Affinity Data by Patent

Patent code US9108956

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161383 (US9108956, 7) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161384 (US9108956, 10 \| US9108956, 11 \| US9108956, 8 \| US9...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161377 (US9108956, 1 \| US9108956, 2 \| US9108956, 3 \| US910...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161382 (US9108956, 6) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161384 (US9108956, 10 \| US9108956, 11 \| US9108956, 8 \| US9...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	570	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161384 (US9108956, 10 \| US9108956, 11 \| US9108956, 8 \| US9...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	760	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161377 (US9108956, 1 \| US9108956, 2 \| US9108956, 3 \| US910...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	820	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161384 (US9108956, 10 \| US9108956, 11 \| US9108956, 8 \| US9...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161377 (US9108956, 1 \| US9108956, 2 \| US9108956, 3 \| US910...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161377 (US9108956, 1 \| US9108956, 2 \| US9108956, 3 \| US910...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM161377 (US9108956, 1 \| US9108956, 2 \| US9108956, 3 \| US910...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
NOVARTIS AG US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%