BDBM389109 USRE46792, 333

SMILES: CCOc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1

InChI Key: InChIKey=LXTJFOJYIUPVNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389109 (USRE46792, 333) Show SMILES CCOc1cc(ccc1OC(F)F)-c1nc(CCC(=O)c2ncccc2C)co1 Show InChI InChI=1S/C21H20F2N2O4/c1-3-27-18-11-14(6-9-17(18)29-21(22)23)20-25-15(12-28-20)7-8-16(26)19-13(2)5-4-10-24-19/h4-6,9-12,21H,3,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
					More data for this Ligand-Target Pair