BindingDB logo
myBDB logout

Patent code USRE46792

Compile Data Set for Download or QSAR
Found 103 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389041
PNG
(USRE46792, 43)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2c(F)cccc2OC)co1
Show InChI InChI=1S/C23H23FN2O5/c1-28-18-9-8-15(10-20(18)30-12-14-6-7-14)23-26-16(13-31-23)11-25-22(27)21-17(24)4-3-5-19(21)29-2/h3-5,8-10,13-14H,6-7,11-12H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389045
PNG
(USRE46792, 63)
Show SMILES COc1ccc(cc1OCC(C)C)-c1nc(CNC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C23H26N2O5/c1-15(2)13-29-21-11-16(9-10-20(21)28-4)23-25-17(14-30-23)12-24-22(26)18-7-5-6-8-19(18)27-3/h5-11,14-15H,12-13H2,1-4H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389069
PNG
(USRE46792, 157)
Show SMILES COc1ccc(cc1OC1CCCC=C1)-c1nc(CCC(=O)c2ncccc2C)co1 |c:14|
Show InChI InChI=1S/C25H26N2O4/c1-17-7-6-14-26-24(17)21(28)12-11-19-16-30-25(27-19)18-10-13-22(29-2)23(15-18)31-20-8-4-3-5-9-20/h4,6-8,10,13-16,20H,3,5,9,11-12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389073
PNG
(USRE46792, 170)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C24H25NO5/c1-27-21-6-4-3-5-19(21)20(26)11-10-18-15-30-24(25-18)17-9-12-22(28-2)23(13-17)29-14-16-7-8-16/h3-6,9,12-13,15-16H,7-8,10-11,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389078
PNG
(USRE46792, 182)
Show SMILES CCOc1ccc(cc1OCC)-c1nc(CCC(=O)c2ccccc2OCC)co1
Show InChI InChI=1S/C24H27NO5/c1-4-27-21-10-8-7-9-19(21)20(26)13-12-18-16-30-24(25-18)17-11-14-22(28-5-2)23(15-17)29-6-3/h7-11,14-16H,4-6,12-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389079
PNG
(USRE46792, 195)
Show SMILES CCCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC)c1
Show InChI InChI=1S/C24H27NO5/c1-4-14-29-21-9-7-6-8-19(21)20(26)12-11-18-16-30-24(25-18)17-10-13-22(27-3)23(15-17)28-5-2/h6-10,13,15-16H,4-5,11-12,14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389096
PNG
(USRE46792, 305)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccc(F)cc2OC(C)C)co1
Show InChI InChI=1S/C24H26FNO5/c1-5-29-23-12-16(6-11-21(23)28-4)24-26-18(14-30-24)8-10-20(27)19-9-7-17(25)13-22(19)31-15(2)3/h6-7,9,11-15H,5,8,10H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389106
PNG
(USRE46792, 330)
Show SMILES Cc1cccnc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCC=C)c1
Show InChI InChI=1S/C22H20F2N2O4/c1-3-11-28-19-12-15(6-9-18(19)30-22(23)24)21-26-16(13-29-21)7-8-17(27)20-14(2)5-4-10-25-20/h3-6,9-10,12-13,22H,1,7-8,11H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389114
PNG
(USRE46792, 338)
Show SMILES CCOc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C20H19F2N3O4/c1-3-27-16-9-13(6-7-15(16)29-20(21)22)19-25-14(11-28-19)10-24-18(26)17-12(2)5-4-8-23-17/h4-9,11,20H,3,10H2,1-2H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389030
PNG
(USRE46792, 3)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2ccccc2O)co1
Show InChI InChI=1S/C22H22N2O5/c1-27-19-9-8-15(10-20(19)28-12-14-6-7-14)22-24-16(13-29-22)11-23-21(26)17-4-2-3-5-18(17)25/h2-5,8-10,13-14,25H,6-7,11-12H2,1H3,(H,23,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389035
PNG
(USRE46792, 22)
Show SMILES COc1ccc(cc1OC1Cc2ccccc2C1)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C27H25N3O4/c1-17-6-5-11-28-25(17)26(31)29-15-21-16-33-27(30-21)20-9-10-23(32-2)24(14-20)34-22-12-18-7-3-4-8-19(18)13-22/h3-11,14,16,22H,12-13,15H2,1-2H3,(H,29,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389061
PNG
(USRE46792, 138)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H22N2O4/c1-4-26-19-12-15(7-10-18(19)25-3)21-23-16(13-27-21)8-9-17(24)20-14(2)6-5-11-22-20/h5-7,10-13H,4,8-9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389070
PNG
(USRE46792, 159)
