	2D 3D TSV
US9242960	4	2	HGNC:6874 HGNC:6876	P38MAP kinase inhibitors	Respivert Ltd	11/28/16	2D 3D TSV
US9242982	7	7	HGNC:8779	Pyridopyrimidine based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof	Council of Scientific & Industrial Research	11/28/16	2D 3D TSV
US9242957	72	24		Thiophene-2-carboximidamide based selective neuronal nitric oxide inhibitors	Northwestern University	11/28/16	2D 3D TSV
US9238651	72	36	HGNC:8816	1-H-pyrrolo[2,3-b]pyridine derivatives	Merck Patent GmbH	11/21/16	2D 3D TSV
US9238626	42	11	HGNC:108 HGNC:933 HGNC:983	Beta-amyloid-directed multitarget compounds for the treatment of alzheimer's disease	Universitat de Barcelona	11/21/16	2D 3D TSV
US9233979	458	446	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp	11/21/16	2D 3D TSV
US9238629	88	22	HGNC:3236	Heteroaryl compounds and uses thereof	Celgene Avilomics Research, Inc.	11/21/16	2D 3D TSV
US9241942	494	278	HGNC:3449	IRE-1α inhibitors	MannKind Corporation	11/21/16	2D 3D TSV
US9238619	76	76	HGNC:11056	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	11/21/16	2D 3D TSV
US9233983	152	147	HGNC:1133	Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof	Advinus Therapeutics Ltd	11/21/16	2D 3D TSV
US9233981	33	32	HGNC:933	Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	11/21/16	2D 3D TSV
US9238658	49	44		Substituted piperidinyl-carboxamide derivatives useful as SCD 1 inhibitors	Janssen Pharmaceutica NV	11/21/16	2D 3D TSV
US9238644	143	81	HGNC:6307 HGNC:3767	VEGFR3 inhibitors	CANCER THERAPEUTICS CRC PTY LIMITED	11/21/16	2D 3D TSV
US9187424	434	289	HGNC:7045	Aryl dihydropyridinones and piperidinone MGAT2 inhibitors	Bristol-Myers Squibb Co.	11/15/16	2D 3D TSV
US9227969	101	99	HGNC:6871	Compounds and compositions as inhibitors of MEK	Novartis AG	11/14/16	2D 3D TSV
US9233108	30	15	HGNC:286 HGNC:1952	Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities	Almirall, S.A.	11/14/16	2D 3D TSV
US9233953	161	160	HGNC:11056	Derivatives of 4-(piperazinylcarbonyl)thiane-1, 1-dione which inhibit GlyT1	Boehringer Ingelheim International GmbH	11/14/16	2D 3D TSV
US9226927	15	15	HGNC:620	Gamma secretase inhibitors	Merck Sharp & Dohme Corp	11/14/16	2D 3D TSV
US9233086	100	100		Inhibition of WDR5 interaction with its binding partners	The Regents of the University of Michigan	11/14/16	2D 3D TSV
US9233968	97	30	HGNC:6307 HGNC:8804	Kinase inhibitors	Allergan Inc	11/14/16	2D 3D TSV
US9227975	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2B]pyridazine compounds	Array BioPharma Inc	11/14/16	2D 3D TSV
US9227977	14	4	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Phosphoinositide 3-kinase inhibitors	Respivert Ltd	11/14/16	2D 3D TSV
US9227973	16	11	HGNC:16709	Pyridine CGRP receptor antagonists	Merck Sharp & Dohme Corp	11/14/16	2D 3D TSV
US9233111	72	67	HGNC:1133	Pyrrolo pyrimidine derivatives	Novartis AG	11/14/16	2D 3D TSV
US9227956	98	41	HGNC:20001	Substituted amide compounds	Pfizer Inc	11/14/16	2D 3D TSV
US9233946	59	57	HGNC:8874 HGNC:8875	Sulfonamide compounds	Kancera AB	11/14/16	2D 3D TSV
US9227970	43	42	HGNC:8772	Triazolopyridine compounds	Hoffmann-La Roche Inc	11/14/16	2D 3D TSV
US9227982	56	26	HGNC:270	4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrminidinyl compounds for use as tankyrase inhibitors	Novartis AG	11/08/16	2D 3D TSV
US9227930	16	15		Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Inc	11/08/16	2D 3D TSV
US9234000	417	198	HGNC:3530 HGNC:6371 HGNC:9475 HGNC:3528 HGNC:3535 HGNC:6357 HGNC:9071	Benzylamine derivatives as inhibitors of plasma kallikrein	Kalvista Pharmaceuticals Limited	11/08/16	2D 3D TSV
US9221831	451	97	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Buprenorphine analogs	Purdue Pharma LP	11/08/16	2D 3D TSV
US9226922	476	458	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp	11/08/16	2D 3D TSV
US9227959	8	6		Ethynyl derivatives	Hoffman-La Roche Inc	11/08/16	2D 3D TSV
US9227949	188	94	HGNC:9490 HGNC:9475	Heteroarylcarboxylic acid ester derivative	Ajinomoto Co. Inc	11/08/16	2D 3D TSV
US9221808	178	88	HGNC:10251 HGNC:10252	Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinase (ROCK) and methods of use	H. Lee Moffitt Cancer Center and Research Institute Inc	11/08/16	2D 3D TSV
US9226923	19	6	HGNC:427 HGNC:7029	Spirocyclic molecules as protein kinase inhibitors	Nanjing Allgen Pharma Co. Ltd.	11/08/16	2D 3D TSV
US9216998	56	27	HGNC:6623	Tricyclic indole derivatives useful endothelial lipase inhibitors	Janssen Pharmaceutica NV	11/08/16	2D 3D TSV
US9217012	22	4	HGNC:16077 HGNC:9670 HGNC:1718 HGNC:9650 HGNC:9661 HGNC:3069 HGNC:9308 HGNC:9642 HGNC:9652 HGNC:9644 HGNC:9646 HGNC:9659 HGNC:122	Inhibitors of protein tyrosine phosphatases	Indiana University Research and Technology Corporation	11/02/16	2D 3D TSV
US9221802	10	10		Arylethynyl derivatives	Hoffman-La Roche Inc	10/31/16	2D 3D TSV
US9221839	30	15	HGNC:934 HGNC:933	C5-C6 oxacyclic-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	10/31/16	2D 3D TSV
US9221832	152	120	HGNC:8537	Heterocyclic amide derivatives as P2X7 receptor antagonists	Actelion Pharmaceuticals Ltd	10/31/16	2D 3D TSV
US9221824	5	5	HGNC:7029	Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors	Incyte Holdings Corporation	10/31/16	2D 3D TSV
US9221797	93	85		Inhibitors of c-fms kinase	Janssen Pharmaceutica NV	10/31/16	2D 3D TSV
US9221791	18	6	HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals Inc	10/31/16	2D 3D TSV
US9221828	21	21	HGNC:10810	N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]sulfonamides as pharmaceuticals	Sanofi	10/31/16	2D 3D TSV
US9221796	174	137		Selective NR2B antagonists	Bristol-Myers Squibb Co.	10/31/16	2D 3D TSV
US9216999	1840	459	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Substituted pyrrolo[2,3-h][1,6]naphthyridines and compositions thereof as JAK inhibitors	Nissan Chemical Industries, Ltd	10/31/16	2D 3D TSV
US9216984	12	2		3-[4-(7H-pyrrolo[2,3-D]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane—or heptane-nitrile as JAK inhibitors	Incyte Corporation	10/24/16	2D 3D TSV
US9216985	41	12	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	3-aryl-2-((arylamino)methyl)quinazolin-4-(3H)-ones	SciFluor Life Sciences, Inc.	10/24/16	2D 3D TSV
US9221790	16	16	HGNC:5299	Benzamide derivatives	Dong-A Pharm. Co., Ltd	10/24/16	2D 3D TSV
US9216988	210	203		Benzyl sulfonamide derivatives as RORc modulators	Genentech Inc	10/24/16	2D 3D TSV
US9216968	239	237	HGNC:9599	Heterocyclic derivative and pharmaceutical drug	Nippon Shinyaku Co. Ltd	10/24/16	2D 3D TSV
US9221795	143	95	HGNC:8977 HGNC:8976	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	10/24/16	2D 3D TSV
US9216981	88	44	HGNC:1097	Purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition with inhibitory activity against Raf kinase, containing same as active ingredient	Medpacto, Inc.	10/24/16	2D 3D TSV
US9216986	52	50		Quinoline derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	10/24/16	2D 3D TSV
US9221767	26	13	HGNC:10251 HGNC:10252	Substituted phthalazinones as rock inhibitors	Bristol-Myers Squibb Co.	10/24/16	2D 3D TSV
US9216962	216	75	HGNC:4852 HGNC:14064 HGNC:4854	Thiazole compounds, methods for preparation and use thereof	Shanghai Puyi Chemical Co., Ltd.	10/24/16	2D 3D TSV
US9216997	21	21	HGNC:3765	Tri-heterocyclic derivatives, preparation process and uses thereof	Shanghai De Novo Pharmatech Co., Ltd	10/24/16	2D 3D TSV
US9216972	69	23	HGNC:3167 HGNC:3165	Tricyclic heterocyclic compounds	Bristol-Myers Squibb Co.	10/24/16	2D 3D TSV
US9090621	104	99	HGNC:1133	Tyrosine kinase inhibitors	Principia Biopharma Inc	10/19/16	2D 3D TSV
US9212206	8	4	HGNC:12823 HGNC:2707	4-Fluoro-Thio-containing inhibitors of APP2, compositions thereof and method of use	TBA	10/18/16	2D 3D TSV
US9216182	192	102	HGNC:5184	Carbamate/urea derivatives containing piperidin and piperazin rings as H3 receptor inhibitors	Novartis AG	10/18/16	2D 3D TSV
US9206164	111	109	HGNC:4502	Pyrazole compounds as CRTH2 antagonists	Boehringer Ingelheim International GmbH	10/18/16	2D 3D TSV
US9212144	43	16	HGNC:7872	2-aminoquinoline-based compounds for potent and selective neuronal nitric oxide synthase inhibition	Northwestern University	10/17/16	2D 3D TSV
US9212184	4	4	HGNC:12401	6-thio-substituted imidazo[1,2-a]pyrazines as Mps-1 inhibitors	Bayer Intellectual Property GmbH	10/17/16	2D 3D TSV
US9212192	59	59	HGNC:427	Bicyclic carboxamide inhibitors of kinases	AbbVie Inc	10/17/16	2D 3D TSV
US9212186	25	19	HGNC:18618	Bicyclic pyrazole LRRK2 small molecule inhibitors	Genentech Inc	10/17/16	2D 3D TSV
US9212147	64	34	HGNC:2671	Dihydroxy aromatic heterocyclic compound	Takeda Pharmaceutical Co., Ltd	10/17/16	2D 3D TSV
US9212171	46	43		Ethynyl compounds	Hoffmann-La Roche Inc	10/17/16	2D 3D TSV
US9212196	105	33		Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof	Universite Paris Descartes	10/17/16	2D 3D TSV
US9212187	13	13	HGNC:6224	Nitrogen-containing compounds and pharmaceutical compositions thereof for the treatment of atrial fibrillation	Otsuka Pharmaceutical Co., Ltd	10/17/16	2D 3D TSV
US9212173	37	36	HGNC:18618	Pyrazole aminopyrimidine derivatives as LRRK2 modulators	Genentech Inc	10/17/16	2D 3D TSV
US9212178	35	32	HGNC:11491	Substituted pyrimidine compounds and their use as SYK inhibitors	Genosco	10/17/16	2D 3D TSV
US9212145	3	3	HGNC:6307	Urea derivatives and uses thereof	Kala Pharmaceuticals, Inc.	10/17/16	2D 3D TSV
US9212140	12	3		(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment	Bayer Intellectual Property GmbH	10/11/16	2D 3D TSV
US9212139	88	67	HGNC:10597	Aryl substituted indoles and their use as blockers of sodium channels	Purdue Pharma LP	10/11/16	2D 3D TSV
US9212165	28	25	HGNC:4597	Bicarbocyclic and tricarbocyclic ethynyl derivatives and uses of same	H. Lundbeck A/S	10/11/16	2D 3D TSV
US9206201	4	1	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β	Counsel of Scientific & Industrial Research	10/11/16	2D 3D TSV
US9212130	181	179	HGNC:8534	Heterocyclic derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	10/11/16	2D 3D TSV
US9206199	217	196	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	10/11/16	2D 3D TSV
US9206232	203	201		Organic compounds and their uses	Novartis AG	10/11/16	2D 3D TSV
US9206188	228	54	HGNC:6190 HGNC:6192 HGNC:1133 HGNC:6193 HGNC:6171	Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors	ARRIEN PHARMACEUTICALS LLC	10/11/16	2D 3D TSV
US9211296	35	35		Therapeutic compounds for blocking DNA synthesis of POX viruses	University of Pennsylvania	10/11/16	2D 3D TSV
US9206173	137	88	HGNC:4464	Heterocyclic compounds for the treatment of stress-related conditions	Otsuka Pharmaceutical Co., Ltd	10/10/16	2D 3D TSV
US9216974	16	15	HGNC:620	Phenoxazine derivatives and methods of use thereof	Washington University	10/04/16	2D 3D TSV
US9206129	53	53		Agent for treatment of eye diseases	Daito Chemix Corporation	10/03/16	2D 3D TSV
US9206139	65	5	HGNC:7160 HGNC:7173 HGNC:7174 HGNC:7175 HGNC:7176 HGNC:7155 HGNC:7166 HGNC:7158 HGNC:7159 HGNC:220 HGNC:221	Aggrecanase inhibitors	Eli Lilly and Company	10/03/16	2D 3D TSV
US9206184	219	115	HGNC:3690 HGNC:3688	Disubstituted benzothienyl-pyrrolotriazines and uses thereof	Bayer Intellectual Property GmbH	10/03/16	2D 3D TSV
US9212153	549	541		Inhibitors of beta-secretase	Vitae Pharmaceuticals Inc	10/03/16	2D 3D TSV
US9206198	113	76	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	10/03/16	2D 3D TSV
US9206167	122	65		Piperazine-substituted benzothiophenes for treatment of mental disorders	Otsuka Pharmaceutical Co., Ltd	10/03/16	2D 3D TSV
US9206162	53	50	HGNC:5258	Triazole compounds that modulate Hsp90 activity	Synta Pharmaceuticals Corp.	10/03/16	2D 3D TSV
US9205085	73	72		Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction	Emory University	10/03/16	2D 3D TSV
US9200020	75	27	HGNC:5157	6-oxopurine phosphoribosyltransferase inhibitors	The University of Queensland	09/27/16	2D 3D TSV
US9199981	176	168	HGNC:6342	Compounds and compositions as C-kit kinase inhibitors	Novartis AG	09/27/16	2D 3D TSV
US9200268	5	5	HGNC:3528	Compounds and methods for purification of serine proteases	Portola Pharmaceuticals Inc	09/27/16	2D 3D TSV
US9199976	17	17	HGNC:17890	Haematopoietic-prostaglandin D2 synthase inhibitors	The University of Queensland	09/27/16	2D 3D TSV
US9205078	4	1	HGNC:76	N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia	Pfizer Inc	09/27/16	2D 3D TSV
US9200006	26	6	HGNC:2536 HGNC:2537 HGNC:2545	Protease inhibitors	Medivir AB	09/27/16	2D 3D TSV
US9199997	3	1	HGNC:4037 HGNC:6735 HGNC:6524	Purinone derivative hydrochloride	Ono Pharmaceutical Co., Ltd	09/27/16	2D 3D TSV
US9200016	173	167	HGNC:8772	Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)	Allergan Inc	09/27/16	2D 3D TSV
US9199999	76	73	HGNC:12401	Substituted imidazopyrazines	Bayer Intellectual Property GmbH	09/27/16	2D 3D TSV
US9200001	119	117		Triazolyl PDE10 inhibitors	Merck Sharp & Dohme Corp	09/27/16	2D 3D TSV
US9199947	140	139		Biaryl-propionic acid derivatives and their use as pharmaceuticals	Sanofi	09/20/16	2D 3D TSV
US9199927	112	55	HGNC:9475	Guanidinobenzoic acid compound	Astellas Pharma Inc	09/20/16	2D 3D TSV
US9199944	157	90	HGNC:427	N2,N4-bis(4-(piperazine-1-yl)phenyl)pirimidine-2,4-diamine derivative or pharmaceutically acceptable salt thereof, and composition containing same as active ingredient for preventing or treating cancer	Korea Research Institute of Chemical Technology	09/20/16	2D 3D TSV
US9199949	11	7	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc	09/20/16	2D 3D TSV
US9193689	18	18		3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use	Institute of Cancer Research	09/19/16	2D 3D TSV
US9187487	46	46		Azaindole derivatives as tyrosine kinase inhibitors	Principia Biopharma Inc	09/19/16	2D 3D TSV
US9192603	67	66	HGNC:4596	Heterocyclic sulfone mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	09/19/16	2D 3D TSV
US9193697	39	38	HGNC:3553	Oxazole derivatives useful as modulators of FAAH	Merck Sharp & Dohme Corp	09/19/16	2D 3D TSV
US9193736	311	166		PDE 10a inhibitors for the treatment of type II diabetes	Janssen Pharmaceutica NV	09/19/16	2D 3D TSV
US9193762	57	32	HGNC:9344	Selective inhibitors of prolylcarboxypeptidase	University of Mississippi	09/19/16	2D 3D TSV
US9193726	73	72	HGNC:9508	Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders	Pfizer Inc	09/19/16	2D 3D TSV
US9187470	12	9	HGNC:6875	Anti-mucus drugs and uses therefor	Washington University	09/12/16	2D 3D TSV
US9187477	16	15	HGNC:9376	Azabenzimidazole derivatives	Boehringer Ingelheim International GmbH	09/12/16	2D 3D TSV
US9187486	205	101	HGNC:8987	Bicyclic pyridazine compounds as Pim inhibitors	Amgen Inc	09/12/16	2D 3D TSV
US9187466	60	30	HGNC:897 HGNC:895	Bisaryl-bonded aryltriazolones and use thereof	Bayer Intellectual Property GmbH	09/12/16	2D 3D TSV
US9187469	20	17	HGNC:9413	Morpholinylbenzotriazines for use in cancer therapy	Merck Patent GmbH	09/12/16	2D 3D TSV
US9187480	48	22	HGNC:2160 HGNC:2159	Peripherally restricted diphenyl purine derivatives	Research Triangle Institute	09/12/16	2D 3D TSV
US9187459	10	5	HGNC:3430 HGNC:3236	Quinazoline-7-ether compounds and methods of use	NewGen Therapeutics, Inc.	09/12/16	2D 3D TSV
US9187474	8	2	HGNC:9829 HGNC:1097 HGNC:646	Raf inhibitor compounds	Deciphera Pharmaceuticals LLC	09/12/16	2D 3D TSV
US9187437	45	24	HGNC:3167 HGNC:3165	Substituted oxadiazole compounds	Bristol-Myers Squibb Co.	09/12/16	2D 3D TSV
US9187450	56	56	HGNC:1869	Substituted pyridine compound	Daiichi Sankyo Company, Limited	09/12/16	2D 3D TSV
US9187462	122	118		Substituted quinazolines as serine/threonine kinase inhibitors	Array BioPharma Inc	09/12/16	2D 3D TSV
US9187441	88	84	HGNC:6973	p53-Mdm2 antagonists	University of Pittsburgh	09/12/16	2D 3D TSV
US9187406	25	9	HGNC:7175 HGNC:7176 HGNC:7166 HGNC:7159	Curcumin analogues as zinc chelators and their uses	The Research Foundation of State University of New York	09/06/16	2D 3D TSV
US9182402	47	16	HGNC:5155	Hepsin inhibitors	Fred Hutchinson Cancer Research Center	09/06/16	2D 3D TSV
US9181263	149	25	HGNC:6193 HGNC:6171 HGNC:11491 HGNC:11283 HGNC:12841 HGNC:9617 HGNC:3432 HGNC:4840 HGNC:6735 HGNC:3697 HGNC:4037 HGNC:3430 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:76 HGNC:11719 HGNC:3236 HGNC:2444 HGNC:6524 HGNC:3655	Inhibitors of bruton's tyrosine kinase	Pharmacyclics LLC	09/06/16	2D 3D TSV
US9187413	6	6		Peripherally restricted FAAH inhibitors	University of California	09/06/16	2D 3D TSV
US9187429	211	72	HGNC:2592 HGNC:2591	Phenyl-tetrahydroisoquinoline derivatives	Hoffmann-La Roche Inc	09/06/16	2D 3D TSV
US9187430	9	9	HGNC:270	Poly (ADP-ribose) polymerase inhibitor	CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.	09/06/16	2D 3D TSV
US9186318	31	2	HGNC:11283 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:427 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:18128 HGNC:4852 HGNC:6307 HGNC:8804 HGNC:6342 HGNC:4854 HGNC:7029 HGNC:9967 HGNC:4853 HGNC:3765	Quinolyl-containing hydroxamic acid compound and preparation method thereof, and pharmaceutical composition containing this compound and use thereof	Beijing Konruns Pharmaceutical Co., Ltd	09/06/16	2D 3D TSV
US9187428	150	49	HGNC:262 HGNC:263 HGNC:264	Substituted dicyanopyridines and use thereof	Bayer Intellectual Property GmbH	09/06/16	2D 3D TSV
US9187397	23	11	HGNC:7794 HGNC:6204	Therapeutic curcumin derivatives	STC.UNM	09/06/16	2D 3D TSV
US9186360	490	103	HGNC:12716 HGNC:497 HGNC:18084 HGNC:18083 HGNC:17961	Treatment of respiratory disorders using TRPA1 antagonists	GLENMARK PHARMACEUTICALS S.A.	09/06/16	2D 3D TSV
US9181266	321	98	HGNC:270 HGNC:11941 HGNC:272 HGNC:15677	2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors	Novartis AG	08/29/16	2D 3D TSV
US9181236	290	174	HGNC:934 HGNC:933	2-spiro-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions and their use	Merck Sharp & Dohme Corp	08/29/16	2D 3D TSV
US9181253	52	22	HGNC:262 HGNC:263	Adenosine receptor agonists, partial agonists, and antagonists	The United States of America, as represented by the Secretary, Department of Health and Human Services	08/29/16	2D 3D TSV
US9181272	300	265		Aldosterone synthase inhibitors	Boehringer Ingelheim International GmbH	08/29/16	2D 3D TSV
US9181279	16	15	HGNC:9596	Cyclic amine derivatives as EP4 receptor antagonists	ROTTAPHARM BIOTECH S.R.L.	08/29/16	2D 3D TSV
US9181233	28	28	HGNC:25952	Inhibitors of glutaminyl cyclase	Probiodrug AG	08/29/16	2D 3D TSV
US9181275	4	4		Mercaptoamidine derivatives and methods of use	AbbVie Inc	08/29/16	2D 3D TSV
US9181258	130	64	HGNC:8987	Substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-ones as protein kinase inhibitors	Nerviano Medical Sciences srl	08/29/16	2D 3D TSV
US9181249	142	140	HGNC:4515	Substituted pyrido[3,4-b]pyrazines as GPR6 modulators	Takeda Pharmaceutical Co., Ltd	08/29/16	2D 3D TSV
US9181261	10	10	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	08/29/16	2D 3D TSV
US9181181	77	41		2-substituted-3-phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease	Albireo AB	08/15/16	2D 3D TSV
US9180122	35	35	HGNC:2671	5- or 6-substituted 3-hydroxy-2 (1 H)-pyridinones as D-amino acid oxidase (DAAO) inhibitors in therapy of diseases such as schizophrenia, cognitive disorder and pain	Takeda Pharmaceutical Co., Ltd	08/15/16	2D 3D TSV
US9181219	48	20	HGNC:10588 HGNC:6251 HGNC:12716 HGNC:18084	Compounds of modulating TRPV3 function	Hydra Biosciences Inc	08/15/16	2D 3D TSV
US9180116	72	31	HGNC:9594 HGNC:9596	Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions	Cayman Chemical Company Inc	08/15/16	2D 3D TSV
US9175357	23	23	HGNC:9077	Fragment ligated inhibitors selective for the polo box domain of PLK1	University of South Carolina	08/15/16	2D 3D TSV
US9181185	25	22	HGNC:10597	Heteroaryl compounds as sodium channel blockers	Purdue Pharma LP	08/15/16	2D 3D TSV
US9181184	18	17		Method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives	Amicus Therapeutics, Inc	08/15/16	2D 3D TSV
US9181230	110	54		Morpholine compounds and uses thereof	Hoffmann-La Roche Inc	08/15/16	2D 3D TSV
US9180183	18	8	HGNC:2637 HGNC:2615 HGNC:2638 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2631 HGNC:2621	Phospholipid drug analogs	Telormedix SA	08/15/16	2D 3D TSV
US9181182	40	35	HGNC:3167 HGNC:3165 HGNC:433	S1P receptors modulators	Akaal Pharma PTY Ltd	08/15/16	2D 3D TSV
US9180120	38	19	HGNC:897 HGNC:895	Substituted N-phenethyltriazoloneacetamides and use thereof	Bayer Intellectual Property GmbH	08/15/16	2D 3D TSV
US9181187	12	12		Therapeutic agent for urinary excretion disorder	Ono Pharmaceutical Co., Ltd	08/15/16	2D 3D TSV
US9180192	46	46	HGNC:4596	mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	08/15/16	2D 3D TSV
US9174997	29	29	HGNC:3309	4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereof	Bayer Intellectual Property GmbH	08/08/16	2D 3D TSV
US9174982	360	346	HGNC:990	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	08/08/16	2D 3D TSV
US9175000	27	7	HGNC:8154 HGNC:8156	Buprenorphine analogs	Purdue Pharma LP	08/08/16	2D 3D TSV
US9174969	73	68	HGNC:9644 HGNC:9659	Indoline scaffold SHP-2 inhibitors and cancer treatment method	University of South Florida	08/08/16	2D 3D TSV
US9175331	256	63	HGNC:3527	Inhibitors of human EZH2, and methods of use thereof	Epizyme Inc	08/08/16	2D 3D TSV
US9174974	85	43	HGNC:3544	Macrocyclic factor VIIa inhibitors	Bristol-Myers Squibb Co.	08/08/16	2D 3D TSV
