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SMILES: O=C(Cn1nnc2ccccc12)Nc1ccc(cc1)-n1nc(cc1C1CC1)C1CC1

InChI Key: InChIKey=WAJHNVZTIHWGQY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152932   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium release-activated calcium channel protein 1


(Homo sapiens (Human))		BDBM152932
PNG
(US8993612, 6)
Show SMILES O=C(Cn1nnc2ccccc12)Nc1ccc(cc1)-n1nc(cc1C1CC1)C1CC1
Show InChI InChI=1S/C23H22N6O/c30-23(14-28-21-4-2-1-3-19(21)25-27-28)24-17-9-11-18(12-10-17)29-22(16-7-8-16)13-20(26-29)15-5-6-15/h1-4,9-13,15-16H,5-8,14H2,(H,24,30)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 51.3n/an/an/an/an/a37



Rhizen Pharmaceuticals SA

US Patent


Assay Description
Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...

US Patent US8993612 (2015)


BindingDB Entry DOI: 10.7270/Q2CN72NK
More data for this
Ligand-Target Pair