Show SMILES COc1ccc(cc1OC1Cc2ccccc2C1)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C28H26N2O4/c1-18-6-5-13-29-27(18)24(31)11-10-22-17-33-28(30-22)21-9-12-25(32-2)26(16-21)34-23-14-19-7-3-4-8-20(19)15-23/h3-9,12-13,16-17,23H,10-11,14-15H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389072
PNG
(USRE46792, 169)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CCC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C23H25NO5/c1-15(2)29-22-13-16(9-12-21(22)27-4)23-24-17(14-28-23)10-11-19(25)18-7-5-6-8-20(18)26-3/h5-9,12-15H,10-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389080
PNG
(USRE46792, 208)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OC(C)C)co1
Show InChI InChI=1S/C26H29NO5/c1-17(2)32-23-7-5-4-6-21(23)22(28)12-11-20-16-31-26(27-20)19-10-13-24(29-3)25(14-19)30-15-18-8-9-18/h4-7,10,13-14,16-18H,8-9,11-12,15H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389085
PNG
(USRE46792, 276)
Show SMILES COc1ccc(cc1OCCC=C)-c1nc(CCC(=O)c2ccccc2OCCF)co1
Show InChI InChI=1S/C25H26FNO5/c1-3-4-14-30-24-16-18(9-12-23(24)29-2)25-27-19(17-32-25)10-11-21(28)20-7-5-6-8-22(20)31-15-13-26/h3,5-9,12,16-17H,1,4,10-11,13-15H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389086
PNG
(USRE46792, 278)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C24H25F2NO5/c1-15(2)32-22-12-16(8-11-21(22)29-3)24-27-17(13-31-24)9-10-19(28)18-6-4-5-7-20(18)30-14-23(25)26/h4-8,11-13,15,23H,9-10,14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389103
PNG
(USRE46792, 324)
Show SMILES CCC(CC)Oc1cc(ccc1OC)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H27N3O4/c1-5-18(6-2)30-20-12-16(9-10-19(20)28-4)23-26-17(14-29-23)13-25-22(27)21-15(3)8-7-11-24-21/h7-12,14,18H,5-6,13H2,1-4H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389107
PNG
(USRE46792, 331)
Show SMILES Cc1cccnc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCCC=C)c1
Show InChI InChI=1S/C23H22F2N2O4/c1-3-4-12-29-20-13-16(7-10-19(20)31-23(24)25)22-27-17(14-30-22)8-9-18(28)21-15(2)6-5-11-26-21/h3,5-7,10-11,13-14,23H,1,4,8-9,12H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389110
PNG
(USRE46792, 334)
Show SMILES CCOc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ccccc2OCC)co1
Show InChI InChI=1S/C23H23F2NO5/c1-3-28-19-8-6-5-7-17(19)18(27)11-10-16-14-30-22(26-16)15-9-12-20(31-23(24)25)21(13-15)29-4-2/h5-9,12-14,23H,3-4,10-11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389124
PNG
(USRE46792, 350)
Show SMILES CCCOc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ccccc2OCC)co1
Show InChI InChI=1S/C23H24F2N2O5/c1-3-11-30-20-12-15(9-10-19(20)32-23(24)25)22-27-16(14-31-22)13-26-21(28)17-7-5-6-8-18(17)29-4-2/h5-10,12,14,23H,3-4,11,13H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389128
PNG
(USRE46792, 354)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCCC=C)c1
Show InChI InChI=1S/C24H24F2N2O5/c1-3-5-12-31-21-13-16(10-11-20(21)33-24(25)26)23-28-17(15-32-23)14-27-22(29)18-8-6-7-9-19(18)30-4-2/h3,6-11,13,15,24H,1,4-5,12,14H2,2H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389042
PNG
(USRE46792, 44)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2ccccc2SC)co1
Show InChI InChI=1S/C23H24N2O4S/c1-27-19-10-9-16(11-20(19)28-13-15-7-8-15)23-25-17(14-29-23)12-24-22(26)18-5-3-4-6-21(18)30-2/h3-6,9-11,14-15H,7-8,12-13H2,1-2H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389052
PNG
(USRE46792, 108)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCCC=C)c1
Show InChI InChI=1S/C25H27NO5/c1-4-6-15-30-24-16-18(11-14-23(24)28-3)25-26-19(17-31-25)12-13-21(27)20-9-7-8-10-22(20)29-5-2/h4,7-11,14,16-17H,1,5-6,12-13,15H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389075
PNG
(USRE46792, 174)
Show SMILES COc1ccc(cc1OCC=C)-c1nc(CCC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C23H23NO5/c1-4-13-28-22-14-16(9-12-21(22)27-3)23-24-17(15-29-23)10-11-19(25)18-7-5-6-8-20(18)26-2/h4-9,12,14-15H,1,10-11,13H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389076
PNG