US9174999	20	11		Methods and compositions for studying, imaging, and treating pain	The Board of Trustees of the Leland Stanford Junior University	08/08/16	2D 3D TSV
US9174993	27	27	HGNC:10810	N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals	Sanofi	08/08/16	2D 3D TSV
US9175320	1	1	HGNC:3165	Processes for the preparation of (R)-2-(7-4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[B]indol-3-yl)acetic acid and salts thereof	Arena Pharmaceuticals Inc	08/08/16	2D 3D TSV
US9175003	234	233	HGNC:4324	Substituted azoanthracene derivatives and intermediates for preparation thereof	vTv Therapeutics LLC	08/08/16	2D 3D TSV
US9173884	107	25	HGNC:8791 HGNC:8793 HGNC:8784 HGNC:8795 HGNC:8773 HGNC:8772 HGNC:8775 HGNC:8787 HGNC:8778	Inhibitors of phosphodiesterase 11 (PDE11)	Boston College	08/02/16	2D 3D TSV
US9173935	18	8	HGNC:2637 HGNC:2615 HGNC:2638 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2631 HGNC:2621	Phospholipid drug analogs	Telormedix SA	08/02/16	2D 3D TSV
US9174965	6	6		Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators	Bristol-Myers Squibb Co.	08/02/16	2D 3D TSV
US9174940	29	24	HGNC:12373	TSH receptor antagonizing tetrahydroquinoline compounds	Merck Sharp & Dohme B.V.	08/02/16	2D 3D TSV
US9169270	120	120	HGNC:4502	1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators	Actelion Pharmaceuticals Ltd	08/01/16	2D 3D TSV
US9169260	399	394	HGNC:17967	Amidopyrazole inhibitors of interleukin receptor-associated kinases	Merck Sharp & Dohme Corp	08/01/16	2D 3D TSV
US9173879	6	1	HGNC:11050 HGNC:11048 HGNC:11049	Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof	Bristol-Myers Squibb Co.	08/01/16	2D 3D TSV
US9173869	43	43		Mediators of hedgehog signaling pathways, compositions and uses related thereto	Curis Inc	08/01/16	2D 3D TSV
US9169246	207	205	HGNC:16672	Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof	Sanofi	08/01/16	2D 3D TSV
US9073941	179	134		Compounds and methods for treating tuberculosis infection	Academia Sinica	07/26/16	2D 3D TSV
US9169224	209	155	HGNC:3553	Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase	Janssen Pharmaceutica NV	07/26/16	2D 3D TSV
US9169243	45	45	HGNC:391	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences Inc	07/25/16	2D 3D TSV
US9169209	118	118	HGNC:30092	Compounds and compositions for the inhibition of NAMPT	FORMA TM, LLC	07/25/16	2D 3D TSV
US9169252	645	585	HGNC:17967	Heteroaryl substituted nicotinamide compounds	Bristol-Myers Squibb Co.	07/25/16	2D 3D TSV
US9169259	92	91		Imidazopyridazine compounds	Hoffmann-La Roche Inc	07/25/16	2D 3D TSV
US9169240	92	83	HGNC:6623	Ketone linked benzothiazole inhibitors of endothelial lipase	Bristol-Myers Squibb Co.	07/25/16	2D 3D TSV
US9079895	129	35		Morpholino compounds, uses and methods	University of Dundee	07/25/16	2D 3D TSV
US9169234	24	12	HGNC:11257	Sepiapterin reductase inhibitors for the treatment of pain	Children's Medical Center Corporation	07/25/16	2D 3D TSV
US9163017	17	17		Anti-viral compounds	AbbVie Inc	07/18/16	2D 3D TSV
US9168247	6	6	HGNC:3091	Beta carboline derivatives useful in the treatment of proliferative disorders	FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX	07/18/16	2D 3D TSV
US9163012	94	74	HGNC:5208	Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1	Vitae Pharmaceuticals Inc	07/18/16	2D 3D TSV
US9163011	106	37	HGNC:934 HGNC:933 HGNC:620	Oxazine derivatives and their use in the treatment of disease	Novartis AG	07/18/16	2D 3D TSV
US9163042	24	24		Prodrugs of pyridone amides useful as modulators of sodium channels	Vertex Pharmaceuticals Inc	07/18/16	2D 3D TSV
US9163015	90	90	HGNC:4596	Pyrazolopyridine, pyrarolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	07/18/16	2D 3D TSV
US9169205	200	197	HGNC:85	Pyrrolidine derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	07/18/16	2D 3D TSV
US9163021	236	210	HGNC:8031	Pyrrolo[3,2-c]pyridine tropomyosin-related kinase inhibitors	Pfizer Inc	07/18/16	2D 3D TSV
US9168248	27	26	HGNC:10571	Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase	Merck Canada Inc.	07/18/16	2D 3D TSV
US9163040	1	1	HGNC:7154	Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors	Novartis AG	07/18/16	2D 3D TSV
US9163013	34	31	HGNC:1771 HGNC:8749 HGNC:4617 HGNC:3091	Use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors	AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.	07/18/16	2D 3D TSV
US9162979	50	47	HGNC:9605	1,5-Diary1-2-alkylpyrrole-3-substituted nitro esters, selective COX-2 inhibitors and nitric oxide donors	ROTTAPHARM BIOTECH S.R.L.	07/11/16	2D 3D TSV
US9161945	2	1	HGNC:11037 HGNC:11036	4-isopropyl-6-methoxyphenyl glucitol compound	Taisho Pharmaceutical Co., Ltd	07/11/16	2D 3D TSV
US9163003	106	38	HGNC:270 HGNC:11941 HGNC:272 HGNC:15677	4-piperidinyl compounds for use as tankyrase inhibitors	Novartis AG	07/11/16	2D 3D TSV
US9163007	94	87	HGNC:1745	5-substituted indazoles as kinase inhibitors	AbbVie Inc	07/11/16	2D 3D TSV
US9169182	4	2		Chrysophaentin analogs that inhibit FtsZ protein	The United States of America, as represented by the Secretary, Department of Health and Human Services	07/11/16	2D 3D TSV
US9162991	55	53		Cinnamoyl inhibitors of transglutaminase	University of Ottawa	07/11/16	2D 3D TSV
US9156822	144	44	HGNC:3026 HGNC:3023 HGNC:3024 HGNC:5286 HGNC:3020 HGNC:5295 HGNC:5294	Functionally selective ligands of dopamine D2 receptors	University of North Carolina at Chapel Hill	07/11/16	2D 3D TSV
US9163010	3	2	HGNC:3763 HGNC:6307	Indolinone protein kinase inhibitors	Beta Pharma, Inc.	07/11/16	2D 3D TSV
US9163008	122	103	HGNC:10597	Pyrimidines as sodium channel blockers	Purdue Pharma LP	07/11/16	2D 3D TSV
US9161939	7	2	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrrolo[2,3-d]pyrimidine compounds	Zoetis Services LLC	07/11/16	2D 3D TSV
US9168255	39	30	HGNC:10597	Quinazoline compounds as sodium channel blockers	Purdue Pharma LP	07/11/16	2D 3D TSV
US9162983	5	5	HGNC:108	Reactivators of organophosphorous inhibited acetylcholinesterase	Southwest Research Institute	07/11/16	2D 3D TSV
US9156845	422	204	HGNC:18618	4-(substituted amino)-7H-pyrrolo[2,3-d] pyrimidines as LRRK2 inhibitors	Pfizer Inc	06/30/16	2D 3D TSV
US9161922	34	26		Amine oxidase inhibitors	Case Western Reserve University	06/30/16	2D 3D TSV
US9156856	44	44	HGNC:992	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	06/30/16	2D 3D TSV
US9156831	41	10	HGNC:882 HGNC:8975 HGNC:8977 HGNC:8976	Chemical compounds	AstraZeneca AB	06/30/16	2D 3D TSV
US9156829	308	148	HGNC:4849 HGNC:4848	Cycloalkyl and heterocycloalkyl compounds as orexin receptor antagonists	Takeda Pharmaceutical Co., Ltd	06/30/16	2D 3D TSV
US9161924	6	5	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	06/30/16	2D 3D TSV
US9156830	87	52	HGNC:12716	Heterocyclic compounds	Shionogi & Co., Ltd	06/30/16	2D 3D TSV
US9156852	39	8	HGNC:9829 HGNC:1097 HGNC:2730 HGNC:2731	Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases	Hanmi Pharm. Co., Ltd	06/30/16	2D 3D TSV
US9156848	4	4	HGNC:3009	Treating diabetes with dipeptidyl peptidase-IV inhibitors	Merck Sharp & Dohme Corp	06/30/16	2D 3D TSV
US9156836	5	5	HGNC:5258	Tricyclic triazole compounds that modulate HSP90 activity	Synta Pharmaceuticals Corp.	06/30/16	2D 3D TSV
US9150566	561	198	HGNC:2637 HGNC:4849 HGNC:4848	2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-YL)picolinamide derivatives as orexin receptor antagonists	Actelion Pharmaceuticals Ltd	06/20/16	2D 3D TSV
US9150578	174	171		5,8-dihydro-6H-pyrazolo[3,4-h]quinazolines as IGF-1R/IR inhibitors	Boehringer Ingelheim International GmbH	06/20/16	2D 3D TSV
US9150526	208	208		Biaryl-propionic acid derivatives and their use as pharmaceuticals	Sanofi	06/20/16	2D 3D TSV
US9155743	90	44	HGNC:590 HGNC:592	Bicyclic heterocycle compounds and their uses in therapy	Astex Therapeutics Limited	06/20/16	2D 3D TSV
US9150583	8	8	HGNC:1869	Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation	Boehringer Ingelheim International GmbH	06/20/16	2D 3D TSV
US9150577	239	237	HGNC:10431	Heterocyclic compounds containing an indole core	Boehringer Ingelheim International GmbH	06/20/16	2D 3D TSV
US9156811	829	505	HGNC:7857	N-myristoyl transferase inhibitors	Univeristy of Dundee	06/20/16	2D 3D TSV
US9150581	30	11		Nicotinic receptor compounds	Research Triangle Institute	06/20/16	2D 3D TSV
US9150579	6	6	HGNC:8977	Selective PI3K delta inhibitors	Rhizen Pharmaceuticals SA	06/20/16	2D 3D TSV
US9156810	66	22	HGNC:9594 HGNC:9593 HGNC:9596 HGNC:9595	Treatment of inflammatory bowel disease	Allergan Inc	06/20/16	2D 3D TSV
US9150519	242	154	HGNC:3167 HGNC:3165	6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis	Merck Serono	06/14/16	2D 3D TSV
US9145414	77	68	HGNC:6307 HGNC:11491 HGNC:11390	1,2,4-triazine-6-carboxamide derivative	Taiho Pharmaceutical Co., Ltd	06/13/16	2D 3D TSV
US9149477	5	5	HGNC:8977	5-fluoro-3-phenyl-2-[1-(9h-purin-6-ylamino)propyl]-3h-quinazolin-4-one as an inhibitor of human phosphatidylinositol 3-kinase delta	ICOS Corporation	06/13/16	2D 3D TSV
US9145402	38	37	HGNC:18618	Aminopyrimidine derivatives as LRRK2 modulators	Genentech Inc	06/13/16	2D 3D TSV
US9145391	266	242	HGNC:11491	Bipyridylaminopyridines as Syk inhibitors	Merck Sharp & Dohme Corp	06/13/16	2D 3D TSV
US9145380	240	239	HGNC:17822	Bis-(sulfonylamino) derivatives for use in therapy	AstraZeneca AB	06/13/16	2D 3D TSV
US9144538	75	68	HGNC:2637	Cosmetic compositions containing substituted azole and methods for alleviating the signs of photoaged skin	The Procter & Gamble Company	06/13/16	2D 3D TSV
US9145392	772	399	HGNC:391 HGNC:10436	Imidazole amines as modulators of kinase activity	Merck Patent GmbH	06/13/16	2D 3D TSV
US9145419	10	10	HGNC:2593	Imidazopyridazinyl compounds	Bristol-Myers Squibb Co.	06/13/16	2D 3D TSV
US9150527	8	2	HGNC:2593 HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Innocrin Pharmaceuticals, Inc.	06/13/16	2D 3D TSV
US9149492	26	13	HGNC:11177 HGNC:11178	Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease	Dartmouth College	06/13/16	2D 3D TSV
US9145354	231	217		Pharmaceutical compounds	Astex Therapeutics Limited	06/13/16	2D 3D TSV
US9145426	38	19	HGNC:934 HGNC:933	Pyrrolidine-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	06/13/16	2D 3D TSV
US9145412	77	26	HGNC:4852 HGNC:4854 HGNC:4853	Selective HDAC1 and HDAC2 inhibitors	Acetylon Pharmaceuticals Inc	06/13/16	2D 3D TSV
US9145418	10	5	HGNC:8987	Substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-ones as protein kinase inhibitors	Nerviano Medical Sciences srl	06/13/16	2D 3D TSV
US9145408	44	7	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Substituted-quinoxaline-type bridged-piperidine compounds as ORL-1 modulators	Purdue Pharma LP	06/13/16	2D 3D TSV
US9150544	176	91	HGNC:3551 HGNC:3528	Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application	Sanofi	06/13/16	2D 3D TSV
US9150546	325	325	HGNC:8534	Triazine derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	06/13/16	2D 3D TSV
US9139578	26	24	HGNC:6623	Amide or urea containing benzothiazole inhibitors of endothelial lipase	Bristol-Myers Squibb Co.	06/06/16	2D 3D TSV
US9139593	21	21	HGNC:3402	Azetidine compounds, compositions and methods of use	Hoffmann-La Roche Inc	06/06/16	2D 3D TSV
US9138393	75	68	HGNC:2637	Cosmetic compositions containing substituted azole and methods for improving the appearance of aging skin	The Procter & Gamble Company	06/06/16	2D 3D TSV
US9139568	167	119	HGNC:391 HGNC:10436	Heterocyclic carboxamides as modulators of kinase activity	Merck Patent GmbH	06/06/16	2D 3D TSV
US9139585	51	49	HGNC:6255	Inhibitors of the Renal Outer Medullary Potassium channel	Merck Sharp & Dohme Corp	06/06/16	2D 3D TSV
US9138431	13	7	HGNC:17383 HGNC:5182	Methods of treatment of histamine H-4 receptor-related pruritus	BRIDGE PHARMA, INC.	06/06/16	2D 3D TSV
US9138494	8	8	HGNC:8772	Radiolabeled PDE10A ligands	AbbVie Inc	06/06/16	2D 3D TSV
US9139529	80	80		Substituted quinoxalines as sodium channel modulators	Vertex Pharmaceuticals Inc	06/06/16	2D 3D TSV
US9139577	328	295	HGNC:7110 HGNC:7111	Sulfoximine substituted quinazolines for pharmaceutical compositions	Boehringer Ingelheim International GmbH	06/06/16	2D 3D TSV
US9139546	32	16	HGNC:2160 HGNC:2159	Tri-aryl/heteroaromatic cannabinoids and use thereof	The University of Tennessee Research Foundation	06/06/16	2D 3D TSV
US9138423	2	2	HGNC:4982	Use of inhibitors of porphobilinogen deaminase in the treatment of congenital erythropoietic porphyria	Asociación Centro de Investigación Cooperativa en Biociencias—CIC Biogune	06/06/16	2D 3D TSV
US9133180	33	11	HGNC:11393 HGNC:11390 HGNC:3765	Aurora and FLT3 kinases modulators	SAREUM LIMITED	05/23/16	2D 3D TSV
US8772323	260	259	HGNC:19060	Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonists	Boehringer Ingelheim International GmbH	05/23/16	2D 3D TSV
US9133171	193	39	HGNC:1780 HGNC:1373 HGNC:1771 HGNC:1368	Disubstituted 5-fluoro pyrimidine derivatives containing a sulfoximine group	Bayer Intellectual Property GmbH	05/23/16	2D 3D TSV
US8829029	164	82	HGNC:3024	Dual modulators of 5HT2A and D3 receptors	Hoffmann-La Roche Inc	05/23/16	2D 3D TSV
US9133183	27	9	HGNC:6307 HGNC:7029	Imidazolidinones and analogs exhibiting anti-cancer and anti-proliferative activities	Deciphera Pharmaceuticals LLC	05/23/16	2D 3D TSV
US9133201	12	10	HGNC:1133	Inhibitors of Bruton's tyrosine kinase	Pharmacyclics Inc	05/23/16	2D 3D TSV
US9133197	12	7	HGNC:262 HGNC:263	Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments	Sigma-Tau Industrie Farmaceutiche Riunite SpA	05/23/16	2D 3D TSV
US8865745	19	19	HGNC:8781	Pyrazolone derivatives as PDE4 inhibitors	Takeda GmbH	05/23/16	2D 3D TSV
US9133199	2	2	HGNC:9077	Pyrimidine derivatives as protein kinase inhibitors	Cyclacel Limited	05/23/16	2D 3D TSV
US9133182	37	37		Selective androgen receptor modulators	Radius Health, Inc.	05/23/16	2D 3D TSV
US9133187	85	85	HGNC:6871	Serine/threonine kinase inhibitors	Array BioPharma Inc	05/23/16	2D 3D TSV
US9132129	8	6	HGNC:9527	Antiviral compounds	Katholieke Universiteit Leuven	05/16/16	2D 3D TSV
US9133148	91	91		Carbamate compounds and of making and using same	The Scripps Research Institute	05/16/16	2D 3D TSV
US9133157	134	130		HIV protease inhibitors	Merck Canada Inc.	05/16/16	2D 3D TSV
US9133134	1	1	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Pharmacyclics LLC	05/16/16	2D 3D TSV
US9132134	10	4	HGNC:3023 HGNC:3024 HGNC:5182	Methods for treating GI tract disorders	Neurogastrx, Inc.	05/16/16	2D 3D TSV
US9133125	72	38	HGNC:8156	Morphan and morphinan analogues, and methods of use	ALKERMES PHARMA IRELAND LIMITED	05/16/16	2D 3D TSV
US9133168	168	117	HGNC:391	Pyrimidine derivatives, preparation thereof, and pharmaceutical use thereof as akt(pkb) phosphorylation inhibitors	Sanofi	05/16/16	2D 3D TSV
US9133131	27	19	HGNC:10597	Pyrimidine diol amides as sodium channel blockers	Purdue Pharma LP	05/16/16	2D 3D TSV
US9133160	15	15	HGNC:2593	Substituted benzimidazole and imidazopyridine compounds useful as CYP17 modulators	Bristol-Meyers Squibb Company	05/16/16	2D 3D TSV
US9133162	13	7	HGNC:6307 HGNC:7029	Substituted quinoline compounds and methods of use	Sunshine Lake Pharma Co., Ltd	05/16/16	2D 3D TSV
US9133105	4	4	HGNC:6997	Transcription factor modulators	C&C BIOPHARMA, LLC	05/16/16	2D 3D TSV
US9126978	10	5	HGNC:10251	1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties	The Regents of the University of Michigan	05/09/16	2D 3D TSV
US9126979	24	12	HGNC:990	Compounds for inhibiting the interaction of BCL2 with binding partners	Novartis AG	05/09/16	2D 3D TSV
US9126980	90	45	HGNC:990	Compounds for inhibiting the interaction of BCL2 with binding partners	Novartis AG	05/09/16	2D 3D TSV
US9127027	37	36	HGNC:3402	Epoxyeicosatrienoic acid analogs and methods of making and using the same	The Medical College of Wisconsin, Inc.	05/09/16	2D 3D TSV
US9126987	25	25	HGNC:9753	Inhibitors of glutaminyl cyclase	Probiodrug AG	05/09/16	2D 3D TSV
US9127005	20	9	HGNC:9067	Isoform selective phospholipase D inhibitors	Vanderbilt University	05/09/16	2D 3D TSV
US9126952	67	67	HGNC:9413	Morpholinylquinazolines	Merck Patent GmbH	05/09/16	2D 3D TSV
US9126973	76	57	HGNC:17890	Multiheteroaryl compounds as inhibitors of H-PGDS and their use for treating prostaglandin D2 mediated diseases	CAYMAN CHEMICAL COMPANY, INCORPORATED	05/09/16	2D 3D TSV
US9126957	10	10	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Merck Sharp & Dohme Corp	05/09/16	2D 3D TSV
US9127001	68	63	HGNC:6278	Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them	Sanofi	05/09/16	2D 3D TSV
US9126976	41	41	HGNC:1869	Substituted benzopiperazines as CETP inhibitors	Merck Sharp & Dohme Corp	05/09/16	2D 3D TSV
US9125915	17	17	HGNC:29607	Antitumor agent	Mitsubishi Tanabe Pharma Corporation	05/02/16	2D 3D TSV
US9125913	853	431	HGNC:990	Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases	AbbVie Inc	05/02/16	2D 3D TSV
US9126948	14	14	HGNC:8977	Pyrimidine-4,6-diamine derivatives as PI3K inhibitors	Incyte Holdings Corporation	05/02/16	2D 3D TSV
US9120812	515	260	HGNC:8979 HGNC:3942	Pyrimidooxazocine derivatives as mTOR-inhibitors	Sanofi	05/02/16	2D 3D TSV
US9120838	4	4	HGNC:11892	Saccharide conjugates	Curators of the University of Missouri	05/02/16	2D 3D TSV
US9120808	141	42		Substituted clavulanic acid	NABRIVA THERAPEUTICS AG	05/02/16	2D 3D TSV
US9126947	6	6	HGNC:427	Substituted pyridazine carboxamide compounds	Xcovery Holding Company LLC	05/02/16	2D 3D TSV
US9126931	266	262	HGNC:427	Tetracyclic compound	Chugai Seiyaku Kabushiki Kaisha	05/02/16	2D 3D TSV
US9126941	39	39	HGNC:644	Treatment of hyperproliferative disorders with diarylhydantoin compounds	The Regents of the University of California	05/02/16	2D 3D TSV
US9120798	50	50	HGNC:8539	Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor	Bristol-Myers Squibb Co.	04/25/16	2D 3D TSV
US9120769	172	171	HGNC:5208	Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline	Boehringer Ingelheim International GmbH	04/25/16	2D 3D TSV
US9120771	46	17	HGNC:11050 HGNC:11048 HGNC:11049	Azetidine derivative and antidepressant composition including the same	Korea Institute of Science and Technology	04/25/16	2D 3D TSV
US9120772	6	3	HGNC:6026 HGNC:6027	Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases	Galderma Research & Development	04/25/16	2D 3D TSV
US9120780	37	37	HGNC:5253	Indole or indazole derivative or salt thereof	Taiho Pharmaceutical Co., Ltd	04/25/16	2D 3D TSV
US9120791	119	115		Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	04/25/16	2D 3D TSV
US9120797	66	27	HGNC:8156 HGNC:21378	Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds	Gruenenthal GmbH	04/25/16	2D 3D TSV
US9120785	12	11	HGNC:11491	Pyridyl aminopyridines as Syk inhibitors	Merck Sharp & Dohme Corp	04/25/16	2D 3D TSV
US9120781	7	7	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Simon Fraser University	04/25/16	2D 3D TSV
US9120807	28	7	HGNC:262 HGNC:263 HGNC:264	Thienopyrimidine compounds	Vernalis (R&D) Ltd	04/25/16	2D 3D TSV
US9120786	14	14	HGNC:10597	Triazine carboxamides as sodium channel blockers	Purdue Pharma LP	04/25/16	2D 3D TSV
US9115121	70	70	HGNC:2160	1,3,5-triazine-2-amine derivatives, preparation thereof and diagnostic and therapeutic use thereof	Sanofi	04/18/16	2D 3D TSV
US9119845	20	20		Method for the treatment of neurological disorders by enhancing the activity of beta-glucocerebrosidase	Amicus Therapeutics, Inc	04/18/16	2D 3D TSV
US9115122	39	8		Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK)	University of Maryland, Baltimore	04/18/16	2D 3D TSV
US9120744	43	38	HGNC:8583	Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism	University of Michigan	04/18/16	2D 3D TSV
US9120752	40	40	HGNC:10597	Pyridine compounds as sodium channel blockers	Purdue Pharma LP	04/18/16	2D 3D TSV
US9120749	650	612	HGNC:16870	Quinoline derivatives and MELK inhibitors containing the same	OncoTherapy Science Inc	04/18/16	2D 3D TSV
US9120761	34	13		Selective FAK inhibitors	Cancer Therapeutics CRC Pty Ltd	04/18/16	2D 3D TSV
US9120756	63	40	HGNC:12716	Substituted phenylureas and phenylamides as vanilloid receptor ligands	Gruenenthal GmbH	04/18/16	2D 3D TSV
US9120745	4	4	HGNC:5258	Triazole compounds that modualte HSP90 activity	Synta Pharmaceuticals Corp.	04/18/16	2D 3D TSV
US9115089	2	1	HGNC:6889 HGNC:6887	Methyl/fluoro-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds and fluoro-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds	Confluence Life Sciences Inc	04/12/16	2D 3D TSV
US9115140	33	20	HGNC:427	Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof	Sanofi	04/12/16	2D 3D TSV
US9115126	10	10	HGNC:2545	1H-[1,2,3]triazolo[4,5-c]pyridine-4-carbonitrile derivatives	Merck Sharp & Dohme B.V.	04/11/16	2D 3D TSV
US9096593	403	61	HGNC:2637 HGNC:6342 HGNC:2625 HGNC:2623 HGNC:2621 HGNC:3765	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	04/11/16	2D 3D TSV
US9115083	75	70		Compounds from Antrodia cinnamomea and use thereof	SIMPSON BIOTECH CO., LTD.	04/11/16	2D 3D TSV
US9115085	1	1	HGNC:1232	Crystalline forms of a prolyl hydroxylase inhibitor	FibroGen Inc	04/11/16	2D 3D TSV
US9115082	9	7	HGNC:3009 HGNC:285 HGNC:286	Dipeptidyl-peptidase-IV inhibitors for treatment of type 2 diabetes complex with hypertension	TBA	04/11/16	2D 3D TSV
US9115116	27	7	HGNC:4852 HGNC:5006 HGNC:14064 HGNC:4853	Dual action inhibitors against histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme a reductase	National Taiwan University	04/11/16	2D 3D TSV
