Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM389117'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389117 (USRE46792, 341) Show SMILES CC(C)Oc1cc(ccc1OC(F)F)-c1nc(CNC(=O)c2ncccc2C)co1 Show InChI InChI=1S/C21H21F2N3O4/c1-12(2)29-17-9-14(6-7-16(17)30-21(22)23)20-26-15(11-28-20)10-25-19(27)18-13(3)5-4-8-24-18/h4-9,11-12,21H,10H2,1-3H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
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