(USRE46792, 177)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OCC=C)co1
Show InChI InChI=1S/C26H27NO5/c1-3-14-30-23-7-5-4-6-21(23)22(28)12-11-20-17-32-26(27-20)19-10-13-24(29-2)25(15-19)31-16-18-8-9-18/h3-7,10,13,15,17-18H,1,8-9,11-12,14,16H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389087
PNG
(USRE46792, 280)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C23H23F2NO5/c1-3-29-21-12-15(8-11-20(21)28-2)23-26-16(13-31-23)9-10-18(27)17-6-4-5-7-19(17)30-14-22(24)25/h4-8,11-13,22H,3,9-10,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389095
PNG
(USRE46792, 304)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccc(F)cc2OCC)co1
Show InChI InChI=1S/C23H24FNO5/c1-4-28-21-13-16(24)7-9-18(21)19(26)10-8-17-14-30-23(25-17)15-6-11-20(27-3)22(12-15)29-5-2/h6-7,9,11-14H,4-5,8,10H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389098
PNG
(USRE46792, 311)
Show SMILES CCC(C)Oc1cc(ccc1OC)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H26N2O4/c1-5-16(3)29-21-13-17(8-11-20(21)27-4)23-25-18(14-28-23)9-10-19(26)22-15(2)7-6-12-24-22/h6-8,11-14,16H,5,9-10H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389100
PNG
(USRE46792, 314)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC(F)F)c1
Show InChI InChI=1S/C23H23F2NO5/c1-3-29-19-7-5-4-6-17(19)18(27)10-9-16-13-31-23(26-16)15-8-11-20(28-2)21(12-15)30-14-22(24)25/h4-8,11-13,22H,3,9-10,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389105
PNG
(USRE46792, 329)
Show SMILES CCCOc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H22F2N2O4/c1-3-11-28-19-12-15(6-9-18(19)30-22(23)24)21-26-16(13-29-21)7-8-17(27)20-14(2)5-4-10-25-20/h4-6,9-10,12-13,22H,3,7-8,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389115
PNG
(USRE46792, 339)
Show SMILES Cc1cccnc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC=C)c1
Show InChI InChI=1S/C21H19F2N3O4/c1-3-9-28-17-10-14(6-7-16(17)30-21(22)23)20-26-15(12-29-20)11-25-19(27)18-13(2)5-4-8-24-18/h3-8,10,12,21H,1,9,11H2,2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389116
PNG
(USRE46792, 340)
Show SMILES CCCOc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H21F2N3O4/c1-3-9-28-17-10-14(6-7-16(17)30-21(22)23)20-26-15(12-29-20)11-25-19(27)18-13(2)5-4-8-24-18/h4-8,10,12,21H,3,9,11H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389117
PNG
(USRE46792, 341)
Show SMILES CC(C)Oc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H21F2N3O4/c1-12(2)29-17-9-14(6-7-16(17)30-21(22)23)20-26-15(11-28-20)10-25-19(27)18-13(3)5-4-8-24-18/h4-9,11-12,21H,10H2,1-3H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389119
PNG
(USRE46792, 343)
Show SMILES Cc1cccnc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCCC=C)c1
Show InChI InChI=1S/C22H21F2N3O4/c1-3-4-10-29-18-11-15(7-8-17(18)31-22(23)24)21-27-16(13-30-21)12-26-20(28)19-14(2)6-5-9-25-19/h3,5-9,11,13,22H,1,4,10,12H2,2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389120
PNG
(USRE46792, 344)
Show SMILES CC(C)COc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H23F2N3O4/c1-13(2)11-29-18-9-15(6-7-17(18)31-22(23)24)21-27-16(12-30-21)10-26-20(28)19-14(3)5-4-8-25-19/h4-9,12-13,22H,10-11H2,1-3H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389122
PNG
(USRE46792, 348)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC(C)C)c1
Show InChI InChI=1S/C24H26F2N2O5/c1-4-30-19-8-6-5-7-18(19)22(29)27-12-17-14-32-23(28-17)16-9-10-20(33-24(25)26)21(11-16)31-13-15(2)3/h5-11,14-15,24H,4,12-13H2,1-3H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389127
PNG
(USRE46792, 353)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC2CC2)c1
Show InChI InChI=1S/C24H24F2N2O5/c1-2-30-19-6-4-3-5-18(19)22(29)27-12-17-14-32-23(28-17)16-9-10-20(33-24(25)26)21(11-16)31-13-15-7-8-15/h3-6,9-11,14-15,24H,2,7-8,12-13H2,1H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389034
PNG
(USRE46792, 21)