US9115144	5	5		Fused heterocyclic derivative and pharmaceutical use thereof	Kissei Pharmaceutical Co., Ltd	04/11/16	2D 3D TSV
US9115102	45	21	HGNC:195 HGNC:7173 HGNC:216 HGNC:7176 HGNC:7155 HGNC:188	N-[2-hydroxycarbamoyl-2-(piperazinyl) ethyl] benzamide compounds, their preparation and their use as TACE inhibitors	Galderma Research & Development	04/11/16	2D 3D TSV
US9115117	280	98	HGNC:4849 HGNC:4848	Substituted piperidine compounds and their use as orexin receptor modulators	Janssen Pharmaceutica NV	04/11/16	2D 3D TSV
US9102669	100	84		Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors	Janssen Pharmaceutica NV	04/05/16	2D 3D TSV
US9102686	152	45	HGNC:8537	5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocines as P2X7 modulators	Janssen Pharmaceutica NV	04/04/16	2D 3D TSV
US9102591	244	180	HGNC:8537	Benzamides	H. Lundbeck A/S	04/04/16	2D 3D TSV
US9102637	93	93	HGNC:30765	Bicyclic thiazole compounds	Carna Biosciences, Inc	04/04/16	2D 3D TSV
US9102622	63	59		Fatty acid amide hydrolase inhibitors	University of Connecticut	04/04/16	2D 3D TSV
US9096627	6	1	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Hydroxamic acid derivatives	Purdue Pharmaceutical Products L.P.	04/04/16	2D 3D TSV
US9102599	15	15	HGNC:1869	N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases	Bristol-Myers Squibb Co.	04/04/16	2D 3D TSV
US9114126	10	10		Na/K-ATPase ligands, ouabain antagonists, assays and uses thereof	The University of Toledo	04/04/16	2D 3D TSV
US9115061	17	13	HGNC:992	Naphthalene-based inhibitors of anti-apoptotic proteins	Burnham Institute for Medical Research	04/04/16	2D 3D TSV
US9102670	445	440	HGNC:391 HGNC:3942	Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors	KUDOS PHARMACEUTICALS LIMITED	04/04/16	2D 3D TSV
US9102656	12	12	HGNC:5006	Use of rosuvastatin lactols as medicaments	RedX Pharma Limited	04/04/16	2D 3D TSV
US9096559	134	125	HGNC:4852	4-carboxybenzylamino derivatives as histone deacetylase inhibitors	Merck Sharp & Dohme Corp	03/28/16	2D 3D TSV
US9096595	51	51	HGNC:4502	7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators	Actelion Pharmaceuticals Ltd	03/28/16	2D 3D TSV
US9096579	258	175	HGNC:11491	Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments	Boehringer Ingelheim International GmbH	03/28/16	2D 3D TSV
US9238653	54	53		Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	03/28/16	2D 3D TSV
US9096601	108	26	HGNC:6307 HGNC:3236	Arylamino purine derivatives, preparation method and pharmaceutical use thereof	CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.	03/28/16	2D 3D TSV
US9096580	5	5		Benzofuran derivatives for the treatment of hepatitis C	Bristol-Myers Squibb Co.	03/28/16	2D 3D TSV
US9096589	112	111	HGNC:8772	Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	03/28/16	2D 3D TSV
US9096541	28	22	HGNC:934 HGNC:933	Inhibition of memapsin 1 cleavage in the treatment of diabetes	Oklahoma Medical Research Foundation	03/28/16	2D 3D TSV
US9096594	15	5	HGNC:2453 HGNC:2451 HGNC:2452 HGNC:1771 HGNC:4617 HGNC:4616 HGNC:1774	Kinase inhibitors and methods of use thereof	The Broad Institute, Inc.	03/28/16	2D 3D TSV
US9096515	36	12	HGNC:11048 HGNC:11049	Methods of using cycloalkylmethylamine derivatives	Reviva Pharmaceuticals Inc	03/28/16	2D 3D TSV
US9096596	332	111	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	03/28/16	2D 3D TSV
US9096606	64	24	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Quarternized buprenorphine analogs	Purdue Pharma LP	03/28/16	2D 3D TSV
US9096549	46	17	HGNC:4852 HGNC:4854 HGNC:4853	Selective HDAC3 inhibitors	Acetylon Pharmaceuticals Inc	03/28/16	2D 3D TSV
US9089569	190	174	HGNC:436	1,2,6-substituted benzimidazoles as flap modulators	Janssen Pharmaceutica NV	03/21/16	2D 3D TSV
US9090564	130	130	HGNC:3942	5-alkynyl-pyridines	Boehringer Ingelheim International GmbH	03/21/16	2D 3D TSV
US9090562	334	184	HGNC:3527	Aryl- or heteroaryl-substituted benzene compounds	Epizyme Inc	03/21/16	2D 3D TSV
US9090628	126	89	HGNC:8977	Benzoxazepin compounds selective for PI3K P110 delta and methods of use	Genentech Inc	03/21/16	2D 3D TSV
US9090657	22	4	HGNC:40 HGNC:9253 HGNC:53 HGNC:42 HGNC:10959 HGNC:10961	Compound and methods for its production	NEUROVIVE PHARMACEUTICAL AB	03/21/16	2D 3D TSV
US9090596	84	36	HGNC:4540 HGNC:1605 HGNC:1607 HGNC:6026 HGNC:6027	Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies	Galderma Research & Development	03/21/16	2D 3D TSV
US9090589	25	9	HGNC:7872 HGNC:7873	Specific nNOS inhibitors for the therapy and prevention of human melanoma	Northwestern University	03/21/16	2D 3D TSV
US9090618	172	73	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Substituted benzimidazole-type piperidine compounds and uses thereof	Purdue Pharma LP	03/21/16	2D 3D TSV
US9085584	356	121	HGNC:8772	Substituted pyrido[3,2-E][1,2,4]-triazolo[4,3-A]pyrazines for the treatment of central nervous system disorders	Boehringer Ingelheim International GmbH	03/21/16	2D 3D TSV
US9090625	9	9		Therapeutic pyrazolyl thienopyridines	THESAN PHARMACEUTICALS, INC.	03/21/16	2D 3D TSV
US9085572	10	10	HGNC:12687	4-(pyridin-3-yl)-2(pyridin-2yl)-1,2-dihydro-3H-pyrazol-3-one derivatives as specific HIF-pyrolyl-4-hydroxylase inhibitors for treating cardiovascular and haematological diseases	Bayer Intellectual Property GmbH	03/16/16	2D 3D TSV
US9085531	117	36	HGNC:11050 HGNC:11048 HGNC:11049	Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin	Albany Molecular Research, Inc.	03/14/16	2D 3D TSV
US9085555	773	768	HGNC:2771	Complement pathway modulators and uses thereof	Novartis AG	03/14/16	2D 3D TSV
US9085549	48	33	HGNC:11138 HGNC:6893	Compounds for the treatment of neurodegenerative diseases	PROTEOTECH INC	03/14/16	2D 3D TSV
US9079902	124	65	HGNC:10593 HGNC:10597	Heteroaryl sodium channel inhibitors	Amgen Inc	03/14/16	2D 3D TSV
US9085571	30	30		Nonpeptide HIV-1 protease inhibitors	Purdue Research Foundation	03/14/16	2D 3D TSV
US9085576	846	396	HGNC:2529 HGNC:933	Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use	Amgen Inc	03/14/16	2D 3D TSV
US9085540	31	17	HGNC:3236	Pyrazinecarboxamide compound	Astellas Pharma Inc	03/14/16	2D 3D TSV
US9079913	185	172	HGNC:6973	Spiro-oxindole MDM2 antagonists	The Regents of the University of Michigan	03/14/16	2D 3D TSV
US9079929	29	28	HGNC:3529	Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors	Bristol-Myers Squibb Co.	03/14/16	2D 3D TSV
US9073940	429	428	HGNC:8978	Tricyclic pyrazol amine derivatives	Merck Serono	03/09/16	2D 3D TSV
US9079866	833	818	HGNC:436	Flap modulators	Janssen Pharmaceutica NV	03/07/16	2D 3D TSV
US9079834	11	10		HIV protease inhibitors	Merck Canada Inc.	03/07/16	2D 3D TSV
US9073926	105	105	HGNC:10432	Heterocyclic compounds containing a pyrrolopyridine or benzimidazole core	Boehringer Ingelheim International GmbH	03/07/16	2D 3D TSV
US9073939	7	5	HGNC:7029	Indazolyl-substituted dihydroisoxa-zolopyridines and methods of use thereof	Bayer Intellectual Property GmbH	03/07/16	2D 3D TSV
US9073931	108	43	HGNC:7966 HGNC:7965	Liver X receptor modulators	Vitae Pharmaceuticals Inc	03/07/16	2D 3D TSV
US9079852	20	10	HGNC:6251	NMDA receptor antagonists for neuroprotection	Emory University	03/07/16	2D 3D TSV
US9073936	8	4	HGNC:8774	Organic compounds	Intra-Cellular Therapies Inc	03/07/16	2D 3D TSV
US9079880	163	112	HGNC:10252	Rho kinase inhibitors	Boehringer Ingelheim International GmbH	03/07/16	2D 3D TSV
US9079868	1	1	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Simon Fraser University	03/07/16	2D 3D TSV
US9079906	27	27	HGNC:3537	Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments	Sanofi	03/07/16	2D 3D TSV
US9073893	60	24	HGNC:270 HGNC:272	3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitors	Nerviano Medical Sciences srl	02/29/16	2D 3D TSV
US9073870	181	181	HGNC:5208	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use	Boehringer Ingelheim International GmbH	02/29/16	2D 3D TSV
US9073917	27	12	HGNC:11393 HGNC:6058 HGNC:8778	Anti-cancer compound and pharmaceutical composition containing the same	Sanofi	02/29/16	2D 3D TSV
US9073925	10	10	HGNC:4479	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof	Albany Molecular Research, Inc.	02/29/16	2D 3D TSV
US9073881	153	149	HGNC:3287	Benzoic acid derivatives	Hoffmann-La Roche Inc	02/29/16	2D 3D TSV
US9073876	335	332	HGNC:436	Flap modulators	Janssen Pharmaceutica NV	02/29/16	2D 3D TSV
US9073882	9	9	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	02/29/16	2D 3D TSV
US9073869	37	25	HGNC:2528 HGNC:2536	Method of using substituted 2-Aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	02/29/16	2D 3D TSV
US9073911	108	54		Pyrazole derivatives	Hoffmann-La Roche Inc	02/29/16	2D 3D TSV
US9073922	368	368	HGNC:1780 HGNC:8153 HGNC:8154	Pyrrolo[2,3-B]pyridine CDK9 kinase inhibitors	AbbVie Inc	02/29/16	2D 3D TSV
US9073906	44	23	HGNC:5209 HGNC:5208	Sulfamide derivative having an adamantyl group and its pharmaceutically acceptable salt	Korea Research Institute of Chemical Technology	02/29/16	2D 3D TSV
US9067924	24	14		1,4 thiazepines/sulfones as BACE1 and/or BACE2 inhibitors	Hoffmann-La Roche Inc	02/22/16	2D 3D TSV
US9067937	113	113	HGNC:16870	1,5-naphthyridine derivatives and MELK inhibitors containing the same	OncoTherapy Science Inc	02/22/16	2D 3D TSV
US9067931	20	19		2-heteroaryl carboxamides	Bayer Intellectual Property GmbH	02/22/16	2D 3D TSV
US9067949	216	201	HGNC:5301	Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia	Albany Molecular Research, Inc.	02/22/16	2D 3D TSV
US9067922	243	241	HGNC:17989	Chemical compounds	Pfizer Inc	02/22/16	2D 3D TSV
US9073853	157	157	HGNC:4540	Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists	Sanofi	02/22/16	2D 3D TSV
US9062043	371	240	HGNC:270 HGNC:2457	Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators	SENHWA BIOSCIENCES, INC.	02/22/16	2D 3D TSV
US9073821	60	47		Hydroxamic acid derivative	Taisho Pharmaceutical Co., Ltd	02/22/16	2D 3D TSV
US9067935	114	109		Imidazo[1,2-α]pyridine sulfonamides as TRPM8 modulators	Janssen Pharmaceutica NV	02/22/16	2D 3D TSV
US9073833	17	8	HGNC:3309	Oxime-based compound, pharmaceutical composition containing the same and method for preparing the same	Chang Gung University	02/22/16	2D 3D TSV
US9067945	10	1	HGNC:8793 HGNC:8781 HGNC:8792 HGNC:8784 HGNC:8795 HGNC:8773 HGNC:8772 HGNC:8776 HGNC:8779	Selective phosphodiesterase 9A inhibitors as medicaments for improving cognitive processes	Boehringer Ingehleim International GmbH	02/22/16	2D 3D TSV
US9067917	220	215	HGNC:436	1,2,5-substituted benzimidazoles as FLAP modulators	Janssen Pharmaceutica NV	02/16/16	2D 3D TSV
US9067871	405	302	HGNC:11056	Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	02/16/16	2D 3D TSV
US9062066	13	1	HGNC:4840 HGNC:6735 HGNC:3697 HGNC:6307 HGNC:1133 HGNC:3387 HGNC:11491 HGNC:11283 HGNC:12841 HGNC:6524 HGNC:3765	Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases and pharmaceutical composition containing same	Korea Institute of Science and Technology	02/16/16	2D 3D TSV
US9066954	107	107	HGNC:7029	Fused heterocyclic derivatives and methods of use	Amgen Inc	02/16/16	2D 3D TSV
US9067888	20	2	HGNC:1780 HGNC:1772 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:4617 HGNC:4616 HGNC:6112 HGNC:1774	Inhibitors of protein kinases	AstraZeneca AB	02/16/16	2D 3D TSV
US9062070	238	89		Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	02/16/16	2D 3D TSV
US9062059	20	20	HGNC:8772	Pyrimidine PDE10 inhibitors	Merck Sharp & Dohme Corp	02/16/16	2D 3D TSV
US9062078	702	274	HGNC:4849 HGNC:4848	Substituted 7-azabicyles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	02/16/16	2D 3D TSV
US9062060	11	11	HGNC:8772	Substituted imidazo[2,1-A]isoindoles as PDE10 inhibitors	H. Lundbeck A/S	02/16/16	2D 3D TSV
US9067914	241	79	HGNC:8031 HGNC:8032 HGNC:8033	Tropomyosin-related kinase (TRK) inhibitors	Genzyme Corporation	02/16/16	2D 3D TSV
US9061041	6	6		2′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases	Merck Sharp & Dohme Corp	02/09/16	2D 3D TSV
US9062004	58	36	HGNC:2160 HGNC:2159	Cannabinoid-2 agonists	Allergan Inc	02/09/16	2D 3D TSV
US9062048	173	160	HGNC:1612	Cyclohexyl-azetidinyl antagonists of CCR2	Janssen Pharmaceutica NV	02/09/16	2D 3D TSV
US9062026	89	88	HGNC:12666	Fused pyrimidines and substituted quinazolines as inhibitors of p97	Cleave Biosciences, Inc.	02/09/16	2D 3D TSV
US9056859	11	11		Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	02/09/16	2D 3D TSV
US9061023	2	2	HGNC:11285	Management and treatment of benign prostatic hyperplasia	CSIR, Pretoria (ZA)	02/09/16	2D 3D TSV
US9056865	149	149	HGNC:11119	Pyridine-2-derivatives as smoothened receptor modulators	Pfizer Inc	02/09/16	2D 3D TSV
US9056863	3	3		Substituted 2,3,5,9,9B-pentaazacyclopenta[a]naphthalenes and uses thereof	H. Lundbeck A/S	02/09/16	2D 3D TSV
US9062045	143	92	HGNC:7029 HGNC:8779	Triazolopyridine compounds	Novartis AG	02/09/16	2D 3D TSV
US9056843	460	155	HGNC:4852 HGNC:14064 HGNC:14063	Trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease	Novartis AG	02/09/16	2D 3D TSV
US9056847	4	4	HGNC:4177	Activity based probes (ABPs) interacting with glycosidases	ACADEMISCH MEDISCH CENTRUM BIJ UNIVERSITEIT VAN AMSTERDAM	01/25/16	2D 3D TSV
US9051313	18	18	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gildead Sciences, Inc.	01/25/16	2D 3D TSV
US9056836	11	5	HGNC:8154 HGNC:8156	Benzomorphan analogs and the use thereof	Purdue Pharma LP	01/25/16	2D 3D TSV
US9051321	28	27		Heterocyclic acrylamides and their use as pharmaceuticals	Fab Pharma S.A.S.	01/25/16	2D 3D TSV
US9056857	7	7	HGNC:620	Methods for treating or preventing cancer and neurodegenerative diseases	Sloan-Kettering Institute for Cancer Research	01/25/16	2D 3D TSV
US9056832	152	152	HGNC:10597	Pyridine compounds and the users thereof	Purdue Pharma LP	01/25/16	2D 3D TSV
US9051279	174	98	HGNC:6973 HGNC:6974	Substituted isoquinolinones and quinazolinones	Novartis AG	01/25/16	2D 3D TSV
US9051311	173	64	HGNC:10593 HGNC:10597	Sulfamide sodium channel inhibitors	Amgen Inc	01/25/16	2D 3D TSV
US9051280	10	10	HGNC:11056	Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	01/25/16	2D 3D TSV
US9051329	8	8	HGNC:3009	Tricyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors	Merck Sharp & Dohme Corp	01/25/16	2D 3D TSV
US9108973	73	51	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	3,5-disubstituted alkynylbenzene compound and salt thereof	Taiho Pharmaceutical Co., Ltd	01/19/16	2D 3D TSV
US9108978	16	6		Antimicrobial compounds	Monash University	01/19/16	2D 3D TSV
US9108983	174	169	HGNC:990	Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	01/19/16	2D 3D TSV
US9108984	2	2	HGNC:8977	Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors	Incyte Corporation	01/19/16	2D 3D TSV
US9108950	12	1	HGNC:4840 HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl) ureas as p38 MAP kinase inhibitors	Respivert Ltd	01/18/16	2D 3D TSV
US9108956	11	4	HGNC:2843	Cyclic ether DGAT1 inhibitorscyclic ether DGAT1 inhibitors	Novartis AG	01/18/16	2D 3D TSV
US9051265	89	85	HGNC:9236	N-benzylindole modulators of PPARG	The Scripps Research Institute	01/18/16	2D 3D TSV
US9051270	160	157		Pyridone amides as modulators of sodium channels	Vertex Pharmaceuticals Inc	01/18/16	2D 3D TSV
US9051240	7	7		Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators	Newron Pharmaceuticals S.P.A.	01/18/16	2D 3D TSV
US9045501	28	26	HGNC:5297	5-HT3 receptor modulators, methods of making, and use thereof	Albany Molecular Research, Inc.	01/11/16	2D 3D TSV
US9108903	76	74		Amides as modulators of sodium channels	Vertex Pharmaceuticals Inc	01/11/16	2D 3D TSV
US9107954	14	6	HGNC:1606 HGNC:8156	Bivalent ligands for the treatment of neurological disorders	Virginia Commonwealth University	01/11/16	2D 3D TSV
US9107923	81	74	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	01/11/16	2D 3D TSV
US9045498	25	20	HGNC:934 HGNC:933	Hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	01/11/16	2D 3D TSV
US9045500	32	32	HGNC:933	Inhibitors of beta-secretase	Vitae Pharmaceuticals Inc	01/11/16	2D 3D TSV
US9108947	18	17	HGNC:6255	Inhibitors of the Renal Outer Medullary Potassium channel	Merck Sharp & Dohme Corp	01/11/16	2D 3D TSV
US9045524	160	28	HGNC:1507 HGNC:1506 HGNC:1509 HGNC:1508 HGNC:1503 HGNC:1505 HGNC:1504 HGNC:1499 HGNC:1511 HGNC:1500	Selective caspase inhibitors and uses thereof	NOVAGENESIS FOUNDATION	01/11/16	2D 3D TSV
US9108951	16	16	HGNC:3529	Substituted 5,6,7,8-tetrahydro-1,6-naphthyridines as factor XIa inhibitors	Bristol-Myers Squibb Co.	01/11/16	2D 3D TSV
US9108905	19	19	HGNC:497	TRPA1 antagonists	AbbVie Inc	01/11/16	2D 3D TSV
US9045468	186	55	HGNC:11050 HGNC:11048 HGNC:11049	2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin	Albany Molecular Research, Inc.	12/21/15	2D 3D TSV
US9045389	9	9	HGNC:4191	Biphenyl derivatives useful as glucagon receptor antagonists	Janssen Pharmaceutica NV	12/21/15	2D 3D TSV
US9040694	20	6	HGNC:171 HGNC:6307 HGNC:9378	Compounds and methods useful for directing stem cell differentiation	Vanderbilt University	12/21/15	2D 3D TSV
US9040693	15	15	HGNC:4421	Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof	Kissei Pharmaceutical Co., Ltd	12/21/15	2D 3D TSV
US9040727	36	18	HGNC:4853	Histone deacetylase inhibitor of benzamides and use thereof	Shanghai Institute of Pharmaceutical Industry	12/21/15	2D 3D TSV
US9040691	47	40	HGNC:175	Hydroxymethylaryl-substituted pyrrolotriazines as ALK1 inhibitors	Bayer Intellectual Property GmbH	12/21/15	2D 3D TSV
US9040714	139	137	HGNC:3449	IRE-1α inhibitors	MannKind Corporation	12/21/15	2D 3D TSV
US9045483	13	13	HGNC:30661	Inhibition of small ubiquitin-like modifier enzymes with substituted pyrrolo[2,3-b]quinoxalines	City of Hope	12/21/15	2D 3D TSV
US9045459	3	3	HGNC:11056	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Deutschland GmbH & Co. KG	12/21/15	2D 3D TSV
US9040717	10	6	HGNC:8809 HGNC:8810	Pyrazole-amide compounds and pharmaceutical use thereof	Japan Tobacco Inc	12/21/15	2D 3D TSV
US9040518	72	72	HGNC:10906	Chemical compounds	GlaxoSmithKline	12/14/15	2D 3D TSV
US9040528	203	190		Chemical compounds 542	AstraZeneca AB	12/14/15	2D 3D TSV
US9040501	5	5	HGNC:1712	Compositions and methods for treating cancer	Otsuka Pharmaceutical Co., Ltd	12/14/15	2D 3D TSV
US9040663	202	116	HGNC:6932 HGNC:6929	Melanocortin receptor-specific peptides	AstraZeneca AB	12/14/15	2D 3D TSV
US9040509	6	3	HGNC:3467 HGNC:3468	Method of treating human skin and a skin care composition for use in such a method	Pantarhei Bioscience B.V.	12/14/15	2D 3D TSV
US9035059	157	143	HGNC:23248	Nitrogen-containing condensed heterocyclic compound	Taisho Pharmaceutical Co., Ltd	12/14/15	2D 3D TSV
US9035074	168	42	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrrolo[2,3-D]pyrimidine derivatives	Pfizer Inc	12/14/15	2D 3D TSV
US9040542	2	1		Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pryimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea	Vertex Pharmaceuticals Inc	12/14/15	2D 3D TSV
US9040534	279	90	HGNC:8537	[1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators	Janssen Pharmaceutica NV	12/14/15	2D 3D TSV
US9034921	203	202	HGNC:11037	Diphenylmethane derivatives as SGLT2 inhibitors	Green Cross Corporation	12/08/15	2D 3D TSV
US9035066	3	3	HGNC:550	Method of using 4,5,6,7-tetrahydroimidazo[4,5-C]pyridine compounds	Proximagen Limited	12/08/15	2D 3D TSV
US9035062	3	3		Process for preparing a compound useful for producing an optically active diazabicyclooctane compound	Meiji Seika Pharma Co., Ltd	12/08/15	2D 3D TSV
US9034856	51	14	HGNC:644 HGNC:8910	17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative	Bayer Intellectual Property GmbH	12/07/15	2D 3D TSV
US9034886	5	5	HGNC:4852	4-aminoquinazoline derivatives and uses thereof	Shanghai Institute of Pharmaceutical Industry	12/07/15	2D 3D TSV
US9034574	20	12	HGNC:6917 HGNC:6990	Agents for reversing epigenetic silencing of genes	The Johns Hopkins University	12/07/15	2D 3D TSV
US9034899	81	26	HGNC:11050 HGNC:11048 HGNC:11049	Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof	Albany Molecular Research, Inc.	12/07/15	2D 3D TSV
US9034874	20	10	HGNC:5184	Carbamate/urea derivatives	Novartis AG	12/07/15	2D 3D TSV
US9034897	44	44	HGNC:6278	Indanyl-substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-C]pyridines, their use as medicament, and pharmaceutical preparations comprising them	Sanofi	12/07/15	2D 3D TSV
US9034907	36	36	HGNC:9753	Inhibitors of glutaminyl cyclase	Probiodrug AG	12/07/15	2D 3D TSV
US9034866	815	608	HGNC:6853	Tricyclic compounds and methods of use therefor	Genentech Inc	12/07/15	2D 3D TSV
US9029399	54	50	HGNC:2593	17α-hydroxylase/C17,20-lyase inhibitors	Novartis AG	11/23/15	2D 3D TSV
US9029364	34	17	HGNC:4849 HGNC:4848	2,5-disubstituted thiomorpholine orexin receptor antagonists	Merck Sharp & Dohme Corp	11/23/15	2D 3D TSV
US9029393	22	22	HGNC:263	Adenosine receptor ligands and uses thereof	Kaldi Pharma, SAS	11/23/15	2D 3D TSV
US9029381	55	32	HGNC:5184	Cyclopropyl amide derivatives	AstraZeneca AB	11/23/15	2D 3D TSV
US9029362	23	10	HGNC:934 HGNC:933	Iminothiadiazine dioxide compounds as brace inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	11/23/15	2D 3D TSV
US9034303	10	5	HGNC:6833 HGNC:6834	Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof	TBA	11/23/15	2D 3D TSV
US9034854	6	3	HGNC:3467 HGNC:3468	Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy	Pantarhei Bioscience B.V.	11/23/15	2D 3D TSV
