BDBM389070 USRE46792, 159

SMILES: COc1ccc(cc1OC1Cc2ccccc2C1)-c1nc(CCC(=O)c2ncccc2C)co1

InChI Key: InChIKey=PGVCQJRYMXMAIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389070 (USRE46792, 159) Show SMILES COc1ccc(cc1OC1Cc2ccccc2C1)-c1nc(CCC(=O)c2ncccc2C)co1 Show InChI InChI=1S/C28H26N2O4/c1-18-6-5-13-29-27(18)24(31)11-10-22-17-33-28(30-22)21-9-12-25(32-2)26(16-21)34-23-14-19-7-3-4-8-20(19)15-23/h3-9,12-13,16-17,23H,10-11,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
					More data for this Ligand-Target Pair