Show SMILES COc1ccc(cc1OCC=C)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H21N3O4/c1-4-10-27-18-11-15(7-8-17(18)26-3)21-24-16(13-28-21)12-23-20(25)19-14(2)6-5-9-22-19/h4-9,11,13H,1,10,12H2,2-3H3,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389049
PNG
(USRE46792, 102)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC2CC2)c1
Show InChI InChI=1S/C25H27NO5/c1-3-29-22-7-5-4-6-20(22)21(27)12-11-19-16-31-25(26-19)18-10-13-23(28-2)24(14-18)30-15-17-8-9-17/h4-7,10,13-14,16-17H,3,8-9,11-12,15H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389050
PNG
(USRE46792, 103)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccccc2OCC)co1
Show InChI InChI=1S/C23H25NO5/c1-4-27-20-9-7-6-8-18(20)19(25)12-11-17-15-29-23(24-17)16-10-13-21(26-3)22(14-16)28-5-2/h6-10,13-15H,4-5,11-12H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389058
PNG
(USRE46792, 132)
Show SMILES CCOc1cccnc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OC2CCCC2)c1
Show InChI InChI=1S/C25H28N2O5/c1-3-30-22-9-6-14-26-24(22)20(28)12-11-18-16-31-25(27-18)17-10-13-21(29-2)23(15-17)32-19-7-4-5-8-19/h6,9-10,13-16,19H,3-5,7-8,11-12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389060
PNG
(USRE46792, 137)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H24N2O4/c1-15-4-3-11-24-22(15)19(26)9-8-18-14-29-23(25-18)17-7-10-20(27-2)21(12-17)28-13-16-5-6-16/h3-4,7,10-12,14,16H,5-6,8-9,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389063
PNG
(USRE46792, 140)
Show SMILES COc1ccc(cc1OCC=C)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H22N2O4/c1-4-12-27-20-13-16(7-10-19(20)26-3)22-24-17(14-28-22)8-9-18(25)21-15(2)6-5-11-23-21/h4-7,10-11,13-14H,1,8-9,12H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389065
PNG
(USRE46792, 143)
Show SMILES CCCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H24N2O4/c1-4-12-27-20-13-16(7-10-19(20)26-3)22-24-17(14-28-22)8-9-18(25)21-15(2)6-5-11-23-21/h5-7,10-11,13-14H,4,8-9,12H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389066
PNG
(USRE46792, 146)
Show SMILES COc1ccc(cc1OCCC=C)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H24N2O4/c1-4-5-13-28-21-14-17(8-11-20(21)27-3)23-25-18(15-29-23)9-10-19(26)22-16(2)7-6-12-24-22/h4,6-8,11-12,14-15H,1,5,9-10,13H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389071
PNG
(USRE46792, 166)
Show SMILES COc1ccc(cc1OCC=C)-c1nc(CCC(=O)c2ccccc2OCC=C)co1
Show InChI InChI=1S/C25H25NO5/c1-4-14-29-22-9-7-6-8-20(22)21(27)12-11-19-17-31-25(26-19)18-10-13-23(28-3)24(16-18)30-15-5-2/h4-10,13,16-17H,1-2,11-12,14-15H2,3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389083
PNG
(USRE46792, 274)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccccc2OC(F)F)co1
Show InChI InChI=1S/C22H21F2NO5/c1-3-28-20-12-14(8-11-19(20)27-2)21-25-15(13-29-21)9-10-17(26)16-6-4-5-7-18(16)30-22(23)24/h4-8,11-13,22H,3,9-10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389092
PNG
(USRE46792, 289)
Show SMILES CCOc1ccc(cc1OCC)-c1nc(CCC(=O)c2ccccc2OCCF)co1
Show InChI InChI=1S/C24H26FNO5/c1-3-28-22-12-9-17(15-23(22)29-4-2)24-26-18(16-31-24)10-11-20(27)19-7-5-6-8-21(19)30-14-13-25/h5-9,12,15-16H,3-4,10-11,13-14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389093
PNG
(USRE46792, 290)
Show SMILES CCOc1ccc(cc1OCC)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C24H25F2NO5/c1-3-29-21-12-9-16(13-22(21)30-4-2)24-27-17(14-32-24)10-11-19(28)18-7-5-6-8-20(18)31-15-23(25)26/h5-9,12-14,23H,3-4,10-11,15H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389121
PNG
(USRE46792, 345)
Show SMILES Cc1cccnc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC2CCC2)c1
Show InChI InChI=1S/C23H23F2N3O4/c1-14-4-3-9-26-20(14)21(29)27-11-17-13-31-22(28-17)16-7-8-18(32-23(24)25)19(10-16)30-12-15-5-2-6-15/h3-4,7-10,13,15,23H,2,5-6,11-12H2,1H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389033
PNG
(USRE46792, 19)