US9029401	58	30	HGNC:9829 HGNC:3402	Sorafenib derivatives as sEH inhibitors	The Regents of the University of California	11/23/15	2D 3D TSV
US9029370	276	138		Substituted benzamide derivatives	Hoffmann-La Roche Inc	11/23/15	2D 3D TSV
US9023767	2	2	HGNC:28042	γ-Secretase substrates and methods of use	Memorial Sloan-Kettering Cancer Center	11/16/15	2D 3D TSV
US9023882	212	212		5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same	Kissei Pharmaceutical Co., Ltd	11/16/15	2D 3D TSV
US9029367	5	5	HGNC:933	BACE inhibitors	Eli Lilly and Company	11/16/15	2D 3D TSV
US9023865	687	655	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp	11/16/15	2D 3D TSV
US9024044	162	81	HGNC:9490 HGNC:9475	Heteroarylcarboxylic acid ester derivative	Ajinomoto Co. Inc	11/16/15	2D 3D TSV
US9029360	36	19	HGNC:4597 HGNC:5208	Pyrazolopyrimidines as metabotropic glutamate 5 receptor antagonists	Boehringer Ingelheim International GmbH	11/16/15	2D 3D TSV
US9023849	22	22	HGNC:8784	Substituted fused imidazoles and pyrazoles and use thereof	Bayer Intellectual Property GmbH	11/16/15	2D 3D TSV
US9029356	12	4	HGNC:5465 HGNC:11390 HGNC:427	Substituted indazole derivatives active as kinase inhibitors	Nerviano Medical Sciences srl	11/16/15	2D 3D TSV
US9018371	27	15	HGNC:262 HGNC:263	Adenosine derivatives, method for the synthesis thereof, and the pharmaceutical compositions for the prevention and treatment of the inflammatory diseases containing the same as an active ingredient	FM Therapeutics Co., Ltd.	11/11/15	2D 3D TSV
US9018381	66	32	HGNC:992 HGNC:990	Chemical compounds	AstraZeneca AB	11/11/15	2D 3D TSV
US9023354	43	42	HGNC:6973	Combination therapy with MDM2 and EFGR inhibitors	TBA	11/11/15	2D 3D TSV
US9018217	124	124	HGNC:8772	Phenylimidazole derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	11/11/15	2D 3D TSV
US9029559	503	500	HGNC:9251	Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals	Sanofi	11/11/15	2D 3D TSV
US9018213	12	6		Alicyclic[c] benzopyrone derivatives and uses thereof	Huazhong University of Science & Technology	11/02/15	2D 3D TSV
US9018214	370	217	HGNC:590 HGNC:592	Bicyclic heterocycle compounds and their uses in therapy	Astex Therapeutics Limited	11/02/15	2D 3D TSV
US9011882	20	20	HGNC:2715	Dimethylarginine dimethylaminohydrolase inhibitors and methods of use thereof	The Board of Trustees of the Leland Stanford Junior University	11/02/15	2D 3D TSV
US9018255	7	7	HGNC:12437	Esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin—thioredoxin reductase system	Instytut Chemii Organicznej Polskiej Akademii Nauk	11/02/15	2D 3D TSV
US9012461	132	38	HGNC:9611	FAK inhibitors	Cancer Therapeutics CRC Pty Ltd	11/02/15	2D 3D TSV
US9018234	8	7	HGNC:7029	Fluoro-substituted 2-aryl-3,5-dicyano-4-indazolyl-6-methyl-1,4-dihydropyridines and uses thereof	Bayer Intellectual Property GmbH	11/02/15	2D 3D TSV
US9018391	16	16	HGNC:933	Inhibitors of beta-secretase	Boehringer Ingelheim International GmbH	11/02/15	2D 3D TSV
US9018211	9	9		Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	11/02/15	2D 3D TSV
US9012475	26	13	HGNC:11393 HGNC:11390	Method for enhancing anti-tumor effect of a microtubule-targeting drug, and a method for treatment of tumor	Taiho Pharmaceutical Co., Ltd	11/02/15	2D 3D TSV
US9012651	291	291	HGNC:18084	TRPV3 modulators	AbbVie Inc	11/02/15	2D 3D TSV
US9006269	19	19	HGNC:3553	Azetidine derivatives	Vernalis (R&D) Ltd	10/26/15	2D 3D TSV
US9006454	111	110	HGNC:2867	Dihydroorotate dehydrogenase inhibitors	Merck Serono	10/26/15	2D 3D TSV
US9006244	14	7	HGNC:7966 HGNC:7965	Liver X receptor modulators	Vitae Pharmaceuticals Inc	10/26/15	2D 3D TSV
US9006283	6	6		Methods of modifying amyloid β oligomers using non-peptidic compounds	Acumen Pharmaceuticals, Inc.	10/26/15	2D 3D TSV
US9006268	10	10	HGNC:9344	Prolylcarboxypeptidase inhibitors	Merck Sharp & Dohme Corp	10/26/15	2D 3D TSV
US9006232	98	98		Pyrimidone derivatives	Mitsubishi Tanabe Pharma Corporation	10/26/15	2D 3D TSV
US9006282	20	20		Rosuvastatin and atorvastatin derivatives	RedX Pharma Limited	10/26/15	2D 3D TSV
US9006249	13	13	HGNC:7154	Substituted aminobutyric derivatives as neprilysin inhibitors	Novartis AG	10/26/15	2D 3D TSV
US9006242	15	3	HGNC:2595 HGNC:2625 HGNC:2622 HGNC:2623 HGNC:2621	Substituted benzene compounds	Epizyme Inc	10/26/15	2D 3D TSV
US9006246	15	15	HGNC:3357	Tetrahydrocarboline derivative	Ono Pharmaceutical Co., Ltd	10/26/15	2D 3D TSV
US9000182	41	24	HGNC:933 HGNC:620	2H-imidazol-4-amine compounds and their use as BACE inhibitors	AstraZeneca AB	10/19/15	2D 3D TSV
US9000185	18	10	HGNC:933 HGNC:620	Cycloalkyl ether compounds and their use as BACE inhibitors	AstraZeneca AB	10/19/15	2D 3D TSV
US9000183	21	12	HGNC:933 HGNC:620	Cyclohexane-1,2′-indene-1′,2″-imidazol compounds and their use as BACE inhibitors	AstraZeneca AB	10/19/15	2D 3D TSV
US9000184	31	17	HGNC:933 HGNC:620	Cyclohexane-1,2′-naphthalene-1′,2″-imidazol compounds and their use as BACE inhibitors	AstraZeneca AB	10/19/15	2D 3D TSV
US8999957	459	315		Heterocyclic compounds as ERK inhibitors	Merck Sharp & Dohme Corp	10/19/15	2D 3D TSV
US9000153	43	43	HGNC:9413	Imidazo[4,5-c]quinolines as DNA-PK inhibitors	Merck Patent GmbH	10/19/15	2D 3D TSV
US9000043	4	1	HGNC:9594 HGNC:9593 HGNC:9596 HGNC:9595	Phenoxyethoxy compounds	Eli Lilly and Company	10/19/15	2D 3D TSV
US9000029	118	59	HGNC:4849 HGNC:4848	Proline sulfonamide derivatives as orexin receptor antagonists	Actelion Pharmaceuticals Ltd	10/19/15	2D 3D TSV
US9000044	67	61	HGNC:4502	Substituted naphthylacetic acids	Hoffmann-La Roche Inc	10/19/15	2D 3D TSV
US9006187	34	34	HGNC:11037	Thiophene derivative as SGLT2 inhibitor and pharmaceutical composition comprising same	Green Cross Corporation	10/19/15	2D 3D TSV
US8999981	252	240	HGNC:9395	3-amido-pyrrolo[3,4-C]pyrazole-5(1H, 4H,6H) carbaldehyde derivatives	Pfizer Inc	10/12/15	2D 3D TSV
US9012443	827	500	HGNC:10593 HGNC:10597	Bicyclic aryl and heteroaryl sodium channel inhibitors	Amgen Inc	10/12/15	2D 3D TSV
US9000008	5	5		Amides of acetic and propionic acids	Bayer Intellectual Property GmbH	10/05/15	2D 3D TSV
US9000015	42	14	HGNC:6833 HGNC:6834 HGNC:404	Compounds for the treatment of addiction	Gilead Sciences Inc	10/05/15	2D 3D TSV
US8999994	36	9		Derivatives of propargylamine having neuroprotective capacity for the treatment of Alzheimer's and Parkinson's diseases	Consejo Superior de Investigaciones Cientificas	10/05/15	2D 3D TSV
US8999980	19	19	HGNC:933	Oxazine derivatives	Shionogi & Co., Ltd	10/05/15	2D 3D TSV
US8999982	16	16		Pharmaceutically active compounds as Axl inhibitors	Lead Discovery Center GmbH	10/05/15	2D 3D TSV
US8993808	181	65	HGNC:6833 HGNC:6834 HGNC:29079	Phenylcyclopropylamine derivatives and their medical use	Oryzon Genomics, S.A.	10/05/15	2D 3D TSV
US8999998	95	24	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolopyrimidine JAK inhibitor compounds and methods	Genentech Inc	10/05/15	2D 3D TSV
US8999975	140	138	HGNC:2528	Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	10/05/15	2D 3D TSV
US8999955	14	5	HGNC:1722 HGNC:1774	Tetrahydrocyclopenta[c]acridine derivatives as kinase inhibitors and biological	Centre National de la Recherche Scientifique	10/05/15	2D 3D TSV
US8993616	113	113		(aza)indole derivative and use thereof for medical purposes	Kissei Pharmaceutical Co., Ltd	09/28/15	2D 3D TSV
US8993596	3	3		4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics	Galderma Research & Development	09/28/15	2D 3D TSV
US8993631	43	42	HGNC:14668	Method of treating contrast-induced nephropathy	Novartis AG	09/28/15	2D 3D TSV
US8993612	10	10	HGNC:25896	Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer	Rhizen Pharmaceuticals SA	09/28/15	2D 3D TSV
US8993568	6	5	HGNC:23248	Morpholinyl derivatives useful as MOGAT-2 inhibitors	Eli Lilly and Company	09/28/15	2D 3D TSV
US8993586	248	124	HGNC:85 HGNC:84	N1/N2-lactam acetyl-CoA carboxylase inhibitors	Pfizer Inc	09/28/15	2D 3D TSV
US8993756	226	112	HGNC:6192 HGNC:6193	Pyrrolopyrimidines as janus kinase inhibitors	Merck Sharp & Dohme Corp	09/28/15	2D 3D TSV
US8993614	52	48	HGNC:6973	Substituted pyrrolidine-2-carboxamides	F. Hoffmann-La Roche Inc	09/28/15	2D 3D TSV
US8993765	26	26	HGNC:4479	Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof	Albany Molecular Research, Inc.	09/28/15	2D 3D TSV
US8993575	12	6		[1,3,4] oxadiazole derivative and application thereof	Huazhong University of Science & Technology	09/28/15	2D 3D TSV
US8993565	161	153	HGNC:391	(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives, preparation thereof and pharmaceutical use thereof as AKT(PKB) phosphorylation inhibitors	Sanofi	09/03/15	2D 3D TSV
US8993552	72	64	HGNC:7010	Compositions and methods for treatment of leukemia	University of Michigan	09/03/15	2D 3D TSV
US8987474	133	124	HGNC:9670 HGNC:9673 HGNC:9642 HGNC:9644 HGNC:9659 HGNC:9658	Inhibition of Shp2/PTPN11 protein tyrosine phosphatase by NSC-87877, NSC-117199 and their analogs	University of South Florida	09/03/15	2D 3D TSV
US8993557	10	10	HGNC:6623	Pyridinedione carboxamide inhibitors of endothelial lipase	Bristol-Myers Squibb Co.	09/03/15	2D 3D TSV
US8993556	18	18	HGNC:5253	Resorcinol derivatives as HSP90 inhibitors	Nerviano Medical Sciences srl	09/03/15	2D 3D TSV
US8987473	72	72	HGNC:17989	Ring-fused compound	Sato Pharmaceutical Co., Ltd.	09/03/15	2D 3D TSV
US8987457	595	202	HGNC:19310 HGNC:8987	Ring-substituted N-pyridinyl amides as kinase inhibitors	Novartis AG	09/03/15	2D 3D TSV
US8987319	37	37	HGNC:644	Selective androgen receptor modulators	Radius Health, Inc.	09/03/15	2D 3D TSV
US8987335	35	26	HGNC:6833 HGNC:6834 HGNC:29079	Substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors	University of Utah Research Foundation	09/03/15	2D 3D TSV
US8987445	181	180	HGNC:17961	Sulfonamide compounds having TRPM8 antagonistic activity	Mitsubishi Tanabe Pharma Corporation	09/03/15	2D 3D TSV
US8987314	725	375	HGNC:6619 HGNC:6623	Amide, urea or sulfone amide linked benzothiazole inhibitors of endothelial lipase	Bristol-Myers Squibb Co.	08/25/15	2D 3D TSV
US8987272	3	3		Compounds and method for treatment of HIV	Critical Outcome Technologies Inc.	08/25/15	2D 3D TSV
US8987257	68	38	HGNC:8975 HGNC:3942	Heterocyclic derivatives	Novartis AG	08/25/15	2D 3D TSV
US8987313	34	17	HGNC:2637	Inhibitors of cytochrome P450	Gilead Sciences Inc	08/25/15	2D 3D TSV
US8987315	20	5	HGNC:2593 HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Innocrin Pharmaceuticals, Inc.	08/25/15	2D 3D TSV
US8981106	177	177	HGNC:6027	Pyrimidinecarboxamides as CXCR2 modulators	Syntrix Biosystems, Inc.	08/25/15	2D 3D TSV
US8987268	121	60	HGNC:6190 HGNC:6193	Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases	Bristol-Myers Squibb Co.	08/25/15	2D 3D TSV
US8987287	25	12	HGNC:8153 HGNC:8154 HGNC:8156	Spirocyclic morphinans and their use	Purdue Pharma LP	08/25/15	2D 3D TSV
US8987273	75	38	HGNC:391 HGNC:392	Substituted imidazo[1,2-B]pyridazines	Bayer Intellectual Property GmbH	08/25/15	2D 3D TSV
US8987286	45	45	HGNC:391	Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathway	Bayer Intellectual Property GmbH	08/25/15	2D 3D TSV
US8987239	20	10	HGNC:644 HGNC:8910	19-nor-steroid derivatives with a 15α,16α-methylene group and a saturated 17,17-spirolactone ring, use thereof, and medicaments containing said derivatives	Bayer Intellectual Property GbmH	08/19/15	2D 3D TSV
US8980938	7	7	HGNC:6027	CXCR2 inhibitors	Sanofi	08/19/15	2D 3D TSV
US8980932	40	10	HGNC:1373 HGNC:1383 HGNC:1371 HGNC:1368	Cancer targeting using carbonic anhydrase isoform IX inhibitors	Maastro-Clinic	08/19/15	2D 3D TSV
US8981112	25	25	HGNC:933	Inhibitors of β-secretase	Vitae Pharmaceuticals Inc	08/19/15	2D 3D TSV
US8987247	3	1	HGNC:17038	Monoacylglycerol lipase inhibitors for the treatment of metabolic diseases and related disorders	Janssen Pharmaceutica NV	08/19/15	2D 3D TSV
US8987242	15	15	HGNC:3551	Morpholinone compounds as factor IXA inhibitors	Merck Sharp & Dohme Corp	08/19/15	2D 3D TSV
US8987249	358	357	HGNC:2528	Substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C	Boehringer Ingelheim International GmbH	08/19/15	2D 3D TSV
US8980954	13	13	HGNC:9955	Substituted cis- and trans-stilbenes as therapeutic agents	STC.UNM	08/19/15	2D 3D TSV
US8987248	26	25	HGNC:3537	Substituted piperidines as Par-1 antagonists	Bayer Intellectual Property GmbH	08/19/15	2D 3D TSV
US8987254	8	8	HGNC:933	Tetrahydropyrrolothiazine compounds	Eli Lilly and Company	08/19/15	2D 3D TSV
US8980887	7	7		2-aryl imidazo[1,2-a]pyridine-3-acetamide derivatives, preparation methods and uses thereof	Toxicology Academy of Military Medical Sciences P.L.A.	08/10/15	2D 3D TSV
US8980901	5	5	HGNC:8977	5-fluoro-3-phenyl-2[1-(9H-purin-6-ylamino)propyl]-3H-quinazolin-4-one and 6-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)ethyl]-3H-quinazolin-4-one as inhibitors of human phosphatidylinositol 3-kinase delta	ICOS Corporation	08/10/15	2D 3D TSV
US8980829	56	25	HGNC:11037 HGNC:11036	Aryl glycoside compound, preparation method and use thereof	Shanghai Yingli Science and Technology Co., Ltd	08/10/15	2D 3D TSV
US8980905	10	10	HGNC:8780	Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors	Leo Pharma A/S	08/10/15	2D 3D TSV
US8975415	367	211	HGNC:6251 HGNC:933	Chromane compounds	CoMentis Inc	08/10/15	2D 3D TSV
US8980916	3	3	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	08/10/15	2D 3D TSV
US8980904	18	18	HGNC:8784	Heterocyclic substituted pyrimidine compound	Xuanzhu Pharma Co., Ltd	08/10/15	2D 3D TSV
US8975409	18	9	HGNC:3169	Phenyl derivative	Ono Pharmaceutical Co., Ltd	08/10/15	2D 3D TSV
US8975417	716	189	HGNC:13575 HGNC:1103 HGNC:2348 HGNC:1104	Pyrazolopyrrolidine derivatives and their use in the treatment of disease	Novartis AG	08/10/15	2D 3D TSV
US8980906	50	27	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Pyridonemorphinan analogs and biological activity on opioid receptors	Purdue Pharma LP	08/10/15	2D 3D TSV
US8980929	14	13	HGNC:3009	Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes	Merck Sharp & Dohme Corp	08/10/15	2D 3D TSV
US8975250	13	13	HGNC:1462	5 oxo-5,8-dihydropyrido[2,3-d]pyrimidine derivatives as CaMKII kinase inhibitors for treating cardiovascular diseases	Sanofi	08/03/15	2D 3D TSV
US8975261	14	14	HGNC:8772	Aryloxmethyl cyclopropane derivatives as PDE10 inhibitors	Merck Sharp & Dohme Corp	08/03/15	2D 3D TSV
US8975249	94	45	HGNC:3236	Heterocyclic compounds and uses thereof	Celgene Avilomics Research, Inc.	08/03/15	2D 3D TSV
US8975276	8	8	HGNC:8772	Inhibitors of PDE10	Bristol-Myers Squibb Co.	08/03/15	2D 3D TSV
US8962860	19	19	HGNC:9753	Inhibitors of glutaminyl cyclase	Probiodrug AG	08/03/15	2D 3D TSV
US8975247	27	27	HGNC:6251	Methods and compositions of treating a flaviviridae family viral infection	The Board of Trustees of the Leland Stanford Junion University	08/03/15	2D 3D TSV
US8975252	2	2	HGNC:9958	Morpholine derivative	Shanghai Pharmaceuticals Holding Co., Ltd.	08/03/15	2D 3D TSV
US8975260	12	12	HGNC:1133	Pyridazinones, method of making, and method of use thereof	Genetech, Inc	08/03/15	2D 3D TSV
US8975265	371	189	HGNC:391 HGNC:392	Substituted imidazo[1,2-a]pyrimidines and —pyridines	Bayer Intellectual Property GmbH	08/03/15	2D 3D TSV
US8975282	8	4	HGNC:6307 HGNC:7029	Substituted pyrazolone compounds and methods of use	Sunshine Lake Pharma Co., Ltd	08/03/15	2D 3D TSV
US8975267	51	17	HGNC:12401 HGNC:8987	Tricyclic pyrrolo derivatives, process for their preparation and their use as kinase inhibitors	Nerviano Medical Sciences srl	08/03/15	2D 3D TSV
US8962637	76	42	HGNC:6190 HGNC:6192 HGNC:11283	Bicyclic compounds and their uses as dual c-SRC/JAK inhibitors	Debiopharm S.A.	07/22/15	2D 3D TSV
US8962651	8	8		Compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	07/22/15	2D 3D TSV
US8962674	93	92	HGNC:933	Curcumin derivative	Tokyo Institute of Technology	07/22/15	2D 3D TSV
US8962837	24	24	HGNC:10571	Nitrogen heterocycle derivatives, preparation thereof and application thereof in human therapeutics	Pierre Fabre Medicament	07/22/15	2D 3D TSV
US8962646	38	13	HGNC:8153 HGNC:8154 HGNC:8156	Peripherally acting opioid compounds	Alkermes, Inc.	07/22/15	2D 3D TSV
US8962659	4	1	HGNC:9594 HGNC:9593 HGNC:9596 HGNC:9595	Phenoxyethyl piperidine compounds	Eli Lilly and Company	07/22/15	2D 3D TSV
US8962641	490	483	HGNC:85	Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	07/22/15	2D 3D TSV
US8962630	205	97	HGNC:1771 HGNC:1722 HGNC:1773	Pyrrolopyrimidine compounds and their uses	Novartis AG	07/22/15	2D 3D TSV
US8962664	3	3	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Simon Fraser University	07/22/15	2D 3D TSV
US8962859	12	11	HGNC:933	Spiro-amino-imidazo-fused heterocyclic compounds as beta-secretase modulators and methods of use	Amgen Inc	07/22/15	2D 3D TSV
US8962648	231	223	HGNC:18282	Tricyclic compounds and PBK inhibitors containing the same	OncoTherapy Science Inc	07/22/15	2D 3D TSV
US8957084	9	5	HGNC:8154 HGNC:8156	7,8-cyclicmorphinan analogs	Purdue Pharma LP	07/15/15	2D 3D TSV
US8957219	12	12	HGNC:6623	Acetic acid amide derivative having inhibitory activity on endothelial lipase	Shionogi & Co., Ltd	07/15/15	2D 3D TSV
US8957103	18	5	HGNC:6307 HGNC:4617 HGNC:3765	Conjugated 3-(indolyl)- and 3-(azaindolyl)-4-arylmaleimide compounds and their use in tumor treatment	Johannes Gutenberg—Universitat Mainz	07/15/15	2D 3D TSV
US8962608	1192	563	HGNC:6190 HGNC:6192	Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors	Merck Sharp & Dohme Corp	07/15/15	2D 3D TSV
US8962616	41	22	HGNC:934 HGNC:933	Heterocyclic substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	07/15/15	2D 3D TSV
US8957093	262	261	HGNC:9236	N-biphenylmethylindole modulators of PPARG	The Scripps Research Institute	07/15/15	2D 3D TSV
US8962609	129	72	HGNC:11584 HGNC:14552	Pyrimidine compounds as inhibitors of protein kinases IKK epsilon and/or TBK-1, processes for their preparation, and pharmaceutical compositions containing them	Domainex Limited	07/15/15	2D 3D TSV
US8962611	356	270	HGNC:6973	Substituted imidazopyridines as HDM2 inhibitors	Merck Sharp & Dohme Corp	07/15/15	2D 3D TSV
US8962619	36	20	HGNC:391	Substituted imidazopyridinyl-aminopyridine compounds	ArQule Inc	07/15/15	2D 3D TSV
US8962612	20	20	HGNC:5300	Tetrahydroisoquinoline derivative	Astellas Pharma Inc	07/15/15	2D 3D TSV
US8957075	28	26	HGNC:8127	O-GlcNAc transferase inhibitors and uses thereof	President and Fellows of Harvard College	07/10/15	2D 3D TSV
US8957077	14	14	HGNC:8772	Pyrazolopyrimidine PDE 10 inhibitors	Merck Sharp & Dohme Corp	07/10/15	2D 3D TSV
US8957074	298	144	HGNC:1722 HGNC:1773	Pyrrolopyrimidine compounds as inhibitors of CDK4/6	Novartis AG	07/10/15	2D 3D TSV
US8957083	31	29	HGNC:933	Spiro-amino-imidazolone and spiro-amino-dihydro-pyrimidinone compounds as beta-secretase modulators and methods of use	Amgen Inc	07/10/15	2D 3D TSV
US8957068	870	504	HGNC:5382	3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH	Novartis AG	07/09/15	2D 3D TSV
US8957064	185	91	HGNC:391 HGNC:392	Fused pyrimidines	Bayer Intellectual Property GmbH	07/09/15	2D 3D TSV
US8957059	66	66		Modulators of serotonin receptors	Janssen Pharmaceutica NV	07/09/15	2D 3D TSV
US8957073	378	372	HGNC:8772	Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors	Amgen Inc	07/09/15	2D 3D TSV
US8957057	4	1	HGNC:7978 HGNC:644 HGNC:3467 HGNC:8910	Use of azaphilone compounds for the modulation of the activity of a nuclear hormone receptor	Food Industry Research and Development Institute	07/09/15	2D 3D TSV
US8952177	191	177	HGNC:436	1,2,6-substituted benzimidazoles as FLAP modulators	Janssen Pharmaceutica NV	06/29/15	2D 3D TSV
US8952157	407	404	HGNC:990	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	06/29/15	2D 3D TSV
US8952036	5	5	HGNC:2637	Benzoic acid derivative MDM2 inhibitor for the treatment of cancer	Amgen Inc	06/29/15	2D 3D TSV
US8952037	98	93	HGNC:8772	Heteroaryloxycarbocyclyl compounds as PDE10 inhibitors	Amgen Inc	06/29/15	2D 3D TSV
US8956589	22	22	HGNC:620	Imaging diagnostic agent and extracorporeal diagnostic agent for incurable neurological diseases	Shiga University of Medical Science	06/29/15	2D 3D TSV
US8952027	12	3	HGNC:15916 HGNC:6735 HGNC:3697 HGNC:11491 HGNC:11283 HGNC:6861 HGNC:12841 HGNC:6524 HGNC:3765	Inhibitors of syk and JAK protein kinases	Portola Pharmaceuticals Inc	06/29/15	2D 3D TSV
US8952025	3	3		Multifunctional radical quenchers and their uses	Arizona Board of Regents, A Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University	06/29/15	2D 3D TSV
US8952169	708	407	HGNC:10593 HGNC:10597	N-substituted benzamides and methods of use thereof	Xenon Pharmaceuticals Inc	06/29/15	2D 3D TSV
US8952150	30	28		Prostaglandin transporter inhibitors and uses thereof	Albert Einstein College of Medicine of Yeshiva University	06/29/15	2D 3D TSV
US8952128	168	49	HGNC:3023 HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin-dopamine chimeric analogs	Ipsen Pharma S.A.S.	06/29/15	2D 3D TSV
US8969583	55	29	HGNC:3763 HGNC:6307 HGNC:8804	3-phenyl-5-ureidoisothiazole-4-carboximide and 3-amino-5-phenylisothiazole derivatives as kinase inhibitors	Allergan Inc	06/22/15	2D 3D TSV
US8952002	3	3	HGNC:7029	Aminoheteroaryl compounds and preparation method and use thereof	Shanghai Allist Pharmaceuticals, Inc.	06/22/15	2D 3D TSV
US8969358	54	38	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Buprenorphine analogs	Purdue Pharma LP	06/22/15	2D 3D TSV
