Affinity Data by Patent

Patent code US8993612

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152937 (US8993612, 20) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39.2	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152932 (US8993612, 6) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51.3	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152936 (US8993612, 18) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	53.4	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152935 (US8993612, 17) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	86.1	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152938 (US8993612, 21) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152933 (US8993612, 10) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152939 (US8993612, 30) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152930 (US8993612, 2) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152934 (US8993612, 12) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM152931 (US8993612, 5) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	383	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8993612 (2015) BindingDB Entry DOI: 10.7270/Q2CN72NK
Rhizen Pharmaceuticals SA US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%