Show SMILES COc1ccc(cc1OCC(F)(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C20H18F3N3O4/c1-12-4-3-7-24-17(12)18(27)25-9-14-10-29-19(26-14)13-5-6-15(28-2)16(8-13)30-11-20(21,22)23/h3-8,10H,9,11H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389053
PNG
(USRE46792, 111)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OC(C)C)c1
Show InChI InChI=1S/C24H27NO5/c1-5-28-21-9-7-6-8-19(21)20(26)12-11-18-15-29-24(25-18)17-10-13-22(27-4)23(14-17)30-16(2)3/h6-10,13-16H,5,11-12H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389062
PNG
(USRE46792, 139)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H24N2O4/c1-14(2)28-20-12-16(7-10-19(20)26-4)22-24-17(13-27-22)8-9-18(25)21-15(3)6-5-11-23-21/h5-7,10-14H,8-9H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389067
PNG
(USRE46792, 153)
Show SMILES COc1ccc(cc1OCCC1CC1)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C24H26N2O4/c1-16-4-3-12-25-23(16)20(27)9-8-19-15-30-24(26-19)18-7-10-21(28-2)22(14-18)29-13-11-17-5-6-17/h3-4,7,10,12,14-15,17H,5-6,8-9,11,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389084
PNG
(USRE46792, 275)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CCC(=O)c2ccccc2OCCF)co1
Show InChI InChI=1S/C24H26FNO5/c1-16(2)31-23-14-17(8-11-22(23)28-3)24-26-18(15-30-24)9-10-20(27)19-6-4-5-7-21(19)29-13-12-25/h4-8,11,14-16H,9-10,12-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389088
PNG
(USRE46792, 281)
Show SMILES COc1ccc(cc1OCC=C)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C24H23F2NO5/c1-3-12-30-22-13-16(8-11-21(22)29-2)24-27-17(14-32-24)9-10-19(28)18-6-4-5-7-20(18)31-15-23(25)26/h3-8,11,13-14,23H,1,9-10,12,15H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389032
PNG
(USRE46792, 18)
Show SMILES COc1ccc(cc1OC1CCCC1)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H25N3O4/c1-15-6-5-11-24-21(15)22(27)25-13-17-14-29-23(26-17)16-9-10-19(28-2)20(12-16)30-18-7-3-4-8-18/h5-6,9-12,14,18H,3-4,7-8,13H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389046
PNG
(USRE46792, 76)
Show SMILES COc1ccc(cc1OCC(C)C)-c1nc(CNC(=O)c2ccccc2OC(C)C)co1
Show InChI InChI=1S/C25H30N2O5/c1-16(2)14-30-23-12-18(10-11-22(23)29-5)25-27-19(15-31-25)13-26-24(28)20-8-6-7-9-21(20)32-17(3)4/h6-12,15-17H,13-14H2,1-5H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389064
PNG
(USRE46792, 141)
Show SMILES COc1ccc(cc1OCC1CCC1)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C24H26N2O4/c1-16-5-4-12-25-23(16)20(27)10-9-19-15-30-24(26-19)18-8-11-21(28-2)22(13-18)29-14-17-6-3-7-17/h4-5,8,11-13,15,17H,3,6-7,9-10,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389090
PNG
(USRE46792, 284)
Show SMILES COc1ccc(cc1OCC(F)F)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C23H21F4NO5/c1-30-19-9-6-14(10-20(19)32-13-22(26)27)23-28-15(11-33-23)7-8-17(29)16-4-2-3-5-18(16)31-12-21(24)25/h2-6,9-11,21-22H,7-8,12-13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389097
PNG
(USRE46792, 309)
Show SMILES COc1ccc(cc1OCC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H20F2N2O4/c1-13-4-3-9-24-20(13)16(26)7-6-15-11-29-21(25-15)14-5-8-17(27-2)18(10-14)28-12-19(22)23/h3-5,8-11,19H,6-7,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389113
PNG
(USRE46792, 337)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCCC=C)c1
Show InChI InChI=1S/C25H25F2NO5/c1-3-5-14-31-23-15-17(10-13-22(23)33-25(26)27)24-28-18(16-32-24)11-12-20(29)19-8-6-7-9-21(19)30-4-2/h3,6-10,13,15-16,25H,1,4-5,11-12,14H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389123
PNG
(USRE46792, 349)
Show SMILES CCOc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ccccc2OCC)co1
Show InChI InChI=1S/C22H22F2N2O5/c1-3-28-17-8-6-5-7-16(17)20(27)25-12-15-13-30-21(26-15)14-9-10-18(31-22(23)24)19(11-14)29-4-2/h5-11,13,22H,3-4,12H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389125
PNG
(USRE46792, 351)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC=C)c1