US8952008	50	50	HGNC:4076	Chemical compounds	Pfizer Inc	06/22/15	2D 3D TSV
US8969348	10	10	HGNC:2097	Chymase inhibitors	Boehringer Ingelheim International GmbH	06/22/15	2D 3D TSV
US8969336	95	50	HGNC:10261 HGNC:9967 HGNC:3765	Diamino heterocyclic carboxamide compound	Astellas Pharma Inc	06/22/15	2D 3D TSV
US8969578	13	13	HGNC:11364	Inhibitors of STAT3	University of Central Florida Research Foundation, Inc.	06/22/15	2D 3D TSV
US8969376	43	43	HGNC:8772	Pyrazolopyrimidine compounds and their use as PDE10 inhibitors	Mitsubishi Tanabe Pharma Corporation	06/22/15	2D 3D TSV
US8969586	18	18	HGNC:2593	Substituted bicyclic heteroaryl compounds	Bristol-Myers Squibb Co.	06/22/15	2D 3D TSV
US8969568	125	115	HGNC:11491	Substituted naphthyridines and their use as medicaments	Boehringer Ingelheim Pharma GmbH & Co. KG	06/22/15	2D 3D TSV
US8969333	6	6	HGNC:20449	Therapeutic compositions and methods	The Penn State Research Foundation	06/22/15	2D 3D TSV
US8969394	24	24	HGNC:9596	Thiophenecarboxamide derivatives as EP4 receptor ligands	Merck Frosst Canada Ltd	06/22/15	2D 3D TSV
US8969335	189	95	HGNC:11584 HGNC:14552	Benzonitrile derivatives as kinase inhibitors	Merck Patent GmbH	06/16/15	2D 3D TSV
US8940739	190	187	HGNC:2637	Compound of a reverse-turn mimetic and a production method and use therefor	JW Pharmaceutical Corporation	06/16/15	2D 3D TSV
US8940893	17	17	HGNC:1133	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	06/16/15	2D 3D TSV
US8940748	21	11	HGNC:934 HGNC:933	Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	06/16/15	2D 3D TSV
US8940720	77	77	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Co.	06/16/15	2D 3D TSV
US8940771	29	29	HGNC:8975	Organic compounds	Novartis AG	06/16/15	2D 3D TSV
US8940744	33	33	HGNC:1133	Pyrazolopyrimidine compounds as kinase inhibitors	Principia Biopharma Inc	06/16/15	2D 3D TSV
US8969341	345	199	HGNC:6973 HGNC:6974	Pyrazolopyrrolidine compounds	Novartis AG	06/16/15	2D 3D TSV
US8969352	164	47	HGNC:4849 HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	Janssen Pharmaceutica NV	06/16/15	2D 3D TSV
US8969325	333	331	HGNC:12716	TRPV1 antagonists	AbbVie Inc	06/16/15	2D 3D TSV
US8937070	24	4	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11491	Inhibitors of protein kinases	Portola Pharmaceuticals Inc	06/15/15	2D 3D TSV
US8937058	38	19	HGNC:644 HGNC:8910	17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivative, use thereof, and medicament containing the derivative	TBA	06/08/15	2D 3D TSV
US8937095	12	6	HGNC:6840	Anticancer compounds	Boehringer Ingelheim International GmbH	06/08/15	2D 3D TSV
US8937193	50	12	HGNC:6943 HGNC:992 HGNC:990 HGNC:991	Apogossypolone derivatives as anticancer agents	Sanford-Burnham Medical Research Institute	06/08/15	2D 3D TSV
US8937092	22	22	HGNC:12716	Aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands	Gruenenthal GmbH	06/08/15	2D 3D TSV
US8940736	142	71	HGNC:2459 HGNC:2457	Imidazotriazinecarbonitriles useful as kinase inhibitors	Bristol-Myers Squibb Co.	06/08/15	2D 3D TSV
US8940719	16	16		Lithocholic acid analogues that inhibit sialyltransferase	Academia Sinica	06/08/15	2D 3D TSV
US8937084	27	15	HGNC:8153 HGNC:8154 HGNC:8156	Nitrogen containing morphinan derivatives and the use thereof	Purdue Pharma LP	06/08/15	2D 3D TSV
US8937068	220	51	HGNC:6871 HGNC:8975 HGNC:6886 HGNC:6876	Pyridopyrazine derivatives and their use	Zentaris GmbH	06/08/15	2D 3D TSV
US8940738	11	11		Pyrimidone compounds	Mitsubishi Tanabe Pharma Corporation	06/08/15	2D 3D TSV
US8933228	147	36	HGNC:4840 HGNC:11283 HGNC:6874 HGNC:6876	Respiratory formulations and compounds for use therein	Respivert Ltd	06/08/15	2D 3D TSV
US8933224	248	169	HGNC:8772	Triazine derivatives	Pfizer Inc	06/08/15	2D 3D TSV
US8927738	26	26	HGNC:8772	2-arylimidazole derivatives as PDE10A enzyme inhibitors	H. Lundbeck A/S	06/01/15	2D 3D TSV
US8933024	22	22	HGNC:6623	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases	Sanofi	06/01/15	2D 3D TSV
US8933098	4	1	HGNC:9594 HGNC:9593 HGNC:9596 HGNC:9595	Dimethyl-benzoic acid compounds	Eli Lilly and Company	06/01/15	2D 3D TSV
US8933221	31	29	HGNC:933	Hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	06/01/15	2D 3D TSV
US8927730	16	8		Intramolecular hydrogen-bonded nitric oxide synthase inhibitors	Northwestern University	06/01/15	2D 3D TSV
US8933095	29	29	HGNC:17929	KAT II inhibitors	Pfizer Inc	06/01/15	2D 3D TSV
US8927563	4	1	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6874	Kinase inhibitor	Respivert Limited	06/01/15	2D 3D TSV
US8933099	139	128	HGNC:3690 HGNC:3691 HGNC:3676 HGNC:3688	Monocyclic pyridine derivative	Eisai R&D Management Co., Ltd	06/01/15	2D 3D TSV
US8933079	121	119	HGNC:4479	Pyridone and pyridazinone derivatives as anti-obesity agents	Boehringer Ingelheim International GmbH	06/01/15	2D 3D TSV
US8927577	27	23	HGNC:4191	Quinolinyl glucagon receptor modulators	Pfizer Inc	06/01/15	2D 3D TSV
US8933040	7	7	HGNC:7056	Selective glycosidase inhibitors and uses thereof	TBA	06/01/15	2D 3D TSV
US8933056	55	27	HGNC:3009	Soft protease inhibitors and pro-soft forms thereof	Trustees of Tufts College	06/01/15	2D 3D TSV
US8921559	61	53	HGNC:1603	4-substituted-cyclohexylamino-4-piperidinyl-acetamide antagonists of CCR2	Janssen Pharmaceutica NV	05/26/15	2D 3D TSV
US8927520	6	3		Antibacterial compounds	Institut Curie	05/26/15	2D 3D TSV
US8921397	263	88	HGNC:3023 HGNC:3024	Benzofurane-piperidine compounds	Hoffmann-La Roche Inc	05/26/15	2D 3D TSV
US8921412	16	16	HGNC:11037	C-aryl ansa SGLT2 inhibitors	Green Cross Corporation	05/26/15	2D 3D TSV
US8927534	24	12	HGNC:6141 HGNC:6138	Compounds for the inhibition of integrins and use thereof	Shire Orphan Therapies GmbH	05/26/15	2D 3D TSV
US8927539	10	10	HGNC:5208	Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure	Vitae Pharmaceuticals Inc	05/26/15	2D 3D TSV
US8921424	13	13	HGNC:14064	Histone deacetylase inhibitors, process for preparation and uses thereof	Zhejiang Hisun Pharmaceutical Co., Ltd	05/26/15	2D 3D TSV
US8921421	2	2	HGNC:2715	Inhibitors of dimethylarginine dimethylaminohydrolase	Christian-Albrechts-Universitaet Zu Kiel	05/26/15	2D 3D TSV
US8921389	217	217	HGNC:1232	Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase	FibroGen Inc	05/26/15	2D 3D TSV
US8921410	175	79	HGNC:1958	Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes	Targacept Inc	05/26/15	2D 3D TSV
US8927507	8	8	HGNC:7056	Selective glycosidase inhibitors and uses thereof	TBA	05/26/15	2D 3D TSV
US8927536	14	14	HGNC:5208	Tetrahydrothiazepine derivative	Daiichi Sankyo Company, Limited	05/26/15	2D 3D TSV
US8653304	10	9	HGNC:6876	2,3-dihydro-1H-indene-2-yl urea derivative and pharmaceutical application of same	Toray Industries Inc	05/18/15	2D 3D TSV
US8916594	27	25	HGNC:7958	5-membered ring heteroaromatic derivatives having NPY Y5 receptor antagonistic activity	Shionogi & Co., Ltd	05/18/15	2D 3D TSV
US8921404	9	9		Azole derivatives in the form of lipase and phospholipase inhibitors	Sanofi	05/18/15	2D 3D TSV
US8921370	20	10	HGNC:4597	Bicyclo[3.2.1]octyl amide derivatives and uses of same	H. Lundbeck A/S	05/18/15	2D 3D TSV
US8921373	25	22	HGNC:12716	Compounds having TRPV1 antagonistic activity and uses thereof	Shionogi & Co., Ltd	05/18/15	2D 3D TSV
US8653257	5	5	HGNC:3023	Dibenzothiazepine derivatives and uses thereof—424	AstraZeneca AB	05/18/15	2D 3D TSV
US8921364	56	56	HGNC:28657	Modulators of calcium release-activated calcium channel	Rhizen Pharmaceuticals SA	05/18/15	2D 3D TSV
US8916600	20	17	HGNC:7978	Phenyl and benzodioxinyl substituted indazoles derivatives	AstraZeneca AB	05/18/15	2D 3D TSV
US8921368	103	53	HGNC:6190 HGNC:6193	Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases	Bristol-Myers Squibb Co.	05/18/15	2D 3D TSV
US8921319	60	15	HGNC:6371 HGNC:3528 HGNC:3535 HGNC:9071	Serine protease inhibitors	The Medicines Company (Leipzig) GmbH	05/18/15	2D 3D TSV
US8653100	267	180	HGNC:11056	Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy	AbbVie Inc	05/18/15	2D 3D TSV
US8916577	22	16	HGNC:12401 HGNC:8987	Tricyclic derivatives, process for their preparation and their use as kinase inhibitors	Nerviano Medical Sciences srl	05/18/15	2D 3D TSV
US8912208	4	4	HGNC:2843	(4-{4-[5-(benzooxazol-2-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid useful for treating or preventing conditions or disorders associated with DGAT1 activity	Novartis AG	05/11/15	2D 3D TSV
US8916574	6	6	HGNC:3236	4-(substituted anilino)-quinazoline derivatives useful as tyrosine kinase inhibitors	Qilu Pharmaceutical Co., Ltd	05/11/15	2D 3D TSV
US8912219	10	10		Aryl sulfamide and sulfamate derivatives as RORc modulators	Genentech Inc	05/11/15	2D 3D TSV
US8912221	44	44	HGNC:1029	Biaryl amide derivatives	Hoffmann-La Roche Inc	05/11/15	2D 3D TSV
US8912181	115	115	HGNC:5253	Bicyclic compound or salt thereof	Taiho Pharmaceutical Co., Ltd	05/11/15	2D 3D TSV
US8907086	8	8	HGNC:3009	Fused bicyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors	Merck Sharp & Dohme Corp	05/11/15	2D 3D TSV
US8916576	100	51	HGNC:10251 HGNC:10252	Pharmacokinetically improved compounds	Surface Logix, Inc.	05/11/15	2D 3D TSV
US8912224	390	360	HGNC:11068	Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals	Sanofi	05/11/15	2D 3D TSV
US8912173	121	119	HGNC:11491	Substituted quinolines and their use as medicaments	Boehringer Ingelheim International GmbH	05/11/15	2D 3D TSV
US8916553	45	45	HGNC:2593	Sulfonamide compounds useful as CYP17 inhibitors	Bristol-Myers Squibb Co.	05/11/15	2D 3D TSV
US8912213	12	12	HGNC:18884	Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (TDP1)- topoisomerase I (TOP1) inhibitors	Purdue Research Foundation	05/11/15	2D 3D TSV
US8906943	19	10	HGNC:2615 HGNC:2610	Synthetic compounds and methods to decrease nicotine self-administration	TBA	05/11/15	2D 3D TSV
US8895581	96	94	HGNC:8816	1H-imidazo[4,5-c]quinolines	Boehringer Ingelheim International GmbH	05/04/15	2D 3D TSV
US8901140	7	7	HGNC:3236	6-amino quinazoline or 3-cyano quinoline derivatives, preparation methods and pharmaceutical uses thereof	Jiangsu Hengrui Medicine Co., Ltd.	05/04/15	2D 3D TSV
US8895745	17	17	HGNC:3690	Bicyclic heterocyclic compounds as FGFR inhibitors	Astex Therapeutics Limited	05/04/15	2D 3D TSV
US8906911	68	68	HGNC:1603	Chemokine receptor antagonists	AbbVie Inc	05/04/15	2D 3D TSV
US8895592	76	38	HGNC:2160	Compounds as cannabinoid receptor ligands	AbbVie Inc	05/04/15	2D 3D TSV
US8901115	25	24	HGNC:3529	Cyclic P1 linkers as factor XIa inhibitors	Bristol-Myers Squibb Co.	05/04/15	2D 3D TSV
US8906933	30	20	HGNC:11528 HGNC:253	Dihydropyrimidin-2(1H)-one compounds as neurokinin-3 receptor antagonists	N30 Pharmaceuticals, Inc.	05/04/15	2D 3D TSV
US8901295	31	16	HGNC:9255 HGNC:9257 HGNC:14650	Inhibitors of cyclophilins and uses thereof	University of Montpellier	05/04/15	2D 3D TSV
US8901087	39	39	HGNC:7056	Selective glycosidase inhibitors and uses thereof	Merck Sharp & Dohme Corp	05/04/15	2D 3D TSV
US8901315	337	165	HGNC:8791	Thienopyrazole derivative having PDE7 inhibitory activity	Daiichi Sankyo Company, Limited	05/04/15	2D 3D TSV
US8901310	29	14	HGNC:7978 HGNC:195 HGNC:6018	Tricyclic compounds, compositions, and methods	Pfizer Inc	05/04/15	2D 3D TSV
US8614223	561	138	HGNC:4852 HGNC:14064 HGNC:4854 HGNC:4853	Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof	Acetylon Pharmaceuticals Inc	05/03/15	2D 3D TSV
US8895549	35	35	HGNC:8976	Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis	Bayer Intellectual Property GmbH	04/27/15	2D 3D TSV
US8889684	10	10		Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors	Boehringer Ingelheim International GmbH	04/27/15	2D 3D TSV
US8889671	80	77		Compounds and methods for treating bacterial infections	AstraZeneca AB	04/27/15	2D 3D TSV
US8889672	29	26	HGNC:9412	Compounds, formulations, and methods of protein kinase C inhibition	University of Michigan	04/27/15	2D 3D TSV
US8614195	22	11	HGNC:11037 HGNC:11036	Glycoside derivatives and uses thereof	Novartis AG	04/27/15	2D 3D TSV
US8895544	57	28	HGNC:6190 HGNC:6193	Indazoles	Pfizer Inc	04/27/15	2D 3D TSV
US8895245	10	2	HGNC:3527	Inhibitors of human EZH2 and methods of use thereof	Epizyme Inc	04/27/15	2D 3D TSV
US8889870	111	88	HGNC:6307 HGNC:8804	Kinase inhibitors	Allergan Inc	04/27/15	2D 3D TSV
US8894989	59	57	HGNC:270	PARP inhibitor compounds, compositions and methods of use	Eisai Inc.	04/27/15	2D 3D TSV
US8889708	42	30	HGNC:2528 HGNC:2536	Substituted bicyclic 1-carboxylic-acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	04/27/15	2D 3D TSV
US8889696	65	2	HGNC:6190 HGNC:6192 HGNC:19310 HGNC:9077 HGNC:11283 HGNC:14542 HGNC:10430 HGNC:19699 HGNC:2453 HGNC:11724 HGNC:6735 HGNC:6307 HGNC:1057 HGNC:12858 HGNC:76 HGNC:3690 HGNC:6342 HGNC:1777 HGNC:9412 HGNC:7744 HGNC:6524 HGNC:3688 HGNC:3765	Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof	Temple University	04/27/15	2D 3D TSV
US8889724	7	7	HGNC:17989	Tetrazole compounds for reducing uric acid	Wellstat Therapeutics Corporation	04/27/15	2D 3D TSV
US8877733	2	2		1′-substituted pyrimidine N-nucleoside analogs for antiviral treatment	Gilead Sciences Inc	04/20/15	2D 3D TSV
US8884017	21	21	HGNC:1960	2-heteroarylcarboxylic acid amides	Bayer Intellectual Property GmbH	04/20/15	2D 3D TSV
US8883759	20	20	HGNC:3078	Anti-tumor effect potentiator	Taiho Pharmaceutical Co., Ltd	04/20/15	2D 3D TSV
US8883784	15	15	HGNC:992	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases	AbbVie Inc	04/20/15	2D 3D TSV
US8883771	150	50	HGNC:590 HGNC:591 HGNC:592	Bivalent inhibitors of IAP proteins and therapeutic methods using the same	The Regents of the University of Michigan	04/20/15	2D 3D TSV
US8614213	83	82	HGNC:2357	Cyclohexyl amide derivatives and their use as CRF-1 receptor antagonists	Novartis AG	04/20/15	2D 3D TSV
US8883797	12	4	HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals Inc	04/20/15	2D 3D TSV
US8889668	31	31	HGNC:3165	Oxadiazole diaryl compounds	Merck Serono	04/20/15	2D 3D TSV
US8877741	485	478	HGNC:85	Pyrrolidine derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	04/20/15	2D 3D TSV
US8614220	15	15	HGNC:9077	Substituted pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors	Nerviano Medical Sciences srl	04/20/15	2D 3D TSV
US8883846	5	4		Synthesis of bicyclic compounds and method for their use as therapeutic agents	UVic Industry Partnerships Inc.	04/20/15	2D 3D TSV
US8877798	71	26		1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders	Neurovance, Inc.	04/13/15	2D 3D TSV
US8877944	96	53		3-oxo-2,3-dihydro-1H-isoindole-4-carboxamides as PARP inhibitors	Nerviano Medical Sciences srl	04/13/15	2D 3D TSV
US8877778	285	95	HGNC:3023 HGNC:3024	Benzofurane compounds	Hoffmann-La Roche Inc	04/13/15	2D 3D TSV
US8877967	42	13	HGNC:2527 HGNC:2536 HGNC:2537	Compositions and methods for inhibition of cathepsins	OXiGENE, Inc.	04/13/15	2D 3D TSV
US8871738	76	74	HGNC:1869	Fused bicyclic oxazolidinone CETP inhibitor	Merck Sharp & Dohme Corp	04/13/15	2D 3D TSV
US8877795	33	33	HGNC:12405	Identification of stabilizers of multimeric proteins	The Board of Trustees of the Leland Stanford Junior University	04/13/15	2D 3D TSV
US8877791	8	8	HGNC:9021	Inhibitors of pyruvate kinase and methods of treating disease	Beth Israel Deaconess Medical Center, Inc.	04/13/15	2D 3D TSV
US8871728	49	28	HGNC:14064 HGNC:13315	Non-peptide macrocyclic histone deacetylese (HDAC) inhibitors and methods of making and using thereof	Georgia Tech Research Corporation	04/13/15	2D 3D TSV
US8877757	7	7	HGNC:8977	Pyrazine derivatives and use as PI3K inhibitors	Merck Serono	04/13/15	2D 3D TSV
US8877775	37	25	HGNC:2528 HGNC:2536	Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	04/13/15	2D 3D TSV
US8877786	7	7	HGNC:7154	Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors	Novartis AG	04/13/15	2D 3D TSV
US8871778	44	22	HGNC:6307 HGNC:11491	Substituted pyrimidine compounds and their use as SYK inhibitors	Genosco	04/13/15	2D 3D TSV
US8865911	180	153	HGNC:933	Compounds and their use as BACE inhibitors	AstraZeneca AB	04/06/15	2D 3D TSV
US8865655	4	4	HGNC:4852	Depsipeptides and their therapeutic use	Karus Therapeutics Limited	04/06/15	2D 3D TSV
US8871934	680	653	HGNC:8810	Fluorene compound and pharmaceutical use thereof	Japan Tobacco Inc	04/06/15	2D 3D TSV
US8865706	30	30	HGNC:933	Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds	Pfizer Inc	04/06/15	2D 3D TSV
US8871790	475	472	HGNC:3594	Heterocyclic modulators of lipid synthesis	3-V Biosciences, Inc.	04/06/15	2D 3D TSV
US8865662	5	5	HGNC:8780	Macrolides and their use	Basilea Pharmaceutica AG	04/06/15	2D 3D TSV
US8865698	105	105	HGNC:8031	Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds	Array BioPharma Inc	04/06/15	2D 3D TSV
US8865714	35	35	HGNC:17890	Piperazine compound capable of inhibiting prostaglandin D synthase	Taiho Pharmaceutical Co., Ltd	04/06/15	2D 3D TSV
US8865701	11	11	HGNC:933	Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer'S disease	Merck Sharp & Dohme Corp	04/06/15	2D 3D TSV
US8871783	26	26	HGNC:2528	Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides inhibitors of cathepsin C	Boehringer Ingelheim International GmbH	04/06/15	2D 3D TSV
US8865726	144	143	HGNC:3942	Substituted pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors	Array BioPharma Inc	04/06/15	2D 3D TSV
US8865686	8	8	HGNC:18884	Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors	The United States of America, as Represented by the Secretary, Dept. of Health and Human Services	04/06/15	2D 3D TSV
US8859534	106	53		2-carboxamide-7-piperazinyl-benzofuran derivatives	Acturum Life Science AB	03/16/15	2D 3D TSV
US8853224	62	31	HGNC:7892	Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases	Industrial Research Limited	03/16/15	2D 3D TSV
US8859596	128	64	HGNC:2160	Compounds as cannabinoid receptor ligands	AbbVie Inc	03/16/15	2D 3D TSV
US8859586	50	32	HGNC:6973 HGNC:6974	Cyclohexyl isoquinolinone compounds	Novartis AG	03/16/15	2D 3D TSV
US8853215	17	17	HGNC:9922	Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes	Takeda Pharmaceutical Co., Ltd	03/16/15	2D 3D TSV
US8853203	366	185	HGNC:4597 HGNC:4593	Diazepinone derivatives	Novartis AG	03/16/15	2D 3D TSV
US8853227	9	9	HGNC:12576	Methotrexate adjuvants to reduce toxicity and methods for using the same	Tosk, Incorporated	03/16/15	2D 3D TSV
US8865750	10	4	HGNC:13735 HGNC:16810 HGNC:10000 HGNC:9997	Small molecule inhibitors of RGS proteins	University of Michigan	03/16/15	2D 3D TSV
US8853212	17	16	HGNC:3009	Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes	Merck Sharp & Dohme Corp	03/16/15	2D 3D TSV
US8853193	170	165	HGNC:7111	Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions	Boehringer Ingelheim International GmbH	03/16/15	2D 3D TSV
US8853206	11	11	HGNC:3537	Triazolium salts as PAR1 inhibitors, production thereof, and use as medicaments	Sanofi	03/16/15	2D 3D TSV
US8853226	26	13	HGNC:8781 HGNC:8783	Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors	High Point Pharmaceuticals, LLC	03/16/15	2D 3D TSV
US8853258	197	197		C-linked hydroxamic acid derivatives useful as antibacterial agents	Pfizer Inc	03/09/15	2D 3D TSV
US8853228	67	26	HGNC:2861	Heterocyclic analogs of propargyl-linked inhibitors of dihydrofolate reductase	University of Connecticut	03/09/15	2D 3D TSV
US8853207	12	6	HGNC:8804 HGNC:6342	Heterocyclic pyrazole compounds, method for preparing the same and use thereof	Development Center for Biotechnology	03/09/15	2D 3D TSV
US8846601	142	126	HGNC:6932 HGNC:6929	Melanocortin receptor-specific peptides	Palatin Technologies Inc	03/09/15	2D 3D TSV
US8853242	18	18	HGNC:5300	Nitrogenous-ring acylguanidine derivative	Astellas Pharma Inc	03/09/15	2D 3D TSV
US8846658	184	180	HGNC:933	Oxazine derivatives and their use in the treatment of neurological disorders	Novartis AG	03/09/15	2D 3D TSV
US8846698	511	506	HGNC:8031	Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors	Pfizer Inc	03/09/15	2D 3D TSV
US8846000	35	35	HGNC:8772	Radiolabeled PDE10 inhibitors	Merck Sharp & Dohme Corp	03/09/15	2D 3D TSV
US8846657	356	282	HGNC:6973	Substituted imidazopyridines as HDM2 inhibitors	Merck Sharp & Dohme Corp	03/09/15	2D 3D TSV
US8846656	146	143	HGNC:1338	Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators	Novartis AG	03/09/15	2D 3D TSV
US8846654	11	8	HGNC:8791 HGNC:8793	Therapeutic applications in the cardiovascular field of quinazolinedione derivatives	Sanofi	03/09/15	2D 3D TSV
US8846673	38	38	HGNC:1133	Azaindazoles as kinase inhibitors and use thereof	Bristol-Myers Squibb Co.	03/03/15	2D 3D TSV
US8846730	132	65	HGNC:2160	Compounds as cannabinoid receptor ligands	AbbVie Inc	03/03/15	2D 3D TSV
US8846711	28	28		Heterocyclic acrylamides and their use as pharmaceuticals	Fab Pharma S.A.S.	03/03/15	2D 3D TSV
US8846719	372	371	HGNC:4079	Isoxazolo-pyridine derivatives	Roche Palo Alto LLC	03/03/15	2D 3D TSV
US8846741	9	8	HGNC:11056	N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy	AbbVie Inc	03/03/15	2D 3D TSV
US8846696	60	10	HGNC:9380 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:6871 HGNC:1773	Purine derivatives	Cyclacel Limited	03/03/15	2D 3D TSV
US8846746	520	511	HGNC:11036	Pyrazole compound and pharmaceutical use thereof	Japan Tobacco Inc	03/03/15	2D 3D TSV
US8846699	346	170	HGNC:6307 HGNC:3236	Quinazoline derivatives as a multiplex inhibitor and method for the preparation thereof	Hanmi Pharm. Co., Ltd	03/03/15	2D 3D TSV
US8846660	29	29	HGNC:2097	Seven-membered ring compound and pharmaceutical use therefor	Daiichi Sankyo Company, Ltd.	03/03/15	2D 3D TSV
