BDBM161383 US9108956, 7

SMILES: [O-]C(=O)CC1CCC(OC1)c1ccc(cc1)-c1ccc(Nc2nnc(o2)C2CCC2)cc1

InChI Key: InChIKey=HIHFZDGOQGUUEM-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM161383 (US9108956, 7) Show SMILES [O-]C(=O)CC1CCC(OC1)c1ccc(cc1)-c1ccc(Nc2nnc(o2)C2CCC2)cc1 Show InChI InChI=1S/C25H27N3O4/c29-23(30)14-16-4-13-22(31-15-16)19-7-5-17(6-8-19)18-9-11-21(12-10-18)26-25-28-27-24(32-25)20-2-1-3-20/h5-12,16,20,22H,1-4,13-15H2,(H,26,28)(H,29,30)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	4
NOVARTIS AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US9108956 (2015) BindingDB Entry DOI: 10.7270/Q22J69MT
					More data for this Ligand-Target Pair