Show InChI InChI=1S/C23H22F2N2O5/c1-3-11-30-20-12-15(9-10-19(20)32-23(24)25)22-27-16(14-31-22)13-26-21(28)17-7-5-6-8-18(17)29-4-2/h3,5-10,12,14,23H,1,4,11,13H2,2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389132
PNG
(USRE46792, 384)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H23N3O4/c1-13(2)28-18-10-15(7-8-17(18)26-4)21-24-16(12-27-21)11-23-20(25)19-14(3)6-5-9-22-19/h5-10,12-13H,11H2,1-4H3,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389039
PNG
(USRE46792, 36)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H23N3O4/c1-14-4-3-9-23-20(14)21(26)24-11-17-13-29-22(25-17)16-7-8-18(27-2)19(10-16)28-12-15-5-6-15/h3-4,7-10,13,15H,5-6,11-12H2,1-2H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389040
PNG
(USRE46792, 42)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2ccc(F)cc2OC)co1
Show InChI InChI=1S/C23H23FN2O5/c1-28-19-8-5-15(9-21(19)30-12-14-3-4-14)23-26-17(13-31-23)11-25-22(27)18-7-6-16(24)10-20(18)29-2/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389043
PNG
(USRE46792, 61)
Show SMILES CCCOc1cccnc1C(=O)NCc1coc(n1)-c1ccc(OC)c(OCC2CC2)c1
Show InChI InChI=1S/C24H27N3O5/c1-3-11-30-20-5-4-10-25-22(20)23(28)26-13-18-15-32-24(27-18)17-8-9-19(29-2)21(12-17)31-14-16-6-7-16/h4-5,8-10,12,15-16H,3,6-7,11,13-14H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389044
PNG
(USRE46792, 62)
Show SMILES COc1ccc(cc1OCC(C)C)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H25N3O4/c1-14(2)12-28-19-10-16(7-8-18(19)27-4)22-25-17(13-29-22)11-24-21(26)20-15(3)6-5-9-23-20/h5-10,13-14H,11-12H2,1-4H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389047
PNG
(USRE46792, 98)
Show SMILES FC(F)Oc1ccc(cc1OC(F)F)-c1nc(CCl)co1
Show InChI InChI=1S/C12H8ClF4NO3/c13-4-7-5-19-10(18-7)6-1-2-8(20-11(14)15)9(3-6)21-12(16)17/h1-3,5,11-12H,4H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389048
PNG
(USRE46792, 99)
Show SMILES NCc1coc(n1)-c1ccc(OC(F)F)c(OC(F)F)c1
Show InChI InChI=1S/C12H10F4N2O3/c13-11(14)20-8-2-1-6(3-9(8)21-12(15)16)10-18-7(4-17)5-19-10/h1-3,5,11-12H,4,17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389051
PNG
(USRE46792, 104)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC=C)c1
Show InChI InChI=1S/C24H25NO5/c1-4-14-29-23-15-17(10-13-22(23)27-3)24-25-18(16-30-24)11-12-20(26)19-8-6-7-9-21(19)28-5-2/h4,6-10,13,15-16H,1,5,11-12,14H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389054
PNG
(USRE46792, 112)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC(F)(F)F)c1
Show InChI InChI=1S/C23H22F3NO5/c1-3-30-19-7-5-4-6-17(19)18(28)10-9-16-13-31-22(27-16)15-8-11-20(29-2)21(12-15)32-14-23(24,25)26/h4-8,11-13H,3,9-10,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389055
PNG
(USRE46792, 116)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC2CCC2)c1
Show InChI InChI=1S/C26H29NO5/c1-3-30-23-10-5-4-9-21(23)22(28)13-12-20-17-32-26(27-20)19-11-14-24(29-2)25(15-19)31-16-18-7-6-8-18/h4-5,9-11,14-15,17-18H,3,6-8,12-13,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389057
PNG
(USRE46792, 129)
Show SMILES COc1ccc(cc1OCC(F)(F)F)-c1nc(CCC(=O)c2ncccc2OC)co1
Show InChI InChI=1S/C21H19F3N2O5/c1-28-16-8-5-13(10-18(16)31-12-21(22,23)24)20-26-14(11-30-20)6-7-15(27)19-17(29-2)4-3-9-25-19/h3-5,8-11H,6-7,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389089
PNG
(USRE46792, 283)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C25H25F2NO5/c1-30-22-11-8-17(12-23(22)31-13-16-6-7-16)25-28-18(14-33-25)9-10-20(29)19-4-2-3-5-21(19)32-15-24(26)27/h2-5,8,11-12,14,16,24H,6-7,9-10,13,15H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389094
PNG
(USRE46792, 299)
Show SMILES CCOc1ccc(cc1OCC)-c1nc(CCC(=O)c2ccc(F)cc2OCC)co1
Show InChI InChI=1S/C24H26FNO5/c1-4-28-21-12-7-16(13-23(21)30-6-3)24-26-18(15-31-24)9-11-20(27)19-10-8-17(25)14-22(19)29-5-2/h7-8,10,12-15H,4-6,9,11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389099
PNG
(USRE46792, 312)