US8846689	212	211	HGNC:9611	Substituted pyrimidines for the treatment of diseases such as cancer	Boehringer Ingelheim International GmbH	03/03/15	2D 3D TSV
US8846929	836	251	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Substituted-quinoxaline-type piperidine compounds and the uses thereof	Purdue Pharma LP	03/03/15	2D 3D TSV
US8835436	169	60	HGNC:11050 HGNC:5295	Arylpiperazine-containing imidazole 4-carboxamide derivatives and pharmaceutical composition comprising same	Green Cross Corporation	02/23/15	2D 3D TSV
US8841450	2	2	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Inc	02/23/15	2D 3D TSV
US8846917	1	1	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Inc	02/23/15	2D 3D TSV
US8835444	36	28	HGNC:2358 HGNC:2357	Cyclohexyl amide derivatives as CRF receptor antagonists	Novartis AG	02/23/15	2D 3D TSV
US8835445	82	40	HGNC:2861	Dihydrofolate reductase inhibitors	Trius Therapeutics Inc	02/23/15	2D 3D TSV
US8841312	749	480	HGNC:1777 HGNC:1773	Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors	Amgen Inc	02/23/15	2D 3D TSV
US8841453	36	18	HGNC:108 HGNC:983	Hybrid cholinesterase inhibitors	Uniwersytet Warszawski	02/23/15	2D 3D TSV
USRE45173	173	146	HGNC:2593	Inhibitors of CYP 17	Novartis AG	02/23/15	2D 3D TSV
US8841288	10	10	HGNC:8975	Quinolin-4 (1H)-one derivatives as inhibitors of phosphatidylinositol 3-kinases	Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”	02/23/15	2D 3D TSV
US8841455	165	165		Substituted N-(1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide compounds as cFMS inhibitors	Array BioPharma Inc	02/23/15	2D 3D TSV
US8835464	53	50	HGNC:5258	Triazole compounds that modulate HSP90 activity	Synta Pharmaceuticals Corp.	02/23/15	2D 3D TSV
US8835472	664	663	HGNC:85	Compounds, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	02/16/15	2D 3D TSV
US8828983	13	12	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Co.	02/16/15	2D 3D TSV
US8835470	25	25	HGNC:3165	Mandelamide heterocyclic compounds	Bristol-Myers Squibb Co.	02/16/15	2D 3D TSV
US8829193	162	54	HGNC:19310 HGNC:8987	PIM kinase inhibitors and methods of their use	Novartis AG	02/16/15	2D 3D TSV
US8835659	7	7	HGNC:14929	Polysubstituted benzofurans and medicinal applications thereof	Ikerchem, S.L.	02/16/15	2D 3D TSV
US8829010	57	55		Pyrazolo[3,4-d]pyrimidine compounds and their use as PDE2 inhibitors and/or CYP3A4 inhibitors	Pfizer Inc	02/16/15	2D 3D TSV
US8835465	3	3	HGNC:8031	Pyrazolylaminopyridine derivatives useful as kinase inhibitors	AstraZeneca AB	02/16/15	2D 3D TSV
US8829009	6	6	HGNC:5301	Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof	TBA	02/16/15	2D 3D TSV
US8829000	22	11	HGNC:8784 HGNC:8795	Substituted imidazo[1,5-A]quinoxalines as phosphodiesterase 9 inhibitors	ASKA Pharmaceutical Co., Ltd	02/16/15	2D 3D TSV
US8829190	28	28	HGNC:8780	Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases	Leo Pharma A/S	02/16/15	2D 3D TSV
US8822479	7	7	HGNC:8795	6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines	Boehringer Ingelheim International GmbH	02/02/15	2D 3D TSV
US8829199	333	111	HGNC:3690 HGNC:3689 HGNC:3688	Aminopyrazole derivative	Chugai Seiyaku Kabushiki Kaisha	02/02/15	2D 3D TSV
US8822505	100	40	HGNC:2537 HGNC:2545	Azetidine derivatives	Genentech Inc	02/02/15	2D 3D TSV
US8829200	30	30	HGNC:436	Benzimidazole inhibitors of leukotriene production	Boehringer Ingelheim International GmbH	02/02/15	2D 3D TSV
US8822460	15	10	HGNC:1603	Fused cyclopentyl antagonists of CCR2	Janssen Pharmaceutica NV	02/02/15	2D 3D TSV
US8822494	47	42	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	02/02/15	2D 3D TSV
US8822447	155	154		Indazole compounds useful as ketohexokinase inhibitors	Janssen Pharmaceutica NV	02/02/15	2D 3D TSV
US8822457	4	4	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Roche Palo Alto LLC	02/02/15	2D 3D TSV
US8822448	100	100		Pyrazoloquinoline compound	Astellas Pharma Inc	02/02/15	2D 3D TSV
US8822510	15	15	HGNC:3165	Substituted 3-phenyl-1,2,4-Oxadiazole compounds	Bristol-Myers Squibb Co.	02/02/15	2D 3D TSV
US8822458	61	60	HGNC:3528	Substituted oxazolidinones and their use in the field of blood coagulation	Bayer Intellectual Property GmbH	02/02/15	2D 3D TSV
US8822500	55	14	HGNC:6091 HGNC:5465 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:10261 HGNC:175 HGNC:7029 HGNC:9967	Tyrosine kinase inhibitors	ChemBridge Corporation	02/02/15	2D 3D TSV
US8815881	20	20	HGNC:934	1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds	Hoffmann-La Roche Inc	01/26/15	2D 3D TSV
US8815845	10	5	HGNC:10251 HGNC:10252	1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties	The Regents of the University of Michigan	01/26/15	2D 3D TSV
US8815927	11	6	HGNC:591	Bivalent diazo bicyclic Smac mimetics and the uses thereof	The Regents of the University of Michigan	01/26/15	2D 3D TSV
US8815852	34	17		Carbamoyloxy arylalkan arylpiperazine analgesics	SK Biopharmaceuticals Co. Ltd	01/26/15	2D 3D TSV
US8815840	94	94	HGNC:6192	Carbazole and carboline kinase inhibitors	Bristol-Myers Squibb Co.	01/26/15	2D 3D TSV
US8815918	14	14	HGNC:8975	Imidazo [2, 1-B] [1, 3, 4] thiadiazole derivatives	Centro Nacional de Investigaciones Oncologicas (CNIO)	01/26/15	2D 3D TSV
US8815901	52	51	HGNC:3690	Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors	Novartis AG	01/26/15	2D 3D TSV
US8822534	22	20	HGNC:14668	Substituted aminopropionic derivatives as neprilysin inhibitors	Novartis AG	01/26/15	2D 3D TSV
US8815854	24	24	HGNC:391	Substituted imidazopyridinyl compounds	ArQule Inc	01/26/15	2D 3D TSV
US8815926	334	310	HGNC:6973 HGNC:6974	Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases	Novartis AG	01/26/15	2D 3D TSV
US8815891	114	112	HGNC:270	Tricyclic derivative or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition containing the same	Jeil Pharmaceutical Co., Ltd	01/26/15	2D 3D TSV
US8815934	54	53	HGNC:3467	2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations	Wyeth LLC	01/19/15	2D 3D TSV
US8802674	212	207	HGNC:18618	Aminopyrimidine derivatives as LRRK2 modulators	Genentech Inc	01/19/15	2D 3D TSV
US8816088	96	94	HGNC:1952	Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity	Theravance Respiratory Company LLC	01/19/15	2D 3D TSV
US8802679	44	22	HGNC:550	Glycine compound	Astellas Pharma Inc	01/19/15	2D 3D TSV
US8802673	421	210		Heterocyclic amine derivatives	Hoffmann-La Roche Inc	01/19/15	2D 3D TSV
US8815951	300	150	HGNC:3401	Inhibitors of epoxide hydrolases for the treatment of inflammation	The Regents of the University of California	01/19/15	2D 3D TSV
US8802663	45	42	HGNC:3165	Pyrazole oxadiazole derivatives as S1P1 agonists	Merck Serono	01/19/15	2D 3D TSV
US8802712	80	80	HGNC:9413	Pyrazoloquinolines	Merck Patent GmbH	01/19/15	2D 3D TSV
US8802672	27	9		Pyrimidinyl-piperazines useful as D3/D2 receptor ligands	Richter Gedeon Nyrt.	01/19/15	2D 3D TSV
US8802665	48	48	HGNC:2545	Pyrrolidine derivatives	Genentech Inc	01/19/15	2D 3D TSV
US8802686	63	16	HGNC:6307 HGNC:1771 HGNC:1722 HGNC:1773	Sulfone-substituted anilinopyrimidine derivatives as CDK inhibitors, the production thereof, and use as a medicine	Bayer Intellectual Property GmbH	01/19/15	2D 3D TSV
US8802711	155	155	HGNC:12716	TRPV1 antagonists	AbbVie Inc	01/19/15	2D 3D TSV
US8796280	46	46	HGNC:4502	2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors	Merck Serono	01/12/15	2D 3D TSV
US8796284	21	17	HGNC:263	4-aminopyrimidine derivatives and their as as adenosine A2a receptor antagonists	Palobiofarma, S.L.	01/12/15	2D 3D TSV
US8796296	33	32	HGNC:18618	Aminopyrimidine derivatives as LRRK2 modulators	Genentech Inc	01/12/15	2D 3D TSV
US8802695	41	24	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors	Takeda Pharmaceutical Co., Ltd	01/12/15	2D 3D TSV
US8796244	586	312	HGNC:6307 HGNC:3690	Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases	Astex Therapeutics Ltd	01/12/15	2D 3D TSV
US8802724	5	3		Processes and intermediates for preparing substituted hexahydrofuro [2,3-b] furans	Purdue Research Foundation	01/12/15	2D 3D TSV
US8796293	9	9	HGNC:10252	Purine and deazapurine derivatives as pharmaceutical compounds	The Institute of Cancer Research	01/12/15	2D 3D TSV
US8796295	30	15	HGNC:4597	Substituted benzamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same	Vanderbilt University	01/12/15	2D 3D TSV
US8802861	17	17	HGNC:8978	Thiazole derivatives and use thereof	Merck Serono	01/12/15	2D 3D TSV
US8802721	9	9	HGNC:6001	Thiophene compounds for inflammation and immune-related uses	Synta Pharmaceuticals Corp.	01/12/15	2D 3D TSV
US8802864	12	12	HGNC:3594	Triazolones as fatty acid synthase inhibitors	GlaxoSmithKline	01/12/15	2D 3D TSV
US8796297	46	23	HGNC:5184	4-substituted-2-amino-pyrimidine derivatives	AbbVie Inc	12/22/14	2D 3D TSV
US8796310	83	79	HGNC:11491	Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors	Merck Sharp & Dohme Corp	12/22/14	2D 3D TSV
US8791130	46	46	HGNC:18618	Aminopyrimidine derivatives as LRRK2 modulators	Genentech Inc	12/22/14	2D 3D TSV
US8791100	79	77	HGNC:3165	Aryl benzylamine compounds	Novartis AG	12/22/14	2D 3D TSV
US8796457	1	1	HGNC:6190	Compound useful for the treatment of degenerative and inflammatory diseases	Galapagos NV	12/22/14	2D 3D TSV
US8796330	80	74	HGNC:4852 HGNC:13315	Inhibitors of histone deacetylase and prodrugs thereof	MethylGene Inc	12/22/14	2D 3D TSV
US8791118	38	38	HGNC:6871	Pyridopyrazines as highly selective ras-Raf-Mek-Erk signal transduction pathway inhibitors	Aeterna Zentaris GmbH	12/22/14	2D 3D TSV
US8791123	504	233	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:12440	Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharma Inc	12/22/14	2D 3D TSV
US8796328	44	44	HGNC:12716	TRPV1 antagonists	TBA	12/22/14	2D 3D TSV
US8796304	19	18	HGNC:8772	Tricyclic imidazole compounds as PDE10 inhibitors	H. Lundbeck A/S	12/22/14	2D 3D TSV
US8785467	20	20	HGNC:8772	Alkoxy pyrimidine PDE10 inhibitors	Merck Sharp & Dohme Corp	12/16/14	2D 3D TSV
US8785489	97	97		Heteroaryl substituted indole compounds useful as MMP-13 inhibitors	Boehringer Ingelheim International GmbH	12/16/14	2D 3D TSV
US8785477	9	9		Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof	Shanghai Sun-Sail Pharmaceutical Science & Technology Co., Ltd.	12/16/14	2D 3D TSV
US8791131	292	152	HGNC:8975 HGNC:3942	Imidazo[1,5]naphthyridine compounds, their pharmaceutical use and compositions	Pfizer Inc	12/16/14	2D 3D TSV
US8791272	215	214	HGNC:4502	Pyrazole compounds as CRTH2 antagonists	Boehringer Ingelheim International GmbH	12/16/14	2D 3D TSV
US8785464	81	80	HGNC:9611	Pyrimidine derivatives that inhibit FAK/PTK2	Boehringer Ingelheim International GmbH	12/16/14	2D 3D TSV
US8785459	386	128	HGNC:9829 HGNC:1097	Quinazoline compounds as kinase inhibitors	Development Center for Biotechnology	12/16/14	2D 3D TSV
US8791257	60	30	HGNC:2459 HGNC:2457	Substituted pyrrolotriazines as protein kinase inhibitors	Bristol-Myers Squibb Co.	12/16/14	2D 3D TSV
US8791268	22	15	HGNC:12716	Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions	Gruenenthal GmbH	12/16/14	2D 3D TSV
US8778932	5	5	HGNC:4079	Dihydro-oxazolobenzodiazepinone compounds, a process for there preparation and pharmaceutical compositions containing them	Les Laboratoires Servier	12/15/14	2D 3D TSV
US8785634	9	9	HGNC:9344	Spiropiperidine prolylcarboxypeptidase inhibitors	Merck Sharp & Dohme Corp	12/15/14	2D 3D TSV
US8785499	8	8		Targeting NAD biosynthesis in bacterial pathogens	University of Maryland, Baltimore	12/15/14	2D 3D TSV
US8779142	157	157	HGNC:5253	Azabicyclo compound and salt thereof	Taiho Pharmaceutical Co., Ltd	12/08/14	2D 3D TSV
US8772304	33	33	HGNC:436	Benzimidazole inhibitors of leukotriene production	Boehringer Ingelheim International GmbH	12/08/14	2D 3D TSV
US8772285	2	2	HGNC:5184	Benzothiazoles having histamine H3 receptor activity	High Point Pharmaceuticals, LLC	12/08/14	2D 3D TSV
US8778970	55	18	HGNC:5286 HGNC:11050 HGNC:2625	Benzyl piperidine compound	Dainippon Sumitomo Pharma Co., Ltd	12/08/14	2D 3D TSV
US8778957	21	20		CGRP receptor antagonists	Merck Sharp & Dohme Corp	12/08/14	2D 3D TSV
US8778951	352	350	HGNC:1599	Heteroaryl compounds and their uses	Novartis AG	12/08/14	2D 3D TSV
US8772283	128	64	HGNC:391 HGNC:392	Imidazo-oxazine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	12/08/14	2D 3D TSV
US8778412	32	16	HGNC:1232 HGNC:12680	Methods for increasing the stabilization of hypoxia inducible factor-1 alpha	Aerpio Therapeutics Inc	12/08/14	2D 3D TSV
US8772288	36	36	HGNC:6876	Substituted spiro[cycloalkyl-1,3′-indo]-2′(1′H)-one derivatives and their use as P38 mitogen-activated kinase inhibitors	Almirall, S.A.	12/08/14	2D 3D TSV
US8772297	20	20		TGF-β signal transduction inhibitor	Kyoto University	12/08/14	2D 3D TSV
US8772282	6	6	HGNC:933	Tetrahydropyrrolothiazine compounds	Eli Lilly and Company	12/08/14	2D 3D TSV
US8785638	71	70		Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors	Katholieke Universiteit Leuven	12/08/14	2D 3D TSV
US8772495	1	1	HGNC:436	5-lipoxygenase-activating protein inhibitor	Panmira Pharmaceuticals, LLC	11/24/14	2D 3D TSV
US8765733	21	21	HGNC:12716	Amine substituted methanesulfonamide derivatives as vanilloid receptor ligands	Gruenenthal GmbH	11/24/14	2D 3D TSV
US8772481	21	21	HGNC:6876	Aza- and diaza-phthalazine compounds as P38 map kinase modulators and methods of use thereof	Amgen Inc	11/24/14	2D 3D TSV
US8772511	7	7		Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists	Bayer Intellectual Property GmbH	11/24/14	2D 3D TSV
US8765744	129	128	HGNC:5208	Azaspirohexanones	Boehringer Ingelheim International GmbH	11/24/14	2D 3D TSV
US8772478	21	9	HGNC:7173 HGNC:216 HGNC:7176 HGNC:7155 HGNC:188 HGNC:15478	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics	Galderma Research & Development	11/24/14	2D 3D TSV
US8772480	690	343	HGNC:8975 HGNC:3942	Inhibitors of PI3 kinase and/or mTOR	Amgen Inc	11/24/14	2D 3D TSV
US8772508	17	17	HGNC:25952	Inhibitors of glutaminyl cyclase	Probiodrug AG	11/24/14	2D 3D TSV
US8765727	95	19	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:427 HGNC:12440	Macrocyclic compounds and their use as kinase inhibitors	Incyte Corporation	11/24/14	2D 3D TSV
US8772510	65	65	HGNC:8772	PDE10 modulators	Hoffmann-La Roche Inc	11/24/14	2D 3D TSV
US8772316	84	84	HGNC:8772	Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE10A)	Allergan Inc	11/24/14	2D 3D TSV
US8772305	292	292	HGNC:11491	Substituted pyridinyl-pyrimidines and their use as medicaments	Boehringer Ingelheim International GmbH	11/24/14	2D 3D TSV
US8765972	19	19	HGNC:270	3-oxo-2,3-dihydro-1H-isoindole-4-carboxamides with selective PARP-1 inhibition	Nerviano Medical Sciences srl	11/18/14	2D 3D TSV
US8759537	85	85	HGNC:9599	3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents	Boehringer Ingelheim International GmbH	11/18/14	2D 3D TSV
US8759366	48	46	HGNC:11491	Aminopyrimidines as SYK inhibitors	Merck Sharp & Dohme Corp	11/18/14	2D 3D TSV
US8759341	15	11	HGNC:7029	Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof	Bayer Intellectual Property GmbH	11/18/14	2D 3D TSV
US8765747	21	1	HGNC:19006 HGNC:11388 HGNC:8803 HGNC:3763 HGNC:11724 HGNC:6307 HGNC:1772 HGNC:1771 HGNC:1097 HGNC:76 HGNC:1778 HGNC:6342 HGNC:1774 HGNC:3767 HGNC:6874 HGNC:2730 HGNC:9967 HGNC:3765	Fused 2-aminothiazole compounds	Dana-Farber Cancer Institute Inc	11/18/14	2D 3D TSV
US8765940	162	162	HGNC:8975	Heterocyclic compounds and their uses	Amgen Inc	11/18/14	2D 3D TSV
US8759338	57	19	HGNC:19310 HGNC:8987	Heterocyclic kinase inhibitors	Novartis AG	11/18/14	2D 3D TSV
US8759365	23	22	HGNC:1869	Organic compounds	Novartis AG	11/18/14	2D 3D TSV
US8765750	27	27	HGNC:17890	Piperazine compound having a PGDS inhibitory effect	Taiho Pharmaceutical Co., Ltd	11/18/14	2D 3D TSV
US8759386	59	59	HGNC:4502	Pyrazole compounds as CRTH2 antagonists	Boehringer Ingelheim International GmbH	11/18/14	2D 3D TSV
US8759532	266	253	HGNC:8772	Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors	Amgen Inc	11/18/14	2D 3D TSV
US8765820	21	8	HGNC:6833 HGNC:6834 HGNC:29079	Tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and/or LSD2	Sapienza University of Rome	11/18/14	2D 3D TSV
US8754075	87	52	HGNC:934 HGNC:933	1,3-oxazines as BACE1 and/or BACE2 inhibitors	Hoffmann-La Roche Inc	11/11/14	2D 3D TSV
US8748418	53	26	HGNC:934 HGNC:933	1,4-oxazepines as BACE1 and/or BACE2 inhibitors	Hoffmann-La Roche Inc	11/11/14	2D 3D TSV
US8748608	39	29	HGNC:3023 HGNC:3024	4-phenylpiperazine derivatives with functionalized linkers as dopamine D3 receptor selective ligands and methods of use	The United States of America as Represented by the Secretary of the Department of Health and Human Services	11/11/14	2D 3D TSV
US8748451	35	12	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	HDAC inhibitors and therapeutic methods of using same	University of Illinois	11/11/14	2D 3D TSV
US8754089	32	32	HGNC:8977	Heterocyclic compounds and their uses	Amgen Inc	11/11/14	2D 3D TSV
US8754106	9	8		Macrocyclic inhibitors of hepatitis C virus	Janssen Ireland	11/11/14	2D 3D TSV
US8754105	6	6		Macrocyclic inhibitors of hepatitis C virus	Medivir AB	11/11/14	2D 3D TSV
US8754227	15	5	HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals Inc	11/11/14	2D 3D TSV
US8754099	5	5	HGNC:11332	Oxadiazole beta carboline derivatives as antidiabetic compounds	Merck Sharp & Dohme Corp	11/11/14	2D 3D TSV
US8754113	39	39	HGNC:6623	Oxadiazole derivative having endothelial lipase inhibitory activity	Shionogi & Co., Ltd	11/11/14	2D 3D TSV
US8754233	151	151	HGNC:6040	Pyrazolylbenzothiazole derivatives and their use as therapeutic agents	Dermira (Canada), Inc.	11/11/14	2D 3D TSV
US8748458	41	10	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Scriptaid isosteres and their use in therapy	Karus Therapeutics Limited	11/11/14	2D 3D TSV
US8741907	16	7	HGNC:8793 HGNC:8781 HGNC:8792 HGNC:8784 HGNC:8795 HGNC:8772 HGNC:8776 HGNC:8779	Alkyl-substituted pyrazolopyrimidines	Boehringer Ingelheim International GmbH	11/05/14	2D 3D TSV
US8741944	37	37	HGNC:8816	Anti-infective agents against intracellular pathogens	The Ohio State University Research Foundation	11/05/14	2D 3D TSV
US8741915	24	23	HGNC:253	Dihydropyrimidin-2(1H)-one compounds as S-nitrosoglutathione reductase inhibitors	N30 Pharmaceuticals, Inc.	11/05/14	2D 3D TSV
US8742106	172	79	HGNC:4849 HGNC:4848	Disubstituted heteroaryl-fused pyridines	Novartis AG	11/05/14	2D 3D TSV
US8748618	36	34	HGNC:1539	Inhibitors of inv(16) leukemia	University of Virginia Patent Foundation	11/05/14	2D 3D TSV
US8741926	10	10		Macrocyclic inhibitors of hepatitis C virus	Janssen Ireland	11/05/14	2D 3D TSV
US8741923	19	19	HGNC:3165	Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis	Merck Serono	11/05/14	2D 3D TSV
US8748626	8	8	HGNC:6388	Oxazole and thiazole compounds as KSP inhibitors	Novartis AG	11/05/14	2D 3D TSV
US8748624	138	138	HGNC:4192	Picolinamido-propanoic acid derivatives useful as glucagon receptor antagonists	Janssen Pharmaceutica NV	11/05/14	2D 3D TSV
US8748435	37	37	HGNC:4497	Pyrazolo pyrimidine derivatives	Novartis AG	11/05/14	2D 3D TSV
US8742113	21	21	HGNC:1745	Furanone derivative	SBI Biotech Co., Ltd.	11/04/14	2D 3D TSV
US8742110	170	169	HGNC:11334	Spiroxazolidinone compounds	Merck Sharp & Dohme Corp	11/04/14	2D 3D TSV
US8729113	97	97		4,5-dihydro-oxazol-2yl derivatives	Hoffmann-La Roche Inc	10/28/14	2D 3D TSV
US8742134	8	4	HGNC:1952	7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof	Theron Pharmaceuticals, Inc.	10/28/14	2D 3D TSV
US8735386	429	422	HGNC:5465	Aminopyrazoloquinazolines	Boehringer Ingelheim International GmbH	10/28/14	2D 3D TSV
US8735593	10	5	HGNC:4617 HGNC:4616	Aminopyridines useful as inhibitors of protein kinases	Vertex Pharmaceuticals Inc	10/28/14	2D 3D TSV
US8742115	35	35	HGNC:1604	Co-crystals and salts of CCR3-inhibitors	Boehringer Ingelheim International GmbH	10/28/14	2D 3D TSV
US8722692	731	722	HGNC:11491	Compounds and compositions as Syk kinase inhibitors	TBA	10/28/14	2D 3D TSV
US8742138	35	34		Compounds as hypoxia mimetics, and compositions and uses thereof	Betta Pharmaceuticals Co., Ltd	10/28/14	2D 3D TSV
US8729074	47	25	HGNC:8975 HGNC:3942	Inhibitors of PI3 kinase	Amgen Inc	10/28/14	2D 3D TSV
US8729078	50	50	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Hoffmann-La Roche Inc	10/28/14	2D 3D TSV
US8735395	13	5	HGNC:2536 HGNC:2537 HGNC:2545	Protease inhibitors	Medivir AB	10/28/14	2D 3D TSV
US8742158	44	43		Protease inhibitors	TaiMed Biologies, Inc.	10/28/14	2D 3D TSV
US8729061	248	62	HGNC:2527 HGNC:2536 HGNC:2537 HGNC:2545	Pyrrolidine derivatives	Hoffmann-La Roche Inc	10/28/14	2D 3D TSV
US8722877	5	5		7-deazapurine modulators of histone methyltransferase, and methods of use thereof	Epizyme Inc	10/20/14	2D 3D TSV
US8722683	231	77	HGNC:3023 HGNC:3024	Benzodioxole piperazine compounds	Hoffmann-La Roche Inc	10/20/14	2D 3D TSV
US8716478	12	12	HGNC:8780	Boron-containing small molecules	Anacor Pharmaceuticals Inc	10/20/14	2D 3D TSV
US8729273	31	31		Compounds effective as xanthine oxidase inhibitors, method for preparing the same, and pharmaceutical composition containing the same	LG Life Sciences Ltd	10/20/14	2D 3D TSV
US8722718	2	2		Inhibitors of C-FMS kinase	Janssen Pharmaceutica NV	10/20/14	2D 3D TSV
US8716296	11	10	HGNC:1780	Inhibitors of protein kinases	Ingenium Pharmaceuticals GmbH	10/20/14	2D 3D TSV
US8722709	57	57		Mineralocorticoid receptor antagonists	Boehringer Ingelheim International GmbH	10/20/14	2D 3D TSV
