BDBM389041 USRE46792, 43

SMILES: COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2c(F)cccc2OC)co1

InChI Key: InChIKey=WOXVOYUUIGLPQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM389041 (USRE46792, 43) Show SMILES COc1ccc(cc1OCC1CC1)-c1nc(CNC(=O)c2c(F)cccc2OC)co1 Show InChI InChI=1S/C23H23FN2O5/c1-28-18-9-8-15(10-20(18)30-12-14-6-7-14)23-26-16(13-31-23)11-25-22(27)21-17(24)4-3-5-19(21)29-2/h3-5,8-10,13-14H,6-7,11-12H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description Necessary amounts of test compounds were weighed, and 100% dimethylsulfoxide (DMSO) was added thereto to adjust the concentration to 10 mM. The solut...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2DZ0BNN
					More data for this Ligand-Target Pair