Show SMILES CCC(CC)Oc1cc(ccc1OC)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C24H28N2O4/c1-5-19(6-2)30-22-14-17(9-12-21(22)28-4)24-26-18(15-29-24)10-11-20(27)23-16(3)8-7-13-25-23/h7-9,12-15,19H,5-6,10-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389104
PNG
(USRE46792, 328)
Show SMILES Cc1cccnc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCC2CC2)c1
Show InChI InChI=1S/C23H22F2N2O4/c1-14-3-2-10-26-21(14)18(28)8-7-17-13-30-22(27-17)16-6-9-19(31-23(24)25)20(11-16)29-12-15-4-5-15/h2-3,6,9-11,13,15,23H,4-5,7-8,12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389109
PNG
(USRE46792, 333)
Show SMILES CCOc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H20F2N2O4/c1-3-27-18-11-14(6-9-17(18)29-21(22)23)20-25-15(12-28-20)7-8-16(26)19-13(2)5-4-10-24-19/h4-6,9-12,21H,3,7-8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389111
PNG
(USRE46792, 335)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCC=C)c1
Show InChI InChI=1S/C24H23F2NO5/c1-3-13-30-22-14-16(9-12-21(22)32-24(25)26)23-27-17(15-31-23)10-11-19(28)18-7-5-6-8-20(18)29-4-2/h3,5-9,12,14-15,24H,1,4,10-11,13H2,2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389118
PNG
(USRE46792, 342)
Show SMILES CCC(CC)Oc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C23H25F2N3O4/c1-4-17(5-2)31-19-11-15(8-9-18(19)32-23(24)25)22-28-16(13-30-22)12-27-21(29)20-14(3)7-6-10-26-20/h6-11,13,17,23H,4-5,12H2,1-3H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389126
PNG
(USRE46792, 352)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OC(C)C)c1
Show InChI InChI=1S/C23H24F2N2O5/c1-4-29-18-8-6-5-7-17(18)21(28)26-12-16-13-30-22(27-16)15-9-10-19(32-23(24)25)20(11-15)31-14(2)3/h5-11,13-14,23H,4,12H2,1-3H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389031
PNG
(USRE46792, 14)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC)c(OCC(C)C)c1
Show InChI InChI=1S/C24H28N2O5/c1-5-29-20-9-7-6-8-19(20)23(27)25-13-18-15-31-24(26-18)17-10-11-21(28-4)22(12-17)30-14-16(2)3/h6-12,15-16H,5,13-14H2,1-4H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389037
PNG
(USRE46792, 32)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2ccccc2OCC(F)(F)F)co1
Show InChI InChI=1S/C24H23F3N2O5/c1-31-20-9-8-16(10-21(20)32-12-15-6-7-15)23-29-17(13-33-23)11-28-22(30)18-4-2-3-5-19(18)34-14-24(25,26)27/h2-5,8-10,13,15H,6-7,11-12,14H2,1H3,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389038
PNG
(USRE46792, 35)
Show SMILES COc1ccc(cc1OC1CCCC1)-c1nc(CNC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C24H26N2O5/c1-28-20-10-6-5-9-19(20)23(27)25-14-17-15-30-24(26-17)16-11-12-21(29-2)22(13-16)31-18-7-3-4-8-18/h5-6,9-13,15,18H,3-4,7-8,14H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389056
PNG
(USRE46792, 126)
Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CCC(=O)c2ncccc2OC)co1
Show InChI InChI=1S/C23H24N2O5/c1-27-19-10-7-16(12-21(19)29-13-15-5-6-15)23-25-17(14-30-23)8-9-18(26)22-20(28-2)4-3-11-24-22/h3-4,7,10-12,14-15H,5-6,8-9,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389059
PNG
(USRE46792, 133)
Show SMILES CCOc1cccnc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCC2CC2)c1
Show InChI InChI=1S/C24H26N2O5/c1-3-29-21-5-4-12-25-23(21)19(27)10-9-18-15-31-24(26-18)17-8-11-20(28-2)22(13-17)30-14-16-6-7-16/h4-5,8,11-13,15-16H,3,6-7,9-10,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389068
PNG
(USRE46792, 155)
Show SMILES COc1ccc(cc1OCC(F)(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C21H19F3N2O4/c1-13-4-3-9-25-19(13)16(27)7-6-15-11-29-20(26-15)14-5-8-17(28-2)18(10-14)30-12-21(22,23)24/h3-5,8-11H,6-7,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389074
PNG
(USRE46792, 172)
Show SMILES CCOc1cc(ccc1OC)-c1nc(CCC(=O)c2ccccc2OC)co1
Show InChI InChI=1S/C22H23NO5/c1-4-27-21-13-15(9-12-20(21)26-3)22-23-16(14-28-22)10-11-18(24)17-7-5-6-8-19(17)25-2/h5-9,12-14H,4,10-11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389077