US8716285	65	65	HGNC:13315	N-hydroxy-benzamids for the treatment of cancer	Hoffmann-La Roche Inc	10/20/14	2D 3D TSV
US8716287	65	65	HGNC:1925	Pharmaceutical compounds	Sentinel Oncology Limited	10/20/14	2D 3D TSV
US8722896	588	315		Prokineticin receptor antagonists and uses thereof	The Regents of the University of California	10/20/14	2D 3D TSV
US8722895	34	24	HGNC:1232 HGNC:14661	Prolyl hydroxylase inhibitors and method of use	Akebia Therapeutics, Inc.	10/20/14	2D 3D TSV
US8722721	18	17	HGNC:6621	SEC-hydroxycyclohexyl derivatives	Hoffmann-La Roche Inc	10/20/14	2D 3D TSV
US8722890	54	5	HGNC:3763 HGNC:6307 HGNC:11393 HGNC:11390 HGNC:2637 HGNC:6342 HGNC:3765	Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile	AbbVie Inc	10/20/14	2D 3D TSV
US8710076	8	4	HGNC:4849	2,5-disubstituted piperidine orexin receptor antagonists	Merck Sharp & Dohme Corp	10/14/14	2D 3D TSV
US8703785	9	9	HGNC:933	2-aminopyrimidin-4-one and 2-aminopyridine derivatives both having BACE1-inhibiting activity	Shionogi & Co., Ltd	10/14/14	2D 3D TSV
US8703807	12	12	HGNC:6621	Azaspirodecanone compounds	Hoffmann-La Roche Inc	10/14/14	2D 3D TSV
US8703947	11	10	HGNC:933	Compounds for treatment of Alzheimer's disease	Purdue Research Foundation	10/14/14	2D 3D TSV
US8703720	17	9	HGNC:6561 HGNC:6563	Galactoside inhibitors of galectins	Galecto Biotech AB	10/14/14	2D 3D TSV
US8710232	17	17	HGNC:2299	Imidazole derivatives used as TAFIa inhibitors	Sanofi-Aventis Deutschland GmbH	10/14/14	2D 3D TSV
US8703768	340	329	HGNC:8772	Nitrogen containing heteroaryl compounds	Hoffmann-La Roche Inc	10/14/14	2D 3D TSV
US8703761	15	15		Organic compounds	Novartis AG	10/14/14	2D 3D TSV
US8703771	45	12	HGNC:8804 HGNC:76 HGNC:6342	Preparation method of dihydroindene amide compounds, their pharmaceutical compositions containing compounds thereof and use as protein kinases inhibitor	Harbin Gloria Pharmaceuticals Co., Ltd.	10/14/14	2D 3D TSV
US8703770	2	2	HGNC:4849	Pyridazine carboxamide orexin receptor antagonists	Merck Sharp & Dohme Corp	10/14/14	2D 3D TSV
US8703811	138	95	HGNC:2867	Small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase	Genzyme Corporation	10/14/14	2D 3D TSV
US8703767	18	12	HGNC:1133	Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors	University of Utah Research Foundation	10/14/14	2D 3D TSV
US8716482	17	17	HGNC:3009	Substituted aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes	Merck Sharp & Dohme Corp	10/14/14	2D 3D TSV
US8697869	57	56	HGNC:4502	3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators	Actelion Pharmaceuticals Ltd	10/06/14	2D 3D TSV
US8697868	10	10	HGNC:3009	8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions	Boehringer Ingelheim International GmbH	10/06/14	2D 3D TSV
US8697708	16	16	HGNC:12440	Azabenzothiazole compounds, compositions and methods of use	F. Hoffmann-La Roche Inc	10/06/14	2D 3D TSV
US8697716	17	17	HGNC:6342	Method of inhibiting C-KIT kinase	Janssen Pharmaceutica NV	10/06/14	2D 3D TSV
US8691753	866	103	HGNC:7173 HGNC:7174 HGNC:7175 HGNC:7176 HGNC:7155 HGNC:7166 HGNC:7156 HGNC:7158 HGNC:7159	Pseudodipeptides as MMP inhibitors	Commissariat A l'Energie Atomique et Aux Energies Alternatives	10/06/14	2D 3D TSV
US8697911	172	116	HGNC:10252	Rho kinase inhibitors	Boehringer Ingelheim International GmbH	10/06/14	2D 3D TSV
US8697715	42	42	HGNC:6871	Serine/threonine kinase inhibitors	Array BioPharma Inc	10/06/14	2D 3D TSV
US8697696	11	11	HGNC:4079	Triazole compounds II	Roche Palo Alto LLC	10/06/14	2D 3D TSV
US8691852	26	26	HGNC:2867	Amino nicotinic and isonicotinic acid derivatives as DHODH inhibitors	Amirall, S.A.	09/30/14	2D 3D TSV
US8691827	9	9	HGNC:8772	Amino tetrahydro-pyridopyrimidine PDE10 inhibitors	Merck Sharp & Dohme Corp	09/30/14	2D 3D TSV
US8691986	34	17	HGNC:8772	Azetidine and piperidine compounds useful as PDE10 inhibitors	Amgen Inc	09/30/14	2D 3D TSV
US8691856	2	2	HGNC:4192	Glucagon receptor antagonists, preparation and therapeutic uses	Eli Lilly and Company	09/30/14	2D 3D TSV
US8691840	5	5		N-biarylamides	Bayer Intellectual Property GmbH	09/30/14	2D 3D TSV
US8691993	13	13	HGNC:4502	Piperidinyl naphthylacetic acids	Hoffmann-La Roche Inc	09/30/14	2D 3D TSV
US8685958	20	16	HGNC:4479	Therapeutic agents	AstraZeneca AB	09/30/14	2D 3D TSV
US8691829	4	4	HGNC:8977	Treatment of liver disorders with PI3K inhibitors	Gilead Calistoga LLC	09/30/14	2D 3D TSV
US8691832	20	20	HGNC:3009	Tricyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors	Merck Sharp & Dohme Corp	09/30/14	2D 3D TSV
US8680119	4	4		Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	09/16/14	2D 3D TSV
US8680275	351	173	HGNC:4849 HGNC:4848	Fused heterocyclic compounds as orexin receptor modulators	Janssen Pharmaceutica NV	09/16/14	2D 3D TSV
US8686042	2	2	HGNC:4617	GSK-3 inhibitors	Neuropharma, S.A.	09/16/14	2D 3D TSV
US8685992	120	18	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Histone deacetylase inhibitors based simultaneously on trisubstituted 1H-pyrroles and aromatic and heteroaromatic spacers	Universidad del País Vasco	09/16/14	2D 3D TSV
US8680120	31	31		Indole derivative or pharmaceutically acceptable salt thereof	Kissei Pharmaceutical Co., Ltd	09/16/14	2D 3D TSV
US8685986	12	12	HGNC:9594	Medical composition for treatment or prophylaxis of glaucoma	Ube Industries, Ltd	09/16/14	2D 3D TSV
US8686018	9	9	HGNC:9596	Pharmaceutical composition	Eisai R&D Management Co., Ltd	09/16/14	2D 3D TSV
US8680116	9	9		Quinolinone PDE2 inhibitors	Merck Sharp & Dohme Corp	09/16/14	2D 3D TSV
US8680132	72	48	HGNC:6973	Spiro-oxindole MDM2 antagonists	University of Michigan	09/16/14	2D 3D TSV
US8673938	23	23	HGNC:5208	Chemical compounds	AstraZeneca AB	09/08/14	2D 3D TSV
US8673906	102	93	HGNC:8976	Chromenone derivatives	AstraZeneca AB	09/08/14	2D 3D TSV
US8673950	149	75		Dihydrooxazol-2-amine derivatives	Hoffmann-La Roche Inc	09/08/14	2D 3D TSV
US8669380	8	5	HGNC:11037	Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives	Pfizer Inc	09/08/14	2D 3D TSV
US8673905	42	42	HGNC:3765	Imidazo pyrazines	Hoffmann-La Roche Inc	09/08/14	2D 3D TSV
US8669252	14	14	HGNC:9344	Prolylcarboxypeptidase inhibitors	Merck Sharp & Dohme Corp	09/08/14	2D 3D TSV
US8669361	86	29	HGNC:19310 HGNC:8987	Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	F. Hoffmann-La Roche Inc	09/08/14	2D 3D TSV
US8669266	17	17	HGNC:18124	Quinoline-carboxamide derivatives as P2Y12 antagonists	Sanofi	09/08/14	2D 3D TSV
US8673966	123	41	HGNC:6833 HGNC:6834 HGNC:404	ALDH-2 inhibitors in the treatment of addiction	Gilead Sciences Inc	09/03/14	2D 3D TSV
US8674113	185	180	HGNC:9599	Compounds	Boehringer Ingelheim International GmbH	09/03/14	2D 3D TSV
US8653125	23	23		Cyclohexane derivative having NPY Y5 receptor antagonism	Shionogi Co., Ltd.	09/03/14	2D 3D TSV
US8653263	733	377	HGNC:4849 HGNC:4848	Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators	Janssen Pharmaceutica NV	09/03/14	2D 3D TSV
US8674100	93	85		Inhibitors of C-FMS kinase	Janssen Pharmaceutica NV	09/03/14	2D 3D TSV
US8653111	20	20	HGNC:14660	Substituted dihydropyrazolones for treating cardiovascular and hematological diseases	Bayer Intellectual Property GmbH	09/03/14	2D 3D TSV
US8653092	188	94	HGNC:8975 HGNC:8977	Tetrahydro-pyrido-pyrimidine derivatives	Novartis AG	09/03/14	2D 3D TSV
US8664236	35	35	HGNC:8816	1H-pyrrolo[2,3 b]-pyridine derivatives	Merck Patent GmbH	08/26/14	2D 3D TSV
US8664219	26	12	HGNC:4617 HGNC:4616	Aminopyrimidines useful as inhibitors of protein kinases	Vertex Pharmaceuticals Inc	08/26/14	2D 3D TSV
US8648092	144	141	HGNC:4852	Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications	Mei Pharma Inc	08/26/14	2D 3D TSV
US8664258	5	5		Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	08/26/14	2D 3D TSV
US8653091	46	46	HGNC:8534	Pyrid-2yl fused heterocyclic compounds, and compositions and uses thereof	Evotec AG	08/26/14	2D 3D TSV
US8653087	741	737		Pyrido [5, 4-D] pyrimidines as cell proliferation inhibitors	Boehringer Ingelheim International GmbH	08/26/14	2D 3D TSV
US8664230	18	6	HGNC:8979 HGNC:8978 HGNC:8977	Pyridopyrimidine derivatives and use thereof	The Asan Foundation	08/26/14	2D 3D TSV
US8637558	130	124	HGNC:5154	Thiazolidinedione derivative and use thereof	Industry-Academic Cooperation Foundation, Chosun University	08/26/14	2D 3D TSV
US8637502	75	31	HGNC:8153 HGNC:8154 HGNC:8155 HGNC:8156	2,3,4,5-tetrahydro-benzo{B}{1,4}diazepine-comprising compounds of formula(III) for treating pain	Purde Pharma L.P.	08/22/14	2D 3D TSV
US8633183	1192	574	HGNC:8975 HGNC:3942	5-alkynyl-pyrimidines	Boehringer Ingelheim International GmbH	08/22/14	2D 3D TSV
US8637532	1511	692	HGNC:8816 HGNC:10436 HGNC:11393 HGNC:11390	Amino azaheterocyclic carboxamides	Merck Patent GmbH	08/22/14	2D 3D TSV
US8637500	360	351		Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors	Amgen Inc	08/22/14	2D 3D TSV
US8637508	90	45	HGNC:934 HGNC:933	Heterocyclic derivatives and their use in the treatment of neurological disorders	Novartis AG	08/22/14	2D 3D TSV
US8637526	40	10	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolopyrimidine JAK inhibitor compounds and methods	Genentech Inc	08/22/14	2D 3D TSV
US8637504	37	37	HGNC:933	Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity	Shionogi & Co., Ltd	08/22/14	2D 3D TSV
US8637528	8	4	HGNC:8791 HGNC:8792	Use of PDE7 inhibitors for the treatment of movement disorders	Omeros Corporation	08/22/14	2D 3D TSV
US8633204	174	173	HGNC:8975	4-methylpyridopyrimidinone compounds	Pfizer Inc	08/06/14	2D 3D TSV
US8633208	48	24	HGNC:6833 HGNC:6834	6-1H-imidazo-quinazoline and quinolines derivatives, new MAO inhibitors and imidazoline receptor ligands	Rottapharm S.p.A	08/06/14	2D 3D TSV
US8633188	60	60	HGNC:933	Aminodihydrothiazine derivatives	Shionogi & Co., Ltd	08/06/14	2D 3D TSV
US8637501	113	111	HGNC:4479	Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof	Albany Molecular Research, Inc.	08/06/14	2D 3D TSV
US8633196	19	18	HGNC:195	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics	Galderma Research & Development	08/06/14	2D 3D TSV
US8637507	15	14	HGNC:2843	Bicyclic compounds as inhibitors of diacylglycerol acyltransferase	Merck Sharp & Dohme Corp	08/06/14	2D 3D TSV
US8633212	166	163		Inhibitors of beta-secretase	Vitae Pharmaceuticals Inc	08/06/14	2D 3D TSV
US8633226	5	5	HGNC:1602	Piperidinyl derivative as a modulator of chemokine receptor activity	Bristol-Myers Squibb Co.	08/06/14	2D 3D TSV
US8633206	417	139	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolo[2,3-D]pyrimidine compounds	Pfizer Inc	08/06/14	2D 3D TSV
US8633231	20	20	HGNC:4192	Substituted imidazolones, compositions containing such compounds and methods of use	Merck Sharp & Dohme Corp	08/05/14	2D 3D TSV
US8629158	46	40	HGNC:4479	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof	Albany Molecular Research, Inc.	07/28/14	2D 3D TSV
US8623860	151	150	HGNC:85	Azetidine derivatives, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	07/28/14	2D 3D TSV
US8623863	24	12	HGNC:4849	Disubstituted azepan orexin receptor antagonists	Merck Sharp & Dohme Corp	07/28/14	2D 3D TSV
US8629282	13	13	HGNC:3165	Heterocyclic compounds as S1P1 agonists for the treatment of autoimmune and vascular diseases	Bristol-Myers Squibb Co.	07/28/14	2D 3D TSV
US8629135	14	13	HGNC:9967	Pharmaceutical compositions comprising RET inhibitors and methods for the treatment of cancer	Queen's University at Kingston	07/28/14	2D 3D TSV
US8629167	93	93		Selective androgen receptor modulators	Radius Health, Inc.	07/28/14	2D 3D TSV
US8628961	13	7	HGNC:391 HGNC:8816 HGNC:9504	Small molecule antagonists of phosphatidylinositol-3,4,5-triphosphate (PIP3) and uses thereof	Tufts University	07/28/14	2D 3D TSV
US8629141	39	39	HGNC:6973	Spiro-oxindole MDM2 antagonists	University of Michigan	07/28/14	2D 3D TSV
US8629154	10	5	HGNC:5301	Substituted cycloalcano[e and d] pyrazolo [1,5-a]pyrimidines/antagonists of serotonin 5-HT6 receptors and methods for production and the use thereof	TBA	07/28/14	2D 3D TSV
US8623883	20	7	HGNC:3432 HGNC:3430 HGNC:3236	4-phenylamino-quinazolin-6-yl-amides	Warner-Lambert Company LLC	07/22/14	2D 3D TSV
US8623865	3	3		Acylpiperazinones and their use as pharmaceuticals	Fab Pharma S.A.S.	07/22/14	2D 3D TSV
US8623901	43	43	HGNC:8795	Compounds for the treatment of CNS disorders	Boehringer Ingelheim International GmbH	07/22/14	2D 3D TSV
US8623885	48	26	HGNC:1773 HGNC:3765	Fused tricyclic dual inhibitors of CDK 4/6 and FLT3	Amgen Inc	07/22/14	2D 3D TSV
US8618103	236	119	HGNC:6192 HGNC:6193	Inhibitors of JAK	Hoffmann-La Roche Inc	07/22/14	2D 3D TSV
US8623892	13	4	HGNC:2593 HGNC:2637 HGNC:2623 HGNC:2621	Metalloenzyme inhibitor compounds	Viamet Pharmaceuticals Inc	07/22/14	2D 3D TSV
US8618107	64	64	HGNC:1133	Pyridone and aza-pyridone compounds and methods of use	Gilead Connecticut, Inc.	07/22/14	2D 3D TSV
US8623889	490	427	HGNC:76	Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof	Genentech Inc	07/22/14	2D 3D TSV
US8623906	70	67	HGNC:9644	Carboxy isatin hydrazones and their esters as Shp2 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	07/21/14	2D 3D TSV
US8618114	79	55	HGNC:5301	Substituted 3-arylsulfonyl-pyrazolo[1,5-A]pyrimidines, serotonin 5-HT6 receptor antagonists and methods for the production and use thereof	TBA	07/09/14	2D 3D TSV
US8618111	284	141	HGNC:8975 HGNC:3942	5-alkynyl-pyrimidines	Boehringer Ingelheim International GmbH	07/08/14	2D 3D TSV
US8618286	87	29	HGNC:7872 HGNC:7873	Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity	NeurAxon Inc	07/08/14	2D 3D TSV
US8618075	9	9	HGNC:1712	Certain compounds, compositions and methods	Eisai Inc.	07/08/14	2D 3D TSV
US8623903	17	17	HGNC:4502	Indolecarboxylic acid derivative having PGD2 receptor antagonistic activity	Shionogi & Co., Ltd	07/08/14	2D 3D TSV
US8618098	4	4	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Roche Palo Alto LLC	07/08/14	2D 3D TSV
US8618147	16	16		Modified macrophage migration inhibitory factor inhibitors	The Feinstein Institute for Medical Research	07/08/14	2D 3D TSV
US8624022	14	7		Substituted aniline derivatives	UCB Pharma SA	07/08/14	2D 3D TSV
US8618158	80	78	HGNC:6973	Therapeutic agents	Cancer Research Technology Limited	07/08/14	2D 3D TSV
US8614253	302	272	HGNC:3449	IRE-1α inhibitors	MannKind Corporation	06/25/14	2D 3D TSV
US8614234	165	146	HGNC:3763 HGNC:6307	Compounds as tyrosine kinase modulators	Allergan Inc	06/24/14	2D 3D TSV
US8618290	17	17	HGNC:5253	HSP90 inhibitors	Takeda Pharmaceutical Co., Ltd	06/24/14	2D 3D TSV
US8613914	197	197		Peptidomimetic sulfamide compounds and antiviral uses thereof	Novartis AG	06/24/14	2D 3D TSV
US8614206	289	215		Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	F. Hoffmann-La Roche Inc	06/24/14	2D 3D TSV
US8614215	103	103	HGNC:8978	Quinoxaline inhibitors of phosphoinositide-3-kinases (PI3Ks)	Merck Serono	06/24/14	2D 3D TSV
US8618299	55	52	HGNC:4479	Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof	Albany Molecular Research, Inc.	06/16/14	2D 3D TSV
US8609647	91	67	HGNC:6192 HGNC:6193	Nitrogen-containing spirocyclic compounds and pharmaceutical uses thereof	Japan Tobacco Inc	06/16/14	2D 3D TSV
US8618303	36	35	HGNC:11528	Pyrrolidine derivatives	Hoffmann-La Roche Inc	06/16/14	2D 3D TSV
US8609678	365	176	HGNC:14064	Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof	Acetylon Pharmaceuticals Inc	06/16/14	2D 3D TSV
US8609681	72	24	HGNC:2527 HGNC:2536 HGNC:2545	Spirocyclic nitriles as protease inhibitors	Sanofi	06/16/14	2D 3D TSV
US8609708	141	89	HGNC:2637 HGNC:2610	Synthetic compounds and derivatives as modulators of smoking or nicotine ingestion and lung cancer	Human BioMolecular Research Institute	06/16/14	2D 3D TSV
US8604061	221	221		2-aminooxazolines as TAAR1 ligands	Hoffmann-La Roche Inc	06/04/14	2D 3D TSV
US8609666	67	67	HGNC:8975	2-morpholino-pyrido[3,2-D]pyrimidines	Merck Serono	06/04/14	2D 3D TSV
US8609622	20	7		C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof	Shanghai Hengrui Pharmaceutical Co., Ltd	06/04/14	2D 3D TSV
US8609710	29	29	HGNC:2300	Cycloalkyl-substituted imidazole derivative	Daiichi Sankyo Company, Limited	06/04/14	2D 3D TSV
US8609715	258	129	HGNC:9490 HGNC:9475	Heteroarylcarboxylic acid ester derivative	Ajinomoto Co. Inc	06/04/14	2D 3D TSV
US8609698	8	8	HGNC:28858	Substituted dipyridyl-dihydropyrazolones and use thereof	Bayer Intellectual Property GmbH	06/04/14	2D 3D TSV
US8604028	6	6	HGNC:7029	Furopyridinyl-substituted 1,4-dihydropyridine derivatives and methods of use thereof	Bayer Intellectual Property GmbH	05/13/14	2D 3D TSV
US8609852	103	102		Thiazolyl mGluR5 antagonists and methods for their use	Merck Sharp & Dohme Corp	05/13/14	2D 3D TSV
US8604206	18	7	HGNC:4177	Compositions for preventing and/or treating degenerative disorders of the central nervous system	Amicus Therapeutics, Inc	05/12/14	2D 3D TSV
US8604016	694	665		Heterocyclic inhibitors of glutaminase	Calithera Biosciences Inc	05/12/14	2D 3D TSV
US8609688	36	20	HGNC:391	Substituted imidazopyridinyl-aminopyridine compounds	ArQule Inc	05/12/14	2D 3D TSV
US8604217	78	78		Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent	Selvita S.A.	05/05/14	2D 3D TSV
US8609892	2	2	HGNC:4191	Glucagon receptor antagonists, preparation and therapeutic uses	Eli Lilly and Company	05/05/14	2D 3D TSV
US8598119	47	11	HGNC:3023 HGNC:11050 HGNC:5295 HGNC:277 HGNC:4714	Methods and compositions for sleep disorders and other disorders	Intra-Cellular Therapies Inc	05/05/14	2D 3D TSV
US8609833	18	6	HGNC:268 HGNC:262	Purine derivatives as adenosine A1 receptor agonists and methods of use thereof	Inotek Pharmaceuticals Corporation	05/05/14	2D 3D TSV
US8604046	69	69		Substituted piperidine spiro pyrrolidinone and piperidinone, preparation and therapeutic use thereof	Sanofi	05/05/14	2D 3D TSV
US8598157	90	89	HGNC:8975	5-alkynyl-pyridines	Boehringer Ingelheim International GmbH	04/28/14	2D 3D TSV
US8598163	45	24	HGNC:5208	Derivatives of [1,3]Oxazin-2-one useful for the treatment of metabolic diseases such as lipid disorders	Vitae Pharmaceuticals Inc	04/28/14	2D 3D TSV
US8598184	5	5	HGNC:7029	Protein kinase inhibitors	Tiger Pharmatech	04/28/14	2D 3D TSV
US8598172	6	2	HGNC:2154 HGNC:9077 HGNC:19699	Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors	Nerviano Medical Sciences srl	04/28/14	2D 3D TSV
US8598206	241	23	HGNC:9051 HGNC:3530 HGNC:9451 HGNC:6371 HGNC:3528 HGNC:3529 HGNC:1246 HGNC:4646 HGNC:9071 HGNC:1247	Trypsin-like serine protease inhibitors, and their preparation and use	The Medicines Company (Leipzig) GmbH	04/28/14	2D 3D TSV
US8604218	166	165	HGNC:10252	Cytoskeletal active rho kinase inhibitor compounds, composition and use	Inspire Pharmaceuticals, Inc.	04/18/14	2D 3D TSV
US8598155	86	84		Imidazo[5,1-f][1,2,4]triazines for the treatment of neurological disorders	Pfizer Inc	04/18/14	2D 3D TSV
US8598217	20	20		Imidazole derivatives and their use as modulators of cyclin dependent kinases	Astex Therapeutics Ltd	04/18/14	2D 3D TSV
US8598200	29	29	HGNC:17929	KAT II inhibitors	Pfizer Inc	04/18/14	2D 3D TSV
US8598210	55	24	HGNC:1232 HGNC:12680 HGNC:14661	Prolyl hydroxylase inhibitors and methods of use	Akebia Therapeutics, Inc.	04/18/14	2D 3D TSV
US8592371	8	8	HGNC:3009	Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes	Merck Sharpe & Dohme Corp.	04/14/14	2D 3D TSV
US8592426	124	60	HGNC:6383	Aryl-benzocycloalkyl amide derivatives	Hoffmann-La Roche Inc	04/14/14	2D 3D TSV
US8598357	237	79	HGNC:3023 HGNC:3024	Benzodioxole piperidine compounds	Hoffmann-La Roche Inc	04/14/14	2D 3D TSV
US8592432	61	61	HGNC:427	Compounds and compositions as protein kinase inhibitors	TBA	04/14/14	2D 3D TSV
US8592410	135	34	HGNC:2637 HGNC:5208 HGNC:2623 HGNC:2621	Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1	Vitae Pharmaceuticals Inc	04/14/14	2D 3D TSV
US8575157	341	109	HGNC:2637 HGNC:5208 HGNC:2623 HGNC:2621	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1	Vitae Pharmaceuticals Inc	04/14/14	2D 3D TSV
US8592431	151	145	HGNC:95	Fused ring compound and use thereof	Takeda Pharmaceutical Co., Ltd	04/14/14	2D 3D TSV
US8592425	5	5		Imidazo[1,2-a]pyridines and imidazo[1,2-b]pyridazines as mark inhibitors	Merck Sharp & Dohme Corp	04/14/14	2D 3D TSV
US8592423	3	3	HGNC:8772	Inhibitors of PDE10	Bristol-Myers Squibb Co.	04/14/14	2D 3D TSV
US8592379	11	9	HGNC:4510	Metastin derivative and use thereof	Kyoto University	04/14/14	2D 3D TSV
US8592415	144	36	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Selective kinase inhibitors	Reaction Biology Corp	04/14/14	2D 3D TSV
US8598345	91	77	HGNC:4597	Substituted heteroarylamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same	Vanderbilt University	04/14/14	2D 3D TSV
US8592468	14	14		Bacterial thioredoxin reductase inhibitors and methods for use thereof	Thioredoxin Systems AB	03/17/14	2D 3D TSV
US8592457	5	5	HGNC:4849	Isonicotinamide orexin receptor antagonists	Merck Sharp & Dohme Corp	03/17/14	2D 3D TSV
US8592455	417	139	HGNC:19310 HGNC:8987	Kinase inhibitors and methods of their use	Novartis AG	03/17/14	2D 3D TSV
US8592454	32	12	HGNC:11526 HGNC:11527 HGNC:11528	Nitrogen-containing heterocyclic compound and use of same	Takeda Pharmaceutical Co., Ltd	03/17/14	2D 3D TSV
US8592579	45	45	HGNC:5465	Pyrrolotriazine kinase inhibitors	Bristol-Myers Squibb Co.	03/17/14	2D 3D TSV
US8592581	36	16	HGNC:1780 HGNC:1771	Trisubstituted purine derivatives	Cyclacel Limited	03/17/14	2D 3D TSV