PNG
(USRE46792, 181)
Show SMILES CCOc1ccc(cc1OCC)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H24N2O4/c1-4-26-19-11-8-16(13-20(19)27-5-2)22-24-17(14-28-22)9-10-18(25)21-15(3)7-6-12-23-21/h6-8,11-14H,4-5,9-10H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389081
PNG
(USRE46792, 224)
Show SMILES COc1ccc(cc1OC(C)C)-c1nc(CCC(=O)c2ccccc2OCC=C)co1
Show InChI InChI=1S/C25H27NO5/c1-5-14-29-22-9-7-6-8-20(22)21(27)12-11-19-16-30-25(26-19)18-10-13-23(28-4)24(15-18)31-17(2)3/h5-10,13,15-17H,1,11-12,14H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389082
PNG
(USRE46792, 232)
Show SMILES COCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(O)c1
Show InChI InChI=1S/C21H21NO6/c1-25-13-28-19-6-4-3-5-16(19)17(23)9-8-15-12-27-21(22-15)14-7-10-20(26-2)18(24)11-14/h3-7,10-12,24H,8-9,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389091
PNG
(USRE46792, 285)
Show SMILES COc1ccc(cc1OCC(C)C)-c1nc(CCC(=O)c2ccccc2OCC(F)F)co1
Show InChI InChI=1S/C25H27F2NO5/c1-16(2)13-31-23-12-17(8-11-22(23)30-3)25-28-18(14-33-25)9-10-20(29)19-6-4-5-7-21(19)32-15-24(26)27/h4-8,11-12,14,16,24H,9-10,13,15H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389101
PNG
(USRE46792, 315)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC)c(OCCF)c1
Show InChI InChI=1S/C23H24FNO5/c1-3-28-20-7-5-4-6-18(20)19(26)10-9-17-15-30-23(25-17)16-8-11-21(27-2)22(14-16)29-13-12-24/h4-8,11,14-15H,3,9-10,12-13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389102
PNG
(USRE46792, 318)
Show SMILES CCOc1ccc(cc1OCC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H22F2N2O4/c1-3-28-18-9-6-15(11-19(18)29-13-20(23)24)22-26-16(12-30-22)7-8-17(27)21-14(2)5-4-10-25-21/h4-6,9-12,20H,3,7-8,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389108
PNG
(USRE46792, 332)
Show SMILES CC(C)Oc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1
Show InChI InChI=1S/C22H22F2N2O4/c1-13(2)29-19-11-15(6-9-18(19)30-22(23)24)21-26-16(12-28-21)7-8-17(27)20-14(3)5-4-10-25-20/h4-6,9-13,22H,7-8H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389112
PNG
(USRE46792, 336)
Show SMILES CCOc1ccccc1C(=O)CCc1coc(n1)-c1ccc(OC(F)F)c(OCC2CC2)c1
Show InChI InChI=1S/C25H25F2NO5/c1-2-30-21-6-4-3-5-19(21)20(29)11-10-18-15-32-24(28-18)17-9-12-22(33-25(26)27)23(13-17)31-14-16-7-8-16/h3-6,9,12-13,15-16,25H,2,7-8,10-11,14H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389129
PNG
(USRE46792, 355)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OC(CC)CC)c1
Show InChI InChI=1S/C25H28F2N2O5/c1-4-18(5-2)33-22-13-16(11-12-21(22)34-25(26)27)24-29-17(15-32-24)14-28-23(30)19-9-7-8-10-20(19)31-6-3/h7-13,15,18,25H,4-6,14H2,1-3H3,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389130
PNG
(USRE46792, 382)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC(F)F)c1
Show InChI InChI=1S/C22H20F4N2O5/c1-2-30-16-6-4-3-5-15(16)20(29)27-10-14-11-32-21(28-14)13-7-8-17(33-22(25)26)18(9-13)31-12-19(23)24/h3-9,11,19,22H,2,10,12H2,1H3,(H,27,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389131
PNG
(USRE46792, 383)
Show SMILES CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OCC(F)(F)F)c1
Show InChI InChI=1S/C22H19F5N2O5/c1-2-31-16-6-4-3-5-15(16)19(30)28-10-14-11-32-20(29-14)13-7-8-17(34-21(23)24)18(9-13)33-12-22(25,26)27/h3-9,11,21H,2,10,12H2,1H3,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM389036
PNG
(USRE46792, 29)
Show SMILES CCOc1cccnc1C(=O)NCc1coc(n1)-c1ccc(OC)c(OC2CCCC2)c1
Show InChI InChI=1S/C24H27N3O5/c1-3-30-20-9-6-12-25-22(20)23(28)26-14-17-15-31-24(27-17)16-10-11-19(29-2)21(13-16)32-18-7-4-5-8-18/h6,9-13,15,18H,3-5,7-8,14H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



University of Tampere



Assay Description
Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...

J Med Chem 52: 646-54 (2009)


BindingDB Entry DOI: 10.7270/Q2DZ0BNN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%