US8586580	8	8	HGNC:9611	2,7-substituted thieno[3,2-d] pyrimidine compounds as protein kinase inhibitors	Korea Institute of Science and Technology	03/12/14	2D 3D TSV
US8586617	104	103		Aminomethyl-4-imidazoles	Hoffmann-La Roche Inc	03/12/14	2D 3D TSV
US8586579	423	141	HGNC:3023 HGNC:3024	Anellated pyridine compounds	Hoffmann-La Roche Inc	03/12/14	2D 3D TSV
US8586571	15	15	HGNC:9922	Heterocyclic compound	Takeda Pharmaceutical Co., Ltd	03/12/14	2D 3D TSV
US8586600	34	14	HGNC:8803 HGNC:6307 HGNC:6342	Heterocyclic compounds and uses thereof	Celgene Avilomics Research, Inc.	03/12/14	2D 3D TSV
US8586620	134	53	HGNC:7872 HGNC:7873	Substituted indole compounds having NOS inhibitory activity	NeurAxon Inc	03/12/14	2D 3D TSV
US8580800	9	9	HGNC:3309	1,4-diaryl-pyrimidopyridazine-2,5-diones and their use	Bayer Intellectual Property GmbH	03/06/14	2D 3D TSV
US8586597	5	5	HGNC:8977	6-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)ethyl]-3H-quinazolin-4-one as an inhibitor of human phosphatidylinositol 3-kinase delta	ICOS Corporation	03/06/14	2D 3D TSV
US8575203	258	253	HGNC:8816	Chemical compounds	Boehringer Ingelheim International GmbH	03/06/14	2D 3D TSV
US8580788	21	7	HGNC:8153 HGNC:8154 HGNC:8156	Opioid antagonists	Adolor Corporation	03/06/14	2D 3D TSV
US8575197	752	750	HGNC:8534	Pyrolinone derivative and pharmaceutical composition comprising the same	Shionogi & Co., Ltd	03/06/14	2D 3D TSV
US8580778	9	9	HGNC:28858	Substituted dihydropyrazolones and their use	Bayer Intellectual Property GmbH	03/06/14	2D 3D TSV
US8580782	16	12	HGNC:1771	Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors	Merck Sharp & Dohme Corp	03/06/14	2D 3D TSV
US8575391	31	31	HGNC:6840	5-substituted-2-phenylamino benzamides as MEK inhibitors	Chugai Seiyaku Kabushiki Kaisha	02/24/14	2D 3D TSV
US8575375	5	5		Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties	Research Triangle Institute	02/24/14	2D 3D TSV
US8569291	11	10	HGNC:16709	Bicyclic dihydroimidazolone CGRP receptor antagonists	Merck Sharp & Dohme Corp	02/24/14	2D 3D TSV
US8569281	119	119	HGNC:18618	Compounds and their administration for treating a neurodegenerative disease as well as a method for identifying a compound capable of inhibiting a kinase, such as LRRK	Medical Research Council Technology	02/24/14	2D 3D TSV
US8580815	16	4	HGNC:76	Derivatives of azaindoles as inhibitors of protein kinases ABL and SRC	OriBase Pharma	02/24/14	2D 3D TSV
US8575186	219	152	HGNC:5301	Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof	Albany Molecular Research, Inc.	02/24/14	2D 3D TSV
US8569306	18	11	HGNC:6881 HGNC:6886	JNK modulators	Hoffmann-La Roche Inc	02/24/14	2D 3D TSV
US8569313	47	47	HGNC:11344	Meta-substituted phenyl sulfonyl amides of secondary amino acid amides, the production thereof, and use thereof as matriptase inhibitors	The Medicines Company (Leipzig) GmbH	02/24/14	2D 3D TSV
US8575364	66	66		Modulators of serotonin receptor	Janssen Pharmaceutica NV	02/24/14	2D 3D TSV
US8575201	175	173	HGNC:436	Oxadiazole inhibitors of leukotriene production	Boehringer Ingelheim International GmbH	02/24/14	2D 3D TSV
US8569299	10	10	HGNC:9344	Prolylcarboxypeptidase inhibitors	Merck Sharp & Dohme Corp	02/24/14	2D 3D TSV
US8569311	48	24		Pyridyl piperidine orexin receptor antagonists	Merch Sharp & Dohme Corp.	02/24/14	2D 3D TSV
US8569316	64	64		Pyrimido [5,4-D] pyrimidine derivatives for the inhibition of tyrosine kinases	Boehringer Ingelheim International GmbH	02/24/14	2D 3D TSV
USRE44599	5	5	HGNC:8977	Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta	ICOS Corporation	02/24/14	2D 3D TSV
US8575114	43	22	HGNC:11037 HGNC:11036	SGLT-2 inhibitors, methods of making them, and uses thereof	Albany Molecular Research, Inc.	02/24/14	2D 3D TSV
US8569308	118	87	HGNC:4597	Substituted heteroarylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same	Vanderbilt University	02/24/14	2D 3D TSV
US8569314	10	10	HGNC:3309	Triazolo and tetrazolo pyrimidine derivatives as HNE inhibitors for treating COPD	Bayer Intellectual Property GmbH	02/24/14	2D 3D TSV
US8575145	329	116	HGNC:8987	Triazolopyridine compounds as PIM kinase inhibitors	Array BioPharma Inc	02/24/14	2D 3D TSV
US8569521	10	10	HGNC:620	Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors	Merck Sharp & Dohme Corp	01/21/14	2D 3D TSV
US8569318	7	7	HGNC:5301	Tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines as antagonists of serotonin 5-HT6 receptors, methods for the production and use thereof	TBA	01/21/14	2D 3D TSV
US8569338	3	3	HGNC:550	Methods of using 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine compounds	Proximagen Ltd.	01/20/14	2D 3D TSV
US8563583	6	6	HGNC:4479	Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists	Bristol-Myers Squibb Co.	01/20/14	2D 3D TSV
US8569511	40	21	HGNC:8816	Substituted 3-(1H-benzo[d]imidazol-2-yl)-1H-indazole analogs as inhibitors of the PDK1 kinase	University of Utah Research Foundation	01/20/14	2D 3D TSV
US8562945	22	11	HGNC:1373 HGNC:1383 HGNC:3590 HGNC:3009	Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof	Molecular Insight Pharmaceuticals, Inc.	01/20/14	2D 3D TSV
US8551988	144	97	HGNC:4852 HGNC:13315	Benzimidazole derivatives: preparation and pharmaceutical applications	Mei Pharma Inc	01/14/14	2D 3D TSV
US8563545	42	11	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Compound useful for the treatment of degenerative and inflammatory diseases	Galapagos NV	01/14/14	2D 3D TSV
US8563553	103	103		Compounds and compositions as protein kinase inhibitors	Novartis AG	01/14/14	2D 3D TSV
US8551978	95	93	HGNC:1952	Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity	Theravance, Inc.	01/14/14	2D 3D TSV
US8551963	10	2	HGNC:3765	Imidazolothiazole compounds and methods of use thereof	Ambit Biosciences Corporation	01/14/14	2D 3D TSV
US8563594	17	16	HGNC:3167	S1P3 receptor inhibitors for treating pain	Allergan Inc	01/14/14	2D 3D TSV
US8552005	16	13	HGNC:5301	(EN) 3-sulfonyl-pyrazolo[1,5-a] pyrimidines / antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof	Avincuro Pharmaceuticals, Inc.	01/03/14	2D 3D TSV
US8552017	4	4	HGNC:5301	2-amino-3-sulphonyl-tetrahydro-pyrazolo[1,5-A]pyrido-pyrimidine antagonists of serotonin 5-HT6 receptors, methods for the production and use thereof	TBA	01/03/14	2D 3D TSV
US8552004	30	27	HGNC:882	Chemical compounds	AstraZeneca AB	01/03/14	2D 3D TSV
US8546370	24	23	HGNC:12858	Compounds and compositions as kinase inhibitors	IRM LLC	01/03/14	2D 3D TSV
US8552023	5	5	HGNC:16709	Non-amidic linkers with branched termini as CGRP receptor antagonists	Merck Sharp & Dohme Corp	01/03/14	2D 3D TSV
US8551989	12	8	HGNC:7029	Substituted 4-(indazolyl)-1,4-dihydropyridines and methods of use thereof	Bayer Intellectual Property GmbH	01/03/14	2D 3D TSV
US8546380	61	60	HGNC:933	Aminodihydrothiazine derivatives	Shionogi & Co., Ltd	12/22/13	2D 3D TSV
US8552202	105	21	HGNC:2538 HGNC:2527 HGNC:2536 HGNC:2537 HGNC:2545	Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors	Amura Therapeutics Limited	12/22/13	2D 3D TSV
US8552033	2	2	HGNC:6027	Inhibitors of CXCR2	Sanofi	12/22/13	2D 3D TSV
US8552057	12	8	HGNC:3467 HGNC:3468	Phytoestrogenic formulations for alleviation or prevention of neurodegenerative diseases	University of Southern California	12/22/13	2D 3D TSV
US8552037	42	21	HGNC:7463 HGNC:7464	Tricyclic compound and pharmaceutical use thereof	Takeda Pharmaceutical Co., Ltd	12/22/13	2D 3D TSV
US8546392	59	17	HGNC:5211 HGNC:5210 HGNC:2637 HGNC:2625 HGNC:2623 HGNC:2621	17Beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of hormone-related diseases	Universitaet des Saarlandes	12/09/13	2D 3D TSV
US8546404	17	14		Compounds that are ERK inhibitors	Merck Sharp & Dohme	12/09/13	2D 3D TSV
US8552199	24	24	HGNC:4479	Substituted indanes, method for the production thereof, and use thereof as drugs	Sanofi	12/09/13	2D 3D TSV
US8546434	14	14	HGNC:6388	Triazole compounds as KSP inhibitors	Novartis AG	12/09/13	2D 3D TSV
US8546389	76	38		Viral polymerase inhibitors	Biota Scientific Management Pty Ltd	12/09/13	2D 3D TSV
US8541380	97	97	HGNC:11037	C-aryl glucoside SGLT2 inhibitors and pharmaceutical compositions comprising same	Green Cross Corporation	12/03/13	2D 3D TSV
US8546451	20	10	HGNC:3467 HGNC:3468	Estrogen receptor ligands and methods of use thereof	GTX Inc	12/03/13	2D 3D TSV
US8541363	4	4		Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use	St George's Hosptial Medical School	12/03/13	2D 3D TSV
US8541407	230	230	HGNC:391	Substituted benzo-pyrido-triazolo-diazepine compounds	ArQule Inc	12/03/13	2D 3D TSV
US8546435	9	9	HGNC:4267	Triazole derivatives with improved receptor activity and bioavailability properties as ghrelin antagonists of growth hormone secretagogue receptors	AEterna Zentaris GmbH	12/03/13	2D 3D TSV
US8541447	6	6	HGNC:1960	3-substituted-2-(arlyalkyl)-1-azabicycloalkanes and methods of use thereof	Targacept Inc	11/26/13	2D 3D TSV
US8541408	48	48	HGNC:933	Aminodihydrothiazine derivatives substituted with a cyclic group	Shionogi & Co., Ltd	11/26/13	2D 3D TSV
US8541572	292	289	HGNC:11892	Compounds for the treatment of inflammatory disorders	Merck Sharp & Dohme Corp	11/26/13	2D 3D TSV
US8541596	10	10	HGNC:9753	Inhibitors	Probiodrug AG	11/26/13	2D 3D TSV
US8541427	45	43	HGNC:933	Phenyl-substituted 2-imino-3-methyl pyrrolo pyrimidinone compounds as BACE-1 inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	11/26/13	2D 3D TSV
US8536165	55	55	HGNC:2867	Azabiphenylaminobenzoic acid derivatives as DHODH inhibitors	Almirall, S.A.	11/18/13	2D 3D TSV
US8536158	8	8	HGNC:4502	Compounds having CRTH2 antagonist activity	Atopix Therapeutics Limited	11/18/13	2D 3D TSV
US8536166	4	4	HGNC:1133	Inhibitors of Burton's tyrosine kinase	Roche Palo Alto LLC	11/18/13	2D 3D TSV
US8536172	106	66	HGNC:6881	Inhibitors of JNK	Roche Palo Alto LLC	11/18/13	2D 3D TSV
US8536175	50	50	HGNC:3690	Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors	Novartis AG	11/18/13	2D 3D TSV
US8536173	10	10	HGNC:5208	Tetrahydroquinoxaline urea derivatives as modulators of 11-B-hydroxysteroid dehydrogenase type I	Sanofi	11/18/13	2D 3D TSV
US8536192	53	31		6,7-unsaturated-7-carbamoyl substituted morphinan derivative	Shionogi & Co., Ltd	11/11/13	2D 3D TSV
US8536210	19	19	HGNC:550	Compounds for inhibiting semicarbazide-sensitive amine oxidase (SSAO)/vascular adhesion protein-1 (VAP-1) and uses thereof for treatment and prevention of diseases	Semmelweis Egyetem	11/11/13	2D 3D TSV
US8536193	14	8	HGNC:391 HGNC:392	Inhibitors of AKT activity	Merck Sharp & Dohme Corp	11/11/13	2D 3D TSV
US8536198	23	23	HGNC:1602	Piperidine derivatives as modulators of chemokine receptor activity	Bristol-Myers Squibb Co.	11/11/13	2D 3D TSV
US8536181	32	16	HGNC:1232 HGNC:12680	Prolyl hydroxylase inhibitors	Aerpio Therapeutics Inc	11/11/13	2D 3D TSV
US8530460	200	199		Azetidine derivatives	Boehringer Ingelheim International GmbH	11/04/13	2D 3D TSV
US8530648	404	155	HGNC:4849 HGNC:4848	Diaza-spiro[5.5]undecanes	Novartis AG	11/04/13	2D 3D TSV
US8536227	10	10	HGNC:5465	Modulators of protein kinase signaling	Novotyr Therapeutics Ltd.	11/04/13	2D 3D TSV
US8530504	83	82	HGNC:2357	Pyrazolothiazole compound	Eisai R&D Management Co., Ltd	11/04/13	2D 3D TSV
US8530490	143	141	HGNC:3078	Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity	Taiho Pharmaceutical Co., Ltd	11/04/13	2D 3D TSV
US8530494	94	31	HGNC:8153 HGNC:8154 HGNC:8156 HGNC:21378	Buprenophine analogs	Purdue Pharma LP	10/25/13	2D 3D TSV
US8530670	5	5	HGNC:9753	Inhibitors	Probiodrug AG	10/25/13	2D 3D TSV
US8524716	27	26		Macrocyclic indoles as hepatitis C virus inhibitors	Janssen Ireland	10/25/13	2D 3D TSV
US8524710	86	83	HGNC:2545	Pyrrolidine derivatives	Hoffmann-La Roche Inc	10/25/13	2D 3D TSV
US8530652	86	82	HGNC:16059	Pyrrolopyrazoles, potent kinase inhibitors	Agouron Pharmaceuticals Inc	10/25/13	2D 3D TSV
US8524699	11	11	HGNC:28858	Substituted dihydropyrazolones and use thereof as HIF-prolyl-4-hydroxylase inhibitors	Bayer Intellectual Property GmbH	10/25/13	2D 3D TSV
US8507477	10	10	HGNC:16709	3- and 6-quinolines with N-attached heterocyclic CGRP receptor antagonists	Merck Sharp & Dohme Corp	10/18/13	2D 3D TSV
US8524917	157	154	HGNC:3167	6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity	Allergan Inc	10/18/13	2D 3D TSV
US8507479	48	48	HGNC:933	Aminodihydrothiazine derivatives substituted with a cyclic group	Shionogi & Co., Ltd	10/18/13	2D 3D TSV
US8524717	175	59	HGNC:6833 HGNC:6834 HGNC:29079	Oxidase inhibitors and their use	Oryzon Genomics, S.A.	10/18/13	2D 3D TSV
US8524722	21	21	HGNC:3236	Substituted tricyclic compounds and methods of use thereof	Bayer Intellectual Property GmbH	10/18/13	2D 3D TSV
US8507510	190	60	HGNC:6307 HGNC:1771 HGNC:1722	Sulfoximine-substituted pyrimidines as CDK- and/or VEGF inhibitors, their production and use as pharmaceutical agents	Bayer Intellectual Property GmbH	10/18/13	2D 3D TSV
US8524909	65	50		Tetrahydro-pyran derivatives	Hoffmann-La Roche Inc	10/18/13	2D 3D TSV
US8507714	18	17	HGNC:2097	7-membered ring compound and method of production and pharmaceutical application thereof	Daiichi Sankyo Company, Limited	10/07/13	2D 3D TSV
US8501732	211	210	HGNC:6881	Aminomethyl quinolone compounds	Hoffmann-La Roche Inc	10/07/13	2D 3D TSV
US8507683	7	7		Compounds for the treatment of hepatitis C	Bristol-Myers Squibb Co.	10/07/13	2D 3D TSV
US8507533	84	74	HGNC:4191	Glucagon receptor modulators	Pfizer Inc	10/07/13	2D 3D TSV
US8507676	92	88	HGNC:7029	Heterocyclic oxime compounds	Novartis AG	10/07/13	2D 3D TSV
US8507535	25	25	HGNC:11528	Methyl-pyrrolidine ether derivatives	Hoffmann-La Roche Inc	10/07/13	2D 3D TSV
US8501749	31	31	HGNC:2097	Azaquinazolinediones chymase inhibitors	Boehringer Ingelheim International GmbH	09/30/13	2D 3D TSV
US8501981	6	6	HGNC:6027	CXCR2 inhibitors	Sanofi	09/30/13	2D 3D TSV
US8501783	79	76	HGNC:3401	Conformationally restricted urea inhibitors of soluble epoxide hydrolase	The Regents of the University of California	09/30/13	2D 3D TSV
US8501944	20	4	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11491	Inhibitors of protein kinases	Portola Pharmaceuticals Inc	09/30/13	2D 3D TSV
US8501744	22	22	HGNC:2536	Piperazine compounds	Amura Therapeutics Limited	09/30/13	2D 3D TSV
US8501729	34	34	HGNC:5297	5-HT3 receptor modulators, methods of making, and use thereof	Albany Molecular Research, Inc.	09/16/13	2D 3D TSV
US8501961	20	20		HIV protease inhibitors and methods for using	Purdue Research Foundation	09/16/13	2D 3D TSV
US8501750	52	52	HGNC:336	Heterocyclic compound and use thereof	Takeda Pharmaceutical Co., Ltd	09/16/13	2D 3D TSV
US8501767	18	18		Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors	CSIR, Pretoria (ZA)	09/16/13	2D 3D TSV
US8501991	6	6	HGNC:14929	P53 activating compounds	University Court of the University of Dundee	09/16/13	2D 3D TSV
US8501936	1030	365	HGNC:6192 HGNC:6193 HGNC:9611	Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives	Cephalon Inc	09/16/13	2D 3D TSV
US8497281	179	176	HGNC:5208	Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline	Vitae Pharmaceuticals Inc	09/10/13	2D 3D TSV
US8497274	6	6	HGNC:6840	Heterocyclic compound and use thereof	Takeda Pharmaceutical Co., Ltd	09/10/13	2D 3D TSV
US8497368	81	80	HGNC:7029	Heterocyclic hydrazone compounds	Novartis AG	09/10/13	2D 3D TSV
US8501768	36	36	HGNC:6621	Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds	Hoffmann-La Roche Inc	09/10/13	2D 3D TSV
US8501708	57	18		Adenosine compounds and their use thereof	Inotek Pharmaceuticals Corporation	09/09/13	2D 3D TSV
US8497265	327	320		Heteroaryloxyheterocyclyl compounds as PDE10 inhibitors	Amgen Inc	09/09/13	2D 3D TSV
US8497385	6	6		Bryostatin analogues, synthetic methods and uses	The Board of Trustees of the Leland Stanford Junior University	09/03/13	2D 3D TSV
US8497288	40	40	HGNC:6621	Hexahydropyrroloimidazolone compounds	Hoffmann-La Roche Inc	09/03/13	2D 3D TSV
US8497277	12	9	HGNC:1133	Inhibitors of Bruton's tyrosine kinase	Pharmacyclics Inc	09/03/13	2D 3D TSV
US8497376	27	27		Inhibitors of c-fms kinase	Janssen Pharmaceutica NV	09/03/13	2D 3D TSV
US8497270	8	8		Macrocyclic integrase inhibitors	Elanco Animal Health Ireland Limited	09/03/13	2D 3D TSV
US8497286	18	17	HGNC:9958	Organic compounds	Novartis AG	09/03/13	2D 3D TSV
US8487093	224	111		ß-lactamase inhibitors	Merck Sharp & Dohme Corp	09/03/13	2D 3D TSV
US8470847	15	14	HGNC:3767	Derivatives of 7-alkynyl-1,8-Naphthyridones, Preparation Method Therefore and Use of Same in Therapeutics	Sanofi	08/29/13	2D 3D TSV
US8476306	120	29		Urokinase inhibitors, production and use thereof	The Medicines Company	08/29/13	2D 3D TSV
US8492394	16	15	HGNC:8772	(3-aryl-piperazin-1-yl), (2-aryl-morpholin-4-yl) and (2-aryl-thiomorpholin-4-yl) derivatives of 6,7-dialkoxy-quinazoline, 6,7-dialkoxyphtalazine and 6,7-dialkoxyisoquinoline as PDE10A enzyme inhibitors	H. Lundbeck A/S	08/28/13	2D 3D TSV
US8492387	9	9	HGNC:933	2-aminoimidazole beta-secretase inhibitors for the treatment of alzheimer's disease	Merck Sharp & Dohme Corp	08/28/13	2D 3D TSV
US8492392	17	17	HGNC:8772	Alkoxy tetrahydro-pyridopyrimidine PDE10 inhibitors	Merck Sharp & Dohme Corp	08/28/13	2D 3D TSV
US8492408	4	4	HGNC:4075	Benzimidazole derivatives and their use for modulating the GABAA receptor complex	Aniona APS	08/28/13	2D 3D TSV
US8492568	1	1	HGNC:18084	Chromane derivatives as TRPV3 modulators	Glenmark Pharamceuticals S.A.	08/28/13	2D 3D TSV
US8492564	11	11	HGNC:8154	Salvinorin derivatives and uses thereof	The McLean Hospital Corporation	08/28/13	2D 3D TSV
US8486940	185	184	HGNC:9753	Inhibitors	Probiodrug AG	08/19/13	2D 3D TSV
US8486989	1	1		Inhibitors of serine proteases, particularly HCV NS3-NS4A protease	Vertex Pharmaceuticals Inc	08/19/13	2D 3D TSV
US8481733	348	346	HGNC:19297	Substituted imidazopyr- and imidazotri-azines	OSI Pharmaceuticals LLC	08/19/13	2D 3D TSV
US8487111	8	4	HGNC:3528 HGNC:3535	Substituted oxazolidinones and their use	Bayer Intellectual Property GmbH	08/19/13	2D 3D TSV
US8492379	10	10		Translocator protein ligands	The University of Sydney	08/19/13	2D 3D TSV
US8486966	24	22	HGNC:6192 HGNC:8031	9-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer	AstraZeneca AB	08/12/13	2D 3D TSV
US8481536	323	262	HGNC:8804 HGNC:3395 HGNC:11283 HGNC:12841	Benzotriazine inhibitors of kinases	TargeGen Inc	08/12/13	2D 3D TSV
US8487096	5	5	HGNC:7029	Imidazo[1,2-B][1,2,4]triazines as C-MET inhibitors	Incyte Corporation	08/12/13	2D 3D TSV
US8481743	8	4	HGNC:8155 HGNC:8156	Phenylpropionamide compounds and the use thereof	Purdue Pharma LP	08/12/13	2D 3D TSV
US8481586	11	6	HGNC:19310 HGNC:8987	Pyrrolo[2,3-a] carbazoles and use thereof as PIM kinase inhibitors	Centre National de la Recherche Scientifique	08/12/13	2D 3D TSV
US8486953	20	10	HGNC:7110 HGNC:7111	Thienopyrimidines for pharmaceutical compositions	Boehringer Ingelheim International GmbH	08/12/13	2D 3D TSV
US8476225	66	66		Antiviral compounds	Gilead Sciences Inc	08/05/13	2D 3D TSV
US8486964	9	3	HGNC:5208	Fused pyrrolidino-cyclopropane derivatives as selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors	Merck Patent GmbH	08/05/13	2D 3D TSV
US8476267	8	8	HGNC:4617	Imidazo-, pyrazolopyrazines and imidazotriazines and their use	Bayer Intellectual Property GmbH	08/05/13	2D 3D TSV
US8481564	14	14		Inhibitors of c-fms kinase	Janssen Pharmaceutica NV	08/05/13	2D 3D TSV
US8476271	28	7	HGNC:8154 HGNC:8155 HGNC:8156	Substituted-quinoxaline-type bridged-piperidine compounds as ORL-1 modulators	Purdue Pharma LP	08/05/13	2D 3D TSV
US8476295	12	6		Bridged bicyclic RHO kinase inhibitor compounds, composition and use	Inspire	07/29/13	2D 3D TSV
US8476255	38	30		Histone deacetylase inhibitors	Orchid Chemicals & Pharmaceuticals Limited	07/29/13	2D 3D TSV
US8476284	14	12	HGNC:6735 HGNC:1133 HGNC:6524	Inhibitors of Bruton's tyrosine kinase	Pharmacyclics Inc	07/29/13	2D 3D TSV
US8470843	15	14	HGNC:6621	Azacyclic compounds	Hoffmann-La Roche Inc	07/24/13	2D 3D TSV
US8470888	8	6	HGNC:74	Botryllamides and method of inhibiting PGP in a mammal afflicted with cancer	The United States of America, as represented by the Secretary, Department of Health and Human Services	07/24/13	2D 3D TSV
US8470836	40	22	HGNC:16490 HGNC:18648 HGNC:3009 HGNC:14892	Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent	LG Life Sciences Ltd	07/24/13	2D 3D TSV
US8470841	39	33	HGNC:84	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof	Sanofi	07/24/13	2D 3D TSV
US8470837	44	44		MAPK/ERK kinase inhibitors	Takeda Pharmaceutical Co., Ltd	07/24/13	2D 3D TSV
US8470835	3	1	HGNC:6307 HGNC:11491	Pyrimidinecarboxamide derivatives as inhibitors of Syk kinase	Glaxo Group Limited	07/24/13	2D 3D TSV
US8470825	17	17	HGNC:270	Diazabenzo[de] anthracen-3-one compounds and methods for inhibiting PARP	Eisai Inc.	07/08/13	2D 3D TSV
US8470800	10	10	HGNC:262	Method of reducing intraocular pressure in humans	Inotek Pharmaceuticals Corporation	07/08/13	2D 3D TSV
US8470820	64	63	HGNC:8772	Nitrogen-containing heteroaryl derivatives	Hoffman-La Roche Inc	07/08/13	2D 3D TSV
US8470816	43	20	HGNC:11526 HGNC:11527 HGNC:11521	Nitrogen-containing heterocyclic compound and use thereof	Takeda Pharmaceutical Co., Ltd	07/08/13	2D 3D TSV
US20130102619	122	38	HGNC:4849 HGNC:4848	2-pyridyloxy-4-nitrile orexin receptor antagonists	TBA	06/25/13	2D 3D TSV
US20130089624	1	1	HGNC:882	Compounds useful as inhibitors of atr kinase	Vertex Pharmaceuticals Inc	06/24/13	2D 3D TSV